Compounds > peptide elongation factor 2

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peptide elongation factor 2 and sordarin

peptide elongation factor 2 has been researched along with sordarin in 15 studies

Research

Studies (15)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	5 (33.33)	18.2507
2000's	6 (40.00)	29.6817
2010's	3 (20.00)	24.3611
2020's	1 (6.67)	2.80

Authors

Authors	Studies
Balkovec, J; Hsu, MJ; Justice, MC; Ku, T; Nielsen, J; Schmatz, D; Tse, B	1
Domínguez, JM; Martín, JJ	2
García-Bustos, JF; Gómez-Lorenzo, MG	1
Capa, L; García-Bustos, JF; Gómez de las Heras, F; Lavandera, JL; Mendoza, A	1
Domínguez, JM; Gómez-Lorenzo, MG; Martín, JJ	1
Anderson, J; Hsu, MJ; Justice, MC; Ku, T; Liberator, P; Nielsen, J; Schmatz, D; Shastry, M	1
Andersen, GR; Ballesta, JP; Beckmann, R; Frank, J; Gomez-Lorenzo, MG; Grassucci, RA; Jørgensen, R; Penczek, PA; Spahn, CM	1
Andersen, GR; Jørgensen, R; Merrill, AR; Nilsson, J; Prentice, GA; Teal, DJ; Yates, SP	1
Andersen, GR; Justice, M; Merrill, AR; Mosley, RT; Nielsen-Kahn, J; Shastry, M; Søe, R	1
Ballesta, JP; Botet, J; Remacha, M; Revuelta, JL; Rodríguez-Mateos, M	1
Chakraborty, B; Mukherjee, R; Sengupta, J	1
Chakraborty, B; Ghoshal, N; Payghan, PV; Sejpal, NV; Sengupta, J	1
Fleck, O; Knapp, K; Villahermosa, D	1
Ou, Z; Petrov, A	1

Other Studies

15 other study(ies) available for peptide elongation factor 2 and sordarin

Article	Year
Elongation factor 2 as a novel target for selective inhibition of fungal protein synthesis. The Journal of biological chemistry, 1998, Feb-06, Volume: 273, Issue:6 Topics: Antifungal Agents; Fungal Proteins; Indenes; Peptide Elongation Factor 2; Peptide Elongation Factors; Ribosomes; Saccharomyces cerevisiae	1998
Identification of elongation factor 2 as the essential protein targeted by sordarins in Candida albicans. Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:9 Topics: Amino Acid Sequence; Antifungal Agents; Candida albicans; Carrier Proteins; Indenes; Molecular Sequence Data; Peptide Elongation Factor 2; Peptide Elongation Factors; Protein Synthesis Inhibitors	1998
Ribosomal P-protein stalk function is targeted by sordarin antifungals. The Journal of biological chemistry, 1998, Sep-25, Volume: 273, Issue:39 Topics: Amino Acid Sequence; Animals; Antifungal Agents; Genetic Complementation Test; Humans; Indenes; Molecular Sequence Data; Mutation; Peptide Elongation Factor 2; Peptide Elongation Factors; Protozoan Proteins; Ribosomal Proteins; Saccharomyces cerevisiae; Sequence Homology, Amino Acid	1998
Translation elongation factor 2 is part of the target for a new family of antifungals. Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:10 Topics: Amino Acid Sequence; Antifungal Agents; Binding Sites; Drug Resistance, Microbial; Indenes; Molecular Sequence Data; Mutation; Peptide Elongation Factor 2; Peptide Elongation Factors	1998
Sordarin inhibits fungal protein synthesis by blocking translocation differently to fusidic acid. The Journal of biological chemistry, 1999, Aug-06, Volume: 274, Issue:32 Topics: Antifungal Agents; Candida albicans; Dose-Response Relationship, Drug; Fusidic Acid; GTP Phosphohydrolase-Linked Elongation Factors; Guanosine Triphosphate; Hydrolysis; Indenes; Models, Biological; Peptide Chain Elongation, Translational; Peptide Elongation Factor 2; Peptide Elongation Factors; Protein Synthesis Inhibitors; Puromycin; Ribosomes; Ricin	1999
Species-specific inhibition of fungal protein synthesis by sordarin: identification of a sordarin-specificity region in eukaryotic elongation factor 2. Microbiology (Reading, England), 2001, Volume: 147, Issue:Pt 2 Topics: Amino Acid Sequence; Antifungal Agents; Candida; Cloning, Molecular; Fungal Proteins; Humans; Indenes; Molecular Sequence Data; Peptide Elongation Factor 2; Protein Biosynthesis; Saccharomyces cerevisiae; Sequence Analysis, DNA; Species Specificity	2001
Identification of a putative sordarin binding site in Candida albicans elongation factor 2 by photoaffinity labeling. The Journal of biological chemistry, 2001, Aug-17, Volume: 276, Issue:33 Topics: Amino Acid Sequence; Antifungal Agents; Binding Sites; Candida albicans; Indenes; Molecular Sequence Data; Peptide Elongation Factor 2; Photoaffinity Labels	2001
Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation. The EMBO journal, 2004, Mar-10, Volume: 23, Issue:5 Topics: Antifungal Agents; Cryoelectron Microscopy; Crystallography, X-Ray; Indenes; Models, Molecular; Movement; Nucleic Acid Conformation; Peptide Elongation Factor 2; Protein Binding; Protein Structure, Quaternary; Protein Structure, Tertiary; Protein Subunits; Ribosomes; RNA Transport; RNA, Transfer; Saccharomyces cerevisiae	2004
Crystal structure of ADP-ribosylated ribosomal translocase from Saccharomyces cerevisiae. The Journal of biological chemistry, 2004, Oct-29, Volume: 279, Issue:44 Topics: Adenosine Diphosphate Ribose; Antifungal Agents; Binding Sites; Crystallization; Guanosine Diphosphate; Indenes; Peptide Elongation Factor 2; Protein Transport; Ribosomes; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins	2004
Sordarin derivatives induce a novel conformation of the yeast ribosome translocation factor eEF2. The Journal of biological chemistry, 2007, Jan-05, Volume: 282, Issue:1 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Crystallography, X-Ray; Fungal Proteins; Fusidic Acid; Indenes; Kinetics; Models, Molecular; Peptide Elongation Factor 2; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Ribosomes; RNA, Messenger; Saccharomyces cerevisiae	2007
A chemical genomic screen in Saccharomyces cerevisiae reveals a role for diphthamidation of translation elongation factor 2 in inhibition of protein synthesis by sordarin. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:5 Topics: Electrophoresis, Polyacrylamide Gel; Genomics; Indenes; Mutation; Peptide Elongation Factor 2; Protein Biosynthesis; Protein Synthesis Inhibitors; Saccharomyces cerevisiae	2008
Structural insights into the mechanism of translational inhibition by the fungicide sordarin. Journal of computer-aided molecular design, 2013, Volume: 27, Issue:2 Topics: Amino Acid Sequence; Antifungal Agents; Crystallography, X-Ray; Humans; Indenes; Molecular Sequence Data; Peptide Chain Elongation, Translational; Peptide Elongation Factor 2; Protein Conformation; Protein Synthesis Inhibitors; Ribosomes; Saccharomyces cerevisiae; Sequence Homology, Amino Acid	2013
Structure-based designing of sordarin derivative as potential fungicide with pan-fungal activity. Journal of molecular graphics & modelling, 2016, Volume: 66 Topics: Amino Acid Sequence; Antifungal Agents; Binding Sites; Candida parapsilosis; Drug Design; Fungal Proteins; Fungicides, Industrial; Humans; Indenes; Peptide Elongation Factor 2	2016
A mutated dph3 gene causes sensitivity of Schizosaccharomyces pombe cells to cytotoxic agents. Current genetics, 2017, Volume: 63, Issue:6 Topics: Codon, Initiator; Cytotoxins; Gene Expression Regulation, Fungal; Genetic Engineering; Genetic Loci; Genetic Markers; Histidine; Hydroxyurea; Indenes; Methyl Methanesulfonate; Mutation; MutS Homolog 3 Protein; Peptide Elongation Factor 2; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Schizosaccharomyces; Schizosaccharomyces pombe Proteins	2017
Sordarin bound eEF2 unlocks spontaneous forward and reverse translocation on CrPV IRES. Nucleic acids research, 2023, 07-21, Volume: 51, Issue:13 Topics: Guanosine Triphosphate; Internal Ribosome Entry Sites; Peptide Elongation Factor 2; Protein Biosynthesis; RNA, Viral	2023