peoniflorin has been researched along with angelicin* in 1 studies
1 other study(ies) available for peoniflorin and angelicin
| Article | Year |
|---|---|
Established UPLC-MS/MS procedure for multicomponent quantitative analysis in rat plasma: A contrastive pharmacokinetics study of Qiangshen tablet in normal and kidney yang deficiency syndrome models.
Qiangshen tablet, an important prescription consisting of 14 kinds of Chinese herbal medicines, has been used for decades to treat kidney yang deficiency syndrome (KYDS) in China. Qiangshen tablet has been recorded in ChP (2015 edition) and possesses the effect of strengthening yang, invigorating qi and tonifying kidneys. In this research, a simple, reliable and specific method was established for simultaneous determination of stachydrine, psoralen, isopsoralen, morroniside, paeoniflorin and loganin in normal and KYDS rat plasma after intragastric administration of a Qiangshen tablet suspension by UPLC-MS/MS. Protein precipitation (PP) by acetonitrile and liquid-liquid extraction (LLE) by ethyl acetate - n-butanol (1: 1, v/v) were used for pretreatment of plasma samples. Chromatographic separation of two IS (Internal Standard) and six analytes was achieved using an ACQUITY UPLC® BEH C Topics: Animals; Chromatography, High Pressure Liquid; Drug Monitoring; Drugs, Chinese Herbal; Ficusin; Furocoumarins; Glucosides; Glycosides; Iridoids; Male; Metabolome; Monoterpenes; Proline; Rats; Rats, Sprague-Dawley; Tablets; Tandem Mass Spectrometry; Yang Deficiency | 2019 |