pentylenetetrazole has been researched along with pregnanolone in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (31.03) | 18.2507 |
| 2000's | 15 (51.72) | 29.6817 |
| 2010's | 4 (13.79) | 24.3611 |
| 2020's | 1 (3.45) | 2.80 |
| Authors | Studies |
|---|---|
| Belluzzi, JD; Lan, NC; Stein, L; Wieland, S | 1 |
| Crabbe, JC; Finn, DA; Roberts, AJ | 1 |
| Finn, DA; Gee, KW | 1 |
| Barbaccia, ML; Biggio, G; Concas, A; Lener, R; Mostallino, MC; Perra, C; Purdy, RH; Roscetti, G | 1 |
| Bondoux, D; Chapouthier, G; Clément, Y; Launay, JM; Martin, B; Robel, P; Venault, P; Young, J | 1 |
| Finn, DA; Gallaher, EJ; Lotrich, F; Roberts, AJ | 1 |
| Beekman, M; Carter, RB; Dijkstra, D; Gasior, M; Goldberg, SR; Ungard, JT; Witkin, JM | 1 |
| Snead, OC | 1 |
| Banks, MK; Kokate, TG; Magee, T; Rogawski, MA; Yamaguchi, S | 1 |
| Crabbe, JC; Finn, DA; Gallaher, EJ | 1 |
| Beekman, M; Carter, RB; Gasior, M; Ungard, JT; Witkin, JM | 1 |
| Beekman, M; Carter, RB; Dijkstra, D; Gasior, M; Ungard, JT; Witkin, JM | 1 |
| Reddy, DS; Rogawski, MA | 2 |
| Camacho-Arroyo, I; Frye, CA; Manjarrez, J | 1 |
| Carter, RB; Gee, KW; Hogenkamp, DJ; Lan, NC; Vanover, KE | 1 |
| Kim, HY; Reddy, DS; Rogawski, MA | 1 |
| Frye, CA; Muscatiello, NA | 1 |
| France, CP; McMahon, LR | 1 |
| Chopde, CT; Hirani, K; Mittal, N; Ugale, RR | 1 |
| Frye, CA; Rhodes, ME | 1 |
| Haugvicová, R; Kasal, A; Mares, P | 1 |
| Haugvicová, R; Kasal, A; Mares, P; Mikulecká, A | 1 |
| Beadles-Bohling, AS; Crabbe, JC; Finn, DA; Ford, MM; Gililland-Kaufman, KR; Mark, GP; Snelling, C; Tanchuck, MA | 1 |
| Gee, KW; Hogenkamp, DJ; Johnstone, TB; Kanner, R; Tran, MB; Yoshimura, RF | 1 |
| Amiri, M; Kamalinejad, M; Narenjkar, J; Rahimi, H; Sardari, S; Sayyah, M | 1 |
| Ciarlone, SL; Rogawski, MA; Wang, X; Weeber, EJ | 1 |
| Ackley, MA; Althaus, AL; Doherty, JJ; Hammond, RS; Maciag, C; Martinez Botella, G; Robichaud, AJ; Salituro, FG | 1 |
| Ahn, JH; Ahn, SH; Bae, MA; Cho, SH; Hwang, KS; Kan, H; Kim, SS; Lee, BH; Shin, DS; Son, Y; Yang, JY | 1 |
29 other study(ies) available for pentylenetetrazole and pregnanolone
| Article | Year |
|---|---|
Comparative behavioral characterization of the neuroactive steroids 3 alpha-OH,5 alpha-pregnan-20-one and 3 alpha-OH,5 beta-pregnan-20-one in rodents.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Conflict, Psychological; Dose-Response Relationship, Drug; Hypnotics and Sedatives; Isomerism; Male; Mice; Mice, Inbred Strains; Motor Activity; Pentylenetetrazole; Postural Balance; Pregnanolone; Rats; Rats, Sprague-Dawley; Seizures | 1995 |
Neuroactive steroid sensitivity in withdrawal seizure-prone and -resistant mice.
Topics: Alcohol Withdrawal Delirium; Animals; Anticonvulsants; Brain; Dose-Response Relationship, Drug; Electroencephalography; Male; Mice; Pentylenetetrazole; Pregnanolone; Rats; Rats, Inbred Strains; Seizures | 1995 |
The estrus cycle, sensitivity to convulsants and the anticonvulsant effect of a neuroactive steroid.
Topics: Animals; Anticonvulsants; Estrus; Female; Male; Pentylenetetrazole; Pregnanolone; Rats; Rats, Sprague-Dawley; Seizures; Sex Factors | 1994 |
Functional correlation between allopregnanolone and [35S]-TBPS binding in the brain of rats exposed to isoniazid, pentylenetetrazol or stress.
Topics: Animals; Antitubercular Agents; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Convulsants; GABA Modulators; Injections, Intraventricular; Isoniazid; Male; Pentylenetetrazole; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Seizures; Stress, Physiological; Time Factors | 1996 |
A mouse mutant strain highly resistant to methyl beta-carboline-3-carboxylate-induced seizures.
Topics: Animals; Brain Chemistry; Carbolines; Convulsants; Drug Resistance; Evaluation Studies as Topic; Female; Male; Mice; Mice, Mutant Strains; Pentylenetetrazole; Pregnanolone; Pregnenolone; Radioligand Assay; Receptors, GABA-A; Seizures | 1996 |
Genetic differences in behavioral sensitivity to a neuroactive steroid.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Ataxia; Avoidance Learning; Dose-Response Relationship, Drug; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Motor Activity; Muscle Relaxation; Pentylenetetrazole; Pregnanolone; Seizures; Species Specificity; Substance Withdrawal Syndrome | 1997 |
Reversal of behavioral effects of pentylenetetrazol by the neuroactive steroid ganaxolone.
Topics: Animals; Anticonvulsants; Behavior, Animal; Dose-Response Relationship, Drug; Male; Mice; Motor Activity; Pentylenetetrazole; Pregnanolone; Receptors, GABA-A | 1998 |
Ganaxolone, a selective, high-affinity steroid modulator of the gamma-aminobutyric acid-A receptor, exacerbates seizures in animal models of absence.
Topics: Animals; Anticonvulsants; Convulsants; Epilepsy, Absence; GABA Antagonists; Hydroxybutyrates; Male; Pentylenetetrazole; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 1998 |
Finasteride, a 5alpha-reductase inhibitor, blocks the anticonvulsant activity of progesterone in mice.
Topics: Animals; Anticonvulsants; Cholestenone 5 alpha-Reductase; Convulsants; Drug Interactions; Electroshock; Enzyme Inhibitors; Finasteride; Isoenzymes; Male; Mice; Oxidoreductases; Pentylenetetrazole; Pregnanolone; Progesterone; Seizures | 1999 |
Differential change in neuroactive steroid sensitivity during ethanol withdrawal.
Topics: Administration, Inhalation; Alcohol Withdrawal Seizures; Animals; Anticonvulsants; Anxiety; Ataxia; Behavior, Animal; Dose-Response Relationship, Drug; Ethanol; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Muscle Relaxation; Pentylenetetrazole; Pregnanolone; Radioimmunoassay; Species Specificity; Steroids; Substance Withdrawal Syndrome; Time Factors | 2000 |
Acute and chronic effects of the synthetic neuroactive steroid, ganaxolone, against the convulsive and lethal effects of pentylenetetrazol in seizure-kindled mice: comparison with diazepam and valproate.
Topics: Animals; Anticonvulsants; Convulsants; Diazepam; Dose-Response Relationship, Drug; Kindling, Neurologic; Male; Mice; Motor Activity; Pentylenetetrazole; Pregnanolone; Seizures; Stereotypic Movement Disorder; Valproic Acid | 2000 |
Modification of behavioral effects of drugs in mice by neuroactive steroids.
Topics: Animals; Anticonvulsants; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Convulsants; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Mice; Motor Activity; Pentylenetetrazole; Pregnanolone; Pregnenolone; Psychotropic Drugs; Steroids; Synaptic Transmission | 2000 |
Enhanced anticonvulsant activity of ganaxolone after neurosteroid withdrawal in a rat model of catamenial epilepsy.
Topics: Animals; Anticonvulsants; Convulsants; Diazepam; Disease Models, Animal; Enzyme Inhibitors; Epilepsy; Female; Finasteride; Menstruation; Oxidoreductases; Pentylenetetrazole; Pregnanolone; Pseudopregnancy; Rats; Rats, Sprague-Dawley; Seizures; Steroids; Valproic Acid | 2000 |
Infusion of 3alpha,5alpha-THP to the pontine reticular formation attenuates PTZ-induced seizures.
Topics: Animals; Convulsants; Diestrus; Female; Male; Ovariectomy; Pentylenetetrazole; Pregnanolone; Proestrus; Progesterone; Rats; Rats, Long-Evans; Reticular Formation; Seizures | 2000 |
Behavioral characterization of Co 134444 (3alpha-hydroxy-21-(1'-imidazolyl)-3beta-methoxymethyl-5alpha- pregnan-20-one), a novel sedative-hypnotic neuroactive steroid.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Ataxia; Behavior, Animal; Convulsants; Discrimination, Psychological; Dose-Response Relationship, Drug; Drinking; Electroshock; Female; Hypnotics and Sedatives; Male; Mice; Pentylenetetrazole; Postural Balance; Pregnanolone; Punishment; Rats; Rats, Sprague-Dawley; Seizures | 2001 |
Neurosteroid withdrawal model of perimenstrual catamenial epilepsy.
Topics: 20-alpha-Dihydroprogesterone; Adult; Animals; Behavior, Animal; Disease Models, Animal; Disease Susceptibility; Epilepsy; Female; Finasteride; Gonadotropins, Equine; Humans; Menstrual Cycle; Pentylenetetrazole; Pregnanolone; Progesterone; Pseudopregnancy; Rats; Rats, Sprague-Dawley; Receptors, GABA; Steroids; Substance Withdrawal Syndrome | 2001 |
Enhanced anticonvulsant activity of neuroactive steroids in a rat model of catamenial epilepsy.
Topics: Allosteric Regulation; Animals; Anticonvulsants; Benzodiazepinones; Desoxycorticosterone; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; Female; Menstrual Cycle; Pentylenetetrazole; Phenobarbital; Pregnanolone; Pseudopregnancy; Rats; Rats, Sprague-Dawley; Receptors, GABA; Steroids; Substance Withdrawal Syndrome; Valproic Acid | 2001 |
3alpha,5alpha-THP in the raphe magnus attenuates PTZ-induced myoclonic seizures.
Topics: Animals; Cerebral Cortex; Electroencephalography; Epilepsies, Myoclonic; Epilepsy; Estrus; Female; GABA Antagonists; Pentylenetetrazole; Pregnanolone; Progesterone; Raphe Nuclei; Rats; Rats, Long-Evans; Rhombencephalon | 2001 |
Acute and chronic effects of the neuroactive steroid pregnanolone on schedule-controlled responding in rhesus monkeys.
Topics: Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Electroshock; Excitatory Amino Acid Antagonists; Female; Food; GABA Antagonists; GABA Modulators; Ketamine; Macaca mulatta; Male; Pentylenetetrazole; Pregnanolone; Receptors, GABA-A; Reinforcement Schedule; Time Factors; Triazolam | 2002 |
Essentiality of central GABAergic neuroactive steroid allopregnanolone for anticonvulsant action of fluoxetine against pentylenetetrazole-induced seizures in mice.
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Drug Synergism; Fluoxetine; gamma-Aminobutyric Acid; Male; Mice; Pentylenetetrazole; Pregnanolone; Seizures | 2004 |
Estrogen-priming can enhance progesterone's anti-seizure effects in part by increasing hippocampal levels of allopregnanolone.
Topics: Animals; Dose-Response Relationship, Drug; Drug Synergism; Estradiol; Estrogens; Female; Hippocampus; Ovariectomy; Pentylenetetrazole; Pregnanolone; Progesterone; Rats; Rats, Long-Evans; Seizures | 2005 |
Action of two neuroactive steroids against motor seizures induced by pentetrazol in rats during ontogeny.
Topics: Age Factors; Anesthetics; Animals; Animals, Newborn; Convulsants; Desoxycorticosterone; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Pentylenetetrazole; Pregnanolone; Rats; Rats, Wistar | 2006 |
Anticonvulsant action of allopregnanolone in immature rats.
Topics: Age Factors; Anesthetics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Injections, Subcutaneous; Male; Motor Activity; Pentylenetetrazole; Pregnanolone; Rats; Rats, Wistar; Seizures | 2006 |
The neurosteroid environment in the hippocampus exerts bi-directional effects on seizure susceptibility in mice.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Alcohol-Induced Disorders, Nervous System; Animals; Anticonvulsants; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epilepsy; Finasteride; Genetic Predisposition to Disease; Hippocampus; Mice; Mice, Transgenic; Neurons; Pentylenetetrazole; Pregnanolone; Substance Withdrawal Syndrome | 2008 |
Pharmacological profile of a 17β-heteroaryl-substituted neuroactive steroid.
Topics: Androstanes; Animals; Anti-Anxiety Agents; Anticonvulsants; Male; Mice; Motor Activity; Neurotransmitter Agents; Patch-Clamp Techniques; Pentylenetetrazole; Postural Balance; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Xenopus | 2014 |
Anticonvulsant effect of Cicer arietinum seed in animal models of epilepsy: introduction of an active molecule with novel chemical structure.
Topics: Animals; Anticonvulsants; Cicer; Disease Models, Animal; Electroshock; Epilepsy; Male; Mice; Pentylenetetrazole; Plant Extracts; Pregnanolone; Rats; Rats, Wistar; Seeds; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2015 |
Effects of the synthetic neurosteroid ganaxolone on seizure activity and behavioral deficits in an Angelman syndrome mouse model.
Topics: Angelman Syndrome; Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Disease Models, Animal; Female; Hippocampus; Long-Term Potentiation; Male; Maze Learning; Memory, Short-Term; Mice, Knockout; Motor Activity; Pentylenetetrazole; Pregnanolone; Receptors, GABA-A; Seizures; Spatial Memory; Tissue Culture Techniques; Ubiquitin-Protein Ligases | 2017 |
Anticonvulsant profile of the neuroactive steroid, SGE-516, in animal models.
Topics: Action Potentials; Animals; Anticonvulsants; Convulsants; Disease Models, Animal; Electroshock; Fragile X Mental Retardation Protein; gamma-Aminobutyric Acid; Hippocampus; Kindling, Neurologic; Male; Mice; Mice, Knockout; Pentylenetetrazole; Piperidines; Potassium Channel Blockers; Pregnanolone; Rats; Rats, Sprague-Dawley; Seizures | 2017 |
Neurochemical Effects of 4-(2Chloro-4-Fluorobenzyl)-3-(2-Thienyl)-1,2,4-Oxadiazol-5(4H)-One in the Pentylenetetrazole (PTZ)-Induced Epileptic Seizure Zebrafish Model.
Topics: Animals; Anticonvulsants; Antioxidants; Brain; Brain Chemistry; Dihydrotestosterone; Disease Models, Animal; Estradiol; gamma-Aminobutyric Acid; Hydrocortisone; Male; Neuroprotective Agents; Normetanephrine; Oxadiazoles; Oxidative Stress; Pentylenetetrazole; Pregnanolone; Progesterone; Reactive Oxygen Species; Seizures; Serotonin; Zebrafish | 2021 |