peptide-a and carbetocin

peptide-a has been researched along with carbetocin* in 1 studies

Other Studies

1 other study(ies) available for peptide-a and carbetocin

ArticleYear
Capillary electrochromatography/nanoelectrospray mass spectrometry for attomole characterization of peptides.
    Rapid communications in mass spectrometry : RCM, 2000, Volume: 14, Issue:16

    The successful coupling of capillary electrochromatography (CEC) to an ion trap mass spectrometer via a nanoelectrospray interface (nESI) is described. Using a conductively coated tip butted to the end of a CEC column, it was possible to obtain a stable spray without any sheath liquid being employed. Selected small peptides were separated with CEC columns (100 microm i.d./25 cm long) packed with 3 microm Hypersil C8 or C18 bonded silica particles with an eluent composed of ammonium acetate/acetonitrile. Peptide mixtures of desmopressin, peptide A, oxytocin, carbetocin and [Met(5)]-enkephalin were detected in the mid-attomole range, which is the lowest amount analyzed using CEC combined with MS detection. It was also observed that sensitivity can be compromised at higher separation voltages. We demonstrate that CEC/nESI-MS, at the current stage of development, represents one of the most sensitive systems for peptide analysis.

    Topics: Amino Acid Sequence; Chromatography; Deamino Arginine Vasopressin; Enkephalin, Methionine; Mass Spectrometry; Oncogene Protein pp60(v-src); Oxytocin; Peptide Fragments; Peptides; Quality Control; Sensitivity and Specificity

2000