Compounds > pentylenetetrazole
Page last updated: 2024-08-17

pentylenetetrazole and cannabidiol

pentylenetetrazole has been researched along with cannabidiol in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19905 (26.32)18.7374
1990's1 (5.26)18.2507
2000's0 (0.00)29.6817
2010's6 (31.58)24.3611
2020's7 (36.84)2.80

Authors

AuthorsStudies
Consroe, PF; Wolkin, AL1
Borys, HK; Chiu, P; Karler, R; Turkanis, SA1
Browne, SE; Pertwee, RG; Ross, TM; Stretton, CD1
Calder, LD; Karler, R; Murphy, V; Turkanis, SA1
Calder, LD; Karler, R; Turkanis, SA1
Karler, R; Turkanis, SA1
Bevan, SA; Hill, AJ; Jones, NA; Smith, I; Stephens, GJ; Whalley, BJ; Williams, CM1
Ahmad-Molaei, L; Motamedi, F; Naderi, N; Shirazi-zand, Z1
Cascio, MG; Duncan, M; Hill, AJ; Hill, TD; Pertwee, RG; Romano, B; Whalley, BJ; Williams, CM1
Hill, AJ; Hill, CL; Jones, NA; Smith, I; Stephens, GJ; Whalley, BJ; Williams, CM1
Larson, C; López, HH; Pelz, MC; Schoolcraft, KD; Spring, MG1
Dallas, ML; Hafezi, N; Hu, Y; Mascal, M; Serra, G; Spencer, JPE; Wang, D1
Amsalem, K; Berman, P; Gelfand, A; Lewitus, DY; Lewitus, GM; Meiri, D; Uziel, A1
Ashpole, NM; Carty, DR; Dickson, KE; Thornton, C; Willett, KL1
Hložek, T; Kubová, H; Mareš, P; Páleníček, T; Uttl, L1
Barbosa da Silva, R; Carlini, E; Faber, J; Filev, R; Gimenes, C; Hashiguchi, D; Janisset, NRLL; Longo, BM; Quintella, ML; Romariz, SAA; Yokoyama, T1
Bellozi, PMQ; da Silva, MCM; de Assis Lima, IV; de Oliveira, ACP; Moraes, MFD; Moreira, FA; Pinto, HPP; Vilela, LR1
Forcelli, PA; Quinlan, S; Witherspoon, E1
He, M; Jiang, X; Lu, H; Wang, Q; Wei, M; Zhao, Y1

Reviews

1 review(s) available for pentylenetetrazole and cannabidiol

ArticleYear
Changes in CNS sensitivity to cannabinoids with repeated treatment: tolerance and auxoesthesia.
    NIDA research monograph, 1984, Volume: 54

    Topics: Animals; Brain; Cannabidiol; Cannabinoids; Dronabinol; Drug Tolerance; Electroshock; Kindling, Neurologic; Mice; Pentylenetetrazole; Phenytoin; Picrotoxin; Seizures

1984

Other Studies

18 other study(ies) available for pentylenetetrazole and cannabidiol

ArticleYear
Anticonvulsant interaction of cannabidiol and ethosuximide in rats.
    The Journal of pharmacy and pharmacology, 1977, Volume: 29, Issue:8

    Topics: Animals; Anticonvulsants; Cannabidiol; Cannabinoids; Drug Interactions; Ethosuximide; Male; Pentylenetetrazole; Proadifen; Rats

1977
Influence of delta9-tetrahydrocannabinol and cannabidiol on photically evoked after-discharge potentials.
    Psychopharmacology, 1977, Apr-29, Volume: 52, Issue:2

    Topics: Animals; Anticonvulsants; Cannabidiol; Cannabinoids; Dose-Response Relationship, Drug; Dronabinol; Evoked Potentials; Male; Pentylenetetrazole; Photic Stimulation; Rats; Time Factors

1977
An investigation of the involvement of GABA in certain pharmacological effects of delta-9-tetrahydrocannabinol.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 40, Issue:3

    Topics: Amino Acids; Amino Acids, Neutral; Analgesics; Animals; Anticonvulsants; Body Temperature; Cannabidiol; Dronabinol; Electric Stimulation; Flurazepam; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Nipecotic Acids; Pentylenetetrazole; Seizures; Tiagabine

1991
Pentylenetetrazol kindling in mice.
    Neuropharmacology, 1989, Volume: 28, Issue:8

    Topics: Animals; Anticonvulsants; Aspartic Acid; Brain; Cannabidiol; Electric Stimulation; Kindling, Neurologic; Male; Mice; N-Methylaspartate; Neurotransmitter Agents; Pentylenetetrazole; Picrotoxin

1989
Excitatory and depressant effects of delta 9-tetrahydrocannabinol and cannabidiol on cortical evoked responses in the conscious rat.
    Psychopharmacology, 1981, Volume: 75, Issue:3

    Topics: Animals; Anticonvulsants; Cannabidiol; Cannabinoids; Cerebral Cortex; Convulsants; Dronabinol; Ethosuximide; Evoked Potentials; Pentylenetetrazole; Phenytoin; Rats; Rats, Inbred Strains

1981
Cannabidiol displays antiepileptiform and antiseizure properties in vitro and in vivo.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 332, Issue:2

    Topics: 4-Aminopyridine; Action Potentials; Animals; Anticonvulsants; Cannabidiol; Disease Models, Animal; Female; Guanosine 5'-O-(3-Thiotriphosphate); Hippocampus; In Vitro Techniques; Magnesium; Male; Pentylenetetrazole; Rats; Rats, Inbred WKY; Receptor, Cannabinoid, CB1; Seizures

2010
The role of potassium BK channels in anticonvulsant effect of cannabidiol in pentylenetetrazole and maximal electroshock models of seizure in mice.
    Epilepsy & behavior : E&B, 2013, Volume: 28, Issue:1

    Topics: Analysis of Variance; Animals; Anticonvulsants; Cannabidiol; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Indoles; Injections, Intraventricular; Large-Conductance Calcium-Activated Potassium Channels; Male; Mice; Pentylenetetrazole; Potassium Channel Blockers; Seizures

2013
Cannabidivarin-rich cannabis extracts are anticonvulsant in mouse and rat via a CB1 receptor-independent mechanism.
    British journal of pharmacology, 2013, Volume: 170, Issue:3

    Topics: Animals; Anticonvulsants; Brain; Cannabidiol; Cannabinoids; Cannabis; Disease Models, Animal; Dose-Response Relationship, Drug; Hand Strength; Male; Mice; Mice, Inbred DBA; Motor Activity; Noise; Pentylenetetrazole; Phytotherapy; Pilocarpine; Plant Extracts; Plants, Medicinal; Protein Binding; Rats; Rats, Inbred WKY; Receptor, Cannabinoid, CB1; Seizures

2013
Voltage-gated sodium (NaV) channel blockade by plant cannabinoids does not confer anticonvulsant effects per se.
    Neuroscience letters, 2014, Apr-30, Volume: 566

    Topics: Animals; Anticonvulsants; Cannabidiol; Cannabinoids; Cells, Cultured; Cerebral Cortex; Cricetulus; Female; Hippocampus; Humans; In Vitro Techniques; Male; Mice; Neurons; Patch-Clamp Techniques; Pentylenetetrazole; Rats, Inbred WKY; Seizures; Voltage-Gated Sodium Channel Blockers

2014
Assessing the role of serotonergic receptors in cannabidiol's anticonvulsant efficacy.
    Epilepsy & behavior : E&B, 2017, Volume: 73

    Topics: Animals; Anticonvulsants; Cannabidiol; Fluorobenzenes; Male; Pentylenetetrazole; Piperazines; Piperidines; Pyridines; Rats; Rats, Inbred WKY; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Seizures; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Antagonists; Treatment Outcome

2017
Synthetic, non-intoxicating 8,9-dihydrocannabidiol for the mitigation of seizures.
    Scientific reports, 2019, 05-23, Volume: 9, Issue:1

    Topics: Animals; Anticonvulsants; Cannabidiol; Cannabinoids; Disease Models, Animal; Male; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Treatment Outcome

2019
Full-Spectrum
    ACS applied materials & interfaces, 2020, May-27, Volume: 12, Issue:21

    Topics: Animals; Anticonvulsants; Cannabidiol; Cannabis; Delayed-Action Preparations; Drug Liberation; Mice; Pentylenetetrazole; Plant Extracts; Seizures

2020
Cannabis constituents reduce seizure behavior in chemically-induced and scn1a-mutant zebrafish.
    Epilepsy & behavior : E&B, 2020, Volume: 110

    Topics: Acyclic Monoterpenes; Animals; Animals, Genetically Modified; Anticonvulsants; Cannabidiol; Cannabinoids; Cannabinol; Cannabis; Dose-Response Relationship, Drug; Dronabinol; NAV1.1 Voltage-Gated Sodium Channel; Pentylenetetrazole; Seizures; Zebrafish; Zebrafish Proteins

2020
Anticonvulsive Effects and Pharmacokinetic Profile of Cannabidiol (CBD) in the Pentylenetetrazol (PTZ) or N-Methyl-D-Aspartate (NMDA) Models of Seizures in Infantile Rats.
    International journal of molecular sciences, 2021, Dec-22, Volume: 23, Issue:1

    Topics: Animals; Anticonvulsants; Brain; Cannabidiol; Disease Models, Animal; Epilepsy; Male; N-Methylaspartate; Pentylenetetrazole; Rats; Rats, Wistar; Seizures

2021
Partial protective effects of cannabidiol against PTZ-induced acute seizures in female rats during the proestrus-estrus transition.
    Epilepsy & behavior : E&B, 2022, Volume: 129

    Topics: Animals; Anticonvulsants; Cannabidiol; Disease Models, Animal; Estrus; Female; Humans; Male; Pentylenetetrazole; Proestrus; Rats; Seizures

2022
Cannabidiol effect in pentylenetetrazole-induced seizures depends on PI3K.
    Pharmacological reports : PR, 2022, Volume: 74, Issue:5

    Topics: Animals; Anticonvulsants; Cannabidiol; Mice; Pentylenetetrazole; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Seizures

2022
Preclinical efficacy of cannabidiol for the treatment of early-life seizures.
    Pharmacological reports : PR, 2022, Volume: 74, Issue:5

    Topics: Animals; Anticonvulsants; Cannabidiol; Disease Models, Animal; Epilepsy; Pentylenetetrazole; Rats

2022
The Potential Mechanism of Cannabidiol (CBD) Treatment of Epilepsy in Pentetrazol (PTZ) Kindling Mice Uncovered by Multi-Omics Analysis.
    Molecules (Basel, Switzerland), 2023, Mar-20, Volume: 28, Issue:6

    Topics: Animals; Anticonvulsants; Cannabidiol; Epilepsy; Mice; Multiomics; Pentylenetetrazole; Seizures

2023