Page last updated: 2024-08-17

pentylenetetrazole and flurothyl

pentylenetetrazole has been researched along with flurothyl in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199012 (50.00)18.7374
1990's3 (12.50)18.2507
2000's5 (20.83)29.6817
2010's3 (12.50)24.3611
2020's1 (4.17)2.80

Authors

AuthorsStudies
Duffy, TE; Howse, DC; Plum, F2
Adler, MW; Braverman, S; Geller, EB; Keinath, SH; Lin, CH1
Beresford, HR; Doba, N; Reis, DJ1
Maher, TJ; Pinto, JM1
Alpern, HP; McIntyre, TD1
Albala, BJ; Moshé, SL; Okada, R; Ono, K1
Abrams, R; Fink, M1
Browning, RA; Simonton, RL; Turner, FJ1
Cammer, W; Moshé, SL; Velísek, L; Xu, SG1
Firkusny, IR; Jensen, FE; Mower, GD1
Ben-Ari, Y; Chevassus-Au-Louis, N; Gairsa, JL; Holmes, GL1
Cole, TB; Palmiter, RD; Robbins, CA; Schwartzkroin, PA; Wenzel, HJ1
Geula, C; Holmes, GL; Schachter, SC; Schomer, DL; Silveira, DC1
Hohmann, JG; Miller, NS; Palmiter, RD; Pyati, U; Rust, NC; Szot, P; Weinshenker, D; White, SS1
CHATRIAN, GE; PETERSEN, MC1
ADLER, MW1
BUTLER, HR; MANAX, SJ; STAVRAKY, GW1
Ahern, TH; Eagles, DA; Javors, MA; Liles, LC; Martillotti, J; Mitchell, HA; Weinshenker, D1
Bo, T; Chen, Y; Li, YF; Mao, DA; Zhu, XH1
Paz, C; Retana-Márquez, S; Rubio, C; Rubio-Osornio, M; Verónica Custodio, ML1
Cooper, K; Fink, M1
Borges, K; Carrasco-Pozo, C; Tan, KN1
Bell, TA; Dalton, KA; Gu, B; Hock, P; Miller, DR; Pan, Y; Pardo-Manuel de Villena, F; Philpot, BD; Shaw, GD; Shorter, JR; Williams, LH1

Reviews

2 review(s) available for pentylenetetrazole and flurothyl

ArticleYear
In vivo experimental models of epilepsy.
    Central nervous system agents in medicinal chemistry, 2010, Dec-01, Volume: 10, Issue:4

    Topics: Aluminum Hydroxide; Animals; Bicuculline; Cobalt; Convulsants; Disease Models, Animal; Electroshock; Epilepsy; Epilepsy, Reflex; Flurothyl; gamma-Aminobutyric Acid; Humans; Kainic Acid; Kindling, Neurologic; Muscarinic Agonists; Papio; Penicillins; Pentylenetetrazole; Pilocarpine; Tetanus Toxin; Zinc Compounds

2010
The chemical induction of seizures in psychiatric therapy: were flurothyl (indoklon) and pentylenetetrazol (metrazol) abandoned prematurely?
    Journal of clinical psychopharmacology, 2014, Volume: 34, Issue:5

    Topics: Animals; Electroconvulsive Therapy; Flurothyl; Humans; Memory Disorders; Mental Disorders; Pentylenetetrazole; Seizures

2014

Other Studies

22 other study(ies) available for pentylenetetrazole and flurothyl

ArticleYear
Cerebral energy metabolism during experimental status epilepticus.
    Journal of neurochemistry, 1975, Volume: 24, Issue:5

    Topics: Adenine Nucleotides; Animals; Blood Pressure; Brain; Creatine Kinase; Electroencephalography; Electroshock; Energy Metabolism; Flurothyl; Glucose; Glycogen; Hydrogen-Ion Concentration; L-Lactate Dehydrogenase; Lactates; Male; Mice; NAD; Oxidation-Reduction; Pentylenetetrazole; Phosphocreatine; Rats; Seizures

1975
Anticonvulsant action of acute morphine administration in rats.
    The Journal of pharmacology and experimental therapeutics, 1976, Volume: 198, Issue:3

    Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Flurothyl; Male; Morphine; Pentylenetetrazole; Rats

1976
Changes in regional blood flow and cardiodynamics associated with electrically and chemically induced epilepsy in cat.
    Brain research, 1975, Jun-06, Volume: 90, Issue:1

    Topics: Adrenalectomy; Animals; Atropine; Blood Pressure; Cardiac Output; Cats; Electric Stimulation; Electroencephalography; Epilepsy; Flurothyl; Heart Rate; Hemodynamics; Hydroxydopamines; Neurosurgery; Paresis; Pentylenetetrazole; Phentolamine; Regional Blood Flow; Sympathectomy; Vascular Resistance

1975
Administration of aspartame potentiates pentylenetetrazole- and fluorothyl-induced seizures in mice.
    Neuropharmacology, 1988, Volume: 27, Issue:1

    Topics: Animals; Aspartame; Dipeptides; Dose-Response Relationship, Drug; Drug Synergism; Flurothyl; Male; Mice; Pentylenetetrazole; Phenylalanine; Seizures; Tyrosine

1988
Differential convulsive susceptibility of high-activity and low-activity selected mice in response to GABA antagonists.
    Pharmacology, biochemistry, and behavior, 1987, Volume: 26, Issue:1

    Topics: Animals; Behavior, Animal; Bicuculline; Female; Flurothyl; GABA Antagonists; Male; Mice; Pentylenetetrazole; Seizures; Species Specificity

1987
Unidirectional interaction between flurothyl seizures and amygdala kindling.
    Brain research, 1985, Sep-30, Volume: 344, Issue:1

    Topics: Amygdala; Animals; Disease Susceptibility; Electric Stimulation; Flurothyl; Kindling, Neurologic; Male; Pentylenetetrazole; Rats; Seizures

1985
Metabolic effects of seizures.
    Research publications - Association for Research in Nervous and Mental Disease, 1974, Volume: 53

    Topics: Acidosis; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Bicarbonates; Blood Flow Velocity; Brain; Carbon Dioxide; Cats; Cerebrovascular Circulation; Dogs; Electric Stimulation; Energy Metabolism; Epilepsy; Flurothyl; Hydrogen-Ion Concentration; Lactates; Mice; NAD; Oxygen; Oxygen Consumption; Pentylenetetrazole; Phosphocreatine; Pyruvates; Rats; Seizures

1974
Answers to questions frequently asked about ECT.
    Seminars in psychiatry, 1972, Volume: 4, Issue:1

    Topics: Age Factors; Anesthesia, Intravenous; Brain Damage, Chronic; Brain Neoplasms; Depression; Electroconvulsive Therapy; Flurothyl; Forensic Psychiatry; Functional Laterality; Humans; Informed Consent; Intracranial Aneurysm; Lithium; Methohexital; Monoamine Oxidase Inhibitors; Myocardial Infarction; New York; Paranoid Disorders; Pentylenetetrazole; Premedication; Reserpine; Schizophrenia; Succinylcholine

1972
Antagonism of experimentally induced tonic seizures following a lesion in the midbrain tegmentum.
    Epilepsia, 1981, Volume: 22, Issue:5

    Topics: Animals; Disease Models, Animal; Electroshock; Flurothyl; Hindlimb; Male; Muscles; Pentylenetetrazole; Rats; Seizures; Tegmentum Mesencephali

1981
Reduced susceptibility to seizures in carbonic anhydrase II deficient mutant mice.
    Epilepsy research, 1993, Volume: 14, Issue:2

    Topics: Acoustic Stimulation; Animals; Carbonic Anhydrases; Disease Susceptibility; Epilepsy, Tonic-Clonic; Flurothyl; Mice; Mice, Mutant Strains; Pentylenetetrazole; Reaction Time; Seizures

1993
Differences in c-fos immunoreactivity due to age and mode of seizure induction.
    Brain research. Molecular brain research, 1993, Volume: 17, Issue:3-4

    Topics: Aging; Animals; Flurothyl; Hypoxia; Immunohistochemistry; Pentylenetetrazole; Proto-Oncogene Proteins c-fos; Rats; Seizures

1993
Consequences of neonatal seizures in the rat: morphological and behavioral effects.
    Annals of neurology, 1998, Volume: 44, Issue:6

    Topics: Animals; Animals, Newborn; Behavior, Animal; Brain; Bromodeoxyuridine; Cell Count; Convulsants; Differential Threshold; Electroencephalography; Electrophysiology; Flurothyl; Maze Learning; Motor Activity; Pentylenetetrazole; Rats; Rats, Wistar; Recurrence; Seizures; Swimming

1998
Seizures and neuronal damage in mice lacking vesicular zinc.
    Epilepsy research, 2000, Volume: 39, Issue:2

    Topics: Animals; Bicuculline; Carrier Proteins; Cation Transport Proteins; Convulsants; Dose-Response Relationship, Drug; Electroencephalography; Flurothyl; Genetic Predisposition to Disease; Kainic Acid; Membrane Proteins; Membrane Transport Proteins; Metallothionein 3; Mice; Mice, Knockout; Nerve Tissue Proteins; Neurons; Pentylenetetrazole; Seizures; Synapses; Synaptic Vesicles; Zinc

2000
Increased susceptibility to generalized seizures after immunolesions of the basal forebrain cholinergic neurons in rats.
    Brain research, 2000, Sep-29, Volume: 878, Issue:1-2

    Topics: Acetylcholinesterase; Animals; Convulsants; Denervation; Disease Susceptibility; Epilepsy, Generalized; Flurothyl; Immunotoxins; Male; N-Glycosyl Hydrolases; Neurons; Pentylenetetrazole; Plant Proteins; Prosencephalon; Rats; Rats, Sprague-Dawley; Ribosome Inactivating Proteins, Type 1; Saporins

2000
Genetic comparison of seizure control by norepinephrine and neuropeptide Y.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Oct-01, Volume: 21, Issue:19

    Topics: Animals; Dopamine beta-Hydroxylase; Exercise Test; Flurothyl; Genetic Predisposition to Disease; Handling, Psychological; In Situ Hybridization; Kainic Acid; Male; Mice; Mice, Knockout; Neuropeptide Y; Norepinephrine; Pentylenetetrazole; Phenotype; Seizures

2001
The convulsive patterns provoked by indoklon, metrazol and electroshock: some depth electrographic observations in human patients.
    Electroencephalography and clinical neurophysiology, 1960, Volume: 12

    Topics: Electroencephalography; Electroshock; Flurothyl; Humans; Pentylenetetrazole; Seizures

1960
INCREASED SENSITIVITY TO PENTYLENETETRAZOL AND FLUROTHYL FOLLOWING CORTICAL ABLATIONS IN RATS.
    The Journal of pharmacology and experimental therapeutics, 1965, Volume: 148

    Topics: Central Nervous System Stimulants; Cerebral Cortex; Cerebral Decortication; Flurothyl; Pentylenetetrazole; Pharmacology; Research; Seizures; Toxicology

1965
HEXAFLUORODIETHYL ETHER (INDOKLON) CONVULSIONS IN CORPUS-CALLOTOMIZED WHITE RATS.
    Canadian journal of physiology and pharmacology, 1964, Volume: 42

    Topics: Brain; Corpus Callosum; Drug Tolerance; Ether; Ethers; Flurothyl; Hypoxia, Brain; Pentylenetetrazole; Rats; Research; Seizures; Toxicology

1964
The effects of chronic norepinephrine transporter inactivation on seizure susceptibility in mice.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2006, Volume: 31, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Disease Models, Animal; Dopamine beta-Hydroxylase; Drug Administration Schedule; Electroshock; Flurothyl; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Norepinephrine Plasma Membrane Transport Proteins; Pentylenetetrazole; Reaction Time; Reboxetine; Seizures

2006
[Long-term effects of recurrent seizures in neonate period on gamma-aminobutyric acid A receptor alpha1 and beta2 subunits expression in adult brain: experiment with rats].
    Zhonghua yi xue za zhi, 2007, Jan-23, Volume: 87, Issue:4

    Topics: Animals; Animals, Newborn; Brain; Cerebral Cortex; Disease Models, Animal; Flurothyl; Hippocampus; Immunohistochemistry; Maze Learning; Pentylenetetrazole; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Seizures; Time Factors

2007
Sulforaphane is anticonvulsant and improves mitochondrial function.
    Journal of neurochemistry, 2015, Volume: 135, Issue:5

    Topics: Animals; Anticonvulsants; Convulsants; Disease Models, Animal; Electron Transport Complex I; Electroshock; Epilepsy; Flurothyl; Hippocampus; Isothiocyanates; Lipid Peroxidation; Male; Malondialdehyde; Mice; Mitochondria; Nerve Degeneration; Oxidative Stress; Pentylenetetrazole; Pilocarpine; Sulfoxides; Superoxide Dismutase

2015
Collaborative Cross mice reveal extreme epilepsy phenotypes and genetic loci for seizure susceptibility.
    Epilepsia, 2020, Volume: 61, Issue:9

    Topics: Animals; Chromosome Mapping; Collaborative Cross Mice; Convulsants; Disease Models, Animal; Epilepsy; Excitatory Amino Acid Agonists; Flurothyl; Gene Expression; Gene Expression Profiling; Genetic Predisposition to Disease; Genotype; Hippocampus; Kainic Acid; Mice; Mice, Inbred Strains; Pentylenetetrazole; Phenotype; Quantitative Trait Loci; Seizures; Sudden Unexpected Death in Epilepsy; Whole Genome Sequencing

2020