Page last updated: 2024-08-23

perfosfamide and melphalan

perfosfamide has been researched along with melphalan in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19907 (35.00)18.7374
1990's11 (55.00)18.2507
2000's1 (5.00)29.6817
2010's1 (5.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Deutsch, WA; Erickson, LC; Futscher, BW; Grabowski, DT; Kelley, MR; Pieper, RO1
Bast, RC; Lidor, YJ; Peters, WP; Shpall, EJ1
Cheung, NK; Gulati, SC; Heller, G; Kushner, BH; O'Reilly, RJ1
al-Achi, A; Henner, WD; Holden, SA; Rosbe, KW; Shea, TC; Teicher, BA; Wang, YY1
Kohn, FR; Sladek, NE1
Linch, DC; Singer, CR1
Jinks, S; Loverock, PS; Millar, BC; Ormerod, MG; Payne, AW; Tilby, MJ1
Greinix, H; Höcker, P; Kaulfersch, W; Slace, I; Urban, C1
Bosanquet, AG1
Benckhuysen, C; van der Steen, J; van Wichen, BH1
Kaddurah-Daouk, R; Kufe, DW; Liu, J; Menon, K; Northey, D; Teicher, BA1
Aaron, RH; Bigner, DD; Colvin, OM; Elion, GB; Friedman, HS; Graham, M; Keir, S1
Barnett, MJ; Connors, JM; Klingemann, HG; O'Reilly, SE; Phillips, GL; Reece, DE; Shepherd, JD; Sutherland, HJ1
Dupuis, NP; Emi, Y; Goff, DA; Robinson, MF; Teicher, BA1
Hanada, R; Hongo, T; Horikoshi, Y; Sakurai, M; Yajima, S1
Richardson, ME; Siemann, DW1
Aebi, S; Fink, D; Haas, M; Howell, SB; Kim, HK; Nebel, S; Norris, PS1
Aebi, S; Fink, D; Fink, JL; Gordon, R; Howell, SB; Kim, HK; Zheng, H1
Clutter, SD; Fortney, JE; Gibson, LF1
Andersson, BS; Hassan, M; Valdez, BC1

Reviews

1 review(s) available for perfosfamide and melphalan

ArticleYear
Stability of solutions of antineoplastic agents during preparation and storage for in vitro assays. General considerations, the nitrosoureas and alkylating agents.
    Cancer chemotherapy and pharmacology, 1985, Volume: 14, Issue:2

    Topics: Alkylation; Antineoplastic Agents; Carmustine; Chlorambucil; Colony-Forming Units Assay; Cyclophosphamide; Drug Storage; Hydrogen-Ion Concentration; Lomustine; Mathematics; Melphalan; Nimustine; Nitrosourea Compounds; Solutions; Temperature; Tumor Stem Cell Assay

1985

Trials

1 trial(s) available for perfosfamide and melphalan

ArticleYear
Treatment of multiple myeloma with intensive chemotherapy followed by autologous BMT using marrow purged with 4-hydroperoxycyclophosphamide.
    Bone marrow transplantation, 1993, Volume: 11, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Purging; Bone Marrow Transplantation; Busulfan; Clinical Protocols; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dexamethasone; Female; Humans; Life Tables; Male; Melphalan; Middle Aged; Multiple Myeloma; Survival Analysis; Transplantation, Autologous; Vincristine

1993

Other Studies

18 other study(ies) available for perfosfamide and melphalan

ArticleYear
Expression of ribosomal phosphoprotein PO is induced by antitumor agents and increased in Mer- human tumor cell lines.
    Carcinogenesis, 1992, Volume: 13, Issue:2

    Topics: Antineoplastic Agents; Blotting, Northern; Blotting, Southern; Cyclophosphamide; DNA Probes; DNA Repair; Electrophoresis, Agar Gel; Gene Expression; Humans; Mechlorethamine; Melphalan; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Phosphoproteins; Ribosomal Proteins; Tumor Cells, Cultured

1992
Synergistic cytotoxicity of different alkylating agents for epithelial ovarian cancer.
    International journal of cancer, 1991, Nov-11, Volume: 49, Issue:5

    Topics: Alkylating Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Cell Division; Cisplatin; Cyclophosphamide; Drug Synergism; Female; Humans; Melphalan; Ovarian Neoplasms; Thiotepa; Tumor Cells, Cultured

1991
Autografting with bone marrow exposed to multiple courses of very high dose cyclophosphamide in vivo and to 4-hydroperoxycyclophosphamide in vitro.
    Medical and pediatric oncology, 1990, Volume: 18, Issue:6

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Blood Platelets; Bone Marrow; Bone Marrow Transplantation; Child, Preschool; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Hematopoiesis; Humans; Infant; Melphalan; Neuroblastoma; Neutrophils; Thiotepa; Vincristine

1990
Cross-resistance and glutathione-S-transferase-pi levels among four human melanoma cell lines selected for alkylating agent resistance.
    Cancer research, 1989, Nov-15, Volume: 49, Issue:22

    Topics: Alkylating Agents; Antineoplastic Agents; Blotting, Northern; Carmustine; Cell Line; Cell Survival; Clone Cells; Cyclophosphamide; Drug Resistance; Glutathione Transferase; Humans; Melanoma; Melphalan; RNA, Neoplasm; Tumor Cells, Cultured

1989
Aldehyde dehydrogenase activity as the basis for the relative insensitivity of murine pluripotent hematopoietic stem cells to oxazaphosphorines.
    Biochemical pharmacology, 1985, Oct-01, Volume: 34, Issue:19

    Topics: Acrolein; Aldehyde Dehydrogenase; Animals; Bone Marrow Cells; Cisplatin; Colony-Forming Units Assay; Cyanamide; Cyclophosphamide; Disulfiram; Ditiocarb; Drug Synergism; Granulocytes; Hematopoietic Stem Cells; Male; Melphalan; Mice; Mice, Inbred BALB C; Nitrogen Mustard Compounds; Organophosphorus Compounds; Phosphinic Acids; Phosphoramide Mustards

1985
Comparison of the sensitivity of normal and leukaemic myeloid progenitors to in-vitro incubation with cytotoxic drugs: a study of pharmacological purging.
    Leukemia research, 1987, Volume: 11, Issue:11

    Topics: Antineoplastic Agents; Bone Marrow; Bone Marrow Transplantation; Cell Survival; Clone Cells; Cyclophosphamide; Cytarabine; Etoposide; Granulocytes; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Melphalan; Transplantation, Autologous; Tumor Cells, Cultured

1987
Comparative studies of total cross-linking, cell survival and cell cycle perturbations in Chinese hamster cells treated with alkylating agents in vitro.
    Biochemical pharmacology, 1986, Apr-01, Volume: 35, Issue:7

    Topics: Alkylating Agents; Animals; Busulfan; Cell Cycle; Cell Line; Cell Survival; Cricetinae; Cricetulus; Cyclophosphamide; Dose-Response Relationship, Drug; Female; Half-Life; Melphalan; Ovary; Phosphoramide Mustards

1986
[Treatment of stage IV neuroblastoma with high-dose melphalan and autologous bone marrow transplantation following in vitro preliminary treatment of the bone marrow with the active cyclophosphamide derivative Asta Z-7654].
    Padiatrie und Padologie, 1986, Volume: 21, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Bone Neoplasms; Child, Preschool; Cyclophosphamide; Humans; Male; Melphalan; Neoplasm Staging; Neoplasms, Unknown Primary; Neuroblastoma

1986
Effects of alkylating agents on the DNA replication of cultured Yoshida sarcoma cells.
    Chemico-biological interactions, 1982, Mar-15, Volume: 39, Issue:2

    Topics: Alkylating Agents; Animals; Carmustine; Cell Division; Cell Survival; Chlorambucil; Cyclophosphamide; DNA Replication; Doxorubicin; Kinetics; Mechlorethamine; Melphalan; Mice; Sarcoma, Yoshida; Structure-Activity Relationship

1982
Cyclocreatine in cancer chemotherapy.
    Cancer chemotherapy and pharmacology, 1995, Volume: 35, Issue:5

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma, Small Cell; Carmustine; Cell Division; Cell Survival; Cisplatin; Creatinine; Cyclophosphamide; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Female; Humans; Injections, Intraperitoneal; Injections, Intravenous; Lung Neoplasms; Mammary Neoplasms, Experimental; Melphalan; Rats; Rats, Inbred F344; Tumor Cells, Cultured

1995
Busulfan therapy of central nervous system xenografts in athymic mice.
    Cancer chemotherapy and pharmacology, 1994, Volume: 35, Issue:2

    Topics: Animals; Brain Neoplasms; Busulfan; Child, Preschool; Cyclophosphamide; Female; Humans; Injections, Intraperitoneal; Male; Medulloblastoma; Melphalan; Mice; Mice, Nude; Neoplasm Transplantation; Transplantation, Heterologous; Tumor Cells, Cultured

1994
Antiangiogenic treatment (TNP-470/minocycline) increases tissue levels of anticancer drugs in mice bearing Lewis lung carcinoma.
    Oncology research, 1995, Volume: 7, Issue:5

    Topics: Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; Carmustine; Cell Hypoxia; Cell Survival; Cisplatin; Cyclohexanes; Cyclophosphamide; DNA, Neoplasm; Drug Combinations; Male; Melphalan; Mice; Mice, Inbred C57BL; Minocycline; O-(Chloroacetylcarbamoyl)fumagillol; Platinum; Sesquiterpenes; Tumor Cells, Cultured

1995
In vitro drug sensitivity testing can predict induction failure and early relapse of childhood acute lymphoblastic leukemia.
    Blood, 1997, Apr-15, Volume: 89, Issue:8

    Topics: Aclarubicin; Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bleomycin; Bone Marrow; Cell Survival; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Etoposide; Follow-Up Studies; Humans; Infant; Infant, Newborn; Life Tables; Melphalan; Methotrexate; Mitomycin; Mitoxantrone; Neoplastic Stem Cells; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Recurrence; Remission Induction; Tumor Cells, Cultured; Vincristine

1997
Tumor cell heterogeneity: impact on mechanisms of therapeutic drug resistance.
    International journal of radiation oncology, biology, physics, 1997, Nov-01, Volume: 39, Issue:4

    Topics: Aldehyde Dehydrogenase; Animals; Antineoplastic Agents, Alkylating; Cyclophosphamide; Drug Resistance, Neoplasm; Glutathione; Glutathione Transferase; Melphalan; Mice; Neoplasm Proteins; Sarcoma, Experimental; Tumor Cells, Cultured

1997
The effect of different chemotherapeutic agents on the enrichment of DNA mismatch repair-deficient tumour cells.
    British journal of cancer, 1998, Volume: 77, Issue:5

    Topics: Adenocarcinoma; Antineoplastic Agents; Carboplatin; Cell Separation; Cisplatin; Colorectal Neoplasms; Cyclophosphamide; DNA Repair; DNA, Neoplasm; Doxorubicin; Enzyme Inhibitors; Etoposide; Humans; Melphalan; Paclitaxel; Tamoxifen; Thioguanine; Tumor Cells, Cultured; Tumor Stem Cell Assay

1998
Resistance to cytotoxic drugs in DNA mismatch repair-deficient cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1997, Volume: 3, Issue:10

    Topics: Adaptor Proteins, Signal Transducing; Adenocarcinoma; Antineoplastic Agents; Carboplatin; Carrier Proteins; Cisplatin; Colorectal Neoplasms; Cyclophosphamide; DNA Adducts; DNA Damage; DNA Repair; DNA-Binding Proteins; DNA, Neoplasm; Doxorubicin; Drug Resistance, Neoplasm; Endometrial Neoplasms; Etoposide; Female; Fluorouracil; Humans; Melphalan; Methylnitronitrosoguanidine; Mutagenesis; MutL Protein Homolog 1; MutS Homolog 2 Protein; Neoplasm Proteins; Nuclear Proteins; Paclitaxel; Proto-Oncogene Proteins; Thioguanine; Tumor Cells, Cultured

1997
Chemotherapy disrupts activity of translational regulatory proteins in bone marrow stromal cells.
    Experimental hematology, 2006, Volume: 34, Issue:11

    Topics: Adaptor Proteins, Signal Transducing; Animals; Antimetabolites, Antineoplastic; Bone Marrow Cells; Cell Cycle Proteins; Cell Line; Cyclophosphamide; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Etoposide; Humans; Matrix Metalloproteinase 2; Melphalan; Mice; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Ribosomal Protein S6; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sirolimus; Stromal Cells; Structure-Activity Relationship; TOR Serine-Threonine Kinases

2006
Development of an assay for cellular efflux of pharmaceutically active agents and its relevance to understanding drug interactions.
    Experimental hematology, 2017, Volume: 52

    Topics: Antineoplastic Agents, Alkylating; Biological Transport; Busulfan; Cell Line, Tumor; Cell Survival; Chlorambucil; Cyclophosphamide; Drug Interactions; Ethacrynic Acid; Everolimus; Flow Cytometry; Fluoresceins; Humans; Ketoconazole; Melphalan; Multidrug Resistance-Associated Proteins; Reproducibility of Results; Sirolimus

2017