pentylenetetrazole has been researched along with vigabatrin in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (25.00) | 18.7374 |
| 1990's | 3 (15.00) | 18.2507 |
| 2000's | 8 (40.00) | 29.6817 |
| 2010's | 2 (10.00) | 24.3611 |
| 2020's | 2 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Casara, P; Knödgen, B; Sarhan, S; Seiler, N | 1 |
| Bernasconi, R; Christen, P; Hafner, T; Klein, M; Martin, P; Portet, C; Schmutz, M | 1 |
| Ferrendelli, JA; McKeon, AC; Miller, JW | 1 |
| Ferrendelli, JA; Mirski, MA | 1 |
| Ferrendelli, JA; McKeon, AC; Mirski, MA | 1 |
| Sarhan, S; Seiler, N | 1 |
| Sayin, U; Timmerman, W; Westerink, BH | 1 |
| Altug, T; Cengiz, S; Sayin, U | 1 |
| Chae, WG; Choi, H; Choi, J; Jahng, Y; Je, SM; Kim, EK; Kim, TH; Kim, YC; Lee, ES; Park, M; Zhao, LX | 1 |
| Haugvicová, R; Kubová, H; Mares, P | 1 |
| Andres, MM; Czuczwar, SJ; Luszczki, JJ; Wojcik-Cwikla, J | 1 |
| Armijo, JA; Cuadrado, A | 1 |
| Czuczwar, SJ; Luszczki, JJ | 1 |
| Czuczwar, SJ; Luszczki, JJ; Patsalos, PN; Ratnaraj, N | 1 |
| Andres-Mach, MM; Czuczwar, SJ; Dudra-Jastrzebska, M; Luszczki, JJ; Patsalos, PN; Ratnaraj, N; Sielski, M | 1 |
| Czuczwar, SJ; Luszczki, JJ; Nieoczym, D; Socała, K; Wlaź, P | 1 |
| Gernert, M; Gey, L; Löscher, W | 1 |
| Czuczwar, SJ; Krzyżanowski, M; Świąder, K; Świąder, MJ; Wróbel, A; Zakrocka, I; Łuszczki, JJ | 1 |
| Deking, LS; During, MJ; Feja, M; Gernert, M; Kaczmarek, E; Meller, S; Silverman, RB | 1 |
20 other study(ies) available for pentylenetetrazole and vigabatrin
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
(4S)-4-amino-5,6-heptadienoic acid (MDL 72483): a potent anticonvulsant GABA-T inhibitor.
Topics: 3-Mercaptopropionic Acid; 4-Aminobutyrate Transaminase; Aminocaproates; Animals; Anticonvulsants; Fatty Acids, Unsaturated; gamma-Aminobutyric Acid; Kinetics; Male; Mice; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures; Vigabatrin | 1991 |
Gamma-vinyl GABA: comparison of neurochemical and anticonvulsant effects in mice.
Topics: 4-Aminobutyrate Transaminase; Amino Acids; Aminocaproates; Animals; Anticonvulsants; Brain; gamma-Aminobutyric Acid; Injections; Isoniazid; Mice; Osmolar Concentration; Pentylenetetrazole; Picrotoxin; Seizures; Vigabatrin | 1988 |
Functional anatomy of pentylenetetrazol and electroshock seizures in the rat brainstem.
Topics: Aminocaproates; Animals; Brain; Brain Mapping; Brain Stem; Electric Stimulation; Female; Hypothalamus; Microinjections; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures; Thalamus; Vigabatrin | 1987 |
Anterior thalamic mediation of generalized pentylenetetrazol seizures.
Topics: Aminocaproates; Animals; Behavior, Animal; Bicuculline; Cerebral Cortex; Electroencephalography; Female; Guinea Pigs; Kainic Acid; Microinjections; Muscimol; Pentylenetetrazole; Seizures; Stereotaxic Techniques; Thalamic Nuclei; Vigabatrin | 1986 |
Anterior thalamus and substantia nigra: two distinct structures mediating experimental generalized seizures.
Topics: Aminocaproates; Animals; Electroshock; Female; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures; Substantia Nigra; Thalamic Nuclei; Vigabatrin | 1986 |
Synergistic anticonvulsant effects of GABA-T inhibitors and glycine.
Topics: 3-Mercaptopropionic Acid; 4-Aminobutyrate Transaminase; Amino Acids; Aminocaproates; Aminooxyacetic Acid; Animals; Anticonvulsants; Bicuculline; Brain Chemistry; Drug Synergism; Ethanolamines; Glycine; Male; Mice; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Sesterterpenes; Strychnine; Vigabatrin | 1984 |
The significance of extracellular GABA in the substantia nigra of the rat during seizures and anticonvulsant treatments.
Topics: Animals; Anticonvulsants; gamma-Aminobutyric Acid; Male; Microdialysis; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Substantia Nigra; Valproic Acid; Vigabatrin | 1995 |
Vigabatrin as an anticonvulsant against pentylenetetrazol seizures.
Topics: Aminocaproates; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Mice; Mice, Inbred BALB C; Pentylenetetrazole; Seizures; Vigabatrin | 1993 |
Design and synthesis of anticonvulsive agents as gamma-vinyl GABA-based potential dual acting prodrugs and their biological activities.
Topics: Animals; Anticonvulsants; Bicuculline; Drug Design; Mice; Pentylenetetrazole; Picrotoxin; Prodrugs; Seizures; Vigabatrin | 2000 |
Does vigabatrin possess an anticonvulsant action against pentylenetetrazol-induced seizures in developing rats?
Topics: Animals; Animals, Newborn; Anticonvulsants; Convulsants; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Pentylenetetrazole; Rats; Rats, Wistar; Reaction Time; Seizures; Severity of Illness Index; Vigabatrin | 2002 |
Pharmacological and behavioral characteristics of interactions between vigabatrin and conventional antiepileptic drugs in pentylenetetrazole-induced seizures in mice: an isobolographic analysis.
Topics: Animals; Anticonvulsants; Avoidance Learning; Behavior, Animal; Convulsants; Darkness; Light; Male; Mice; Motor Activity; Pain Threshold; Pentylenetetrazole; Psychomotor Performance; Seizures; Vigabatrin | 2005 |
Beneficial interaction between vigabatrin and valproate against seizures induced by pentylenetetrazole in mice.
Topics: Animals; Anticonvulsants; Brain; Convulsants; Drug Synergism; gamma-Aminobutyric Acid; Glutamic Acid; Male; Mice; Pentylenetetrazole; Valproic Acid; Vigabatrin | 2005 |
Isobolographic characterization of interactions between vigabatrin and tiagabine in two experimental models of epilepsy.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Epilepsy; Male; Mice; Nipecotic Acids; Pentylenetetrazole; Reaction Time; Statistics as Topic; Tiagabine; Vigabatrin | 2007 |
Isobolographic and behavioral characterizations of interactions between vigabatrin and gabapentin in two experimental models of epilepsy.
Topics: Amines; Animals; Anticonvulsants; Behavior, Animal; Brain; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Muscle Strength; Pentylenetetrazole; Psychomotor Performance; Seizures; Vigabatrin | 2008 |
Pharmacodynamic and pharmacokinetic interaction profiles of levetiracetam in combination with gabapentin, tiagabine and vigabatrin in the mouse pentylenetetrazole-induced seizure model: an isobolographic analysis.
Topics: Amines; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Interactions; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Levetiracetam; Male; Mice; Nipecotic Acids; Pentylenetetrazole; Piracetam; Seizures; Tiagabine; Tissue Distribution; Vigabatrin | 2009 |
Sildenafil influences the anticonvulsant activity of vigabatrin and gabapentin in the timed pentylenetetrazole infusion test in mice.
Topics: Amines; Animals; Anticonvulsants; Avoidance Learning; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Hand Strength; Male; Mice; Motor Skills; Pentylenetetrazole; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Seizures; Sildenafil Citrate; Sulfones; Vigabatrin | 2012 |
Continuous bilateral infusion of vigabatrin into the subthalamic nucleus: Effects on seizure threshold and GABA metabolism in two rat models.
Topics: Animals; Basal Ganglia; Disease Models, Animal; Electric Stimulation; Female; gamma-Aminobutyric Acid; Microinjections; Pentylenetetrazole; Rats, Wistar; Seizures; Substantia Nigra; Subthalamic Nucleus; Vigabatrin | 2016 |
Long-term vigabatrin treatment modifies pentylenetetrazole-induced seizures in mice: focused on GABA brain concentration.
Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Brain; Clonazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ethosuximide; gamma-Aminobutyric Acid; Mice; Pentylenetetrazole; Seizures; Time Factors; Valproic Acid; Vigabatrin | 2020 |
OV329, a novel highly potent γ-aminobutyric acid aminotransferase inactivator, induces pronounced anticonvulsant effects in the pentylenetetrazole seizure threshold test and in amygdala-kindled rats.
Topics: Amygdala; Animals; Anticonvulsants; Epilepsy; Female; gamma-Aminobutyric Acid; Humans; Kindling, Neurologic; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Transaminases; Vigabatrin | 2021 |