perchlorate has been researched along with thyroxine in 39 studies
| Studies (perchlorate) | Trials (perchlorate) | Recent Studies (post-2010) (perchlorate) | Studies (thyroxine) | Trials (thyroxine) | Recent Studies (post-2010) (thyroxine) |
|---|---|---|---|---|---|
| 768 | 3 | 396 | 38,989 | 1,410 | 6,550 |
| Protein | Taxonomy | perchlorate (IC50) | thyroxine (IC50) |
|---|---|---|---|
| Transthyretin | Homo sapiens (human) | 2.1939 | |
| UDP-glucuronosyltransferase 1A1 | Homo sapiens (human) | 5.25 | |
| Solute carrier organic anion transporter family member 4C1 | Homo sapiens (human) | 8 | |
| Bile acid receptor | Homo sapiens (human) | 7.86 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (7.69) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 16 (41.03) | 29.6817 |
| 2010's | 18 (46.15) | 24.3611 |
| 2020's | 2 (5.13) | 2.80 |
| Authors | Studies |
|---|---|
| ENNECKER, C; KESSLER, FJ; KRUSKEMPER, HL | 1 |
| TONG, W | 1 |
| SCHOENBAUM, E; SELLERS, EA | 1 |
| Bradford, CM; Carr, JA; Rinchard, J; Theodorakis, C | 1 |
| Sato, K | 1 |
| Degitz, SJ; Helbing, CC; Holcombe, GW; Kosian, PA; Tietge, J; Veldhoen, N; Zhang, F | 1 |
| Beck, B; Blount, BC; Braverman, LE; Firek, A; He, X; Magnani, B; Pearce, EN; Pino, S; Seeley, M | 1 |
| Carr, JA; Hu, F; Mukhi, S; Patiño, R; Sharma, B | 1 |
| Blount, BC; Caldwell, KL; Osterloh, JD; Pirkle, JL; Valentin-Blasini, L | 1 |
| Mukhi, S; Patiño, R; Torres, L | 1 |
| Beccaria, L; Beck-Peccoz, P; Carletto, M; Cortinovis, F; Fugazzola, L; Longari, V; Mannavola, D; Persani, L; Vannucchi, G; Vigone, MC; Weber, G | 1 |
| Howd, R; Miller, MD; Steinmaus, C | 1 |
| Amitai, Y; Blount, BC; Fisher, N; Israeli, A; Leventhal, A; Lewis, M; Sack, J; Valentin-Blasini, L; Wasser, J; Winston, G | 1 |
| Gilbert, ME; Sui, L | 1 |
| Gibbs, JP; Van Landingham, C | 1 |
| Bernardini, N; Botta, R; Calebiro, D; de Filippis, T; Fausto, AM; Giorgi, F; Ippolito, C; Lisi, S; Madsen, P; Marcocci, C; Marinò, M; Mattii, L; Persani, L; Petersen, CM; Pinchera, A; Taddei, AR | 1 |
| Braunbeck, T; Grim, KC; Iguchi, T; Ohta, Y; Tietge, J; Tooi, O; Touart, L; Wolf, DC; Wolfe, M | 1 |
| Andersen, ME; Campbell, JL; Fisher, JW; McLanahan, ED | 1 |
| Braverman, LE; Pearce, EN | 1 |
| Ferguson, DC; Gilbert, ME; Sharlin, DS; Taylor, MA; Zoeller, RT | 1 |
| Colin, IM; Gérard, AC; Humblet, K; Poncin, S; Van Eeckoudt, S | 1 |
| Calil-Silveira, J; Nunes, MT; Serrano-Nascimento, C | 2 |
| Bestwick, JP; Braverman, LE; Burns, R; Dall'amico, D; He, X; Jooman, M; Lazarus, JH; Leung, AM; Maina, A; Parkes, AB; Pearce, EN; Smith, DF; Smyth, PP | 1 |
| Degitz, SJ; Hornung, MW; Korte, LM; Kosian, PA; Linnum, AL; Olson, JM; Tietge, JE | 1 |
| Padmanabhan, H | 1 |
| Fisher, JW; Kannan, K; Kunisue, T | 1 |
| Alevizaki, M; Alexiou, M; Braverman, LE; He, X; Ilias, I; Koukkou, E; Markou, KB; Pearce, EN | 1 |
| Braverman, LE; He, X; Jahreis, KA; Leung, AM; Pearce, EN; Roussilhes, A; Schuller, KE | 1 |
| Alwis, U; Blount, BC; Gold, EB; Kim, K; Lee, JS; O'Neill Rasor, M; Srivastav, A | 1 |
| Patiño, R; Sharma, P | 1 |
| Abraham, L; Hixon, JG; Proctor, DM; Suh, M | 1 |
| Chen, HX; Ding, MH; Li, YG; Liu, Q; Peng, KL | 1 |
| Charnley, G; Lewandowski, TA; Peterson, MK | 1 |
| Adams, EM; Buck, CL; Cresko, WA; Dillon, DM; Gardell, AM; Petersen, AM; Postlethwait, JH; von Hippel, FA | 1 |
| George, NI; Lumen, A | 1 |
| Ghassabian, A; Kohn, B; McMullen, J; Trasande, L | 1 |
| Chen, L; Huang, Y; Jiang, G; King, L; Li, W; Li, Y; Liang, X; Liu, L; Peng, X; Wang, P; Wang, Q; Xia, L | 1 |
| Fisher, J; Gilbert, M; Housand, C; Mattie, D; Moreau, M; Nong, A | 1 |
4 review(s) available for perchlorate and thyroxine
| Article | Year |
|---|---|
[Drug (amiodarone)-induced thyroid disease].
Topics: Amiodarone; Hormone Replacement Therapy; Humans; Hypothyroidism; Perchlorates; Prednisolone; Thyrotoxicosis; Thyroxine | 2005 |
Environmental pollutants and the thyroid.
Topics: Animals; Benzhydryl Compounds; Dioxins; Environmental Exposure; Environmental Pollutants; Female; Fetus; Halogenated Diphenyl Ethers; Humans; Hydrocarbons, Chlorinated; Iodide Peroxidase; Isoflavones; Lead; Liver; Nitrates; Perchlorates; Phenols; Polychlorinated Biphenyls; Pregnancy; Styrenes; Symporters; Thiocyanates; Thyroid Gland; Thyroxine; Triclosan | 2009 |
Amiodarone and thyroid dysfunction.
Topics: Amiodarone; Anti-Arrhythmia Agents; Antithyroid Agents; Continuity of Patient Care; Glucocorticoids; Hormone Replacement Therapy; Humans; Hypothyroidism; Iodine Radioisotopes; Methimazole; Perchlorates; Plasmapheresis; Risk Factors; Thyroid Gland; Thyroid Hormones; Thyroidectomy; Thyrotoxicosis; Thyroxine; Ultrasonography | 2010 |
The effects of perchlorate, nitrate, and thiocyanate on free thyroxine for potentially sensitive subpopulations of the 2001-2002 and 2007-2008 National Health and Nutrition Examination Surveys.
Topics: Environmental Pollutants; Female; Humans; Iodine; Male; Nitrates; Nutrition Surveys; Perchlorates; Pregnancy; Regression Analysis; Risk Factors; Thiocyanates; Thyroid Gland; Thyroxine; United States | 2014 |
1 trial(s) available for perchlorate and thyroxine
| Article | Year |
|---|---|
Effects of six months of daily low-dose perchlorate exposure on thyroid function in healthy volunteers.
Topics: Adult; Aged; Double-Blind Method; Female; Humans; Iodine; Iodine Radioisotopes; Male; Middle Aged; Perchlorates; Prospective Studies; Thyroglobulin; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine | 2006 |
34 other study(ies) available for perchlorate and thyroxine
| Article | Year |
|---|---|
[Effect of triiodothyronine & thyroxin on perchlorate goiter].
Topics: Goiter; Perchlorates; Thyroxine; Triiodothyronine | 1958 |
THYROTROPIN STIMULATION OF THYROXINE SYNTHESIS IN ISOLATED THYROID CELLS TREATED WITH PERCHLORATE.
Topics: Animals; Cattle; Chlorides; Diiodotyrosine; Metabolism; Perchlorates; Pharmacology; Pituitary Hormones, Anterior; Research; Thyroid Gland; Thyrotropin; Thyroxine | 1964 |
FURTHER STUDIES ON THE GOITROGENIC ACTION OF THYROXINE ADMINISTERED WITH PROPYLTHIOURACIL, METHIMAZOLE OR PERCHLORATE.
Topics: Antithyroid Agents; Body Weight; Iodine Isotopes; Methimazole; Organ Size; Perchlorates; Pharmacology; Pituitary Gland; Pituitary Hormones, Anterior; Propylthiouracil; Rats; Research; Thyroid Function Tests; Thyroid Gland; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Toxicology | 1965 |
Perchlorate affects thyroid function in eastern mosquitofish (Gambusia holbrooki) at environmentally relevant concentrations.
Topics: Animals; Biomarkers; Cyprinodontiformes; Dose-Response Relationship, Drug; Female; Perchlorates; Sensitivity and Specificity; Thyroid Gland; Thyroxine | 2005 |
Evaluation of gene expression endpoints in the context of a Xenopus laevis metamorphosis-based bioassay to detect thyroid hormone disruptors.
Topics: Animals; Antithyroid Agents; Biological Assay; Brain; DNA-Binding Proteins; Fresh Water; Gene Expression Regulation, Developmental; Hindlimb; Larva; Metamorphosis, Biological; Methimazole; Perchlorates; Propylthiouracil; Random Allocation; Receptors, Thyroid Hormone; Reverse Transcriptase Polymerase Chain Reaction; Thyroid Hormones; Thyroxine; Time Factors; Transcription Factors; Triiodothyronine; Xenopus laevis; Xenopus Proteins | 2006 |
The colloidal thyroxine (T4) ring as a novel biomarker of perchlorate exposure in the African clawed frog Xenopus laevis.
Topics: Animals; Biomarkers; Colloids; Environmental Monitoring; Female; Growth; Immunohistochemistry; Male; Perchlorates; Thyroid Gland; Thyroxine; Water Pollutants, Chemical; Xenopus laevis | 2006 |
Urinary perchlorate and thyroid hormone levels in adolescent and adult men and women living in the United States.
Topics: Adolescent; Adult; Age Factors; Environmental Monitoring; Female; Humans; Logistic Models; Male; Perchlorates; Socioeconomic Factors; Thyroid Hormones; Thyrotropin; Thyroxine; United States | 2006 |
Effects of larval-juvenile treatment with perchlorate and co-treatment with thyroxine on zebrafish sex ratios.
Topics: Age Factors; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Drug Interactions; Environmental Pollutants; Female; Gonads; Larva; Male; Perchlorates; Sex Differentiation; Sex Ratio; Statistics, Nonparametric; Thyroid Gland; Thyroxine; Zebrafish | 2007 |
Thyroid scintigraphy and perchlorate test after recombinant human TSH: a new tool for the differential diagnosis of congenital hypothyroidism during infancy.
Topics: Child; Child, Preschool; Congenital Hypothyroidism; Female; Humans; Infant; Iodides; Iodine Radioisotopes; Male; Perchlorates; Radionuclide Imaging; Recombinant Proteins; Thyroid Neoplasms; Thyrotropin; Thyroxine; Time Factors | 2007 |
Impact of smoking and thiocyanate on perchlorate and thyroid hormone associations in the 2001-2002 national health and nutrition examination survey.
Topics: Cotinine; Creatinine; Environmental Pollutants; Female; Humans; Iodine; Male; Nutrition Surveys; Perchlorates; Smoking; Thiocyanates; Thyrotropin; Thyroxine | 2007 |
Gestational exposure to high perchlorate concentrations in drinking water and neonatal thyroxine levels.
Topics: Adult; Blood Donors; Environmental Exposure; Female; Fetal Blood; Gestational Age; Humans; Infant, Newborn; Israel; Male; Perchlorates; Pregnancy; Thyroxine; Water Pollution, Chemical | 2007 |
Developmental exposure to perchlorate alters synaptic transmission in hippocampus of the adult rat.
Topics: Animals; Dose-Response Relationship, Drug; Female; Hippocampus; Male; Perchlorates; Pregnancy; Rats; Rats, Long-Evans; Synaptic Transmission; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine | 2008 |
Urinary perchlorate excretion does not predict thyroid function among pregnant women.
Topics: Chile; Female; Humans; Perchlorates; Predictive Value of Tests; Pregnancy; Regression Analysis; Thyroid Gland; Thyrotropin; Thyroxine | 2008 |
Sortilin is a putative postendocytic receptor of thyroglobulin.
Topics: Adaptor Proteins, Vesicular Transport; Animals; Chlorocebus aethiops; COS Cells; Endocytosis; Female; Haplorhini; Methimazole; Mice; Mice, Inbred C57BL; Perchlorates; Rats; Thyroglobulin; Thyroid Gland; Thyroxine | 2009 |
Thyroid histopathology assessments for the amphibian metamorphosis assay to detect thyroid-active substances.
Topics: Animals; Atrophy; Biological Assay; Histocytochemistry; Hyperplasia; Hypertrophy; Larva; Metamorphosis, Biological; Perchlorates; Thyroid Gland; Thyroxine; Xenobiotics; Xenopus laevis | 2009 |
Competitive inhibition of thyroidal uptake of dietary iodide by perchlorate does not describe perturbations in rat serum total T4 and TSH.
Topics: Animals; Biological Transport; Iodides; Male; Perchlorates; Rats; Thyroid Gland; Thyrotropin; Thyroxine; Water Pollutants, Chemical | 2009 |
The nature of the compensatory response to low thyroid hormone in the developing brain.
Topics: Animals; Antithyroid Agents; Brain; Female; Hypothyroidism; Iodide Peroxidase; Male; Methimazole; Monocarboxylic Acid Transporters; Neurogranin; Perchlorates; Propylthiouracil; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Thyrotropin; Thyroxine | 2010 |
Oxidative stress: a required condition for thyroid cell proliferation.
Topics: Acetylcysteine; Animals; Cell Nucleus; Cell Proliferation; Cyclin D1; Female; Goiter; Organ Size; Oxidative Stress; Perchlorates; Peroxiredoxins; Proliferating Cell Nuclear Antigen; Propylthiouracil; Prostaglandin D2; Rats; Rats, Wistar; Thyroid Gland; Thyroxine | 2010 |
Posttranscriptional regulation of sodium-iodide symporter mRNA expression in the rat thyroid gland by acute iodide administration.
Topics: Animals; Antithyroid Agents; Gene Expression Regulation; Iodides; Male; Methimazole; Perchlorates; Polyadenylation; Rats; Rats, Wistar; RNA, Messenger; Symporters; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine | 2010 |
Perchlorate and thiocyanate exposure and thyroid function in first-trimester pregnant women.
Topics: Adult; Autoantibodies; Chromatography, Ion Exchange; Cross-Sectional Studies; Enzyme-Linked Immunosorbent Assay; Female; Health Surveys; Humans; Immunoassay; Iodine; Italy; Mass Spectrometry; Maternal Exposure; Maternal-Fetal Exchange; Perchlorates; Pregnancy; Pregnancy Trimester, First; Prospective Studies; Regression Analysis; Smoking; Thiocyanates; Thyroid Function Tests; Thyroid Gland; Thyrotropin; Thyroxine; Wales | 2010 |
Inhibition of thyroid hormone release from cultured amphibian thyroid glands by methimazole, 6-propylthiouracil, and perchlorate.
Topics: Animals; Antithyroid Agents; Cattle; Coculture Techniques; Dose-Response Relationship, Drug; Female; Larva; Male; Methimazole; Organ Culture Techniques; Perchlorates; Pituitary Gland; Propylthiouracil; Thyroid Gland; Thyrotropin; Thyroxine; Xenopus laevis | 2010 |
Modulation of thyroid hormone concentrations in serum of rats coadministered with perchlorate and iodide-deficient diet.
Topics: Animals; Chromatography, Liquid; Environmental Pollutants; Iodides; Male; Perchlorates; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tandem Mass Spectrometry; Thyroxine | 2011 |
Iodide treatment acutely increases pendrin (SLC26A4) mRNA expression in the rat thyroid and the PCCl3 thyroid cell line by transcriptional mechanisms.
Topics: Animals; Antithyroid Agents; Cell Line; Cell Proliferation; Cell Survival; Chloride-Bicarbonate Antiporters; Dactinomycin; Iodides; Male; Methimazole; Perchlorates; Pituitary Gland; Protein Synthesis Inhibitors; Rats; Rats, Wistar; RNA, Messenger; Sulfate Transporters; Thyroid Gland; Thyrotropin; Thyroxine; Transcription, Genetic; Triiodothyronine | 2012 |
Perchlorate and thiocyanate exposure and thyroid function in first-trimester pregnant women from Greece.
Topics: Adult; Environmental Exposure; Female; Fetal Development; Greece; Humans; Iodides; Iodine; Perchlorates; Pregnancy; Pregnancy Trimester, First; Thiocyanates; Thyroid Function Tests; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine | 2012 |
Environmental perchlorate and thiocyanate exposures and infant serum thyroid function.
Topics: Adult; Boston; Breast Feeding; Cross-Sectional Studies; Environmental Exposure; Female; Humans; Infant; Iodine; Milk, Human; Perchlorates; Pregnancy; Prenatal Exposure Delayed Effects; Thiocyanates; Thyroid Function Tests; Thyroid Gland; Thyrotropin; Thyroxine; Young Adult | 2012 |
Thyroid hormones and thyroid disease in relation to perchlorate dose and residence near a superfund site.
Topics: Adult; California; Dose-Response Relationship, Drug; Drinking Water; Environmental Exposure; Female; Hazardous Waste Sites; Humans; Middle Aged; Perchlorates; Residence Characteristics; Thyroid Diseases; Thyroid Hormones; Thyrotropin; Thyroxine; Young Adult | 2013 |
Regulation of gonadal sex ratios and pubertal development by the thyroid endocrine system in zebrafish (Danio rerio).
Topics: Animals; Antithyroid Agents; Endocrine System; Female; Gonads; Male; Methimazole; Ovary; Perchlorates; Puberty; Sex Ratio; Testis; Thyroxine; Zebrafish | 2013 |
Dose-Response Relationship Between Orally Administered Ammonium Perchlorate and Urine Perchlorate Concentrations in Rats: Possible Biomarker to Quantify Environmental Ammonium Perchlorate Exposure on Thyroid Homeostasis.
Topics: Administration, Oral; Animals; Biomarkers; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Environmental Exposure; Homeostasis; Male; Mass Spectrometry; Perchlorates; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine | 2015 |
Iodine supplementation and drinking-water perchlorate mitigation.
Topics: Dietary Supplements; Dose-Response Relationship, Drug; Drinking Water; Female; Fetus; Humans; Iodine; Models, Biological; Perchlorates; Pregnancy; Thyroxine | 2015 |
Exogenous iodide ameliorates perchlorate-induced thyroid phenotypes in threespine stickleback.
Topics: Animals; Iodides; Perchlorates; Phenotype; Sexual Maturation; Smegmamorpha; Thyroid Dysgenesis; Thyroid Epithelial Cells; Thyroid Gland; Thyroxine | 2017 |
Evaluation of the risk of perchlorate exposure in a population of late-gestation pregnant women in the United States: Application of probabilistic biologically-based dose response modeling.
Topics: Adult; Drinking Water; Environmental Exposure; Female; Humans; Models, Statistical; Perchlorates; Pregnancy; Pregnancy Trimester, Third; Risk Assessment; Thyroxine; United States; Water Pollutants, Chemical; Water Supply | 2017 |
Identifying Subpopulations Vulnerable to the Thyroid-Blocking Effects of Perchlorate and Thiocyanate.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Child; Cross-Sectional Studies; Environmental Exposure; Female; Humans; Linear Models; Male; Middle Aged; Multivariate Analysis; Perchlorates; Retrospective Studies; Risk Assessment; Sex Factors; Thiocyanates; Thyroid Function Tests; Thyroid Gland; Thyrotropin; Thyroxine; Vulnerable Populations; Young Adult | 2017 |
Environmental exposure to perchlorate, nitrate and thiocyanate, and thyroid function in Chinese adults: A community-based cross-sectional study.
Topics: Bayes Theorem; China; Cross-Sectional Studies; East Asian People; Environmental Exposure; Female; Humans; Iodine; Male; Middle Aged; Nitrates; Perchlorates; Thiocyanates; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine | 2023 |
Towards translating in vitro measures of thyroid hormone system disruption to in vivo responses in the pregnant rat via a biologically based dose response (BBDR) model.
Topics: Animals; Drinking Water; Female; Perchlorates; Pregnancy; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Thyroid Hormones; Thyrotropin; Thyroxine | 2023 |