Page last updated: 2024-08-17

pentylenetetrazole and gabapentin

pentylenetetrazole has been researched along with gabapentin in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.76)18.2507
2000's9 (42.86)29.6817
2010's9 (42.86)24.3611
2020's2 (9.52)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Haugvicová, R; Mares, P1
Bruins Slot, LA; Colpaert, FC; Koek, W; Ribet, JP; Tarayre, JP1
Czuczwar, SJ; Luszczki, JJ2
Acosta, GB; Baratti, CM; Blake, MG; Boccia, MM1
Dos Santos, RG; Dotsikas, I; Felix, R; Kolocouris, N; Papadopoulou-Daifoti, Z; Papanastasiou, I; Sandoval, A; Vamvakides, A; Zoidis, G1
Kumar, M; Rehni, AK; Singh, I1
Czuczwar, SJ; Luszczki, JJ; Patsalos, PN; Ratnaraj, N1
Andres-Mach, MM; Czuczwar, SJ; Dudra-Jastrzebska, M; Luszczki, JJ; Patsalos, PN; Ratnaraj, N; Sielski, M1
Gopal, K; Gross, GW; Lukas, TJ; Moore, EJ; Wu, C1
Goel, A; Goel, R; Kumar, Y1
Czuczwar, SJ; Luszczki, JJ; Nieoczym, D; Socała, K; Wlaź, P1
Bogo, MR; Bonan, CD; Nery, LR; Piato, AL; Schaefer, IC; Siebel, AM1
Banote, RK; Chatti, K; Chennubhotla, KS; Koutarapu, S; Kulkarni, P1
Jenita, JL; Lavanya, Y; Priyadarshini, SR; Ramasamy, M; Wilson, B1
Essawy, SS; Ewais, MM; Mohammed, AS; Tawfik, MK1
Ahmad, N; Akbar, S; Ali, G; Fawad, K; Karim, N; Mahmood, W; Shahid, M; Subhan, F1
Elhabak, M; Salama, AAA; Salama, AH1
Ali, G; Ayaz, M; Bungau, S; Hassan, SSU; Khan, FA; Khan, Y; Mosa, OF; Nawaz, A; Rahman, K1

Other Studies

21 other study(ies) available for pentylenetetrazole and gabapentin

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Anticonvulsant action of gabapentin during postnatal development in rats.
    Epilepsia, 1997, Volume: 38, Issue:8

    Topics: Acetates; Amines; Animals; Anticonvulsants; Behavior, Animal; Brain; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Gabapentin; gamma-Aminobutyric Acid; Male; Pentylenetetrazole; Rats; Rats, Wistar; Seizures

1997
Experimental conditions for the continuous subcutaneous infusion of four central analgesics in rats.
    Pharmacology, biochemistry, and behavior, 2002, Volume: 72, Issue:4

    Topics: Acetates; Amines; Analgesics; Anesthetics, Dissociative; Animals; Anticonvulsants; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Chronic Disease; Convulsants; Cyclohexanecarboxylic Acids; Drug Stability; Gabapentin; gamma-Aminobutyric Acid; Hypothermia; Imipramine; Infusion Pumps, Implantable; Ketamine; Male; Morphine; Pain; Pain Measurement; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Solubility; Tetrabenazine

2002
Isobolographic profile of interactions between tiagabine and gabapentin: a preclinical study.
    Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 369, Issue:4

    Topics: Amines; Animals; Anticonvulsants; Convulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Nipecotic Acids; Pentylenetetrazole; Seizures; Tiagabine

2004
Posttraining administration of pentylenetetrazol dissociates gabapentin effects on memory consolidation from that on memory retrieval process in mice.
    Neuroscience letters, 2004, Sep-23, Volume: 368, Issue:2

    Topics: Amines; Animals; Anticonvulsants; Avoidance Learning; Behavior, Animal; Convulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Male; Memory; Mice; Mice, Inbred Strains; Naltrexone; Narcotic Antagonists; Pentylenetetrazole; Reaction Time; Retention, Psychology; Time Factors

2004
The novel GABA adamantane derivative (AdGABA): design, synthesis, and activity relationship with gabapentin.
    Bioorganic & medicinal chemistry, 2005, Apr-15, Volume: 13, Issue:8

    Topics: Acetates; Adamantane; Amines; Analgesics; Animals; Anticonvulsants; Calcium Channels; Cell Line; Cell Membrane; Cyclohexanecarboxylic Acids; Drug Design; Gabapentin; gamma-Aminobutyric Acid; Humans; Mice; Models, Animal; Molecular Structure; Pentylenetetrazole; Rats; Semicarbazides; Structure-Activity Relationship

2005
Isobolographic characterisation of interactions among selected newer antiepileptic drugs in the mouse pentylenetetrazole-induced seizure model.
    Naunyn-Schmiedeberg's archives of pharmacology, 2005, Volume: 372, Issue:1

    Topics: Amines; Animals; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Motor Activity; Nipecotic Acids; Oxcarbazepine; Pentylenetetrazole; Seizures; Tiagabine

2005
Tramadol-induced seizurogenic effect: a possible role of opioid-dependent gamma-aminobutyric acid inhibitory pathway.
    Basic & clinical pharmacology & toxicology, 2008, Volume: 103, Issue:3

    Topics: Amines; Analgesics, Opioid; Animals; Cyclohexanecarboxylic Acids; GABA Agents; Gabapentin; gamma-Aminobutyric Acid; Mice; Mice, Inbred Strains; Naloxone; Narcotic Antagonists; Pentylenetetrazole; Receptors, GABA; Receptors, Opioid; Seizures; Tramadol

2008
Isobolographic and behavioral characterizations of interactions between vigabatrin and gabapentin in two experimental models of epilepsy.
    European journal of pharmacology, 2008, Oct-24, Volume: 595, Issue:1-3

    Topics: Amines; Animals; Anticonvulsants; Behavior, Animal; Brain; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Muscle Strength; Pentylenetetrazole; Psychomotor Performance; Seizures; Vigabatrin

2008
Pharmacodynamic and pharmacokinetic interaction profiles of levetiracetam in combination with gabapentin, tiagabine and vigabatrin in the mouse pentylenetetrazole-induced seizure model: an isobolographic analysis.
    European journal of pharmacology, 2009, Mar-01, Volume: 605, Issue:1-3

    Topics: Amines; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Interactions; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Levetiracetam; Male; Mice; Nipecotic Acids; Pentylenetetrazole; Piracetam; Seizures; Tiagabine; Tissue Distribution; Vigabatrin

2009
An in vitro model for testing drugs to treat tinnitus.
    European journal of pharmacology, 2011, Sep-30, Volume: 667, Issue:1-3

    Topics: Amines; Animals; Antioxidants; Calcium Channel Blockers; Carnitine; Convulsants; Cyclohexanecarboxylic Acids; Drug Evaluation, Preclinical; Gabapentin; gamma-Aminobutyric Acid; Indoles; Mice; Neurons; Pentylenetetrazole; Potassium Channel Blockers; Pregabalin; Pyridines; Tinnitus

2011
Influence of carvedilol on anticonvulsant effect of gabapentin.
    Acta neurologica Belgica, 2011, Volume: 111, Issue:4

    Topics: Amines; Analysis of Variance; Animals; Anticonvulsants; Brain; Carbazoles; Carvedilol; Convulsants; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Electroshock; Exploratory Behavior; Gabapentin; gamma-Aminobutyric Acid; Glutathione; Lipid Peroxidation; Male; Malondialdehyde; Memory; Mice; Motor Activity; Pentylenetetrazole; Propanolamines; Rotarod Performance Test; Seizures; Vasodilator Agents

2011
Sildenafil influences the anticonvulsant activity of vigabatrin and gabapentin in the timed pentylenetetrazole infusion test in mice.
    Progress in neuro-psychopharmacology & biological psychiatry, 2012, Oct-01, Volume: 39, Issue:1

    Topics: Amines; Animals; Anticonvulsants; Avoidance Learning; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Hand Strength; Male; Mice; Motor Skills; Pentylenetetrazole; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Seizures; Sildenafil Citrate; Sulfones; Vigabatrin

2012
Antiepileptic drugs prevent changes in adenosine deamination during acute seizure episodes in adult zebrafish.
    Pharmacology, biochemistry, and behavior, 2013, Volume: 104

    Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase; Amines; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Disease Models, Animal; Female; Gabapentin; gamma-Aminobutyric Acid; Gene Expression; Male; Pentylenetetrazole; Phenytoin; Seizures; Valproic Acid; Zebrafish

2013
Oral gabapentin suppresses pentylenetetrazole-induced seizure-like behavior and cephalic field potential in adult zebrafish.
    Epilepsy & behavior : E&B, 2013, Volume: 27, Issue:1

    Topics: Action Potentials; Administration, Oral; Amines; Analysis of Variance; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Locomotion; Male; Pentylenetetrazole; Seizures; Time Factors; Zebrafish

2013
Albumin nanoparticles for the delivery of gabapentin: preparation, characterization and pharmacodynamic studies.
    International journal of pharmaceutics, 2014, Oct-01, Volume: 473, Issue:1-2

    Topics: Amines; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Carriers; Drug Compounding; Electroshock; Gabapentin; gamma-Aminobutyric Acid; Male; Nanoparticles; Pentylenetetrazole; Polysorbates; Rats, Wistar; Seizures; Serum Albumin, Bovine

2014
Effects of intravenous human umbilical cord blood mesenchymal stem cell therapy versus gabapentin in pentylenetetrazole-induced chronic epilepsy in rats.
    Pharmacology, 2014, Volume: 94, Issue:1-2

    Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intraperitoneal; Injections, Intravenous; Mesenchymal Stem Cell Transplantation; Oxidative Stress; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Umbilical Cord

2014
6-Methoxyflavanone attenuates mechanical allodynia and vulvodynia in the streptozotocin-induced diabetic neuropathic pain.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 84

    Topics: Amines; Animals; Computer Simulation; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Female; Flavanones; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Models, Molecular; Naloxone; Neuralgia; Nociception; Pentylenetetrazole; Rats, Sprague-Dawley; Receptors, GABA; Streptozocin; Toxicity Tests, Acute; Vulvodynia

2016
Single step nanospray drying preparation technique of gabapentin-loaded nanoparticles-mediated brain delivery for effective treatment of PTZ-induced seizures.
    International journal of pharmaceutics, 2021, Jun-01, Volume: 602

    Topics: Animals; Brain; Chitosan; Drug Carriers; Gabapentin; Nanoparticles; Particle Size; Pentylenetetrazole; Rats; Seizures

2021
Efficacy of 2-Hydroxyflavanone in Rodent Models of Pain and Inflammation: Involvement of Opioidergic and GABAergic Anti-Nociceptive Mechanisms.
    Molecules (Basel, Switzerland), 2022, Aug-25, Volume: 27, Issue:17

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Cisplatin; Disease Models, Animal; Edema; Flavanones; Gabapentin; Hyperalgesia; Inflammation; Naloxone; Neuralgia; Pentylenetetrazole; Rodentia

2022