Page last updated: 2024-08-17

pentylenetetrazole and hexobarbital

pentylenetetrazole has been researched along with hexobarbital in 80 studies

Research

Studies (80)

Timeframe	Studies, this research(%)	All Research%
pre-1990	74 (92.50)	18.7374
1990's	3 (3.75)	18.2507
2000's	2 (2.50)	29.6817
2010's	1 (1.25)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
de Angelis, L; Traversa, U; Vertua, R	3
Ager, IR; Danswan, GW; Harrison, DR; Kay, DP; Kennewell, PD; Taylor, JB	1
Fujimoto, Y; Nakata, C; Ogura, M; Shika, K; Tamada, T	1
Cuparencu, B; Safta, L	1
Ghazal, A; Islam, SI; Makar, AB	1
Arioli, V; Cavalleri, B; Diena, A; Pizzocheri, F; Volpe, G	1
Garibova, TL; Klygul', TA; Vikhliaev, IuI	1
Barczyńska, J; Felsztyńska, J; Kedzierska, L; Wilimowski, M; Witkowska, M; Wojewódzki, W	1
Alioto, RL; Mir, GN; Riley, RL; Rowles, GS; Sperow, JW; Yelnosky, J	1
Kharalambieva, M; Micheva, M; Raĭnova, L; Staneva-Stoĭcheva, D	1
Contreras, E; Quijada, L; Tamayo, L	1
Hata, T; Kita, T; Miyake, Y; Okage, T	1
Becker, A; Grecksch, G; Matthies, H; Ruethrich, HL; Schneider, R	1
Baldoli, E; Bianchi, G; Corsico, N; Di Francesco, GF	1
Ambrogi, V; Grandolini, G; Rossi, C; Tiralti, MC	1
Hikino, H; Kasahara, Y; Konno, C; Ogata, K	1
Chalabian, ZhA	1
Asami, Y; Hirohashi, T; Inaba, S; Otsuka, M; Yamamoto, H	1
Grossmann, W; Jurna, I; Theres, C	1
Goodsell, EB; Stein, HH; Wenzke, KJ	1
Gillette, JR; Stripp, B	1
Myschetzky, A	1
Waring, WS; Whittle, BA	1
Ammon, HP; Estler, CJ	1
Banci, F; Tubaro, E	1
Kimura, R; Murata, T	1
Babbini, M; Torrielli, MV	1
Gogerty, JH; Iorio, LC; Kerestan, SP; Ryan, EA	1
Absil, J; Buchel, L	1
Georgiev, V; Petkov, V; Petkova, B	1
de Angelis, L; Predominato, M; Vertua, R	1
De Souza, NJ; Desai, PD; Dohadwalla, AN; Kohl, H	1
Saito, C; Sakai, S; Takagi, H; Yamamoto, H; Yukawa, Y	1
Atkinson, ER; Russ, PL; Tucker, MA	1
Del Rio, J; Fernández-Tomé, MP; Madroñero, R; Vega, S	1
Inoki, R; Iwatsubo, K; Shigenaga, Y	1
Barfknecht, CF; Engelbrecht, JA; Long, JP; Nichols, DE	1
Leonard, BE	1
Casadio, S; Marazzi-Uberti, E; Minoli, G	1
Murai, S; Oizumi, Y; Ozawa, H; Seto, S	1
Furukawa, T; Hanabusa, Y; Kushiku, K; Ono, N	1
Oester, YT; Prabhu, VG	1
Ratcliffe, F	1
Babbini, M; De Marchi, F; Montanaro, N; Strocchi, P; Torrielli, MV	1
Fukuda, T; Katsuda, N; Tanaka, K	1
Adronati, SA; Klygul', TA; Prokudin, VN; Vikhliaev, IuI	1
Krimsley, V; Shaffer, JW; Steinberg, E; Winstead, WB	1
Burgison, RM; Dietz, AJ	1
Barry, H; Buckley, JP; Manian, AA; Watzman, N	1
Melson, F	1
Pelczarska, A	1
Haas, H; Jantos, W	1
Furgiuele, AR; High, JP; Horovitz, ZP	1
Casadio, S; Coppi, G; Marazziùberti, E; Pala, G	1
Prastowski, W; Zak, A	1
Rudzik, AD; Wagner, ER	1
Kruse, H; Rössner, M; Siegemund, G	1
Kruszewska, A; Langwiński, R	1
Fischer, W; Müller, M; Schilling, E; Schmiedel, R	1
Kamińska, A; Kusowska, J; Mazur, M; Szadowska, A; Winer, A	1
Bluth, R	1
Flagmeyer, I; Gebert, I; van der Staay, FJ	1
Dziuba, J; Kleinrok, Z; Saczonek, J; Sieklucka-Dziuba, M	1
Antkiewicz-Michaluk, L; Dybala, I; Fidecka, S; Koziol, AE; Lipkowski, J; Matosiuk, D	1
FRIGYESI, G; ZADOR, I	1
HAPKE, HJ	1
BELLARE, RA; DELIWALA, CV; SHETH, UK; VAZ, A	1
FREY, HH; KAMPMANN, E	1
ARUSHANIAN, EB; SHAPAVALOV, AI	1
DEJONGE, MC; DONNER, R; FUNCKE, AB; HARMS, AF; MULDER, D; NAUTA, WT; RUEMKE, CL; TERSTEEGE, HM	1
BENFEY, BG; VARMA, DR	1
SIMIONOVICI, M; WINTER, D	1
MUELLER, M; SCHMIEDEL, R	1
BEGUIN, M; FAMILY, S; FLEURY, C; FROMMEL, E; LEDEBUR, IV	1
WOJEWODZKI, W	1
LECHAT, P; MAGET, E; STREICHENBERGER, G	1
Doi, N; Furuta, S; Imaizumi, M; Nakagawa, T; Shimada, O; Ukai, K; Watanabe, J	1
Can, OD; Ozkay, UD	1

Other Studies

80 other study(ies) available for pentylenetetrazole and hexobarbital

Article	Year
On the hypnogenic and anticonvulsant activities of demethyldiazepam and chlordemethyldiazepam: time-effect relations. The Journal of pharmacy and pharmacology, 1977, Volume: 29, Issue:8 Topics: Animals; Anticonvulsants; Chlorprothixene; Diazepam; Female; Hexobarbital; Hypnotics and Sedatives; Mice; Nordazepam; Pentylenetetrazole; Time Factors	1977
Central nervous system activity of a novel class of annelated 1,4-benzodiazepines, aminomethylene-2,4-dihydro-1H-imidazo[1,2-a][1,4]benzodiazepin-1-ones. Journal of medicinal chemistry, 1977, Volume: 20, Issue:8 Topics: Aggression; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepinones; Chlorprothixene; Drug Synergism; Electroshock; Hexobarbital; Humans; Male; Mice; Motor Activity; Pentylenetetrazole; Strychnine	1977
[Inhibitory effects of methyl o-(4-hydroxy-3-methoxycinnamoyl) reserpate (CD-3400) on the central nervous system (author's transl)]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1977, Volume: 73, Issue:7 Topics: Agonistic Behavior; Animals; Avoidance Learning; Blepharoptosis; Body Temperature; Cats; Central Nervous System; Cooperative Behavior; Depression, Chemical; Drug Synergism; Electroencephalography; Female; Hexobarbital; Male; Methamphetamine; Mice; Morphine; Motor Activity; Pentylenetetrazole; Rats; Reserpine; Seizures; Serotonin	1977
Some central nervous actions of centrophenoxine (Meclofenoxat) in animals. Acta biologica et medica Germanica, 1978, Volume: 37, Issue:8 Topics: Anesthesia; Animals; Antidepressive Agents; Behavior, Animal; Central Nervous System Stimulants; Drug Synergism; Electroshock; Female; Glycolates; Hexobarbital; Male; Meclofenoxate; Pentylenetetrazole; Rats; Seizures	1978
A comparative study of the effect of some steroid hormones on the response of rats to other drugs. Die Pharmazie, 1975, Volume: 30, Issue:9 Topics: Adrenal Cortex Hormones; Animals; Cortisone; Dehydroepiandrosterone; Desoxycorticosterone; Dexamethasone; Drug Interactions; Enzyme Activation; Estradiol; Female; Hexobarbital; Liver; Male; Methandrostenolone; Pentylenetetrazole; Prednisolone; Progesterone; Rats; Sleep; Testosterone; Time Factors	1975
Synthesis and biological activity of new 2-nitroimidazole derivatives. Journal of medicinal chemistry, 1978, Volume: 21, Issue:8 Topics: Animals; Antitrichomonal Agents; Clostridium perfringens; Drug Interactions; Hexobarbital; Male; Mice; Microbial Sensitivity Tests; Mycoplasma; Nitroimidazoles; Pentylenetetrazole; Sleep; Staphylococcus aureus; Streptococcus pyogenes; Strychnine; Trichomonas Infections; Trichomonas vaginalis	1978
[Experimental characteristics of the spectrum of pharmacologic activity of the tranquilizer lorazepam]. Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1975, Volume: 75, Issue:3 Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Chlordiazepoxide; Conflict, Psychological; Diazepam; Drug Synergism; Hexobarbital; Humans; Hypnotics and Sedatives; Inhibition, Psychological; Mice; Muscle Relaxants, Central; Nicotine; Nitrazepam; Pentylenetetrazole; Rats; Reaction Time	1975
Central action of new derivatives of tetrahydropirimidinedione-4,6. Archivum immunologiae et therapiae experimentalis, 1979, Volume: 27, Issue:3 Topics: Amphetamine; Analgesics; Animals; Brain; Chloral Hydrate; Drug Synergism; Female; Furans; Hexobarbital; Levodopa; Male; Mice; Movement; Pentylenetetrazole; Pyrimidinones; Reserpine; Seizures; Sleep	1979
Effects of lidamidine hydrochloride (WHR-1142A), a novel antidiarrheal agent on the cardiovascular and central nervous systems. Arzneimittel-Forschung, 1978, Volume: 28, Issue:8a Topics: Amidines; Amphetamine; Animals; Antidiarrheals; Blood Pressure; Cardiac Output; Central Nervous System; Dogs; Ethanol; Flurazepam; Guinea Pigs; Heart Rate; Hemodynamics; Hexobarbital; In Vitro Techniques; Male; Mice; Myocardial Contraction; Pentylenetetrazole; Vascular Resistance	1978
[Neurophoarmacologic profile of an aminotetraline derivative]. Eksperimentalna meditsina i morfologiia, 1977, Volume: 16, Issue:4 Topics: Amphetamine; Analgesics; Animals; Apomorphine; Central Nervous System; Drug Interactions; Hexobarbital; Mice; Morphine; Motor Activity; Muscle Tonus; Naphthols; Nervous System; Pentylenetetrazole; Piperazines; Rats; Reserpine; Strychnine	1977
Sensitivity changes to morphine and other drugs induced by cholinergic blockade. Archives internationales de pharmacodynamie et de therapie, 1975, Volume: 214, Issue:2 Topics: Amphetamine; Analgesics; Animals; Arecoline; Atropine; Drug Tolerance; Female; Hexobarbital; Humans; Mice; Morphine; Parasympatholytics; Pentylenetetrazole; Reserpine; Sleep; Substance Withdrawal Syndrome; Time Factors	1975
[Relation of time of administration of drugs to their acute toxicity to experimental animals]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1975, Volume: 71, Issue:1 Topics: Animals; Aspartic Acid; Chlorpromazine; Circadian Rhythm; Convulsants; Hexobarbital; Male; Mice; Pentylenetetrazole; Picrotoxin; Strychnine	1975
Pharmacological effects on two inbred substrains of AB mice. Pharmacology, biochemistry, and behavior, 1991, Volume: 38, Issue:2 Topics: Aggression; Animals; Behavior, Animal; Diazepam; Dose-Response Relationship, Drug; Haloperidol; Hexobarbital; Mice; Mice, Inbred Strains; Neurotransmitter Agents; Pentylenetetrazole; Species Specificity	1991
Pharmacological studies of N-(2,5-dimethyl-1H-pyrrol-1-yl)-6-(4-morpholinyl)-3-pyridazinamine hydrochloride (MDL-899), a new long-acting antihypertensive vasodilator. Arzneimittel-Forschung, 1985, Volume: 35, Issue:5 Topics: Administration, Oral; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Avoidance Learning; Dogs; Hemodynamics; Hexobarbital; Hypertension, Renal; Indomethacin; Injections, Intravenous; Male; Pentylenetetrazole; Postural Balance; Pyridazines; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Sleep; Species Specificity; Vasodilator Agents	1985
Studies on annelated 1,4-benzothiazines and 1,5-benzothiazepines. III--Synthesis and CNS activity of some 1-substituted derivatives of the novel heterocyclic system 4,5-dihydro-s-triazolo [3,4-d]-1,5-benzothiazepine. Il Farmaco; edizione scientifica, 1987, Volume: 42, Issue:8 Topics: Animals; Anticonvulsants; Central Nervous System Depressants; Chemical Phenomena; Chemistry; Drug Interactions; Hexobarbital; Lethal Dose 50; Male; Mice; Motor Activity; Pentylenetetrazole; Sleep; Thiazepines; Thiazines; Tranquilizing Agents	1987
Pharmacology of ephedroxanes. Journal of ethnopharmacology, 1985, Volume: 13, Issue:2 Topics: Analgesics; Anesthesia; Animals; Anticonvulsants; Anura; Blepharoptosis; Blood Pressure; Body Temperature; Chickens; Drug Synergism; Electroshock; Guinea Pigs; Heart Rate; Hexobarbital; In Vitro Techniques; Male; Mice; Motor Activity; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Oxazoles; Pentylenetetrazole; Postural Balance; Rats; Rats, Inbred Strains; Strychnine	1985
[Change in the activity of a cell-free protein-synthesizing system with different functional states of the central nervous system]. Voprosy meditsinskoi khimii, 1972, Volume: 18, Issue:2 Topics: Anesthesia; Animals; Brain; Cell-Free System; Chlorpromazine; gamma-Aminobutyric Acid; Hexobarbital; In Vitro Techniques; Methionine; Microsomes; Nerve Tissue Proteins; Pentylenetetrazole; Rabbits; Seizures; Semicarbazides; Sulfur Radioisotopes; Thiopental	1972
The synthesis and pharmacology of a novel benzodiazepine derivative, 1-methyl-5-(o-fluorophenyl)-7-chloro-1,3-dihydro-2H-1,4-benzodiazepin-2-one(ID-540). Arzneimittel-Forschung, 1974, Volume: 24, Issue:10 Topics: Aggression; Animals; Anti-Anxiety Agents; Behavior, Animal; Bemegride; Benzodiazepinones; Cats; Chlorprothixene; Diazepam; Drug Synergism; Electroencephalography; Electroshock; Female; Fluorobenzenes; Hexobarbital; Humans; Lethal Dose 50; Male; Mice; Motor Activity; Muscle Tonus; Olfactory Bulb; Pentylenetetrazole; Rats; Reflex; Seizures; Septum Pellucidum; Strychnine	1974
Structure-activity relationships within the class of 1,4-benzodiazepines: presence of chlorine and central nervous system activities. Current therapeutic research, clinical and experimental, 1974, Volume: 16, Issue:4 Topics: Animals; Anticonvulsants; Benzodiazepinones; Chlorine; Drug Synergism; Female; Hexobarbital; Mice; Motor Activity; Muscle Relaxants, Central; Pentylenetetrazole; Sleep; Structure-Activity Relationship; Strychnine	1974
The site of action of the optical isomers of 1-methyl-5-phenyl-5-propyl barbituric acid. Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 282, Issue:4 Topics: Action Potentials; Animals; Barbiturates; Binding Sites; Blood Pressure; Cats; Decerebrate State; Electric Conductivity; Electric Stimulation; Hexobarbital; Isomerism; Membranes; Neurons; Pentylenetetrazole; Rats; Reflex; Reflex, Monosynaptic	1974
8-substituted theophyllines. In vitro inhibition of 3',5'-cyclic adenosine monophosphate phosphodiesterase and pharmacological spectrum in mice. Journal of medicinal chemistry, 1971, Volume: 14, Issue:12 Topics: Animals; Antidepressive Agents; Blood Glucose; Brain; Central Nervous System; Cyclic AMP; Dihydroxyphenylalanine; Diuresis; Drug Interactions; Drug Synergism; Hexobarbital; Injections, Intraperitoneal; Lethal Dose 50; Mice; Mice, Inbred Strains; Motor Activity; Pentylenetetrazole; Phosphoric Monoester Hydrolases; Structure-Activity Relationship; Theophylline; Time Factors	1971
Role of drug metabolism in drug research and development: factors affecting metabolism of drugs and their pharmacological and toxicological activity. Journal of pharmaceutical sciences, 1972, Volume: 61, Issue:10 Topics: Animals; Benzene Derivatives; Benzopyrenes; Cortisone; Cytochrome c Group; Cytochrome P-450 Enzyme System; Dealkylation; Diazepam; Female; Guinea Pigs; Hexobarbital; Hydroxylation; Male; Methylcholanthrene; Mice; Microsomes, Liver; Morphine; Oxidoreductases; Pentylenetetrazole; Pharmaceutical Preparations; Phenobarbital; Rats; Research; Sleep; Spironolactone	1972
Shortening of coma duration in narcotic poisoning. International anesthesiology clinics, 1966,Summer, Volume: 4, Issue:2 Topics: Central Nervous System Stimulants; Coma; Diuresis; Hexobarbital; Humans; Narcotics; Nikethamide; Pentylenetetrazole; Picrotoxin; Renal Dialysis	1966
Basic dihydromorphanthridinones with anticonvulsant activity. The Journal of pharmacy and pharmacology, 1969, Volume: 21, Issue:8 Topics: Animals; Anticonvulsants; Ataxia; Dibenzazepines; Electroshock; Ethanol; Female; Hexobarbital; Male; Mice; Pentylenetetrazole; Rats	1969
Absence of central nervous system effects of practalol [ICI 50,172; 4-(2-hydroxy-3-isopropylaminopropoxy)-acetanilide], a new adrenergic beta-receptor blocking drug. The Journal of pharmacy and pharmacology, 1969, Volume: 21, Issue:8 Topics: Acetanilides; Anesthetics; Animals; Central Nervous System; Hexobarbital; Male; Mice; Motor Activity; Pentylenetetrazole; Propranolol; Sympatholytics	1969
Pharmacology of a nicotinamido-methylaminopyrazolone (Ra 101). Arzneimittel-Forschung, 1970, Volume: 20, Issue:8 Topics: Aminopyrine; Amphetamine; Analgesics; Animals; Anti-Inflammatory Agents; Anticonvulsants; Carrageenan; Croton Oil; Depression, Chemical; Dextrans; Drug Synergism; Edema; Female; Fever; Glutethimide; Granuloma; Hexobarbital; Histamine H1 Antagonists; Hypnotics and Sedatives; Male; Mice; Motor Activity; Pentylenetetrazole; Phenylbutazone; Polysaccharides, Bacterial; Pyrazoles; Rabbits; Rats; Seizures	1970
Influence of alkylamides of glutamic acid and related compounds on the central nervous system. I. Central depressant effect of theanine. Chemical & pharmaceutical bulletin, 1971, Volume: 19, Issue:6 Topics: Amides; Amino Acids; Animals; Bemegride; Brain; Brain Chemistry; Caffeine; Carbon Isotopes; Central Nervous System; Depression, Chemical; Glutamine; Hexobarbital; Liver; Male; Mice; Pentylenetetrazole; Picrotoxin; Piperidines; Seizures; Sleep; Strychnine	1971
Investigation on pharmacological properties of hexadiphane, oxazepam hemisuccinate and of their combination. Current therapeutic research, clinical and experimental, 1972, Volume: 14, Issue:6 Topics: Animals; Azepines; Benzene Derivatives; Diphenylacetic Acids; Drug Synergism; Female; Gallbladder; Guinea Pigs; Hexobarbital; In Vitro Techniques; Male; Methamphetamine; Mice; Motor Activity; Muscle Contraction; Muscle, Smooth; Oxazepam; Papaverine; Parasympatholytics; Pentylenetetrazole; Peptic Ulcer; Rats; Seizures; Sleep	1972
Analeptic effects of N-sulfamoyl-hexahydro-azepine, SaH 41-178. Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 200, Issue:2 Topics: Analgesics; Animals; Azepines; Cardiovascular System; Cats; Central Nervous System; Central Nervous System Stimulants; Doxapram; Electrodes, Implanted; Electroencephalography; Hexobarbital; Male; Mice; Pentobarbital; Pentylenetetrazole; Respiratory System; Sleep; Sulfonamides	1972
Comparative evaluation of the central nervous system activity of diazepam and its metabolites (demethyl-diazepam, methyl-oxazepam and oxazepam). Pharmacological research communications, 1974, Volume: 6, Issue:1 Topics: Animals; Central Nervous System; Dealkylation; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Female; Hexobarbital; Hydroxylation; Mice; Motor Activity; Muscle Relaxants, Central; Muscles; Oxazepam; Pentylenetetrazole; Sleep; Strychnine; Time Factors	1974
[Effects of picrotoxin and pentetrazol on experimental sleep in the mouse]. Archives des sciences physiologiques, 1974, Volume: 28, Issue:3 Topics: Animals; Brain Chemistry; Chloral Hydrate; Chlormethiazole; Hexobarbital; Pentobarbital; Pentylenetetrazole; Picrotoxin; Sleep; Time Factors	1974
Central effects of a series of N1-, N4-acyl piperazine derivatives. Acta physiologica et pharmacologica Bulgarica, 1974, Volume: 1 Topics: Animals; Behavior, Animal; Cerebral Cortex; Evoked Potentials; Female; Hexobarbital; Humans; Lethal Dose 50; Male; Mice; Motor Activity; Pentylenetetrazole; Piperazines; Rabbits; Rage; Rats; Reserpine; Seizures; Stereotyped Behavior; Strychnine	1974
Stereostructure-activity relationships for oxazepam hemisuccinate. Effects on central nervous system. Arzneimittel-Forschung, 1972, Volume: 22, Issue:8 Topics: Animals; Anticonvulsants; Central Nervous System; Drug Synergism; Female; Hexobarbital; Isomerism; Mice; Motor Activity; Muscle Relaxants, Central; Oxazepam; Pentylenetetrazole; Sleep; Structure-Activity Relationship; Strychnine; Succinates; Tranquilizing Agents	1972
Synthesis and CNS activity of 3-substituted 7-chloro-5-phenyl-1,3,4-benzotriazepin-2-ones. Journal of pharmaceutical sciences, 1974, Volume: 63, Issue:6 Topics: Alkylation; Animals; Anticonvulsants; Behavior, Animal; Benzazepines; Central Nervous System; Chlordiazepoxide; Cricetinae; Cyclization; Depression, Chemical; Diazepam; Drug Synergism; Electroshock; Exploratory Behavior; Hexobarbital; Hypnotics and Sedatives; Lethal Dose 50; Mass Spectrometry; Methamphetamine; Mice; Motor Activity; Muscle Tonus; Pentylenetetrazole; Reflex; Sleep	1974
Pharmacological studies on 2-methyl-3(2'-methyl-4'-chlorophenyl)-5-chloro-4[H)-quinazolinone (SL-164). Arzneimittel-Forschung, 1969, Volume: 19, Issue:12 Topics: Aggression; Analgesics; Animals; Anticonvulsants; Avoidance Learning; Behavior, Animal; Blood Pressure; Cats; Chlordiazepoxide; Chlorpromazine; Drug Synergism; Electroencephalography; Haplorhini; Heart; Hexobarbital; Humans; Hypnotics and Sedatives; In Vitro Techniques; Male; Meprobamate; Methaqualone; Mice; Morphine; Muscle Relaxants, Central; Muscle, Smooth; Pentylenetetrazole; Quinazolines; Rabbits; Rats; Respiration; Strychnine; Tranquilizing Agents	1969
Neuropharmacological profile of 1-azaphenothiazine-10-thiolcarboxylates. Journal of medicinal chemistry, 1971, Volume: 14, Issue:10 Topics: Adrenal Glands; Animals; Antihypertensive Agents; Ataxia; Cats; Depression, Chemical; Dogs; Drug Interactions; Haplorhini; Hexobarbital; Lethal Dose 50; Male; Mice; Mice, Inbred Strains; Motor Activity; Norepinephrine; Pentylenetetrazole; Phenothiazines; Rats; Respiration; Touch; Vocalization, Animal	1971
2,5-dihydro-1,2,4-benzothiadiazepine 1,1-dioxides. Synthesis and pharmacological evaluation. Journal of medicinal chemistry, 1972, Volume: 15, Issue:9 Topics: Animals; Behavior, Animal; Benzazepines; Cyclic S-Oxides; Hexobarbital; Infrared Rays; Male; Mice; Motor Activity; Pentylenetetrazole; Sleep; Spectrum Analysis; Strychnine; Sulfoxides	1972
[Pharmacological studies of a new minor tranquilizer, dipotassium chlorazepate (7-chloro-1,3-dihydro-2-oxo-5-phenyl-1H-1, 4-benzodiazepine 3-carboxylic acid monopotassium salt monopotassium hydroxide). 1. Central action]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1972, Volume: 68, Issue:3 Topics: Animals; Anticonvulsants; Apomorphine; Bemegride; Benzazepines; Central Nervous System; Cerebral Cortex; Diazepam; Dogs; Electroencephalography; Evoked Potentials; Hexobarbital; Hypothalamus; Limbic System; Male; Mice; Morphine; Nicotine; Pentylenetetrazole; Rats; Strychnine; Tranquilizing Agents; Tremorine	1972
Pharmacologic evaluation of 3,4-dimethoxyphenylpropenes and 3,4-dimethoxyphenylpropanediols. Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 199, Issue:2 Topics: Animals; Avoidance Learning; Behavior, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Eugenol; Glycols; Hexobarbital; Injections, Intraperitoneal; Lethal Dose 50; Male; Methylation; Mice; Mice, Inbred Strains; Motor Activity; Pentylenetetrazole; Seizures; Structure-Activity Relationship; Strychnine	1972
The effects of 3- -dimethylaminopropyl-3-phenylphthalide (I.C.I. 53,165) on brain monoamines and their precursors. Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 199, Issue:1 Topics: Animals; Anticonvulsants; Benzene Derivatives; Benzofurans; Biogenic Amines; Body Temperature; Brain; Dextroamphetamine; Dimethylamines; Electroshock; Hexobarbital; Ketones; Lethal Dose 50; Methyltyrosines; Mice; Norepinephrine; Oxotremorine; Pentylenetetrazole; Rats; Reserpine; Salivation; Serotonin; Sleep; Tyramine	1972
Terpene compounds as drugs. 14. Terpenyl carbamates as central nervous system depressants. Journal of medicinal chemistry, 1972, Volume: 15, Issue:9 Topics: Animals; Anticonvulsants; Behavior, Animal; Carbamates; Central Nervous System; Depression, Chemical; Electroshock; Hexobarbital; Lethal Dose 50; Motor Activity; Pentylenetetrazole; Sleep; Terpenes	1972
[Pharmacological studies of troponoids. I. Hypothermic, analgesic and anti-inflammatory actions of troponoids]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1971, Volume: 91, Issue:5 Topics: Aminopyrine; Analgesics; Animals; Anti-Inflammatory Agents; Antipyrine; Aspirin; Body Temperature; Capillary Permeability; Chlorpromazine; Cycloheptanes; Erythema; Hexobarbital; Ketones; Male; Mice; Motor Activity; Pentylenetetrazole; Rats; Salicylates; Sleep; Strychnine	1971
[Effects of Natulan (procarbazine hydrochloride) on the central nervous system]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1971, Volume: 67, Issue:3 Topics: Analgesics; Animals; Behavior, Animal; Benzoates; Catalepsy; Central Nervous System; Chlorpromazine; Depression, Chemical; Electric Stimulation; Electroencephalography; Hexobarbital; Humans; Male; Mice; Morphine; Movement; Muscle Relaxants, Central; Pentylenetetrazole; Procarbazine; Rabbits; Rats; Reserpine; Sleep; Spasm	1971
Neuromuscular functions of mature mice following neonatal monosodium glutamate. Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 189, Issue:1 Topics: Animals; Animals, Newborn; Body Weight; Crowding; Dextroamphetamine; Female; Food Additives; Glutamates; Gonads; Heart; Hexobarbital; Kidney; Liver; Lung; Male; Mice; Motor Activity; Movement; Muscles; Nervous System; Nervous System Diseases; Organ Size; Paralysis; Pentylenetetrazole; Physical Exertion; Pressure; Sleep; Spleen; Swimming; Time Factors; Zoxazolamine	1971
The effect of mescaline and bufotenine on some central actions of noradrenaline. Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 194, Issue:1 Topics: Amobarbital; Animals; Body Temperature; Central Nervous System; Depression, Chemical; Drug Antagonism; Drug Synergism; Female; Hallucinations; Hallucinogens; Hexobarbital; Humans; Hypothermia; Mescaline; Mice; Norepinephrine; Pentylenetetrazole; Receptors, Adrenergic	1971
Chemistry and CNS-pharmacological properties of two hydrosoluble benzodiazepine derivatives. Arzneimittel-Forschung, 1969, Volume: 19, Issue:12 Topics: Animals; Avoidance Learning; Behavior, Animal; Central Nervous System; Chemical Phenomena; Chemistry, Physical; Depression, Chemical; Diazepam; Dibenzazepines; Drug Synergism; Hexobarbital; Locomotion; Male; Methamphetamine; Motor Activity; Oxazepam; Pentylenetetrazole; Rats; Stimulation, Chemical; Time Factors	1969
Discharge patterns of single reticular neuron synchronized with electrocortical spike induced by pentetrazol. The Tohoku journal of experimental medicine, 1970, Volume: 100, Issue:1 Topics: Animals; Electroencephalography; Female; Hexobarbital; Injections, Intravenous; Lidocaine; Male; Neurons; Pentylenetetrazole; Phenytoin; Rats; Reticular Formation	1970
[Comparison of the characteristics of the effect of tranquilizing agents under experimental and clinical conditions]. Farmakologiia i toksikologiia, 1971, Volume: 34, Issue:1 Topics: Animals; Anticonvulsants; Behavior, Animal; Central Nervous System Diseases; Chlordiazepoxide; Depression, Chemical; Diazepam; Drug Synergism; Electroshock; Emotions; Hexobarbital; Humans; Hypnotics and Sedatives; Mental Disorders; Meprobamate; Mice; Morpholines; Movement; Muscle Relaxants, Central; Neurotic Disorders; Orientation; Oxazepam; Pentylenetetrazole; Rats; Schizophrenia; Strychnine; Tranquilizing Agents	1971
Substitution in the hydantoin ring. VII. N-3-Propionic acid and its ethyl ester and N-3-(2-cyanoethyl) derivatives. Journal of medicinal chemistry, 1968, Volume: 11, Issue:3 Topics: Alkylation; Animals; Drug Synergism; Electroshock; Hexobarbital; Hydantoins; Infrared Rays; Magnetic Resonance Spectroscopy; Male; Mice; Motor Activity; Pentylenetetrazole; Phenytoin; Propionates; Spectrum Analysis; Ultraviolet Rays	1968
The hypnotic properties of 8-ethylthio-6-thiotheophylline sodium. Toxicology and applied pharmacology, 1968, Volume: 12, Issue:2 Topics: Amphetamine; Animals; Caffeine; Chloral Hydrate; Chlorpromazine; Dogs; Drug Synergism; Hexobarbital; Hypnotics and Sedatives; Male; Meprobamate; Methylphenidate; Mice; Morphine; Nalorphine; Nikethamide; Pentobarbital; Pentylenetetrazole; Phenobarbital; Rabbits; Rats; Reserpine; Sleep; Theophylline; Thiopental	1968
Comparative effects of chlorpromazine hydrochloride and quaternary chlorpromazine hydrochloride on the central nervous systems of rats and mice. Journal of pharmaceutical sciences, 1968, Volume: 57, Issue:12 Topics: Animals; Avoidance Learning; Behavior, Animal; Carbon Isotopes; Chlorpromazine; Drug Synergism; Electroshock; Hexobarbital; Male; Mice; Motor Activity; Pentylenetetrazole; Quaternary Ammonium Compounds; Rats; Sleep; Strychnine	1968
Alteration of the flicker fusion frequency and auditory thresholds in man by Frenolon and Trioxazine compared with other centrally acting compounds. Therapia Hungarica (English edition), 1968, Volume: 16, Issue:3 Topics: Auditory Threshold; Caffeine; Dioxoles; Flicker Fusion; Hexobarbital; Humans; Meprobamate; Methods; Morpholines; Pentylenetetrazole; Tranquilizing Agents	1968
On the central action of some oxoindole compounds. Archivum immunologiae et therapiae experimentalis, 1969, Volume: 17, Issue:1 Topics: Absorption; Amphetamine; Animals; Blood Pressure; Central Nervous System; Depression; Drug Antagonism; Drug Synergism; Ethyl Ethers; Hexobarbital; Humans; Hyperkinesis; Indoles; Injections, Intraperitoneal; Mice; Pentylenetetrazole; Rabbits; Seizures; Serotonin; Strychnine	1969
[Modification of central mechanisms of action by anticholinergics]. Arzneimittel-Forschung, 1969, Volume: 19, Issue:1 Topics: Aggression; Amphetamine; Animals; Apomorphine; Atropine; Biperiden; Bridged-Ring Compounds; Central Nervous System; Chlorpromazine; Depression, Chemical; Drug Synergism; Esters; Female; Hexobarbital; Humans; Imipramine; Male; Mice; Morphine; Nicotine; Parasympatholytics; Pentylenetetrazole; Perphenazine; Rats; Stimulation, Chemical; Strychnine; Tremorine	1969
Some central effects of SQ 10,643 [2'3-(-dimethlaminopropylthio) cinnamanilide hydrochloride], a potent serotonin antagonist. Archives internationales de pharmacodynamie et de therapie, 1965, Volume: 155, Issue:1 Topics: Animals; Avoidance Learning; Behavior, Animal; Body Temperature; Cats; Electroconvulsive Therapy; Electroencephalography; Hexobarbital; Iproniazid; Mice; Pentylenetetrazole; Rats; Reserpine; Seizures; Self Stimulation; Serotonin	1965
Influence on central nervous system of 39p-propionyl-o-methoxy-phenoxy)-1,2-propanediol. Experientia, 1964, Aug-15, Volume: 20, Issue:8 Topics: Amphetamine; Animals; Anticonvulsants; Behavior, Animal; Caffeine; Central Nervous System; Cocaine; Hexobarbital; Mephenesin; Pentylenetetrazole; Propylene Glycols; Rabbits; Rats; Strychnine	1964
Studies on the central action of new derivatives of barbituric acid. Archivum immunologiae et therapiae experimentalis, 1966, Volume: 14, Issue:5 Topics: Animals; Barbiturates; Chloral Hydrate; Drug Antagonism; Drug Synergism; Hexobarbital; Mice; Movement; Pentylenetetrazole; Strychnine	1966
The anticonvulsant activity of 4-alpha,8-alpha-naphthalenedicarboximide and its derivatives. Journal of medicinal chemistry, 1967, Volume: 10, Issue:4 Topics: Animals; Behavior, Animal; Chemistry, Organic; Electric Stimulation; Electrophysiology; Electroshock; Hexobarbital; Imides; Male; Mice; Naphthalenes; Organic Chemistry Phenomena; Pentylenetetrazole; Seizures; Sleep; Strychnine	1967
Thyroliberin (thyrotropin releasing hormone): antagonism of halothane and hexobarbital narcosis in mice. Comparison with pentetrazol, caffeine, d-amphetamine and adrenaline. Arzneimittel-Forschung, 1982, Volume: 32, Issue:3 Topics: Animals; Caffeine; Dextroamphetamine; Dose-Response Relationship, Drug; Epinephrine; Halothane; Hexobarbital; Male; Mice; Mice, Inbred Strains; Pentylenetetrazole; Thyrotropin-Releasing Hormone	1982
[Preliminary pharmacological studies on 6 new derivatives of 5-phenylimidazoline]. Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina, 1981, Volume: 36 Topics: Animals; Convulsants; Drug Synergism; Hexobarbital; Hypnotics and Sedatives; Imidazoles; Mice; Mice, Inbred Strains; Motor Activity; Pentylenetetrazole; Seizures; Serotonin Antagonists; Sleep	1981
[Anticonvulsant effects of indoline derivatives]. Die Pharmazie, 1982, Volume: 37, Issue:12 Topics: Animals; Anticonvulsants; Electroshock; Hexobarbital; Indoles; Mice; Pentylenetetrazole	1982
[Effect of new pyrazolo-(1,2-a)-1,2,5-triazepine derivatives on the central nervous system]. Acta poloniae pharmaceutica, 1982, Volume: 39, Issue:5-6 Topics: Animals; Anticonvulsants; Azepines; Drug Synergism; Hexobarbital; Hypnotics and Sedatives; Mice; Mice, Inbred BALB C; Motor Activity; Pentylenetetrazole; Pyrazoles; Rats; Rats, Inbred Strains; Seizures	1982
[Pharmacological characterization of novel pyridazines. Part 1: Physicochemical parameters, acute toxicity and action on the central nervous system (author's transl)]. Die Pharmazie, 1981, Volume: 36, Issue:10 Topics: Animals; Central Nervous System; Chemical Phenomena; Chemistry, Physical; Diazepam; Drug Interactions; Hexobarbital; Lethal Dose 50; Mice; Motor Activity; Pentylenetetrazole; Pyridazines	1981
General pharmacology of the putative cognition enhancer linopirdine. Arzneimittel-Forschung, 1995, Volume: 45, Issue:4 Topics: Animals; Behavior, Animal; Body Temperature; Catalepsy; Cognition; Convulsants; Hexobarbital; Indoles; Male; Mice; Mice, Inbred Strains; Pain Measurement; Pentylenetetrazole; Postural Balance; Pyridines; Rats; Rats, Wistar	1995
Central action of some cytostatics--methotrexate (MTX) and doxorubicin (DXR). II. The influence on the seizure activity and the learning and memory processes in mice. Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina, 1998, Volume: 53 Topics: Animals; Brain; Doxorubicin; Drug Interactions; Female; gamma-Aminobutyric Acid; Hexobarbital; Learning; Male; Memory; Methotrexate; Mice; Pentylenetetrazole; Seizures; Sleep	1998
Synthesis and pharmacological activity of new carbonyl derivatives of 1-aryl-2-iminoimidazolidine: part 2. Synthesis and pharmacological activity of 1,6-diaryl-5,7(1H)dioxo-2,3-dihydroimidazo[1,2-a][1,3,5]triazines. European journal of medicinal chemistry, 2002, Volume: 37, Issue:9 Topics: 5-Hydroxytryptophan; Analgesics, Opioid; Animals; Behavior, Animal; Binding, Competitive; Body Temperature; Convulsants; Crystallography, X-Ray; Hexobarbital; Hypnotics and Sedatives; Indicators and Reagents; Magnetic Resonance Spectroscopy; Male; Mice; Models, Molecular; Motor Activity; Pain Measurement; Pentylenetetrazole; Reaction Time; Receptor, Serotonin, 5-HT2A; Receptors, GABA-A; Receptors, Opioid, mu; Receptors, Serotonin; Seizures; Sleep; Stereotyped Behavior; Triazines	2002
[Role of the vegetative nervous system in combined application of cardiazole and evipan]. Magyar belorvosi archivum, 1950, Volume: 3, Issue:4 Topics: Autonomic Nervous System; Barbiturates; Hexobarbital; Humans; Pentylenetetrazole	1950
[Effect of narcotics, analeptics, secale preparations and phenothiazine derivatives on the vagal respiratory and circulatory reflexes in the rat and guinea pig]. Medicina experimentalis : International journal of experimental medicine, 1962, Volume: 7 Topics: Animals; Bemegride; Blood Circulation; Central Nervous System Stimulants; Chloralose; Chlorpromazine; Ergot Alkaloids; Guinea Pigs; Hexobarbital; Morphine; Narcotics; Pentobarbital; Pentylenetetrazole; Promazine; Promethazine; Rats; Reflex; Respiration; Secale; Thiopental; Vagus Nerve	1962
BEHAVIOURAL AND PHARMACOLOGICAL STUDIES OF A TRANQUILISING FRACTION FROM THE OIL OF CELASTRUS PANICULATUS (MALKANGUNI OIL). Archives internationales de pharmacodynamie et de therapie, 1963, Jul-01, Volume: 144 Topics: Amphetamine; Amphetamines; Animals; Anticonvulsants; Behavior, Animal; Blood Pressure; Blood Pressure Determination; Body Temperature; Cats; Celastrus; Diuresis; Dogs; Haplorhini; Hexobarbital; Hypnotics and Sedatives; Mice; Morphine; Nervous System; Oils; Pentylenetetrazole; Pharmacology; Plants, Medicinal; Research; Reserpine; Toxicology; Tranquilizing Agents	1963
[TOLERANCE OF SMALL LABORATORY ANIMALS TO INTRAVENOUS INJECTION OF QUANTITIES OF FLUIDS AND THE INFLUENCE OF THE VOLUME OF THE INJECTION ON SOME DRUG EFFECTS]. Medicina experimentalis : International journal of experimental medicine, 1963, Volume: 9 Topics: Animals; Animals, Laboratory; Drug Tolerance; Hexobarbital; Injections; Injections, Intravenous; Isotonic Solutions; Mice; Pentylenetetrazole; Pharmaceutical Vehicles; Pharmacology; Rats; Research; Sodium Chloride; Toxicology; Water	1963
[EFFECT OF STIMULANTS AND DEPRESSANTS ON THE ACTIVITY OF SINGLE NEURONS OF THE SPINAL CORD FOLLOWING CEREBELLAR STIMULATION]. Biulleten' eksperimental'noi biologii i meditsiny, 1964, Volume: 57 Topics: Brain; Caffeine; Cats; Cerebellum; Electric Stimulation; Electrophysiology; Hexobarbital; Neurons; Pentobarbital; Pentylenetetrazole; Pharmacology; Piperidines; Research; Spinal Cord; Spinal Nerves; Urethane	1964
INVESTIGATION OF 3-(10,11-DIHYDRO-5H-DIBENZO (A,D) CYCLOHEPTEN-5-YLOXY) TROPANE CITRATE (DIBENZHEPTROPINE CITRATE, BRONTINE). I. PHARMACOLOGICAL PROPERTIES. II. TOXICOLOGICAL PROPERTIES. Archives internationales de pharmacodynamie et de therapie, 1964, Mar-01, Volume: 148 Topics: Acetylcholine; Albumins; Animals; Asthma; Atropine; Bronchi; Citric Acid; Cyproheptadine; Diphenhydramine; Dogs; Edema; Fever; Gastric Juice; Guinea Pigs; Heterocyclic Compounds; Hexobarbital; Histamine H1 Antagonists; Morphine; Muscle Relaxants, Central; Parasympatholytics; Pentylenetetrazole; Pharmacology; Pupil; Quaternary Ammonium Compounds; Rabbits; Rats; Research; Salivation; Serotonin; Toxicology; Tranquilizing Agents; Tropanes	1964
INFLUENCE OF METHYLDOPA ON CENTRAL EFFECTS OF RESERPINE. British journal of pharmacology and chemotherapy, 1964, Volume: 22 Topics: Anesthesia; Animals; Birds; Brain; Brain Chemistry; Chlorpromazine; Hexobarbital; Hypnotics and Sedatives; Methyldopa; Mice; Pentylenetetrazole; Pharmacology; Research; Reserpine; Seizures; Serotonin; Vomiting	1964
[THE CENTRAL STIMULATING ACTION OF DIETHYLPROPION IN COMPARISON WITH PHENMETRAZINE AND RACEMIC BENZEDRINE]. Archives internationales de pharmacodynamie et de therapie, 1964, Jun-01, Volume: 149 Topics: Amphetamine; Amphetamines; Behavior, Animal; Blood Pressure; Body Temperature Regulation; Central Nervous System; Central Nervous System Stimulants; Diethylpropion; Dogs; Ether; Hexobarbital; Mice; Pentylenetetrazole; Pharmacology; Phenmetrazine; Rabbits; Research; Reserpine; Seizures; Toxicology	1964
[ANTICONVULSIVE EFFECTS OF OXINDOL AND DIOXINDOL]. Medicina experimentalis : International journal of experimental medicine, 1964, Volume: 11 Topics: Anesthesia; Anesthesiology; Anticonvulsants; Azoles; Electroshock; Hexobarbital; Imides; Indoles; Mice; Pentylenetetrazole; Pharmacology; Phthalic Acids; Research; Seizures; Toxicology	1964
THE PLACE OF ACETYLSALICYLIC ACID IN PSYCHOPHARMACOLOGY. AN EXPERIMENTAL STUDY. Arzneimittel-Forschung, 1963, Volume: 13 Topics: Amphetamine; Amphetamines; Animals; Aspirin; Body Temperature Regulation; Chlordiazepoxide; Chlorpromazine; Electrophysiology; Ether; Guinea Pigs; Hexobarbital; Meprobamate; Mice; Morphine; Nikethamide; Pain; Pentylenetetrazole; Pharmacology; Phenobarbital; Poisoning; Psychopharmacology; Rabbits; Research; Sensory Receptor Cells; Sleep; Strychnine; Thiopental	1963
STRUCTURE-ACTIVITY RELATIONSHIP IN THE PHENYLISOPROPYLAMINE GROUP. V. THE ACTION OF DL-M AND P-DI-(2-AMINOPROPYL)-BENZENES ON THE CENTRAL NERVOUS SYSTEM. Archivum immunologiae et therapiae experimentalis, 1964, Volume: 12 Topics: Amphetamine; Amphetamines; Anesthesia; Animals; Benzene; Central Nervous System; Chemistry, Pharmaceutical; Chloral Hydrate; Drug Synergism; Ether; Hexobarbital; Hypnotics and Sedatives; Mice; Movement; Pentylenetetrazole; Pharmacology; Research; Structure-Activity Relationship	1964
[PHARMACOLOGIC STUDY OF RETURN TO SLEEP INDUCED IN THE RAT BY SUDDEN CHANGE IN ENVIRONMENTAL TEMPERATURE]. Medicina et pharmacologia experimentalis. International journal of experimental medicine, 1965, Volume: 13 Topics: Adrenalectomy; Amphetamine; Amphetamines; Caffeine; Chloral Hydrate; Cocaine; Dihydroergotoxine; Ergot Alkaloids; Hexobarbital; Hypnotics and Sedatives; Iproniazid; Pentobarbital; Pentylenetetrazole; Pharmacology; Pregnanediones; Rats; Research; Reserpine; Sleep; Temperature; Yohimbine	1965
General pharmacology of KP-102 (GHRP-2), a potent growth hormone-releasing peptide. Arzneimittel-Forschung, 2004, Volume: 54, Issue:12 Topics: Acetic Acid; Analgesics; Animals; Anticonvulsants; Behavior, Animal; Blood Coagulation; Body Temperature; Convulsants; Dogs; Electroencephalography; Electroshock; Female; Gastrointestinal Motility; Gastrointestinal Transit; Growth Hormone-Releasing Hormone; Guinea Pigs; Hemodynamics; Hexobarbital; Hypnotics and Sedatives; Kidney; Male; Mice; Mice, Inbred ICR; Motor Activity; Muscle Contraction; Muscle, Skeletal; Muscle, Smooth; Muscle, Smooth, Vascular; Oligopeptides; Pain Measurement; Pentylenetetrazole; Postural Balance; Rabbits; Rats; Rats, Sprague-Dawley; Reflex; Respiratory Mechanics; Sleep; Uterine Contraction	2004
Effects of Hypericum montbretti extract on the central nervous system and involvement of GABA (A)/Benzodiazepine receptors in its pharmacological activity. Phytotherapy research : PTR, 2012, Volume: 26, Issue:11 Topics: Animals; Anticonvulsants; Behavior, Animal; Central Nervous System; Diazepam; Exploratory Behavior; Hexobarbital; Hypericum; Hypnotics and Sedatives; Male; Mice; Motor Activity; Pentylenetetrazole; Plant Extracts; Receptors, GABA-A; Seizures; Sleep	2012