pentylenetetrazole has been researched along with glutamic acid in 90 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (5.56) | 18.7374 |
| 1990's | 23 (25.56) | 18.2507 |
| 2000's | 31 (34.44) | 29.6817 |
| 2010's | 27 (30.00) | 24.3611 |
| 2020's | 4 (4.44) | 2.80 |
| Authors | Studies |
|---|---|
| Garyaev, AP; Piotrovsky, LB; Poznyakova, LN | 1 |
| Kent, AP; Webster, RA | 1 |
| Hutchison, AJ; Lehmann, J; McPherson, SE; Mondadori, C; Murphy, DE; Schmutz, M; Sinton, CM; Steel, DJ; Tsai, C; Williams, M | 1 |
| Mark, RF; Sanberg, PR | 1 |
| Cates, LA; Coyle, JT; Ferkany, JW; Hu, ZS; Lehmann, J; Li, VS | 1 |
| Arbabha, B; Bansinath, M; Garg, UC; Turndorf, H | 1 |
| Campos Júnior, RR; Freire, E; Guertzenstein, PG; Russo, AK; Silva, AC; Tolentino-Silva, FP | 1 |
| Bolster, B; Dakshinamurti, K; Sharma, SK | 1 |
| Krug, M; Schlichthaar, R; Schröder, H | 1 |
| Becker, A; Lössner, B; Schröder, H | 1 |
| Becker, A; Grecksch, G; Schröder, H | 1 |
| Kusá, R; Mares, P; Roztocilová, L; Velísek, L | 1 |
| Ito, M; Kishi, K; Sejima, H; Shiraishi, H; Tsuda, H | 1 |
| Janzen, J; Peghini, P; Stoffel, W | 1 |
| Becker, A; Krug, M; Schröder, H | 1 |
| Dunworth, SJ; Stephens, DN | 1 |
| da Silva, LF; Elisabetsky, E; Pereira, P | 1 |
| Becker, A; Hoellt, V; Schroeder, H | 1 |
| Nakanishi, H; Tominaga, K; Yamamoto, K; Yasuda, Y | 1 |
| Berdiev, RK; Chepurnov, SA; Chepurnova, NE | 1 |
| Becker, A; Hoellt, V; Schröeder, H; Schröeder, U | 1 |
| Becker, A; Braun, H; Grecksch, G; Höllt, V; Schröder, H | 1 |
| Bot, AP; Corner, MA | 1 |
| Brum, LF; Elisabetsky, E; Souza, DO | 1 |
| Becker, A; Grecksch, G; Höllt, V; Schroeder, H | 1 |
| Li, X; Xiao, Y | 1 |
| Choe, BK; Kim, SK; Kwon, GY; Shin, SW | 1 |
| Angelatou, F; Ekonomou, A | 1 |
| Abogadie, FC; Armstrong, H; Cruz, LJ; Donevan, SD; Hollmann, M; McCabe, RT; Olivera, BM; Paarmann, I; Rivier, JE; Torres, J; White, HS | 1 |
| Li, Z; Morimoto, T; Okada, S; Ono, J; Yamamoto, Y; Yamatodani, A | 1 |
| Arikan, K; Coskun, T; Guvener, B; Oran, O | 1 |
| Gutiérrez, R | 1 |
| Elisabetsky, E; Silva Brum, LF | 1 |
| Eloqayli, H; Hadidi, H; Qu, H; Sletvold, O; Sonnewald, U; Unsgård, G | 1 |
| Caldarone, BJ; Cremona, O; Daniell, L; De Camilli, P; Di Paolo, G; Flavell, R; Perucco, E; Picciotto, MR; Ryan, TA; Sankaranarayanan, S; Wenk, MR | 1 |
| Dahl, CB; Eloqayli, H; Götestam, KG; Hadidi, H; Sonnewald, U; Unsgård, G | 1 |
| Goncharenko, NV; Pankrat'ev, DV; Talalaenko, AN | 1 |
| Amat, G; Armijo, JA; Cuadrado, A | 1 |
| Alhonen, L; Gröhn, OH; Jänne, J; Kaasinen, SK; Keinänen, TA | 1 |
| Evseev, VA; Karpova, MN; Klishina, NY; Kuznetsova, LV; Trekova, NA; Vetrile, LA | 2 |
| Ayala Guerrero, F; Barragán Mejía, G; Calderón Guzmán, D; Espitia Vázquez, I; Juárez Olguín, H; Labra Ruiz, N; Rodríguez Pérez, R; Santamaria del Angel, D | 1 |
| Becker, A; Grecksch, G; Höllt, V; Kraus, J; Loh, H; Schroeder, H | 1 |
| Ha, JH; Koo, BS; Lee, DU; Lee, SI | 1 |
| Binder, DK; Haggie, PM; Papadopoulos, MC; Verkman, AS | 1 |
| Armijo, JA; Cuadrado, A | 1 |
| Bonavita, CD; Cereseto, M; Ferrero, AJ; Reinés, A; Rubio, MC; Sifonios, LL; Wikinski, SI | 1 |
| Bhardwaj, A; Keyl, PM; Mirski, MA; Sherman, DL; Zhang, N; Ziai, WC | 1 |
| Feng, Y; LeBlanc, MH; Regunathan, S | 1 |
| Bao, Y; Li, CZ; Xie, W; Yu, LJ | 1 |
| Karpova, MN; Klishina, NY; Kuznetsova, LV; Trekova, NA; Vetrile, LA | 1 |
| Bauer, L; Bertaso, F; Betz, H; Bockaert, J; Eulenburg, V; Fagni, L; Herin, GA; Lerner-Natoli, M; Scheschonka, A; Zhang, CS | 1 |
| Alonso-Cortes, D; del Carmen Gutiérrez, M; Estrada-Soto, S; Herrera-Ruiz, M; León-Rivera, I; Mirón-López, G; Molina-Salinas, GM; Navarrete-Vázquez, G; Ríos, MY; Said-Fernández, S | 1 |
| Fukuma, G; Hase, K; Hirose, S; Kaneko, S; Kijima, H; Kishi, A; Kojima, T; Mitsudome, A; Miura, Y; Mori, F; Ohno, H; Okada, M; Saito, R; Sato, A; Takahara, T; Takano, Y; Tomiyama, M; Ueno, S; Wakabayashi, K; Yoshida, S; Zhu, G | 1 |
| Dalla Corte, CL; Dalla Corte, LC; de Avila, DS; de Mello, CF; Fighera, MR; Furian, AF; Lima, FD; Oliveira, MS; Puntel, GO; Rambo, LM; Retamoso, LT; Ribeiro, LR; Royes, LF; Silva, LF; Soares, FA; Souza, MA | 1 |
| Doi, T; Nagatomo, K; Ueda, Y; Willmore, LJ | 1 |
| Bidziński, A; Hamed, A; Lehner, M; Maciejak, P; Płaźnik, A; Skórzewska, A; Sobolewska, A; Szyndler, J; Taracha, E; Turzyńska, D; Wisłowska-Stanek, A | 1 |
| Becker, L; Carmona, MA; Feddersen, B; Filosa, A; Gaitanos, L; Honsek, SD; Klein, R; Klopstock, T; Kullander, K; Paixão, S; Pasquale, EB; Rose, CR; Rudhard, Y; Schoepfer, R | 1 |
| Cao, W; Glushakov, AV; Martynyuk, AE; Mecca, AP; Seubert, CN; Shah, HP; Shi, P; Sumners, C | 1 |
| Xie, W; Yu, Y; Zhao, Y | 1 |
| Doi, T; Takaki, M; Ueda, Y; Willmore, LJ | 1 |
| Desai, PV; Therisa, KK | 1 |
| Chen, Z; Fan, YY; Fang, Q; He, P; Hu, WW; Ohtsu, H; Xu, TL; Xu, ZH; Yan, HJ; Yang, Y; Zhang, CY; Zhang, XN; Zhong, K | 1 |
| Fujita, Y; Harai, T; Hashimoto, K; Hongou, K; Horio, M; Inoue, R; Miyawaki, T; Mori, H; Tanaka, A | 1 |
| Dai, K; Hoshikawa, M; Niwa, O; Okada, M; Saito, H; Suzuki, N; Yamamura, S | 1 |
| Deng, Y; He, N; Ma, C; Wang, M; Wang, W | 1 |
| Loyens, E; Massie, A; Michotte, Y; Schallier, A; Smolders, I; Van Liefferinge, J; Vermoesen, K | 1 |
| Xie, W; Yu, YH; Zhao, YY | 1 |
| Karpova, MN; Klishina, NJ; Kuznetsova, LV; Vetrile, LA | 1 |
| Jiang, Y; Xiang, J | 1 |
| Curti, C; Delgado-Hernández, R; González-Durruthy, M; Marin-Prida, J; Nuñez-Figueredo, Y; Ochoa-Rodríguez, E; Pardo-Andreu, GL; Porto-Verdecia, M; Ramírez-Sánchez, J; Rodrigues, FP; Souza, DO; Uyemura, SA; Verdecia-Reyes, Y | 1 |
| Elahdadi Salmani, M; Goudarzi, E; Goudarzi, I; Lashkarbolouki, T | 1 |
| Díaz, FV; Rasgado, LA; Reyes, GC | 1 |
| Koshal, P; Kumar, P | 1 |
| Goel, RK; Singh, T | 1 |
| López-Pérez, S; Medina-Ceja, L; Morales-Villagrán, A; Pardo-Peña, K | 1 |
| Kumar, M; Kumar, P | 1 |
| Arzhang, A; Elahdadi Salmani, M; Goudarzi, I; Lashkarbolouki, T | 1 |
| Barbieri Caus, L; Calcagnotto, ME; Ganzella, M; Gomes de Souza, DO; Goodman, S; Junges, B; Koeller, DM; Loureiro, S; Meier, L; Umpierrez Amaral, A; Vendramin Pasquetti, M; Wajner, M; Woontner, M | 1 |
| Amin, F; Arain, FM; Chand, P; Dar, AH; Haider, G; Khan, F; Mitha, R; Osama, K; Tharwani, A | 1 |
| Bi, Y; Ding, L; Gao, W; Ye, M; Zhu, W | 1 |
| Dehpour, AR; Ejtemaei Mehr, S; Esmaeili, J; Ghahremani, MH; Mohammad Jafari, R; Rahimi, N; Rashidian, A; Shadboorestan, A | 1 |
| Huang, Q; Huang, Y; Liao, Y; Liu, X; Wei, X; Wu, Y; Zou, D | 1 |
| Aghaei, I; Bahramnjead, E; Dehpour, AR; Etemadi, P; Kazemi Roodsari, S; Rahimi, N | 1 |
| Choo, BKM; Johan Arief, MFB; Kumari, Y; Kundap, UP; Othman, I; Shaikh, MF; Wong, CP; Yap, JL | 1 |
| Bahramnejad, E; Dehpour, AR; Faghir-Ghanesefat, H; Hassanipour, M; Pourshadi, N; Rahimi, N; Yarmohammadi, F | 1 |
| Bao, G; Chen, X; Liu, F | 1 |
| Alese, OO; Mabandla, MV; Mkhize, NV; Ngoupaye, GT; Rakgantsho, C; Zulu, S | 1 |
| Ciltas, AC; Güneş, H; Toy, CE; Yaprak, M | 1 |
| Banono, NS; Esguerra, CV; Gawel, K; Kaczor, AA; Kukula-Koch, W; Nieoczym, D; Stępnik, K; Szybkowski, P | 1 |
90 other study(ies) available for pentylenetetrazole and glutamic acid
| Article | Year |
|---|---|
Dipeptides--analogues of N-acetylaspartylglutamate inhibit convulsive effects of excitatory amino acids in mice.
Topics: Animals; Cerebral Ventricles; Dipeptides; Glutamates; Glutamic Acid; Injections, Intraventricular; Kainic Acid; Mice; Mice, Inbred Strains; N-Methylaspartate; Neurotoxins; Pentylenetetrazole; Seizures; Structure-Activity Relationship | 1991 |
The role of GABA and excitatory amino acids in the development of the leptazol-induced epileptogenic EEG.
Topics: Allylglycine; Amino Acids; Animals; Bicuculline; Cerebral Cortex; Clonazepam; Dose-Response Relationship, Drug; Electroencephalography; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Male; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Seizures; Time Factors; Valproic Acid | 1986 |
CGS 19755, a selective and competitive N-methyl-D-aspartate-type excitatory amino acid receptor antagonist.
Topics: Acetylcholine; Aconitine; Animals; Anticonvulsants; Aspartic Acid; Avoidance Learning; Binding, Competitive; Darkness; Glutamates; Glutamic Acid; Male; N-Methylaspartate; Pentylenetetrazole; Picrotoxin; Pipecolic Acids; Piperidines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Structure-Activity Relationship; Tetrodotoxin | 1988 |
Potentiation of metrazol convulsions in chickens after neonatal injections of cycloheximide or glutamate.
Topics: Animals; Chickens; Cycloheximide; Dose-Response Relationship, Drug; Drug Synergism; Glutamates; Glutamic Acid; Male; Pentylenetetrazole; Premedication; Seizures | 1982 |
Excitatory amino acid receptor interactions of a novel alpha-phosphinic acid analogue of alpha-methylaspartic acid.
Topics: Acetylcholine; Alanine; Animals; Anticonvulsants; Aspartic Acid; Cerebellum; Corpus Striatum; Electroshock; Glutamates; Glutamic Acid; In Vitro Techniques; Organophosphorus Compounds; Pentylenetetrazole; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Synaptosomes | 1984 |
Chronic administration of a nitric oxide synthase inhibitor, N omega-nitro-L-arginine, and drug-induced increase in cerebellar cyclic GMP in vivo.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cerebellum; Cyclic GMP; Drug Interactions; Glutamates; Glutamic Acid; Harmaline; Male; Mice; Nitric Oxide Synthase; Nitroarginine; Pentylenetetrazole; Picrotoxin | 1993 |
Cardiorespiratory alterations produced by pharmacological agents applied to the ventrolateral medulla (intermediate area) of the cat. Effect of exercise condition on glycine-induced inhibition.
Topics: Animals; Blood Pressure; Cats; Electric Stimulation; Female; Glutamates; Glutamic Acid; Glycine; Heart Rate; Male; Medulla Oblongata; Oxygen Consumption; Pentobarbital; Pentylenetetrazole; Respiration; Rest; Time Factors | 1993 |
Picrotoxin and pentylene tetrazole induced seizure activity in pyridoxine-deficient rats.
Topics: Animals; Cerebral Cortex; Differential Threshold; Electroencephalography; Electronic Data Processing; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Male; Neurons; Pentylenetetrazole; Picrotoxin; Pyridoxine; Rats; Rats, Sprague-Dawley; Seizures; Thalamus; Vitamin B 6 Deficiency | 1994 |
Specific [3H]L-glutamate binding and [3H]D-aspartate release in the hippocampus of rat after pentylenetetrazol kindling and long-term potentiation.
Topics: Animals; Aspartic Acid; Glutamates; Glutamic Acid; Hippocampus; Kindling, Neurologic; Kinetics; Long-Term Potentiation; Male; Pentylenetetrazole; Rats; Rats, Wistar; Reference Values; Time Factors; Tritium | 1994 |
Glutamate binding to brain membranes is increased in pentylenetetrazole-kindled rats.
Topics: Animals; Brain; Glutamates; Glutamic Acid; Hippocampus; Kindling, Neurologic; Kinetics; Male; Pentylenetetrazole; Rats; Rats, Wistar; Reference Values; Synaptosomes; Tissue Distribution | 1993 |
N omega-nitro-L-arginine methyl ester interferes with pentylenetetrazol-induced kindling and has no effect on changes in glutamate binding.
Topics: Animals; Arginine; Convulsants; Enzyme Inhibitors; Glutamic Acid; Kindling, Neurologic; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pentylenetetrazole; Rats | 1995 |
Excitatory amino acid antagonists and pentylenetetrazol-induced seizures during ontogenesis: III. The action of kynurenic acid and glutamic acid diethylester.
Topics: Age Factors; Animals; Disease Models, Animal; Glutamic Acid; Kynurenic Acid; Male; Pentylenetetrazole; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures | 1995 |
Regional excitatory and inhibitory amino acid concentrations in pentylenetetrazol kindling and kindled rat brain.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brain Chemistry; Convulsants; gamma-Aminobutyric Acid; Glutamic Acid; Kindling, Neurologic; Male; Neural Inhibition; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Taurine | 1997 |
Glutamate transporter EAAC-1-deficient mice develop dicarboxylic aminoaciduria and behavioral abnormalities but no neurodegeneration.
Topics: Amino Acid Sequence; Amino Acid Transport System X-AG; Amino Acids, Dicarboxylic; Animals; Brain; Carrier Proteins; Epilepsy; Excitatory Amino Acid Transporter 1; Female; Gene Targeting; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Motor Activity; Pentylenetetrazole; Phenotype; Rats; Symporters | 1997 |
Strain differences in pentylenetetrazol-kindling development and subsequent potentiation effects.
Topics: Animals; Convulsants; Disease Models, Animal; Epilepsy; Glutamic Acid; Kindling, Neurologic; Male; Pentylenetetrazole; Rats; Rats, Wistar | 1997 |
Sensitisation to repeated withdrawal, in mice treated chronically with diazepam, is blocked by an NMDA receptor antagonist.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anti-Anxiety Agents; Convulsants; Diazepam; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Pentylenetetrazole; Receptors, N-Methyl-D-Aspartate; Seizures; Substance Withdrawal Syndrome; Synaptic Transmission | 1998 |
A neuropharmacological analysis of PTZ-induced kindling in mice.
Topics: Aging; Animals; Anticonvulsants; Convulsants; Diazepam; Glutamic Acid; Kindling, Neurologic; Male; Membranes; Mice; Pentylenetetrazole; Phenobarbital | 1998 |
Sensitivity and density of glutamate receptor subtypes in the hippocampal formation are altered in pentylenetetrazole-kindled rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Brain Chemistry; Convulsants; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Inositol Phosphates; Kindling, Neurologic; Male; Neuroprotective Agents; Pentylenetetrazole; Radioligand Assay; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Tritium | 1998 |
Excitotoxin-induced neuronal death is associated with response of a unique intracellular aspartic proteinase, cathepsin E.
Topics: Animals; Blotting, Northern; Cathepsin D; Cathepsin E; Cell Survival; Cells, Cultured; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; Immunohistochemistry; Intracellular Membranes; Kainic Acid; Male; Neurons; Neurotoxins; Pentylenetetrazole; Rats; Rats, Wistar; RNA, Messenger | 1998 |
Galanin controls excitability of the brain.
Topics: Animals; Brain; Cerebral Ventricles; Convulsants; Galanin; Glutamic Acid; Injections, Intraventricular; Male; Pentylenetetrazole; Rats; Seizures; Substance P | 1998 |
3H-L-glutamate binding and 3H-D-aspartate release from hippocampal tissue during the development of pentylenetetrazole kindling in rats.
Topics: Animals; Aspartic Acid; GABA Antagonists; Glutamic Acid; Hippocampus; Kindling, Neurologic; Male; Pentylenetetrazole; Rats; Rats, Wistar; Synaptic Membranes; Tritium | 1999 |
Effects of enadoline on the development of pentylenetetrazol kindling, learning performance, and hippocampal morphology.
Topics: Animals; Benzofurans; Convulsants; Glutamic Acid; Hippocampus; Kindling, Neurologic; Learning; Male; Pentylenetetrazole; Pyrrolidines; Rats; Rats, Wistar; Seizures | 1999 |
Cerebral seizure susceptibility and patterns of paroxysmal activity during embryonic development in the domestic chicken.
Topics: Animals; Anticonvulsants; Chick Embryo; Convulsants; Electroencephalography; Glutamic Acid; Methionine Sulfoximine; Ouabain; Pentylenetetrazole; Phenytoin; Seizures | 1973 |
Anticonvulsant properties of linalool in glutamate-related seizure models.
Topics: Acyclic Monoterpenes; Animals; Anticonvulsants; Cerebral Cortex; Disease Models, Animal; Dizocilpine Maleate; Glutamic Acid; Kindling, Neurologic; Male; Monoterpenes; N-Methylaspartate; Pentylenetetrazole; Phenobarbital; Quinolinic Acid; Radioligand Assay; Rats; Rats, Wistar; Seizures; Terpenes | 1999 |
Involvement of delta-opioid receptors in pentylenetetrazol kindling development and kindling-related processes in rats.
Topics: Animals; Convulsants; Drug Interactions; Glutamic Acid; Injections, Intraventricular; Kindling, Neurologic; Learning Disabilities; Male; Naltrexone; Narcotic Antagonists; Pentylenetetrazole; Rats; Rats, Wistar; Receptors, Opioid, delta; Seizures; Time Factors | 1999 |
Polyunsaturated fatty acids modify mouse hippocampal neuronal excitability during excitotoxic or convulsant stimulation.
Topics: Action Potentials; Animals; Convulsants; Docosahexaenoic Acids; Eicosapentaenoic Acid; Epilepsy; Fatty Acids, Unsaturated; Glutamic Acid; Hippocampus; Male; Mice; Neurons; Neurotoxins; Oleic Acid; Patch-Clamp Techniques; Pentylenetetrazole; Platelet Aggregation Inhibitors; Stearic Acids | 1999 |
Expression of neuropeptide Y by glutamatergic stimulation in rat C6 glioma cells.
Topics: Animals; Dopamine; Gene Expression Regulation, Neoplastic; Glioma; Glutamic Acid; Haloperidol; Kainic Acid; Muscimol; Neuropeptide Y; Pentylenetetrazole; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 2000 |
Upregulation of NMDA receptors in hippocampus and cortex in the pentylenetetrazol-induced "kindling" model of epilepsy.
Topics: Animals; Autoradiography; Dentate Gyrus; Dizocilpine Maleate; Epilepsy; Glutamic Acid; Hippocampus; Kindling, Neurologic; Male; Mice; Mice, Inbred BALB C; Pentylenetetrazole; Pyramidal Cells; Receptors, N-Methyl-D-Aspartate; Reference Values; Tritium; Up-Regulation | 1999 |
In vitro and in vivo characterization of conantokin-R, a selective NMDA receptor antagonist isolated from the venom of the fish-hunting snail Conus radiatus.
Topics: Animals; Anticonvulsants; Behavior, Animal; Binding, Competitive; Cerebral Cortex; Conotoxins; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Evoked Potentials; Female; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Kainic Acid; Male; Mice; Mollusk Venoms; Oocytes; Pentylenetetrazole; Piperidines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Seizures; Sound; Xenopus | 2000 |
The effect of pentylenetetrazole-kindling on the extracellular glutamate and taurine levels in the frontal cortex of rats.
Topics: Animals; Convulsants; Extracellular Space; Frontal Lobe; Glutamic Acid; Kindling, Neurologic; Male; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures; Taurine | 2000 |
Effects of ammonia on pentylenetetrazole-induced seizure threshold.
Topics: Ammonia; Animals; Aspartic Acid; Brain; Dose-Response Relationship, Drug; Drug Interactions; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glycine; Hepatic Encephalopathy; Linear Models; Male; Neurons; Pentylenetetrazole; Rats; Rats, Wistar; Seizures | 1999 |
Seizures induce simultaneous GABAergic and glutamatergic transmission in the dentate gyrus-CA3 system.
Topics: Amygdala; Animals; Dentate Gyrus; Electric Stimulation; Electrodes, Implanted; Epilepsy; Evoked Potentials; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Kindling, Neurologic; Neural Inhibition; Pentylenetetrazole; Pyramidal Cells; Rats; Rats, Wistar; Reaction Time; Seizures; Synapses; Synaptic Transmission | 2000 |
Antiepileptogenic properties of phenobarbital: behavior and neurochemical analysis.
Topics: Animals; Anticonvulsants; Cerebral Cortex; Convulsants; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Mice; Pentylenetetrazole; Phenobarbital; Seizures | 2000 |
Effects of pentylenetetrazole and glutamate on metabolism of [U-(13)C]glucose in cultured cerebellar granule neurons.
Topics: Alanine; Animals; Aspartic Acid; Cells, Cultured; Cerebellum; Convulsants; Glucose; Glutamic Acid; Lactates; Magnetic Resonance Spectroscopy; Mice; Neurons; Pentylenetetrazole | 2002 |
Decreased synaptic vesicle recycling efficiency and cognitive deficits in amphiphysin 1 knockout mice.
Topics: Animals; Cerebral Cortex; Clathrin; Conditioning, Classical; Endocytosis; Fluorescent Dyes; GABA Antagonists; Glutamic Acid; Humans; Maze Learning; Mice; Mice, Knockout; Nerve Tissue Proteins; Neurons; Pentylenetetrazole; Protein Isoforms; Pyridinium Compounds; Quaternary Ammonium Compounds; Survival Rate; Synaptic Vesicles | 2002 |
Pentylenetetrazole decreases metabolic glutamate turnover in rat brain.
Topics: Animals; Brain; Brain Chemistry; Carbon Isotopes; Cerebellum; Cerebral Cortex; Chromatography, High Pressure Liquid; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Magnetic Resonance Spectroscopy; Male; Pentylenetetrazole; Rats; Rats, Wistar; Seizures | 2003 |
Neurochemical characteristics of the ventromedial hypothalamus in mediating the antiaversive effects of anxiolytics in different models of anxiety.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Apomorphine; Avoidance Learning; Biguanides; Brain Chemistry; Chlordiazepoxide; Clonidine; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Droperidol; Drug Interactions; GABA Agents; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Glutamic Acid; Male; Memantine; Mephenytoin; Microinjections; Pentylenetetrazole; Phentolamine; Picrotoxin; Piperazines; Propranolol; Pyrimidines; Rats; Serotonin; Sulpiride; Ventromedial Hypothalamic Nucleus; Yohimbine | 2003 |
Is the interaction between felbamate and valproate against seizures induced by 4-aminopyridine and pentylenetetrazole in mice beneficial?
Topics: 4-Aminopyridine; Analysis of Variance; Animals; Brain; Chromatography, Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Felbamate; gamma-Aminobutyric Acid; Glutamic Acid; Male; Mice; Mice, Inbred Strains; Neurotoxicity Syndromes; Pentylenetetrazole; Phenylcarbamates; Propylene Glycols; Reaction Time; Seizures; Toxicity Tests; Valproic Acid | 2003 |
Overexpression of spermidine/spermine N1-acetyltransferase elevates the threshold to pentylenetetrazol-induced seizure activity in transgenic mice.
Topics: Acetyltransferases; Animals; Biogenic Polyamines; Brain; Cell Count; Crosses, Genetic; Dose-Response Relationship, Drug; Drug Resistance; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Mice, Transgenic; Neurons; Pentylenetetrazole; Piperidines; Putrescine; Seizures | 2003 |
Elevation of corazol-induced seizure threshold after active immunization of mice of various genetic strains with glutamate-bovine serum albumin conjugate.
Topics: Animals; Anticonvulsants; Cattle; Convulsants; Glutamic Acid; Glutamine; Immunization; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Pentylenetetrazole; Seizures; Serum Albumin, Bovine; Species Specificity; Surgical Flaps | 2003 |
Effect of valproic acid on levels of GABA and glutamic acid in pentylenetetrazole-damaged rat brain.
Topics: Animals; Anticonvulsants; Body Weight; Brain Chemistry; Convulsants; gamma-Aminobutyric Acid; Glutamic Acid; Male; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Valproic Acid | 2003 |
Accelerated kindling development in mu-opioid receptor deficient mice.
Topics: Animals; Brain; Dose-Response Relationship, Drug; Glutamic Acid; Kindling, Neurologic; Male; Mice; Mice, Knockout; Pentylenetetrazole; Protein Binding; Receptors, Opioid, mu | 2004 |
Inhibitory effects of the essential oil from SuHeXiang Wan on the central nervous system after inhalation.
Topics: 4-Aminobutyrate Transaminase; Administration, Inhalation; Animals; Anticonvulsants; Antioxidants; Brain; Brain Chemistry; Drugs, Chinese Herbal; Glutamic Acid; Lipid Peroxidation; Male; Mice; Mice, Inbred ICR; Oils, Volatile; Pentylenetetrazole; Phytotherapy; Picrotoxin; Receptors, GABA-A; Seizures; Sleep; Strychnine | 2004 |
In vivo measurement of brain extracellular space diffusion by cortical surface photobleaching.
Topics: Animals; Aquaporin 4; Aquaporins; Astrocytes; Brain Edema; Cerebral Cortex; Convulsants; Dextrans; Diffusion; Dura Mater; Electroencephalography; Extracellular Space; Fluorescein-5-isothiocyanate; Fluorescence Recovery After Photobleaching; Fluorescent Dyes; Glutamic Acid; Instillation, Drug; Lasers; Male; Mice; Mice, Knockout; Molecular Weight; Pentylenetetrazole; Photobleaching; Seizures; Water Intoxication | 2004 |
Beneficial interaction between vigabatrin and valproate against seizures induced by pentylenetetrazole in mice.
Topics: Animals; Anticonvulsants; Brain; Convulsants; Drug Synergism; gamma-Aminobutyric Acid; Glutamic Acid; Male; Mice; Pentylenetetrazole; Valproic Acid; Vigabatrin | 2005 |
Chronic treatment with fluoxetine decreases seizure threshold in naïve but not in rats exposed to the learned helplessness paradigm: Correlation with the hippocampal glutamate release.
Topics: Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Convulsants; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fluoxetine; Glutamic Acid; Helplessness, Learned; Hippocampus; In Vitro Techniques; Male; Pentylenetetrazole; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures; Synaptic Transmission | 2005 |
Target-specific catecholamine elevation induced by anticonvulsant thalamic deep brain stimulation.
Topics: Animals; Brain; Catecholamines; Chromatography, High Pressure Liquid; Deep Brain Stimulation; Disease Models, Animal; Electrodes, Implanted; Electroencephalography; gamma-Aminobutyric Acid; Glutamic Acid; Male; Microdialysis; Pentylenetetrazole; Random Allocation; Rats; Seizures; Stereotaxic Techniques; Thalamus; Tissue Distribution | 2005 |
Agmatine reduces extracellular glutamate during pentylenetetrazole-induced seizures in rat brain: a potential mechanism for the anticonvulsive effects.
Topics: Agmatine; Animals; Brain; Chromatography, High Pressure Liquid; Disease Models, Animal; Drug Interactions; Extracellular Space; Glutamic Acid; Male; Microdialysis; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures; Time Factors | 2005 |
Systemic administration of antibodies to glutamate increases seizure threshold for pentylenetetrazole.
Topics: Animals; Antibodies; Anticonvulsants; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Pentylenetetrazole; Seizures; Serum Albumin, Bovine | 2005 |
[Saikosaponins inhibit increased glutamate and GABA expressions in the hippocampus of pentetrazole-induced slow kindling rats].
Topics: Animals; Female; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Immunohistochemistry; Kindling, Neurologic; Male; Oleanolic Acid; Pentylenetetrazole; Random Allocation; Rats; Rats, Sprague-Dawley; Saponins | 2006 |
Effect of systemic treatment with antibodies against glutamate on the seizure response of C57Bl/6 mice after pentylenetetrazole kindling.
Topics: Animals; Antibodies; Anticonvulsants; Glutamic Acid; Kindling, Neurologic; Male; Mice; Mice, Inbred C57BL; Pentylenetetrazole; Rabbits; Seizures | 2007 |
Knock-in mice lacking the PDZ-ligand motif of mGluR7a show impaired PKC-dependent autoinhibition of glutamate release, spatial working memory deficits, and increased susceptibility to pentylenetetrazol.
Topics: Amino Acid Motifs; Animals; Behavior, Animal; Brain; Carrier Proteins; Cell Cycle Proteins; Cells, Cultured; Cerebellum; Convulsants; Excitatory Amino Acid Antagonists; Genetic Predisposition to Disease; Glutamic Acid; Ligands; Memory Disorders; Mice; Mice, Transgenic; Mutation; Neural Inhibition; Nuclear Proteins; Oocytes; Pentylenetetrazole; Presynaptic Terminals; Protein Isoforms; Protein Kinase C; Receptors, Metabotropic Glutamate; Seizures; Signal Transduction; Space Perception; Synapses; Xenopus laevis | 2008 |
Tyrianthinic acids from Ipomoea tyrianthina and their antimycobacterial activity, cytotoxicity, and effects on the central nervous system.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antitubercular Agents; Central Nervous System; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Ipomoea; KB Cells; Mexico; Mice; Models, Animal; Oligosaccharides; Pentobarbital; Pentylenetetrazole; Plant Roots; Plants, Medicinal; Tuberculosis | 2008 |
Rats harboring S284L Chrna4 mutation show attenuation of synaptic and extrasynaptic GABAergic transmission and exhibit the nocturnal frontal lobe epilepsy phenotype.
Topics: Age Factors; Analysis of Variance; Animals; Behavior, Animal; Cerebral Cortex; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Frontal Lobe; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hot Temperature; In Vitro Techniques; Leucine; Microscopy, Immunoelectron; Motor Activity; Motor Skills; Mutation; Neurotransmitter Agents; Nicotine; Pain Measurement; Pentylenetetrazole; Phenotype; Rats; Rats, Transgenic; Receptors, Nicotinic; Serine; Synaptic Transmission | 2008 |
Swimming training prevents pentylenetetrazol-induced inhibition of Na+, K+-ATPase activity, seizures, and oxidative stress.
Topics: Analysis of Variance; Animals; Behavior, Animal; Body Weight; Catalase; Disease Models, Animal; Electroencephalography; Exercise Therapy; Fluoresceins; Glutamic Acid; Male; Oxidative Stress; Pentylenetetrazole; Protein Carbonylation; Rats; Rats, Wistar; Reaction Time; Reactive Oxygen Species; Seizures; Sodium-Potassium-Exchanging ATPase; Statistics as Topic; Superoxide Dismutase; Swimming; Thiobarbituric Acid Reactive Substances | 2009 |
Role of glutamate and GABA transporters in development of pentylenetetrazol-kindling.
Topics: Animals; Blotting, Western; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; GABA Plasma Membrane Transport Proteins; Glutamic Acid; Kindling, Neurologic; Pentylenetetrazole; Rats; Rats, Sprague-Dawley | 2009 |
The effects of group III mGluR ligands on pentylenetetrazol-induced kindling of seizures and hippocampal amino acids concentration.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Kindling, Neurologic; Male; Pentylenetetrazole; Rats; Receptors, Metabotropic Glutamate; Taurine | 2009 |
Neuron-glia communication via EphA4/ephrin-A3 modulates LTP through glial glutamate transport.
Topics: Animals; Animals, Newborn; Aspartic Acid; Biophysics; Disease Models, Animal; Electric Stimulation; Ephrin-A3; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 1; Excitatory Postsynaptic Potentials; Glial Fibrillary Acidic Protein; Glutamic Acid; Green Fluorescent Proteins; Hippocampus; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuroglia; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Pentylenetetrazole; Receptor, EphA4; Seizures; Signal Transduction; Synapses; Up-Regulation | 2009 |
Efficacy of 3,5-dibromo-L-phenylalanine in rat models of stroke, seizures and sensorimotor gating deficit.
Topics: Animals; Disease Models, Animal; Dizocilpine Maleate; Endothelin-1; Gait Disorders, Neurologic; Glutamic Acid; Male; Pentylenetetrazole; Phenylalanine; Rats; Rats, Sprague-Dawley; Reflex, Startle; Seizures; Stroke | 2009 |
[Effect of Chaihu Shugan Tang on excitability in different brain regions of pentylenetetrazole-kindled chronic epileptic rats].
Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Aspartic Acid; Brain; Chronic Disease; Deoxyglucose; Disease Models, Animal; Drugs, Chinese Herbal; Epilepsy; Glutamic Acid; Hippocampus; Humans; Kindling, Neurologic; Male; Pentylenetetrazole; Random Allocation; Rats; Valproic Acid | 2010 |
Differential molecular regulation of glutamate in kindling resistant rats.
Topics: Animals; Convulsants; DNA Primers; Electric Stimulation; Epilepsy, Tonic-Clonic; Glutamic Acid; Hippocampus; Kindling, Neurologic; Male; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Reverse Transcription; RNA, Messenger; Seizures; Stimulation, Chemical | 2011 |
Study of epileptiform activity in cerebral ganglion of mud crab Scylla serrata.
Topics: Animals; Anticonvulsants; Brachyura; Convulsants; Disease Models, Animal; Epilepsy; gamma-Aminobutyric Acid; Ganglia, Invertebrate; Glutamic Acid; Neurons; Pentylenetetrazole; Valproic Acid | 2011 |
Chronic h1-antihistamine treatment increases seizure susceptibility after withdrawal by impairing glutamine synthetase.
Topics: Animals; Astrocytes; Blotting, Western; Chromatography, High Pressure Liquid; Convulsants; Electroshock; gamma-Aminobutyric Acid; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Histamine H1 Antagonists; Histidine Decarboxylase; Immunohistochemistry; Kindling, Neurologic; Male; Methionine Sulfoximine; Mice; Mice, Inbred C57BL; Mice, Knockout; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures; Substance Withdrawal Syndrome | 2012 |
Decreased susceptibility to seizures induced by pentylenetetrazole in serine racemase knockout mice.
Topics: Amino Acids; Analysis of Variance; Animals; Brain; Chromatography, High Pressure Liquid; Convulsants; Disease Models, Animal; Disease Susceptibility; Dose-Response Relationship, Drug; Genetic Predisposition to Disease; Glutamic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; Microdialysis; Microscopy, Confocal; Pentylenetetrazole; Proto-Oncogene Proteins c-fos; Racemases and Epimerases; Seizures; Statistics, Nonparametric; Time Factors | 2012 |
ONO-2506 inhibits spike-wave discharges in a genetic animal model without affecting traditional convulsive tests via gliotransmission regulation.
Topics: Animals; Anticonvulsants; Astrocytes; Caprylates; Cells, Cultured; Convulsants; Disease Models, Animal; Electroshock; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Kynurenic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Pentylenetetrazole; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Serine; Synaptic Transmission | 2013 |
Comparison and effects of acute lamotrigine treatment on extracellular excitatory amino acids in the hippocampus of PTZ-kindled epileptic and PTZ-induced status epilepticus rats.
Topics: Animals; Aspartic Acid; Epilepsy; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Kindling, Neurologic; Lamotrigine; Male; Neurotransmitter Agents; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Status Epilepticus; Triazines | 2013 |
L-Theanine intake increases threshold for limbic seizures but decreases threshold for generalized seizures.
Topics: Animals; Disease Models, Animal; GABA Agents; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; Male; Mice; Mice, Inbred Strains; Microdialysis; Pentylenetetrazole; Pilocarpine; Seizures; Tea | 2013 |
[Effects of heterotherapy for homopathy on the metabolism path of glutamate in the pentylenetetrazol-kindled seizure rats' hippocampus].
Topics: Animals; Excitatory Amino Acid Transporter 2; Glutamic Acid; Hippocampus; Kindling, Neurologic; Male; Medicine, Chinese Traditional; Pentylenetetrazole; Rats; Rats, Wistar; Seizures | 2013 |
Elevation of seizure threshold after intranasal administration of anti-glutamate antibodies to C57BL/6 mice.
Topics: Administration, Intranasal; Animals; Antibodies; Anticonvulsants; Dose-Response Relationship, Drug; Glutamic Acid; Injections, Intraperitoneal; Mice; Mice, Inbred C57BL; Pentylenetetrazole; Rats; Rats, Wistar; Seizures | 2013 |
Antiepileptic potential of matrine via regulation the levels of gamma-aminobutyric acid and glutamic acid in the brain.
Topics: Alkaloids; Animals; Anticonvulsants; Aspartic Acid; Brain; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Glycine; Male; Matrines; Mice; Mice, Inbred ICR; Motor Activity; Pentylenetetrazole; Quinolizines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Seizures; Up-Regulation | 2013 |
JM-20, a novel benzodiazepine–dihydropyridine hybrid molecule, protects mitochondria and prevents ischemic insult-mediated neural cell death in vitro.
Topics: Animals; Benzodiazepines; Brain Ischemia; Calcium; Cell Death; Cerebellum; Cytochromes c; Dihydropyridines; Glutamic Acid; Hydrogen Peroxide; Hydrolysis; Liver; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Proton-Translocating ATPases; Mitochondrial Swelling; Neurons; Neuroprotective Agents; Niacin; Oxidative Stress; PC12 Cells; Pentylenetetrazole; Phosphates; Potassium Cyanide; Rats; Stroke | 2014 |
Hippocampal orexin receptors inactivation reduces PTZ induced seizures of male rats.
Topics: Animals; Benzoxazoles; Convulsants; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Isoquinolines; Male; Microinjections; Naphthyridines; Orexin Receptor Antagonists; Orexin Receptors; Pentylenetetrazole; Pyridines; Rats; Seizures; Urea | 2015 |
Modulation of brain glutamate dehydrogenase as a tool for controlling seizures.
Topics: Animals; Anticonvulsants; Brain; Deamination; Diazepam; Disease Models, Animal; Enzyme Inhibitors; Glutamate Dehydrogenase; Glutamic Acid; Ketoglutaric Acids; Male; Mice; Oxidation-Reduction; Oxygen Consumption; Pentylenetetrazole; Phenytoin; Seizures; Time Factors; Valproic Acid | 2015 |
Neurochemical modulation involved in the beneficial effect of liraglutide, GLP-1 agonist on PTZ kindling epilepsy-induced comorbidities in mice.
Topics: Animals; Comorbidity; Epilepsy; gamma-Aminobutyric Acid; Glucagon-Like Peptide 1; Glutamic Acid; Glutathione; Kindling, Neurologic; Liraglutide; Male; Mice; Nitrites; Pentylenetetrazole | 2016 |
Evidence in support of using a neurochemistry approach to identify therapy for both epilepsy and associated depression.
Topics: Animals; Anticonvulsants; Brain; Depression; Depressive Disorder; Disease Models, Animal; Dopamine; Epilepsy; Glutamic Acid; Hindlimb Suspension; Kindling, Neurologic; Male; Mice; Neurochemistry; Norepinephrine; Pentylenetetrazole; Seizures; Serotonin; Treatment Outcome; Valproic Acid | 2016 |
A microdialysis and enzymatic reactor sensing procedure for the simultaneous registration of online glutamate measurements at high temporal resolution during epileptiform activity.
Topics: Animals; Electroencephalography; Glutamic Acid; Hippocampus; Male; Microdialysis; Pentylenetetrazole; Rats; Rats, Wistar; Seizures | 2016 |
Protective effect of spermine against pentylenetetrazole kindling epilepsy induced comorbidities in mice.
Topics: Animals; Arginine; Avoidance Learning; Brain; Catecholamines; Comorbidity; Depression; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Kindling, Neurologic; Male; Mice; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Pentylenetetrazole; Spermine | 2017 |
Posterior hypothalamus glutamate infusion decreases pentylenetetrazol-induced seizures of male rats through hippocampal histamine increase.
Topics: Animals; Glutamic Acid; Histamine Release; Hypothalamus; Male; Pentylenetetrazole; Rats; Rats, Wistar; Seizures | 2017 |
Impairment of GABAergic system contributes to epileptogenesis in glutaric acidemia type I.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Blotting, Western; Brain; Brain Diseases, Metabolic; Chromatography, High Pressure Liquid; Epilepsy; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Glutaryl-CoA Dehydrogenase; Mice; Mice, Knockout; Pentylenetetrazole; Synaptosomes | 2017 |
A species dependent response to the pro-epileptic drug pentylentetrazole in birds.
Topics: Animals; Convulsants; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamic Acid; Immunohistochemistry; Myoclonus; Neurons; Parrots; Pentylenetetrazole; Phenotype; Seizures; Sparrows; Species Specificity; Telencephalon | 2017 |
SSa ameliorates the Glu uptaking capacity of astrocytes in epilepsy via AP-1/miR-155/GLAST.
Topics: Animals; Astrocytes; Disease Models, Animal; Epilepsy; Excitatory Amino Acid Transporter 1; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; MicroRNAs; Oleanolic Acid; Pentylenetetrazole; Proto-Oncogene Proteins c-fos; Rats, Wistar; Saponins; Transcription Factor AP-1 | 2017 |
The anticonvulsant activity and cerebral protection of chronic lithium chloride via NMDA receptor/nitric oxide and phospho-ERK.
Topics: Animals; Anticonvulsants; Cells, Cultured; Cerebellum; Cerebral Cortex; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Lithium Chloride; Male; MAP Kinase Signaling System; Mice; Neurons; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase Type I; Pentylenetetrazole; Phosphorylation; Receptors, N-Methyl-D-Aspartate; Seizures | 2018 |
Role of miR-34c in the cognitive function of epileptic rats induced by pentylenetetrazol.
Topics: Animals; Cognition; Disease Models, Animal; Epilepsy, Temporal Lobe; Gene Expression Regulation; Glutamic Acid; Hippocampus; Long-Term Potentiation; Male; Maze Learning; Memory; MicroRNAs; Oligoribonucleotides; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2018 |
Effects of Modafinil on Clonic Seizure Threshold Induced by Pentylenetetrazole in Mice: Involvement of Glutamate, Nitric oxide, GABA, and Serotonin Pathways.
Topics: Animals; Anticonvulsants; Enzyme Inhibitors; Glutamic Acid; Indazoles; Male; Mice; Modafinil; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Pentylenetetrazole; Seizures; Serotonin | 2018 |
Effect of newer anti-epileptic drugs (AEDs) on the cognitive status in pentylenetetrazol induced seizures in a zebrafish model.
Topics: Acetylcholine; Animals; Anticonvulsants; Brain; Brain-Derived Neurotrophic Factor; Cognitive Dysfunction; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Drug Interactions; gamma-Aminobutyric Acid; Gene Expression; Glutamic Acid; Locomotion; Maze Learning; Neuropeptide Y; Pentylenetetrazole; Seizures; Zebrafish | 2019 |
Nitric oxide and glutamate are contributors of anti-seizure activity of rubidium chloride: A comparison with lithium.
Topics: Animals; Anticonvulsants; Chlorides; Glutamic Acid; Lithium Chloride; Male; Mice; Neuroprotective Agents; Nitric Oxide; Pentylenetetrazole; Receptors, N-Methyl-D-Aspartate; Rubidium; Seizures; Signal Transduction | 2019 |
Inhibition of USP15 Prevent Glutamate-Induced Oxidative Damage by Activating Nrf2/HO-1 Signaling Pathway in HT22 Cells.
Topics: Animals; Cell Death; Cell Line; Endopeptidases; Glutamic Acid; Heme Oxygenase-1; Kindling, Neurologic; Male; Mice; Neuroprotection; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Pentylenetetrazole; Rats, Sprague-Dawley; Signal Transduction; Ubiquitin-Specific Proteases; Up-Regulation | 2020 |
Glutamatergic pathway in depressive-like behavior associated with pentylenetetrazole rat model of epilepsy with history of prolonged febrile seizures.
Topics: Amygdala; Animals; Brain-Derived Neurotrophic Factor; Depression; Epilepsy; Excitatory Amino Acid Transporter 1; Glutamate Synthase; Glutamic Acid; Hippocampus; Male; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Seizures, Febrile | 2020 |
Effects of probiotics on GABA/glutamate and oxidative stress in PTZ- induced acute seizure model in rats.
Topics: Animals; Anticonvulsants; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Male; Oxidative Stress; Pentylenetetrazole; Probiotics; Rats; Rats, Wistar; Seizures | 2023 |
In Silico Analysis, Anticonvulsant Activity, and Toxicity Evaluation of Schisandrin B in Zebrafish Larvae and Mice.
Topics: Animals; Anticonvulsants; Glutamic Acid; Larva; Mice; Molecular Docking Simulation; Pentylenetetrazole; Receptors, GABA-A; Seizures; Zebrafish | 2023 |