perfosfamide has been researched along with methotrexate in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Affronti, ML; Bast, RC; Eggleston, S; Johnston, C; Jones, RB; Rosner, GL; Ross, M; Shpall, EJ; Tepperburg, M; Vandermark, R | 1 |
| Dörken, B; Fliedner, TM; Ho, AD; Hunstein, W; Körbling, M; Tischbirek, K; Zipperle, G | 1 |
| Bearman, SI; Jones, RB; Myers, S; Purdy, M; Shpall, EJ; Stemmer, SM | 1 |
| Hanada, R; Hongo, T; Horikoshi, Y; Sakurai, M; Yajima, S | 1 |
| Akutsu, M; Bai, L; Furukawa, Y; Ichikawa, A; Kano, Y; Kon, K; Suzuki, K; Tsunoda, S | 1 |
| Adhikari, D; Banerjee, D; Bertino, JR; Colvin, M; Hilton, J; Mineishi, S; Sadelain, M; Takebe, N; Zhao, SC | 1 |
| Colvin, M; Duan, X; Jia, SF; Kleinerman, ES; Lafleur, EA; Zhou, Z | 1 |
| Blomqvist, C; Larsson, R; Nygren, P; Villman, K | 1 |
| Haskova, P; Jansova, H; Kalinowski, DS; Machacek, M; Potuckova, E; Richardson, DR; Richardson, V; Simunek, T; Tichotova, L; Vavrova, A | 1 |
| Chen, K; Gao, C; Li, X; Luo, J; Qin, K; Wang, C; Wang, Q; Zhao, W; Zhao, X | 1 |
| Chen, KL; Li, XF; Luo, J; Niu, HQ; Qin, KL; Zhao, WP; Zhao, XC | 1 |
2 trial(s) available for perfosfamide and methotrexate
| Article | Year |
|---|---|
4-Hydroperoxycyclophosphamide purging of breast cancer from the mononuclear cell fraction of bone marrow in patients receiving high-dose chemotherapy and autologous marrow support: a phase I trial.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Bone Neoplasms; Brain Neoplasms; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Evaluation; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplastic Stem Cells; Survival Rate | 1991 |
New strategies in marrow purging for breast cancer patients receiving high-dose chemotherapy with autologous bone marrow transplantation.
Topics: Amifostine; Antigens, CD; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Purging; Bone Marrow Transplantation; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Stem Cells | 1993 |
9 other study(ies) available for perfosfamide and methotrexate
| Article | Year |
|---|---|
Autologous transplantation of a bone marrow graft manipulated by chemoseparation to eliminate residual tumor cells.
Topics: Bone Marrow; Bone Marrow Transplantation; Brain Neoplasms; Cyclophosphamide; Freezing; Humans; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Tissue Preservation; Transplantation, Autologous | 1983 |
In vitro drug sensitivity testing can predict induction failure and early relapse of childhood acute lymphoblastic leukemia.
Topics: Aclarubicin; Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bleomycin; Bone Marrow; Cell Survival; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Etoposide; Follow-Up Studies; Humans; Infant; Infant, Newborn; Life Tables; Melphalan; Methotrexate; Mitomycin; Mitoxantrone; Neoplastic Stem Cells; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Recurrence; Remission Induction; Tumor Cells, Cultured; Vincristine | 1997 |
In vitro cytotoxic effects of fludarabine (2-F-ara-A) in combination with commonly used antileukemic agents by isobologram analysis.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Cell Survival; Cyclophosphamide; Cytarabine; Dose-Response Relationship, Drug; Doxorubicin; Drug Screening Assays, Antitumor; Drug Synergism; Etoposide; Humans; Hydroxyurea; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Methotrexate; Neoplastic Stem Cells; Tumor Cells, Cultured; Vidarabine; Vidarabine Phosphate; Vincristine | 2000 |
Generation of dual resistance to 4-hydroperoxycyclophosphamide and methotrexate by retroviral transfer of the human aldehyde dehydrogenase class 1 gene and a mutated dihydrofolate reductase gene.
Topics: 3T3 Cells; Aldehyde Dehydrogenase; Animals; Antigens, CD34; Antimetabolites, Antineoplastic; Blotting, Western; Bone Marrow Transplantation; Cyclophosphamide; DNA, Complementary; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Gene Transfer Techniques; Hematopoietic Stem Cells; Humans; Methotrexate; Mice; Models, Genetic; Mutation; Polymerase Chain Reaction; Retroviridae; RNA; Tetrahydrofolate Dehydrogenase; Time Factors; Transduction, Genetic | 2001 |
Interleukin-12 enhances the sensitivity of human osteosarcoma cells to 4-hydroperoxycyclophosphamide by a mechanism involving the Fas/Fas-ligand pathway.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Separation; Cisplatin; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Fas Ligand Protein; fas Receptor; Flow Cytometry; Humans; Immunohistochemistry; Inhibitory Concentration 50; Interleukin-12; Membrane Glycoproteins; Methotrexate; Osteosarcoma; RNA, Messenger; Time Factors; Transfection; Up-Regulation | 2004 |
Predictive value of in vitro assessment of cytotoxic drug activity in advanced breast cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Survival; Cyclophosphamide; Disease Progression; Docetaxel; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Epirubicin; Female; Fluorometry; Fluorouracil; Humans; Methotrexate; Neoplasm Staging; Predictive Value of Tests; Prospective Studies; Quality Control; Retrospective Studies; Taxoids; Treatment Outcome; Tumor Cells, Cultured | 2005 |
Quantitative analysis of the anti-proliferative activity of combinations of selected iron-chelating agents and clinically used anti-neoplastic drugs.
Topics: Aldehydes; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Proliferation; Cyclophosphamide; Deferoxamine; Doxorubicin; Drug Synergism; Fluorouracil; Humans; Hydrazones; Iron Chelating Agents; MCF-7 Cells; Methotrexate; Paclitaxel; Tamoxifen; Thiosemicarbazones | 2014 |
Methotrexate Combined with 4-Hydroperoxycyclophosphamide Downregulates Multidrug-Resistance P-Glycoprotein Expression Induced by Methotrexate in Rheumatoid Arthritis Fibroblast-Like Synoviocytes via the JAK2/STAT3 Pathway.
Topics: Apoptosis; Arthritis, Rheumatoid; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Cyclophosphamide; Drug Resistance, Multiple; Drug Therapy, Combination; Fibroblasts; Gene Expression Regulation; Humans; Janus Kinase 2; Methotrexate; Signal Transduction; STAT3 Transcription Factor; Synoviocytes | 2018 |
Combination of 4-hydroperoxy cyclophosphamide and methotrexate inhibits IL-6/sIL-6R-induced RANKL expression in fibroblast-like synoviocytes via suppression of the JAK2/STAT3 and p38MAPK signaling pathway.
Topics: Arthritis, Rheumatoid; Cells, Cultured; Cyclophosphamide; Drug Therapy, Combination; Fibroblasts; Gene Expression Regulation; Humans; Imidazoles; Interleukin-6; Janus Kinase 2; Methotrexate; p38 Mitogen-Activated Protein Kinases; Pyridines; RANK Ligand; Receptors, Interleukin-6; Signal Transduction; STAT3 Transcription Factor; Synoviocytes; Tyrphostins | 2018 |