Page last updated: 2024-08-17

pentylenetetrazole and chlorine

pentylenetetrazole has been researched along with chlorine in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199019 (50.00)18.7374
1990's10 (26.32)18.2507
2000's6 (15.79)29.6817
2010's3 (7.89)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pellmar, TC; Wilson, WA1
Corda, MG; Giorgi, O; Orlandi, M1
Gettins, D; Goldsack, N; Ibegbuna, V; Stanford, SC1
Kuhlmann, D; Madeja, M; Musshoff, U; Speckmann, EJ1
Hasegawa, T; Hashimoto, H; Nakajima, T; Nakao, J; Noto, T1
Hill, JL; Insel, TR; Mayor, RB1
Fishman, BE; Gianutsos, G1
Schneider, HH; Stephens, DN; Weidmann, R; Zimmermann, L1
Chang, YF; Gao, XM1
Speckmann, EJ; Walden, J; Witte, OW1
Schmidt, J1
Prichard, JW2
Funcke, AB; Gootjes, J; Nauta, WT1
Erdélyi, I; Institoris, E; Lányi, K; Lovász, M; Tardos, L1
Gross, GJ; Woodbury, DM1
Straw, RN1
Chen, CF; Chow, SY; Engstrom, FL; Kemp, JW; White, HS; Woodbury, DM1
Koff, JM; Miller, LG1
Pomés, A; Rodríguez-Farré, E; Suñol, C1
Bingmann, D; Bonnet, U1
Belonga, KL; Carter, DB; Im, HK; Im, WB; Jacobsen, EJ; Petke, JD; Sethy, VH; Stelzer, LS; Tang, AH; TenBrink, RE; VonVoigtlander, PF1
Klöcker, N; Madeja, M; Musshoff, U; Speckmann, EJ1
Sharma, V; Singh, R1
MAGISTRETTI, MJ; SETNIKAR, I1
Abrosimov, IY; Andreev, AA; Belykh, NP; Kalinina, MS; Karpova, MN; Kuzina, OS; Rebrov, IG1
Bassi, GS; Coimbra, NC; de Carvalho, AD; de Freitas, RL; de Oliveira, RC; Elias-Filho, DH; Felippotti, TT1
Frye, CA; Rhodes, ME1
Andreev, AA; Kalinina, MV; Karpova, MN; Klishina, NY; Kuzina, OS; Kuznetsova, LV; Rebrov, IG1
Andreev, AA; Kalinina, MV; Karpova, MN; Klishina, NY; Kusnetzova, LV; Rebrov, IG2
Cheong, JH; dela Peña, IC; Ko, KH; Lee, YS; Ryu, JH; Shin, CY; Son, KH; Yoon, SY1
Demir, G; Oztaş, B; Seker, FB; Yalçın, IE; Yorulmaz, H1
Bahramnejad, E; Dehpour, AR; Faghir-Ghanesefat, H; Hassanipour, M; Pourshadi, N; Rahimi, N; Yarmohammadi, F1
Buzello, W; Jantzen, K; Scholler, KL1
Pfeifer, AK1
De Angelis, L; Traversa, U; Vertua, R1
Airoldi, L; Garattini, S; Guaitani, A; Marcucci, F; Mussini, E1

Other Studies

38 other study(ies) available for pentylenetetrazole and chlorine

ArticleYear
Synaptic mechanism of pentylenetetrazole: selectivity for chloride conductance.
    Science (New York, N.Y.), 1977, Aug-26, Volume: 197, Issue:4306

    Topics: Acetylcholine; Animals; Chlorides; Dopamine; Electric Conductivity; gamma-Aminobutyric Acid; Membrane Potentials; Mollusca; Pentylenetetrazole; Potassium; Serotonin; Sodium; Synaptic Membranes

1977
Decrease in GABAA receptor function induced by pentylenetetrazol kindling in the rat: role of N-methyl-D-aspartate (NMDA) receptors.
    Advances in biochemical psychopharmacology, 1992, Volume: 47

    Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chlorides; Dizocilpine Maleate; Down-Regulation; Isoniazid; Kindling, Neurologic; Male; Pentylenetetrazole; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate

1992
Effects of GABAA receptor ligands on noradrenaline concentration and beta-adrenoceptor binding in mouse cerebral cortex.
    Psychopharmacology, 1990, Volume: 102, Issue:3

    Topics: Alkaloids; Animals; Azepines; Cerebral Cortex; Chlorides; Heterocyclic Compounds, 4 or More Rings; Heterocyclic Compounds, Bridged-Ring; Ion Channels; Kinetics; Lactones; Male; Mice; Neuromuscular Depolarizing Agents; Norepinephrine; Pentylenetetrazole; Picrotoxin; Piperidines; Receptors, Adrenergic, beta; Receptors, GABA-A; Yohimbine

1990
Membrane currents elicited by the epileptogenic drug pentylenetetrazole in the native oocyte of Xenopus laevis.
    Brain research, 1991, Jul-05, Volume: 553, Issue:1

    Topics: Animals; Chlorides; Electrodes; Ion Channels; Membrane Potentials; Oocytes; Pentylenetetrazole; Potassium; Potassium Channels; Xenopus laevis

1991
Formation of GABOB from 2-hydroxyputrescine and its anticonvulsant effect.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 40, Issue:2

    Topics: 4-Aminobutyrate Transaminase; Amine Oxidase (Copper-Containing); Amino Acids; Animals; Anticonvulsants; Brain Chemistry; Cell Membrane; Chlorides; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Injections, Intraperitoneal; Injections, Intraventricular; Male; Pentylenetetrazole; Putrescine; Rats; Rats, Inbred Strains; Seizures

1991
Rat pup ultrasonic isolation calls: possible mediation by the benzodiazepine receptor complex.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:5

    Topics: Animals; Benzodiazepinones; Chlorides; Diazepam; Flumazenil; Ion Channels; Pentylenetetrazole; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sex Factors; Temperature; Vocalization, Animal

1986
CNS biochemical and pharmacological effects of the isomers of hexachlorocyclohexane (lindane) in the mouse.
    Toxicology and applied pharmacology, 1988, Mar-30, Volume: 93, Issue:1

    Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Drug Synergism; Hexachlorocyclohexane; Ion Channels; Male; Mice; Motor Activity; Pentylenetetrazole; Picrotoxin; Receptors, GABA-A; Seizures

1988
Decreased sensitivity to benzodiazepine receptor agonists and increased sensitivity to inverse agonists following chronic treatments: evidence for separate mechanisms.
    Advances in biochemical psychopharmacology, 1988, Volume: 45

    Topics: Animals; Anti-Anxiety Agents; Appetite Depressants; Benzodiazepines; Carbolines; Chlorides; Diazepam; Drug Interactions; Drug Tolerance; Exploratory Behavior; Ion Channels; Kindling, Neurologic; Locomotion; Lorazepam; Mice; Muscimol; Pentylenetetrazole; Rats; Receptors, GABA-A

1988
Enhancement of benzodiazepine receptor binding by L-lysine is chloride-dependent and due to increase in binding affinity.
    European journal of pharmacology, 1989, Dec-07, Volume: 173, Issue:2-3

    Topics: Animals; Cattle; Chlorides; Flunitrazepam; In Vitro Techniques; Kinetics; Lysine; Pentylenetetrazole; Picrotoxin; Receptors, GABA-A; Sesterterpenes; Synaptic Membranes

1989
Membrane currents induced by pentylenetetrazol in identified neurons of Helix pomatia.
    Brain research, 1988, Nov-15, Volume: 473, Issue:2

    Topics: Animals; Calcium; Calcium Channels; Chlorides; Electric Conductivity; Helix, Snails; In Vitro Techniques; Membrane Potentials; Neurons; Pentylenetetrazole; Potassium; Quaternary Ammonium Compounds; Sodium

1988
Lithium suppresses seizure susceptibility in pentylenetetrazol-kindled rats.
    Biomedica biochimica acta, 1986, Volume: 45, Issue:9

    Topics: Animals; Chlorides; Disease Susceptibility; Female; Kindling, Neurologic; Lithium; Lithium Chloride; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures

1986
Effect of pentylenetetrazol on the leech retzius cell.
    Experimental neurology, 1971, Volume: 32, Issue:2

    Topics: Action Potentials; Animals; Cell Membrane; Cell Membrane Permeability; Chlorides; Electrolytes; Leeches; Magnesium Sulfate; Membrane Potentials; Neurons; Osmosis; Ouabain; Pentylenetetrazole; Potassium; Synapses; Synaptic Transmission

1971
Experiments in the 5H-dibenzo(a,d)cycloheptene series. IV. Synthesis and pharmacology of some 10-mono and 5,10-disubstituted 5H-dibenzo(a,d)cycloheptenes.
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:12

    Topics: Acetylcholine; Alkenes; Animals; Barium; Central Nervous System; Chlorides; Cycloheptanes; Diphenhydramine; Diuretics; Electroshock; Esters; Ethers; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Intestines; Male; Mice; Parasympatholytics; Parasympathomimetics; Pentylenetetrazole; Pyrrolidines; Rats; Tremorine

1969
[Piperazine derivatives. 3. Effect of carbonyl- and hydroxy-derivatives (1)].
    Die Pharmazie, 1970, Volume: 25, Issue:3

    Topics: Analgesics; Anesthesia; Animals; Antihypertensive Agents; Barium; Blood Pressure; Body Temperature; Carbachol; Chlorides; Coronary Vessels; Depression, Chemical; Drug Synergism; Electroshock; Histamine H1 Antagonists; Mice; Muscle, Smooth; Nicotine; Parasympatholytics; Pentylenetetrazole; Piperazines; Rats; Time Factors; Urethane; Vasodilator Agents

1970
Effects of pentylenetetrazol on ion transport in the isolated toad bladder.
    The Journal of pharmacology and experimental therapeutics, 1972, Volume: 181, Issue:2

    Topics: Amphotericin B; Animals; Biological Transport; Bufo marinus; Cell Membrane Permeability; Chlorides; Drug Interactions; In Vitro Techniques; Membrane Potentials; Osmolar Concentration; Pentylenetetrazole; Potassium; Potassium Isotopes; Sodium; Sodium Isotopes; Structure-Activity Relationship; Trimethadione; Urinary Bladder; Vasopressins

1972
Pentylenetetrazol-induced increase in chloride permeability of leech neurons.
    Brain research, 1971, Apr-02, Volume: 27, Issue:2

    Topics: Animals; Cell Membrane Permeability; Chlorides; Electric Stimulation; Ganglia; Leeches; Membrane Potentials; Neurons; Pentylenetetrazole

1971
The effect of selected neuromuscular blocking agents on the duration of pentylenetetrazol-induced sezures.
    Archives internationales de pharmacodynamie et de therapie, 1968, Volume: 175, Issue:2

    Topics: Animals; Bromides; Cats; Chlorides; Decamethonium Compounds; Female; Gallamine Triethiodide; Male; Pentylenetetrazole; Seizures; Succinylcholine; Time Factors

1968
Ionic and acid-base regulation of neurons and glia during seizures.
    Annals of neurology, 1984, Volume: 16 Suppl

    Topics: Acid-Base Equilibrium; Adenosine Triphosphatases; Animals; Anion Transport Proteins; Bicarbonates; Carbonic Anhydrases; Cerebral Cortex; Chlorides; Cobalt; Epilepsy; Extracellular Space; Humans; Ion Channels; Neuroglia; Neurons; Pentylenetetrazole; Seizures; Sodium-Potassium-Exchanging ATPase

1984
Prenatal lorazepam exposure: 4. Persistent alterations in pentylenetetrazole-induced seizure threshold and GABA-dependent chloride uptake after prenatal lorazepam exposure.
    Pharmacology, biochemistry, and behavior, 1995, Volume: 51, Issue:4

    Topics: Animals; Brain Chemistry; Chlorides; Chlorine; Female; gamma-Aminobutyric Acid; Lorazepam; Mice; Muscimol; Pentylenetetrazole; Pregnancy; Prenatal Exposure Delayed Effects; Radioisotopes; Seizures

1995
Disruption of GABA-dependent chloride flux by cyclodienes and hexachlorocyclohexanes in primary cultures of cortical neurons.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:3

    Topics: Animals; Calcium; Cells, Cultured; Cerebral Cortex; Chlorides; Endosulfan; Female; gamma-Aminobutyric Acid; Insecticides; Mice; Pentylenetetrazole; Picrotoxin; Pregnancy; Receptors, GABA-A; Sesterterpenes

1994
GABA-responses of CA3 neurones at epileptogenic threshold concentrations of convulsants.
    Neuroreport, 1993, Volume: 4, Issue:6

    Topics: Action Potentials; Animals; Bicarbonates; Bicuculline; Caffeine; Chlorides; Convulsants; Epilepsy; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Membrane Potentials; Neurons; Penicillins; Pentylenetetrazole; Synapses

1993
High-affinity partial agonist imidazo[1,5-a]quinoxaline amides, carbamates, and ureas at the gamma-aminobutyric acid A/benzodiazepine receptor complex.
    Journal of medicinal chemistry, 1996, Jan-05, Volume: 39, Issue:1

    Topics: Animals; Anxiety; Benzodiazepines; Binding, Competitive; Brain; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Flunitrazepam; GABA Agonists; GABA Antagonists; Molecular Conformation; Molecular Structure; Oxadiazoles; Pentylenetetrazole; Quinoxalines; Rats; Receptors, GABA-A

1996
Activation of ATP-sensitive potassium channels in follicle-enclosed xenopus oocytes by the epileptogenic agent pentylenetetrazol.
    Pflugers Archiv : European journal of physiology, 1996, Volume: 431, Issue:5

    Topics: Adenosine Triphosphate; Animals; Cell Membrane; Cesium; Chlorides; Convulsants; Gap Junctions; Membrane Potentials; Oocytes; Pentylenetetrazole; Potassium Channel Blockers; Potassium Channels; Tetraethylammonium; Tetraethylammonium Compounds; Xenopus

1996
Electroencephalographic study of the effect of neurotoxin DSP-4 in iron model of chronic focal epilepsy.
    Indian journal of experimental biology, 1999, Volume: 37, Issue:5

    Topics: Animals; Benzylamines; Cerebral Cortex; Chlorides; Electroencephalography; Epilepsy; Ferric Compounds; Locus Coeruleus; Male; Neurotoxins; Pentylenetetrazole; Pilocarpine; Rats; Rats, Wistar

1999
CARDIAC EFFECTS OF DIMEFLINE COMPARED WITH THOSE OF OTHER CENTRAL NERVOUS SYSTEM STIMULANTS.
    Archives internationales de pharmacodynamie et de therapie, 1964, Sep-01, Volume: 151

    Topics: Aminobutyrates; Bemegride; Benzene; Calcium; Central Nervous System Stimulants; Chlorides; Coronary Vessels; Electrocardiography; Epinephrine; Flavones; Flavonoids; Guinea Pigs; Heart; Nikethamide; Pentylenetetrazole; Pharmacology; Picrotoxin; Research; Seizures; Strychnine; Toxicology; Ventricular Fibrillation

1964
Effect of single injection of pentylenetetrazole in a subconvulsive dose on Cl- conductance of the GABAA-receptor complex.
    Bulletin of experimental biology and medicine, 2004, Volume: 137, Issue:1

    Topics: Animals; Cerebral Cortex; Chloride Channels; Chlorides; Convulsants; Electric Conductivity; Epilepsy; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Injections; Male; Muscimol; Pentylenetetrazole; Rats; Rats, Wistar; Synaptosomes

2004
Role of muscarinic and nicotinic cholinergic receptors in an experimental model of epilepsy-induced analgesia.
    Pharmacology, biochemistry, and behavior, 2004, Volume: 79, Issue:2

    Topics: Animals; Atropine; Chlorides; Convulsants; Epilepsy; GABA Antagonists; Male; Mecamylamine; Muscarinic Antagonists; Nicotinic Antagonists; Nociceptors; Pain Measurement; Pentylenetetrazole; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Muscarinic; Receptors, Nicotinic

2004
Actions at GABA(A) receptors in the hippocampus may mediate some antiseizure effects of progestins.
    Epilepsy & behavior : E&B, 2005, Volume: 6, Issue:3

    Topics: Analysis of Variance; Animals; Anticonvulsants; Behavior, Animal; Bicuculline; Chlorides; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Female; gamma-Aminobutyric Acid; Hippocampus; Isotopes; Ovariectomy; Pentylenetetrazole; Progestins; Rats; Rats, Long-Evans; Reaction Time; Receptors, GABA-A; Seizures; Tissue Distribution

2005
Cl- conduction of GABA(A) receptor complex on synaptic membranes in rat cortex at the early stage of chronic cerebral epileptization.
    Bulletin of experimental biology and medicine, 2006, Volume: 142, Issue:2

    Topics: Animals; Cerebral Cortex; Chlorides; Convulsants; Epilepsy; Male; Pentylenetetrazole; Rats; Rats, Wistar; Receptors, GABA-A; Synaptic Membranes

2006
Cl(-) conduction of GABAA receptor complex of synaptic membranes in the cortex of rats at the middle stage of chronic cerebral epileptization (pharmacological kindling).
    Bulletin of experimental biology and medicine, 2007, Volume: 144, Issue:5

    Topics: Animals; Cerebral Cortex; Chlorides; Chronic Disease; Dose-Response Relationship, Drug; Epilepsy; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Kindling, Neurologic; Male; Muscimol; Pentylenetetrazole; Rats; Rats, Wistar; Receptors, GABA-A; Seizures; Synaptic Membranes

2007
Cl- conduction of GABA(A)-receptor complex of synaptic membranes of rat brain cortex after development of chronic epileptization of the brain (pharmacological kindling).
    Bulletin of experimental biology and medicine, 2008, Volume: 145, Issue:3

    Topics: Animals; Cerebral Cortex; Chlorides; Chlorine; Kindling, Neurologic; Male; Muscimol; Pentylenetetrazole; Radioisotopes; Rats; Rats, Wistar; Receptors, GABA-A; Synaptic Membranes

2008
Convulsion-related activities of Scutellaria flavones are related to the 5,7-dihydroxyl structures.
    European journal of pharmacology, 2011, Jun-01, Volume: 659, Issue:2-3

    Topics: Animals; Anticonvulsants; Chlorides; Drug Evaluation, Preclinical; Electroshock; Flavones; Hydroxides; Intracellular Space; Male; Motor Activity; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Scutellaria baicalensis; Seizures; Structure-Activity Relationship; Strychnine

2011
The effects of zinc treatment on the blood-brain barrier permeability and brain element levels during convulsions.
    Biological trace element research, 2013, Volume: 151, Issue:2

    Topics: Animals; Blood Pressure; Blood-Brain Barrier; Brain Stem; Cerebellum; Chlorides; Convulsants; Copper; Evans Blue; Magnesium; Pentylenetetrazole; Permeability; Rats; Rats, Wistar; Seizures; Sodium; Zinc; Zinc Compounds

2013
Nitric oxide and glutamate are contributors of anti-seizure activity of rubidium chloride: A comparison with lithium.
    Neuroscience letters, 2019, 08-24, Volume: 708

    Topics: Animals; Anticonvulsants; Chlorides; Glutamic Acid; Lithium Chloride; Male; Mice; Neuroprotective Agents; Nitric Oxide; Pentylenetetrazole; Receptors, N-Methyl-D-Aspartate; Rubidium; Seizures; Signal Transduction

2019
[The influence of ethrane on the electro- and pentylenetetrazol-convulsions in mice (author's transl)].
    Der Anaesthesist, 1975, Volume: 24, Issue:3

    Topics: Anesthesia, Inhalation; Anesthetics; Animals; Anticonvulsants; Chlorine; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Ethers; Female; Fluorine; Lethal Dose 50; Mice; Muscle Cramp; Muscles; Pentylenetetrazole; Seizures

1975
Pharmacology of the adrenergic mechanism.
    Journal of neural transmission, 1974, Volume: Suppl 11, Issue:0

    Topics: Amphetamine; Amphetamines; Animals; Anticonvulsants; Brain; Catecholamines; Cell Nucleus; Central Nervous System Stimulants; Chlorine; Dopamine; Drug Interactions; Guanethidine; Metaraminol; Methamphetamine; Mice; Microsomes; Mitochondria; Norepinephrine; Oxygen Consumption; Pentylenetetrazole; Reserpine; Seizures; Serotonin; Synaptic Transmission; Thyroxine; Time Factors; Tranylcypromine; Tritium; Tyramine

1974
Structure-activity relationships within the class of 1,4-benzodiazepines: presence of chlorine and central nervous system activities.
    Current therapeutic research, clinical and experimental, 1974, Volume: 16, Issue:4

    Topics: Animals; Anticonvulsants; Benzodiazepinones; Chlorine; Drug Synergism; Female; Hexobarbital; Mice; Motor Activity; Muscle Relaxants, Central; Pentylenetetrazole; Sleep; Structure-Activity Relationship; Strychnine

1974
Diazepam metabolism and anticonvulsant activity in newborn animals.
    Biochemical pharmacology, 1973, Dec-01, Volume: 22, Issue:23

    Topics: Age Factors; Animals; Anticonvulsants; Appetite; Appetite Depressants; Brain; Chlorine; Chromatography, Gas; Dealkylation; Diazepam; Dopamine; Guinea Pigs; In Vitro Techniques; Male; Norepinephrine; Pentylenetetrazole; Rats; Serotonin

1973