Page last updated: 2024-09-02

peramine and ergotamine

peramine has been researched along with ergotamine in 1 studies

*Ergotamine: A vasoconstrictor found in ergot of Central Europe. It is a serotonin agonist that has been used as an oxytocic agent and in the treatment of MIGRAINE DISORDERS. [MeSH]

*Ergotamine: A vasoconstrictor found in ergot of Central Europe. It is a serotonin agonist that has been used as an oxytocic agent and in the treatment of MIGRAINE DISORDERS. [MeSH]

Compound Research Comparison

Studies
(peramine)
Trials
(peramine)
Recent Studies (post-2010)
(peramine)
Studies
(ergotamine)
Trials
(ergotamine)
Recent Studies (post-2010) (ergotamine)
160112,352103103

Protein Interaction Comparison

ProteinTaxonomyperamine (IC50)ergotamine (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.056
Tyrosine-protein kinase LckHomo sapiens (human)6.499
Tyrosine-protein kinase FynHomo sapiens (human)3.16
Beta-2 adrenergic receptorHomo sapiens (human)2.761
Beta-1 adrenergic receptorHomo sapiens (human)4.142
Cytochrome P450 3A4Homo sapiens (human)1
Alpha-2A adrenergic receptorHomo sapiens (human)0.0021
D(2) dopamine receptorHomo sapiens (human)0.0043
Alpha-2B adrenergic receptorHomo sapiens (human)0.0038
Alpha-2C adrenergic receptorHomo sapiens (human)0.012
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.0008
D(1A) dopamine receptorHomo sapiens (human)1.728
Thromboxane-A synthase Homo sapiens (human)3.064
Alpha-1D adrenergic receptorHomo sapiens (human)0.049
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.0065
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.056
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.0008
D(3) dopamine receptorHomo sapiens (human)0.0043
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.0035
5-hydroxytryptamine receptor 6Homo sapiens (human)0.002

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Littler, RA; McLeay, LM; Poole, DP; Smith, BL1

Other Studies

1 other study(ies) available for peramine and ergotamine

ArticleYear
Effects and mechanisms of action of the ergopeptides ergotamine and ergovaline and the effects of peramine on reticulum motility of sheep.
    American journal of veterinary research, 2009, Volume: 70, Issue:2

    Topics: Analysis of Variance; Animals; Electromyography; Ergotamine; Ergotamines; Gastrointestinal Motility; Heterocyclic Compounds, 2-Ring; Male; Polyamines; Reticulum; Sheep

2009