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peptide elongation factor 2 and adenosine diphosphate ribose

peptide elongation factor 2 has been researched along with adenosine diphosphate ribose in 96 studies

Research

Studies (96)

TimeframeStudies, this research(%)All Research%
pre-199046 (47.92)18.7374
1990's28 (29.17)18.2507
2000's18 (18.75)29.6817
2010's3 (3.13)24.3611
2020's1 (1.04)2.80

Authors

AuthorsStudies
Fendrick, JL; Iglewski, WJ; Moehring, JM; Moehring, TJ1
Bierer, L; Gotlib, J; Haroutunian, V; Johnson, G; Merril, C; Nairn, AC; Wallace, W1
Bastrop, R; Junghahn, I; Jürss, K1
Bonavida, B; Morimoto, H1
Collier, RJ; Wilson, BA1
Brigotti, M; Montanaro, L; Sperti, S; Zamboni, M1
Akiyoshi, DE; Arrigo, DA; Bacha, P; Genbauffe, FS; Nichols, JC; Rhoad, AE; Shaw, JP; Sullivan, B; Thomas, J1
Collier, RJ; Reich, KA; Weinstein, BR; Wilson, BA1
Clark, BF; Derventzi, A; Rattan, SI; Riis, B1
Davydova, EK; Ovchinnikov, LP1
Nilsson, L; Nygård, O3
Lavergne, JP; Marzouki, A; Reboud, AM; Reboud, JP2
Davydova, EK1
Chen, MS; Hwang, J1
Nitzan, Y; Parizade, P; Salzberg, S1
Carson, DA; Wasson, DB; Yamanaka, H1
Fendrick, JL; Iglewski, WJ1
Clark, BF; Rattan, SI; Riis, B1
Kigoshi, T; Morimoto, S; Uchida, K1
Kohno, K; Omura, F; Uchida, T1
Chen, HC; Guroff, G; Hama, T; Koizumi, S; Ryazanov, A1
Kohno, K; Uchida, T1
Cavallius, J; Clark, BF; Rattan, SI; Riis, B1
Balestrieri, C; Giovane, A; Quagliuolo, L; Servillo, L4
Bodley, JW; Chen, JY1
Carson, DA; Kajander, EO; Yamanaka, H1
Bermek, E; Nurten, R; Ozdemirli, M; Sayhan, O1
Galloway, DR; Hsu, LY; Wozniak, DJ1
Fanick, W; Hilz, H; Koch, R; Meyer, T1
Saruyama, H; Sasaki, S1
Nairn, AC; Palfrey, HC1
Abraham, AK; Burns, G; Vedeler, A1
Kohno, K; Mekada, E; Okada, Y; Uchida, T1
Hudson, TH; Neville, DM1
Gehrmann, R; Henschen, A; Klink, F1
Clowes, RC; Draper, RK; Jordan, EM; Mozola, MA; Wilson, RB1
Davydova, EK; Ovchinnikov, LP; Sitikov, AS1
Bezlepkina, TA; Davydova, EK; Ovchinnikov, LP; Sitikov, AS; Spirin, AS1
Bodley, JW; Oppenheimer, NJ1
Iglewski, WJ; Lee, H1
Bodley, JW; Dunlop, PC; VanNess, BG1
Adolph, KW; Bodley, JW; Dunlop, PC; Pappenheimer, AM1
Kaneda, Y; Mekada, E; Nakanishi, M; Okada, Y; Uchida, T1
Uchida, T1
Aktar, NB; Bermek, E; Nurten, R1
Bodley, JW; Howard, JB; Van Ness, BG2
Chinali, G; Ferrini, U; Sacchi, A1
Delpino, A; Ferrini, U; Mattei, E1
Moynihan, MR; Pappenheimer, AM1
Gupta, RS1
Barrowclough, B; Bodley, JW; Van Ness, BG1
Bocchini, V; Masullo, M; Raimo, G1
Klink, F; Siegmund, KD1
Iglewski, WJ1
Blanke, SR; Collier, RJ; Covacci, A; Huang, K; Papini, E; Wilson, BA1
Chung, CH; Ha, DB; Jeon, YJ; Kang, MS; Kim, HS1
Snyder, SH; Zhang, J1
Harashima, S; Kimata, Y; Kohno, K1
Brinkmann, E; Brinkmann, U; Gallo, M; Pastan, I; Scherf, U1
Benson, EL; Blanke, SR; Collier, RJ; Milne, JC1
Ayala, A; Bougria, M; Machado, A; Parrado, J1
Bocchini, V; Masullo, M; Raimo, G; Scarano, G1
Zhang, J1
Horiguchi, Y; Masuda, M1
Bektaş, M; Bermek, E; Nurten, R; Sayers, Z1
Brenner, M; DeGracia, DJ; Dever, TE; Frerichs, KU; Hallenbeck, JM; Krause, GS; Marrone, L; Smith, CB1
Albeniz, I; Bermek, E; Nurten, R1
Galicka, A; Gindzieński, A; Sredzińska, K1
Friedrich, I; Jäger, D; Müller-Werdan, U; Pönicke, K; Redpath, NT; Seliger, C; Silber, RE; Werdan, K1
He, WJ; Liu, WY; Ruan, KC; Tang, S; Xu, H1
Christophersen, CT; Karlsen, J; Nielsen, MO; Riis, B1
Armstrong, S; Merrill, AR1
Parikh, SL; Schramm, VL1
Bektaş, M; Bermek, E; Günçer, B; Güven, C; Nurten, R1
Andersen, GR; Jørgensen, R; Merrill, AR; Nilsson, J; Prentice, GA; Teal, DJ; Yates, SP1
Akçakaya, H; Aroymak, A; Bektaş, M; Bermek, E; Nurten, R1
Chang, MP; Lee, JW; Nakamura, LT; Wisnieski, BJ1
FitzGerald, DJ; Pastrana, DV1
Kaufmann, SH; Kim, C; Merrill, AR; Slavinskaya, Z1
Iwamoto, R; Kageyama, T; Mekada, E; Miyamoto, S; Mizushima, H; Ohishi, M1
Bektaş, M; Ergen, K; Gökçe, S; Nurten, R1
Bachran, C; Bachran, D; Fuchs, H; Sutherland, M1
Barbieri, JT; Deng, Q1
Du, J; Jiang, H; Lin, H1
Brummelkamp, TR; Carette, JE; Cochran, BH; Godarova, A; Guimaraes, CP; Kotecki, M; Park, AS; Ploegh, HL; Spooner, E; Varadarajan, M; Wuethrich, I1
Gupta, PK; Leppla, SH; Liu, S1
Argüelles, S; Ayala, A; Camandola, S; Cutler, RG; Hutchison, ER; Mattson, MP1
Cai, Y; Chen, KC; Xie, H1
Eriksson, LA; Gholami, A; Mahdizadeh, SJ; Minai-Tehrani, D; Saenz-Mendez, P1

Reviews

5 review(s) available for peptide elongation factor 2 and adenosine diphosphate ribose

ArticleYear
Diphtheria toxin and Pseudomonas aeruginosa exotoxin A: active-site structure and enzymic mechanism.
    Current topics in microbiology and immunology, 1992, Volume: 175

    Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Amino Acid Sequence; Bacterial Toxins; Binding Sites; Catalysis; Corynebacterium diphtheriae; Diphtheria Toxin; Exotoxins; Models, Molecular; Molecular Sequence Data; NAD; Peptide Elongation Factor 2; Peptide Elongation Factors; Poly(ADP-ribose) Polymerases; Protein Conformation; Pseudomonas aeruginosa; Pseudomonas aeruginosa Exotoxin A; Structure-Activity Relationship; Virulence Factors

1992
Diphtheria toxin.
    Pharmacology & therapeutics, 1982, Volume: 19, Issue:1

    Topics: Adenosine Diphosphate Ribose; Animals; Cell Line; Cell Membrane; Cross Reactions; Cytosol; Diphtheria Toxin; Humans; Kinetics; Peptide Elongation Factor 2; Peptide Elongation Factors; Receptors, Drug

1982
Cellular ADP-ribosylation of elongation factor 2.
    Molecular and cellular biochemistry, 1994, Volume: 138, Issue:1-2

    Topics: Adenosine Diphosphate Ribose; Animals; Cells; Models, Biological; Peptide Elongation Factor 2; Peptide Elongation Factors

1994
[The GTP-binding proteins as targets for bacterial toxins].
    Nihon saikingaku zasshi. Japanese journal of bacteriology, 1997, Volume: 52, Issue:4

    Topics: Adenosine Diphosphate Ribose; Bacterial Toxins; Glycosylation; GTP-Binding Proteins; Molecular Weight; Peptide Elongation Factor 2; Peptide Elongation Factors; Signal Transduction

1997
Molecular mechanisms of the cytotoxicity of ADP-ribosylating toxins.
    Annual review of microbiology, 2008, Volume: 62

    Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Bacterial Toxins; Cytotoxins; Diphtheria Toxin; Exotoxins; GTPase-Activating Proteins; Humans; Leukocidins; Models, Biological; Models, Molecular; Peptide Elongation Factor 2; Pseudomonas aeruginosa Exotoxin A; Virulence Factors

2008

Other Studies

91 other study(ies) available for peptide elongation factor 2 and adenosine diphosphate ribose

ArticleYear
Characterization of the endogenous ADP-ribosylation of wild-type and mutant elongation factor 2 in eukaryotic cells.
    European journal of biochemistry, 1992, Apr-01, Volume: 205, Issue:1

    Topics: Adenosine Diphosphate Ribose; Animals; Cell Line; Cell Transformation, Viral; CHO Cells; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cricetinae; Diphtheria Toxin; Electrophoresis, Polyacrylamide Gel; Histidine; Kinetics; Mutation; Peptide Elongation Factor 2; Peptide Elongation Factors; Phosphoric Diester Hydrolases; Poly(ADP-ribose) Polymerases; Precipitin Tests; Snake Venoms; Trypsin

1992
Increased phosphorylation of elongation factor 2 in Alzheimer's disease.
    Brain research. Molecular brain research, 1992, Volume: 15, Issue:3-4

    Topics: Adenosine Diphosphate Ribose; Alzheimer Disease; Blotting, Western; Electrophoresis, Gel, Two-Dimensional; Humans; Nerve Tissue Proteins; Peptide Elongation Factor 2; Peptide Elongation Factors; Phosphoproteins; Phosphorylation; Polyribosomes; Protein Biosynthesis; Reticulocytes

1992
The role of elongation factors in protein synthesis rate variation in white teleost muscle.
    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 1992, Volume: 162, Issue:4

    Topics: Adenosine Diphosphate Ribose; Animals; Carps; Cytosol; Fishes; In Vitro Techniques; Liver; Muscle Proteins; Muscles; Peptide Elongation Factor 1; Peptide Elongation Factor 2; Peptide Elongation Factors; Rats; Rats, Inbred Strains; Starvation; Trout

1992
Diphtheria toxin- and Pseudomonas A toxin-mediated apoptosis. ADP ribosylation of elongation factor-2 is required for DNA fragmentation and cell lysis and synergy with tumor necrosis factor-alpha.
    Journal of immunology (Baltimore, Md. : 1950), 1992, Sep-15, Volume: 149, Issue:6

    Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Bacterial Toxins; Cell Death; Diphtheria Toxin; DNA Damage; Drug Synergism; Exotoxins; Humans; In Vitro Techniques; Peptide Elongation Factor 2; Peptide Elongation Factors; Pseudomonas aeruginosa Exotoxin A; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Virulence Factors

1992
Elongation factor 2 from Artemia salina embryos and its affinity for ribosomes.
    European journal of biochemistry, 1991, Aug-15, Volume: 200, Issue:1

    Topics: Adenosine Diphosphate Ribose; Animals; Artemia; Calcium-Calmodulin-Dependent Protein Kinases; Electrophoresis, Polyacrylamide Gel; Elongation Factor 2 Kinase; Gastrula; Isoelectric Point; Peptide Elongation Factor 2; Peptide Elongation Factors; Phosphorylation; Poly(ADP-ribose) Polymerases; Protein Kinases; Rats; Ribosomes; Sepharose

1991
Cytotoxic properties of DAB486EGF and DAB389EGF, epidermal growth factor (EGF) receptor-targeted fusion toxins.
    The Journal of biological chemistry, 1991, Nov-05, Volume: 266, Issue:31

    Topics: Adenosine Diphosphate Ribose; Cell Death; Diphtheria Toxin; Epidermal Growth Factor; ErbB Receptors; Escherichia coli; Genetic Engineering; Humans; In Vitro Techniques; Peptide Elongation Factor 2; Peptide Elongation Factors; Plasmids; Recombinant Fusion Proteins

1991
Active-site mutations of diphtheria toxin: effects of replacing glutamic acid-148 with aspartic acid, glutamine, or serine.
    Biochemistry, 1990, Sep-18, Volume: 29, Issue:37

    Topics: Adenosine Diphosphate Ribose; Affinity Labels; Aspartic Acid; Base Sequence; Binding Sites; Diphtheria Toxin; Glutamates; Glutamic Acid; Glutamine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Peptide Elongation Factor 2; Peptide Elongation Factors; Serine; Substrate Specificity

1990
Reduced levels of ADP-ribosylatable elongation factor-2 in aged and SV40-transformed human cell cultures.
    FEBS letters, 1990, Jun-18, Volume: 266, Issue:1-2

    Topics: Adenosine Diphosphate Ribose; Cell Cycle; Cell Survival; Cell Transformation, Viral; Cells, Cultured; Humans; In Vitro Techniques; Peptide Chain Elongation, Translational; Peptide Elongation Factor 2; Peptide Elongation Factors; Simian virus 40

1990
ADP-ribosylated elongation factor 2 (ADP-ribosyl-EF-2) is unable to promote translocation within the ribosome.
    FEBS letters, 1990, Feb-26, Volume: 261, Issue:2

    Topics: Adenosine Diphosphate Ribose; Animals; Binding, Competitive; Biological Transport; Diphtheria Toxin; Guanosine Triphosphate; Peptide Elongation Factor 2; Peptide Elongation Factors; Poly U; Puromycin; Rabbits; Ribosomes; RNA, Transfer, Phe

1990
Kinetic determination of the effects of ADP-ribosylation on the interaction of eukaryotic elongation factor 2 with ribosomes.
    The Journal of biological chemistry, 1990, Apr-15, Volume: 265, Issue:11

    Topics: Adenosine Diphosphate Ribose; Animals; Carcinoma, Ehrlich Tumor; Diphtheria Toxin; Guanosine Triphosphate; Kinetics; Mice; NAD; Peptide Elongation Factor 2; Peptide Elongation Factors; Phosphoproteins; Ribosomes; Ricin

1990
Modification of the reactivity of three amino-acid residues in elongation factor 2 during its binding to ribosomes and translocation.
    Biochimica et biophysica acta, 1990, Apr-06, Volume: 1048, Issue:2-3

    Topics: Adenosine Diphosphate Ribose; Animals; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Liver; Mutation; NAD; Peptide Elongation Factor 2; Peptide Elongation Factors; Peptide Mapping; Phosphoproteins; Phosphorylation; Protein Binding; Rats; Ribosomes; Trypsin

1990
[The ADP-ribosylation site and RNA-binding center are located in different regions of the elongation factor EF-2].
    Doklady Akademii nauk SSSR, 1986, Volume: 289, Issue:2

    Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Binding Sites; Histidine; Nucleoside Diphosphate Sugars; Peptide Elongation Factor 2; Peptide Elongation Factors; Rabbits; RNA

1986
Structure and function relationship of Pseudomonas exotoxin A. An immunochemical study.
    The Journal of biological chemistry, 1989, Feb-05, Volume: 264, Issue:4

    Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Antigen-Antibody Complex; Bacterial Toxins; Epitopes; Exotoxins; Immune Sera; Immunoblotting; Models, Molecular; Peptide Elongation Factor 2; Peptide Elongation Factors; Plasmids; Protein Conformation; Pseudomonas aeruginosa; Pseudomonas aeruginosa Exotoxin A; Rabbits; Vaccination; Virulence Factors

1989
Combined treatment with Pseudomonas aeruginosa toxin and interferon on mouse and human cells.
    Toxicon : official journal of the International Society on Toxinology, 1989, Volume: 27, Issue:8

    Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Antiviral Agents; Bacterial Toxins; Cell Line; Cell Line, Transformed; Exotoxins; Humans; Interferon Type I; Mice; Peptide Elongation Factor 2; Peptide Elongation Factors; Protein Synthesis Inhibitors; Pseudomonas aeruginosa Exotoxin A; RNA-Directed DNA Polymerase; Species Specificity; Virulence Factors

1989
Utilization of 2'-deoxynad for ADP-ribose transfer reactions.
    Advances in experimental medicine and biology, 1989, Volume: 253B

    Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Diphtheria Toxin; Humans; NAD; Peptide Elongation Factor 2; Peptide Elongation Factors; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases

1989
Endogenous ADP-ribosylation of elongation factor 2 in polyoma virus-transformed baby hamster kidney cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1989, Volume: 86, Issue:2

    Topics: Adenosine Diphosphate Ribose; Animals; Cell Line, Transformed; Chromatography, High Pressure Liquid; Culture Media; Kinetics; Peptide Elongation Factor 2; Peptide Elongation Factors; Peptides; Polyomavirus; Precipitin Tests; Proteins

1989
Estimating the amounts of ADP-ribosylatable active elongation factor-2 in mammalian cell-free extracts.
    Journal of biochemical and biophysical methods, 1989, Volume: 19, Issue:4

    Topics: Adenosine Diphosphate Ribose; Animals; Carbon Radioisotopes; Diphtheria Toxin; HeLa Cells; Humans; Kinetics; Liver; NAD; Peptide Elongation Factor 2; Peptide Elongation Factors; Phosphoproteins; Radioisotope Dilution Technique; Rats

1989
Elongation factor 2 as the major substrate for Ca2+/calmodulin-dependent protein kinase in rat adrenal glomerulosa cells.
    Journal of steroid biochemistry, 1989, Volume: 32, Issue:3

    Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Calmodulin; Cytosol; Electrophoresis, Polyacrylamide Gel; Female; Isoelectric Point; Molecular Weight; Peptide Elongation Factor 2; Peptide Elongation Factors; Phosphorylation; Pimozide; Protein Kinases; Rats; Rats, Inbred Strains; Zona Glomerulosa

1989
The histidine residue of codon 715 is essential for function of elongation factor 2.
    European journal of biochemistry, 1989, Mar-01, Volume: 180, Issue:1

    Topics: Adenosine Diphosphate Ribose; Animals; Codon; DNA; Drug Resistance; Histidine; L Cells; Mice; Mutation; Peptide Elongation Factor 2; Peptide Elongation Factors; Promoter Regions, Genetic; Protein Biosynthesis; RNA, Messenger; Toxins, Biological

1989
Identification of Nsp100 as elongation factor 2 (EF-2).
    FEBS letters, 1989, Aug-14, Volume: 253, Issue:1-2

    Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Molecular Sequence Data; Nerve Tissue Proteins; Peptide Elongation Factor 2; Peptide Elongation Factors; Pheochromocytoma; Phosphoproteins; Phosphorylation; Rats; Tumor Cells, Cultured

1989
Heterogeneity of native rat liver elongation factor 2.
    FEBS letters, 1989, Sep-11, Volume: 255, Issue:1

    Topics: Adenosine Diphosphate Ribose; Animals; Electrophoresis, Polyacrylamide Gel; Isoelectric Focusing; Microsomes, Liver; Molecular Structure; Peptide Elongation Factor 2; Peptide Elongation Factors; Phosphorylation; Rats

1989
Highly frequent single amino acid substitution in mammalian elongation factor 2 (EF-2) results in expression of resistance to EF-2-ADP-ribosylating toxins.
    The Journal of biological chemistry, 1987, Sep-05, Volume: 262, Issue:25

    Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Bacterial Toxins; Cell Line; Cloning, Molecular; Cricetinae; Diphtheria Toxin; DNA; Drug Resistance; Exotoxins; Gene Expression Regulation; Histidine; Peptide Elongation Factor 2; Peptide Elongation Factors; Plasmids; Polymorphism, Restriction Fragment Length; Protein Processing, Post-Translational; Pseudomonas aeruginosa Exotoxin A; Virulence Factors

1987
ADP-ribosylatable content of elongation factor-2 changes during cell cycle of normal and cancerous human cells.
    Biochemical and biophysical research communications, 1989, Mar-31, Volume: 159, Issue:3

    Topics: Adenosine Diphosphate Ribose; Cell Cycle; Cell Line; Cell-Free System; Cells, Cultured; Diphtheria Toxin; Fibroblasts; Humans; Kinetics; Peptide Elongation Factor 2; Peptide Elongation Factors; Skin; Tumor Cells, Cultured

1989
1-N6-Etheno-ADP-ribosylation of elongation factor-2 by diphtheria toxin.
    FEBS letters, 1985, Oct-28, Volume: 191, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Diphosphate Ribose; Chromatography; Diphtheria Toxin; Female; Humans; Kinetics; NAD; Nucleoside Diphosphate Sugars; Peptide Elongation Factor 2; Peptide Elongation Factors; Peptide Fragments; Phosphoric Diester Hydrolases; Placenta; Pregnancy; Spectrometry, Fluorescence

1985
Biosynthesis of diphthamide in Saccharomyces cerevisiae. Partial purification and characterization of a specific S-adenosylmethionine:elongation factor 2 methyltransferase.
    The Journal of biological chemistry, 1988, Aug-25, Volume: 263, Issue:24

    Topics: Adenosine Diphosphate Ribose; Chromatography, High Pressure Liquid; Diphtheria Toxin; Drug Resistance; Histidine; Kinetics; Methylation; Methyltransferases; Mutation; Peptide Elongation Factor 2; Peptide Elongation Factors; Protein Processing, Post-Translational; Saccharomyces cerevisiae

1988
Evidence of a yeast proteinase specific for elongation factor 2.
    FEBS letters, 1988, Dec-05, Volume: 241, Issue:1-2

    Topics: Adenosine Diphosphate Ribose; NAD; Peptide Elongation Factor 2; Peptide Elongation Factors; Peptide Hydrolases; Saccharomyces

1988
Modulation of diphthamide synthesis by 5'-deoxy-5'-methylthioadenosine in murine lymphoma cells.
    Biochimica et biophysica acta, 1986, Sep-19, Volume: 888, Issue:2

    Topics: Adenosine; Adenosine Diphosphate Ribose; Animals; Cell Line; Deoxyadenosines; Diphtheria Toxin; Histidine; Lymphoma; Mice; Peptide Elongation Factor 2; Peptide Elongation Factors; Purine-Nucleoside Phosphorylase; S-Adenosylmethionine; Thionucleosides

1986
On the nature of cellular ADP-ribosyltransferase from rat liver specific for elongation factor 2.
    Biochemical and biophysical research communications, 1986, Sep-30, Volume: 139, Issue:3

    Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Diphtheria Toxin; Electrophoresis, Polyacrylamide Gel; Guanosine Triphosphate; Kinetics; Liver; Pentosyltransferases; Peptide Elongation Factor 2; Peptide Elongation Factors; Rats

1986
His-426 of the Pseudomonas aeruginosa exotoxin A is required for ADP-ribosylation of elongation factor II.
    Proceedings of the National Academy of Sciences of the United States of America, 1988, Volume: 85, Issue:23

    Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Bacterial Toxins; Cloning, Molecular; Escherichia coli; Exotoxins; Genes; Genes, Bacterial; Histidine; Models, Molecular; Mutation; Peptide Elongation Factor 2; Peptide Elongation Factors; Plasmids; Protein Conformation; Pseudomonas aeruginosa; Pseudomonas aeruginosa Exotoxin A; Species Specificity; Virulence Factors

1988
ADP-ribosyl proteins formed by pertussis toxin are specifically cleaved by mercury ions.
    Biological chemistry Hoppe-Seyler, 1988, Volume: 369, Issue:7

    Topics: Adenosine Diphosphate Ribose; Animals; Cattle; Cysteine; Histones; Hydrolysis; Mercury; Mitochondria, Heart; NAD; Peptide Elongation Factor 2; Peptide Elongation Factors; Peptides; Pertussis Toxin; Proteins; Submitochondrial Particles; Transducin; Virulence Factors, Bordetella

1988
Purification and characterization of peptide-elongation factor 2 (aEF-2) from an extremely halophilic archaebacterium Halobacterium halobium.
    European journal of biochemistry, 1988, Jan-04, Volume: 170, Issue:3

    Topics: Adenosine Diphosphate Ribose; Amino Acids; Diphtheria Toxin; Halobacterium; Kinetics; Molecular Weight; Peptide Elongation Factor 2; Peptide Elongation Factors; Ribosomes

1988
Post-translational modifications of the elongation factor 2.
    Advances in experimental medicine and biology, 1988, Volume: 231

    Topics: Adenosine Diphosphate Ribose; Animals; Diphtheria Toxin; Peptide Elongation Factor 2; Peptide Elongation Factors; Protein Processing, Post-Translational

1988
Purification of elongation factor 2 from human placenta and evidence of its fragmentation patterns in various eukaryotic sources.
    The Biochemical journal, 1987, Jun-01, Volume: 244, Issue:2

    Topics: Adenosine Diphosphate Ribose; Amino Acids; Diphtheria Toxin; Electrophoresis, Polyacrylamide Gel; Humans; Liver; Peptide Elongation Factor 2; Peptide Elongation Factors; Peptide Fragments; Placenta; Yeasts

1987
Identification of the major Mr 100,000 substrate for calmodulin-dependent protein kinase III in mammalian cells as elongation factor-2.
    The Journal of biological chemistry, 1987, Dec-25, Volume: 262, Issue:36

    Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Amino Acids; Animals; Calmodulin; Guanosine Triphosphate; Molecular Weight; Peptide Elongation Factor 2; Peptide Elongation Factors; Peptide Mapping; Phosphorylation; Protein Kinases; Rats

1987
Nucleotide binding to elongation factor 2 inactivated by diphtheria toxin.
    FEBS letters, 1986, Nov-24, Volume: 208, Issue:2

    Topics: Adenosine Diphosphate Ribose; Diphtheria Toxin; Guanine Nucleotides; Guanosine Triphosphate; In Vitro Techniques; Peptide Elongation Factor 2; Peptide Elongation Factors; Ribosomes; Triticum

1986
Characterization of diphtheria-toxin-resistant mutants lacking receptor function or containing nonribosylatable elongation factor 2.
    Somatic cell and molecular genetics, 1985, Volume: 11, Issue:5

    Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Bacterial Toxins; Cell Line; Cricetinae; Cricetulus; Diphtheria Toxin; Drug Resistance; Exotoxins; Female; Genes; Heparin-binding EGF-like Growth Factor; Hybrid Cells; Intercellular Signaling Peptides and Proteins; Mutation; Ovary; Peptide Elongation Factor 2; Peptide Elongation Factors; Phenotype; Protein Biosynthesis; Pseudomonas aeruginosa Exotoxin A; Receptors, Cell Surface; Receptors, Cholinergic; Virulence Factors

1985
Reduced ribosomal binding of eukaryotic elongation factor 2 following ADP-ribosylation. Difference in binding selectivity between polyribosomes and reconstituted monoribosomes.
    Biochimica et biophysica acta, 1985, Feb-20, Volume: 824, Issue:2

    Topics: Adenosine Diphosphate Ribose; Animals; Diphtheria Toxin; Guanosine Diphosphate; Guanosine Triphosphate; NAD; Nucleoside Diphosphate Sugars; Peptide Elongation Factor 2; Peptide Elongation Factors; Protein Binding; Rabbits; Rats; Ribosomes; Structure-Activity Relationship

1985
Quantal entry of diphtheria toxin to the cytosol.
    The Journal of biological chemistry, 1985, Mar-10, Volume: 260, Issue:5

    Topics: Adenosine Diphosphate Ribose; Ammonium Chloride; Animals; Autoradiography; Cell Line; Chlorocebus aethiops; Cycloheximide; Cytosol; Diphtheria Toxin; Kidney; Kinetics; Peptide Elongation Factor 2; Peptide Elongation Factors

1985
Localization of the sites of ADP-ribosylation and GTP binding in the eukaryotic elongation factor EF-2.
    European journal of biochemistry, 1985, Apr-15, Volume: 148, Issue:2

    Topics: Adenosine Diphosphate Ribose; Affinity Labels; Binding Sites; Chymotrypsin; Guanosine Triphosphate; Hydrolysis; Nucleoside Diphosphate Sugars; Peptide Elongation Factor 2; Peptide Elongation Factors; Peptide Fragments; Structure-Activity Relationship; Succinimides; Trypsin

1985
Primary structure of elongation factor 2 around the site of ADP-ribosylation is highly conserved from archaebacteria to eukaryotes.
    FEBS letters, 1985, Jun-03, Volume: 185, Issue:1

    Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Chromatography, Gel; Chromatography, High Pressure Liquid; Euryarchaeota; Halobacterium; Nucleoside Diphosphate Sugars; Peptide Elongation Factor 2; Peptide Elongation Factors; Peptide Fragments; Thermoplasma; Trypsin

1985
Cloning and expression of a gene segment encoding the enzymatic moiety of Pseudomonas aeruginosa exotoxin A.
    Journal of bacteriology, 1984, Volume: 159, Issue:2

    Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Bacterial Toxins; Base Sequence; Cloning, Molecular; DNA Restriction Enzymes; Exotoxins; Genes; Genes, Bacterial; Nucleic Acid Hybridization; Peptide Elongation Factor 2; Peptide Elongation Factors; Plasmids; Pseudomonas aeruginosa; Pseudomonas aeruginosa Exotoxin A; Virulence Factors

1984
Endogenous ADP-ribosylation of elongation factor 2 in polyribosome fraction of rabbit reticulocytes.
    FEBS letters, 1984, Oct-15, Volume: 176, Issue:1

    Topics: Adenosine Diphosphate Ribose; Animals; NAD; Nucleoside Diphosphate Sugars; Nucleotidyltransferases; Peptide Elongation Factor 2; Peptide Elongation Factors; Poly(ADP-ribose) Polymerases; Polyribosomes; Rabbits; Reticulocytes

1984
Eukaryotic elongation factor 2 loses its non-specific affinity for RNA and leaves polyribosomes as a result of ADP-ribosylation.
    FEBS letters, 1984, Oct-29, Volume: 176, Issue:2

    Topics: Adenosine Diphosphate Ribose; Animals; Centrifugation, Density Gradient; Chromatography, Affinity; Diphtheria Toxin; Escherichia coli; Niacinamide; Nucleoside Diphosphate Sugars; Peptide Elongation Factor 2; Peptide Elongation Factors; Polyribosomes; Rabbits; Reticulocytes; RNA; RNA, Bacterial

1984
Diphtheria toxin. Site and configuration of ADP-ribosylation of diphthamide in elongation factor 2.
    The Journal of biological chemistry, 1981, Aug-25, Volume: 256, Issue:16

    Topics: Adenosine Diphosphate Ribose; Animals; Bacterial Toxins; Brain; Cattle; Diphtheria Toxin; Histidine; Magnetic Resonance Spectroscopy; NAD+ Nucleosidase; Nucleoside Diphosphate Sugars; Peptide Chain Elongation, Translational; Peptide Elongation Factor 2; Peptide Elongation Factors; Ribonucleosides; Spleen; Swine

1981
Purification and properties of an altered form of elongation factor 2 from mutant cells resistant to intoxication by diphtheria toxin.
    European journal of biochemistry, 1983, Aug-01, Volume: 134, Issue:2

    Topics: Adenosine Diphosphate Ribose; Animals; Cell Line; Cell Transformation, Viral; Cricetinae; Diphtheria Toxin; Drug Resistance; Kidney; Mutation; Peptide Elongation Factor 2; Peptide Elongation Factors; Polyomavirus

1983
Diphthamide in elongation factor 2: ADP-ribosylation, purification, and properties.
    Methods in enzymology, 1984, Volume: 106

    Topics: Adenosine Diphosphate Ribose; Diphtheria Toxin; Histidine; NAD; Nucleoside Diphosphate Sugars; Peptide Elongation Factor 2; Peptide Elongation Factors; Phosphorus Radioisotopes; Protein Processing, Post-Translational; Radioisotope Dilution Technique

1984
Occurrence of diphthamide in archaebacteria.
    Journal of bacteriology, 1983, Volume: 153, Issue:3

    Topics: Adenosine Diphosphate Ribose; Archaea; Bacteria; Histidine; Peptide Elongation Factor 2; Peptide Elongation Factors; Protein Processing, Post-Translational

1983
Entry of diphtheria toxin into cells: possible existence of cellular factor(s) for entry of diphtheria toxin into cells was studied in somatic cell hybrids and hybrid toxins.
    The Journal of cell biology, 1984, Volume: 98, Issue:2

    Topics: Adenosine Diphosphate Ribose; Animals; Carcinoma, Ehrlich Tumor; Cell Membrane; Diphtheria Toxin; Fibroblasts; Heparin-binding EGF-like Growth Factor; Humans; Hybrid Cells; Intercellular Signaling Peptides and Proteins; Kinetics; Male; Mice; Peptide Elongation Factor 2; Peptide Elongation Factors; Protein Biosynthesis; Receptors, Cell Surface; Receptors, Cholinergic; Skin

1984
Functional groups of elongation factor 2 involved in interactions with guanosine nucleotides and ribosomes.
    FEBS letters, 1983, Apr-18, Volume: 154, Issue:2

    Topics: Adenosine Diphosphate Ribose; Ethylmaleimide; Guanine Nucleotides; Guanosine Triphosphate; Peptide Elongation Factor 2; Peptide Elongation Factors; Ribosomes; Trinitrobenzenesulfonic Acid

1983
ADP-ribosylation of elongation factor 2 by diphtheria toxin. Isolation and properties of the novel ribosyl-amino acid and its hydrolysis products.
    The Journal of biological chemistry, 1980, Nov-25, Volume: 255, Issue:22

    Topics: Adenosine Diphosphate Ribose; Diphtheria Toxin; Histidine; Hydrolysis; Kinetics; Nucleoside Diphosphate Sugars; Peptide Elongation Factor 2; Peptide Elongation Factors; Ribonucleosides; Saccharomyces cerevisiae

1980
Determination of elongation factor 2 associated with native mammalian ribosomes.
    Biochimica et biophysica acta, 1982, May-31, Volume: 697, Issue:2

    Topics: Adenosine Diphosphate Ribose; Animals; Diphtheria Toxin; Kinetics; Liver; Mice; Peptide Elongation Factor 2; Peptide Elongation Factors; Polyribosomes; Rabbits; Reticulocytes; Ribosomes

1982
Association of elongation factor 2 with layer ribosomes of dimethylnitrosamine-treated mice.
    Chemico-biological interactions, 1981, Volume: 36, Issue:1

    Topics: Adenosine Diphosphate Ribose; Animals; Dimethylnitrosamine; Liver; Mice; Peptide Elongation Factor 2; Peptide Elongation Factors; Polyribosomes; Ribosomes; Subcellular Fractions

1981
Kinetics of adenosinediphosphoribosylation of elongation factor 2 in cells exposed to diphtheria toxin.
    Infection and immunity, 1981, Volume: 32, Issue:2

    Topics: Adenosine Diphosphate Ribose; Animals; Cell Line; Cricetinae; Cytoplasm; Diphtheria Toxin; HeLa Cells; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Kinetics; Models, Biological; Nucleoside Diphosphate Sugars; Peptide Elongation Factor 2; Peptide Elongation Factors; Receptors, Cell Surface; Receptors, Immunologic

1981
Diphtheria toxin resistance in human lymphoblast lines.
    Biochemical and biophysical research communications, 1980, Jun-30, Volume: 94, Issue:4

    Topics: Adenosine Diphosphate Ribose; Cell Division; Cell Line; Cell-Free System; Diphtheria Toxin; Dose-Response Relationship, Drug; Drug Resistance; Humans; Lymphocytes; Peptide Elongation Factor 2; Peptide Elongation Factors; Protein Biosynthesis

1980
ADP-ribosylation of elongation factor 2 by diphtheria toxin. NMR spectra and proposed structures of ribosyl-diphthamide and its hydrolysis products.
    The Journal of biological chemistry, 1980, Nov-25, Volume: 255, Issue:22

    Topics: Adenosine Diphosphate Ribose; Diphtheria Toxin; Histidine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Nucleoside Diphosphate Sugars; Peptide Elongation Factor 2; Peptide Elongation Factors; Ribonucleosides

1980
Recognition of elongation factor 2 by diphtheria toxin is not solely defined by the presence of diphthamide.
    FEBS letters, 1980, Oct-20, Volume: 120, Issue:1

    Topics: Adenosine Diphosphate Ribose; Animals; Diphtheria Toxin; Histidine; Kinetics; Liver; Molecular Weight; Peptide Elongation Factor 2; Peptide Elongation Factors; Rats; Trypsin

1980
Studies on the polypeptide elongation factor 2 from Sulfolobus solfataricus. Interaction with guanosine nucleotides and GTPase activity stimulated by ribosomes.
    The Journal of biological chemistry, 1995, Sep-08, Volume: 270, Issue:36

    Topics: Adenosine Diphosphate Ribose; Catalysis; Enzyme Activation; GTP Phosphohydrolase-Linked Elongation Factors; Guanine Nucleotides; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Peptide Elongation Factor 2; Peptide Elongation Factors; Ribosomes; Sulfolobus

1995
Introduction of additional charges as an aid in protein purification: isolation of elongation factor 2 from Sulfolobus acidocaldarius by preparative isoelectric focusing before and after ADP-ribosylation.
    Protein expression and purification, 1994, Volume: 5, Issue:6

    Topics: Adenosine Diphosphate Ribose; Chromatography, Gel; Diphtheria Toxin; Enzyme-Linked Immunosorbent Assay; Isoelectric Focusing; Peptide Elongation Factor 2; Peptide Elongation Factors; Sulfolobus acidocaldarius

1994
Active-site mutations of the diphtheria toxin catalytic domain: role of histidine-21 in nicotinamide adenine dinucleotide binding and ADP-ribosylation of elongation factor 2.
    Biochemistry, 1994, May-03, Volume: 33, Issue:17

    Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Binding Sites; Calorimetry; Cloning, Molecular; Diphtheria Toxin; Escherichia coli; Genes, Synthetic; Histidine; Hydrogen Bonding; Kinetics; Mutagenesis, Insertional; NAD; NAD+ Nucleosidase; Peptide Elongation Factor 2; Peptide Elongation Factors; Poly(ADP-ribose) Polymerases; Recombinant Fusion Proteins; Recombinant Proteins; Restriction Mapping

1994
The 100-kDa protein, whose phosphorylation precedes the fusion of chick embryonic myoblasts, is the eukaryotic elongation factor-2.
    Biochemical and biophysical research communications, 1994, Jan-14, Volume: 198, Issue:1

    Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Amino Acids; Animals; Chick Embryo; Electrophoresis, Polyacrylamide Gel; Membrane Fusion; Molecular Weight; Muscles; Peptide Elongation Factor 2; Peptide Elongation Factors; Phosphoproteins; Phosphorylation

1994
Purification of a nitric oxide-stimulated ADP-ribosylated protein using biotinylated beta-nicotinamide adenine dinucleotide.
    Biochemistry, 1993, Mar-09, Volume: 32, Issue:9

    Topics: Adenosine Diphosphate Ribose; Animals; Biotin; Brain Chemistry; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; NAD; Nerve Tissue Proteins; Nitric Oxide; Peptide Elongation Factor 2; Peptide Elongation Factors; Rats

1993
Expression of non-ADP-ribosylatable, diphtheria toxin-resistant elongation factor 2 in Saccharomyces cerevisiae.
    Biochemical and biophysical research communications, 1993, Mar-31, Volume: 191, Issue:3

    Topics: Adenosine Diphosphate Ribose; Base Sequence; Cloning, Molecular; Diphtheria Toxin; DNA Mutational Analysis; Molecular Sequence Data; Mutagenesis, Insertional; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Peptide Elongation Factor 2; Peptide Elongation Factors; Saccharomyces cerevisiae; Spores, Fungal

1993
Role of CAS, a human homologue to the yeast chromosome segregation gene CSE1, in toxin and tumor necrosis factor mediated apoptosis.
    Biochemistry, 1996, May-28, Volume: 35, Issue:21

    Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Antibodies; Antigens, Polyomavirus Transforming; Apoptosis; Bacterial Toxins; Breast Neoplasms; Cell Line; Cellular Apoptosis Susceptibility Protein; Diphtheria Toxin; DNA, Antisense; DNA, Neoplasm; Drug Resistance, Neoplasm; Exotoxins; Female; Fungal Proteins; Gene Library; Genes, Fungal; HeLa Cells; Humans; Immunotoxins; Lymphotoxin-alpha; Nuclear Proteins; Nucleocytoplasmic Transport Proteins; Peptide Elongation Factor 2; Peptide Elongation Factors; Protein Biosynthesis; Proteins; Pseudomonas aeruginosa; Pseudomonas aeruginosa Exotoxin A; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Virulence Factors

1996
Fused polycationic peptide mediates delivery of diphtheria toxin A chain to the cytosol in the presence of anthrax protective antigen.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Aug-06, Volume: 93, Issue:16

    Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Antigens, Bacterial; Bacterial Toxins; Biological Transport; CHO Cells; Cricetinae; Cytosol; Diphtheria Toxin; Molecular Sequence Data; Peptide Elongation Factor 2; Peptide Elongation Factors; Peptide Fragments; Peptides; Polylysine; Recombinant Fusion Proteins; Structure-Activity Relationship

1996
Effect of oxidative stress, produced by cumene hydroperoxide, on the various steps of protein synthesis. Modifications of elongation factor-2.
    The Journal of biological chemistry, 1996, Sep-20, Volume: 271, Issue:38

    Topics: Adenosine Diphosphate Ribose; Animals; Benzene Derivatives; Female; Liver; Malondialdehyde; Oxidants; Oxidation-Reduction; Oxidative Stress; Peptide Chain Elongation, Translational; Peptide Elongation Factor 2; Peptide Elongation Factors; Polyribosomes; Rats; Rats, Wistar

1996
The site for GTP hydrolysis on the archaeal elongation factor 2 is unmasked by aliphatic alcohols.
    Biochimie, 1996, Volume: 78, Issue:10

    Topics: Adenosine Diphosphate Ribose; Alcohols; Barium Compounds; Binding Sites; Cations, Divalent; Chlorides; Ethylene Glycol; Ethylene Glycols; GTP Phosphohydrolase-Linked Elongation Factors; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hydrogen-Ion Concentration; Hydrolysis; Peptide Elongation Factor 2; Peptide Elongation Factors; Sulfolobus; Temperature

1996
Use of biotinylated NAD to label and purify ADP-ribosylated proteins.
    Methods in enzymology, 1997, Volume: 280

    Topics: Adenosine Diphosphate Ribose; Biotin; Chromatography, Affinity; Glyceraldehyde-3-Phosphate Dehydrogenases; GTP-Binding Proteins; NAD; Peptide Elongation Factor 2; Peptide Elongation Factors; Poly(ADP-ribose) Polymerases; Protein Processing, Post-Translational; Proteins

1997
Interactions of elongation factor 2 with the cytoskeleton and interference with DNase I binding to actin.
    European journal of biochemistry, 1998, Aug-15, Volume: 256, Issue:1

    Topics: Actins; Adenosine Diphosphate Ribose; Chromatography, Gel; Cytoskeleton; Deoxyribonuclease I; Microscopy, Electron; Peptide Elongation Factor 2; Peptide Elongation Factors; Protein Binding; Viscosity

1998
Suppression of protein synthesis in brain during hibernation involves inhibition of protein initiation and elongation.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Nov-24, Volume: 95, Issue:24

    Topics: Adenosine Diphosphate Ribose; Animals; Autoradiography; Brain; Carbon Radioisotopes; Eukaryotic Initiation Factor-2; Hibernation; Leucine; Nerve Tissue Proteins; Peptide Chain Elongation, Translational; Peptide Chain Initiation, Translational; Peptide Elongation Factor 2; Peptide Elongation Factors; Phosphorylation; Protein Biosynthesis; Ribosomes; RNA, Messenger; Sciuridae; Sensitivity and Specificity; Transcription, Genetic

1998
On the mode of inhibition of eukaryotic protein synthesis by ADP-ribosylation of elongation factor 2.
    IUBMB life, 1999, Volume: 48, Issue:5

    Topics: Adenosine Diphosphate Ribose; Animals; Binding Sites; Collodion; Filtration; Guanine Nucleotides; Kinetics; Peptide Elongation Factor 2; Protein Biosynthesis; Proteins; Rats; Ribosomes

1999
Cytoplasmic inhibitor of eEF-2 ADP-ribosylation catalyzed by diphtheria toxin or endogenous transferase in rat liver cells.
    Biochemical and biophysical research communications, 2000, Mar-16, Volume: 269, Issue:2

    Topics: Adenosine Diphosphate Ribose; Animals; Catalysis; Cells, Cultured; Diphtheria Toxin; Liver; Male; Peptide Elongation Factor 2; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar

2000
Heterogeneity of cardiac rat and human elongation factor 2.
    Electrophoresis, 2000, Volume: 21, Issue:13

    Topics: Adenosine Diphosphate Ribose; Animals; Animals, Newborn; Autoradiography; Blotting, Western; Cardiomyopathy, Dilated; Cells, Cultured; Cytosol; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Humans; Hydrogen-Ion Concentration; Isoelectric Focusing; Myocardium; Peptide Elongation Factor 2; Phosphorylation; Protein Processing, Post-Translational; Rats; Rats, Wistar; Silver Staining; Species Specificity

2000
Eukaryotic elongation factor 2 can bind to the synthetic oligoribonucleotide that mimics sarcin/ricin domain of rat 28S ribosomal RNA.
    Molecular and cellular biochemistry, 2001, Volume: 223, Issue:1-2

    Topics: Adenosine Diphosphate Ribose; Animals; Guanosine Diphosphate; Guanylyl Imidodiphosphate; Liver; Nucleic Acid Conformation; Oligoribonucleotides; Peptide Elongation Factor 2; Potassium Chloride; Protein Binding; Protein Structure, Tertiary; Rats; RNA-Binding Proteins; RNA, Ribosomal, 28S

2001
Eukaryotic elongation factor-2 (eEF-2) activity in bovine mammary tissue in relation to milk protein synthesis.
    The Journal of dairy research, 2002, Volume: 69, Issue:2

    Topics: Adenosine Diphosphate Ribose; Animals; Cattle; Diphtheria Toxin; Female; Lactation; Liver; Mammary Glands, Animal; Milk Proteins; Muscle, Skeletal; Peptide Elongation Factor 2

2002
Toward the elucidation of the catalytic mechanism of the mono-ADP-ribosyltransferase activity of Pseudomonas aeruginosa exotoxin A.
    Biochemistry, 2004, Jan-13, Volume: 43, Issue:1

    Topics: 1-Naphthylamine; Adenosine Diphosphate; Adenosine Diphosphate Ribose; Adenosine Monophosphate; ADP Ribose Transferases; Bacterial Toxins; Binding, Competitive; Catalysis; Enzyme Activation; Exotoxins; Fluorescence Resonance Energy Transfer; Kinetics; Mutagenesis, Site-Directed; NAD; Naphthalimides; Niacinamide; Peptide Elongation Factor 2; Protein Binding; Pseudomonas aeruginosa; Pseudomonas aeruginosa Exotoxin A; Quinolones; Recombinant Proteins; Substrate Specificity; Virulence Factors

2004
Transition state structure for ADP-ribosylation of eukaryotic elongation factor 2 catalyzed by diphtheria toxin.
    Biochemistry, 2004, Feb-10, Volume: 43, Issue:5

    Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Binding, Competitive; Carbon Radioisotopes; Catalysis; Catalytic Domain; Diphtheria Toxin; Hydrolysis; Kinetics; NAD+ Nucleosidase; Nitrogen Isotopes; Peptide Elongation Factor 2; Peptide Fragments; Saccharomyces cerevisiae Proteins; Tritium

2004
Actin--an inhibitor of eukaryotic elongation factor activities.
    Biochemical and biophysical research communications, 2004, May-14, Volume: 317, Issue:4

    Topics: Actins; Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Cytosol; Deoxyribonuclease I; Diphtheria Toxin; Dose-Response Relationship, Drug; Hepatocytes; Inhibitory Concentration 50; Muscle, Skeletal; Peptide Elongation Factor 1; Peptide Elongation Factor 2; Peptides; Rabbits; Rats; Ribosomes

2004
Crystal structure of ADP-ribosylated ribosomal translocase from Saccharomyces cerevisiae.
    The Journal of biological chemistry, 2004, Oct-29, Volume: 279, Issue:44

    Topics: Adenosine Diphosphate Ribose; Antifungal Agents; Binding Sites; Crystallization; Guanosine Diphosphate; Indenes; Peptide Elongation Factor 2; Protein Transport; Ribosomes; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins

2004
Effect of oxidative stress on in vivo ADP-ribosylation of eukaryotic elongation factor 2.
    The international journal of biochemistry & cell biology, 2005, Volume: 37, Issue:1

    Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Bacterial Proteins; Carbon Radioisotopes; Diphtheria Toxin; Humans; Hydrogen Peroxide; K562 Cells; NAD; Oxidative Stress; Peptide Elongation Factor 2; Protein Binding; Protein Processing, Post-Translational

2005
Mechanistic aspects of the deoxyribonuclease activity of diphtheria toxin.
    Biochimica et biophysica acta, 2005, Feb-14, Volume: 1747, Issue:1

    Topics: Adenosine; Adenosine Diphosphate Ribose; ADP Ribose Transferases; Azides; Binding Sites; Catalysis; Cations, Divalent; Cell Line; Cycloheximide; Diphtheria Toxin; DNA; Endodeoxyribonucleases; Humans; NAD; Niacinamide; Oligoribonucleotides; Peptide Elongation Factor 2; Protein Biosynthesis; Substrate Specificity

2005
A nonradioactive, cell-free method for measuring protein synthesis inhibition by Pseudomonas exotoxin.
    Analytical biochemistry, 2006, Jun-15, Volume: 353, Issue:2

    Topics: Adenosine Diphosphate Ribose; Bacterial Proteins; beta-Galactosidase; Cell-Free System; Enzyme Activation; Genes, Reporter; NAD; Peptide Elongation Factor 2; Protein Biosynthesis; Protein Synthesis Inhibitors; Transcription, Genetic

2006
Human alpha-defensins neutralize toxins of the mono-ADP-ribosyltransferase family.
    The Biochemical journal, 2006, Oct-15, Volume: 399, Issue:2

    Topics: Adenosine Diphosphate Ribose; alpha-Defensins; Animals; Cell Death; Corynebacterium diphtheriae; Diphtheria Toxin; Exotoxins; HeLa Cells; Humans; Kinetics; Mice; NAD; Peptide Elongation Factor 2; Protein Binding; Substrate Specificity; Thermodynamics

2006
Diphtheria toxin mutant CRM197 possesses weak EF2-ADP-ribosyl activity that potentiates its anti-tumorigenic activity.
    Journal of biochemistry, 2007, Volume: 142, Issue:1

    Topics: Adenosine Diphosphate Ribose; Animals; Antibodies, Monoclonal; Antineoplastic Agents; Bacterial Proteins; Cell Line, Tumor; Chlorocebus aethiops; Diphtheria Toxin; Female; Heparin; Heparin-binding EGF-like Growth Factor; Intercellular Signaling Peptides and Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; Mitogens; Mutation; Peptide Elongation Factor 2; Vero Cells

2007
Endogenous ADP-ribosylation of eukaryotic elongation factor 2 and its 32 kDa tryptic fragment.
    Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al, 2007, Volume: 31, Issue:1

    Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Bacterial Toxins; Glycosylation; Peptide Elongation Factor 2; Peptide Fragments; Rats

2007
Quantification of diphtheria toxin mediated ADP-ribosylation in a solid-phase assay.
    Clinical chemistry, 2007, Volume: 53, Issue:9

    Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Bacterial Toxins; Blotting, Western; Catalytic Domain; Colorimetry; Diphtheria Toxin; Exotoxins; Peptide Elongation Factor 2; Pseudomonas; Pseudomonas aeruginosa Exotoxin A; Recombinant Fusion Proteins; Virulence Factors

2007
Investigating the ADP-ribosyltransferase activity of sirtuins with NAD analogues and 32P-NAD.
    Biochemistry, 2009, Apr-07, Volume: 48, Issue:13

    Topics: Acetylation; Adenosine Diphosphate Ribose; ADP Ribose Transferases; Alkynes; Animals; Biocatalysis; Diphtheria Toxin; HeLa Cells; Histone Deacetylases; Histones; Humans; Hydrolysis; Kinetics; Mice; Models, Biological; NAD; Peptide Elongation Factor 2; Phosphorus Radioisotopes; Saccharomyces cerevisiae; Sirtuins; Substrate Specificity

2009
Haploid genetic screens in human cells identify host factors used by pathogens.
    Science (New York, N.Y.), 2009, Nov-27, Volume: 326, Issue:5957

    Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Amino Acid Sequence; Antigens, Bacterial; Bacterial Toxins; Biosynthetic Pathways; Carboxylic Ester Hydrolases; Cell Line, Tumor; Diphtheria Toxin; Exotoxins; Genes; Genetic Testing; Haploidy; Histidine; Host-Pathogen Interactions; Humans; Influenza A Virus, H1N1 Subtype; Methyltransferases; Molecular Sequence Data; Monosaccharide Transport Proteins; Mutagenesis, Insertional; N-Acylneuraminate Cytidylyltransferase; Peptide Elongation Factor 2; Proteins; Pseudomonas aeruginosa Exotoxin A; Virulence Factors

2009
Characterization of a Chinese hamster ovary cell mutant having a mutation in elongation factor-2.
    PloS one, 2010, Feb-05, Volume: 5, Issue:2

    Topics: Adenosine Diphosphate Ribose; Alleles; Amino Acid Sequence; Animals; Blotting, Western; Cell Survival; CHO Cells; Cricetinae; Cricetulus; Drug Resistance; Electrophoresis, Polyacrylamide Gel; Endocytosis; Fluorescence Resonance Energy Transfer; Genotype; Histidine; Molecular Sequence Data; Mutation; Peptide Elongation Factor 2; Protein Biosynthesis; Sequence Homology, Amino Acid; Toxins, Biological

2010
Molecular control of the amount, subcellular location, and activity state of translation elongation factor 2 in neurons experiencing stress.
    Free radical biology & medicine, 2013, Volume: 61

    Topics: 14-3-3 Proteins; Adenosine Diphosphate Ribose; Animals; Benzene Derivatives; Cell Survival; Cells, Cultured; Exportin 1 Protein; HCT116 Cells; Humans; Karyopherins; Lipid Peroxidation; Neurons; Oxidative Stress; Peptide Elongation Factor 2; Phosphorylation; Rats; Receptors, Cytoplasmic and Nuclear; Tumor Suppressor Protein p53

2013
Modes of action of ADP-ribosylated elongation factor 2 in inhibiting the polypeptide elongation cycle: a modeling study.
    PloS one, 2013, Volume: 8, Issue:7

    Topics: Adenosine Diphosphate Ribose; Carbon Radioisotopes; Computer Simulation; Models, Biological; Peptide Chain Elongation, Translational; Peptide Elongation Factor 2; Ribosomes

2013
Structural Insights into
    Journal of chemical information and modeling, 2023, 03-13, Volume: 63, Issue:5

    Topics: Adenosine Diphosphate Ribose; Histidine; Molecular Dynamics Simulation; NAD; Peptide Elongation Factor 2; Pseudomonas aeruginosa; Pseudomonas aeruginosa Exotoxin A

2023