pentobarbital has been researched along with propofol in 137 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.73) | 18.7374 |
| 1990's | 49 (35.77) | 18.2507 |
| 2000's | 51 (37.23) | 29.6817 |
| 2010's | 33 (24.09) | 24.3611 |
| 2020's | 3 (2.19) | 2.80 |
| Authors | Studies |
|---|---|
| Altomare, C; Biggio, G; Franco, M; Latrofa, A; Liso, G; Sanna, E; Trapani, G; Usala, M | 1 |
| Asproni, B; Biggio, G; Busonero, F; Cerri, R; Mascia, MP; Pau, A; Sanna, E; Sanna, S; Talani, G | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Prince, RJ; Simmonds, MA | 2 |
| Gibbs, LM; Jewett, BA; Kendig, JJ; Tarasiuk, A | 1 |
| Biggio, G; Concas, A; Maciocco, E; Mascia, MP; Santoro, G | 1 |
| Dolin, SJ; Morris, PJ; Smith, MB; Soar, J | 1 |
| Hales, TG; Lambert, JJ | 1 |
| Collins, JG; Iwasaki, H; Matsumoto, M; Namiki, A; Omote, K; Omote, T; Yamasawa, Y | 1 |
| Biggio, G; Concas, A; Mascia, MP; Sanna, E; Santoro, G; Serra, M | 1 |
| Elias, E; Freeman, JF; Mills, CO; Salt, PJ | 1 |
| Frenkel, C; Urban, BW | 1 |
| Garau, F; Harris, RA; Sanna, E | 1 |
| Gaal, DJ; Jaeger, DD; Kain, TS; Kain, ZN; Rimar, S | 1 |
| Crosby, G; Goto, T; Marota, JJ | 1 |
| Franks, NP; Hall, AC; Lieb, WR | 1 |
| Biggio, G; Concas, A; Dazzi, L; Maciocco, E; Mascia, MP; Santoro, G | 1 |
| Choi, KT; Illievich, UM; Scheller, MS; Strnat, MA; Zornow, MH | 1 |
| Allen, SL; Brammer, A; West, CD | 1 |
| Drummer, HL; Hasan, ZA; Tubbs, T; Woolley, DE; Zimmer, L | 1 |
| Duch, DS; Frenkel, C; Urban, BW | 1 |
| Gelb, AW; Krassioukov, AV; Weaver, LC | 1 |
| Einhaus, SL; Hilton, DL; Meric, AL; Park, MR; Robertson, JT; Schweitzer, JB; White, RP | 1 |
| Bloomfield, EL; Caplin, A; Ebrahim, ZY; Goske, MJ; Hayden, J; Masaryk, TJ; Obuchowski, NA; Ross, JS; Ruggieri, PM; Schubert, A | 1 |
| Bloomfield, EL | 1 |
| Biggio, G; Ghiani, CA; Maciocco, E; Sanna, E; Serra, M; Tuligi, G | 1 |
| Coderre, TJ; Gilron, I | 1 |
| Chang, CL; Chang, YH; Cheng, JT; Lee, JC; Tseng, CC | 1 |
| Koskinen, LO; Larsson, JE; Wahlström, G | 1 |
| Todd, MM; Weeks, J | 1 |
| Davies, PA; Hales, TG; Hanna, MC; Kirkness, EF | 1 |
| Belelli, D; Hill-Venning, C; Lambert, JJ; Peters, JA | 1 |
| Davies, PA; Hales, TG; Kirkness, EF | 1 |
| Fillenz, M; Miele, M | 1 |
| Kano, T; Muteki, T; Sugiyama, K | 1 |
| Brinkhous, A; Dexter, F; Pearlstein, R; Pittman, JE; Sheng, H; Warner, DS | 1 |
| Giannotta, SL; Lavine, SD; Levy, ML; Masri, LS | 1 |
| Belelli, D; Lambert, JJ; Peters, JA; Pistis, M | 2 |
| Davies, M; Dunn, SM; Thuynsma, RP | 1 |
| Tommasino, C | 1 |
| Ito, Y; Iwatsuki, N; Izumi, H; Karita, K; Sato, M | 1 |
| Belelli, D; Lambert, JJ; McGurk, K; Peters, JA; Pistis, M | 1 |
| Coderre, TJ; Gilron, I; Quirion, R | 1 |
| Isshiki, A; Ito, H; Uchino, H; Watanabe, Y | 1 |
| Fung, D; Gronert, GA; Haskins, SC; Steffey, EP | 1 |
| Fukami, S; Mashimo, T; Takenoshita, M; Uchida, I; Yoshiya, I | 1 |
| Guertin, PA; Hounsgaard, J | 1 |
| Duch, DS; Rehberg, B | 1 |
| Chen, CL; Chiu, TH; Yang, YR | 1 |
| Carlson, BX; Engblom, AC; Kristiansen, U; Olsen, RW; Schousboe, A | 2 |
| Barann, M; Bönisch, H; Dilger, JP; Dybek, A; Göthert, M; Urban, BW | 1 |
| Clark, SC; Dark, JH; Flecknell, PA; Khanna, R; Roughan, JV; Sudarshan, CD | 1 |
| Clark, A; Little, HJ; Watson, WP | 1 |
| Dohi, S; Hamaya, Y; Nakashima, S; Nozawa, Y; Takeda, T | 1 |
| Akamatsu, S; Dohi, S; Kato, K; Kozawa, O; Matsuno, H; Niwa, M; Tanabe, K; Uematsu, T; Yamamoto, T | 1 |
| Engelman, E; Gilbart, E; Schmartz, D; Van der Linden, P; Vincent, JL | 1 |
| Empson, RM; Newberry, NR; Sheardown, MJ | 1 |
| Cechetto, DF; Diab, T; Gelb, AW; Gibson, CJ | 1 |
| Simmonds, MA; Sooksawate, T | 1 |
| Bosnjak, ZJ; Hogan, QH; Kohro, S; Nakae, Y; Yamakage, M | 1 |
| Holmes, GL; Menache, CC; Riviello, JJ; Sahin, M | 1 |
| Claassen, J; Emerson, RG; Hirsch, LJ; Mayer, SA | 1 |
| Hioki, K; Koizumi, T; Maeda, H | 1 |
| Lu, H; Xu, TL | 1 |
| Coplin, WM; Formea, CM; Parker, D; Rhoney, DH; Yap, C | 1 |
| Hemmings, HC; Pashkov, VN | 1 |
| Archer, DP; Roth, SH; Samanani, N; Wang, B | 1 |
| Minami, K; Ogata, J; Okamoto, T; Shigematsu, A; Shiraishi, M; Ueta, Y; Uezono, Y | 1 |
| Chang, CS; Olcese, R; Olsen, RW | 1 |
| Daniels, S; Hadipour-Jahromy, M | 1 |
| Thompson, SA; Usala, M; Wafford, KA; Whiting, PJ | 1 |
| Cadete, RA; Gullo, A; Nascimento, CS; Negri, EM; Peratoner, A; Rocco, PR; Santana, MC; Zin, WA | 1 |
| Bramstedt, KA; Morris, HH; Tanner, A | 1 |
| D'Orio, V; Dogné, JM; Gerard, P; Ghuysen, A; Kolh, P; Lambermont, B; Larbuisson, R; Limet, R; Tchana-Sato, V | 1 |
| Brimelow, BC; Joksovic, PM; Murbartián, J; Perez-Reyes, E; Todorovic, SM | 1 |
| Kobayashi, E; Mishina, M; Murayama, T; Sato, Y; Seo, N | 1 |
| Asproni, B; Biggio, G; Busonero, F; Cerri, R; Maciocco, E; Mascia, MP; Pau, A; Sanna, E; Talani, G | 1 |
| Kang, QY; Li, J; Liu, Y; Zhang, PB; Zhao, JJ | 1 |
| Alexander, H; Clark, RS; Dixon, CE; Jenkins, L; Kochanek, PM; Statler, KD; Vagni, V | 1 |
| Fukuda, K; Iida, H; Matsuura, S; Shirakami, G; Tanimoto, K | 1 |
| Chen, CL; Chiu, TH; Tang, JS; Yang, YR | 1 |
| Cox, T; Dalal, PG; McAllister, J; Murray, D; Snider, R | 1 |
| Hudetz, AG; Imas, O; Jugovac, I | 1 |
| Iwata, K; Kitagawa, J; Kondo, M; Kubota, I; Masuda, Y; Oi, Y; Shoda, E; Tsuboi, Y | 1 |
| Braun, HA; Raines, DE; Rüsch, D; Schuster, A; Wulf, H | 1 |
| Anghelescu, DL; Pershad, J; Wan, J | 1 |
| Isshiki, A; Matsuda, M; Matsumoto, S; Noguchi, M; Watanabe, Y | 1 |
| Friesen, RH; Malviya, S; Sadhasivam, S; Tait, AR; Voepel-Lewis, T; Watcha, MF | 1 |
| Csanády, M; Csík, N; Farkas, A; Farkas, AS; Forster, T; Leprán, I; Makra, P; Papp, JG; Rudas, L; Varró, A; Vincze, D | 1 |
| Shankar, VR | 1 |
| D'Angelo, M; Fontaine, PJ; Mason, KP; Zgleszewski, SE; Zurakowski, D | 1 |
| Betts, BA; Gill, N; Griffith, TN; Hall, AC; Humbert, DJ; Jenkins, A; Kelly, EW; Kotey, FO; Rowan, KC; Veneskey, KC; Watt, EE | 1 |
| Aller, MI; Korpi, ER; Leppä, E; Linden, AM; Rosenberg, PH; Wisden, W | 1 |
| Gartner, G; Halwachs-Baumann, G; Kalcher, K; März, W; Meinitzer, A; Stettin, M | 1 |
| Cutter, TW | 1 |
| Iwata, K; Kitagawa, J; Kondo, M; Masuda, Y; Miyamoto, M; Nitta-Kubota, I; Oi, Y; Ren, K; Shoda, E; Suzuki, I; Tsuboi, Y | 1 |
| Leung, LS; Long, JJ; Luo, T; McMurran, TJ; Shen, B; Stewart, L | 1 |
| Baxter, AL; Kost, SI; Mallory, MD | 1 |
| Goepfert, MS; Schulte-Uentrop, L | 1 |
| Sammons, HM; Starkey, E | 1 |
| Gulati, S; Lodha, R; Raj, D | 1 |
| Patel, A; Szarlej, D; Wordell, C | 1 |
| Brown, C | 1 |
| Leung, LS; Luo, T | 1 |
| Ikemoto, Y; Ito, S; Kitahara, S; Sugiyama, H; Yokoyama, T | 1 |
| Dong, J; Li, P; Liu, YF; Luo, J; Min, S; Wei, K | 1 |
| Hall, WJ; Markos, F; Ruane-O'Hora, T | 1 |
| Kim, CB; Nork, TM; Ver Hoeve, JN | 1 |
| Brückner, M; Schwedes, CS | 1 |
| Alldredge, B; Bell, R; Bleck, TP; Brophy, GM; Claassen, J; Glauser, T; LaRoche, SM; Riviello, JJ; Shutter, L; Sperling, MR; Treiman, DM; Vespa, PM | 1 |
| Boku, A; Hanamoto, H; Kudo, C; Morimoto, Y; Niwa, H; Sugimura, M; Toyama, M | 1 |
| DiFrancesco, MW; Holland, SK; Karunanayaka, P; Robertson, SA | 1 |
| Hamaguchi, S; Takasusuki, T; Yaksh, TL; Yamaguchi, S | 1 |
| Hu, G; Lü, YL; Tu, WF; Zeng, YM; Zhou, QM | 1 |
| Dyer, O | 1 |
| Bosco, G; Camporesi, EM; Chaparro, RE; Erasso, D; Gordon, M; Karlnoski, R; Mangar, D; Morgan, D; Paoli, A; Parmagnani, A; Quiroga, C; Rubini, A | 1 |
| Hirota, K; Imaizumi, T; Kushikata, T; Kuwasako, K; Matsuzaki, Y; Murakami, M; Niwa, H; Ohba, T; Ono, K; Sawamura, D; Shintaku, T | 1 |
| Arbour, RB; Dissin, J | 1 |
| Akk, G; Li, P | 1 |
| Dai, RP; Li, CQ; Luo, C; Luo, W; Xu, JM; Zhang, YL; Zhou, FH | 1 |
| Baur, R; Maldifassi, MC; Sigel, E | 1 |
| Brüssow, KP; Daş, G; Görs, S; Kanitz, E; Metges, CC; Vernunft, A; Weitzel, JM | 1 |
| Maldifassi, MC; Sigel, E | 1 |
| Czajkowski, C; Ghosh, B; Tsao, TW | 1 |
| Fu, HL; Lu, Y; Sun, HJ; Wang, HW; Wang, SR; Xu, WY; Yang, F; Yao, XY; Yuan, HB; Zhang, H | 1 |
| Behmenburg, F; Brandenburger, T; Bunte, S; Heinen, A; Hollmann, MW; Huhn, R; van Caster, P | 1 |
| Akk, G; Germann, AL; Shin, DJ; Steinbach, JH | 1 |
| Bullock, JM; Lanaux, TM; Shmalberg, JW | 1 |
| Akk, G; Burbridge, AB; Germann, AL; Pierce, SR; Steinbach, JH | 1 |
| Cao, M; Fei, G; Ge, C; Xie, Y | 1 |
| Akk, G; Burbridge, AB; Germann, AL; Pierce, SR | 1 |
| Fedorov, A; Klein, J; Lehto, A | 1 |
7 review(s) available for pentobarbital and propofol
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Treatment of refractory status epilepticus with pentobarbital, propofol, or midazolam: a systematic review.
Topics: Anticonvulsants; GABA Modulators; Humans; Midazolam; Pentobarbital; Propofol; Status Epilepticus | 2002 |
Effect of age and sedative agent on the accuracy of bispectral index in detecting depth of sedation in children.
Topics: Adolescent; Age Factors; Analgesics, Opioid; Anesthetics, Dissociative; Child; Child, Preschool; Chloral Hydrate; Conscious Sedation; Electroencephalography; Humans; Hypnotics and Sedatives; Infant; Infant, Newborn; Ketamine; Midazolam; Pentobarbital; Propofol; ROC Curve; Sensitivity and Specificity | 2007 |
Sedating children for radiological procedures: an intensivist's perspective.
Topics: Child; Conscious Sedation; Critical Care; Deep Sedation; Humans; Hypnotics and Sedatives; Magnetic Resonance Imaging; Pentobarbital; Practice Guidelines as Topic; Propofol; Radiology; Radiology, Interventional; Tomography, X-Ray Computed | 2008 |
Anaesthesia or sedation for MRI in children.
Topics: Anesthesia; Anesthetics, Dissociative; Anesthetics, Intravenous; Child; Chloral Hydrate; Conscious Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Ketamine; Magnetic Resonance Imaging; Midazolam; Pentobarbital; Propofol | 2010 |
Sedation for radiological imaging.
Topics: Child; Chloral Hydrate; Conscious Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intestinal Absorption; Ketamine; Magnetic Resonance Imaging; Midazolam; Pentobarbital; Propofol; Temazepam; Thiopental; Tomography, X-Ray Computed | 2011 |
Alternatives to sodium amobarbital in the Wada test.
Topics: Amobarbital; Anesthetics, Intravenous; Diagnostic Techniques, Neurological; Dominance, Cerebral; Etomidate; Humans; Methohexital; Neuropsychological Tests; Pentobarbital; Propofol | 2011 |
3 trial(s) available for pentobarbital and propofol
| Article | Year |
|---|---|
A first-pass cost analysis of propofol versus barbiturates for children undergoing magnetic resonance imaging.
Topics: Anesthesia Recovery Period; Anesthesiology; Child; Child, Preschool; Consciousness; Drug Therapy; Humans; Infant; Infusions, Intravenous; Magnetic Resonance Imaging; Pentobarbital; Propofol; Thiopental | 1994 |
Comparison of propofol with pentobarbital/midazolam/fentanyl sedation for magnetic resonance imaging of the brain in children.
Topics: Adjuvants, Anesthesia; Adolescent; Anesthesia Recovery Period; Brain; Caregivers; Child; Child, Preschool; Drug Therapy, Combination; Female; Fentanyl; Humans; Hypnotics and Sedatives; Infant; Infusions, Intravenous; Magnetic Resonance Imaging; Male; Midazolam; Patient Satisfaction; Pentobarbital; Propofol; Prospective Studies; Treatment Outcome | 2007 |
BOLD fMRI in infants under sedation: Comparing the impact of pentobarbital and propofol on auditory and language activation.
Topics: Brain Mapping; Female; Humans; Hypnotics and Sedatives; Infant; Language; Magnetic Resonance Imaging; Male; Pentobarbital; Propofol; Somatosensory Cortex; Speech Perception | 2013 |
127 other study(ies) available for pentobarbital and propofol
| Article | Year |
|---|---|
Propofol analogues. Synthesis, relationships between structure and affinity at GABAA receptor in rat brain, and differential electrophysiological profile at recombinant human GABAA receptors.
Topics: Anesthetics, Intravenous; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chloride Channel Agonists; Female; Humans; In Vitro Techniques; Oocytes; Patch-Clamp Techniques; Propofol; Rats; Receptors, GABA-A; Recombinant Proteins; Structure-Activity Relationship; Xenopus laevis | 1998 |
Synthesis, structure-activity relationships at the GABA(A) receptor in rat brain, and differential electrophysiological profile at the recombinant human GABA(A) receptor of a series of substituted 1,2-diphenylimidazoles.
Topics: Amino Acid Sequence; Animals; Behavior, Animal; Brain; Female; GABA-A Receptor Agonists; Humans; Imidazoles; In Vitro Techniques; Male; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Protein Subunits; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Recombinant Proteins; Reflex; Stereoisomerism; Structure-Activity Relationship; Xenopus laevis | 2005 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Temperature and anion dependence of allosteric interactions at the gamma-aminobutyric acid-benzodiazepine receptor.
Topics: Animals; Anions; Binding, Competitive; Brain Chemistry; Drug Interactions; Flunitrazepam; Male; Pentobarbital; Pregnanediones; Propofol; Rats; Rats, Wistar; Receptors, GABA-A; Temperature | 1992 |
Propofol and barbiturate depression of spinal nociceptive neurotransmission.
Topics: Animals; Animals, Newborn; Depression, Chemical; Hyperalgesia; In Vitro Techniques; Pain; Pentobarbital; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Spinal Cord; Spinal Nerve Roots; Synaptic Transmission; Thiopental | 1992 |
Propofol potentiates the binding of [3H]flunitrazepam to the GABAA receptor complex.
Topics: Animals; Binding, Competitive; Drug Synergism; Flunitrazepam; Male; Pentobarbital; Pregnanediones; Propofol; Rats; Rats, Wistar; Receptors, GABA-A; Tritium | 1992 |
The general anesthetic propofol: a biochemical tool to study the function of the GABA-coupled chloride channel.
Topics: Anesthetics; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; gamma-Aminobutyric Acid; Ion Channels; Male; Pentobarbital; Pregnanediones; Propofol; Rats; Rats, Inbred Strains | 1992 |
Does glycine antagonism underlie the excitatory effects of methohexitone and propofol?
Topics: Anesthesia, General; Animals; Bicuculline; Central Nervous System; Electroencephalography; Ethanol; Glycine; Male; Methohexital; Mice; Mice, Inbred Strains; Pentobarbital; Propofol; Seizures; Strychnine | 1992 |
The actions of propofol on inhibitory amino acid receptors of bovine adrenomedullary chromaffin cells and rodent central neurones.
Topics: Adrenal Medulla; Animals; Cattle; Cells, Cultured; Cerebral Cortex; Chromaffin System; Electric Stimulation; Female; Flumazenil; GABA-A Receptor Antagonists; Ion Channel Gating; Mice; Neural Conduction; Neurons; Pentobarbital; Pregnancy; Propofol; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, Glycine; Receptors, Neurotransmitter | 1991 |
[Comparison of the effect of propofol and that of pentobarbital on behavioral responses to somatic and visceral stimuli in rats].
Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Male; Pain; Pentobarbital; Propofol; Rats; Rats, Inbred Strains; Sensory Thresholds; Tail; Viscera | 1991 |
The general anesthetic propofol enhances the function of gamma-aminobutyric acid-coupled chloride channel in the rat cerebral cortex.
Topics: Anesthetics; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chloride Channels; gamma-Aminobutyric Acid; Male; Membrane Proteins; Pentobarbital; Picrotoxin; Pregnanediones; Propofol; Rats; Rats, Inbred Strains | 1990 |
Effect of anaesthetic agents on bile flow and biliary excretion of 131I-cholylglycyltyrosine in the rat.
Topics: Alfaxalone Alfadolone Mixture; Anesthetics; Animals; Bile; Etomidate; Glycocholic Acid; Kinetics; Male; Pentobarbital; Phenols; Propofol; Rats; Rats, Inbred Strains | 1989 |
[Interactions of intravenous anesthetics with human CNS ion channels. Electrophysiologic studies with a new type of voltage clamp technique].
Topics: Brain; Electrophysiology; Humans; Ion Channels; Ketamine; Midazolam; Pentobarbital; Propofol | 1994 |
Novel properties of homomeric beta 1 gamma-aminobutyric acid type A receptors: actions of the anesthetics propofol and pentobarbital.
Topics: Animals; Bicuculline; Female; gamma-Aminobutyric Acid; Pentobarbital; Picrotoxin; Propofol; Receptors, GABA-A; Strychnine; Xenopus laevis | 1995 |
Pentobarbitone, but not propofol, produces pre-emptive analgesia in the rat formalin model.
Topics: Analgesics; Anesthesia, Intravenous; Animals; Behavior, Animal; Disease Models, Animal; Formaldehyde; Male; Pain; Pentobarbital; Picrotoxin; Propofol; Rats; Rats, Sprague-Dawley; Time Factors | 1994 |
Insensitivity of P-type calcium channels to inhalational and intravenous general anesthetics.
Topics: Administration, Inhalation; Anesthesia, General; Anesthetics; Animals; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Ethanol; Halothane; Injections, Intravenous; Ion Channel Gating; Isoflurane; Kinetics; Membrane Potentials; Pentobarbital; Propofol; Purkinje Cells; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Thiopental | 1994 |
Effects of propofol, pentobarbital and alphaxalone on t-[35S]butylbicyclophosphorothionate binding in rat cerebral cortex.
Topics: Anesthetics; Animals; Bicuculline; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chloride Channels; Diazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channel Gating; Male; Membranes; Pentobarbital; Pregnanediones; Propofol; Rats; Rats, Sprague-Dawley; Sulfur Radioisotopes | 1994 |
Effects of hypothermia or anesthetics on hippocampal glutamate and glycine concentrations after repeated transient global cerebral ischemia.
Topics: Animals; Female; Glutamates; Glycine; Hippocampus; Hypothermia, Induced; Ischemic Attack, Transient; Isoflurane; Male; Pentobarbital; Propofol; Rabbits | 1994 |
A comparison of propofol with other injectable anaesthetics in a rat model for measuring cardiovascular parameters.
Topics: Anesthesia, Intravenous; Anesthetics; Animals; Blood Pressure; Butyrophenones; Female; Fentanyl; Heart Rate; Male; Midazolam; Pentobarbital; Pregnanediones; Propofol; Rats; Respiration; Thiopental | 1993 |
Comparison of the effects of propofol, diazepam and pentobarbital on hippocampal potentials evoked by prepyriform stimulation in the freely behaving rat.
Topics: Animals; Behavior, Animal; Cerebral Cortex; Diazepam; Electric Stimulation; Electroencephalography; Evoked Potentials; Female; Hippocampus; Pentobarbital; Picrotoxin; Propofol; Rats; Sleep | 1993 |
Effects of i.v. anaesthetics on human brain sodium channels.
Topics: Anesthesia, Intravenous; Anesthetics; Brain; Dose-Response Relationship, Drug; Electrophysiology; Humans; Ion Channel Gating; Pentobarbital; Propofol; Sodium Channels | 1993 |
Action of propofol on central sympathetic mechanisms controlling blood pressure.
Topics: Action Potentials; Animals; Blood Pressure; Dose-Response Relationship, Drug; Glycine; Heart Rate; Infusions, Intravenous; Injections, Intravenous; Kidney; Male; Medulla Oblongata; Pentobarbital; Pressoreceptors; Propofol; Rats; Rats, Wistar; Sympathetic Nervous System; Time Factors; Vasomotor System | 1993 |
Early assessment of neurologic deficits in the fluid percussion model of brain injury.
Topics: Anesthesia; Animals; Behavior, Animal; Blood Pressure; Brain Injuries; Brain Stem; Cats; Cerebral Hemorrhage; Coma; Disease Models, Animal; Eyelids; Female; Male; Mesencephalon; Movement; Nervous System; Pentobarbital; Propofol | 1993 |
Intravenous sedation for MR imaging of the brain and spine in children: pentobarbital versus propofol.
Topics: Brain; Child; Child, Preschool; Conscious Sedation; Humans; Magnetic Resonance Imaging; Pentobarbital; Propofol; Prospective Studies; Spine | 1993 |
Propofol for sedation of pediatric patients.
Topics: Child; Humans; Hypnotics and Sedatives; Pentobarbital; Propofol; Radiology | 1993 |
Biochemical evaluations of the effects of loreclezole and propofol on the GABAA receptor in rat brain.
Topics: Anesthetics; Animals; Anticonvulsants; Brain; Bridged Bicyclo Compounds, Heterocyclic; Diazepam; Flunitrazepam; GABA Modulators; gamma-Aminobutyric Acid; Hypnotics and Sedatives; In Vitro Techniques; Male; Muscimol; Pentobarbital; Pregnanediones; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sulfur Radioisotopes; Triazoles; Tritium | 1996 |
Preemptive analgesic effects of steroid anesthesia with alphaxalone in the rat formalin test. Evidence for differential GABA(A) Receptor modulation in persistent nociception.
Topics: Analgesics; Anesthetics; Animals; GABA Modulators; Male; Pentobarbital; Pregnanediones; Propofol; Rats; Receptors, GABA-A | 1996 |
Decrease of anesthetics activity by electroacupuncture on Jen-Chung point in rabbits.
Topics: Acupuncture Analgesia; Acupuncture Points; Anesthetics; Animals; Electric Stimulation; Electroacupuncture; Female; Fenclonine; Hypnotics and Sedatives; Injections, Intravenous; Male; Pentobarbital; Propofol; Rabbits; Serotonin; Sleep; Time Factors | 1995 |
Effects of TRH and atropine on induction and duration of anesthesia with propofol in rats.
Topics: Anesthesia; Animals; Atropine; Drug Interactions; Male; Pentobarbital; Piloerection; Propofol; Rats; Rats, Sprague-Dawley; Thyrotropin-Releasing Hormone; Tremor | 1996 |
Comparative effects of propofol, pentobarbital, and isoflurane on cerebral blood flow and blood volume.
Topics: Adjuvants, Anesthesia; Analysis of Variance; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Blood Volume; Brain; Carbon Radioisotopes; Cerebrovascular Circulation; Dextrans; Erythrocyte Volume; Erythrocytes; Hematocrit; Intracranial Pressure; Isoflurane; Male; Nicotine; Pentobarbital; Plasma Volume; Propofol; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Technetium; Tritium | 1996 |
Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit.
Topics: Amino Acid Sequence; Anesthetics, Intravenous; Animals; Bicuculline; Brain; Cell Line; Consensus Sequence; DNA, Complementary; Flumazenil; Flunitrazepam; GABA Agents; gamma-Aminobutyric Acid; Humans; Molecular Sequence Data; Muscimol; Pentobarbital; Picrotoxin; Pregnanolone; Propofol; Rats; Receptors, GABA-A; Recombinant Proteins; RNA, Messenger; Transfection | 1997 |
Subunit-dependent interaction of the general anaesthetic etomidate with the gamma-aminobutyric acid type A receptor.
Topics: Anesthetics, Intravenous; Animals; Etomidate; Humans; Pentobarbital; Pregnanolone; Propofol; Receptors, GABA-A; Recombinant Proteins; Xenopus laevis | 1997 |
Modulation by general anaesthetics of rat GABAA receptors comprised of alpha 1 beta 3 and beta 3 subunits expressed in human embryonic kidney 293 cells.
Topics: Anesthetics, General; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Transformed; gamma-Aminobutyric Acid; Humans; Pentobarbital; Pregnanolone; Propofol; Radioligand Assay; Rats; Receptors, GABA-A; Recombinant Proteins; Sulfur Radioisotopes | 1997 |
Changes in extracellular brain ascorbate in rat striatum in response to administration of non-volatile anaesthetic agents.
Topics: Anesthetics, Intravenous; Animals; Ascorbic Acid; Biomarkers; Corpus Striatum; Extracellular Space; Male; Pentobarbital; Propofol; Rats; Rats, Sprague-Dawley | 1997 |
[Intravenous anesthetics, acting on the gamma-amino butric acid (GABA)A receptor, potentiate the herbal medicine "saiko-keishi-to"-induced chloride current].
Topics: Anesthetics, Intravenous; Animals; Anticonvulsants; Cells, Cultured; Chlorine; Diazepam; Drug Synergism; Drugs, Chinese Herbal; GABA Modulators; GABA-A Receptor Agonists; Pentobarbital; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Stimulation, Chemical | 1997 |
Comparison of the effects of propofol and pentobarbital on neurologic outcome and cerebral infarct size after temporary focal ischemia in the rat.
Topics: Anesthetics, Intravenous; Animals; Brain; Cerebral Infarction; Electroencephalography; Ischemic Attack, Transient; Male; Pentobarbital; Propofol; Rats; Rats, Wistar | 1997 |
Temporary occlusion of the middle cerebral artery in intracranial aneurysm surgery: time limitation and advantage of brain protection.
Topics: Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; Aneurysm, Ruptured; Brain Ischemia; Cerebral Arteries; Cerebral Infarction; Cerebrovascular Circulation; Constriction; Electroencephalography; Etomidate; Female; Humans; Iatrogenic Disease; Intracranial Aneurysm; Ischemic Attack, Transient; Isoflurane; Male; Microsurgery; Middle Aged; Neuroprotective Agents; Pentobarbital; Propofol; Radiography; Retrospective Studies; Risk Factors; Subarachnoid Hemorrhage; Time Factors | 1997 |
The interaction of general anaesthetics with recombinant GABAA and glycine receptors expressed in Xenopus laevis oocytes: a comparative study.
Topics: Anesthetics, Intravenous; Animals; Dose-Response Relationship, Drug; Etomidate; GABA Modulators; Humans; Oocytes; Pentobarbital; Propofol; Rats; Receptors, GABA-A; Receptors, Glycine; Xenopus laevis | 1997 |
Effects of propofol and pentobarbital on ligand binding to GABAA receptors suggest a similar mechanism of action.
Topics: Allosteric Site; Anesthetics, Intravenous; Animals; Azides; Benzodiazepines; Brain; Cattle; Flunitrazepam; GABA Agonists; In Vitro Techniques; Ligands; Membranes; Muscimol; Pentobarbital; Propofol; Receptors, GABA-A | 1998 |
Is lack of statistical power always evidence of lack of effect?
Topics: Anesthetics; Animals; Brain; Cerebral Infarction; Ischemic Attack, Transient; Pentobarbital; Propofol; Rats | 1998 |
Suppression of parasympathetic reflex vasodilatation in the lower lip of the cat by isoflurane, propofol, ketamine and pentobarbital: implications for mechanisms underlying the production of anaesthesia.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Cats; Dose-Response Relationship, Drug; Electric Stimulation; Female; GABA Antagonists; Hypnotics and Sedatives; Isoflurane; Ketamine; Lip; Male; Parasympathetic Nervous System; Pentobarbital; Picrotoxin; Propofol; Reflex; Vasodilation | 1998 |
Complementary regulation of anaesthetic activation of human (alpha6beta3gamma2L) and Drosophila (RDL) GABA receptors by a single amino acid residue.
Topics: Amino Acids; Anesthetics, General; Anesthetics, Intravenous; Animals; Biotransformation; Cells, Cultured; Drosophila; Electrophysiology; GABA Modulators; gamma-Aminobutyric Acid; Humans; Membrane Potentials; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Pentobarbital; Propofol; Receptors, GABA; Xenopus laevis | 1999 |
Pre- versus postinjury effects of intravenous GABAergic anesthetics on formalin-induced Fos immunoreactivity in the rat spinal cord.
Topics: Adjuvants, Anesthesia; Analgesics; Analysis of Variance; Anesthetics; Anesthetics, Intravenous; Animals; Cell Nucleus; Coloring Agents; Cytoplasm; Disease Models, Animal; Fixatives; Formaldehyde; GABA Modulators; Immunoenzyme Techniques; Injections, Subcutaneous; Lumbar Vertebrae; Male; Pentobarbital; Pregnanediones; Propofol; Proto-Oncogene Proteins c-fos; Rats; Rats, Long-Evans; Spinal Cord | 1999 |
Neuroprotective properties of propofol and midazolam, but not pentobarbital, on neuronal damage induced by forebrain ischemia, based on the GABAA receptors.
Topics: Anesthetics, Intravenous; Animals; Baclofen; Brain Ischemia; Dose-Response Relationship, Drug; GABA Agonists; GABA Modulators; Gerbillinae; Histocytochemistry; Male; Midazolam; Muscimol; Neurons; Neuroprotective Agents; Pentobarbital; Propofol; Prosencephalon; Receptors, GABA-A; Reperfusion Injury | 1999 |
Plasma electrolyte and metabolite concentrations associated with pentobarbital or pentobarbital-propofol anesthesia during three weeks' mechanical ventilation and intensive care in dogs.
Topics: Anesthesia, Intravenous; Anesthetics, Combined; Animals; Blood Gas Analysis; Critical Care; Dogs; Electrolytes; Erythrocyte Count; Leukocyte Count; Parathyroid Hormone; Pentobarbital; Propofol; Respiration, Artificial; Triglycerides | 1998 |
The effects of a point mutation of the beta2 subunit of GABA(A) receptor on direct and modulatory actions of general anesthetics.
Topics: Amino Acid Substitution; Anesthetics, General; Animals; Chloride Channels; Dose-Response Relationship, Drug; Etomidate; GABA Modulators; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Membrane Potentials; Mice; Oocytes; Pentobarbital; Phenylalanine; Point Mutation; Propofol; Receptors, GABA-A; Tyrosine; Xenopus laevis | 1999 |
Non-volatile general anaesthetics reduce spinal activity by suppressing plateau potentials.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Adjuvants, Anesthesia; Anesthetics, Intravenous; Animals; Bicuculline; Calcium Channel Agonists; Calcium Channels; Calcium Channels, L-Type; Excitatory Postsynaptic Potentials; GABA Antagonists; Interneurons; Motor Neurons; Pentobarbital; Propofol; Receptors, GABA-A; Serotonin; Spinal Cord; Tetrodotoxin; Thiopental; Turtles | 1999 |
The interaction of general anaesthetics and neurosteroids with GABA(A) and glycine receptors.
Topics: Anesthetics; Animals; Drug Interactions; Electric Conductivity; Etomidate; Female; gamma-Aminobutyric Acid; Glycine; Mutagenesis, Site-Directed; Oocytes; Pentobarbital; Pregnanolone; Propofol; Receptors, GABA-A; Receptors, Glycine; Recombinant Proteins; Structure-Activity Relationship; Xenopus laevis | 1999 |
Suppression of central nervous system sodium channels by propofol.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Brain; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Pentobarbital; Propofol; Rats; Sodium Channel Blockers | 1999 |
Activation of rat locus coeruleus neuron GABA(A) receptors by propofol and its potentiation by pentobarbital or alphaxalone.
Topics: Anesthetics; Anesthetics, Intravenous; Animals; Baclofen; Barium Compounds; Bicuculline; Chlorides; Diazepam; Drug Synergism; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Ionophores; Locus Coeruleus; Male; Neurons; Pentobarbital; Picrotoxin; Pregnanediones; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Zinc Compounds | 1999 |
A single glycine residue at the entrance to the first membrane-spanning domain of the gamma-aminobutyric acid type A receptor beta(2) subunit affects allosteric sensitivity to GABA and anesthetics.
Topics: Allosteric Regulation; Amino Acid Sequence; Anesthetics; Animals; Cells, Cultured; Chloride Channels; Electrophysiology; Etomidate; GABA Modulators; gamma-Aminobutyric Acid; Glycine; Ligands; Molecular Sequence Data; Mutagenesis, Site-Directed; Pentobarbital; Pregnanediones; Propofol; Protein Conformation; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Sequence Homology, Amino Acid; Spodoptera | 2000 |
Inhibition of 5-HT3 receptors by propofol: equilibrium and kinetic measurements.
Topics: Anesthetics, General; Animals; Binding Sites; Cell Line; Guanidine; Ion Channel Gating; Kinetics; Mice; Patch-Clamp Techniques; Pentobarbital; Propofol; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists | 2000 |
A new porcine model of reperfusion injury after lung transplantation.
Topics: Animals; Azaperone; Disease Models, Animal; Female; Hypnotics and Sedatives; Lung Transplantation; Pentobarbital; Pneumonectomy; Propofol; Pulmonary Ventilation; Reperfusion; Reperfusion Injury; Swine; Thoracotomy; Tissue Donors; Ventilators, Mechanical | 1999 |
Investigations into pharmacological antagonism of general anaesthesia.
Topics: Anesthesia, General; Anesthetics, General; Animals; Convulsants; Ethanol; Ketamine; Male; Mice; Pentobarbital; Propofol; Thyrotropin-Releasing Hormone | 2000 |
The effects of pentobarbital, isoflurane, and propofol on immediate-early gene expression in the vital organs of the rat.
Topics: Adjuvants, Anesthesia; Anesthetics; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Brain; Gene Expression; Genes, Immediate-Early; Isoflurane; Kidney; Liver; Male; Myocardium; Pentobarbital; Peptidylprolyl Isomerase; Propofol; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2000 |
Pentobarbital, but not propofol, suppresses vasopressin-stimulated heat shock protein 27 induction in aortic smooth muscle cells.
Topics: Anesthetics, Intravenous; Animals; Aorta; Blotting, Northern; Blotting, Western; Cell Line; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Hypnotics and Sedatives; Immunoassay; Muscle, Smooth, Vascular; Pentobarbital; Propofol; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Vasopressins | 2000 |
Effects of propofol, etomidate, and pentobarbital on critical oxygen delivery.
Topics: Anesthetics, Intravenous; Animals; Dogs; Dose-Response Relationship, Drug; Etomidate; Female; Hemodynamics; Lactates; Male; Oxygen Consumption; Pentobarbital; Propofol | 2000 |
Modulation of gamma-aminobutyric acid responses in the rat optic nerve.
Topics: Animals; Chlordiazepoxide; Dose-Response Relationship, Drug; Drug Synergism; Electrophysiology; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Optic Nerve; Pentobarbital; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2000 |
The effects of propofol in the area postrema of rats.
Topics: Anesthetics, Intravenous; Animals; Electric Stimulation; Electrophysiology; Fourth Ventricle; GABA-A Receptor Antagonists; Hypnotics and Sedatives; Immunohistochemistry; Male; Microelectrodes; Pentobarbital; Postoperative Nausea and Vomiting; Propofol; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Stereotaxic Techniques | 2001 |
Influence of membrane cholesterol on modulation of the GABA(A) receptor by neuroactive steroids and other potentiators.
Topics: Animals; Cell Membrane; Cholesterol; Dose-Response Relationship, Drug; Drug Synergism; Flunitrazepam; gamma-Aminobutyric Acid; Hippocampus; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Pentobarbital; Pregnanolone; Pregnenolone; Propofol; Rats; Rats, Wistar; Receptors, GABA-A | 2001 |
Anesthetic effects on mitochondrial ATP-sensitive K channel.
Topics: Adjuvants, Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; ATP-Binding Cassette Transporters; Decanoic Acids; Diazoxide; Diuretics; Dose-Response Relationship, Drug; Electron Transport; Flavoproteins; Guinea Pigs; Hydroxy Acids; In Vitro Techniques; Isoflurane; KATP Channels; Methyl Ethers; Mitochondria, Heart; Oxidation-Reduction; Pentobarbital; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Propofol; Sevoflurane; Sodium Chloride Symporter Inhibitors | 2001 |
Point mutation in the first transmembrane region of the beta 2 subunit of the gamma--aminobutyric acid type A receptor alters desensitization kinetics of gamma--aminobutyric acid- and anesthetic-induced channel gating.
Topics: Amino Acid Sequence; Anesthetics; Animals; Cells, Cultured; Electrophysiology; gamma-Aminobutyric Acid; Ion Channel Gating; Kinetics; Molecular Sequence Data; Pentobarbital; Point Mutation; Propofol; Rats; Receptors, GABA-A; Sequence Alignment; Spodoptera | 2002 |
Outcome of severe refractory status epilepticus in children.
Topics: Adolescent; Age Factors; Anesthetics, Intravenous; Anticonvulsants; Brain; Child; Child, Preschool; Drug Therapy, Combination; Electroencephalography; Female; Humans; Magnetic Resonance Imaging; Male; Midazolam; Outcome Assessment, Health Care; Pentobarbital; Propofol; Prospective Studies; Status Epilepticus; Treatment Outcome | 2001 |
Sleep-time variation for ethanol and the hypnotic drugs tribromoethanol, urethane, pentobarbital, and propofol within outbred ICR mice.
Topics: Animals; Crosses, Genetic; Ethanol; Female; Genetic Variation; Hypnotics and Sedatives; Male; Mice; Mice, Inbred ICR; Pentobarbital; Phenotype; Propofol; Sleep; Species Specificity; Time Factors; Urethane | 2002 |
The general anesthetic pentobarbital slows desensitization and deactivation of the glycine receptor in the rat spinal dorsal horn neurons.
Topics: Anesthetics, General; Animals; Etomidate; Neural Inhibition; Pentobarbital; Propofol; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Glycine; Spinal Cord; Taurine | 2002 |
Tolerability of bolus versus continuous gastric feeding in brain-injured patients.
Topics: Adjuvants, Anesthesia; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Ulcer Agents; Antiemetics; Brain Injuries; Cohort Studies; Critical Care; Enteral Nutrition; Female; Humans; Intubation, Gastrointestinal; Macrolides; Male; Middle Aged; Pentobarbital; Propofol; Retrospective Studies; Risk Factors; Severity of Illness Index; Stomach; Sucralfate | 2002 |
The effects of general anesthetics on norepinephrine release from isolated rat cortical nerve terminals.
Topics: Adjuvants, Anesthesia; Anesthetics, Dissociative; Anesthetics, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Cerebral Cortex; Egtazic Acid; Etomidate; Halothane; In Vitro Techniques; Ketamine; Nerve Endings; Norepinephrine; Pentobarbital; Potassium Chloride; Propofol; Rats; Receptors, Presynaptic; Synaptic Transmission; Synaptosomes | 2002 |
Spinal carbonic anhydrase contributes to nociceptive reflex enhancement by midazolam, pentobarbital, and propofol.
Topics: Acetazolamide; Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Ethoxzolamide; Hypnotics and Sedatives; Injections, Spinal; Male; Midazolam; Pain; Pain Measurement; Pentobarbital; Propofol; Rats; Rats, Sprague-Dawley; Reaction Time; Reflex; Spinal Cord | 2003 |
The inhibitory effects of ketamine and pentobarbital on substance p receptors expressed in Xenopus oocytes.
Topics: Aluminum Compounds; Anesthetics, Intravenous; Animals; Chloride Channels; Depression, Chemical; DNA, Complementary; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Fluorides; GABA Modulators; Indoles; Ketamine; Maleimides; Microinjections; Oocytes; Pentobarbital; Propofol; Protein Kinase C; Rats; Receptors, Neurokinin-1; Tramadol | 2003 |
A single M1 residue in the beta2 subunit alters channel gating of GABAA receptor in anesthetic modulation and direct activation.
Topics: Adjuvants, Anesthesia; Allosteric Site; Amino Acid Sequence; Anesthetics; Anesthetics, Intravenous; Animals; Cloning, Molecular; DNA Mutational Analysis; Dose-Response Relationship, Drug; Etomidate; Kinetics; Ligands; Models, Biological; Molecular Sequence Data; Mutagenesis; Mutation; Oocytes; Patch-Clamp Techniques; Pentobarbital; Point Mutation; Pregnanediones; Propofol; Protein Structure, Tertiary; Rats; Receptors, GABA-A; Recombinant Proteins; RNA, Messenger; Xenopus | 2003 |
Binary combinations of propofol and barbiturates on human alpha(1) glycine receptors expressed in Xenopus oocytes.
Topics: Anesthetics; Animals; Barbiturates; Drug Interactions; In Vitro Techniques; Methohexital; Microinjections; Oocytes; Patch-Clamp Techniques; Pentobarbital; Propofol; Receptors, Glycine; Thiopental; Xenopus laevis | 2003 |
Activity of chlormethiazole at human recombinant GABA(A) and NMDA receptors.
Topics: Animals; Chlormethiazole; DNA, Recombinant; Dose-Response Relationship, Drug; GABA Modulators; gamma-Aminobutyric Acid; Humans; Membrane Potentials; Oocytes; Pentobarbital; Propofol; Protein Subunits; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Xenopus laevis | 2003 |
Effects of propofol on respiratory mechanic and lung histology in normal rats.
Topics: Airway Resistance; Anesthetics, Intravenous; Animals; Female; Lung; Pentobarbital; Propofol; Rats; Rats, Wistar; Respiratory Mechanics | 2004 |
Now we lay them down to sleep: ethical issues with the use of pharmacologic coma for adult status epilepticus.
Topics: Adult; Anticonvulsants; Brain; Brain Edema; Coma; Drug Therapy; Fatal Outcome; Female; Humans; Hypnotics and Sedatives; Infarction, Middle Cerebral Artery; Intellectual Disability; Magnetic Resonance Imaging; Male; Middle Aged; Pentobarbital; Propofol; Status Epilepticus | 2004 |
Comparison of the effects of propofol and pentobarbital on left ventricular adaptation to an increased afterload.
Topics: Adaptation, Physiological; Animals; Aorta; Blood Pressure; Cardiac Output; Cardiac Volume; Elasticity; Female; Heart Rate; Infusions, Intravenous; Male; Pentobarbital; Propofol; Pulse; Stroke Volume; Swine; Vascular Resistance; Ventricular Function, Left | 2004 |
Contrasting anesthetic sensitivities of T-type Ca2+ channels of reticular thalamic neurons and recombinant Ca(v)3.3 channels.
Topics: Anesthetics, General; Barbiturates; Calcium Channel Blockers; Calcium Channels, T-Type; Cell Line; Dose-Response Relationship, Drug; Enflurane; Ethanol; Etomidate; Humans; Inhibitory Concentration 50; Isoflurane; Kinetics; Neurons, Afferent; Nitrous Oxide; Patch-Clamp Techniques; Pentobarbital; Propofol; Recombinant Proteins; Thalamus | 2005 |
Effect of N-methyl-D-aspartate receptor epsilon1 subunit gene disruption of the action of general anesthetic drugs in mice.
Topics: Anesthetics; Animals; Diazepam; Male; Methyl Ethers; Mice; Mice, Inbred C57BL; Mice, Knockout; Midazolam; Nitrous Oxide; Pentobarbital; Propofol; Receptors, N-Methyl-D-Aspartate; Sevoflurane | 2005 |
Ethyl 2-(4-bromophenyl)-1-(2,4-dichlorophenyl)-1H-4-imidazolecarboxylate is a novel positive modulator of GABAA receptors.
Topics: Animals; Binding, Competitive; Cell Membrane; Cerebral Cortex; Diazepam; Dose-Response Relationship, Drug; Etomidate; Female; Flunitrazepam; GABA Modulators; gamma-Aminobutyric Acid; Glycine; Humans; Hydrocarbons, Halogenated; Imidazoles; Male; Membrane Potentials; Oocytes; Pentobarbital; Pregnanediones; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Glycine; Receptors, Serotonin, 5-HT3; Serotonin; Tritium; Xenopus laevis | 2005 |
[Comparison of pentobarbital and propofol on the outcome of focal cerebral ischemia model in rats].
Topics: Adjuvants, Anesthesia; Anesthetics, Intravenous; Animals; Brain Ischemia; Disease Models, Animal; Infarction, Middle Cerebral Artery; Male; Pentobarbital; Propofol; Rats; Rats, Sprague-Dawley | 2004 |
Comparison of seven anesthetic agents on outcome after experimental traumatic brain injury in adult, male rats.
Topics: Anesthetics; Animals; Brain; Brain Injuries; Cell Survival; Cognition Disorders; Diazepam; Disease Models, Animal; Fentanyl; Hippocampus; Hypnotics and Sedatives; Isoflurane; Ketamine; Male; Morphine; Neuroprotective Agents; Pentobarbital; Propofol; Rats; Rats, Sprague-Dawley | 2006 |
Differential effects of intravenous anesthetics on ciliary motility in cultured rat tracheal epithelial cells.
Topics: Analgesics; Anesthetics, Intravenous; Animals; Cells, Cultured; Cilia; Dexmedetomidine; Epithelial Cells; Fentanyl; Hypnotics and Sedatives; In Vitro Techniques; Ketamine; Male; Midazolam; Motion; Pentobarbital; Propofol; Rats; Rats, Sprague-Dawley; Respiratory Mucosa; Thiopental; Time Factors; Trachea | 2006 |
Influence of external and intracellular pH on propofol-induced responses in rat locus coeruleus neurons.
Topics: Acidosis; Animals; Hydrogen-Ion Concentration; In Vitro Techniques; Locus Coeruleus; Male; Pentobarbital; Pregnanediones; Propofol; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2006 |
Sedation and anesthesia protocols used for magnetic resonance imaging studies in infants: provider and pharmacologic considerations.
Topics: Administration, Oral; Anesthesia, General; Anesthesiology; Anesthetics, Intravenous; Chloral Hydrate; Conscious Sedation; Humans; Hypnotics and Sedatives; Infant; Infusions, Intravenous; Magnetic Resonance Imaging; Nurse Anesthetists; Pentobarbital; Propofol; Retrospective Studies; Workforce | 2006 |
Supraspinal anesthesia: behavioral and electroencephalographic effects of intracerebroventricularly infused pentobarbital, propofol, fentanyl, and midazolam.
Topics: Anesthetics, Intravenous; Animals; Behavior, Animal; Brain; Consciousness; Data Interpretation, Statistical; Electric Stimulation; Electrodes, Implanted; Electroencephalography; Epilepsy; Fentanyl; Hypnotics and Sedatives; Injections, Intraventricular; Intracranial Pressure; Male; Midazolam; Pentobarbital; Propofol; Rats; Rats, Sprague-Dawley; Spinal Cord | 2006 |
Modulation of neuronal activity in CNS pain pathways following propofol administration in rats: Fos and EEG analysis.
Topics: Anesthesia; Anesthetics, Intravenous; Anesthetics, Local; Animals; Central Nervous System; Conscious Sedation; Electroencephalography; Functional Laterality; Genes, fos; Hypnotics and Sedatives; Immunohistochemistry; Infusions, Intravenous; Lidocaine; Neural Pathways; Neurons; Pain; Pentobarbital; Propofol; Rats | 2007 |
Inhibition of human 5-HT(3A) and 5-HT(3AB) receptors by etomidate, propofol and pentobarbital.
Topics: Animals; Dose-Response Relationship, Drug; Electrophysiology; Etomidate; Female; Humans; Hypnotics and Sedatives; Membrane Potentials; Microinjections; Oocytes; Pentobarbital; Propofol; Protein Isoforms; Receptors, Serotonin, 5-HT3; RNA; Xenopus laevis | 2007 |
[Effects of intravenous anesthetics on acidosis induced apoptosis in primary brain cell culture].
Topics: Acidosis; Anesthetics, Intravenous; Animals; Apoptosis; Brain; Calcium; Cells, Cultured; Female; Humans; Hydrogen-Ion Concentration; Male; Midazolam; Pentobarbital; Propofol; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar | 2007 |
Relevance of anaesthesia for dofetilide-induced torsades de pointes in alpha1-adrenoceptor-stimulated rabbits.
Topics: Anesthesia; Anesthetics; Animals; Anti-Inflammatory Agents; Baroreflex; Blood Pressure; Chloralose; Female; Heart Rate; Pentobarbital; Phenethylamines; Propofol; Rabbits; Receptors, Adrenergic, alpha-1; Sulfonamides; Sympathetic Nervous System; Torsades de Pointes; Vagus Nerve | 2008 |
Is propofol a safe alternative to pentobarbital for sedation during pediatric diagnostic CT?
Topics: Chi-Square Distribution; Child; Child, Preschool; Conscious Sedation; Female; Humans; Hypnotics and Sedatives; Linear Models; Male; Pentobarbital; Propofol; Prospective Studies; Statistics, Nonparametric; Tomography, X-Ray Computed | 2008 |
Menthol shares general anesthetic activity and sites of action on the GABA(A) receptor with the intravenous agent, propofol.
Topics: Anesthetics, General; Anesthetics, Intravenous; Animals; Cyclohexanols; Flumazenil; Flunitrazepam; Menthol; Pentobarbital; Pregnanolone; Propofol; Receptors, GABA-A; Xenopus | 2008 |
K+ channel TASK-1 knockout mice show enhanced sensitivities to ataxic and hypnotic effects of GABA(A) receptor ligands.
Topics: Animals; Anti-Anxiety Agents; Ataxia; Benzodiazepines; Brain; Diazepam; Female; Flurazepam; Hypnotics and Sedatives; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Nerve Tissue Proteins; Pentobarbital; Potassium Channels, Tandem Pore Domain; Propofol; Protein Kinase C; Receptors, GABA-A; Sex Factors; Spinal Cord | 2008 |
Drugs and brain death diagnostics: determination of drugs capable of inducing EEG zero line.
Topics: Anesthetics, Intravenous; Brain Death; Central Nervous System Depressants; Chromatography, High Pressure Liquid; Electroencephalography; Humans; Hypnotics and Sedatives; Methohexital; Pentobarbital; Propofol; Quality Control; Thiopental; Time Factors | 2008 |
Radiologists and anesthesiologists.
Topics: Anesthesia, Conduction; Anesthesia, General; Chloral Hydrate; Humans; Hypnotics and Sedatives; Magnetic Resonance Imaging; Pentobarbital; Practice Guidelines as Topic; Propofol; Radionuclide Imaging; Tomography, X-Ray Computed | 2009 |
Increased phosphorylation of extracellular signal-regulated kinase in trigeminal nociceptive neurons following propofol administration in rats.
Topics: Anesthetics, Local; Animals; Brain; Capsaicin; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Hypnotics and Sedatives; Lidocaine; Male; Nociceptors; Pentobarbital; Phosphorylation; Propofol; Rats; Rats, Sprague-Dawley; Sensory System Agents; Spinal Cord; Trigeminal Nerve | 2009 |
Pilocarpine model of temporal lobe epilepsy shows enhanced response to general anesthetics.
Topics: Anesthetics, General; Animals; Brain; Consciousness Disorders; Convulsants; Disease Models, Animal; Electroencephalography; Entorhinal Cortex; Epilepsy, Temporal Lobe; GABA Agonists; Halothane; Kindling, Neurologic; Male; Muscimol; Nerve Degeneration; Olfactory Pathways; Pentobarbital; Pilocarpine; Propofol; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2009 |
Propofol vs pentobarbital for sedation of children undergoing magnetic resonance imaging: results from the Pediatric Sedation Research Consortium.
Topics: Child; Child, Preschool; Cohort Studies; Conscious Sedation; Female; Humans; Hypnotics and Sedatives; Infant; Magnetic Resonance Imaging; Male; Midazolam; Pentobarbital; Practice Patterns, Physicians'; Propofol; Treatment Outcome | 2009 |
Status epilepticus.
Topics: Anticonvulsants; Benzodiazepines; Child; Clinical Protocols; Fructose; GABA Modulators; Humans; Ketamine; Levetiracetam; Midazolam; Pentobarbital; Phenobarbital; Phenytoin; Piracetam; Propofol; Status Epilepticus; Thiopental; Topiramate; Valproic Acid | 2011 |
Urethral catheterization of the female rat.
Topics: Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Female; Isoflurane; Pentobarbital; Propofol; Rats; Urinary Catheterization | 2011 |
Involvement of tuberomamillary histaminergic neurons in isoflurane anesthesia.
Topics: Anesthesia, Inhalation; Anesthetics, Dissociative; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Brain Chemistry; Histamine; Histamine Antagonists; Hypothalamus, Posterior; Immunohistochemistry; Injections, Intraventricular; Isoflurane; Ketamine; Male; Neurons; Orexin Receptors; Pentobarbital; Postural Balance; Propofol; Rats; Rats, Long-Evans; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Reflex; Ribosome Inactivating Proteins, Type 1; Saporins | 2011 |
Effects of propofol and pentobarbital on calcium concentration in presynaptic boutons on a rat hippocampal neuron.
Topics: Anesthetics; Animals; Calcium; GABA Modulators; Hippocampus; Neurons; Neurotransmitter Agents; Pentobarbital; Potassium; Presynaptic Terminals; Propofol; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission | 2011 |
Propofol protects against impairment of learning-memory and imbalance of hippocampal Glu/GABA induced by electroconvulsive shock in depressed rats.
Topics: Animals; Cognition; Depression; Down-Regulation; Electroconvulsive Therapy; Electroshock; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamates; Hippocampus; Learning; Male; Memory; Memory Disorders; Pentobarbital; Propofol; Rats; Rats, Sprague-Dawley; Seizures; Up-Regulation | 2011 |
The effect of alphaxalone-alphadolone, propofol, and pentobarbitone anaesthesia on the β-endorphin and ACTH response to haemorrhage in the pig.
Topics: Adrenocorticotropic Hormone; Anesthesia; Anesthetics; Animals; beta-Endorphin; Blood Pressure; Heart Rate; Hemorrhage; Hypovolemia; Pentobarbital; Pregnanediones; Propofol; Swine | 2011 |
The effect of pentobarbital sodium and propofol anesthesia on multifocal electroretinograms in rhesus macaques.
Topics: Anesthesia; Anesthetics, Intravenous; Animals; Electroretinography; Evoked Potentials, Visual; Female; Hypnotics and Sedatives; Macaca mulatta; Pentobarbital; Propofol; Retina; Retinoscopy; Signal-To-Noise Ratio | 2012 |
Successful treatment of permethrin toxicosis in two cats with an intravenous lipid administration.
Topics: Anesthetics, Intravenous; Animals; Anticonvulsants; Blood Cell Count; Blood Chemical Analysis; Cat Diseases; Cats; Diazepam; Fat Emulsions, Intravenous; Female; Hypnotics and Sedatives; Infusions, Intravenous; Insecticides; Isotonic Solutions; Male; Pentobarbital; Permethrin; Propofol; Ringer's Solution | 2012 |
Treatment of status epilepticus: an international survey of experts.
Topics: Administration, Intravenous; Adult; Anticonvulsants; Child; Consensus; Expert Testimony; Humans; Hypnotics and Sedatives; Levetiracetam; Lorazepam; Midazolam; Pentobarbital; Phenytoin; Piracetam; Propofol; Societies, Medical; Status Epilepticus; Surveys and Questionnaires; Valproic Acid | 2013 |
Anesthetic effects on susceptibility to cortical spreading depression.
Topics: Anesthetics; Animals; Cortical Spreading Depression; Dexmedetomidine; Isoflurane; Male; Pentobarbital; Propofol; Rats; Rats, Sprague-Dawley | 2013 |
Effects of general anesthetics on substance P release and c-Fos expression in the spinal dorsal horn.
Topics: Anesthetics, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Fentanyl; Hypnotics and Sedatives; Isoflurane; Male; Nitrous Oxide; Pentobarbital; Posterior Horn Cells; Propofol; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Sodium Chloride; Substance P | 2013 |
Effect of aquaporin-4 deficiency on intravenous anaesthetic induced hypnotic effects in mice.
Topics: Anesthetics, Intravenous; Animals; Aquaporin 4; Hypnotics and Sedatives; Ketamine; Mice; Mice, Knockout; Neurotransmitter Agents; Pentobarbital; Prefrontal Cortex; Propofol | 2013 |
The slow death of lethal injection.
Topics: Anesthetics, Intravenous; Capital Punishment; Humans; Hydromorphone; Injections, Intravenous; Midazolam; Pancuronium; Pentobarbital; Potassium Chloride; Propofol; Thiopental; United States | 2014 |
Effects of repetitive exposure to anesthetics and analgesics in the Tg2576 mouse Alzheimer's model.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analgesics; Anesthetics; Animals; CA1 Region, Hippocampal; Diazepam; Disease Models, Animal; Female; Frontal Lobe; Humans; Isoflurane; Ketamine; Male; Mice, Transgenic; Pentobarbital; Propofol; Spatial Navigation | 2014 |
Effects of propofol on electrocardiogram measures in mice.
Topics: Adjuvants, Anesthesia; Anesthesia; Anesthesia, Local; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Dose-Response Relationship, Drug; Electrocardiography; Heart Rate; Injections, Intraperitoneal; Isoflurane; Male; Mice, Inbred C57BL; Pentobarbital; Propofol | 2014 |
Predictive value of the bispectral index for burst suppression on diagnostic electroencephalogram during drug-induced coma.
Topics: Adult; Alcohol Withdrawal Seizures; Cerebral Cortex; Cohort Studies; Consciousness Monitors; Deep Sedation; Electroencephalography; Female; Humans; Infarction, Middle Cerebral Artery; Intensive Care Units; Male; Middle Aged; Pentobarbital; Predictive Value of Tests; Propofol; Prospective Studies; Psychotic Disorders; Signal Processing, Computer-Assisted; Statistics as Topic; Status Epilepticus | 2015 |
Synaptic-type α1β2γ2L GABAA receptors produce large persistent currents in the presence of ambient GABA and anesthetic drugs.
Topics: Anesthetics; Animals; Cell Line; Chromosome Pairing; Etomidate; gamma-Aminobutyric Acid; HEK293 Cells; Humans; Pentobarbital; Pregnanediones; Propofol; Rats; Receptors, GABA-A | 2015 |
Differential effects of general anesthetics on anxiety-like behavior in formalin-induced pain: involvement of ERK activation in the anterior cingulate cortex.
Topics: Anesthetics, Inhalation; Animals; Anxiety; Behavior, Animal; Extracellular Signal-Regulated MAP Kinases; Formaldehyde; Gyrus Cinguli; Male; Methyl Ethers; Pain; Pain Measurement; Pentobarbital; Propofol; Rats; Rats, Sprague-Dawley; Sevoflurane; Spinal Cord | 2015 |
Functional sites involved in modulation of the GABAA receptor channel by the intravenous anesthetics propofol, etomidate and pentobarbital.
Topics: Anesthetics, Intravenous; Animals; Binding Sites; Electrophysiological Phenomena; Etomidate; Mutation; Oocytes; Pentobarbital; Propofol; Rats; Receptors, GABA-A; Xenopus | 2016 |
Acute effects of general anesthesia with propofol, pentobarbital or isoflurane plus propofol on plasma metabolites and hormones in adult pigs.
Topics: Anesthesia, General; Anesthetics; Animals; Azaperone; Blood Glucose; Female; Hydrocortisone; Hypnotics and Sedatives; Insulin; Isoflurane; Ketamine; Pentobarbital; Propofol; Swine; Xylazine | 2016 |
Functional sites for anesthetics in GABAA receptors.
Topics: Allosteric Site; Anesthetics; Animals; Binding Sites; DNA Mutational Analysis; Etomidate; Humans; Ions; Mutation; Neurotransmitter Agents; Oocytes; Pentobarbital; Propofol; Protein Domains; Protein Isoforms; Receptors, GABA-A; Xenopus | 2017 |
A chimeric prokaryotic-eukaryotic pentameric ligand gated ion channel reveals interactions between the extracellular and transmembrane domains shape neurosteroid modulation.
Topics: Animals; Bacterial Proteins; Cell Membrane; Chlorides; Etomidate; Extracellular Space; gamma-Aminobutyric Acid; Humans; Ligand-Gated Ion Channels; Membrane Potentials; Mutation; Neurotransmitter Agents; Oocytes; Pentobarbital; Picrotoxin; Propofol; Protein Domains; Protons; Receptors, GABA-B; Recombinant Fusion Proteins; Xenopus laevis | 2017 |
Activation of Endocannabinoid Receptor 2 as a Mechanism of Propofol Pretreatment-Induced Cardioprotection against Ischemia-Reperfusion Injury in Rats.
Topics: Animals; Apoptosis; Arachidonic Acids; Benzamides; Carbamates; Cells, Cultured; Endocannabinoids; Indoles; Male; Malondialdehyde; Myocardial Reperfusion Injury; Myocytes, Cardiac; Pentobarbital; Peroxidase; Propofol; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Signal Transduction; Superoxide Dismutase | 2017 |
Impact of Anesthetic Regimen on Remote Ischemic Preconditioning in the Rat Heart In Vivo.
Topics: Analgesics, Opioid; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Disease Models, Animal; Hypnotics and Sedatives; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Pentobarbital; Propofol; Rats, Wistar; Remifentanil; Sevoflurane; Time Factors | 2018 |
GABA Type A Receptor Activation in the Allosteric Coagonist Model Framework: Relationship between EC
Topics: Allosteric Regulation; Anesthetics; Animals; Binding Sites; Dose-Response Relationship, Drug; Drug Interactions; GABA Agonists; gamma-Aminobutyric Acid; Models, Biological; Models, Theoretical; Mutation; Oocytes; Patch-Clamp Techniques; Pentobarbital; Pregnanediones; Propofol; Receptors, GABA-A; Xenopus laevis | 2018 |
Comparison of pentobarbital-phenytoin alone vs propofol prior to pentobarbital-phenytoin for euthanasia in 436 client-owned dogs.
Topics: Anesthetics, Intravenous; Animals; Dogs; Drug Therapy, Combination; Euthanasia, Animal; Female; Incidence; Male; Pentobarbital; Phenytoin; Propofol; Prospective Studies; Spasm; Texas | 2019 |
Steady-State Activation and Modulation of the Concatemeric
Topics: Allosteric Regulation; Animals; beta-Alanine; GABA-A Receptor Agonists; Multiprotein Complexes; Pentobarbital; Pregnanolone; Propofol; Receptors, GABA-A; Xenopus laevis | 2019 |
Different anaesthesia methods affect the development of hepatoblastoma after platelet activation.
Topics: Animals; Hepatoblastoma; Hypnotics and Sedatives; Liver Neoplasms; Pentobarbital; Platelet Activation; Propofol; Rabbits; Signal Transduction | 2021 |
Activation of the Rat α1β2ε GABA
Topics: Animals; Cysteine; gamma-Aminobutyric Acid; Pentobarbital; Propofol; Rats; Receptors, GABA-A | 2022 |
Inhibition of mitochondrial respiration by general anesthetic drugs.
Topics: Adenosine Triphosphate; Anesthetics, General; Animals; Electron Transport Complex I; Halothane; Isoflurane; Ketamine; Mice; Mitochondria; Pentobarbital; Propofol | 2023 |