perfluoro-1-4-7-10-13-pentaoxacyclopentadecane and perflubron

The method employs cycling of the readout gradient direction to alternate the spatial orientation of the off-resonance chemical shift artifacts, which are subsequently removed by iterative sparse deconvolution. Noise robustness and separation was investigated by numerical simulations. Mixtures of fluorinated oils (PFCE and PFOB) were measured on a 7T MR scanner to identify the relation between. The method requires minimal sequence adaptation and is therefore easily implemented on different MRI systems. Simulations, phantom experiments, and in-vivo measurements in mice showed effective separation and removal of chemical shift artifacts below noise level. We foresee applicability for simultaneous in-vivo imaging of

Topics: Algorithms; Animals; Artifacts; Cell Tracking; Computer Simulation; Contrast Media; Crown Ethers; Fluorine; Fluorine-19 Magnetic Resonance Imaging; Fluorocarbons; Hydrocarbons, Brominated; Image Processing, Computer-Assisted; Injections, Intramuscular; Liver; Male; Mice; Nanoparticles; Phantoms, Imaging; Spleen

To characterize and optimize. The T. The loss of acquisition efficiency due to parameter settings optimized for the wrong temperature and cellular condition was limited to 13%. The detection limits of all PFCs were lower at 24 °C than at 37 °C and varied from 11.8 ± 3.0 mM for PFCE at 24 °C to 379.9 ± 51.8 mM for PFOB at 37 °C.. Optimizing

Topics: Crown Ethers; Ethers; Fluorine; Fluorocarbons; Hydrocarbons, Brominated; Image Enhancement; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Phantoms, Imaging; Reproducibility of Results; Sensitivity and Specificity