Page last updated: 2024-08-26

peptide elongation factor 2 and sirolimus

peptide elongation factor 2 has been researched along with sirolimus in 12 studies

Research

Studies (12)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (8.33)	18.2507
2000's	9 (75.00)	29.6817
2010's	2 (16.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Gelfand, EW; Kohno, K; Nairn, AC; Patel, HR; Takase, K; Terada, N	1
Proud, CG; Wang, L; Wang, X	1
Brautigan, D; Everett, AD; Nairn, AC; Stoops, TD	1
Sans, MD; Williams, JA; Xie, Q	1
Carroll, M; Fan, X; Sossin, WS; Warren, O	1
Avruch, J; Lenz, G	1
Gu, J; Nadler, JL; Nairn, AC; Peng, X; Yeshao, W	1
Hayashi, AA; Proud, CG	1
Dhanani, S; Dreyer, HC; Drummond, MJ; Fry, CS; Glynn, EL; Rasmussen, BB; Timmerman, KL; Volpi, E	1
Dyck, JR; Ikeda, Y; Pimentel, DR; Sam, F; Sato, K; Shaw, RJ; Walsh, K	1
Husain, M; Kasinath, BS; Malhotra, A; Rehman, S; Singhal, PC; Yadav, A	1
Adrian, L; Arend, M; Brinkmann, U; Hawer, H; Mayer, K; Schaffrath, R; Ütkür, K	1

Trials

1 trial(s) available for peptide elongation factor 2 and sirolimus

Article	Year
Rapamycin administration in humans blocks the contraction-induced increase in skeletal muscle protein synthesis. The Journal of physiology, 2009, Apr-01, Volume: 587, Issue:Pt 7 Topics: Administration, Oral; Adult; Amino Acids; Exercise; Humans; Hydrocortisone; Insulin; Intracellular Signaling Peptides and Proteins; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle Contraction; Muscle Proteins; Muscle, Skeletal; Peptide Elongation Factor 2; Phosphorylation; Protein Biosynthesis; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Ribosomal Protein S6 Kinases; Signal Transduction; Sirolimus; Time Factors; TOR Serine-Threonine Kinases	2009

Article

Year

Rapamycin administration in humans blocks the contraction-induced increase in skeletal muscle protein synthesis.

The Journal of physiology, 2009, Apr-01, Volume: 587, Issue:Pt 7

Topics: Administration, Oral; Adult; Amino Acids; Exercise; Humans; Hydrocortisone; Insulin; Intracellular Signaling Peptides and Proteins; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle Contraction; Muscle Proteins; Muscle, Skeletal; Peptide Elongation Factor 2; Phosphorylation; Protein Biosynthesis; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Ribosomal Protein S6 Kinases; Signal Transduction; Sirolimus; Time Factors; TOR Serine-Threonine Kinases

2009

Other Studies

11 other study(ies) available for peptide elongation factor 2 and sirolimus

Article	Year
Rapamycin selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins. Proceedings of the National Academy of Sciences of the United States of America, 1994, Nov-22, Volume: 91, Issue:24 Topics: Base Sequence; Cell Division; Cell Line; Humans; Molecular Sequence Data; Oligodeoxyribonucleotides; Peptide Elongation Factor 2; Peptide Elongation Factors; Polyenes; Protein Biosynthesis; Protein Serine-Threonine Kinases; Ribosomal Protein S6 Kinases; Ribosomal Proteins; Sirolimus	1994
Activation of mRNA translation in rat cardiac myocytes by insulin involves multiple rapamycin-sensitive steps. American journal of physiology. Heart and circulatory physiology, 2000, Volume: 278, Issue:4 Topics: Age Factors; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Cells, Cultured; Chromones; Enzyme Activation; Enzyme Inhibitors; Eukaryotic Initiation Factor-4E; Flavonoids; Gene Expression Regulation, Enzymologic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Heart Ventricles; Hypoglycemic Agents; Immunosuppressive Agents; Insulin; Intracellular Signaling Peptides and Proteins; Methionine; Morpholines; Muscle Fibers, Skeletal; Myocardium; Peptide Elongation Factor 2; Peptide Initiation Factors; Phenylalanine; Phosphoproteins; Phosphorylation; Protein Biosynthesis; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Ribosomal Protein S6 Kinases; RNA, Messenger; Signal Transduction; Sirolimus; Sulfur Radioisotopes; Tritium	2000
Angiotensin II regulates phosphorylation of translation elongation factor-2 in cardiac myocytes. American journal of physiology. Heart and circulatory physiology, 2001, Volume: 281, Issue:1 Topics: Angiotensin II; Animals; Cells, Cultured; Chromones; Enzyme Inhibitors; Mitogen-Activated Protein Kinases; Morpholines; Myocardium; Peptide Elongation Factor 2; Phosphoprotein Phosphatases; Phosphorylation; Protein Biosynthesis; Protein Phosphatase 2; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Signal Transduction; Sirolimus	2001
Regulation of translation elongation and phosphorylation of eEF2 in rat pancreatic acini. Biochemical and biophysical research communications, 2004, Jun-18, Volume: 319, Issue:1 Topics: Animals; Bombesin; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cholecystokinin; Cyclic AMP; Dose-Response Relationship, Drug; Elongation Factor 2 Kinase; Enzyme Inhibitors; Flavonoids; Imidazoles; Marine Toxins; Oxazoles; Pancreas; Peptide Elongation Factor 2; Peptides; Phosphorylation; Protein Biosynthesis; Pyridines; Rats; Signal Transduction; Sirolimus; Time Factors	2004
5-HT stimulates eEF2 dephosphorylation in a rapamycin-sensitive manner in Aplysia neurites. Journal of neurochemistry, 2004, Volume: 90, Issue:6 Topics: Amino Acid Sequence; Animals; Aplysia; Axotomy; Base Sequence; Blotting, Western; Cells, Cultured; Cloning, Molecular; Drug Interactions; Enzyme Inhibitors; Fluorescence Recovery After Photobleaching; Gene Expression Regulation; Immunohistochemistry; Models, Neurological; Neurites; Neurons; Peptide Elongation Factor 2; Phosphorylation; Potassium Chloride; Serotonin; Sirolimus; Synaptosomes; Tacrolimus Binding Protein 1A; Threonine; Time Factors	2004
Glutamatergic regulation of the p70S6 kinase in primary mouse neurons. The Journal of biological chemistry, 2005, Nov-18, Volume: 280, Issue:46 Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Animals; Bicuculline; Calcium; Calcium Channels; Calcium Channels, L-Type; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Dopamine; gamma-Aminobutyric Acid; Glutamine; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neurons; Norepinephrine; Peptide Elongation Factor 2; Phosphatidylinositol 3-Kinases; Phosphorylation; Potassium Channels; Protein Kinases; Ribosomal Protein S6 Kinases, 70-kDa; RNA, Messenger; Signal Transduction; Sirolimus; Synapses; Time Factors; TOR Serine-Threonine Kinases	2005
Elevated glucose activates protein synthesis in cultured cardiac myocytes. Metabolism: clinical and experimental, 2005, Volume: 54, Issue:11 Topics: Animals; Antibiotics, Antineoplastic; Cells, Cultured; Glucose; Leucine; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocytes, Cardiac; Peptide Elongation Factor 2; Phosphorylation; Protein Biosynthesis; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sirolimus	2005
The rapid activation of protein synthesis by growth hormone requires signaling through mTOR. American journal of physiology. Endocrinology and metabolism, 2007, Volume: 292, Issue:6 Topics: Animals; Carrier Proteins; Cell Line, Tumor; Eukaryotic Initiation Factor-4E; Eukaryotic Initiation Factor-4F; Eukaryotic Initiation Factor-4G; Growth Hormone; Intracellular Signaling Peptides and Proteins; Kinetics; Peptide Elongation Factor 2; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Biosynthesis; Rats; Recombinant Proteins; Ribosomal Protein S6; Signal Transduction; Sirolimus; Time Factors; Transcription Factors	2007
Cardiac-specific deletion of LKB1 leads to hypertrophy and dysfunction. The Journal of biological chemistry, 2009, Dec-18, Volume: 284, Issue:51 Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Antibiotics, Antineoplastic; Atrial Fibrillation; Carrier Proteins; Collagen Type I; Collagen Type II; Fibrosis; Gene Expression Regulation; Heart Atria; Hypertrophy, Left Ventricular; Mice; Mice, Knockout; Myocardium; Organ Specificity; Peptide Elongation Factor 2; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein Kinases; Protein Serine-Threonine Kinases; Ribosomal Protein S6 Kinases, 70-kDa; RNA, Messenger; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases	2009
HIV-1 promotes renal tubular epithelial cell protein synthesis: role of mTOR pathway. PloS one, 2012, Volume: 7, Issue:1 Topics: AIDS-Associated Nephropathy; Animals; DNA; Enzyme Activation; Epithelial Cells; Fibronectins; HIV-1; Humans; Intracellular Space; Kidney Tubules; Laminin; Mice; Models, Biological; Peptide Elongation Factor 2; Phosphorylation; Pol1 Transcription Initiation Complex Proteins; Protein Biosynthesis; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases	2012
Importance of diphthamide modified EF2 for translational accuracy and competitive cell growth in yeast. PloS one, 2018, Volume: 13, Issue:10 Topics: Amino Acid Substitution; Anisomycin; Caffeine; Cell Division; Cinnamates; Diphtheria Toxin; Gene Deletion; Gene Expression Regulation, Fungal; Histidine; Hygromycin B; Methyltransferases; Peptide Elongation Factor 1; Peptide Elongation Factor 2; Phenotype; Protein Biosynthesis; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sirolimus	2018