Page last updated: 2024-08-17

pentylenetetrazole and naloxone

pentylenetetrazole has been researched along with naloxone in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199013 (38.24)18.7374
1990's6 (17.65)18.2507
2000's5 (14.71)29.6817
2010's8 (23.53)24.3611
2020's2 (5.88)2.80

Authors

AuthorsStudies
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Huković, S; Radivojević, M; Stern, P1
Faase, E; Herz, A; Schulz, R; Wüster, M1
Gylys, JA; Pircio, AW1
De Lima, TC; Rae, GA1
Godlevskiĭ, LS; Karganov, MIu; Kryzhanovskiĭ, GN; Lutsenko, VK; Shandra, AA1
Kraras, CM; Lathers, CM; Tumer, N1
Frey, HH1
Kaneda, H; Kaneto, H; Kawatani, S1
Ciofalo, FR1
Morag, M; Myslobodsky, MS1
Longo, VG; Massotti, M; Sagratella, S1
Alexander, GJ; Chatterjie, N1
Albertson, TE; Lakin, ML; Peterson, SL; Stark, LG; Winters, WD1
Erickson, CK1
Fassos, FF; Mucha, RF; Perl, FM1
Ahmad, I; Lauretti, GR; Pleuvry, BJ1
Becker, A; Brosz, M; Grecksch, G1
Erdtmann-Vourliotis, M; Grecksch, G; Höllt, V; Mayer, P; Riechert, U1
Becker, A; Grecksch, G; Hoellt, V; Schroeder, H; Schroeder, U1
Castro-Souza, C; Coimbra, NC; Garcia-Cairasco, N; Herrero, CF; Nora, JE; Segato, EN; Tedeschi-Filho, W1
Fathi, N; Fathollahi, Y; Ghadami, MR; Omrani, A; Tahmasian, M; Touhidi, A1
Nassiri-Asl, M; Shariati-Rad, S; Zamansoltani, F1
Kumar, M; Rehni, AK; Singh, I1
Fathollahi, Y; Jafarzadeh, Z; Omrani, A; Salmani, ME; Salmanzadeh, F; Semnanian, S1
Asghari-Roodsari, A; Dehpour, AR; Javadi-Paydar, M; Khodadad, TK; Lesani, A; Norouzi, A; Shirkhodaei, M1
Bicalho, Ude O; Coimbra, NC; do Carmo, DR; Felippotti, TT; Fraceto, LF; Grillo, R; Paim, LL; Parada, CA; Stradiotto, NR1
Coimbra, NC; de Freitas, RL; Felippotti, TT1
Alhumayyd, MS; Bukhari, IA; Gilani, AH; Mahesar, AL; Pivac, N1
Mehrzadi, S; Motevalian, M; Pur, SA; Shojaii, A1
Gupta, YK; Prabhakar, P; Reeta, Kh1
Ahmad, N; Akbar, S; Ali, G; Fawad, K; Karim, N; Mahmood, W; Shahid, M; Subhan, F1
Harun, N; Johari, IS; Shoaib, M; Sofian, ZM1
Ali, G; Ayaz, M; Bungau, S; Hassan, SSU; Khan, FA; Khan, Y; Mosa, OF; Nawaz, A; Rahman, K1

Other Studies

34 other study(ies) available for pentylenetetrazole and naloxone

ArticleYear
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
[The inhibition of the effects of morphine by synthetic substance P (author's transl)].
    Experientia, 1976, Oct-15, Volume: 32, Issue:10

    Topics: Amphetamine; Animals; Mice; Morphine; Naloxone; Pentylenetetrazole; Receptors, Opioid; Seizures; Substance P

1976
Selective receptors for beta-endorphin on the rat vas deferens.
    Life sciences, 1979, Feb-26, Volume: 24, Issue:9

    Topics: Animals; Electric Stimulation; Endorphins; In Vitro Techniques; Male; Mice; Naloxone; Pentylenetetrazole; Rats; Receptors, Opioid; Species Specificity; Vas Deferens

1979
Oxilorphan (l-N-cyclopropylmethyl-3,14-dihydroxymorphinan): a new synthetic narcotic antagonist.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 193, Issue:1

    Topics: Animals; Behavior, Animal; Cyclazocine; Dogs; Electroshock; Hot Temperature; Male; Mice; Morphinans; Morphine; Motor Skills; Naloxone; Narcotic Antagonists; Oxymorphone; Pentylenetetrazole; Pupil; Quinones; Rats; Reaction Time; Saimiri

1975
Effects of cold-restraint and swim stress on convulsions induced by pentylenetetrazol and electroshock: influence of naloxone pretreatment.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 40, Issue:2

    Topics: Analgesia; Animals; Cold Temperature; Electroshock; Male; Mice; Naloxone; Pain Measurement; Pentylenetetrazole; Restraint, Physical; Seizures; Stress, Psychological; Swimming

1991
[Effect of brain extracts from rats subjected to korazol kindling on generalized epileptic activity].
    Biulleten' eksperimental'noi biologii i meditsiny, 1989, Volume: 107, Issue:3

    Topics: Animals; Brain; Drug Interactions; Epilepsy; Kindling, Neurologic; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Naloxone; Pentylenetetrazole; Peptides; Picrotoxin; Rats; Rats, Inbred Strains

1989
The effect of intracerebroventricular D-ALA2 methionine enkephalinamide and naloxone on cardiovascular parameters in the cat.
    Life sciences, 1988, Volume: 43, Issue:26

    Topics: Animals; Blood Pressure; Cats; Cerebral Ventricles; Enkephalin, Methionine; Epilepsy; Heart; Heart Conduction System; Heart Rate; Injections, Intraventricular; Models, Neurological; Naloxone; Pentylenetetrazole; Reference Values

1988
Endogenous opioids and post-ictal increase in seizure threshold in Mongolian gerbils.
    Epilepsy research, 1987, Volume: 1, Issue:2

    Topics: Animals; Electric Stimulation; Endorphins; Gerbillinae; Morphine; Naloxone; Naltrexone; Pentylenetetrazole; Seizures

1987
Differentiation of alcohol and barbital physical dependence.
    Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology, 1986, Volume: 6, Issue:2

    Topics: Animals; Barbital; Barbiturates; Diazepam; Ethanol; Ethosuximide; Male; Mice; Morphine; Naloxone; Pentylenetetrazole; Phenytoin; Substance Withdrawal Syndrome

1986
Effects of some narcotics and antagonists on synaptosomal 3 H-norepinephrine uptake.
    Life sciences. Pt. 1: Physiology and pharmacology, 1972, Jun-15, Volume: 11, Issue:12

    Topics: Animals; Brain; Codeine; In Vitro Techniques; Methadone; Morphine; Nalorphine; Naloxone; Narcotics; Nerve Endings; Nerve Tissue Proteins; Norepinephrine; Pentobarbital; Pentylenetetrazole; Protein Binding; Rabbits; Synaptic Vesicles; Synaptosomes; Thebaine

1972
Pharmacologic analysis of sodium valproate-induced suppression of secondary components of visual evoked potentials in albino rats.
    Pharmacology, biochemistry, and behavior, 1981, Volume: 15, Issue:5

    Topics: Animals; Benzodiazepinones; Convulsants; Drug Interactions; Evoked Potentials, Visual; Female; gamma-Aminobutyric Acid; Male; Naloxone; Pentylenetetrazole; Photic Stimulation; Picrotoxin; Rats; Synaptic Transmission; Time Factors; Valproic Acid

1981
Convulsant drugs and changes in the electrical activity of the brain: an investigation of the effects of opioids on chemoconvulsions.
    Progress in clinical and biological research, 1983, Volume: 124

    Topics: Animals; Brain; Convulsants; Electroencephalography; Electrophysiology; GABA Antagonists; Morphine; Naloxone; Narcotics; Nikethamide; Pentylenetetrazole; Seizures; Strychnine; Synaptic Transmission

1983
Naloxone-6-spirohydantoin: a new non-toxic compound with anticonvulsive properties.
    Neuropharmacology, 1983, Volume: 22, Issue:9

    Topics: Animals; Anticonvulsants; Chemical Phenomena; Chemistry; Electroshock; Hydantoins; Male; Mice; Naloxone; Pentylenetetrazole; Seizures

1983
The anticonvulsant properties of melatonin on kindled seizures in rats.
    Neuropharmacology, 1981, Volume: 20, Issue:1

    Topics: Amygdala; Animals; Anticonvulsants; Diazepam; Electric Stimulation; Male; Melatonin; Naloxone; Pentylenetetrazole; Phenobarbital; Rats; Seizures

1981
Requirements for an ideal alcohol antagonist.
    Advances in experimental medicine and biology, 1980, Volume: 126

    Topics: Alcoholic Intoxication; Animals; Caffeine; Cats; Dextroamphetamine; Disease Models, Animal; Dogs; Ethanol; gamma-Aminobutyric Acid; Humans; Maleates; Naloxone; Pentylenetetrazole; Rabbits; Strychnine

1980
Withdrawal-like effects of pentylenetetrazol and valproate in the naive organism: a model of motivation produced by opiate withdrawal?
    Drug and alcohol dependence, 1995, Volume: 39, Issue:1

    Topics: Animals; Avoidance Learning; Conditioning, Classical; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Morphine Dependence; Motivation; Naloxone; Neurologic Examination; Opioid-Related Disorders; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Taste; Valproic Acid

1995
The activity of opioid analgesics in seizure models utilizing N-methyl-DL-aspartic acid, kainic acid, bicuculline and pentylenetetrazole.
    Neuropharmacology, 1994, Volume: 33, Issue:2

    Topics: Analgesics, Opioid; Animals; Anticonvulsants; Bicuculline; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Kainic Acid; Male; Mice; N-Methylaspartate; Naloxone; Pentylenetetrazole; Seizures

1994
Naloxone ameliorates the learning deficit induced by pentylenetetrazol kindling in rats.
    The European journal of neuroscience, 1994, Sep-01, Volume: 6, Issue:9

    Topics: Animals; Avoidance Learning; Dose-Response Relationship, Drug; Kindling, Neurologic; Learning Disabilities; Male; Naloxone; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Sodium Chloride

1994
Pentylenetetrazole (PTZ)-induced c-fos expression in the hippocampus of kindled rats is suppressed by concomitant treatment with naloxone.
    Brain research, 1998, May-11, Volume: 792, Issue:2

    Topics: Amygdala; Animals; Convulsants; Dentate Gyrus; Epilepsy; Gene Expression; Gyrus Cinguli; In Situ Hybridization; Kindling, Neurologic; Male; Naloxone; Narcotic Antagonists; Opioid Peptides; Pentylenetetrazole; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, Opioid; RNA, Messenger; Septal Nuclei

1998
The effect of pentylenetetrazol kindling on synaptic mechanisms of interacting glutamatergic and opioid system in the hippocampus of rats.
    Brain research, 1998, Nov-16, Volume: 811, Issue:1-2

    Topics: Animals; Convulsants; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hippocampus; In Vitro Techniques; Kindling, Neurologic; Male; Naloxone; Naltrexone; Narcotic Antagonists; Pentylenetetrazole; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, Opioid; Seizures; Synapses

1998
Post-ictal analgesia: involvement of opioid, serotoninergic and cholinergic mechanisms.
    Brain research, 2001, Jan-12, Volume: 888, Issue:2

    Topics: Analgesia; Animals; Atropine; Convulsants; Disease Models, Animal; Injections, Intraperitoneal; Ketanserin; Methysergide; Motor Activity; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Pain Measurement; Pentylenetetrazole; Rats; Rats, Wistar; Reaction Time; Reflex; Seizures; Serotonin Antagonists

2001
Naloxone improves impairment of spatial performance induced by pentylenetetrazol kindling in rats.
    Neuroscience, 2007, Mar-30, Volume: 145, Issue:3

    Topics: Animals; Kindling, Neurologic; Kinetics; Male; Naloxone; Pentylenetetrazole; Rats; Rats, Inbred Strains; Space Perception

2007
Anticonvulsant effects of aerial parts of Passiflora incarnata extract in mice: involvement of benzodiazepine and opioid receptors.
    BMC complementary and alternative medicine, 2007, Aug-08, Volume: 7

    Topics: Animals; Anticonvulsants; Antidotes; Convulsants; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy, Absence; Flumazenil; Injections, Intraperitoneal; Male; Mice; Mice, Inbred BALB C; Naloxone; Narcotic Antagonists; Passiflora; Pentylenetetrazole; Phytotherapy; Plant Components, Aerial; Plant Extracts; Receptors, GABA-A; Receptors, Opioid; Sodium Chloride; Treatment Outcome

2007
Tramadol-induced seizurogenic effect: a possible role of opioid-dependent gamma-aminobutyric acid inhibitory pathway.
    Basic & clinical pharmacology & toxicology, 2008, Volume: 103, Issue:3

    Topics: Amines; Analgesics, Opioid; Animals; Cyclohexanecarboxylic Acids; GABA Agents; Gabapentin; gamma-Aminobutyric Acid; Mice; Mice, Inbred Strains; Naloxone; Narcotic Antagonists; Pentylenetetrazole; Receptors, GABA; Receptors, Opioid; Seizures; Tramadol

2008
Morphine dependence increases the response to a brief pentylenetetrazol administration in rat hippocampal CA1 in vitro.
    Epilepsia, 2009, Volume: 50, Issue:4

    Topics: Animals; Convulsants; Disease Models, Animal; Drug Interactions; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Neural Pathways; Pentylenetetrazole; Rats; Rats, Inbred Strains; Statistics, Nonparametric; Substance Withdrawal Syndrome

2009
Involvement of the nitric oxide pathway in the anticonvulsant effect of tramadol on pentylenetetrazole-induced seizures in mice.
    Epilepsy & behavior : E&B, 2010, Volume: 19, Issue:3

    Topics: Analysis of Variance; Animals; Anticonvulsants; Arginine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Male; Mice; Mice, Inbred Strains; Naloxone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Seizures; Signal Transduction; Time Factors; Tramadol

2010
Effect of a nanostructured dendrimer-naloxonazine complex on endogenous opioid peptides μ1 receptor-mediated post-ictal antinociception.
    Nanomedicine : nanotechnology, biology, and medicine, 2011, Volume: 7, Issue:6

    Topics: Analgesia; Animals; Dendrimers; Drug Carriers; Male; Naloxone; Narcotic Antagonists; Pentylenetetrazole; Polypropylenes; Rats; Rats, Wistar; Receptors, Opioid, mu; Seizures

2011
Endogenous opioid peptide-mediated neurotransmission in central and pericentral nuclei of the inferior colliculus recruits μ1-opioid receptor to modulate post-ictal antinociception.
    Neuropeptides, 2012, Volume: 46, Issue:1

    Topics: Animals; Inferior Colliculi; Male; Naloxone; Opioid Peptides; Pentylenetetrazole; Rats; Rats, Wistar; Receptors, Opioid, mu; Seizures; Synaptic Transmission

2012
The analgesic and anticonvulsant effects of piperine in mice.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2013, Volume: 64, Issue:6

    Topics: Acetic Acid; Alkaloids; Analgesics; Animals; Anticonvulsants; Benzodioxoles; Hot Temperature; Male; Mice; Naloxone; Narcotic Antagonists; Pain; Pentylenetetrazole; Picrotoxin; Piper nigrum; Piperidines; Polyunsaturated Alkamides; Seizures

2013
Anticonvulsant Activity of Hydroalcoholic Extract of Citrullus colocynthis Fruit: Involvement of Benzodiazepine and Opioid Receptors.
    Journal of evidence-based complementary & alternative medicine, 2016, Volume: 21, Issue:4

    Topics: Animals; Anticonvulsants; Benzodiazepines; Citrullus colocynthis; Flavonoids; Flumazenil; Fruit; Herb-Drug Interactions; Male; Medicine, Arabic; Mice; Naloxone; Pentylenetetrazole; Plant Extracts; Receptors, Opioid; Seizures

2016
Anticonvulsant activity of the antidepressant drug, tianeptine, against pentylenetetrazole-induced seizures mitigates cognitive impairment in rats.
    Behavioural pharmacology, 2016, Volume: 27, Issue:7

    Topics: Animals; Anticonvulsants; Antidepressive Agents, Tricyclic; Avoidance Learning; Behavior, Animal; Cognitive Dysfunction; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutathione; Male; Malondialdehyde; Maze Learning; Naloxone; Oxidative Stress; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Thiazepines

2016
6-Methoxyflavanone attenuates mechanical allodynia and vulvodynia in the streptozotocin-induced diabetic neuropathic pain.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 84

    Topics: Amines; Animals; Computer Simulation; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Female; Flavanones; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Models, Molecular; Naloxone; Neuralgia; Nociception; Pentylenetetrazole; Rats, Sprague-Dawley; Receptors, GABA; Streptozocin; Toxicity Tests, Acute; Vulvodynia

2016
Pentylenetetrazol-like stimulus is not produced following naloxone-precipitated mitragynine withdrawal in rats.
    Psychopharmacology, 2021, Volume: 238, Issue:11

    Topics: Animals; Naloxone; Pentylenetetrazole; Rats; Secologanin Tryptamine Alkaloids; Substance Withdrawal Syndrome

2021
Efficacy of 2-Hydroxyflavanone in Rodent Models of Pain and Inflammation: Involvement of Opioidergic and GABAergic Anti-Nociceptive Mechanisms.
    Molecules (Basel, Switzerland), 2022, Aug-25, Volume: 27, Issue:17

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Cisplatin; Disease Models, Animal; Edema; Flavanones; Gabapentin; Hyperalgesia; Inflammation; Naloxone; Neuralgia; Pentylenetetrazole; Rodentia

2022