Page last updated: 2024-08-17

pentylenetetrazole and hydantoins

pentylenetetrazole has been researched along with hydantoins in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199018 (78.26)18.7374
1990's2 (8.70)18.2507
2000's1 (4.35)29.6817
2010's1 (4.35)24.3611
2020's1 (4.35)2.80

Authors

AuthorsStudies
Ganz, AJ; Pfirrmann, RW; Waser, PG1
O'Dea, MH; Reinhard, JF; Samour, CM; Vida, JA1
Alexander, GJ; Chatterjie, N2
Cortes, S; Kohn, H; Liao, ZK; Watson, D1
Forrest, TP; Gilroy, ML; Vohra, MM; Yung, DK1
Rümke, CL1
Natarajan, PN1
Blackburn, WH; Napoli, MD; Wallin, RF1
Belsky, I; Gertner, D; Zilkha, A1
Krimsley, V; Shaffer, JW; Steinberg, E; Winstead, WB1
Andrews, PR1
Alberty, JE; Enebäck, C1
Bartels, E; Rosenberg, P1
Alexander, GJ; Chatterjie, N; Sinha, B1
Avendaño, MC; Ballesteros, P; Cañadas, S; González, MP1
Karolak-Wojciechowska, J; Kiec-Kononowicz, K; Kwiatkowski, W1
Kwon, CH; Sun, ZY; Wurpel, ND1
Kohn, H; LeTiran, A; Stables, JP1
FROMMEL, E; GOLD, P; RADOUCO, C1
ARAI, S; GOTO, Y; SEKIBA, K; TAEN, S1
Byrtus, H; Kamiński, K; Karolak-Wojciechowska, J; Obniska, J; Pawłowski, M; Szczesio, M1
Abd-Allah, WH; Aboul-Enein, MN; Aboutabl, ME; El-Azzouny, AA; Hassan, RM1

Other Studies

23 other study(ies) available for pentylenetetrazole and hydantoins

ArticleYear
[Development of new antiepileptics. II. Anticonvulsant effect of hydantoin derivatives].
    Arzneimittel-Forschung, 1977, Volume: 27, Issue:11

    Topics: Analgesics; Animals; Anticonvulsants; Electroshock; Hydantoins; Hypnotics and Sedatives; Mice; Mice, Inbred ICR; Motor Activity; Pentylenetetrazole

1977
Anticonvulsants. 5. Derivatives of 5-ethyl-5-phenylhydantoin and 5,5-diphenylhydantoin.
    Journal of medicinal chemistry, 1975, Volume: 18, Issue:4

    Topics: Animals; Anticonvulsants; Depression, Chemical; Electroshock; Hydantoins; Lethal Dose 50; Male; Mice; Motor Activity; Pentylenetetrazole; Phenytoin; Reflex; Seizures; Sleep

1975
Anticonvulsant properties of spirohydantoins derived from optical isomers of camphor.
    Neurochemical research, 1986, Volume: 11, Issue:12

    Topics: Animals; Anticonvulsants; Camphor; Double-Blind Method; Hydantoins; Male; Mice; Pentylenetetrazole; Seizures; Stereoisomerism

1986
Effect of structural modification of the hydantoin ring on anticonvulsant activity.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:5

    Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroshock; Hydantoins; Male; Mice; Motor Activity; Pentylenetetrazole; Postural Balance; Structure-Activity Relationship

1985
Alkylation reactions of hydantoins and succinimides.
    Journal of pharmaceutical sciences, 1973, Volume: 62, Issue:11

    Topics: Alkylation; Animals; Anticonvulsants; Benzyl Compounds; Chemical Phenomena; Chemistry; Ethosuximide; Hydantoins; Magnetic Resonance Spectroscopy; Male; Mice; Nitro Compounds; Pentylenetetrazole; Phenytoin; Spectrophotometry, Infrared; Succinimides

1973
Increased susceptibility of mice to seizures after some anticonvulsant drugs.
    European journal of pharmacology, 1967, Volume: 1, Issue:5

    Topics: Animals; Anticonvulsants; Bemegride; Central Nervous System Stimulants; Drug Synergism; Electroshock; Ethionine; Female; Hydantoins; Male; Methods; Mice; Oxazines; Pentylenetetrazole; Phenobarbital; Phenytoin; Primidone; Rats; Seizures; Trimethadione

1967
Anticonvulsant drugs. Benzylation of hydantoins using strong anion exchange resin.
    Acta pharmaceutica Suecica, 1971, Volume: 8, Issue:5

    Topics: Animals; Anticonvulsants; Benzyl Compounds; Hydantoins; Ion Exchange Resins; Lethal Dose 50; Mice; Pentylenetetrazole

1971
Pharmacologic interactions of albutoin with other anticonvulsant drugs.
    The Journal of pharmacology and experimental therapeutics, 1970, Volume: 174, Issue:2

    Topics: Animals; Anticonvulsants; Drug Synergism; Electroshock; Hydantoins; Male; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Seizures; Trimethadione

1970
Silicon-containing barbiturates.
    Journal of medicinal chemistry, 1968, Volume: 11, Issue:1

    Topics: Animals; Barbiturates; Behavior, Animal; Electroshock; Hydantoins; Male; Methods; Mice; Pentylenetetrazole; Phenobarbital; Propylene Glycols; Silicon; Sulfur

1968
Substitution in the hydantoin ring. VII. N-3-Propionic acid and its ethyl ester and N-3-(2-cyanoethyl) derivatives.
    Journal of medicinal chemistry, 1968, Volume: 11, Issue:3

    Topics: Alkylation; Animals; Drug Synergism; Electroshock; Hexobarbital; Hydantoins; Infrared Rays; Magnetic Resonance Spectroscopy; Male; Mice; Motor Activity; Pentylenetetrazole; Phenytoin; Propionates; Spectrum Analysis; Ultraviolet Rays

1968
Molecular orbital calculations on anticonvulsant drugs.
    Journal of medicinal chemistry, 1969, Volume: 12, Issue:5

    Topics: Animals; Anticonvulsants; Barbiturates; Chemical Phenomena; Chemistry; Electroshock; Hydantoins; Hydrogen; Methods; Mice; Pentylenetetrazole; Pyrrolidines; Rats

1969
Synthesis and anticonvulsive properties of substituted 5-phenyl-5-benzyl-hydantoins.
    Arzneimittel-Forschung, 1965, Volume: 15, Issue:10

    Topics: Animals; Anticonvulsants; Chemical Phenomena; Chemistry; Hydantoins; In Vitro Techniques; Infusions, Parenteral; Injections, Intravenous; Injections, Subcutaneous; Mice; Pentylenetetrazole

1965
Drug effects on the spontaneous electrical activity of the squid giant axon.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 155, Issue:3

    Topics: Acetylcholine; Action Potentials; Animals; Anticonvulsants; Atropine; Axons; Barbiturates; Bromides; Chloroform; Chlorpheniramine; Chlorpromazine; Curare; Dopamine; Electrophysiology; Ethanol; Ethers; Evoked Potentials; Hydantoins; Mollusca; Muscles; Nortropanes; Parasympatholytics; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Procaine; Serotonin; Strychnine; Tetracaine; Tremorine; Trihexyphenidyl; Trimethadione

1967
A spirohydantoin derivative of dimethoxytetrahydronaphthalene: an experimental anticonvulsant.
    Neurochemical research, 1984, Volume: 9, Issue:4

    Topics: Animals; Anticonvulsants; Electroshock; Exploratory Behavior; Hydantoins; Male; Mice; Motor Activity; Pentylenetetrazole; Seizures

1984
Naloxone-6-spirohydantoin: a new non-toxic compound with anticonvulsive properties.
    Neuropharmacology, 1983, Volume: 22, Issue:9

    Topics: Animals; Anticonvulsants; Chemical Phenomena; Chemistry; Electroshock; Hydantoins; Male; Mice; Naloxone; Pentylenetetrazole; Seizures

1983
Effect of diphenylhydantoin, granatane-3-spiro-5'-hydantoin and leptazol on mouse brain glutamate dehydrogenase, urea and ammonia levels in brain.
    Revista espanola de fisiologia, 1981, Volume: 37, Issue:2

    Topics: Ammonia; Animals; Brain; Drug Interactions; Glutamate Dehydrogenase; Hydantoins; Mice; Mice, Inbred ICR; Pentylenetetrazole; Phenytoin; Urea

1981
Structural and electronic conditions for anticonvulsant activity of bicyclic hydantoin derivatives.
    Die Pharmazie, 1995, Volume: 50, Issue:2

    Topics: Anticonvulsants; Crystallography, X-Ray; Electroshock; Hydantoins; Pentylenetetrazole; Phenytoin; Stereoisomerism; Structure-Activity Relationship

1995
Structure-activity study of 5-substituted 1-carbobenzoxy-2-iminohydantoins as potential anticonvulsant agents.
    Journal of medicinal chemistry, 1994, Sep-02, Volume: 37, Issue:18

    Topics: Animals; Electroshock; Hydantoins; Imines; Male; Mice; Pentylenetetrazole; Postural Balance; Rats; Structure-Activity Relationship

1994
Functionalized amino acid anticonvulsants: synthesis and pharmacological evaluation of conformationally restricted analogues.
    Bioorganic & medicinal chemistry, 2001, Volume: 9, Issue:10

    Topics: Amino Acids; Animals; Anticonvulsants; Catalysis; Crystallography, X-Ray; Cyclization; Drug Design; Hydantoins; Lactams; Magnetic Resonance Spectroscopy; Male; Mice; Molecular Conformation; Molecular Structure; Neuroblastoma; Pentylenetetrazole; Phenobarbital; Phenytoin; Proline; Rats; Seizures; Sodium Channels; Stereoisomerism; Structure-Activity Relationship; Tetrazoles; Tumor Cells, Cultured

2001
[Analysis of diphenylhydantoin in electroshock and metrazol shock].
    Medecine et hygiene, 1952, Oct-19, Volume: 10, Issue:228

    Topics: Convulsive Therapy; Electroshock; Hydantoins; Pentylenetetrazole; Phenytoin; Shock

1952
[ANTIEPILEPTIC ACTIVITIES OF A NEW COMPOUND, ETHOXYCARBODIPHENYLHYDANTOIN].
    No to shinkei = Brain and nerve, 1964, Volume: 16

    Topics: Animals; Anticonvulsants; Hydantoins; Mice; Pentylenetetrazole; Pharmacology; Rats; Research; Seizures

1964
Design, synthesis, and anticonvulsant activity of new N-Mannich bases derived from spirosuccinimides and spirohydantoins.
    Bioorganic & medicinal chemistry, 2010, Aug-15, Volume: 18, Issue:16

    Topics: Animals; Anticonvulsants; Electroshock; Hydantoins; Male; Mannich Bases; Mice; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures; Sodium Channels; Spiro Compounds; Succinimides

2010
Design and synthesis of novel parabanic acid derivatives as anticonvulsants.
    Bioorganic chemistry, 2020, Volume: 94

    Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Drug Design; Hepatocytes; Hydantoins; Male; Mice; Models, Molecular; Molecular Structure; Pentylenetetrazole; Seizures; Structure-Activity Relationship

2020