Page last updated: 2024-08-23

perfosfamide and mafosfamide

perfosfamide has been researched along with mafosfamide in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19903 (23.08)18.7374
1990's9 (69.23)18.2507
2000's1 (7.69)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Górski, A; Rychlik, G; Wasik, M1
Blomgren, H; Hallström, M1
Kohn, FR; Landkamer, GJ; Manthey, CL; Ramsay, NK; Sladek, NE1
Linch, DC; Singer, CR1
Hoon, DB; Jung, T; McBride, WH; Morton, DL; Naungayan, J; Nizze, A1
Douay, L; Giarratana, MC; Gorin, NC; Hu, C1
Rowley, SD1
Calabretta, B; Malaguarnera, L; Nieborowska-Skórska, M; Ratajczak, MZ; Skórski, T; Szczylik, C1
Sladek, NE; Sreerama, L1
Murgo, AJ; Weinberger, BB1
Morrow, CS; Smitherman, PK; Townsend, AJ1
Barnett, MJ; Brockington, DA; Klingemann, HG; Nantel, SH; Phillips, GL; Reece, DE; Shepherd, JD; Sutherland, HJ1
Farquhar, D; Wang, YQ1

Reviews

1 review(s) available for perfosfamide and mafosfamide

ArticleYear
Pharmacological bone marrow purging in autologous transplantation: focus on the cyclophosphamide derivatives.
    Critical reviews in oncology/hematology, 1993, Volume: 14, Issue:1

    Topics: Animals; Antineoplastic Agents; Bone Marrow Purging; Clinical Trials as Topic; Cyclophosphamide; Humans; Molecular Structure; Tumor Cells, Cultured

1993

Trials

1 trial(s) available for perfosfamide and mafosfamide

ArticleYear
Prolonged survival after intensive therapy and purged ABMT in patients with multiple myeloma.
    Bone marrow transplantation, 2000, Volume: 26, Issue:6

    Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Purging; Bone Marrow Transplantation; Combined Modality Therapy; Cyclophosphamide; Dexamethasone; Disease-Free Survival; Doxorubicin; Female; Humans; Interferon-alpha; Male; Middle Aged; Multiple Myeloma; Treatment Outcome; Vincristine

2000

Other Studies

11 other study(ies) available for perfosfamide and mafosfamide

ArticleYear
The effect of cyclophosphamide derivatives on cellular cytotoxicity (NK, ADCC) in vitro.
    Archivum immunologiae et therapiae experimentalis, 1990, Volume: 38, Issue:3-4

    Topics: Aged; Animals; Antibody-Dependent Cell Cytotoxicity; Cyclophosphamide; Cytotoxicity, Immunologic; Humans; Killer Cells, Natural; Mechlorethamine

1990
Possible role of acrolein in oxazaphosphorine-induced enhancement of immunological reactivity.
    Cancer immunology, immunotherapy : CII, 1990, Volume: 31, Issue:4

    Topics: Acrolein; Aldehydes; Antineoplastic Agents; Concanavalin A; Cyclophosphamide; Humans; Immunity, Cellular; Lymphocytes; Mitogens; Mitosis; T-Lymphocytes; T-Lymphocytes, Regulatory

1990
Effect of aldehyde dehydrogenase inhibitors on the ex vivo sensitivity of human multipotent and committed hematopoietic progenitor cells and malignant blood cells to oxazaphosphorines.
    Cancer research, 1987, Jun-15, Volume: 47, Issue:12

    Topics: Aldehyde Dehydrogenase; Animals; Colony-Forming Units Assay; Cyanamide; Cyclophosphamide; Disulfiram; Ditiocarb; Drug Resistance; Enzyme Inhibitors; Hematopoietic Stem Cells; Humans; Leukemia L1210; Mice; NAD; Organophosphorus Compounds; Phosphinic Acids; Phosphoramide Mustards

1987
Comparison of the sensitivity of normal and leukaemic myeloid progenitors to in-vitro incubation with cytotoxic drugs: a study of pharmacological purging.
    Leukemia research, 1987, Volume: 11, Issue:11

    Topics: Antineoplastic Agents; Bone Marrow; Bone Marrow Transplantation; Cell Survival; Clone Cells; Cyclophosphamide; Cytarabine; Etoposide; Granulocytes; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Melphalan; Transplantation, Autologous; Tumor Cells, Cultured

1987
Cyclophosphamide-induced alterations in human monocyte functions.
    Journal of leukocyte biology, 1987, Volume: 42, Issue:6

    Topics: Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Humans; Immunity, Cellular; Interleukin-1; Leukocytes, Mononuclear; Melanoma; Tumor Necrosis Factor-alpha; Vaccination

1987
Amifostine (WR-2721) protects normal haematopoietic stem cells against cyclophosphamide derivatives' toxicity without compromising their antileukaemic effects.
    European journal of cancer (Oxford, England : 1990), 1995, Volume: 31A Suppl 1

    Topics: Amifostine; Antineoplastic Agents; Bone Marrow Purging; Bone Marrow Transplantation; Cyclophosphamide; Dose-Response Relationship, Drug; Hematopoietic Stem Cells; Humans; Leukemia; Neoplastic Stem Cells

1995
Bone marrow purging, 4-hydroperoxycyclophosphamide, and the FDA.
    Journal of hematotherapy, 1993,Fall, Volume: 2, Issue:3

    Topics: Acute Disease; Bone Marrow; Bone Marrow Purging; Clinical Trials as Topic; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cyclophosphamide; Drug Industry; Drug Utilization; Ethics, Medical; Humans; Leukemia, Myeloid; Multicenter Studies as Topic; Neoplasm, Residual; Treatment Outcome; United States; United States Food and Drug Administration

1993
Successful mafosfamide purging of bone marrow from chronic myelogenous leukemia (CML) cells.
    Folia histochemica et cytobiologica, 1993, Volume: 31, Issue:4

    Topics: Antineoplastic Agents; Blast Crisis; Bone Marrow; Bone Marrow Purging; Colony-Forming Units Assay; Cyclophosphamide; Drug Screening Assays, Antitumor; Humans; Leukemia, Myeloid, Chronic-Phase; Oligonucleotide Probes; Polymerase Chain Reaction; Tumor Cells, Cultured

1993
Identification and characterization of a novel class 3 aldehyde dehydrogenase overexpressed in a human breast adenocarcinoma cell line exhibiting oxazaphosphorine-specific acquired resistance.
    Biochemical pharmacology, 1993, Jun-22, Volume: 45, Issue:12

    Topics: Adenocarcinoma; Aldehyde Dehydrogenase; Benzaldehydes; Breast Neoplasms; Cell Line; Cyclophosphamide; Drug Resistance; Gastric Mucosa; Gene Expression Regulation, Enzymologic; Humans; Hydrogen-Ion Concentration; Isoenzymes; NAD; NADP; Subcellular Fractions; Temperature

1993
Combined expression of multidrug resistance protein (MRP) and glutathione S-transferase P1-1 (GSTP1-1) in MCF7 cells and high level resistance to the cytotoxicities of ethacrynic acid but not oxazaphosphorines or cisplatin.
    Biochemical pharmacology, 1998, Oct-15, Volume: 56, Issue:8

    Topics: Antineoplastic Agents; Cell Survival; Cisplatin; Cyclophosphamide; Cytoprotection; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Ethacrynic Acid; Glutathione Transferase; Humans; Membrane Proteins; Transfection; Tumor Cells, Cultured

1998
Aldophosphamide acetal diacetate and structural analogues: synthesis and cytotoxicity studies.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:1

    Topics: Animals; Antineoplastic Agents; Carboxylesterase; Carboxylic Ester Hydrolases; Cell Survival; Drug Screening Assays, Antitumor; Leukemia L1210; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; Phosphoramide Mustards; Prodrugs; Structure-Activity Relationship

1991