peplomycin has been researched along with bleomycetin* in 1 studies
1 trial(s) available for peplomycin and bleomycetin
Article | Year |
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[Chemotherapy in disseminated malignant skin melanoma with a combination of nitrosomethylurea, vincristine, peplomycin or bleomycetin].
A study of combination chemotherapy with nitrosomethylurea, vincristine and peplomycin or bleomycetin given an 5-6-day cycles showed the cytotoxic regimens to be more effective than single-agent treatment with dacarbazine for disseminated melanoma of the skin with metastases to the subcutaneous fat, lymph nodes, lungs and other viscera. In a group of 129 such patients, complete (12%) and partial remission (38%) was observed with the former combination whereas with nitrosomethylurea, vincristine and bleomycetin, complete and partial response rates were 7.6 and 26.9%, respectively. Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Female; Humans; Male; Melanoma; Methylnitrosourea; Middle Aged; Neoplasm Recurrence, Local; Peplomycin; Prospective Studies; Remission Induction; Skin Neoplasms; Vincristine | 1991 |