pentobarbital has been researched along with gamma-aminobutyric acid in 469 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 219 (46.70) | 18.7374 |
| 1990's | 140 (29.85) | 18.2507 |
| 2000's | 76 (16.20) | 29.6817 |
| 2010's | 26 (5.54) | 24.3611 |
| 2020's | 8 (1.71) | 2.80 |
| Authors | Studies |
|---|---|
| Berl, S; Nicklas, WJ; Weinberger, J | 1 |
| Nicoll, RA | 4 |
| Blanc-Bimar, MC; Bouyard, P; Bruguerolle, B; Jadot, G; Valli, M | 1 |
| Duggan, AW; Headley, PM; Lodge, D | 1 |
| Dinnedahl, V; Gumulka, SW; Opmeer, FA; Schönhöfer, PS | 1 |
| Bowery, NG; Dray, A | 1 |
| Barker, JL; Macdonald, RL | 2 |
| Evans, RH | 3 |
| Adey, WR; Kaczmarek, LK | 1 |
| Cotman, CW; Haycock, JW; Levy, WB | 1 |
| Cutler, RW; Young, J | 1 |
| Bauer, B | 2 |
| Aickin, CC; Deisz, RA | 2 |
| Franco, S; Schlosser, W | 1 |
| Sastry, BR | 1 |
| Alger, BE; Nicoll, RA | 4 |
| Chase, TN; Pericić, D; Walters, JR | 1 |
| Curtis, DR; Lodge, D | 2 |
| Osuide, G; Sokomba, EN | 1 |
| Fukushima, H; Tsuchiya, T | 1 |
| Fujimoto, S; Hisada, S | 1 |
| Barker, JL; Ransom, BR | 3 |
| Hertz, L; Sastry, BR | 1 |
| Coleman-Riese, D; Cutler, RW | 1 |
| Hitzemann, RJ; Loh, HH | 1 |
| Ondo, JG; Pass, KA | 1 |
| Ho, IK; Tzeng, S | 1 |
| Jessell, TM; Richards, CD | 1 |
| Chuppina, LM | 1 |
| Gusel'nikova, KG; Ivanova, LV; Kipor, GV | 1 |
| Cutler, RW; Dudzinski, DS | 2 |
| Dye, DJ; Taberner, PV | 1 |
| Barker, JL | 3 |
| Headley, PM; Lodge, D | 1 |
| Liu, CC; Nichols, AC; Snead, OC | 1 |
| Brioni, JD; Córdoba, NE; Cuadra, GR; Orsingher, OA | 1 |
| Prince, RJ; Simmonds, MA | 1 |
| Bertrand, PP; Galligan, JJ | 1 |
| Amatsu, M; Nishimura, S; Okada, Y | 1 |
| Atkinson, AE; Barnard, EA; Beadle, DJ; Bermudez, I; Darlison, MG; Earley, FG; King, LA; Possee, RD | 1 |
| Mihic, SJ; Nguyen, T; O'Dowd, BF; Van Berckel, BN; Wu, PH | 1 |
| Hadingham, KL; Horne, AL; Kemp, JA; Macaulay, AJ; Whiting, P | 1 |
| Berger, T; Kettenmann, H; Schnitzer, J; Walz, W | 1 |
| Biggio, G; Concas, A; Maciocco, E; Mascia, MP; Santoro, G | 1 |
| Arakawa, O; Nakahiro, M; Narahashi, T | 1 |
| Melchior, CL; Ritzmann, RF | 1 |
| Ishibashi, S; Ishii, K; Okazaki, H; Tokuda, H | 1 |
| Aibara, K; Akaike, N; Itabashi, S; Sasaki, H | 1 |
| Ashton, D; Willems, R | 1 |
| Allan, AM; Draski, LJ; Mayes, GG | 1 |
| Long, SK; van Wilgenburg, H; Wesselman, JP | 1 |
| Gee, KW; Lan, NC | 1 |
| Gautam, SK; Kulkarni, SK | 1 |
| Asprodini, EK; Rainnie, DG; Shinnick-Gallagher, P | 1 |
| Harris, RA; McQuilkin, SJ | 1 |
| Chernevskaia, NI; Kryshtal', OA; Valeev, AE | 1 |
| Farb, DH; Friedman, L; Gibbs, TT; Roca, DJ; Rozenberg, I; Schiller, GD | 1 |
| Kaneko, A; Suzuki, S; Tachibana, M | 1 |
| Dohi, T; Kitayama, S; Morita, K; Tsujimoto, A | 1 |
| Baur, R; Malherbe, P; Möhler, H; Sigel, E; Trube, G | 1 |
| Miledi, R; Polenzani, L; Woodward, RM | 1 |
| Akaike, N; Shirasaki, T; Yakushiji, T | 1 |
| Kalant, H; Mihic, SJ; Wu, PH | 2 |
| Kalant, H; Marchese, A; Mihic, SJ; Wu, PH | 1 |
| Ben-Ari, Y; Rovira, C | 1 |
| McIntyre, T; Skolnick, P | 1 |
| Cano, J; Machado, A; Ruano, D; Vitorica, J | 1 |
| Blakeman, DP; Im, WB | 1 |
| Spyer, KM; Sun, MK | 1 |
| MacIver, MB; Mody, I; Tanelian, DL | 2 |
| Boeijinga, PH; Lopes da Silva, FH; Pennartz, CM | 1 |
| Akaike, N; Nakagawa, T; Nakaye, T; Shirasaki, T; Wakamori, M | 1 |
| Hsiao, CF; Huang, C; Huang, R; Liu, G | 1 |
| Getova, D | 1 |
| Ayer, DE; Blakeman, DP; Davis, JP; Im, WB | 1 |
| Delaney, T; Friedman, R; Oldfield, EH; Olson, JJ; Orr, K | 1 |
| Costa, E; Paul, SM; Pritchett, DB; Puia, G; Purdy, RH; Santi, MR; Seeburg, PH; Vicini, S | 1 |
| Baur, R; Malherbe, P; Mohler, H; Persohn, E; Richards, JG; Sigel, E | 1 |
| Ferrendelli, JA; Miller, JW | 1 |
| White, G | 1 |
| Friedman, DL; Redburn, DA | 1 |
| Kim, KH; Takeuchi, H | 1 |
| Biggio, G; Concas, A; Mascia, MP; Sanna, E; Santoro, G; Serra, M | 1 |
| Akaike, N; Ikemoto, Y; Tokutomi, N | 1 |
| Osmanović, SS; Shefner, SA | 1 |
| González, JM; Martínez-Luque, M; Muñoz-Blanco, J; Yusta, B | 1 |
| Dingledine, R; Korn, SJ | 1 |
| Mathers, DA | 2 |
| Akaike, N; Oomura, Y | 1 |
| Kita, H; Kita, T; Kitai, ST | 1 |
| Akaike, N | 1 |
| Allan, AM; Harris, RA | 2 |
| Paul, SM; Schwartz, RD; Suzdak, PD | 1 |
| Akaike, N; Hattori, K; Oomura, Y | 1 |
| Bourque, CW; Randle, JC; Renaud, LP | 1 |
| Chernevskaia, NI; Valeev, AE; Vrublevskiĭ, SV | 1 |
| Smith, GK; Suzuki, SS | 1 |
| Macdonald, RL; Rogers, CJ; Twyman, RE; Weddle, MG | 1 |
| Atsoggiu, T; Biggio, G; Concas, A; Pepitoni, S; Toffano, G | 1 |
| Akaike, N; Ikemoto, Y; Kijima, H | 1 |
| Robertson, B | 1 |
| Valeev, AE | 1 |
| Dudek, BC; Phillips, TJ | 1 |
| Baur, R; Peter, AB; Sigel, E; Yao, Y | 1 |
| Abel, MS; Blume, AJ; Garrett, KM | 1 |
| Iwasaki, M | 1 |
| Holden-Dye, L; Krogsgaard-Larsen, P; Nielsen, L; Walker, RJ | 1 |
| Bédard, L; Roberge, AG; Seoane, JR; Thibault, L; Wandji, SA | 1 |
| Brown, MC; Lunt, GC; Stapleton, A | 1 |
| Starr, BS; Starr, MS | 1 |
| Akaike, N; Hattori, K; Inomata, N; Oomura, Y | 1 |
| Culp, S; Liljequist, S; Tabakoff, B | 2 |
| Akaike, N; Oyama, Y; Yakushiji, T | 1 |
| Nistri, A; Sivilotti, L | 1 |
| Sykes, TC; Thomson, AM | 1 |
| Bristow, DR; Martin, IL | 1 |
| Mehta, AK; Ticku, MK | 1 |
| Barnett, A; Biggio, G; Corda, MG; Giorgi, O; Longoni, B; Montaldo, S; Ongini, E | 1 |
| Karanian, JW; Morrow, AL; Paul, SM; Suzdak, PD | 1 |
| Gale, RG; Little, HJ; Nutt, DJ; Standing, BL; Taylor, SC | 1 |
| Hara, S; Morioka, S; Satoh, K; Yanagihara, S | 1 |
| Georgiev, V; Getova, D | 1 |
| Backus, KH; Kettenmann, H; Schachner, M | 1 |
| Leidenheimer, NJ; Schechter, MD | 1 |
| Harris, C; Lal, H | 1 |
| Blaxter, TJ; Carlen, PL; Davies, MF; Gurevich, N; O'Beirne, M | 1 |
| Alpern, HP; McIntyre, TD | 1 |
| Eysel, UT; Pape, HC; Van Schayck, R | 1 |
| Handley, SL; Heaton, JC; Rea, PJ; Singh, L | 1 |
| Gross, RA; Macdonald, RL; Weddle, MG | 1 |
| Gundersen, CB; Miledi, R; Parker, I | 1 |
| Duce, IR; Scott, RH | 1 |
| McGarrick, JD; Stone, TW; Thexton, AJ | 1 |
| Biggio, G; Concas, A; Corda, MG; Serra, M | 1 |
| Iwai, S; Shirakawa, J; Tanaka, C; Taniyama, K | 1 |
| Deutsch, SI; Greenblatt, DJ; Miller, LG; Paul, SM; Shader, RI | 1 |
| Assaf, HM; Lust, WD; Ratcheson, RA; Ricci, AJ; Sternau, LL | 1 |
| Bielik, P; Pavlásek, J | 1 |
| Fanelli, RJ; Iadarola, MJ; McNamara, JO; Wilson, WA | 1 |
| Olsen, RW; Snowman, AM | 1 |
| Rastogi, SK; Ticku, MK | 2 |
| Sarvey, JM; Scharfman, HE | 1 |
| Ohmura, Y | 1 |
| Scholfield, CN; Steel, L | 1 |
| Chweh, AY; Swinyard, EA; Ulloque, RA; Wolf, HH | 1 |
| Komiskey, HL; Meyers, MB | 1 |
| Cohen, RM; Havoundjian, H; Paul, SM; Skolnick, P | 1 |
| Sweetnam, PM; Tallman, JF | 1 |
| Kerr, DI; Ong, J; Prager, RH; Ward, DA | 1 |
| Garcha, HS; Rose, IC; Stolerman, IP | 1 |
| Audi, EA; Brandão, ML; Graeff, FG; Schütz, MT | 1 |
| Little, HJ; Nutt, DJ; Taylor, SC | 1 |
| Maksay, G; Nielsen, M; Simonyi, M | 1 |
| Beadle, DJ; Benson, JA; Lees, G; Neumann, R | 1 |
| Liebeskind, JC; Morgan, MM; Stein, C | 1 |
| Lindgren, S; Simmonds, MA | 1 |
| Olsen, RW; Yang, JS | 1 |
| Dworkin, SI; Miyauchi, T; Smith, JE | 1 |
| Dhawan, BN; Gulati, A; Singh, HK; Srimal, RC | 1 |
| Majewska, MD; Mienville, JM; Vicini, S | 1 |
| Bédard, L; Caron, N; Seoane, JR | 1 |
| Lee, M; Netzeband, JG; Strahlendorf, HK; Strahlendorf, JC | 1 |
| Co, C; Dworkin, SI; Miyauchi, T; Smith, JE | 1 |
| Beshears, JF; Commissaris, RL; Halas, NA; McCloskey, TC | 1 |
| Chiu, TH; Rosenberg, HC; Yu, OF | 1 |
| Erdö, SL; Maksay, G | 1 |
| Lin, WC; Watanabe, K; Yano, S | 1 |
| Akaike, N; Maruyama, T; Tokutomi, N | 1 |
| Covey, DF; Ferrendelli, JA; Levine, JA; Naritoku, DK | 1 |
| Biggio, G; Concas, A; Mele, S | 1 |
| Boudinot, E; Champagnat, J; Denavit-Saubié, M; Foutz, AS; Gonsalves, SF; Morin-Surun, MP | 1 |
| Rock, DM; Taylor, CP | 1 |
| Dunwiddie, TV; Olsen, RW; Worth, TS | 1 |
| Oertel, D; Wu, SH | 1 |
| Little, HJ; Thomas, DL | 1 |
| Palermo-Neto, J; Sandoval, MR | 1 |
| Dunwiddie, TV; Mynlieff, M; Proctor, WR | 1 |
| Girard, CL; Matte, JJ; Seoane, JR | 1 |
| Lux, HD | 1 |
| Cutler, RW; Dudzinski, DS; Markowitz, D | 1 |
| Batuev, AS | 1 |
| Dhumal, VR; Gulati, OD; Raghunath, PR; Sivaramakrishna, N | 1 |
| Simmonds, MA; Sutton, I | 1 |
| Ramanjaneyulu, R; Ticku, MK | 2 |
| Jackson, MB | 1 |
| Hablitz, JJ; Weiss, DS | 1 |
| Kamp, CW; Morgan, WW | 1 |
| Cote, IL; Wilson, WA | 1 |
| Richter, JA; Waller, MB | 1 |
| Gibb, JW; Hotchkiss, A | 1 |
| Marangos, PJ; Paul, SM; Skolnick, P | 1 |
| Goodwin, FK; Marangos, PJ; Paul, SM; Skolnick, P | 1 |
| Barker, JL; Mathers, DA | 2 |
| Chiu, TH; Rosenberg, HC | 1 |
| Curtis, DR; Johnston, GA; Peet, MJ; Willow, M | 1 |
| Harris, RA; Rohde, BH | 2 |
| Cardinali, DP; Lowenstein, PR | 1 |
| Barker, JL; Segal, M | 1 |
| Thomson, AM; Vlachonikolis, IG; West, DC | 1 |
| Nicoll, RA; Wojtowicz, JM | 1 |
| Barker, JL; Paul, SM; Skolnick, P | 1 |
| Barker, JL; Moncada, V; Paul, SM; Skolnick, P | 1 |
| Connors, BW | 1 |
| Macdonald, RL; Schulz, DW | 1 |
| Johnston, GA; Willow, M | 3 |
| Willow, M | 1 |
| Asano, T; Ogasawara, N | 1 |
| Fanelli, RJ; McNamara, JO; Valdes, F | 1 |
| Barker, JL; Study, RE | 1 |
| Ho, IK; Nabeshima, T; Sivam, SP | 1 |
| Horst, WD; Kuhar, MJ; Mashal, RD; Niehoff, DL; O'Brien, RA; Palacios, JM | 1 |
| Barker, JL; Jackson, MB; Lecar, H; Mathers, DA | 1 |
| DeHaven, R; Pong, SS; Wang, CC | 1 |
| Turner, AJ; Whittle, SR | 1 |
| Fukuda, H; Matsumoto, K | 1 |
| Higashi, H; Nishi, S | 1 |
| Leeb-Lundberg, LM; Olsen, RW | 1 |
| Ebel, C; Mallorga, P; Roth-Schechter, BF | 2 |
| Fanelli, RJ; McNamara, JO | 1 |
| Ramanjaneyulu, R; Thyagarajan, R; Ticku, MK | 1 |
| DiMicco, JA; Gillis, RA; Hamosh, P; Norman, WP; Segal, SA; Williford, DJ; Yamada, KA | 1 |
| Andrews, PR; Johnston, GA; Katsikas, T; Nicholson, GM; Skerritt, JH; Tabar, J | 1 |
| Ticku, MK | 1 |
| Barnard, EA; Sigel, E | 1 |
| Leeb-Lundberg, LM; Olsen, RW; Teichberg, VI; Wong, EH | 1 |
| Herling, S; Valentino, RJ; Winger, GD | 1 |
| Gillis, RA; Hamosh, P; Moerschbaecher, JM; Yamada, KA | 1 |
| Hertz, L; Krogsgaard-Larsen, P; Larsson, OM; Schousboe, A | 1 |
| Cullen, KD; Martin, RJ | 1 |
| Macdonald, RL; McLean, MJ | 1 |
| Blume, WT; Bolton, CF; Warren, KG; Young, GB | 1 |
| Boudinot, E; Champagnat, J; Denavit-Saubié, M; Moyanova, S; Rondouin, G | 1 |
| Desarmenien, M; Feltz, P; Headley, PM; Santangelo, F | 1 |
| Burnham, WM; Kalichman, MW; Livingston, KE | 1 |
| Mayer, ML | 2 |
| Carrer, HF; Ferreyra, H | 1 |
| Collins, GG | 2 |
| Amin, J; Weiss, DS | 1 |
| Nabeshima, A; Saito, T; Takahata, N | 1 |
| Nabeshima, A; Saito, T; Takahata, N; Toki, S | 1 |
| Barker, JL; Dunlap, VS; Valeyev, AY | 1 |
| Dartois, E; Fillion, G; Haour, F; Moyse, E; Vincens, M | 1 |
| Bormann, J; Feigenspan, A; Wässle, H | 1 |
| Ma, JY; Narahashi, T | 1 |
| Peoples, RW; Weight, FF | 1 |
| Garau, F; Harris, RA; Sanna, E | 1 |
| Griffith, WH; Murchison, DA | 1 |
| Bähring, R; Grantyn, R; Martelli, EA; Standhardt, H | 1 |
| Blackmore, PF; Bleasdale, JE; Im, WB | 1 |
| Belelli, D; Chen, R; Lambert, JJ; Lan, NC; Peters, JA; Reyes, A | 1 |
| Biggio, G; Concas, A; Dazzi, L; Maciocco, E; Mascia, MP; Santoro, G | 1 |
| Barker, JL; ffrench-Mullen, JM; Rogawski, MA | 1 |
| Lukasiewicz, PD; Maple, BR; Werblin, FS | 1 |
| Bain, CJ; Kemp, JA; McKernan, RM; Quirk, K; Wafford, KA; Whiting, PJ; Wingrove, PB | 1 |
| Nagata, K; Narahashi, T | 1 |
| Fincher, AS; Frye, GD; Griffith, WH; Grover, CA | 1 |
| Gitter, AH; Möhler, H; Plinkert, PK; Zenner, HP | 1 |
| Alastra, AJ; Cohen, C; Goldberg, SR; Marley, RJ; Sannerud, CA; Serdikoff, SL | 1 |
| Aguayo, LG; Alarcón, JM | 1 |
| Kalant, H; Mihic, SJ; van Berckel, BN; Wu, PH | 1 |
| Hadingham, KL; Harkness, PC; Horne, AL; Kemp, JA; Whiting, P | 1 |
| Smart, TG; Xie, X | 1 |
| Barker, JL; Cruciani, RA; Lange, GD; Mahan, LC; Smallwood, VV; Valeyev, AY | 1 |
| Carlen, PL; Weiner, JL; Zhang, L | 1 |
| Misawa, M; Motegi, H; Suzuki, T | 1 |
| Dowling, JE; Qian, H | 1 |
| Ticku, MK; Yu, R | 1 |
| Fuchs, K; Sieghart, W; Slany, A; Zezula, J | 1 |
| Krůsek, J; Vanĕcek, J; Zemková, H | 1 |
| Chang, YF; Gao, XM | 1 |
| Biggio, G; Ghiani, CA; Maciocco, E; Sanna, E; Serra, M; Tuligi, G | 1 |
| Bain, C; Garrett, EM; Hadingham, KL; Heavens, RP; Sirinathsinghji, DJ; Wafford, KA; Whiting, PJ | 1 |
| Krishek, BJ; Moss, SJ; Smart, TG | 1 |
| Macdonald, RL; Saxena, NC | 1 |
| Nakashima, K; Todd, MM | 1 |
| Belelli, D; Callachan, H; Hill-Venning, C; Lambert, JJ; Peters, JA | 1 |
| Fiszer de Plazas, S; Mitridate de Novara, A; Viapiano, MS | 1 |
| Harris, CL; Quinn, MR | 1 |
| George, B; Kulkarni, SK | 1 |
| Thompson, SA; Wafford, KA; Whiting, PJ | 1 |
| Cestari, IN; Uchida, I; Yang, J | 1 |
| Akaike, N; Harata, N; Wu, J | 1 |
| Donevan, SD; Rho, JM; Rogawski, MA | 1 |
| Bracamontes, J; Steinbach, JH; Ueno, S; Weiss, DS; Zorumski, C | 1 |
| Davies, PA; Hales, TG; Hanna, MC; Kirkness, EF | 1 |
| Birnir, B; Cox, GB; Dalziel, JE; Gage, PW; Tierney, ML | 1 |
| Belachew, S; Coucke, P; Goffin, F; Lefebvre, PP; Malgrange, B; Moonen, G; Rigo, JM; Van de Water, TR; Xhauflaire, G | 1 |
| Davies, PA; Hales, TG; Kirkness, EF | 1 |
| Feltz, P; Poisbeau, P; Schlichter, R | 1 |
| Akaike, N; Imanishi, T; Xu, TL | 1 |
| Castel, H; Cazin, L; Le Foll, F; Louiset, E; Vaudry, H | 1 |
| Aimi, N; Leewanich, P; Matsumoto, K; Subhadhirasakul, S; Takayama, H; Tohda, M; Watanabe, H | 1 |
| Aspinwall, LS; Bermudez, I; King, LA; Wafford, KA | 1 |
| Kaila, K; Lamsa, K | 1 |
| Fisher, JL; Macdonald, RL; Zhang, J | 1 |
| Bundy, GL; Carter, DB; Im, HK; Im, WB; Schwartz, TM; VonVoigtlander, PF | 1 |
| Li, TK; Lumeng, L; McBride, WJ; Thielen, RJ | 1 |
| Boothe, DM | 1 |
| Greenfield, LJ; Macdonald, RL; Neelands, TR; Turner, RS; Zhang, J | 1 |
| Huang, Y; Lu, L | 1 |
| Heal, DJ; Martin, KF; Phillips, I; Thompson, KS | 1 |
| Borghese, CM; Córdoba, NE; Laino, CH; Niselman, V; Orsingher, OA; Rubio, MC | 1 |
| Dunwiddie, TV; Proctor, WR; Soldo, BL | 1 |
| Alvarez-Hernandez, X; Bueno, OF; Leidenheimer, NJ; Robinson, LC | 1 |
| Banerjee, PK; Brailowsky, S; Olsen, RW; Snead, OC; Tillakaratne, NJ; Tobin, AJ | 1 |
| Korpi, ER; Maksay, G; Uusi-Oukari, M | 1 |
| Bianchi, M; Fisher, JL; Macdonald, RL; Neelands, TR | 1 |
| Belelli, D; Lambert, JJ; McGurk, K; Peters, JA; Pistis, M | 1 |
| Baekkeskov, S; Hodge, C; Kash, SF; Tecott, LH | 1 |
| Amin, J | 1 |
| Fukami, S; Mashimo, T; Takenoshita, M; Uchida, I; Yoshiya, I | 1 |
| Hu, HZ; Li, ZW; Shao, M | 1 |
| Cupello, A; Hydén, H; Rapallino, MV | 1 |
| Chau, C; Hales, TG; Kaufman, DL; Tian, J | 1 |
| Colado, MI; Esteban, B; Granados, R; Green, AR; O'Shea, E | 1 |
| Chaudhuri, AK; Pal, S; Sen, T | 1 |
| Hu, GY; Li, JS; Pang, ZP; Xu, TL | 1 |
| Belelli, D; Lambert, JJ; Peters, JA; Pistis, M | 1 |
| Davidoff, RA; Hackman, JC; Holohean, AM; Katz, JL; Valeyev, AY; Wood, PM | 1 |
| Belelli, D; Cabras, G; Lambert, JJ; Pau, D; Peters, JA | 1 |
| Chebib, M; Cordato, DJ; Herkes, GK; Johnston, GA; Mather, LE | 1 |
| Fiszer de Plazas, S; Mitridate de Novara, AM; Rodríguez Gil, DJ; Viapiano, MS | 1 |
| Birnir, B; Cox, GB; Dalziel, JE; Gage, PW | 1 |
| Chen, CL; Chiu, TH; Yang, YR | 1 |
| Connolly, CN; Gorrie, GH; Hosie, A; Kittler, JT; Moss, SJ; Smart, TG; Taylor, PM | 1 |
| Carlson, BX; Engblom, AC; Kristiansen, U; Olsen, RW; Schousboe, A | 2 |
| Brückner, C; Heinemann, U | 1 |
| Galligan, JJ; Zhou, X | 1 |
| Bracamontes, J; Serafini, R; Steinbach, JH | 1 |
| Sapp, DW; Yeh, HH | 1 |
| Green, AR; Hainsworth, AH; Lambert, DG; Nelson, RM | 1 |
| Chopde, CT; Deshmukh, VK; Kasture, VS | 2 |
| Empson, RM; Newberry, NR; Sheardown, MJ | 1 |
| Birnir, B; Eghbali, M; Gage, PW | 2 |
| Saxena, NC | 1 |
| Dekermendjian, K; Hartvig, L; Liljefors, T; Lükensmejer, B | 1 |
| Dreyfus, H; Jellali, A; Pattnaik, B; Picaud, S; Sahel, J | 1 |
| Birnir, B; Eghbali, M; Everitt, AB; Gage, PW | 1 |
| Findlay, GS; Harris, RA; Harrison, NL; Ueno, S | 1 |
| Fiszer de Plazas, S; Rodríguez Gil, DJ; Viapiano, MS | 1 |
| Lambert, JJ; Nicholls, DG; Rego, AC | 1 |
| Akk, G; Bracamontes, J; Steinbach, JH | 2 |
| Benson, JA; Darlison, MG; Forster, IC; Harvey, RJ | 1 |
| Arenas, E; Canals, JM; Ernfors, P; Naveilhan, P; Valjakka, A; Vartiainen, J | 1 |
| Adkins, CE; Bonnert, TP; Gonzalez, JE; Haldon, C; Kerby, J; McKernan, RM; Oades, K; Pillai, GV; Simpson, PB; Whiting, PJ | 1 |
| Aoyagi, Y; Ohta, A; Watanabe, Y; Yamada, K | 1 |
| Bossert, JM; Franklin, KB | 2 |
| Avossa, D; Ballerini, L; Galante, M; Rosato-Siri, M | 1 |
| Boscan, P; Davies, KA; Garret, M; Kasparov, S; Patel, UA; Paton, JF | 1 |
| Simmonds, MA; Sooksawate, T | 1 |
| Akk, G; Steinbach, JH | 1 |
| Basilico, C; Korada, S; Schwartz, ML; Vaccarino, FM; Zheng, W | 1 |
| Fisher, JL | 1 |
| Andresen, MC; Chang, KS; Evans, C; Hales, TG; Irnaten, M; Mendelowitz, D; Venkatesan, P; Walwyn, WM; Wang, J | 1 |
| Chan, P; Ellsworth, K; Partridge, LD; Schroeder, KM; Wu, J | 1 |
| Bonnert, TP; Cagetti, E; Thompson, SA; Wafford, KA; Whiting, PJ | 1 |
| Kullmann, DM; Semyanov, A | 1 |
| Menzikov, S; Menzikova, O | 1 |
| Czajkowski, C; Newell, JG | 1 |
| Holmes, GL; Khazipov, R | 1 |
| Bäckström, T; Lundgren, P; Strömberg, J; Wang, M | 1 |
| Andreatta-Van Leyen, S; Araujo, GC; Campos, RR; Guertzenstein, PG; Lacerda, JE; Lopes, OU | 1 |
| BALAGOT, RC; SADOVE, MS; TSUJI, H | 1 |
| BHARGAVA, KP; BHATTACHARYA, SS; KISHOR, K; SAXENA, PN | 1 |
| ROBERTS, E; SCHOLES, NW | 1 |
| BERNHEIM, F; NAKAMURA, K | 1 |
| Thompson, SA; Usala, M; Wafford, KA; Whiting, PJ | 1 |
| Ballabeni, V; Barocelli, E; Calcina, F; Carelli, V; Di Stefano, A; Giorgioni, G; Impicciatore, M; Liberatore, F; Magnanini, F; Scipione, L | 1 |
| Mathers, DA; Puil, E; Wan, X | 2 |
| Birnir, B; Lim, MS; Lindquist, CE | 1 |
| Belknap, JK; Buck, KJ; Crabbe, JC; Fehr, C; Kosobud, AE; Metten, P; Shirley, RL | 1 |
| Martínez-Torres, A; Miledi, R | 1 |
| Chen, Z; Dillon, GH; Huang, RQ | 1 |
| Ellsworth, K; Ellsworth, M; Fisher, RS; Schroeder, KM; Smith, K; Wu, J | 1 |
| Yelmen, KN | 1 |
| Bianchi, MT; Feng, HJ; Macdonald, RL | 1 |
| Besheer, J; Hodge, CW | 1 |
| France, CP; McMahon, LR | 1 |
| Behar, KL; de Graaf, RA; Mason, GF; Patel, AB; Rothman, DL; Shulman, RG | 1 |
| Asproni, B; Biggio, G; Busonero, F; Cerri, R; Maciocco, E; Mascia, MP; Pau, A; Sanna, E; Talani, G | 1 |
| Ben-Ari, Y; Chiron, C; Gozlan, H; Quilichini, PP | 1 |
| Kulkarni, SK; Kumar, A | 1 |
| Drafts, BC; Fisher, JL | 1 |
| Avallone, R; Baraldi, M; Brusiani, F; Losi, G; Puia, G; Rivasi, M; Zanoli, P; Zavatti, M | 1 |
| Archer, DP; Nguyen, KQ; Roth, SH; Samanani, N | 1 |
| Chu, QP; Cui, XY; Fu, HZ; Lin, SQ; Lin, ZB; Wang, LE; Zhang, YH | 1 |
| Devor, M; Reiner, K; Sukhotinsky, I | 1 |
| Enrique Jiménez-Ferrer, J; Gutiérrez, C; Herrera-Ruiz, M; León, I; Mirón, G; Tortoriello, J | 1 |
| Cai, Y; Chen, C; Fei, J; Gong, N; Wang, Z; Wu, Y; Xu, T; Xu, Y; Zhang-Nunes, S | 1 |
| Eun, JS; Han, H; Hong, JT; Kim, HC; Ma, Y; Oh, KW | 1 |
| Gage, PW; Luu, T; Tierney, ML | 1 |
| Han, H; Hong, JT; Kim, YB; Ma, Y; Nam, SY; Oh, KW; Yun, YP | 1 |
| Czajkowski, C; Mercado, J | 1 |
| Prakash, T; Rao, NR; Swamy, AH | 1 |
| Alonso-Cortes, D; del Carmen Gutiérrez, M; Estrada-Soto, S; Herrera-Ruiz, M; León-Rivera, I; Mirón-López, G; Molina-Salinas, GM; Navarrete-Vázquez, G; Ríos, MY; Said-Fernández, S | 1 |
| Czajkowski, C; Jackson, MB; Muroi, Y; Theusch, CM | 1 |
| Burkat, PM; Gingrich, KJ; Roberts, WA | 1 |
| Akk, G; Bracamontes, J; Li, P; Steinbach, JH | 1 |
| Baptiste, SL; Devinsky, O; French, JA; Kuzniecky, RI; Ludvig, N; Tang, HM | 1 |
| Fisher, JL; Fisher, MT | 1 |
| Bäckström, T; Johansson, IM; Rahman, M; Wang, MD | 1 |
| Dougherty, DA; Hanek, AP; Lester, HA | 1 |
| Andrews-Zwilling, Y; Bernardo, A; Bien-Ly, N; Chen, L; Huang, Y; Li, G; Xu, Q; Yan, TX; Yoon, SY; Zwilling, D | 1 |
| Coyne, L; Halliwell, RF; Hirakawa, R; Przyborski, SA; Shan, M | 1 |
| Dong, J; Li, P; Liu, YF; Luo, J; Min, S; Wei, K | 1 |
| Czajkowski, C; Venkatachalan, SP | 1 |
| Dabole, B; Dawe, A; De Waard, M; Dimo, T; Djomeni Dzeufiet, PD; Ngo Bum, E; Okomolo Moto, FC; Sidiki, N; Sotoing Taïwe, G; Talla, E; Temkou Ngoupaye, G | 1 |
| Akaike, N; Iwata, S; Kotani, N; Nonaka, K; Shin, MC; Wakita, M | 1 |
| Akk, G; Eaton, MM; Li, P; Steinbach, JH | 1 |
| Barg, S; Birnir, B; Jin, Y; Jin, Z; Korol, SV | 1 |
| Han, JY; Hong, JT; Lee, CI; Oh, KW | 1 |
| Grauer, M; Jabs, R; Passlick, S; Schäfer, C; Seifert, G; Steinhäuser, C | 1 |
| Cho, S; Han, D; Jin, YH; Jin, Z; Kim, IH; Kim, S | 1 |
| Akk, G; Li, P | 1 |
| Augustine, GJ; Ganapathy, V; Goh, EL; Han, J; Hsu, KS; Leong, WY; Ma, D; Marcy, G; Ming, GL; Van Dongen, AM; Yang, CH; Yoon, SI; Zhao, N | 1 |
| He, J; Lei, JP; Liao, DG; Liu, F; Liu, H; Luo, K; Song, Z; Yang, L; Zhang, TY; Zhuang, K | 1 |
| Cheong, JH; Gao, Q; Hong, E; Jang, DS; Jeon, SJ; Lee, HE; Park, HJ; Park, SJ; Ryu, JH; Shin, CY | 1 |
| Ge, Y; Huang, Y; Li, Y; Ma, W; Zhao, W | 1 |
| Andrews-Zwilling, Y; Huang, Y; Lei, H; Lin, V; Tong, LM; Yang, A; Yoon, SY | 1 |
| Hong, KB; Park, Y; Suh, HJ | 1 |
| Pérez-Isidoro, R; Ruiz-Suárez, JC | 1 |
| Czajkowski, C; Ghosh, B; Tsao, TW | 1 |
| Akk, G; Germann, AL; Shin, DJ; Steinbach, JH | 1 |
| Du, J; Qiu, L; Qiu, M; Yu, Y; Zhu, Q | 1 |
| Huang, AX; Liu, WL; Shang, JH; Wu, BF; Zhao, YL | 1 |
| Chen, Q; Chen, X; Chen, Y; Du, J; Feng, H; Hao, J; Jia, X; Li, H; Ma, Y; Szeto, I; Zhang, Y; Zhao, Z; Zhou, W; Zhuang, W | 1 |
| Akk, G; Burbridge, AB; Germann, AL; Pierce, SR | 1 |
| Benz, A; Lambert, PM; Mennerick, S; Ni, R; Rensing, NR; Wong, M; Zorumski, CF | 1 |
| Chai, X; Chen, S; Gao, X; Huang, L; Jiao, S; Li, J; Ma, X; Tu, P; Wuken, S | 1 |
| Feng, X; Li, K; Li, R; Mao, S; Mu, K; Yang, P; Zhang, D; Zhang, J | 1 |
| Ago, Y; Doi, M; Irifune, M; Katayama, S; Kikuchi, Y; Morioka, N; Mukai, A; Nakata, Y; Okada, Y; Oue, K; Sakai, N; Shimizu, Y; Yoshida, M | 1 |
| Ahn, Y; Hong, KB; Park, CW; Suh, HJ | 1 |
5 review(s) available for pentobarbital and gamma-aminobutyric acid
| Article | Year |
|---|---|
Reinterpretation of the literature indicates differential sensitivities of long-sleep and short-sleep mice are not specific to alcohol.
Topics: Animals; Anti-Anxiety Agents; Barbital; Benzodiazepines; Central Nervous System Depressants; Circadian Rhythm; Convulsants; Dopamine; Electroencephalography; Ethanol; gamma-Aminobutyric Acid; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred Strains; Models, Genetic; Norepinephrine; Pentobarbital; Pharmacogenetics; Phenotype; Sex Factors; Sleep; Synaptic Transmission | 1985 |
[Pre-synaptic inhibition and pentobarbital].
Topics: Animals; Cell Membrane Permeability; Chlorine; Electric Conductivity; gamma-Aminobutyric Acid; In Vitro Techniques; Ions; Membrane Potentials; Neural Inhibition; Neurons, Afferent; Pentobarbital; Rana catesbeiana; Receptors, GABA-A | 1985 |
Chemically induced ion channels in nerve cell membranes.
Topics: Acetylcholine; Animals; Barbiturates; Benzodiazepines; Cell Membrane; Cells, Cultured; Central Nervous System; Convulsants; Culture Techniques; Decapodiformes; Electricity; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Autonomic; Ganglia, Sympathetic; Glutamates; Glutamic Acid; Glycine; Ion Channels; Mollusca; Muscarine; Neurons; Nicotine; Pentobarbital; Spinal Cord; Vertebrates | 1982 |
Benzodiazepine-GABA receptor-ionophore complex. Current concepts.
Topics: Animals; Benzodiazepines; Ethanol; gamma-Aminobutyric Acid; Humans; Hypertension; Ionophores; Ligands; Pentobarbital; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Anticonvulsant therapy in small animals.
Topics: Acetates; Amines; Animals; Anticonvulsants; Bromides; Clonazepam; Clorazepate Dipotassium; Cyclohexanecarboxylic Acids; Diazepam; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Mephenytoin; Pentobarbital; Phenobarbital; Phenylcarbamates; Phenytoin; Primidone; Propylene Glycols; Seizures; Valproic Acid | 1998 |
464 other study(ies) available for pentobarbital and gamma-aminobutyric acid
| Article | Year |
|---|---|
Mechanism of action of anticonvulsants. Role of the differential effects on the active uptake of putative neurotransmitters.
Topics: Animals; Anticonvulsants; Brain; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Hypnotics and Sedatives; In Vitro Techniques; Neurotransmitter Agents; Norepinephrine; Pentobarbital; Phenytoin; Rats | 1976 |
The action of pentobarbital on the amino acid induced depolarization of primary afferents in the frog.
Topics: Alanine; Amino Acids; Animals; gamma-Aminobutyric Acid; Glutamates; Hydrogen-Ion Concentration; In Vitro Techniques; Neuromuscular Depolarizing Agents; Neurons, Afferent; Pentobarbital; Taurine | 1976 |
[Modification of curarization after acute administration of 2 antiepileptic drugs].
Topics: Animals; Anticonvulsants; Carbamazepine; Cyclic AMP; Drug Synergism; gamma-Aminobutyric Acid; Male; Neuromuscular Nondepolarizing Agents; Pancuronium; Pentobarbital; Pyridinium Compounds; Rats; Valproic Acid | 1979 |
Drug-induced rhythmical activity in the inferior olivary complex of the rat.
Topics: Acetylcholine; Action Potentials; Animals; Atropine; Bicuculline; Dopamine; Fenclonine; Gallamine Triethiodide; gamma-Aminobutyric Acid; Glutamates; Glycine; Harmaline; Harmine; Male; Neurons; Norepinephrine; Olivary Nucleus; Pentobarbital; Rats; Serotonin; Strychnine; Tryptamines; Tubocurarine | 1976 |
Effects of stimulatory and depressant drugs on cyclic guanosine 3',5'-monophosphate and adenosine 3',5'-monophosphate levels in mouse brain.
Topics: Animals; Atropine; Brain; Brain Chemistry; Convulsants; Cyclic AMP; Cyclic GMP; Diazepam; Drug Interactions; gamma-Aminobutyric Acid; Harmaline; Male; Mice; Oxotremorine; Pentobarbital; Pentylenetetrazole; Picrotoxin; Tremor | 1976 |
Barbiturate reversal of amino acid antagonism produced by convulsant agents.
Topics: Aminobutyrates; Animals; Barbiturates; Bicuculline; Binding Sites; Brain Stem; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Autonomic; Glycine; Isoquinolines; Neurons; Pentobarbital; Rats; Receptors, Neurotransmitter; Strychnine | 1976 |
Pentobarbital: differential postsynaptic actions on sympathetic ganglion cells.
Topics: Animals; Anura; Carbachol; gamma-Aminobutyric Acid; Ganglia, Autonomic; In Vitro Techniques; Membrane Potentials; Neural Inhibition; Pentobarbital; Rana catesbeiana; Receptors, Nicotinic; Synaptic Membranes; Synaptic Transmission | 1978 |
Different actions of anticonvulsant and anesthetic barbiturates revealed by use of cultured mammalian neurons.
Topics: Action Potentials; Cells, Cultured; Electric Conductivity; gamma-Aminobutyric Acid; Glutamates; Membrane Potentials; Neurons; Pentobarbital; Phenobarbital; Picrotoxin; Receptors, Neurotransmitter | 1978 |
Anticonvulsant and anesthetic barbiturates: different postsynaptic actions in cultured mammalian neurons.
Topics: Animals; Barbiturates; Chlorides; Culture Techniques; gamma-Aminobutyric Acid; Glutamates; Ion Channels; Membrane Potentials; Mephobarbital; Mice; Neural Inhibition; Neurons; Pentobarbital; Phenobarbital; Secobarbital; Spinal Cord; Synapses; Synaptic Transmission | 1979 |
Potentiation of the effects of GABA by pentobarbitone.
Topics: Animals; Bicuculline; Dose-Response Relationship, Drug; Drug Synergism; Evoked Potentials; gamma-Aminobutyric Acid; Ganglia, Autonomic; Ganglia, Spinal; Nipecotic Acids; Pentobarbital; Rats; Receptors, Neurotransmitter; Spinal Cord | 1979 |
Cortical release of labeled compounds during arousal in the cat: correlations with carbon dioxide, brain temperature and EEG.
Topics: Aminobutyrates; Animals; Arousal; Body Temperature; Calcium; Calcium Chloride; Calcium Radioisotopes; Carbon Dioxide; Carbon Radioisotopes; Cats; Cerebral Cortex; Cyanides; Electroencephalography; Gallamine Triethiodide; gamma-Aminobutyric Acid; Lysine; Norepinephrine; Pentobarbital; Respiration; Serotonin; Taurine; Tritium; Water | 1975 |
Pentobarbital depression of stimulus-secretion coupling in brain--selective inhibition of depolarization-induced calcium-dependent release.
Topics: Animals; Brain; Calcimycin; Calcium; Depression, Chemical; gamma-Aminobutyric Acid; In Vitro Techniques; Mice; Norepinephrine; Pentobarbital; Potassium; Synaptosomes; Veratridine | 1977 |
Effect of barbiturates on release endogenous amino acids from rat cortex slices.
Topics: Amino Acids; Animals; Barbiturates; Calcimycin; Calcium; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamates; In Vitro Techniques; Ouabain; Pentobarbital; Potassium; Rats; Veratridine | 1979 |
Effect of pentobarbitone on the spontaneous efflux of gamma-amino acids from rabbit retina.
Topics: Alanine; Animals; Autoradiography; Butyrates; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Glycine; Male; Neuroglia; Neurons; Pentobarbital; Photic Stimulation; Rabbits; Retina | 1979 |
Pentobarbitone affects post-synaptic inhibition by presynaptic mechanisms [proceedings].
Topics: Animals; Astacoidea; Evoked Potentials; gamma-Aminobutyric Acid; Mechanoreceptors; Neural Inhibition; Pentobarbital; Synapses | 1979 |
Modification of GABA-mediated depolarization of the cat ganglion by pentobarbital and two benzodiazepines.
Topics: Animals; Benzodiazepines; Bicuculline; Cats; Flurazepam; gamma-Aminobutyric Acid; Ganglia, Spinal; Pentobarbital; Picrotoxin | 1979 |
Gamma-Aminobutyric acid and primary afferent depolarization in feline spinal cord.
Topics: Animals; Bicuculline; Cats; Female; gamma-Aminobutyric Acid; Male; Membrane Potentials; Neuromuscular Depolarizing Agents; Neurons, Afferent; Nipecotic Acids; Pentobarbital; Semicarbazides; Spinal Cord; Time Factors | 1979 |
GABA-mediated biphasic inhibitory responses in hippocampus.
Topics: Action Potentials; Animals; Chlorides; Electric Stimulation; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Mice; Neural Inhibition; Pentobarbital; Tetrodotoxin | 1979 |
Photic release of radioactivity from rabbit retina preloaded with [3H]GABA.
Topics: Aminobutyrates; Animals; Autoradiography; Female; gamma-Aminobutyric Acid; Light; Male; Pentobarbital; Photic Stimulation; Rabbits; Retina; Tritium | 1978 |
Effect of diazepam and pentobarbital on aminooxyacetic acid-induced accumulation on GABA.
Topics: Acetates; Aminobutyrates; Aminooxyacetic Acid; Animals; Brain; Diazepam; gamma-Aminobutyric Acid; Male; Pentobarbital; Rats; Tissue Distribution | 1977 |
Effect of pentobarbitone on the inhibition of spinal interneurones in the cat by glycine and GABA [proceedings].
Topics: Aminobutyrates; Animals; Cats; gamma-Aminobutyric Acid; Glycine; Interneurons; Pentobarbital; Spinal Cord | 1977 |
GABA-potentiating action of pentobarbitone on the isolated superior cervical ganglion of the rat [proceedings].
Topics: Aminobutyrates; Animals; gamma-Aminobutyric Acid; Ganglia, Autonomic; In Vitro Techniques; Pentobarbital; Rats | 1977 |
Pentobarbitone enhancement of the inhibitory action of GABA.
Topics: Aminobutyrates; Animals; Cats; Drug Synergism; gamma-Aminobutyric Acid; Interneurons; Neural Inhibition; Pentobarbital; Spinal Cord | 1977 |
Photic evoked response in the optic tectum of young chicks: effect of pentobarbitone and gamma aminobutyric acid (GABA) [proceedings].
Topics: Aminobutyrates; Animals; Chickens; Evoked Potentials; gamma-Aminobutyric Acid; Pentobarbital; Photic Stimulation; Superior Colliculi | 1977 |
Effects of benzodiazepines and pentobarbitone on the gaba-ergic recurrent inhibition of hippocampal neurons.
Topics: Action Potentials; Aminobutyrates; Animals; Benzodiazepines; Bicuculline; Cats; Diazepam; Drug Synergism; Female; gamma-Aminobutyric Acid; Hippocampus; Male; Neural Inhibition; Neurons; Pentobarbital | 1978 |
Effects of centrally affecting drugs on the diuretic and antidiuretic actions of intracerebroventricular prostaglandin E2.
Topics: Amitriptyline; Animals; Central Nervous System; Diazepam; Diuresis; Drug Interactions; gamma-Aminobutyric Acid; Injections, Intraventricular; Morphine; Norepinephrine; Pentobarbital; Prostaglandins E; Rats; Reserpine; Time Factors | 1978 |
Pentobarbitone pharmacology of mammalian central neurones grown in tissue culture.
Topics: Animals; Central Nervous System; Culture Techniques; gamma-Aminobutyric Acid; Glutamates; Kinetics; Membrane Potentials; Mice; Mice, Inbred C57BL; Neurons; Pentobarbital; Synapses | 1978 |
Potentiation of the effects of GABA by pentobarbitone in the rat [proceedings].
Topics: Animals; Drug Interactions; Evoked Potentials; gamma-Aminobutyric Acid; Neurons, Afferent; Pentobarbital; Rats; Spinal Nerve Roots | 1978 |
Inhibition of gamma-aminobutyric acid uptake into astrocytes by pentobarbital.
Topics: Astrocytes; Cells, Cultured; gamma-Aminobutyric Acid; Pentobarbital; Potassium; Time Factors | 1978 |
Inhibition of gamma-aminobutyric acid release from rat cerebral cortex slices by barbiturate anesthesia.
Topics: Amino Acids; Amobarbital; Anesthesia, General; Animals; Barbiturates; Cerebral Cortex; gamma-Aminobutyric Acid; Male; Pentobarbital; Potassium; Rats | 1978 |
Influence of pentobarbital on synaptic plasma membrane protein synthesis.
Topics: Animals; Brain; Drug Tolerance; gamma-Aminobutyric Acid; Male; Membrane Proteins; Nerve Endings; Nerve Tissue Proteins; Pentobarbital; Rats; Synaptic Membranes; Time Factors | 1977 |
The effects of gamma-aminobutyric acid on prolactin and gonadotropin secretion in the unanesthetized rat.
Topics: Aminobutyrates; Animals; Follicle Stimulating Hormone; gamma-Aminobutyric Acid; Luteinizing Hormone; Male; Pentobarbital; Prolactin; Rats | 1977 |
Effects of acute and continuous pentobarbital administration on the gamma-aminobutyric acid system.
Topics: Aminobutyrates; Aminooxyacetic Acid; Animals; Brain; Drug Tolerance; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamates; Male; Mice; Pentobarbital; Sleep | 1977 |
Barbiturate potentiation of hippocampal i.p.s.p.s is not mediated by blockade of GABA uptake [proceedings].
Topics: Aminobutyrates; Animals; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Pentobarbital; Synaptic Membranes | 1977 |
Pentobarbital selectively enhances GABA-mediated post-synaptic inhibition in tissue cultured mouse spinal neurons.
Topics: Aminobutyrates; Animals; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glycine; Kinetics; Membrane Potentials; Mice; Neural Inhibition; Neurons; Pentobarbital; Spinal Cord; Synaptic Membranes; Time Factors | 1976 |
[Chemical heterogenicity of the synaptic organization of different regions of the rabbit cerebral cortex].
Topics: Aminobutyrates; Animals; Cerebral Cortex; Evoked Potentials; gamma-Aminobutyric Acid; Glycine; Male; Pentobarbital; Rabbits; Somatosensory Cortex; Visual Cortex | 1976 |
Presynaptic action of barbiturates in the frog spinal cord.
Topics: Alanine; Animals; gamma-Aminobutyric Acid; Ganglia, Spinal; Glutamates; Membrane Potentials; Pentobarbital; Rana pipiens; Spinal Cord; Synapses; Time Factors | 1975 |
[A pharmacologic analysis of the slow potential arising in response to adequate stimulation of the frog olfactory bulb].
Topics: Animals; Anura; Chloralose; gamma-Aminobutyric Acid; Membrane Potentials; Morphine; Olfactory Bulb; Penicillins; Pentobarbital; Picrotoxin; Rana temporaria; Strychnine | 1975 |
Pentobarbital modulates transmitter effects on mouse spinal neurones grown in tissue culture.
Topics: Aminobutyrates; Anesthesia, General; Animals; Culture Techniques; Depression, Chemical; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Iontophoresis; Membrane Potentials; Mice; Neural Conduction; Neurons; Pentobarbital; Spinal Cord | 1975 |
Release of (3H)GABA and (14C)glutamic acid from rat cortex slices: the relationship between the tissue pool size and rates of spontaneous and electrically induced release.
Topics: Aminobutyrates; Animals; Cerebral Cortex; Electric Stimulation; Female; gamma-Aminobutyric Acid; Glutamates; In Vitro Techniques; Male; Ouabain; Pentobarbital; Potassium; Rats; Time Factors | 1975 |
The effects of some newer anaesthetics on the in vitro activity of glutamate decarboxylase and GABA transaminase in crude brain extracts and on the levels of amino acids in vivo.
Topics: 4-Aminobutyrate Transaminase; Alfaxalone Alfadolone Mixture; Amino Acids; Anesthetics; Animals; Brain; Carboxy-Lyases; Chromatography, Thin Layer; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamates; Hydroxybutyrates; Hydroxysteroids; Ketamine; Male; Methohexital; Mice; Pentobarbital; Pregnanediones; Succinates; Thiopental; Transaminases | 1975 |
CNS depressants: effects on post-synaptic pharmacology.
Topics: Acetylcholine; Animals; Astacoidea; Chloralose; Chlorides; Chloroform; Dopamine; Dose-Response Relationship, Drug; Ethanol; gamma-Aminobutyric Acid; Glutamates; Membrane Potentials; Nephropidae; Neuromuscular Junction; Pentobarbital; Phenytoin; Potassium; Serotonin; Snails; Sodium; Synapses; Urethane; Vasopressins | 1975 |
Divalent cations: effects on post-synaptic pharmacology of invertebrate synapses.
Topics: Acetylcholine; Action Potentials; Animals; Astacoidea; Calcium; Chlorides; Cobalt; Dopamine; gamma-Aminobutyric Acid; Glutamates; In Vitro Techniques; Iontophoresis; Magnesium; Membrane Potentials; Nephropidae; Neuromuscular Junction; Pentobarbital; Potassium; Snails; Sodium; Strontium; Synapses | 1975 |
Pentobarbital: action on frog motoneurons.
Topics: Animals; Anura; Aspartic Acid; Bicuculline; Cell Membrane Permeability; Depression, Chemical; Drug Interactions; gamma-Aminobutyric Acid; Glutamates; Membrane Potentials; Motor Neurons; Pentobarbital; Picrotoxin | 1975 |
Studies on field potentials and on single cells in the inferior olivary complex of the rat.
Topics: Action Potentials; Animals; Dopamine; Evoked Potentials; Femoral Nerve; gamma-Aminobutyric Acid; Glycine; Homocysteine; Male; Neurons; Norepinephrine; Olivary Nucleus; Pentobarbital; Rats; Receptors, Drug; Serotonin | 1976 |
gamma-Hydroxybutyric acid binding sites: interaction with the GABA-benzodiazepine-picrotoxin receptor complex.
Topics: Animals; Brain; gamma-Aminobutyric Acid; Male; Pentobarbital; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sodium Oxybate; Synaptic Membranes | 1992 |
Perinatal protein deprivation enhances the anticonflict effect measured after chronic ethanol administration in adult rats.
Topics: Animals; Behavior, Animal; Diazepam; Drug Tolerance; Ethanol; Female; gamma-Aminobutyric Acid; Maternal-Fetal Exchange; Motor Activity; Pentobarbital; Pregnancy; Protein Deficiency; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1992 |
5 beta-pregnan-3 beta-ol-20-one, a specific antagonist at the neurosteroid site of the GABAA receptor-complex.
Topics: Animals; Benzodiazepines; Binding, Competitive; Flunitrazepam; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Pentobarbital; Pregnanolone; Rats; Rats, Inbred Strains | 1992 |
Alfaxalone, pentobarbital and diazepam potentiate gamma-aminobutyric acid-induced depolarizations in single myenteric neurons of guinea pig intestine.
Topics: Anesthetics; Animals; Diazepam; Drug Synergism; gamma-Aminobutyric Acid; Guinea Pigs; Hydrocortisone; Intestines; Male; Membrane Potentials; Muscimol; Pentobarbital; Pregnanediones; Receptors, GABA-A | 1992 |
Post-inhibitory excitation of adenosine on neurotransmission in guinea pig hippocampal slices.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenine Nucleotides; Adenosine; Animals; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Isoquinolines; Pentobarbital; Piperazines; Protein Kinase C; Synaptic Transmission | 1992 |
Assembly of functional GABAA receptors in insect cells using baculovirus expression vectors.
Topics: Animals; Baculoviridae; Bicuculline; Cattle; Cell Line; Cloning, Molecular; Evoked Potentials; gamma-Aminobutyric Acid; Genetic Vectors; Macromolecular Substances; Moths; Pentobarbital; Receptors, GABA-A; Recombinant Proteins; Transfection; Virulence Factors, Bordetella | 1992 |
Effects of sedatives on GABA-mediated chloride flux into cerebral cortical microsacs prepared from emotional and non-emotional mice.
Topics: Analysis of Variance; Animals; Blotting, Northern; Cerebral Cortex; Chlorides; Diazepam; Drug Synergism; Emotions; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Pentobarbital; Receptors, GABA-A; RNA, Messenger | 1992 |
The pharmacology of recombinant GABAA receptors containing bovine alpha 1, beta 1, gamma 2L sub-units stably transfected into mouse fibroblast L-cells.
Topics: Animals; Chlorides; GABA Antagonists; gamma-Aminobutyric Acid; L Cells; Ligands; Mice; Pentobarbital; Pregnanediones; Receptors, GABA-A; Recombinant Proteins; Transfection | 1992 |
GABA- and glutamate-activated currents in glial cells of the mouse corpus callosum slice.
Topics: Action Potentials; Animals; Bicuculline; Chloride Channels; Corpus Callosum; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Ion Channel Gating; Kainic Acid; Membrane Proteins; Mice; Muscimol; Oligodendroglia; Pentobarbital; Potassium Channels; Receptors, GABA-A; Receptors, Glutamate; Receptors, Neurotransmitter; Stem Cells | 1992 |
The general anesthetic propofol: a biochemical tool to study the function of the GABA-coupled chloride channel.
Topics: Anesthetics; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; gamma-Aminobutyric Acid; Ion Channels; Male; Pentobarbital; Pregnanediones; Propofol; Rats; Rats, Inbred Strains | 1992 |
Chloride current induced by alcohols in rat dorsal root ganglion neurons.
Topics: Alcohols; Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Chlordiazepoxide; Chloride Channels; Dose-Response Relationship, Drug; Drug Synergism; gamma-Aminobutyric Acid; Ganglia, Spinal; Ion Channels; Membrane Potentials; Membrane Proteins; Neurons; Pentobarbital; Picrotoxin; Rats; Structure-Activity Relationship | 1992 |
Dehydroepiandrosterone enhances the hypnotic and hypothermic effects of ethanol and pentobarbital.
Topics: Animals; Body Temperature; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Mice; Mice, Inbred C57BL; Pentobarbital; Sleep | 1992 |
Barbiturates suppress glucose utilization by inhibition of hexokinase in neuroblastoma cells.
Topics: 3-O-Methylglucose; Barbiturates; Biological Transport; Cell Line; Deoxyglucose; gamma-Aminobutyric Acid; Hexokinase; Humans; Kinetics; Methylglucosides; Neuroblastoma; Pentobarbital; Picrotoxin; Tumor Cells, Cultured | 1992 |
gamma-Aminobutyric acid-induced response in rat dissociated paratracheal ganglion cells.
Topics: Animals; Chlorides; Diazepam; Drug Synergism; Electric Conductivity; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia; Muscimol; Pentobarbital; Rats; Rats, Inbred Strains; Trachea | 1992 |
In vitro studies on the broad spectrum anticonvulsant loreclezole in the hippocampus.
Topics: Animals; Anticonvulsants; Calcium; Electric Stimulation; Epilepsy; Etomidate; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Magnesium Deficiency; Pentobarbital; Phenobarbital; Triazoles | 1992 |
gamma-Aminobutyric acid-activated chloride channels in rats selectively bred for differential acute sensitivity to alcohol.
Topics: Alcohol Drinking; Animals; Chloride Channels; Diazepam; Female; Flunitrazepam; gamma-Aminobutyric Acid; Membrane Proteins; Muscimol; Pentobarbital; Phenobarbital; Phenotype; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Selection, Genetic | 1991 |
The effects of pentobarbital and benzodiazepines on GABA-responses in the periphery and spinal cord in vitro.
Topics: Animals; Animals, Newborn; Benzodiazepines; Bicuculline; Evoked Potentials; gamma-Aminobutyric Acid; Male; Pentobarbital; Peripheral Nerves; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Spinal Cord; Synapses; Vagus Nerve | 1991 |
Gamma-aminobutyric acidA receptor complexes in rat frontal cortex and spinal cord show differential responses to steroid modulation.
Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chlorides; Desoxycorticosterone; Diazepam; gamma-Aminobutyric Acid; Ionophores; Male; Pentobarbital; Pregnanediol; Pregnanolone; Rats; Rats, Inbred Strains; Receptors, GABA-A; Spinal Cord; Steroids; Sulfur Radioisotopes | 1991 |
GABA/BZ-and NMDA-receptor interaction in digoxin-induced convulsions in rats.
Topics: Animals; Baclofen; Diazepam; Digoxin; Dizocilpine Maleate; Female; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Muscimol; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Salts; Seizures | 1991 |
Inhibitory transmission in the basolateral amygdala.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amygdala; Animals; Baclofen; Bicuculline; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Neural Inhibition; Pentobarbital; Potassium; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 1991 |
Factors affecting actions of ethanol on GABA-activated chloride channels.
Topics: Animals; Chlorides; Cold Temperature; Ethanol; Female; Flunitrazepam; gamma-Aminobutyric Acid; Ion Channels; Mice; Pentobarbital; Time Factors | 1990 |
[Pentobarbital interaction with the GABA-activated ion channels of the neurons in the rat cerebellum].
Topics: Animals; Cerebellum; Chlorides; Dose-Response Relationship, Drug; Drug Interactions; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Membrane Potentials; Neurons; Pentobarbital; Rats; Stimulation, Chemical | 1990 |
gamma-Aminobutyric acidA receptor regulation in culture: altered allosteric interactions following prolonged exposure to benzodiazepines, barbiturates, and methylxanthines.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Allosteric Regulation; Animals; Barbital; Barbiturates; Brain; Caffeine; Cells, Cultured; Chick Embryo; Flumazenil; Flunitrazepam; Flurazepam; gamma-Aminobutyric Acid; Kinetics; Neurons; Pentobarbital; Receptors, GABA-A; Tetrodotoxin; Theophylline; Veratridine | 1990 |
Effects of glycine and GABA on isolated bipolar cells of the mouse retina.
Topics: Action Potentials; Animals; Bicuculline; Chlorides; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Ion Channels; Mice; Neurons; Pentobarbital; Picrotoxin; Potassium; Retina; Sodium; Strychnine | 1990 |
GABAergic modulation of catecholamine release from cultured bovine adrenal chromaffin cells. Evidence for the involvement of Cl(-)-dependent Ca2+ entry.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Adrenal Glands; Animals; Calcium; Calcium Radioisotopes; Catecholamines; Cattle; Cells, Cultured; Chlorides; Chromaffin System; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Ion Channels; Muscimol; Pentobarbital; Time Factors; Veratridine | 1990 |
The effect of subunit composition of rat brain GABAA receptors on channel function.
Topics: Animals; Benzodiazepines; Binding Sites; Brain; Carbolines; Dactinomycin; Diazepam; gamma-Aminobutyric Acid; Ion Channel Gating; Ion Channels; Pentobarbital; Picrotoxin; Rats; Receptors, GABA-A; Xenopus | 1990 |
Expression of mammalian gamma-aminobutyric acid receptors with distinct pharmacology in Xenopus oocytes.
Topics: Animals; Baclofen; Bicuculline; Cattle; Cerebral Cortex; Electric Conductivity; gamma-Aminobutyric Acid; Gene Expression; Membrane Potentials; Oocytes; Pentobarbital; Picrotoxin; Poly A; Rats; Receptors, GABA-A; Retina; RNA; RNA, Messenger; Transfection; Xenopus | 1991 |
Quinolones and fenbufen interact with GABAA receptor in dissociated hippocampal cells of rat.
Topics: 4-Quinolones; Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Chloride Channels; Drug Interactions; Electrophysiology; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Ion Channels; Membrane Proteins; Muscimol; Neurons; Pentobarbital; Phenylbutyrates; Pyramidal Tracts; Rats; Rats, Inbred Strains; Receptors, GABA-A; Structure-Activity Relationship | 1991 |
Potentiation of gamma-aminobutyric acid-mediated chloride flux by pentobarbital and diazepam but not ethanol.
Topics: Animals; Brain; Chlorides; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred ICR; Osmolar Concentration; Pentobarbital; Rats; Rats, Inbred Strains | 1992 |
Arginine8-vasopressin potentiates the motor incoordinating effects of pentobarbital.
Topics: Animals; Arginine Vasopressin; Cerebellum; Cerebral Cortex; Chlorides; Drug Synergism; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Motor Activity; Pentobarbital; Rats; Rats, Inbred Strains | 1991 |
Benzodiazepines do not potentiate GABA responses in neonatal hippocampal neurons.
Topics: Animals; Animals, Newborn; Drug Interactions; Flunitrazepam; gamma-Aminobutyric Acid; Hippocampus; Iontophoresis; Male; Midazolam; Neurons; Pentobarbital; Rats; Rats, Inbred Strains | 1991 |
t-[35S]butylbicyclophosphorothionate binding under equilibrium and nonequilibrium conditions: differential effects of barbiturates and gamma-aminobutyric acid in the long-sleep and short-sleep selected mouse lines.
Topics: Animals; Barbiturates; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cerebellum; Cerebral Cortex; Chloride Channels; Ethanol; gamma-Aminobutyric Acid; Kinetics; Male; Membrane Proteins; Mice; Pentobarbital; Phenobarbital; Picrotoxin; Receptors, GABA-A; Sesterterpenes; Sleep | 1991 |
Pharmacologic characterization of GABAA/benzodiazepine receptor in rat hippocampus during aging.
Topics: Aging; Animals; Binding Sites; Cerebellum; Cerebral Cortex; Culture Techniques; Drug Interactions; Flunitrazepam; gamma-Aminobutyric Acid; Hippocampus; Male; Muscimol; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1991 |
Correlation between gamma-aminobutyric acidA receptor ligand-induced changes in t-butylbicyclophosphoro[35S]thionate binding and 36Cl- uptake in rat cerebrocortical membranes.
Topics: Animals; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carbolines; Cerebral Cortex; Chloride Channels; Chlorides; Desoxycorticosterone; Diazepam; Ethanol; Flumazenil; gamma-Aminobutyric Acid; In Vitro Techniques; Ligands; Membrane Proteins; Pentobarbital; Pregnanolone; Rats; Receptors, GABA-A; Synaptosomes | 1991 |
Reticulospinal vasomotor neurones in decerebrate rats: effect of pentobarbitone.
Topics: Animals; Decerebrate State; gamma-Aminobutyric Acid; Heart Rate; Male; Muscle, Smooth, Vascular; Neurons; Pentobarbital; Rats; Rats, Inbred Strains; Reticular Formation; Spinal Cord; Vasomotor System | 1991 |
Halothane enhances tonic neuronal inhibition by elevating intracellular calcium.
Topics: Animals; Bicuculline; Calcium; Dantrolene; Egtazic Acid; Evoked Potentials; gamma-Aminobutyric Acid; Halothane; Hippocampus; In Vitro Techniques; Male; Neurons; Pentobarbital; Pyramidal Tracts; Rats; Rats, Inbred Strains; Synapses | 1991 |
Differences among effects of sedative-hypnotic drugs on GABA-mediated chloride flux: quench flow studies.
Topics: Animals; Cerebral Cortex; Chlorides; Diazepam; Ethanol; gamma-Aminobutyric Acid; Hypnotics and Sedatives; In Vitro Techniques; Male; Pentobarbital; Rats; Rats, Inbred Strains | 1991 |
Locally evoked potentials in slices of the rat nucleus accumbens: NMDA and non-NMDA receptor mediated components and modulation by GABA.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Atropine; Axons; Dipeptides; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Kynurenic Acid; Male; Neurons; Neurotoxins; Nucleus Accumbens; Pentobarbital; Picrotoxin; Pyridostigmine Bromide; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tetrodotoxin; Time Factors; Tubocurarine | 1990 |
gamma-Aminobutyric acid-induced response in acutely isolated nucleus solitarii neurons of the rat.
Topics: Animals; Bicuculline; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Medulla Oblongata; Membrane Potentials; Muscimol; Neurons; Penicillin G; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Strychnine | 1991 |
Electrophysiology of ethanol, nitrous oxide, and barbiturate on presumed subtypes of cerebellar granule cells.
Topics: Acoustic Stimulation; Animals; Cats; Cerebellum; Ethanol; gamma-Aminobutyric Acid; Nitrous Oxide; Pentobarbital | 1991 |
Two mechanisms for anesthetic-induced enhancement of GABAA-mediated neuronal inhibition.
Topics: Anesthetics; Animals; Brain; Drug Synergism; Evoked Potentials; gamma-Aminobutyric Acid; Halothane; In Vitro Techniques; Models, Neurological; Neurons; Pentobarbital | 1991 |
[The effect of the newly synthesized barbiturate HB-7, phenobarbital and pentobarbital on the GABA content of the brain in rats].
Topics: Animals; Anticonvulsants; Brain Chemistry; Dominance, Cerebral; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Pentobarbital; Phenobarbital; Rats | 1990 |
Studies on the mechanism of interactions between anesthetic steroids and gamma-aminobutyric acidA receptors.
Topics: Anesthetics; Animals; Chlorides; Desoxycorticosterone; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Nipecotic Acids; Pentobarbital; Pregnanolone; Progesterone; Proline; Rats; Receptors, GABA-A; Synaptic Membranes | 1990 |
Cerebral radioprotection by pentobarbital: dose-response characteristics and association with GABA agonist activity.
Topics: Anesthesia, General; Animals; Brain; Diazepam; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; gamma-Aminobutyric Acid; Hypothermia; Male; Pentobarbital; Radiation Tolerance; Radiation-Protective Agents; Rats; Rats, Inbred F344; Receptors, GABA-A; Survival Rate | 1990 |
Neurosteroids act on recombinant human GABAA receptors.
Topics: Benzodiazepines; Cell Line, Transformed; Cell Membrane Permeability; Chlorides; Desoxycorticosterone; Electric Conductivity; Flunitrazepam; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Kidney; Membrane Potentials; Pentobarbital; Pregnanolone; Receptors, GABA-A; Recombinant Proteins; Transfection | 1990 |
Functional characteristics and sites of gene expression of the alpha 1, beta 1, gamma 2-isoform of the rat GABAA receptor.
Topics: Amino Acid Sequence; Animals; Animals, Newborn; Base Sequence; Brain; Cloning, Molecular; gamma-Aminobutyric Acid; Gene Expression; Macromolecular Substances; Membrane Potentials; Molecular Sequence Data; Oocytes; Organ Specificity; Pentobarbital; Picrotoxin; Rats; Receptors, GABA-A; RNA, Messenger; Xenopus laevis | 1990 |
Characterization of GABAergic seizure regulation in the midline thalamus.
Topics: Animals; Baclofen; Bicuculline; Electroencephalography; Epilepsy; Female; Flurazepam; gamma-Aminobutyric Acid; Pentobarbital; Pentylenetetrazole; Piperidines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Thalamic Nuclei | 1990 |
GABAA-receptor-activated current in dorsal root ganglion neurons freshly isolated from adult rats.
Topics: Animals; Flurazepam; gamma-Aminobutyric Acid; Ganglia, Spinal; In Vitro Techniques; Male; Membrane Potentials; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1990 |
Evidence for functionally distinct subclasses of gamma-aminobutyric acid receptors in rabbit retina.
Topics: Acetylcholine; Amino Acids; Amino Acids, Neutral; Animals; Baclofen; Binding, Competitive; Cell Fractionation; Flurazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Light; Models, Theoretical; Pentobarbital; Picrotoxin; Rabbits; Receptors, GABA-A; Retina | 1990 |
Pharmacological characteristics of two different types of inhibitory GABA receptors on Achatina fulica neurones.
Topics: Animals; Baclofen; Bicuculline; Crotonates; Diazepam; Dibenzazepines; Electrophysiology; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Muscimol; Neurons; Pentobarbital; Picrotoxin; Receptors, GABA-A; Snails | 1990 |
The general anesthetic propofol enhances the function of gamma-aminobutyric acid-coupled chloride channel in the rat cerebral cortex.
Topics: Anesthetics; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chloride Channels; gamma-Aminobutyric Acid; Male; Membrane Proteins; Pentobarbital; Picrotoxin; Pregnanediones; Propofol; Rats; Rats, Inbred Strains | 1990 |
Augmentation of GABA-induced current in frog sensory neurons by pentobarbital.
Topics: Animals; Dose-Response Relationship, Drug; Drug Synergism; Electric Conductivity; gamma-Aminobutyric Acid; Ganglia, Spinal; In Vitro Techniques; Membrane Potentials; Neurons, Afferent; Pentobarbital; Rana catesbeiana | 1990 |
Enhancement of current induced by superfusion of GABA in locus coeruleus neurons by pentobarbital, but not ethanol.
Topics: Animals; Ethanol; gamma-Aminobutyric Acid; In Vitro Techniques; Locus Coeruleus; Male; Membrane Potentials; Pentobarbital; Rats; Rats, Inbred F344 | 1990 |
[Acetylcholinesterase activity in blood plasma and various regions of the central nervous system of rats poisoned with lindane. Effect of sodium pentobarbital].
Topics: Acetylcholinesterase; Animals; Anticonvulsants; Brain; gamma-Aminobutyric Acid; Hexachlorocyclohexane; Male; Pentobarbital; Rats; Rats, Inbred Strains; Seizures; Spinal Cord; Synaptosomes | 1985 |
Gamma-aminobutyric acid uptake and the termination of inhibitory synaptic potentials in the rat hippocampal slice.
Topics: Action Potentials; Animals; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Ion Channels; Kinetics; Male; Models, Biological; Neurons; Nipecotic Acids; Pentobarbital; Proline; Rats; Rats, Inbred Strains; Synapses | 1985 |
Pentobarbital promotes bursts of gamma-aminobutyric acid-activated single channel currents in cultured mouse central neurons.
Topics: Animals; Cells, Cultured; Drug Synergism; gamma-Aminobutyric Acid; Ion Channels; Membrane Potentials; Mice; Pentobarbital; Spinal Cord | 1985 |
Interactions of gamma-aminobutyric acid (GABA), pentobarbital, and homopantothenic acid (HOPA) on internally perfused frog sensory neurons.
Topics: Animals; Cell Separation; Chlorides; Dose-Response Relationship, Drug; Drug Interactions; gamma-Aminobutyric Acid; Ganglia, Spinal; Ion Channels; Membrane Potentials; Neurons, Afferent; Pantothenic Acid; Pentobarbital; Perfusion; Ranidae | 1985 |
Local stimulation induced GABAergic response in rat striatal slice preparations: intracellular recordings on QX-314 injected neurons.
Topics: Animals; Chlorides; Corpus Striatum; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Lidocaine; Pentobarbital; Rats; Sodium; Synaptic Transmission | 1985 |
[Gamma-aminobutyric acid (GABA) activates three types of receptor-ionophore complex].
Topics: Animals; Chlorine; Diazepam; Drug Synergism; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Kinetics; Neurons, Afferent; Pentobarbital; Perfusion; Rana catesbeiana; Receptors, GABA-A | 1985 |
Anesthetic and convulsant barbiturates alter gamma-aminobutyric acid-stimulated chloride flux across brain membranes.
Topics: Animals; Barbiturates; Brain; Chlorides; Convulsants; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Male; Mice; Mice, Inbred DBA; Pentobarbital; Picrotoxin; Receptors, GABA-A; Stereoisomerism | 1986 |
gamma-Aminobutyric acid (GABA)- and barbiturate-mediated 36Cl- uptake in rat brain synaptoneurosomes: evidence for rapid desensitization of the GABA receptor-coupled chloride ion channel.
Topics: Animals; Cerebral Cortex; Chlorides; Dose-Response Relationship, Drug; Ethanol; gamma-Aminobutyric Acid; Ion Channels; Male; Muscimol; Pentobarbital; Ranidae; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes | 1986 |
Diazepam action on gamma-aminobutyric acid-activated chloride currents in internally perfused frog sensory neurons.
Topics: Animals; Benzodiazepinones; Chlorides; Diazepam; Drug Interactions; gamma-Aminobutyric Acid; Ganglia, Spinal; In Vitro Techniques; Ion Channels; Membrane Potentials; Neurons, Afferent; Pentobarbital; Rana catesbeiana | 1986 |
Characterization of spontaneous and evoked inhibitory postsynaptic potentials in rat supraoptic neurosecretory neurons in vitro.
Topics: Animals; Bicuculline; Chlorides; gamma-Aminobutyric Acid; Ion Channels; Male; Membrane Potentials; Neural Inhibition; Neurons; Neurosecretory Systems; Pentobarbital; Rats; Rats, Inbred Strains; Strychnine; Supraoptic Nucleus; Synapses | 1986 |
[GABA-activated conductance of mammalian cerebellar neurons].
Topics: Animals; Bicuculline; Chlorides; Diazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Membrane Potentials; Pentobarbital; Potassium; Purkinje Cells; Rats; Receptors, GABA-A | 1986 |
Spontaneous EEG spikes in the normal hippocampus. V. Effects of ether, urethane, pentobarbital, atropine, diazepam and bicuculline.
Topics: Anesthetics; Animals; Atropine; Behavior, Animal; Bicuculline; Diazepam; Electroencephalography; Ether; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Pentobarbital; Rats; Reference Values; Seizures; Urethane | 1988 |
Pentobarbital regulation of the kinetic properties of GABA receptor chloride channels.
Topics: Animals; Cells, Cultured; Chlorides; gamma-Aminobutyric Acid; Ion Channels; Kinetics; Mice; Neurons; Pentobarbital; Receptors, GABA-A | 1988 |
Aging reduces the GABA-dependent 36Cl- flux in rat brain membrane vesicles.
Topics: Aging; Animals; Bicuculline; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cerebellum; Cerebral Cortex; Chlorides; gamma-Aminobutyric Acid; Hippocampus; Ion Channels; Male; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1988 |
Kinetic and pharmacological properties of the GABA-induced chloride current in Aplysia neurones: a 'concentration clamp' study.
Topics: Animals; Aplysia; beta-Alanine; Chlorides; Diazepam; gamma-Aminobutyric Acid; Ion Channels; Kinetics; Muscimol; Neurons; Pentobarbital | 1988 |
Actions of anaesthetics and avermectin on GABAA chloride channels in mammalian dorsal root ganglion neurones.
Topics: Anesthetics; Animals; Cats; Cell Membrane; Chlorides; gamma-Aminobutyric Acid; Ganglia, Spinal; Hydrogen-Ion Concentration; In Vitro Techniques; Ion Channels; Ivermectin; Kinetics; Muscle Relaxation; Neurons; Pentobarbital; Rats | 1989 |
[The effect of pentobarbital on GABA-activated ionic currents of rat cerebellum neurons].
Topics: Animals; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Membrane Potentials; Pentobarbital; Purkinje Cells; Rats | 1989 |
Genotype-dependent effects of GABAergic agents on sedative properties of ethanol.
Topics: Animals; Bicuculline; Ethanol; gamma-Aminobutyric Acid; Genetics, Behavioral; Genotype; Hypnotics and Sedatives; Male; Mice; Mice, Inbred A; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Muscimol; Pentobarbital; Picrotoxin; Species Specificity | 1989 |
The tremorigen aflatrem is a positive allosteric modulator of the gamma-aminobutyric acidA receptor channel expressed in Xenopus oocytes.
Topics: Allosteric Regulation; Animals; Chloride Channels; Chlorides; Dose-Response Relationship, Drug; Flumazenil; gamma-Aminobutyric Acid; Indoles; Membrane Proteins; Mycotoxins; Oocytes; Pentobarbital; Picrotoxin; Receptors, GABA-A; Xenopus | 1989 |
Differential effects of iodide and chloride on allosteric interactions of the GABAA receptor.
Topics: Allosteric Regulation; Animals; Anions; Bicuculline; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Carbolines; Chlorides; Diazepam; gamma-Aminobutyric Acid; Iodides; Male; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1989 |
Effects of pentobarbitone, ketamine and lignocaine on synaptic transmission in the rat olfactory cortex in vitro.
Topics: Action Potentials; Animals; Aspartic Acid; Cerebral Cortex; Depression, Chemical; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; In Vitro Techniques; Ketamine; Lidocaine; Male; N-Methylaspartate; Olfactory Pathways; Oxadiazoles; Pentobarbital; Quisqualic Acid; Rats; Rats, Inbred Strains; Synapses; Synaptic Transmission | 1989 |
GABA receptors on the somatic muscle cells of the parasitic nematode, Ascaris suum: stereoselectivity indicates similarity to a GABAA-type agonist recognition site.
Topics: Animals; Ascaris; Baclofen; Binding, Competitive; Dieldrin; Electric Stimulation; Flurazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Muscles; Pentobarbital; Receptors, GABA-A; Stereoisomerism | 1989 |
Effects of intrahypothalamic injections of GABA, muscimol, pentobarbital, and L-glutamic acid on feed intake of satiated sheep.
Topics: Animals; Feeding Behavior; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hypothalamus; Male; Muscimol; Pentobarbital; Satiation; Sheep; Time Factors | 1989 |
Further characterisation of the [35S]-TBPS binding site of the GABA receptor complex in locust (Schistocerca gregaria) ganglia membranes.
Topics: Animals; Benzodiazepines; gamma-Aminobutyric Acid; Ganglia; Grasshoppers; Ligands; Membranes; Pentobarbital; Receptors, GABA-A | 1989 |
Circling evoked by intranigral SKF 38393: a GABA-mediated D-1 response?
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Colforsin; Dopamine Agents; Dose-Response Relationship, Drug; Drug Synergism; gamma-Aminobutyric Acid; Male; Motor Activity; Nipecotic Acids; Pentobarbital; Rats; Rats, Inbred Strains; Substantia Nigra | 1989 |
gamma-Aminobutyric-acid- and pentobarbitone-gated chloride currents in internally perfused frog sensory neurones.
Topics: Action Potentials; Amino Acids; Animals; Chlorides; Dose-Response Relationship, Drug; Drug Interactions; gamma-Aminobutyric Acid; Ganglia, Spinal; In Vitro Techniques; Ion Channels; Muscimol; Neurons, Afferent; Pentobarbital | 1985 |
The effect of ethanol on 35S-TBPS binding to mouse brain membranes in the presence of chloride.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Benzodiazepinones; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Chlorides; Diazepam; Drug Tolerance; Ethanol; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred C57BL; Pentobarbital; Substance-Related Disorders; Sulfur Radioisotopes | 1989 |
Comparative study on barbiturates using isolated single neurons: GABA-mimetic action and augmentatory action on GABA response.
Topics: Animals; Barbiturates; Chlorides; gamma-Aminobutyric Acid; Ganglia, Spinal; Hexobarbital; In Vitro Techniques; Membrane Potentials; Pentobarbital; Ranidae; Secobarbital | 1989 |
Pharmacology of a novel effect of gamma-aminobutyric acid on the frog optic tectum in vitro.
Topics: Animals; Bicuculline; Chlorides; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Midazolam; Muscimol; Pentobarbital; Rana temporaria; Superior Colliculi | 1989 |
Sodium pentobarbitone enhances responses of thalamic relay neurones to GABA in rat brain slices.
Topics: Animals; Brain; Drug Synergism; Electric Stimulation; Electrophysiology; Evoked Potentials; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Neurons; Pentobarbital; Rats; Synapses; Thalamus | 1989 |
Solubilisation of the gamma-aminobutyric acid/benzodiazepine receptor from rat cerebellum: optimal preservation of the modulatory responses by natural brain lipids.
Topics: Animals; Cerebellum; Cholesterol Esters; Cholic Acids; Flunitrazepam; gamma-Aminobutyric Acid; Glycine max; Lipids; Male; Pentobarbital; Phospholipids; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A; Solubility; Solutions; Synaptic Membranes | 1987 |
Characteristics of flunitrazepam binding to intact primary cultured spinal cord neurons and its modulation by GABAergic drugs.
Topics: Animals; Benzodiazepines; Binding, Competitive; Carbolines; Cells, Cultured; Embryo, Mammalian; Etazolate; Etomidate; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Mice; Mice, Inbred C57BL; Muscimol; Neurons; Pentobarbital; Receptors, GABA-A; Spinal Cord | 1987 |
gamma-Aminobutyric acid and pentobarbital enhance 2-[3H]oxoquazepam binding to type I benzodiazepine recognition sites in rat and human brain.
Topics: Adult; Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Brain; Chlorides; Drug Synergism; Female; Flunitrazepam; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A; Tritium | 1988 |
Chronic ethanol administration alters gamma-aminobutyric acid, pentobarbital and ethanol-mediated 36Cl- uptake in cerebral cortical synaptoneurosomes.
Topics: Administration, Inhalation; Animals; Cerebral Cortex; Chlorides; Dose-Response Relationship, Drug; Ethanol; gamma-Aminobutyric Acid; Male; Muscimol; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synapses | 1988 |
Changes in benzodiazepine/GABA receptor complex function in benzodiazepine-tolerant mice.
Topics: Animals; Anticonvulsants; Bicuculline; Body Temperature; Drug Tolerance; Flurazepam; gamma-Aminobutyric Acid; Infusions, Intravenous; Male; Mice; Motor Activity; Pentobarbital; Picrotoxin; Receptors, GABA-A; Seizures; Time Factors | 1988 |
Exacerbation of indomethacin-induced gastric ulceration by systemically administered GABA in rats: possible involvement of peripheral GABA receptors.
Topics: Animals; Anticonvulsants; Atropine; beta-Alanine; Bicuculline; Drug Synergism; gamma-Aminobutyric Acid; Glycine; Indomethacin; Male; Muscimol; Pentobarbital; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stomach Ulcer; Taurine | 1988 |
GABA-ergic mechanisms in the anticonvulsive activity of newly synthesized barbiturates. II. Correlation of HB-7 with GABA-ergic agents.
Topics: Animals; Anticonvulsants; Baclofen; Barbiturates; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Mice; Muscimol; Pentobarbital; Receptors, GABA-A | 1988 |
Effect of benzodiazepines and pentobarbital on the GABA-induced depolarization in cultured astrocytes.
Topics: Animals; Astrocytes; Benzodiazepines; Benzodiazepinones; Brain; Cells, Cultured; Flunitrazepam; gamma-Aminobutyric Acid; Membrane Potentials; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1988 |
Discriminative stimulus properties of CGS 9896: interactions within the GABA/benzodiazepine receptor complex.
Topics: Animals; Carbolines; Chlordiazepoxide; Discrimination, Psychological; Dose-Response Relationship, Drug; Flumazenil; gamma-Aminobutyric Acid; Male; Pentobarbital; Pentylenetetrazole; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1988 |
Interoceptive stimuli produced by an anxiogenic drug are mimicked by benzodiazepine antagonists in rats pretreated with isoniazid.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Benzodiazepinones; Brain Chemistry; Convulsants; Discrimination, Psychological; Flumazenil; gamma-Aminobutyric Acid; Humans; Isoniazid; Male; Pentobarbital; Pentylenetetrazole; Pyrazoles; Rats | 1985 |
Enhanced neuronal K+ conductance: a possible common mechanism for sedative-hypnotic drug action.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Calcium; Cattle; Ethanol; gamma-Aminobutyric Acid; Hippocampus; Hypnotics and Sedatives; In Vitro Techniques; Membrane Potentials; Neural Conduction; Pentobarbital; Potassium; Purkinje Cells; Tetrodotoxin | 1985 |
Excitatory and differential disinhibitory actions of acetylcholine in the lateral geniculate nucleus of the cat.
Topics: Acetylcholine; Action Potentials; Animals; Bicuculline; Cats; Cold Temperature; gamma-Aminobutyric Acid; Geniculate Bodies; Glutamates; Glutamic Acid; Neural Inhibition; Neurons; Pentobarbital; Retinal Ganglion Cells; Time Factors; Visual Cortex | 1986 |
Involvement of noradrenaline in potentiation of the head-twitch response by GABA-related drugs.
Topics: Adrenergic beta-Antagonists; Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Brain Chemistry; Catecholamines; Diazepam; Dopamine; Drug Synergism; gamma-Aminobutyric Acid; Male; Methoxydimethyltryptamines; Metoprolol; Mice; Muscimol; Norepinephrine; Pentobarbital; Picrotoxin; Stereotyped Behavior; Taurine | 1986 |
Benzodiazepine, beta-carboline, and barbiturate actions on GABA responses.
Topics: Animals; Anti-Anxiety Agents; Barbiturates; Bicuculline; Carbolines; Cells, Cultured; Clonazepam; Diazepam; gamma-Aminobutyric Acid; Membrane Potentials; Mice; Neurons; Nitrazepam; Pentobarbital; Phenobarbital; Picrotoxin; Receptors, GABA-A; Spinal Cord | 1986 |
Actions of pentobarbital on rat brain receptors expressed in Xenopus oocytes.
Topics: Animals; Brain; Chick Embryo; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; gamma-Aminobutyric Acid; Oocytes; Pentobarbital; Poly A; Rats; Receptors, GABA-A; Recombinant Proteins; RNA, Messenger; Xenopus laevis | 1986 |
Pharmacology of GABA receptors on skeletal muscle fibres of the locust (Schistocerca gregaria).
Topics: Amino Acids; Animals; Bicuculline; Dicarboxylic Acids; Electric Conductivity; GABA Antagonists; gamma-Aminobutyric Acid; Grasshoppers; Hydrogen-Ion Concentration; Muscles; Pentobarbital; Receptors, GABA-A | 1987 |
Pharmacologically induced changes in the latency of digastric reflexes in 1-7 day old rabbits.
Topics: Animals; Animals, Newborn; Bicuculline; Decerebrate State; Diazepam; Electromyography; gamma-Aminobutyric Acid; Pentobarbital; Picrotoxin; Rabbits; Reflex; Stomach; Strychnine; Synaptic Transmission | 1988 |
Changes of 36Cl- flux and 35S-TBPS binding induced by stress and gabaergic drugs.
Topics: Animals; Anti-Anxiety Agents; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Cell Membrane; Cerebral Cortex; Chlorides; Convulsants; gamma-Aminobutyric Acid; Male; Neurons; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stress, Physiological | 1988 |
Regulation of [3H]GABA release from strips of guinea pig urinary bladder.
Topics: Acetylcholine; Animals; Atropine; Baclofen; Bicuculline; Clonazepam; Clonidine; Female; gamma-Aminobutyric Acid; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Male; Muscimol; Pentobarbital; Phenylephrine; Pirenzepine; Potassium; Prazosin; Tritium; Urinary Bladder; Yohimbine | 1988 |
The GABAA receptor: new insights from single-channel recording.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; gamma-Aminobutyric Acid; Mice; Neurons; Organ Culture Techniques; Penicillin G; Pentobarbital; Receptors, GABA-A; Reference Values; Spinal Cord; Synapses | 1987 |
Acute barbiturate administration increases benzodiazepine receptor binding in vivo.
Topics: Animals; Anti-Anxiety Agents; Barbiturates; Brain Chemistry; Clonazepam; Flumazenil; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Male; Mice; Pentobarbital; Receptors, GABA-A | 1988 |
A role for gamma-aminobutyric acid (GABA) in the evolution of delayed neuronal death following ischemia.
Topics: Animals; gamma-Aminobutyric Acid; Gerbillinae; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Ischemic Attack, Transient; Pentobarbital; Time Factors | 1988 |
The extrasynaptic effect of gamma-aminobutyric acid and pentobarbital and the influence of temperature on the response of parallel fibres of the frog cerebellum in vitro.
Topics: Animals; Cerebellum; Electric Stimulation; gamma-Aminobutyric Acid; Nerve Fibers; Pentobarbital; Rana esculenta; Rana temporaria; Temperature | 1988 |
Comparison of the effects of diphenylbarbituric acid, phenobarbital, pentobarbital and secobarbital on GABA-mediated inhibition and benzodiazepine binding.
Topics: Animals; Benzodiazepines; Electrophysiology; Flunitrazepam; gamma-Aminobutyric Acid; Hippocampus; Male; Pentobarbital; Phenobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A; Secobarbital; Time Factors | 1985 |
Avermectin B1a modulation of gamma-aminobutyric acid/benzodiazepine receptor binding in mammalian brain.
Topics: Animals; Bicuculline; Brain; Cattle; Cell Membrane; Cerebral Cortex; Etazolate; gamma-Aminobutyric Acid; Isonicotinic Acids; Ivermectin; Lactones; Muscimol; Pentobarbital; Rats; Receptors, GABA-A | 1985 |
Involvement of a GABAergic mechanism in the anticonvulsant effect of pentobarbital against maximal electroshock-induced seizures in rats.
Topics: Animals; Anticonvulsants; Benzodiazepinones; Bicuculline; Drug Interactions; Electroshock; Ethanol; Flumazenil; GABA Antagonists; gamma-Aminobutyric Acid; Male; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures; Sleep | 1985 |
Postsynaptic firing during repetitive stimulation is required for long-term potentiation in hippocampus.
Topics: Action Potentials; Animals; Electric Stimulation; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Neuronal Plasticity; Pentobarbital; Rats; Rats, Inbred Strains; Synapses; Synaptic Transmission; Tetrodotoxin | 1985 |
gamma-Aminobutyric acid partly mediates the pentobarbitone depression of synaptic excitation in the guinea-pig olfactory cortex in vitro.
Topics: Animals; Bicuculline; Drug Interactions; Female; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Limbic System; Male; Membrane Potentials; Olfactory Pathways; Pentobarbital; Picrotoxin; Synapses; Synaptic Transmission | 1985 |
Effect of picrotoxinin on benzodiazepine receptor binding.
Topics: Animals; Brain; Cerebellum; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Male; Membranes; Mice; Pentobarbital; Picrotoxin; Receptors, GABA-A; Sesterterpenes | 1985 |
Aging: effect on the interaction of ethanol and pentobarbital with the benzodiazepine-GABA receptor-ionophore complex.
Topics: Aging; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Ethanol; Flunitrazepam; gamma-Aminobutyric Acid; Ionophores; Kinetics; Male; Pentobarbital; Rats; Rats, Inbred F344; Receptors, GABA-A; Temperature | 1985 |
Differential sensitivity of "central" and "peripheral" type benzodiazepine receptors to phospholipase A2.
Topics: Animals; Benzodiazepinones; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carbolines; Cerebral Cortex; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Kidney; Male; Myocardium; Pentobarbital; Phospholipases; Phospholipases A; Phospholipases A2; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1986 |
Regional difference in brain benzodiazepine receptor carbohydrates.
Topics: Acetylglucosaminidase; Animals; Asparagine; Benzodiazepinones; Brain Chemistry; Carbohydrates; Electrophoresis, Polyacrylamide Gel; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Male; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Molecular Weight; Muscimol; Neuraminidase; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sialic Acids; Tritium | 1986 |
Anticonvulsant profile of drugs which facilitate GABAergic transmission on convulsions mediated by a GABAergic mechanism.
Topics: Animals; Anticonvulsants; Convulsants; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; gamma-Aminobutyric Acid; Male; Pentobarbital; Rats; Rats, Inbred Strains; Seizures; Synaptic Transmission | 1986 |
Effect of ethanol on the binding of 35S-T-butylbicyclophosphorothionate to mouse brain membranes.
Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Cell Membrane; Cerebellum; Cerebral Cortex; Ethanol; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred C57BL; Pentobarbital; Picrotoxin; Receptors, GABA-A | 1986 |
Caprolactam-barbiturate interaction at the GABAA receptor complex in the guinea-pig intestine.
Topics: Animals; Azepines; Barbiturates; Caprolactam; Female; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; Male; Muscle Contraction; Muscle, Smooth; Pentobarbital; Receptors, GABA-A | 1986 |
Midazolam cue in rats: effects of Ro 15-1788 and picrotoxin.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Discrimination, Psychological; Dose-Response Relationship, Drug; Flumazenil; gamma-Aminobutyric Acid; Male; Midazolam; Nicotine; Pentobarbital; Picrotoxin; Rats; Receptors, GABA-A | 1986 |
Modulation of the brain aversive system by GABAergic and serotonergic mechanisms.
Topics: Animals; Avoidance Learning; Benzodiazepines; Cerebral Ventricles; Chlordiazepoxide; Drug Interactions; gamma-Aminobutyric Acid; Isonicotinic Acids; Midazolam; Muscimol; Pentobarbital; Periaqueductal Gray; Rats; Receptors, GABA-A; Serotonin | 1986 |
The effects of drugs acting at the GABAA-receptor/ionophore after chemical kindling with the benzodiazepine receptor ligand FG 7142.
Topics: Animals; Bicuculline; Body Temperature; Carbolines; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Mice; Muscimol; Pentobarbital; Pentylenetetrazole; Picrotoxin; Receptors, GABA-A; Seizures; Time Factors | 1986 |
The enhancement of diazepam and muscimol binding by pentobarbital and (+)-etomidate: size of the molecular arrangement estimated by electron irradiation inactivation of rat cortex.
Topics: Animals; Cerebral Cortex; Diazepam; Etomidate; gamma-Aminobutyric Acid; In Vitro Techniques; Molecular Weight; Muscimol; Pentobarbital; Rats; Receptors, GABA-A | 1986 |
Responses to GABA by isolated insect neuronal somata: pharmacology and modulation by a benzodiazepine and a barbiturate.
Topics: Animals; Chemical Phenomena; Chemistry; Flunitrazepam; gamma-Aminobutyric Acid; Ganglia; Grasshoppers; In Vitro Techniques; Pentobarbital; Receptors, GABA-A; Species Specificity; Vertebrates | 1987 |
Barbiturate-induced inhibition of a spinal nociceptive reflex: role of GABA mechanisms and descending modulation.
Topics: Analgesics; Animals; Depression, Chemical; gamma-Aminobutyric Acid; Male; Pain; Pentobarbital; Rats; Rats, Inbred Strains; Reflex; Spinal Cord; Synaptic Transmission | 1987 |
Adaptation of the GABAA-receptor complex in rat brain during chronic elevation of GABA by ethanolamine O-sulphate.
Topics: 4-Aminobutyrate Transaminase; Animals; Brain Chemistry; Ethanolamines; Flurazepam; gamma-Aminobutyric Acid; Muscimol; Nipecotic Acids; Pentobarbital; Picrotoxin; Potassium; Proline; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1987 |
gamma-Aminobutyric acid receptor binding in fresh mouse brain membranes at 22 degrees C: ligand-induced changes in affinity.
Topics: Allosteric Regulation; Animals; Brain; Cell Membrane; gamma-Aminobutyric Acid; Kinetics; Ligands; Mice; Microsomes; Mitochondria; Muscimol; Pentobarbital; Receptors, GABA-A; Temperature | 1987 |
Neurochemical and pharmacologic investigations of punished behavior.
Topics: Animals; Brain; Dopamine; gamma-Aminobutyric Acid; Male; Organ Specificity; Pentobarbital; Punishment; Rats; Rats, Inbred F344; Reinforcement, Psychology; Serotonin | 1986 |
Effect of RO 15-1788 on diazepam, GABA & pentobarbitone induced EEG changes in rabbits.
Topics: Animals; Cerebral Cortex; Diazepam; Electroencephalography; Electromyography; Female; Flumazenil; gamma-Aminobutyric Acid; Male; Pentobarbital; Rabbits | 1986 |
Neurosteroid pregnenolone sulfate antagonizes electrophysiological responses to GABA in neurons.
Topics: Action Potentials; Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Cerebral Cortex; Flumazenil; gamma-Aminobutyric Acid; Pentobarbital; Pregnenolone; Rats; Steroids | 1988 |
Comparison between pentobarbital- and muscimol-induced feeding in satiated sheep.
Topics: Aminocaproates; Animals; Calcium; Eating; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Muscimol; Pentobarbital; Picrotoxin; Sheep; Sodium; Vigabatrin | 1988 |
Pentobarbital augments serotonin-mediated inhibition of cerebellar Purkinje cells.
Topics: Action Potentials; Animals; gamma-Aminobutyric Acid; Male; Neural Inhibition; Pentobarbital; Pentylenetetrazole; Picrotoxin; Purkinje Cells; Rats; Rats, Inbred Strains; Serotonin | 1988 |
Specific effects of punishment on amino acids turnover in discrete rat brain regions.
Topics: Amino Acids; Animals; Anxiety; Aspartic Acid; Behavior, Animal; Brain; Brain Chemistry; Conflict, Psychological; gamma-Aminobutyric Acid; Glutamates; Male; Pentobarbital; Punishment; Rats; Rats, Inbred F344 | 1988 |
Potentiation of the anticonflict effects of diazepam, but not pentobarbital and phenobarbital, by aminooxyacetic acid (AOAA).
Topics: Acetates; Aminooxyacetic Acid; Animals; Anxiety; Behavior, Animal; Conflict, Psychological; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Female; gamma-Aminobutyric Acid; Pentobarbital; Phenobarbital; Rats; Rats, Inbred Strains | 1988 |
A comparison of the effects of midazolam and pentobarbital on the dose-response of GABA-gated Cl- influx in rat brain microsacs.
Topics: Animals; Chlorides; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Ions; Male; Midazolam; Pentobarbital; Rats; Rats, Inbred Strains | 1988 |
[35S]TBPS binding to membranes of the female sex organs: modulation of chloride ionophore by GABA and pentobarbital.
Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Chlorides; Convulsants; Fallopian Tubes; Female; gamma-Aminobutyric Acid; Genitalia, Female; In Vitro Techniques; Ionophores; Membranes; Ovary; Pentobarbital; Rats; Rats, Inbred Strains; Uterus | 1988 |
Possible involvement of the central GABAergic system in pentobarbital-stimulated gastric acid secretion in the perfused rat stomach preparation.
Topics: 3-Mercaptopropionic Acid; Anesthesia; Animals; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Gastric Acid; Gastric Mucosa; In Vitro Techniques; Male; Pentobarbital; Pentylenetetrazole; Perfusion; Picrotoxin; Rats; Rats, Inbred Strains; Urethane | 1988 |
Kinetic properties of the pentobarbitone-gated chloride current in frog sensory neurones.
Topics: Animals; Bicuculline; Chlorides; Dose-Response Relationship, Drug; Electrophysiology; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Neurons, Afferent; Pentobarbital; Picrotoxin; Rana catesbeiana | 1987 |
Effects of anticonvulsant and convulsant gamma-butyrolactones and thiobutyrolactones on GABA-mediated chloride uptake.
Topics: 4-Butyrolactone; Animals; Anticonvulsants; Cerebral Cortex; Chlorides; Convulsants; Female; Furans; gamma-Aminobutyric Acid; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Sesterterpenes; Structure-Activity Relationship | 1987 |
Foot shock stress decreases chloride efflux from rat brain synaptoneurosomes.
Topics: Animals; Brain; Chlorides; Electroshock; gamma-Aminobutyric Acid; Male; Muscimol; Pentobarbital; Rats; Rats, Inbred Strains; Stress, Psychological; Synaptosomes | 1987 |
Effects of pentobarbital and flurazepam on respiratory neurons in undrugged cats.
Topics: Animals; Cats; Decerebrate State; Electrophysiology; Flurazepam; gamma-Aminobutyric Acid; Neurons; Pentobarbital; Respiratory System | 1987 |
Effects of diazepam, pentobarbital, phenytoin and pentylenetetrazol on hippocampal paired-pulse inhibition in vivo.
Topics: Action Potentials; Animals; Behavior, Animal; Diazepam; Electroshock; gamma-Aminobutyric Acid; Hippocampus; Injections, Intraperitoneal; Male; Neural Inhibition; Pentobarbital; Pentylenetetrazole; Phenytoin; Rats; Rats, Inbred Strains; Seizures | 1986 |
Facilitation of recurrent inhibition in rat hippocampus by barbiturate and related nonbarbiturate depressant drugs.
Topics: Animals; Barbiturates; Central Nervous System Depressants; Etomidate; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Mephobarbital; Neural Inhibition; Pentobarbital; Phenobarbital; Rats; Rats, Inbred Strains; Stereoisomerism | 1986 |
Inhibitory circuitry in the ventral cochlear nucleus is probably mediated by glycine.
Topics: Animals; Cochlear Nerve; Electric Conductivity; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Ions; Mice; Mice, Inbred Strains; Neural Inhibition; Pentobarbital; Strychnine | 1986 |
The effects of anaesthetics and high pressure on the responses of the rat superior cervical ganglion in vitro.
Topics: Action Potentials; Air Pressure; Anesthetics; Animals; Atmospheric Pressure; gamma-Aminobutyric Acid; Ganglia, Sympathetic; Helium; Male; Nitrogen; Nitrous Oxide; Pentobarbital; Quaternary Ammonium Compounds; Rats; Rats, Inbred Strains; Temperature | 1986 |
GABAergic influences on barbital withdrawal induced convulsions.
Topics: Animals; Barbital; Barbiturates; Corpus Striatum; gamma-Aminobutyric Acid; Male; Pentobarbital; Rats; Rats, Inbred Strains; Seizures; Substance Withdrawal Syndrome; Time Factors | 1986 |
Facilitatory action of etomidate and pentobarbital on recurrent inhibition in rat hippocampal pyramidal neurons.
Topics: Action Potentials; Animals; Etomidate; gamma-Aminobutyric Acid; Hippocampus; Male; Neurons; Pentobarbital; Pyramidal Tracts; Rats; Rats, Inbred Strains; Synapses | 1986 |
Gamma-aminobutyric acid and alcohol actions: neurochemical studies of long sleep and short sleep mice.
Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cerebellum; Chlorides; Diencephalon; Drug Synergism; Ethanol; Female; gamma-Aminobutyric Acid; Hippocampus; Mice; Muscimol; Pentobarbital; Sleep; Telencephalon | 1986 |
Studies of the role of gamma-aminobutyric acid in the hypothalamic control of feed intake in sheep.
Topics: Animals; Bicuculline; Brain; Eating; gamma-Aminobutyric Acid; Hypothalamus; Male; Muscimol; Pentobarbital; Picrotoxin; Sheep | 1985 |
Fast recording ion specific microelectrodes: their use in pharmacological studies in the CNS.
Topics: Acetylcholine; Animals; Bucladesine; Cats; Central Nervous System; Cerebral Cortex; Chlorides; Electric Conductivity; Electric Stimulation; Extracellular Space; gamma-Aminobutyric Acid; Geniculate Bodies; Glutamates; Ion Exchange; Iontophoresis; Microelectrodes; Neurons; Norepinephrine; Pentobarbital; Phenytoin; Potassium; Potassium Chloride; Quaternary Ammonium Compounds; Tracheotomy | 1974 |
The effect of barbiturates on (3H)GABA transport in rat cerebral cortex slices.
Topics: Aminobutyrates; Amobarbital; Animals; Binding, Competitive; Biological Transport; Cell Membrane; Cerebral Cortex; Depression, Chemical; Dose-Response Relationship, Drug; Drug Synergism; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Hexobarbital; Male; Ouabain; Pentobarbital; Phenobarbital; Potassium; Rats; Sodium; Stimulation, Chemical; Time Factors; Tritium | 1974 |
Organization of visual cortex primary response.
Topics: Animals; Atropine; Cats; Chloralose; Chlorpromazine; Electrophysiology; Epinephrine; gamma-Aminobutyric Acid; Microelectrodes; Neurons; Pentobarbital; Physostigmine; Potassium Chloride; Reaction Time; Visual Cortex | 1973 |
Analysis of the effects on body temperature of intracerebroventricular injection in anaesthetized dogs of gamma-aminobutyric acid.
Topics: Acetylcholine; Aminobutyrates; Animals; Body Temperature; Cerebral Ventricles; Dogs; Epinephrine; Female; gamma-Aminobutyric Acid; Hexamethonium Compounds; Histamine; Injections; Isoproterenol; Lysergic Acid Diethylamide; Male; Morphine; Norepinephrine; Pentobarbital; Perfusion; Phenoxybenzamine; Phentolamine; Propranolol; Prostaglandins; Pyrilamine; Reserpine; Salicylates; Scopolamine; Serotonin; Time Factors | 1974 |
Effects of acute and chronic pentobarbitone on the gamma-aminobutyric acid system in rat brain.
Topics: Aminobutyrates; Animals; Brain; Carboxy-Lyases; gamma-Aminobutyric Acid; Glutamates; Pentobarbital; Pyridoxal Phosphate; Rats; Time Factors; Transaminases | 1974 |
Effect of pentobarbital on uptake and release of [3H]GABA and [14C]glutamate by brain slices.
Topics: Aminobutyrates; Animals; Brain; Cell Membrane; Depression, Chemical; gamma-Aminobutyric Acid; Glutamates; In Vitro Techniques; Pentobarbital; Rats | 1974 |
Differential interactions of GABA agonists, depressant and convulsant drugs with [35S]-t-butylbicyclophosphorothionate binding sites in cortex and cerebellum.
Topics: Animals; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Central Nervous System Depressants; Cerebellum; Cerebral Cortex; Convulsants; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Male; Mitochondria; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Synaptic Transmission; Thiocyanates | 1984 |
Chemically activated channels in muscle and spinal cord.
Topics: Acetylcholine; Animals; Chlorides; gamma-Aminobutyric Acid; Ion Channels; Kinetics; Membrane Potentials; Muscimol; Neuromuscular Junction; Pentobarbital; Receptors, Cholinergic; Receptors, GABA-A; Spinal Cord; Stimulation, Chemical; Synaptic Transmission | 1984 |
Interaction of penicillin and pentobarbital with inhibitory synaptic mechanisms in neocortex.
Topics: Animals; Cerebral Cortex; Drug Interactions; Evoked Potentials; gamma-Aminobutyric Acid; Neural Inhibition; Penicillins; Pentobarbital; Rats; Rats, Inbred Strains; Synaptic Transmission | 1984 |
Some barbiturates enhance the effect of muscimol on dopamine turnover in the rat retina.
Topics: Animals; Barbital; Barbiturates; Convulsants; Dopamine; Drug Synergism; GABA Antagonists; gamma-Aminobutyric Acid; Light; Male; Methyltyrosines; Muscimol; Oxazoles; Pentobarbital; Phenobarbital; Picrotoxin; Rats; Retina; Sesterterpenes | 1980 |
Effects of barbiturates on inhibitory and excitatory responses to applied neurotransmitters in Aplysia.
Topics: Acetylcholine; Action Potentials; Animals; Aplysia; Barbiturates; Chlorides; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; In Vitro Techniques; Neural Inhibition; Neurons; Neurotransmitter Agents; Pentobarbital; Phenobarbital; Potassium; Sodium | 1980 |
Effects of pentobarbital and Ca2+ on the resting and K+-stimulated release of several endogenous neurotransmitters from rat midbrain slices.
Topics: Acetylcholine; Amino Acids; Animals; Calcium; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Male; Mesencephalon; Neurotransmitter Agents; Pentobarbital; Potassium; Rats; Serotonin; Time Factors | 1980 |
Blockade of methamphetamine-induced depression of tyrosine hydroxylase by GABA transaminase inhibitors.
Topics: 4-Aminobutyrate Transaminase; Animals; Corpus Striatum; Diazepam; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Methamphetamine; Pentobarbital; Rats; Substantia Nigra; Transaminases; Tyrosine 3-Monooxygenase | 1980 |
The benzodiazepine--GABA--chloride ionophore receptor complex: common site of minor tranquilizer action.
Topics: Animals; Anti-Anxiety Agents; Cattle; Cerebral Cortex; Chlorides; Diazepam; gamma-Aminobutyric Acid; Male; Meprobamate; Pentobarbital; Rats; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Tetrazoles | 1981 |
Biological substrates of anxiety: benzodiazepine receptors and endogenous ligands.
Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Brain; Carbolines; Chlorides; Etazolate; Ethanol; gamma-Aminobutyric Acid; Humans; Molecular Weight; Niacinamide; Pentobarbital; Purines; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A | 1982 |
Comparison of the kinetics of [3H]diazepam and [3H]flunitrazepam binding to cortical synaptosomal membranes.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Cerebral Cortex; Diazepam; Filtration; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Male; Pentobarbital; Rats; Rats, Inbred Strains; Sodium Chloride; Synaptic Membranes | 1982 |
In vitro and in vivo effects of pentobarbitone sodium.
Topics: Anesthetics; Animals; Cats; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Mice; Pentobarbital; Rats; Therapeutic Equivalency | 1982 |
GABA and flunitrazepam binding to neuroblastoma cell membranes--effects of growth conditions, ethanol and pentobarbital.
Topics: Anti-Anxiety Agents; Binding, Competitive; Cell Line; Culture Media; Culture Techniques; Ethanol; Flunitrazepam; gamma-Aminobutyric Acid; Humans; Kinetics; Neuroblastoma; Pentobarbital; Receptors, Cell Surface; Receptors, GABA-A | 1982 |
Characterization of flunitrazepam and beta-carboline high affinity binding in bovine pineal gland.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Binding Sites; Carbolines; Cattle; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Indoles; Kinetics; Pentobarbital; Pineal Gland; Rats; Species Specificity | 1983 |
Rat hippocampal neurons in culture: voltage-clamp analysis of inhibitory synaptic connections.
Topics: Animals; Chlorides; Culture Techniques; Diazepam; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; Interneurons; Ion Channels; Kinetics; Membrane Potentials; Neural Inhibition; Neurons; Pentobarbital; Picrotoxin; Rats; Reaction Time; Synapses | 1984 |
Regular firing patterns of suprachiasmatic neurons maintained in vitro.
Topics: Action Potentials; Animals; Culture Techniques; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Pentobarbital; Rats; Rats, Inbred Strains; Suprachiasmatic Nucleus; Urethane | 1984 |
The effects of pentobarbital and related compounds on frog motoneurons.
Topics: Amino Acids; Animals; Anura; Bicuculline; Chloralose; Chlordiazepoxide; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Motor Neurons; Muscimol; Pentobarbital; Phenobarbital; Phenytoin; Picrotoxin; Spinal Cord; Strychnine; Synaptic Transmission | 1980 |
(-)Pentobarbital opens ion channels of long duration in cultured mouse spinal neurons.
Topics: Animals; Cell Membrane; Cells, Cultured; gamma-Aminobutyric Acid; Ion Channels; Membrane Potentials; Mice; Neurons; Pentobarbital; Spinal Cord | 1980 |
Pentobarbital potentiates GABA-enhanced [3H]-diazepam binding to benzodiazepine receptors.
Topics: Animals; Benzodiazepines; Chlorides; Diazepam; Drug Synergism; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Male; Pentobarbital; Rats; Receptors, Drug; Tritium | 1980 |
Pentobarbital: dual actions to increase brain benzodiazepine receptor affinity.
Topics: Animals; Cerebral Cortex; Chlorides; Diazepam; gamma-Aminobutyric Acid; Male; Pentobarbital; Rats; Receptors, Drug; Receptors, GABA-A; Stimulation, Chemical | 1981 |
A comparison of the effects of pentobarbital and diphenylhydantoin on the GABA sensitivity and excitability of adult sensory ganglion cells.
Topics: Animals; Dose-Response Relationship, Drug; Evoked Potentials; gamma-Aminobutyric Acid; Ganglia, Spinal; Ion Channels; Pentobarbital; Phenytoin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Tetrodotoxin; Veratridine | 1981 |
Barbiturate enhancement of GABA-mediated inhibition and activation of chloride ion conductance: correlation with anticonvulsant and anesthetic actions.
Topics: Animals; Bicuculline; Chlorides; Dose-Response Relationship, Drug; Evoked Potentials; gamma-Aminobutyric Acid; Ion Channels; Mice; Neural Inhibition; Neurons; Pentobarbital; Phenobarbital; Spinal Cord | 1981 |
Pentobarbitone slows the dissociation of GABA from rat brain synaptosomal binding sites.
Topics: Animals; Brain; gamma-Aminobutyric Acid; Intracellular Membranes; Kinetics; Pentobarbital; Rats; Receptors, Cell Surface; Receptors, GABA-A; Synaptosomes | 1981 |
A comparison of the actions of pentobarbitone and etomidate on [3H]GABA binding to crude synaptosomal rat brain membranes.
Topics: Animals; Brain; Etomidate; gamma-Aminobutyric Acid; Imidazoles; Intracellular Membranes; Kinetics; Pentobarbital; Rats; Receptors, Cell Surface; Receptors, GABA-A; Synaptosomes | 1981 |
Chloride-dependent stimulation of GABA and benzodiazepine receptor binding by pentobarbital.
Topics: Animals; Brain; Cattle; Chlorides; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Pentobarbital; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A | 1981 |
Dual action of pentobarbitone on GABA binding: role of binding site integrity.
Topics: Animals; Brain; Diazepam; gamma-Aminobutyric Acid; Intracellular Membranes; Kinetics; Pentobarbital; Rats; Receptors, Cell Surface; Receptors, GABA-A; Synaptosomes | 1981 |
Pentobarbitone interference with inhibitory synaptic transmission in crayfish stretch receptor neurones.
Topics: Animals; Astacoidea; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Mechanoreceptors; Neural Inhibition; Pentobarbital; Picrotoxin; Synapses; Synaptic Transmission | 1981 |
Barbiturate and GABA receptors coupled to benzodiazepine receptors in rat hippocampal formation: a radiohistochemical study.
Topics: Animals; Autoradiography; Flunitrazepam; gamma-Aminobutyric Acid; Hippocampus; Histocytochemistry; Male; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Receptors, Neurotransmitter | 1981 |
Diazepam and (--)-pentobarbital: fluctuation analysis reveals different mechanisms for potentiation of gamma-aminobutyric acid responses in cultured central neurons.
Topics: Animals; Cells, Cultured; Diazepam; Embryo, Mammalian; gamma-Aminobutyric Acid; Ion Channels; Membrane Potentials; Mice; Mice, Inbred C57BL; Neurons; Pentobarbital; Spinal Cord | 1981 |
Acute and chronic effects of pentobarbital in relation to postsynaptic GABA receptors: a study with muscimol.
Topics: Animals; Brain; Drug Tolerance; gamma-Aminobutyric Acid; Humans; Male; Mice; Mice, Inbred ICR; Muscimol; Oxazoles; Pentobarbital; Receptors, Cell Surface; Receptors, GABA-A; Sleep; Substance Withdrawal Syndrome; Synaptic Membranes | 1982 |
Binding of a radiolabeled triazolopyridazine to a subtype of benzodiazepine receptor in the rat cerebellum.
Topics: Animals; Anions; Cerebellum; Flunitrazepam; gamma-Aminobutyric Acid; Male; Pentobarbital; Pyrazoles; Pyridazines; Rats; Rats, Inbred Strains; Receptors, Drug; Receptors, GABA-A | 1982 |
Single channel currents activated by gamma-aminobutyric acid, muscimol, and (-)-pentobarbital in cultured mouse spinal neurons.
Topics: Animals; Cells, Cultured; Embryo, Mammalian; gamma-Aminobutyric Acid; Ion Channels; Kinetics; Mice; Muscimol; Neurons; Oxazoles; Pentobarbital; Spinal Cord | 1982 |
A comparative study of avermectin B1a and other modulators of the gamma-aminobutyric acid receptor . chloride ion channel complex.
Topics: Animals; Anthelmintics; Benzodiazepines; Brain; Chlorides; Clonazepam; gamma-Aminobutyric Acid; Ion Channels; Ivermectin; Lactones; Male; Pentobarbital; Picrotoxin; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Synaptic Membranes | 1982 |
Differential effects of sedative and anticonvulsant barbiturates on specific [3H]GABA binding to membrane preparations from rat brain cortex.
Topics: Animals; Anticonvulsants; Barbiturates; Brain; gamma-Aminobutyric Acid; Hypnotics and Sedatives; In Vitro Techniques; Kinetics; Male; Membranes; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Synaptosomes | 1982 |
Anisatin modulation of GABA- and pentobarbital-induced enhancement of diazepam binding in rat brain.
Topics: Animals; Brain; Diazepam; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Lactones; Male; Neurotoxins; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Sesquiterpenes; Sesterterpenes; Spiro Compounds | 1982 |
Effect of barbiturates on the GABA receptor of cat primary afferent neurones.
Topics: Action Potentials; Animals; Cats; Electric Conductivity; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Neurons, Afferent; Pentobarbital; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter; Thiopental | 1982 |
Multiple excitability functions in cultured mouse spinal neurones.
Topics: Action Potentials; Animals; Cells, Cultured; Chlorides; Diazepam; gamma-Aminobutyric Acid; Ion Channels; Kinetics; Membrane Potentials; Mice; Neurons; Pentobarbital; Spinal Cord | 1982 |
Heterogeneity of benzodiazepine receptor interactions with gamma-aminobutyric acid and barbiturate receptor sites.
Topics: Animals; Bicuculline; Binding Sites; Brain; Diazepam; gamma-Aminobutyric Acid; Kinetics; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter; Tissue Distribution | 1983 |
Chronic pentobarbital diminishes GABA- and pentobarbital-enhanced [3H]diazepam binding to benzodiazepine receptors.
Topics: Animals; Cells, Cultured; Chick Embryo; Chlorides; Diazepam; gamma-Aminobutyric Acid; Pentobarbital; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Enhancement of GABA binding by pentobarbitone.
Topics: Animals; Brain; Cell Membrane; gamma-Aminobutyric Acid; Pentobarbital; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Sesterterpenes; Synaptosomes | 1980 |
Kindled seizures result in decreased responsiveness of benzodiazepine receptors to gamma-aminobutyric acid (GABA).
Topics: Animals; Flunitrazepam; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Seizures; Sodium Chloride | 1983 |
Enhancement of diazepam and gamma-aminobutyric acid binding by (+)etomidate and pentobarbital.
Topics: Animals; Cell Membrane; Cerebellum; Cerebral Cortex; Diazepam; Etomidate; gamma-Aminobutyric Acid; Imidazoles; Kinetics; Male; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Central gamma-aminobutyric acid involvement in blood pressure control.
Topics: Animals; Bicuculline; Blood Pressure; Brain; Cats; Disease Models, Animal; gamma-Aminobutyric Acid; Guinea Pigs; Hypertension; Medulla Oblongata; Pentobarbital; Picrotoxin; Receptors, Cell Surface; Receptors, GABA-A; Respiration | 1984 |
Actions of pentobarbitone and derivatives with modified 5-butyl substituents on GABA and diazepam binding to rat brain synaptosomal membranes.
Topics: Animals; Brain; Diazepam; gamma-Aminobutyric Acid; Intracellular Membranes; Kinetics; Male; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Structure-Activity Relationship; Synaptosomes | 1983 |
A gamma-aminobutyric acid/benzodiazepine receptor complex from bovine cerebral cortex. Improved purification with preservation of regulatory sites and their interactions.
Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cerebral Cortex; Cholic Acids; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Methods; Muscimol; Pentobarbital; Receptors, Cell Surface; Receptors, GABA-A; Solubility | 1984 |
gamma-Aminobutyric acid activation of 36Cl- flux in rat hippocampal slices and its potentiation by barbiturates.
Topics: Animals; Chlorides; Culture Techniques; Female; gamma-Aminobutyric Acid; Hippocampus; Ion Channels; Male; Neural Inhibition; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Secobarbital; Stimulation, Chemical; Synapses | 1984 |
[3H]diazepam binding sites on chick neurons in primary culture.
Topics: Animals; Benzodiazepinones; Binding Sites; Binding, Competitive; Cells, Cultured; Chick Embryo; Clonazepam; Diazepam; gamma-Aminobutyric Acid; Neurons; Pentobarbital; Telencephalon | 1983 |
Binding characteristics and interactions of depressant drugs with [35S]t-butylbicyclophosphorothionate, a ligand that binds to the picrotoxinin site.
Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Convulsants; Diazepam; Etomidate; gamma-Aminobutyric Acid; Male; Membranes; Pentobarbital; Picrotoxin; Psychotropic Drugs; Rats; Rats, Inbred Strains; Sesterterpenes | 1984 |
Discriminative stimulus effects of pentobarbital in pigeons.
Topics: Animals; Baclofen; Bemegride; Columbidae; Ethanol; gamma-Aminobutyric Acid; Muscimol; Pentobarbital; Prejudice | 1980 |
Pentobarbital causes cardiorespiratory depression by interacting with a GABAergic system at the ventral surface of the medulla.
Topics: Animals; Bicuculline; Blood Pressure; Cats; gamma-Aminobutyric Acid; Heart Rate; Medulla Oblongata; Pentobarbital; Respiration; Tidal Volume | 1983 |
Effects of barbiturates and ethanol on muscimol-induced release of [3H]-D-aspartate from rodent cerebellum.
Topics: Animals; Aspartic Acid; Cerebellum; Ethanol; gamma-Aminobutyric Acid; Kinetics; Male; Muscimol; Oxazoles; Pentobarbital; Potassium; Rats; Rats, Inbred Strains; Synaptosomes; Tritium | 1983 |
Feed-forward dendritic inhibition in rat hippocampal pyramidal cells studied in vitro.
Topics: Animals; Dendrites; Diazepam; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Neural Inhibition; Pentobarbital; Phenobarbital; Pyramidal Tracts; Rats; Synapses; Temperature | 1982 |
Pharmacological evidence for two kinds of GABA receptor on rat hippocampal pyramidal cells studied in vitro.
Topics: Animals; Bicuculline; Dendrites; Diazepam; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Isoxazoles; Membrane Potentials; Penicillins; Pentobarbital; Pyramidal Tracts; Rats; Receptors, Drug | 1982 |
Variations in the kinetic pattern of astrocytic gamma-aminobutyric acid uptake when inhibited by different barbiturates.
Topics: Animals; Astrocytes; Barbiturates; Cells, Cultured; gamma-Aminobutyric Acid; Kinetics; Mice; Pentobarbital; Phenobarbital | 1982 |
Dissimilar influences of some injectable anaesthetics on the responses of reticulo-spinal neurones to inhibitory transmitters in the lamprey.
Topics: Anesthetics; Animals; gamma-Aminobutyric Acid; Glycine; Ketamine; Lampreys; Medulla Oblongata; Neurons; Pentobarbital; Pregnanediones | 1982 |
Cellular bases of barbiturate and phenytoin anticonvulsant drug action.
Topics: Animals; Barbiturates; Bicuculline; Drug Interactions; gamma-Aminobutyric Acid; In Vitro Techniques; Mice; Neurons; Pentobarbital; Phenobarbital; Phenytoin; Synapses | 1982 |
Anesthetic barbiturates in refractory status epilepticus.
Topics: Adult; Anticonvulsants; Brain; Female; gamma-Aminobutyric Acid; Glutamates; Humans; Injections, Intravenous; Male; Middle Aged; Oxygen Consumption; Pentobarbital; Seizures; Status Epilepticus; Thiopental | 1980 |
Inhibitory amino acids and periodic discharges of respiratory neurons in the medulla of the cat.
Topics: Amino Acids; Anesthesia; Animals; Cats; gamma-Aminobutyric Acid; Glycine; Medulla Oblongata; Neurons; Pentobarbital; Respiration; Respiratory System; Time Factors | 1981 |
Direct action of pentobarbitone in potentiating the responses to GABA of rat dorsal root ganglion neurones in vitro.
Topics: Action Potentials; Animals; Bicuculline; Drug Synergism; gamma-Aminobutyric Acid; Ganglia, Spinal; Membrane Potentials; Neurons; Pentobarbital; Picrotoxin; Rats | 1981 |
Pharmacological investigation of gamma aminobutyric acid (GABA) and the development of amygdala-kindled seizures in the rat.
Topics: 3-Mercaptopropionic Acid; 4-Aminobutyrate Transaminase; Aminocaproates; Amygdala; Animals; Bicuculline; gamma-Aminobutyric Acid; Imidazoles; Kindling, Neurologic; Male; Pentobarbital; Picrotoxin; Rats; Seizures; Vigabatrin | 1981 |
Electrophysiological analysis of inhibitory synaptic mechanisms in the preoptic area of the rat.
Topics: Animals; Evoked Potentials; Female; gamma-Aminobutyric Acid; Hypothalamus; Interneurons; Neural Inhibition; Neurons; Neurotoxins; Pentobarbital; Preoptic Area; Rats; Rats, Inbred Strains; Synapses | 1981 |
Anesthetic-dependent excitability changes in the hypothalamic ventromedial nucleus of the rat.
Topics: Amygdala; Animals; Electric Stimulation; Evoked Potentials; Female; gamma-Aminobutyric Acid; Hypothalamus; Hypothalamus, Middle; Neural Inhibition; Neural Pathways; Neurons; Pentobarbital; Picrotoxin; Rats; Urethane | 1980 |
Release of endogenous amino acid neurotransmitter candidates from rat olfactory cortex slices: possible regulatory mechanisms and the effects of pentobarbitone.
Topics: Animals; Aspartic Acid; Dose-Response Relationship, Drug; Electric Stimulation; gamma-Aminobutyric Acid; Male; Muscimol; Olfactory Bulb; Pentobarbital; Picrotoxin; Rats; Taurine | 1980 |
Spontaneous inhibitory post-synaptic potentials in hippocampus: mechanism for tonic inhibition.
Topics: Animals; Bicuculline; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Pentobarbital; Rats; Synapses; Tetrodotoxin | 1980 |
Effects of pentobarbitone on the synaptically evoked release of the amino acid neurotransmitter candidates aspartate and GABA from rat olfactory cortex.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Electric Stimulation; gamma-Aminobutyric Acid; Olfactory Pathways; Pentobarbital; Picrotoxin; Rats; Synapses; Taurine | 1981 |
A barbiturate evoked intensification of postsynaptic inhibition in the preoptic ovulatory trigger region of the hypothalamus.
Topics: Animals; Barbiturates; Female; gamma-Aminobutyric Acid; Hypothalamus; Methohexital; Neural Inhibition; Neurons; Ovulation; Pentobarbital; Preoptic Area; Rats; Synapses; Thiopental | 1981 |
GABAA receptor needs two homologous domains of the beta-subunit for activation by GABA but not by pentobarbital.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cell Membrane; DNA Mutational Analysis; Female; gamma-Aminobutyric Acid; Ion Channels; Kinetics; Macromolecular Substances; Molecular Sequence Data; Muscimol; Mutagenesis, Site-Directed; Oocytes; Pentobarbital; Point Mutation; Rats; Receptors, GABA-A; Xenopus laevis | 1993 |
[Changes in GABAA/benzodiazepine receptor complex function in the pentobarbital-dependent rat].
Topics: Animals; Binding Sites; Brain; Down-Regulation; Drug Tolerance; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Pentobarbital; Rats; Rats, Inbred Lew; Receptors, GABA; Receptors, GABA-A; Substance-Related Disorders | 1995 |
[Changes in GABAA/benzodiazepine receptor complex function in the pentobarbital-dependent rat. II: Strain differences between Lewis and Wistar-Kyoto rats].
Topics: Animals; Bicuculline; Brain; Chlorine; Ethanol; Female; Flunitrazepam; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Lew; Rats, Inbred WKY; Receptors, GABA-A; Substance-Related Disorders | 1995 |
Pharmacological properties of fetal rat hippocampal GABAA receptors.
Topics: Anesthetics; Animals; Cells, Cultured; Drug Synergism; Embryo, Mammalian; Fetus; gamma-Aminobutyric Acid; Hippocampus; Patch-Clamp Techniques; Pentobarbital; Pregnanediones; Rats; Receptors, GABA-A | 1995 |
An autoradiographic study comparing the interactions of 3 alpha-OH-5 alpha-pregnan-20-one, pregnenolone sulfate and pentobarbital with [3S]-TBPS binding sites and their modulation by GABA in different structures of the rat brain.
Topics: Animals; Anti-Anxiety Agents; Autoradiography; Brain; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Mesencephalon; Pentobarbital; Pregnanolone; Pregnenolone; Rats; Rats, Wistar; Receptors, GABA-A | 1995 |
Pharmacology of GABA receptor Cl- channels in rat retinal bipolar cells.
Topics: Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Chloride Channels; Flunitrazepam; gamma-Aminobutyric Acid; Ion Channels; Membrane Potentials; Membrane Proteins; Neurons; Pentobarbital; Photoreceptor Cells; Picrotoxin; Pregnanediones; Rats; Receptors, GABA-A; Sesterterpenes; Strychnine | 1993 |
Enhancement of gamma-aminobutyric acid-activated chloride channel currents by lanthanides in rat dorsal root ganglion neurons.
Topics: Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Chlordiazepoxide; Chloride Channels; Dose-Response Relationship, Drug; Drug Synergism; Electric Conductivity; gamma-Aminobutyric Acid; Ganglia, Spinal; Ion Channels; Membrane Potentials; Metals, Rare Earth; Neurons; Penicillins; Pentobarbital; Picrotoxin; Rats; Rats, Sprague-Dawley; Terbium; Zinc | 1993 |
Trichloroethanol potentiation of gamma-aminobutyric acid-activated chloride current in mouse hippocampal neurones.
Topics: Animals; Cells, Cultured; Chloride Channels; Drug Synergism; Ethanol; Ethylene Chlorohydrin; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Mice; Muscimol; Neurons; Patch-Clamp Techniques; Pentobarbital; Receptors, GABA-A; Up-Regulation | 1994 |
Novel properties of homomeric beta 1 gamma-aminobutyric acid type A receptors: actions of the anesthetics propofol and pentobarbital.
Topics: Animals; Bicuculline; Female; gamma-Aminobutyric Acid; Pentobarbital; Picrotoxin; Propofol; Receptors, GABA-A; Strychnine; Xenopus laevis | 1995 |
Enhancement of GABA-activated membrane currents in aged Fischer 344 rat basal forebrain neurons.
Topics: Action Potentials; Aging; Animals; Bicuculline; Drug Synergism; gamma-Aminobutyric Acid; Ion Channel Gating; Lanthanum; Midazolam; Pentobarbital; Rats; Rats, Inbred F344; Receptors, GABA-A; Septum Pellucidum; Tetrodotoxin; Zinc | 1995 |
GABA-activated chloride currents of postnatal mouse retinal ganglion cells are blocked by acetylcholine and acetylcarnitine: how specific are ion channels in immature neurons?
Topics: Acetylcarnitine; Acetylcholine; Action Potentials; Animals; Bicuculline; Chloride Channels; Clonazepam; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Mice; Mice, Inbred C57BL; Neurons; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Potassium Chloride; Pregnanolone; Quinoxalines; Retina; Retinal Ganglion Cells; Strychnine; Substrate Specificity; Tetrodotoxin; Zinc | 1994 |
The cell surface progesterone receptor which stimulates calcium influx in human sperm is unlike the A ring reduced steroid site on the GABAA receptor/chloride channel.
Topics: Acrosome; Binding Sites; Calcium; Chloride Channels; Chlorides; Diazepam; gamma-Aminobutyric Acid; Humans; Male; Pentobarbital; Picrotoxin; Progesterone; Receptors, GABA; Receptors, Progesterone; Spermatozoa | 1994 |
Cloning and functional expression of a Drosophila gamma-aminobutyric acid receptor.
Topics: Amino Acid Sequence; Animals; Base Sequence; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cloning, Molecular; Convulsants; DNA Primers; DNA, Complementary; Drosophila melanogaster; Female; Flunitrazepam; gamma-Aminobutyric Acid; Gene Expression; Macromolecular Substances; Molecular Sequence Data; Muscimol; Oocytes; Pentobarbital; Picrotoxin; Polymerase Chain Reaction; Receptors, GABA; Receptors, GABA-A; Transcription, Genetic; Xenopus laevis | 1994 |
Effects of propofol, pentobarbital and alphaxalone on t-[35S]butylbicyclophosphorothionate binding in rat cerebral cortex.
Topics: Anesthetics; Animals; Bicuculline; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chloride Channels; Diazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channel Gating; Male; Membranes; Pentobarbital; Pregnanediones; Propofol; Rats; Rats, Sprague-Dawley; Sulfur Radioisotopes | 1994 |
Calcium current block by (-)-pentobarbital, phenobarbital, and CHEB but not (+)-pentobarbital in acutely isolated hippocampal CA1 neurons: comparison with effects on GABA-activated Cl- current.
Topics: Animals; Barbiturates; Calcium Channel Blockers; Calcium Channels; Chloride Channels; Electric Conductivity; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; Hydrogen-Ion Concentration; Kinetics; Membrane Potentials; Membrane Proteins; Neurons; Pentobarbital; Phenobarbital | 1993 |
A novel GABA receptor on bipolar cell terminals in the tiger salamander retina.
Topics: Animals; Bicuculline; Chlorides; Crotonates; Electrophysiology; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Muscimol; Pentobarbital; Picrotoxin; Pyridazines; Receptors, GABA; Receptors, GABA-A; Retina; Retinal Ganglion Cells; Urodela | 1994 |
A novel allosteric modulatory site on the GABAA receptor beta subunit.
Topics: Allosteric Site; Animals; Anticonvulsants; Cells, Cultured; Chlorides; Drug Synergism; Electric Conductivity; Electrophysiology; Female; gamma-Aminobutyric Acid; Gene Expression; Humans; Pentobarbital; Pregnanolone; Rats; Receptors, GABA; Transfection; Triazoles; Xenopus | 1994 |
Dual action of the cyclodiene insecticide dieldrin on the gamma-aminobutyric acid receptor-chloride channel complex of rat dorsal root ganglion neurons.
Topics: Animals; Binding Sites; Chlordiazepoxide; Chloride Channels; Dieldrin; Drug Interactions; gamma-Aminobutyric Acid; Ganglia, Spinal; In Vitro Techniques; Kinetics; Membrane Potentials; Neurons, Afferent; Pentobarbital; Picrotoxin; Rats; Receptors, GABA-A | 1994 |
Interaction of ethanol and allosteric modulators with GABAA-activated currents in adult medial septum/diagonal band neurons.
Topics: Allosteric Regulation; Animals; Ethanol; Frontal Lobe; gamma-Aminobutyric Acid; Lanthanum; Male; Microinjections; Midazolam; Neurons; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A; Septum Pellucidum; Zinc | 1994 |
Structure, pharmacology and function of GABA-A receptors in cochlear outer hair cells.
Topics: Animals; Clorazepate Dipotassium; Dose-Response Relationship, Drug; Electrophysiology; gamma-Aminobutyric Acid; Guinea Pigs; Hair Cells, Auditory, Outer; In Vitro Techniques; Membrane Potentials; Pentobarbital; Picrotoxin; Receptors, GABA-A | 1993 |
Tolerance to the behavioral effects of chlordiazepoxide: pharmacological and biochemical selectivity.
Topics: Amphetamine; Animals; Behavior, Animal; Caffeine; Carbolines; Chlordiazepoxide; Chlorides; Chlorine; Dose-Response Relationship, Drug; Drug Tolerance; Flumazenil; gamma-Aminobutyric Acid; Male; Midazolam; Morphine; Pentobarbital; Radioisotopes; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sensitivity and Specificity; Stimulation, Chemical | 1993 |
Modulation of the developing rat sympathetic GABAA receptor by Zn++, benzodiazepines, barbiturates and ethanol.
Topics: Aging; Animals; Barbiturates; Benzodiazepines; Bicuculline; Diazepam; Ethanol; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Neurons; Pentobarbital; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sensitivity and Specificity; Superior Cervical Ganglion; Zinc | 1993 |
GABA and pentobarbital potentiation of chloride influx into microsacs is influenced by incubation time.
Topics: Animals; Cell Fractionation; Cerebral Cortex; Chlorides; Drug Synergism; gamma-Aminobutyric Acid; Kinetics; Male; Organelles; Pentobarbital; Rats; Rats, Wistar; Time Factors | 1993 |
The influence of the gamma 2L subunit on the modulation of responses to GABAA receptor activation.
Topics: Anesthetics; Animals; Fibroblasts; Flunitrazepam; gamma-Aminobutyric Acid; L Cells; Mice; Pentobarbital; Pregnanediones; Receptors, GABA-A; Recombinant Proteins; Transfection | 1993 |
Properties of GABA-mediated synaptic potentials induced by zinc in adult rat hippocampal pyramidal neurones.
Topics: Action Potentials; Animals; Bicuculline; Culture Techniques; Flurazepam; gamma-Aminobutyric Acid; Hippocampus; Male; Membrane Potentials; Pentobarbital; Picrotoxin; Rats; Synapses; Synaptic Transmission; Zinc | 1993 |
Characterization of the gamma-aminobutyric acidA receptor-channel complex composed of alpha 1 beta 2 and alpha 1 beta 3 subunits from rat brain.
Topics: Animals; Brain; Chlorides; CHO Cells; Cricetinae; Diazepam; gamma-Aminobutyric Acid; Membrane Potentials; Pentobarbital; Pregnanediones; Rats; Receptors, GABA-A; Transfection | 1993 |
Potentiation of gamma-aminobutyric acid type A receptor-mediated synaptic currents by pentobarbital and diazepam in immature hippocampal CA1 neurons.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Diazepam; Drug Synergism; Flumazenil; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Neurons; Pentobarbital; Rats; Rats, Wistar; Receptors, GABA-A; Synapses | 1993 |
Attenuation of anticonvulsant effects of diazepam after chronic treatment with bicuculline.
Topics: Animals; Anticonvulsants; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Male; Muscimol; Pentobarbital; Rats; Rats, Inbred F344; Rats, Inbred Lew; Receptors, GABA; Sleep | 1993 |
Novel GABA responses from rod-driven retinal horizontal cells.
Topics: Animals; Bicuculline; Chlorides; Crotonates; Diazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Muscimol; Pentobarbital; Perches; Photoreceptor Cells; Receptors, GABA; Retina | 1993 |
Effects of chronic pentobarbital treatment on the GABAA receptor complex in mammalian cortical neurons.
Topics: Animals; Benzodiazepines; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Cerebral Cortex; gamma-Aminobutyric Acid; Mice; Mice, Inbred C57BL; Neurons; Pentobarbital; Radioligand Assay; Receptors, GABA-A; Sulfur Radioisotopes; Tritium | 1995 |
Allosteric modulation of [3H]flunitrazepam binding to recombinant GABAA receptors.
Topics: Allosteric Regulation; Animals; Binding, Competitive; Cell Line; Cerebellum; Dose-Response Relationship, Drug; Etomidate; Flunitrazepam; gamma-Aminobutyric Acid; Humans; Kidney; Pentobarbital; Radioligand Assay; Rats; Receptors, GABA-A | 1995 |
Electrophysiological characterization of GABAA receptors in anterior pituitary cells of newborn rats.
Topics: Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Diazepam; Drug Tolerance; Electric Conductivity; Electrophysiology; Female; GABA Antagonists; gamma-Aminobutyric Acid; Kinetics; Membrane Potentials; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Pituitary Gland, Anterior; Rats; Receptors, GABA; Zinc | 1995 |
L-lysine is a barbiturate-like anticonvulsant and modulator of the benzodiazepine receptor.
Topics: Animals; Anions; Anticonvulsants; Barbiturates; Bicuculline; Brain Chemistry; Cattle; Central Nervous System Depressants; Diazepam; gamma-Aminobutyric Acid; Lysine; Male; Mice; Pentobarbital; Picrotoxin; Radioligand Assay; Receptors, GABA-A; Stimulation, Chemical | 1995 |
Biochemical evaluations of the effects of loreclezole and propofol on the GABAA receptor in rat brain.
Topics: Anesthetics; Animals; Anticonvulsants; Brain; Bridged Bicyclo Compounds, Heterocyclic; Diazepam; Flunitrazepam; GABA Modulators; gamma-Aminobutyric Acid; Hypnotics and Sedatives; In Vitro Techniques; Male; Muscimol; Pentobarbital; Pregnanediones; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sulfur Radioisotopes; Triazoles; Tritium | 1996 |
Cloning of cDNAs encoding the human gamma-aminobutyric acid type A receptor alpha 6 subunit and characterization of the pharmacology of alpha 6-containing receptors.
Topics: Amino Acid Sequence; Animals; Antisense Elements (Genetics); Autoradiography; Base Sequence; Cerebellar Cortex; Cloning, Molecular; DNA Primers; DNA, Complementary; Female; Flunitrazepam; gamma-Aminobutyric Acid; Humans; In Situ Hybridization; Kinetics; L Cells; Ligands; Macromolecular Substances; Membrane Potentials; Mice; Molecular Sequence Data; Oocytes; Pentobarbital; Polymerase Chain Reaction; Pregnanolone; Rats; Receptors, GABA-A; Recombinant Proteins; RNA, Messenger; Sequence Homology, Amino Acid; Transfection; Xenopus laevis | 1996 |
Homomeric beta 1 gamma-aminobutyric acid A receptor-ion channels: evaluation of pharmacological and physiological properties.
Topics: Animals; Binding Sites; Cattle; DNA, Complementary; Evaluation Studies as Topic; Female; GABA Modulators; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Ion Channels; Macromolecular Substances; Membrane Potentials; Mice; Oocytes; Pentobarbital; Receptors, GABA-A; Transfection; Xenopus laevis | 1996 |
Properties of putative cerebellar gamma-aminobutyric acid A receptor isoforms.
Topics: Animals; Carbolines; Cerebellum; Convulsants; Diazepam; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Ion Channels; Isomerism; Membrane Potentials; Mice; Pentobarbital; Picrotoxin; Rats; Receptors, GABA-A; Transfection | 1996 |
Effects of hypothermia, pentobarbital, and isoflurane on postdepolarization amino acid release during complete global cerebral ischemia.
Topics: Anesthetics, Inhalation; Animals; Aspartic Acid; Brain Ischemia; Calcium; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hypnotics and Sedatives; Hypothermia, Induced; Isoflurane; Male; Pentobarbital; Rats; Rats, Sprague-Dawley | 1996 |
Interaction of positive allosteric modulators with human and Drosophila recombinant GABA receptors expressed in Xenopus laevis oocytes.
Topics: Allosteric Regulation; Animals; Dose-Response Relationship, Drug; Drosophila; gamma-Aminobutyric Acid; Humans; Oocytes; Pentobarbital; Receptors, GABA; Recombination, Genetic; Xenopus laevis | 1996 |
Pentobarbital modulatory effect on GABA binding sites in developing chick optic lobe.
Topics: Animals; Bicuculline; Brain; Chick Embryo; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Pentobarbital; Picrotoxin; Sesterterpenes; Synaptic Membranes | 1995 |
Taurine allosterically inhibits binding of [35S]-t-butylbicyclophosphorothionate (TBPS) to rat brain synaptic membranes.
Topics: Allosteric Regulation; Animals; Bicuculline; Binding Sites; Brain Stem; Bridged Bicyclo Compounds, Heterocyclic; Clonazepam; Convulsants; gamma-Aminobutyric Acid; Male; Pentobarbital; Rats; Rats, Sprague-Dawley; Sulfur Radioisotopes; Synaptic Membranes; Taurine | 1995 |
Protective effects of GABAergic drugs and other anticonvulsants in lithium-pilocarpine-induced status epilepticus.
Topics: Animals; Anticonvulsants; Baclofen; Clonazepam; Diazepam; Dizocilpine Maleate; Ethanol; GABA Agents; gamma-Aminobutyric Acid; Lithium Chloride; Male; Neuroprotective Agents; Pentobarbital; Phenobarbital; Phenytoin; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus; Valproic Acid | 1996 |
Barbiturate interactions at the human GABAA receptor: dependence on receptor subunit combination.
Topics: Animals; DNA, Complementary; Electrophysiology; Female; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Humans; Oocytes; Patch-Clamp Techniques; Pentobarbital; Receptors, GABA-A; Xenopus laevis | 1996 |
The differential antagonism by bicuculline and SR95531 of pentobarbitone-induced currents in cultured hippocampal neurons.
Topics: Anesthetics, General; Anesthetics, Intravenous; Animals; Bicuculline; Binding Sites; Cells, Cultured; Chloride Channels; Chlorides; Etomidate; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Hippocampus; Models, Molecular; Neurons; Pentobarbital; Pyridazines; Rats; Receptors, GABA-A | 1996 |
Potentiation by sevoflurane of the gamma-aminobutyric acid-induced chloride current in acutely dissociated CA1 pyramidal neurones from rat hippocampus.
Topics: Animals; Chloride Channels; Diazepam; Drug Synergism; Ethers; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Ion Channel Gating; Methyl Ethers; Neurons; Pentobarbital; Pregnanolone; Rats; Rats, Wistar; Receptors, GABA-A; Sevoflurane | 1996 |
Direct activation of GABAA receptors by barbiturates in cultured rat hippocampal neurons.
Topics: Animals; Cells, Cultured; Chlorides; Dose-Response Relationship, Drug; Electrophysiology; Female; GABA Antagonists; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Kinetics; Neurons; Pentobarbital; Phenobarbital; Picrotoxin; Pregnancy; Prohibitins; Rats; Rats, Sprague-Dawley; Time Factors | 1996 |
Bicuculline and gabazine are allosteric inhibitors of channel opening of the GABAA receptor.
Topics: Allosteric Regulation; Allosteric Site; Amino Acid Sequence; Animals; Bicuculline; Binding Sites; Binding, Competitive; Cell Line; Coturnix; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Ion Channel Gating; Ion Transport; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Pentobarbital; Point Mutation; Pregnanediones; Pregnanolone; Protein Binding; Pyridazines; Receptors, GABA-A; Structure-Activity Relationship | 1997 |
Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit.
Topics: Amino Acid Sequence; Anesthetics, Intravenous; Animals; Bicuculline; Brain; Cell Line; Consensus Sequence; DNA, Complementary; Flumazenil; Flunitrazepam; GABA Agents; gamma-Aminobutyric Acid; Humans; Molecular Sequence Data; Muscimol; Pentobarbital; Picrotoxin; Pregnanolone; Propofol; Rats; Receptors, GABA-A; Recombinant Proteins; RNA, Messenger; Transfection | 1997 |
A structural determinant of desensitization and allosteric regulation by pentobarbitone of the GABAA receptor.
Topics: Allosteric Regulation; Amino Acid Sequence; Baculoviridae; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Pentobarbital; Receptors, GABA | 1997 |
Diazepam-insensitive GABAA receptors on postnatal spiral ganglion neurones in culture.
Topics: Animals; Animals, Newborn; Baclofen; Bicuculline; Carbolines; Cells, Cultured; Convulsants; Diazepam; Flunitrazepam; gamma-Aminobutyric Acid; Membrane Potentials; Neurons; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Spiral Ganglion; Zinc | 1997 |
Modulation by general anaesthetics of rat GABAA receptors comprised of alpha 1 beta 3 and beta 3 subunits expressed in human embryonic kidney 293 cells.
Topics: Anesthetics, General; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Transformed; gamma-Aminobutyric Acid; Humans; Pentobarbital; Pregnanolone; Propofol; Radioligand Assay; Rats; Receptors, GABA-A; Recombinant Proteins; Sulfur Radioisotopes | 1997 |
Modulation of GABAA receptor-mediated IPSCs by neuroactive steroids in a rat hypothalamo-hypophyseal coculture model.
Topics: Animals; Animals, Newborn; Cells, Cultured; Electrophysiology; Female; GABA Modulators; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Hypothalamo-Hypophyseal System; Membrane Potentials; Pentobarbital; Pregnancy; Pregnanes; Pregnanolone; Pregnenolone; Rats; Rats, Wistar; Receptors, GABA-A | 1997 |
Modulation of the GABAA response in rat ventromedial hypothalamic neurons by pregnanolone.
Topics: Animals; Chloride Channels; Chlorides; Diazepam; Drug Interactions; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Transport; Pentobarbital; Pregnanolone; Rats; Rats, Wistar; Receptors, GABA-A; Stereoisomerism; Structure-Activity Relationship; Ventromedial Hypothalamic Nucleus | 1997 |
Electrophysiological effects of various neuroactive steroids on the GABA(A) receptor in pituitary melanotrope cells.
Topics: Animals; Cells, Cultured; Dehydroepiandrosterone; Electrophysiology; GABA Modulators; gamma-Aminobutyric Acid; Neurotransmitter Agents; Patch-Clamp Techniques; Pentobarbital; Pituitary Gland; Pregnenolone; Rana ridibunda; Receptors, GABA-A; Steroids | 1997 |
Inhibitory effects of corymine, an alkaloidal component from the leaves of Hunteria zeylanica, on glycine receptors expressed in Xenopus oocytes.
Topics: Alkaloids; Animals; Bicuculline; Brain; Convulsants; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Midazolam; Oocytes; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Plant Leaves; Rats; Receptors, GABA-A; Receptors, Glycine; Trees; Xenopus | 1997 |
The interactions of hexachlorocyclohexane isomers with human gamma-aminobutyric acid(A) receptors expressed in Xenopus oocytes.
Topics: Animals; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Hexachlorocyclohexane; Humans; Insecticides; Pentobarbital; Picrotoxin; Receptors, GABA-A; Recombinant Proteins; Xenopus | 1997 |
Ionic mechanisms of spontaneous GABAergic events in rat hippocampal slices exposed to 4-aminopyridine.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Animals; Benzolamide; Bicarbonates; Carbonic Anhydrases; Enzyme Inhibitors; Ethoxzolamide; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Hippocampus; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Models, Neurological; Pentobarbital; Picrotoxin; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Reaction Time; Receptors, GABA-A; Receptors, Metabotropic Glutamate | 1997 |
The role of alpha1 and alpha6 subtype amino-terminal domains in allosteric regulation of gamma-aminobutyric acida receptors.
Topics: Allosteric Regulation; Animals; Cell Line; Diazepam; DNA, Complementary; Furosemide; gamma-Aminobutyric Acid; Lanthanum; Pentobarbital; Rats; Receptors, GABA-A; Zinc | 1997 |
PNU-107484A with alpha isoform-dependent functional changes in alpha(x)beta2gamma2 subtypes of rat recombinant GABA(A) receptors.
Topics: Allosteric Regulation; Animals; Blotting, Northern; Cell Line; Chloride Channels; GABA Agents; gamma-Aminobutyric Acid; Humans; Kidney; Patch-Clamp Techniques; Pentobarbital; Pyridines; Pyrimidines; Rats; Receptors, GABA-A; Recombinant Proteins; RNA, Messenger | 1997 |
GABA(A) receptor function in the cerebral cortex of alcohol-naive P and NP rats.
Topics: Animals; Cerebral Cortex; Chlorine; Choice Behavior; Drug Synergism; Ethanol; gamma-Aminobutyric Acid; Male; Pentobarbital; Phenobarbital; Radioisotopes; Rats; Receptors, GABA-A | 1998 |
GABAA receptor pharmacology and subtype mRNA expression in human neuronal NT2-N cells.
Topics: Anticonvulsants; Bicuculline; Carbolines; Convulsants; Diazepam; Diuretics; DNA Primers; Furosemide; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Lanthanum; Neurons; Patch-Clamp Techniques; Pentobarbital; Phenobarbital; Picrotoxin; Polymerase Chain Reaction; Pregnanediones; Pregnenolone; Pyridines; Receptors, GABA-A; RNA, Messenger; Teratocarcinoma; Triazoles; Tumor Cells, Cultured; Zinc; Zolpidem | 1998 |
Separate domains for desensitization of GABA rho 1 and beta 2 subunits expressed in Xenopus oocytes.
Topics: Amino Acid Sequence; Animals; Chloroform; Drug Synergism; Female; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Humans; Models, Biological; Molecular Sequence Data; Oocytes; Pentobarbital; Protein Structure, Tertiary; Rats; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Recombinant Fusion Proteins; RNA, Complementary; Xenopus | 1998 |
GABA-evoked depolarisations in the rat cortical wedge: involvement of GABAA receptors and HCO3- ions.
Topics: Animals; Bicarbonates; Bicuculline; Cerebral Cortex; Chlordiazepoxide; Electrophysiology; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; In Vitro Techniques; Ions; Pentobarbital; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 1998 |
Lack of tolerance to the anxiolytic effect of diazepam and pentobarbital following chronic administration in perinatally undernourished rats.
Topics: Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Anti-Anxiety Agents; Brain; Chlorides; Diazepam; Drug Synergism; Drug Tolerance; Female; gamma-Aminobutyric Acid; Maze Learning; Nutrition Disorders; Pentobarbital; Rats; Rats, Wistar; Time Factors | 1998 |
Ethanol selectively enhances the hyperpolarizing component of neocortical neuronal responses to locally applied GABA.
Topics: Animals; Central Nervous System Depressants; Electrophysiology; Ethanol; Flunitrazepam; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Male; Membrane Potentials; Neocortex; Neurons; Pentobarbital; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synapses | 1998 |
Functional characterization and visualization of a GABAA receptor-GFP chimera expressed in Xenopus oocytes.
Topics: Anesthetics; Animals; Bicuculline; Cell Membrane; Desoxycorticosterone; Dose-Response Relationship, Drug; Electrophysiology; Female; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Gene Expression; Genes, Reporter; Green Fluorescent Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Indicators and Reagents; Ion Channel Gating; Luminescent Proteins; Membrane Potentials; Microscopy, Confocal; Midazolam; Oocytes; Pentobarbital; Picrotoxin; Receptors, GABA-A; Recombinant Fusion Proteins; Xenopus laevis | 1998 |
Absence seizures decrease steroid modulation of t-[35S]butylbicyclophosphorothionate binding in thalamic relay nuclei.
Topics: Action Potentials; Animals; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Desoxycorticosterone; Epilepsy, Absence; gamma-Aminobutyric Acid; Hydroxybutyrates; Male; Pentobarbital; Pregnanediones; Rats; Rats, Sprague-Dawley; Sulfur Radioisotopes; Thalamic Nuclei | 1998 |
Bimodal action of furosemide on convulsant [3H]EBOB binding to cerebellar and cortical GABA(A) receptors.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cerebellum; Cerebral Cortex; Chlorides; Convulsants; Furosemide; GABA Modulators; gamma-Aminobutyric Acid; Kinetics; Niflumic Acid; Pentobarbital; Rats; Rats, Wistar; Receptors, GABA-A | 1998 |
Spontaneous and gamma-aminobutyric acid (GABA)-activated GABA(A) receptor channels formed by epsilon subunit-containing isoforms.
Topics: Animals; Cell Line; Dose-Response Relationship, Drug; Furosemide; gamma-Aminobutyric Acid; Lanthanum; Mice; Pentobarbital; Protein Isoforms; Rats; Receptors, GABA-A; Triazoles; Zinc | 1999 |
Complementary regulation of anaesthetic activation of human (alpha6beta3gamma2L) and Drosophila (RDL) GABA receptors by a single amino acid residue.
Topics: Amino Acids; Anesthetics, General; Anesthetics, Intravenous; Animals; Biotransformation; Cells, Cultured; Drosophila; Electrophysiology; GABA Modulators; gamma-Aminobutyric Acid; Humans; Membrane Potentials; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Pentobarbital; Propofol; Receptors, GABA; Xenopus laevis | 1999 |
Increased anxiety and altered responses to anxiolytics in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Crosses, Genetic; Diazepam; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Isoenzymes; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Knockout; Pentobarbital; Receptors, GABA-A; Reflex | 1999 |
A single hydrophobic residue confers barbiturate sensitivity to gamma-aminobutyric acid type C receptor.
Topics: Amino Acid Sequence; Amino Acid Substitution; Chloride Channels; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Membrane Proteins; Methionine; Molecular Sequence Data; Mutagenesis, Site-Directed; Pentobarbital; Receptors, GABA; Recombinant Proteins; Sequence Homology, Amino Acid; Thiopental; Tryptophan | 1999 |
The effects of a point mutation of the beta2 subunit of GABA(A) receptor on direct and modulatory actions of general anesthetics.
Topics: Amino Acid Substitution; Anesthetics, General; Animals; Chloride Channels; Dose-Response Relationship, Drug; Etomidate; GABA Modulators; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Membrane Potentials; Mice; Oocytes; Pentobarbital; Phenylalanine; Point Mutation; Propofol; Receptors, GABA-A; Tyrosine; Xenopus laevis | 1999 |
Enhancement of GABA-activated current by muscarine in rat dorsal root ganglion neurons.
Topics: Acetylcholine; Action Potentials; Animals; Atropine; Bicuculline; Carbachol; Carbolines; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Female; GABA Agonists; GABA Modulators; Gallamine Triethiodide; gamma-Aminobutyric Acid; Ganglia, Spinal; Ion Channel Gating; Ion Channels; Male; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Nerve Tissue Proteins; Nicotinic Antagonists; Patch-Clamp Techniques; Pentobarbital; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Muscarinic | 1999 |
Stimulation of chloride in-->out permeation across the Deiters' neuron membrane by pentobarbital on the cytoplasmic side: additional evidence of GABA(A) receptors acting as chloride extrusion pumps.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Cell Membrane; Cell Membrane Permeability; Chlorides; Cytoplasm; GABA Modulators; gamma-Aminobutyric Acid; Male; Neurons; Pentobarbital; Rabbits; Receptors, GABA; Vestibular Nucleus, Lateral | 1999 |
GABA(A) receptors mediate inhibition of T cell responses.
Topics: Amidines; Animals; Autocrine Communication; Bicuculline; CD3 Complex; Cell Division; Enzyme Inhibitors; Female; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Hypersensitivity, Delayed; Immunosuppression Therapy; Interleukin-2; Lymphocyte Activation; Male; Mice; Mice, Inbred NOD; Muscimol; Pentobarbital; Picrotoxin; Receptors, GABA-A; Receptors, GABA-B; Signal Transduction; T-Lymphocytes; Vigabatrin | 1999 |
Studies on the neuroprotective effect of pentobarbitone on MDMA-induced neurodegeneration.
Topics: Animals; Body Temperature; Brain; gamma-Aminobutyric Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neuroprotective Agents; Paroxetine; Pentobarbital; Rats | 1999 |
Neuropsychopharmacological profile of the methanolic fraction of Bryophyllum pinnatum leaf extract.
Topics: Analgesia; Animals; Anticonvulsants; Behavior, Animal; Brain Chemistry; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Male; Methanol; Mice; Muscle Relaxation; Pentobarbital; Plant Extracts; Plant Leaves; Rats; Sleep | 1999 |
Dual effects of pentobarbital on rat sacral dorsal commissural neurons in vitro.
Topics: Adjuvants, Anesthesia; Animals; Animals, Newborn; Chloride Channels; GABA Modulators; gamma-Aminobutyric Acid; In Vitro Techniques; Neurons; Patch-Clamp Techniques; Pentobarbital; Rats; Rats, Sprague-Dawley; Spinal Cord | 1998 |
The interaction of general anaesthetics and neurosteroids with GABA(A) and glycine receptors.
Topics: Anesthetics; Animals; Drug Interactions; Electric Conductivity; Etomidate; Female; gamma-Aminobutyric Acid; Glycine; Mutagenesis, Site-Directed; Oocytes; Pentobarbital; Pregnanolone; Propofol; Receptors, GABA-A; Receptors, Glycine; Recombinant Proteins; Structure-Activity Relationship; Xenopus laevis | 1999 |
GABA-Induced Cl- current in cultured embryonic human dorsal root ganglion neurons.
Topics: Adult; Baclofen; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Chloride Channels; Convulsants; Crotonates; Embryo, Mammalian; gamma-Aminobutyric Acid; Ganglia, Spinal; Glycine; Humans; Membrane Potentials; Neurons; Patch-Clamp Techniques; Pentobarbital; Potassium Channels; Pregnanediones; Receptors, GABA-A; Taurine | 1999 |
A single amino acid confers barbiturate sensitivity upon the GABA rho 1 receptor.
Topics: Anesthetics, General; Animals; Binding Sites; Central Nervous System Depressants; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Hexachlorocyclohexane; Humans; Hypnotics and Sedatives; Isoleucine; Oocytes; Pentobarbital; Receptors, GABA-A; Serine; Structure-Activity Relationship; Xenopus laevis | 1999 |
Stereoselective interaction of thiopentone enantiomers with the GABA(A) receptor.
Topics: Animals; Binding Sites; Chelating Agents; Dose-Response Relationship, Drug; Drug Synergism; Egtazic Acid; Electric Conductivity; Female; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Humans; Hydrogen-Ion Concentration; Kinetics; Oocytes; Patch-Clamp Techniques; Pentobarbital; Receptors, GABA-A; Stereoisomerism; Substrate Specificity; Thiopental; Xenopus laevis | 1999 |
Synaptic membrane freezing affects modulatory sites in avian central nervous system GABA(A) receptor.
Topics: Animals; Binding Sites; Chickens; Drug Synergism; Freezing; GABA Modulators; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Pentobarbital; Picrotoxin; Pregnanolone; Receptors, GABA-A; Sesterterpenes; Synaptic Membranes; Tectum Mesencephali; Tritium | 1999 |
Mutant human alpha(1)beta(1)(T262Q) GABA(A) receptors are directly activated but not modulated by pentobarbital.
Topics: Amino Acid Substitution; Animals; Cell Line; Dose-Response Relationship, Drug; GABA Modulators; gamma-Aminobutyric Acid; Humans; Kinetics; Membrane Potentials; Mutation; Patch-Clamp Techniques; Pentobarbital; Receptors, GABA-A; Recombinant Fusion Proteins | 1999 |
Activation of rat locus coeruleus neuron GABA(A) receptors by propofol and its potentiation by pentobarbital or alphaxalone.
Topics: Anesthetics; Anesthetics, Intravenous; Animals; Baclofen; Barium Compounds; Bicuculline; Chlorides; Diazepam; Drug Synergism; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Ionophores; Locus Coeruleus; Male; Neurons; Pentobarbital; Picrotoxin; Pregnanediones; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Zinc Compounds | 1999 |
Identification of residues within GABA(A) receptor alpha subunits that mediate specific assembly with receptor beta subunits.
Topics: Amino Acid Sequence; Amino Acid Substitution; Cell Line; Cell Membrane; Endoplasmic Reticulum; gamma-Aminobutyric Acid; Gene Expression Regulation; Humans; Kidney; Macromolecular Substances; Mutagenesis, Site-Directed; Pentobarbital; Protein Isoforms; Receptors, GABA-A; Recombinant Fusion Proteins; Transfection; Tumor Cells, Cultured | 2000 |
A single glycine residue at the entrance to the first membrane-spanning domain of the gamma-aminobutyric acid type A receptor beta(2) subunit affects allosteric sensitivity to GABA and anesthetics.
Topics: Allosteric Regulation; Amino Acid Sequence; Anesthetics; Animals; Cells, Cultured; Chloride Channels; Electrophysiology; Etomidate; GABA Modulators; gamma-Aminobutyric Acid; Glycine; Ligands; Molecular Sequence Data; Mutagenesis, Site-Directed; Pentobarbital; Pregnanediones; Propofol; Protein Conformation; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Sequence Homology, Amino Acid; Spodoptera | 2000 |
Effects of standard anticonvulsant drugs on different patterns of epileptiform discharges induced by 4-aminopyridine in combined entorhinal cortex-hippocampal slices.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Carbamazepine; Entorhinal Cortex; Epilepsies, Partial; Female; gamma-Aminobutyric Acid; Hippocampus; Hypnotics and Sedatives; Male; Pentobarbital; Phenobarbital; Phenytoin; Prohibitins; Rats; Rats, Wistar; Valproic Acid | 2000 |
GABA(A) receptors on calbindin-immunoreactive myenteric neurons of guinea pig intestine.
Topics: Animals; Calbindins; Cells, Cultured; Diazepam; Dose-Response Relationship, Drug; GABA Agonists; GABA Modulators; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Guinea Pigs; Immunohistochemistry; Intestine, Small; Membrane Potentials; Muscimol; Myenteric Plexus; Neurons; Pentobarbital; Receptors, GABA-A; S100 Calcium Binding Protein G | 2000 |
Structural domains of the human GABAA receptor 3 subunit involved in the actions of pentobarbital.
Topics: Animals; Binding Sites; Cells, Cultured; Cloning, Molecular; Dose-Response Relationship, Drug; Fibroblasts; GABA Modulators; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Membrane Potentials; Models, Chemical; Patch-Clamp Techniques; Pentobarbital; Protein Structure, Tertiary; Quail; Rats; Receptors, GABA-A; Recombinant Fusion Proteins; Stimulation, Chemical; Structure-Activity Relationship | 2000 |
Heterogeneity of GABA(A) receptor-mediated responses in the human IMR-32 neuroblastoma cell line.
Topics: Anticonvulsants; Bicuculline; Diazepam; Dose-Response Relationship, Drug; GABA Modulators; gamma-Aminobutyric Acid; Humans; Neuroblastoma; Patch-Clamp Techniques; Pentobarbital; Pregnanolone; Protein Isoforms; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Triazoles; Tumor Cells, Cultured; Zinc | 2000 |
On the regulation of ischaemia-induced glutamate efflux from rat cortex by GABA; in vitro studies with GABA, clomethiazole and pentobarbitone.
Topics: Animals; Brain Ischemia; Cerebral Cortex; Chlormethiazole; Female; GABA Modulators; gamma-Aminobutyric Acid; Glutamic Acid; Pentobarbital; Rats; Rats, Wistar; Receptors, GABA-A | 2000 |
Anticonvulsive activity of Albizzia lebbeck, Hibiscus rosa sinesis and Butea monosperma in experimental animals.
Topics: Amphetamine; Animals; Anticonvulsants; Behavior, Animal; Brain Chemistry; Central Nervous System Stimulants; Convulsants; Electroshock; Epilepsy; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Lithium; Male; Mice; Muscarinic Agonists; Pentobarbital; Pentylenetetrazole; Pilocarpine; Plant Extracts; Plant Leaves; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Serotonin; Sleep | 2000 |
Modulation of gamma-aminobutyric acid responses in the rat optic nerve.
Topics: Animals; Chlordiazepoxide; Dose-Response Relationship, Drug; Drug Synergism; Electrophysiology; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Optic Nerve; Pentobarbital; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2000 |
Pentobarbital modulates gamma-aminobutyric acid-activated single-channel conductance in rat cultured hippocampal neurons.
Topics: Animals; Cells, Cultured; Diazepam; Drug Interactions; Electric Conductivity; Electrophysiology; GABA Modulators; gamma-Aminobutyric Acid; Hippocampus; Ion Channels; Kinetics; Neurons; Pentobarbital; Rats; Receptors, GABA-A | 2000 |
Inhibition of GABA(A) receptor (GABAR) currents by arachidonic acid in HEK 293 cells stably transfected with alpha1beta2gamma2 GABAR subunits.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Anticonvulsants; Arachidonic Acid; Binding, Competitive; Cells, Cultured; Cyclooxygenase Inhibitors; Diazepam; Dose-Response Relationship, Drug; Fatty Acids; Fatty Acids, Monounsaturated; GABA Antagonists; GABA Modulators; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Indomethacin; Kidney; Linoleic Acid; Masoprocol; Membrane Potentials; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Receptors, GABA-A; Recombinant Proteins; Transfection; Triazoles | 2000 |
Two conserved arginines in the extracellular N-terminal domain of the GABA(A) receptor alpha(5) subunit are crucial for receptor function.
Topics: Amino Acid Substitution; Animals; Arginine; Chlorides; CHO Cells; Cricetinae; Diazepam; GABA Modulators; gamma-Aminobutyric Acid; Gene Expression; Humans; Ion Channel Gating; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Pentobarbital; Pregnanolone; Protein Structure, Tertiary; Receptors, GABA-A; Sequence Alignment; Steroids; Structure-Activity Relationship; Transfection | 2000 |
GABAC receptors are localized with microtubule-associated protein 1B in mammalian cone photoreceptors.
Topics: Animals; Cell Separation; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA Modulators; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Immunohistochemistry; In Vitro Techniques; Membrane Potentials; Mice; Mice, Inbred C3H; Microtubule-Associated Proteins; Patch-Clamp Techniques; Pentobarbital; Phosphinic Acids; Pyridazines; Pyridines; Receptors, GABA; Retina; Retinal Cone Photoreceptor Cells; Retinal Rod Photoreceptor Cells | 2000 |
Bicuculline, pentobarbital and diazepam modulate spontaneous GABA(A) channels in rat hippocampal neurons.
Topics: Animals; Bicuculline; Cells, Cultured; Diazepam; GABA Modulators; gamma-Aminobutyric Acid; Hippocampus; Ion Channels; Pentobarbital; Rats; Receptors, GABA-A | 2000 |
Allosteric modulation in spontaneously active mutant gamma-aminobutyric acid(A) receptors [corrected].
Topics: Allosteric Regulation; Amino Acid Substitution; Animals; Bicuculline; Cells, Cultured; Female; Flunitrazepam; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Mutagenesis, Site-Directed; Oocytes; Pentobarbital; Picrotoxin; Protein Structure, Tertiary; Receptors, GABA-A; Steroids; Xenopus laevis | 2000 |
Acute hypoxic hypoxia transiently reduces GABA(A) binding site number in developing chick optic lobe.
Topics: Acute Disease; Allosteric Regulation; Animals; Binding Sites; Chick Embryo; GABA Modulators; gamma-Aminobutyric Acid; Hypoxia; Optic Lobe, Nonmammalian; Pentobarbital; Pregnanolone; Receptors, GABA-A; Time Factors | 2000 |
Developmental profile of excitatory GABA(A) responses in cultured rat cerebellar granule cells.
Topics: Allosteric Regulation; Animals; Bicuculline; Biological Transport; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Differentiation; Cells, Cultured; Cerebellum; Chlorides; Cytosol; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Mitochondria; Nifedipine; Pentobarbital; Rats; Rats, Wistar; Receptors, GABA-A; Steroids | 2001 |
Pregnenolone sulfate block of GABA(A) receptors: mechanism and involvement of a residue in the M2 region of the alpha subunit.
Topics: Binding Sites; Cell Line; Estranes; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Kidney; Ligands; Membrane Potentials; Mutagenesis; Nitriles; Patch-Clamp Techniques; Pentobarbital; Piperidines; Pregnenolone; Receptors, GABA-A; Transfection | 2001 |
Functional pharmacology of GABA(A) receptors containing the chicken brain gamma 4 subunit.
Topics: Animals; Bicuculline; Brain Chemistry; Chickens; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Humans; Oocytes; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Protein Subunits; Receptors, GABA-A; Recombinant Proteins; Xenopus laevis; Zinc | 2001 |
Neuropeptide Y alters sedation through a hypothalamic Y1-mediated mechanism.
Topics: Anesthetics; Animals; Drug Interactions; Ethanol; Excitatory Amino Acid Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Gene Expression; Hypnotics and Sedatives; Hypothalamus, Posterior; Ketamine; Mice; Mice, Knockout; Neurons; Neuropeptide Y; Pentobarbital; Receptors, Neuropeptide Y; RNA, Messenger; Sleep; Wakefulness | 2001 |
alpha4beta3delta GABA(A) receptors characterized by fluorescence resonance energy transfer-derived measurements of membrane potential.
Topics: Animals; Benzodiazepines; Cell Line; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Humans; Membrane Potentials; Mice; Models, Biological; Muscimol; Pentobarbital; Pregnanediones; Pregnanolone; Protein Binding; Protein Conformation; Receptors, GABA-A; Spectrometry, Fluorescence; Time Factors; Transfection | 2001 |
Effect of alkylpyrazine derivatives on the duration of pentobarbital-induced sleep, picrotoxicin-induced convulsion and gamma-aminobutyric acid (GABA) levels in the mouse brain.
Topics: Aminooxyacetic Acid; Animals; Anticonvulsants; Bicuculline; Brain Chemistry; Convulsants; Diazepam; GABA Agents; GABA Antagonists; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Injections, Intraventricular; Male; Mice; Pentobarbital; Picrotoxin; Pyrazines; Seizures; Sleep; Time Factors; Valproic Acid | 2001 |
Pentobarbital-induced place preference in rats is blocked by GABA, dopamine, and opioid antagonists.
Topics: Animals; Cardiotonic Agents; Conditioning, Psychological; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Male; Narcotic Antagonists; Pentobarbital; Rats; Rats, Long-Evans | 2001 |
Homeostatic plasticity induced by chronic block of AMPA/kainate receptors modulates the generation of rhythmic bursting in rat spinal cord organotypic cultures.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Chloride Channels; Electrophysiology; Excitatory Amino Acid Antagonists; Female; GABA Modulators; gamma-Aminobutyric Acid; Glycine Agents; Homeostasis; Immunohistochemistry; Neuronal Plasticity; Organ Culture Techniques; Patch-Clamp Techniques; Pentobarbital; Potassium; Pregnancy; Rats; Receptors, AMPA; Receptors, GABA-A; Receptors, Kainic Acid; Spinal Cord; Strychnine | 2001 |
GABA(A) receptor epsilon-subunit may confer benzodiazepine insensitivity to the caudal aspect of the nucleus tractus solitarii of the rat.
Topics: Animals; Anti-Anxiety Agents; Baroreflex; Benzodiazepines; Carbolines; Chlordiazepoxide; Electrophysiology; Excitatory Postsynaptic Potentials; Female; GABA Modulators; gamma-Aminobutyric Acid; Immunohistochemistry; In Vitro Techniques; Iontophoresis; Male; Midazolam; Pentobarbital; Rats; Rats, Wistar; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Solitary Nucleus | 2001 |
Influence of membrane cholesterol on modulation of the GABA(A) receptor by neuroactive steroids and other potentiators.
Topics: Animals; Cell Membrane; Cholesterol; Dose-Response Relationship, Drug; Drug Synergism; Flunitrazepam; gamma-Aminobutyric Acid; Hippocampus; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Pentobarbital; Pregnanolone; Pregnenolone; Propofol; Rats; Rats, Wistar; Receptors, GABA-A | 2001 |
Modulation of GABA(A) receptor channel gating by pentobarbital.
Topics: beta-Alanine; Cell Line; Dose-Response Relationship, Drug; Drug Synergism; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Ion Channels; Osmolar Concentration; Pentobarbital; Piperidines; Protein Isoforms; Receptors, GABA-A; Recombinant Proteins | 2001 |
Fibroblast growth factor 2 is necessary for the growth of glutamate projection neurons in the anterior neocortex.
Topics: Animals; Antigens, Differentiation; Cell Count; Cell Size; Cerebral Cortex; Fibroblast Growth Factor 2; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Interneurons; Mice; Mice, Knockout; Neocortex; Neurons; Pentobarbital; Pyramidal Cells; Reflex; Stem Cells | 2002 |
Point mutation in the first transmembrane region of the beta 2 subunit of the gamma--aminobutyric acid type A receptor alters desensitization kinetics of gamma--aminobutyric acid- and anesthetic-induced channel gating.
Topics: Amino Acid Sequence; Anesthetics; Animals; Cells, Cultured; Electrophysiology; gamma-Aminobutyric Acid; Ion Channel Gating; Kinetics; Molecular Sequence Data; Pentobarbital; Point Mutation; Propofol; Rats; Receptors, GABA-A; Sequence Alignment; Spodoptera | 2002 |
Amiloride inhibition of gamma-aminobutyric acid(A) receptors depends upon the alpha subunit subtype.
Topics: Amiloride; Animals; Cells, Cultured; Diuretics; Fibroblasts; Furosemide; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Mice; Pentobarbital; Protein Subunits; Rats; Receptors, GABA-A; Recombinant Proteins; Transfection | 2002 |
Anxiolytic and anticonvulsive activity of Sesbania grandiflora leaves in experimental animals.
Topics: Amphetamine; Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Brain Chemistry; Electroshock; Fabaceae; gamma-Aminobutyric Acid; India; Locomotion; Male; Medicine, Ayurvedic; Mice; Pentobarbital; Pentylenetetrazole; Phytotherapy; Plant Extracts; Plant Leaves; Rats; Rats, Sprague-Dawley; Seizures; Serotonin; Sleep | 2002 |
Pentobarbital enhances GABAergic neurotransmission to cardiac parasympathetic neurons, which is prevented by expression of GABA(A) epsilon subunit.
Topics: Adenoviridae; Animals; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Genetic Vectors; Heart; Heart Rate; Hypnotics and Sedatives; Parasympathetic Nervous System; Patch-Clamp Techniques; Pentobarbital; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synaptic Transmission; Transfection | 2002 |
1-Methyl-4-phenylpridinium (MPP+)-induced functional run-down of GABA(A) receptor-mediated currents in acutely dissociated dopaminergic neurons.
Topics: 1-Methyl-4-phenylpyridinium; Action Potentials; Adenosine Triphosphate; Animals; Cell Separation; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; GABA Antagonists; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; In Vitro Techniques; Membrane Glycoproteins; Membrane Transport Modulators; Membrane Transport Proteins; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Pentobarbital; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Substantia Nigra | 2002 |
Overexpression of the GABA(A) receptor epsilon subunit results in insensitivity to anaesthetics.
Topics: Anesthetics; Anesthetics, Intravenous; Animals; Blotting, Western; Cell Line; Cloning, Molecular; DNA, Complementary; Etomidate; Female; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Humans; Oocytes; Pentobarbital; Picrotoxin; Protein Engineering; Receptors, GABA-A; Steroids; Transfection; Xenopus laevis | 2002 |
Relative picrotoxin insensitivity distinguishes ionotropic GABA receptor-mediated IPSCs in hippocampal interneurons.
Topics: Animals; Bicuculline; Electrophysiology; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Interneurons; Iontophoresis; Membrane Potentials; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Pyramidal Cells; Pyridines; Receptors, GABA; Receptors, GABA-A; Zolpidem | 2002 |
Interaction of pentobarbital with gabaergic drugs acting on the Cl(-)-ATPase activity of the plasma membranes from bream brain (Abramis brama L.).
Topics: Adenosine Triphosphatases; Animals; Anion Transport Proteins; Baclofen; Bicuculline; Brain; Cell Membrane; Chlorides; Dose-Response Relationship, Drug; Drug Interactions; GABA Agents; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Male; Pentobarbital; Picrotoxin; Receptors, GABA-A; Sea Bream | 2002 |
The GABAA receptor alpha 1 subunit Pro174-Asp191 segment is involved in GABA binding and channel gating.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; gamma-Aminobutyric Acid; Ion Channel Gating; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Pentobarbital; Peptide Fragments; Protein Conformation; Protein Subunits; Rats; Receptors, GABA-A; Sequence Alignment; Sequence Homology, Amino Acid | 2003 |
Synchronization of kainate-induced epileptic activity via GABAergic inhibition in the superfused rat hippocampus in vivo.
Topics: Action Potentials; Animals; Diffusion Chambers, Culture; Disease Models, Animal; Electroencephalography; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; GABA Modulators; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Interneurons; Kainic Acid; Male; Neural Inhibition; Patch-Clamp Techniques; Pentobarbital; Perfusion; Periodicity; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2003 |
Conductance of GABAA channels activated by pentobarbitone in hippocampal neurons from newborn rats.
Topics: Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Diazepam; Electric Conductivity; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Hippocampus; Ion Channel Gating; Neurons; Patch-Clamp Techniques; Pentobarbital; Rats; Receptors, GABA-A | 2003 |
Allopregnanolone-stimulated GABA-mediated chloride ion flux is inhibited by 3beta-hydroxy-5alpha-pregnan-20-one (isoallopregnanolone).
Topics: Animals; Cerebral Cortex; Chlorides; Flunitrazepam; GABA Modulators; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Osmolar Concentration; Pentobarbital; Pregnanolone; Rats; Rats, Wistar | 2003 |
Cardiovascular responses to microinjections of GABA or anesthetics into the rostral ventrolateral medulla of conscious and anesthetized rats.
Topics: Anesthetics, Intravenous; Anesthetics, Local; Animals; Blood Pressure; Conscious Sedation; GABA Modulators; gamma-Aminobutyric Acid; Heart Rate; Lidocaine; Male; Medulla Oblongata; Microinjections; Pentobarbital; Rats; Rats, Wistar; Urethane | 2003 |
Reinforcing versus anticonvulsant drugs: effects on intracranial self-stimulation rate-frequency M50 indices.
Topics: Acetates; Amines; Amphetamine; Animals; Anticonvulsants; Central Nervous System Stimulants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Male; Medial Forebrain Bundle; Pentobarbital; Rats; Rats, Long-Evans; Reinforcement, Psychology; Self Stimulation | 2003 |
Effect of anesthetics on brain gamma-aminobutyric and glutamic acid levels.
Topics: Amino Acids; Anesthetics; Brain; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hypoxia; Mydriatics; Pentobarbital | 1963 |
A NEUROPHARMACOLOGICAL STUDY OF GAMMA-AMINOBUTYRIC ACID (GABA).
Topics: Aminobutyrates; Anesthesia; Anesthesia, Intravenous; Behavior, Animal; Brain Chemistry; Cats; Chlorpromazine; Electroencephalography; Electroshock; gamma-Aminobutyric Acid; Hydroxylamines; Metabolism; Neuropharmacology; Pentobarbital; Pentylenetetrazole; Pharmacology; Phenytoin; Research; Reserpine; Seizures; Strychnine; Toxicology | 1964 |
PHARMACOLOGICAL STUDIES OF THE OPTIC SYSTEM OF THE CHICK: EFFECT OF GAMMA-AMINOBUTYRIC ACID AND PENTOBARBITAL.
Topics: Aminobutyrates; Animals; Chickens; Electroretinography; gamma-Aminobutyric Acid; Mesencephalon; Optic Nerve; Pentobarbital; Pharmacology; Poultry; Research; Retina | 1964 |
Effects of some drugs on the gamma-aminobutyric acid transaminase and the succinic semialdehyde dehydrogenase of rat brain.
Topics: Animals; Anticonvulsants; Brain; gamma-Aminobutyric Acid; Hydantoins; Neurochemistry; Oxidoreductases; Pentobarbital; Rats; Succinate-Semialdehyde Dehydrogenase; Transaminases | 1961 |
Activity of chlormethiazole at human recombinant GABA(A) and NMDA receptors.
Topics: Animals; Chlormethiazole; DNA, Recombinant; Dose-Response Relationship, Drug; GABA Modulators; gamma-Aminobutyric Acid; Humans; Membrane Potentials; Oocytes; Pentobarbital; Propofol; Protein Subunits; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Xenopus laevis | 2003 |
Synthesis and biological evaluation of GABA derivatives able to cross the blood-brain barrier in rats.
Topics: Animals; Atropine; Binding, Competitive; Biotransformation; Blood-Brain Barrier; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Hydrolysis; Hypnotics and Sedatives; Injections, Intraperitoneal; Injections, Intravenous; Injections, Intraventricular; Magnetic Resonance Spectroscopy; Muscarinic Antagonists; Oxidation-Reduction; Pentobarbital; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Sleep | 2003 |
Pentobarbital modulates intrinsic and GABA-receptor conductances in thalamocortical inhibition.
Topics: Action Potentials; Animals; Cerebral Cortex; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Neural Inhibition; Neural Pathways; Patch-Clamp Techniques; Pentobarbital; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, GABA; Synaptic Transmission; Tetrodotoxin; Thalamus | 2003 |
Effects of pentobarbital on GABA-activated currents in acutely-isolated rat dentate gyrus granule neurons.
Topics: Animals; Cells, Cultured; Dentate Gyrus; Dose-Response Relationship, Drug; GABA Modulators; gamma-Aminobutyric Acid; Membrane Potentials; Neurons; Patch-Clamp Techniques; Pentobarbital; Rats; Rats, Wistar; Receptors, GABA-A | 2003 |
Potential pleiotropic effects of Mpdz on vulnerability to seizures.
Topics: Amino Acid Motifs; Animals; Carrier Proteins; Chromosome Mapping; Convulsants; Ethanol; Female; gamma-Aminobutyric Acid; Genetic Predisposition to Disease; Glutamic Acid; Male; Membrane Proteins; Mice; Mice, Inbred Strains; Pentobarbital; Phenotype; Quantitative Trait, Heritable; Seizures; Species Specificity; Substance Withdrawal Syndrome | 2004 |
Activation of GABA(A) receptors containing the alpha4 subunit by GABA and pentobarbital.
Topics: Cell Line; Cloning, Molecular; GABA Modulators; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Kidney; Membrane Potentials; Pentobarbital; Receptors, GABA-A | 2004 |
Expression of functional receptors by the human gamma-aminobutyric acid A gamma 2 subunit.
Topics: Amino Acids; Animals; Female; gamma-Aminobutyric Acid; Humans; Membrane Potentials; Oocytes; Pentobarbital; Plasmids; Receptors, GABA-A; Transcription, Genetic; Xenopus | 2004 |
Molecular basis for modulation of recombinant alpha1beta2gamma2 GABAA receptors by protons.
Topics: Bicuculline; Binding Sites; Cell Line; Diethyl Pyrocarbonate; Electrophysiology; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Humans; Hydrogen-Ion Concentration; Ion Channel Gating; Mutation; Patch-Clamp Techniques; Pentobarbital; Protons; Receptors, GABA-A; Recombinant Proteins; Zinc | 2004 |
Abnormal benzodiazepine and zinc modulation of GABAA receptors in an acquired absence epilepsy model.
Topics: Androstenes; Animals; Anticonvulsants; Benzodiazepines; Diazepam; Disease Models, Animal; Enzyme Inhibitors; Epilepsy, Absence; GABA Modulators; gamma-Aminobutyric Acid; Membrane Potentials; Patch-Clamp Techniques; Pentobarbital; Rats; Rats, Long-Evans; Receptors, GABA-A; Thalamic Nuclei; Zinc | 2004 |
The role of gamma-aminobutyric acid and glutamate for hypoxic ventilatory response in anesthetized rabbits.
Topics: Adjuvants, Anesthesia; Anesthesia; Animals; Aorta; Carotid Arteries; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Glutamic Acid; Hypoxia; Oxygen; Pentobarbital; Phrenic Nerve; Rabbits; Receptors, N-Methyl-D-Aspartate; Respiration | 2004 |
Pentobarbital differentially modulates alpha1beta3delta and alpha1beta3gamma2L GABAA receptor currents.
Topics: Cells, Cultured; Electrophysiology; GABA Modulators; gamma-Aminobutyric Acid; Humans; Pentobarbital; Protein Subunits; Receptors, GABA-A; Transfection | 2004 |
Pharmacological and anatomical evidence for an interaction between mGluR5- and GABA(A) alpha1-containing receptors in the discriminative stimulus effects of ethanol.
Topics: Alcoholism; Animals; Diazepam; Discrimination, Psychological; Disease Models, Animal; Drug Interactions; Ethanol; Excitatory Amino Acid Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Glutamic Acid; Immunohistochemistry; Male; Neurons; Pentobarbital; Pyridines; Rats; Rats, Long-Evans; Receptor, Metabotropic Glutamate 5; Receptors, GABA-A; Receptors, Metabotropic Glutamate; Synaptic Transmission; Telencephalon | 2005 |
Combined discriminative stimulus effects of midazolam with other positive GABAA modulators and GABAA receptor agonists in rhesus monkeys.
Topics: Animals; Behavior, Animal; Conditioning, Operant; Discrimination Learning; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Ethanol; GABA Modulators; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Injections, Subcutaneous; Isoxazoles; Macaca mulatta; Male; Midazolam; Pentobarbital; Pregnanolone; Receptors, GABA-A; Time Factors; Triazolam; Women | 2005 |
The contribution of GABA to glutamate/glutamine cycling and energy metabolism in the rat cortex in vivo.
Topics: Acetates; Amino Acids; Anesthetics, Inhalation; Animals; Biological Transport; Blood Glucose; Cerebral Cortex; Energy Metabolism; GABA Modulators; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Halothane; Magnetic Resonance Spectroscopy; Male; Neuroglia; Neurons; Oxidation-Reduction; Pentobarbital; Rats; Rats, Sprague-Dawley | 2005 |
Ethyl 2-(4-bromophenyl)-1-(2,4-dichlorophenyl)-1H-4-imidazolecarboxylate is a novel positive modulator of GABAA receptors.
Topics: Animals; Binding, Competitive; Cell Membrane; Cerebral Cortex; Diazepam; Dose-Response Relationship, Drug; Etomidate; Female; Flunitrazepam; GABA Modulators; gamma-Aminobutyric Acid; Glycine; Humans; Hydrocarbons, Halogenated; Imidazoles; Male; Membrane Potentials; Oocytes; Pentobarbital; Pregnanediones; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Glycine; Receptors, Serotonin, 5-HT3; Serotonin; Tritium; Xenopus laevis | 2005 |
Stiripentol, a putative antiepileptic drug, enhances the duration of opening of GABA-A receptor channels.
Topics: Animals; Animals, Newborn; Anticonvulsants; Chloride Channels; Dioxolanes; Disease Models, Animal; Drug Interactions; Epilepsy; Excitatory Postsynaptic Potentials; GABA Plasma Membrane Transport Proteins; GABA Uptake Inhibitors; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Neural Inhibition; Nipecotic Acids; Oximes; Patch-Clamp Techniques; Pentobarbital; Pyramidal Cells; Rats; Rats, Wistar; Receptors, GABA-A; Synaptic Transmission | 2006 |
Protective effect of BR-16A, a polyherbal preparation against social isolation stress: possible GABAergic mechanism.
Topics: Animals; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Female; Flumazenil; GABA Agonists; gamma-Aminobutyric Acid; Male; Mice; Motor Activity; Pain; Pentobarbital; Phytotherapy; Plant Extracts; Social Isolation; Stress, Psychological | 2006 |
Identification of structures within GABAA receptor alpha subunits that regulate the agonist action of pentobarbital.
Topics: Allosteric Regulation; Animals; Cell Line; Etomidate; GABA Agonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Mice; Pentobarbital; Protein Subunits; Receptors, GABA-A; Structure-Activity Relationship | 2006 |
Evidence that the beta-acids fraction of hops reduces central GABAergic neurotransmission.
Topics: Animals; Antidepressive Agents; Binding, Competitive; Carbon Dioxide; Central Nervous System; Cerebellum; Depression, Chemical; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Humulus; Male; Maze Learning; Motor Activity; Pentobarbital; Picrotoxin; Plant Extracts; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Seizures; Sleep; Solvents; Swimming; Synaptic Transmission | 2007 |
Barbiturate activation and modulation of GABA(A) receptors in neocortex.
Topics: Animals; Animals, Newborn; Barbiturates; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; GABA Antagonists; gamma-Aminobutyric Acid; Hypnotics and Sedatives; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Neocortex; Neurons; Patch-Clamp Techniques; Pentobarbital; Phenobarbital; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Thalamus | 2007 |
Pentobarbital enhances gamma-aminobutyric acid-mediated excitation without altering synaptic plasticity in rat hippocampus.
Topics: Adjuvants, Anesthesia; Animals; Baclofen; Bicarbonates; Bicuculline; Electric Stimulation; Excitatory Postsynaptic Potentials; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Neuronal Plasticity; Neurons; Pentobarbital; Rats; Receptors, GABA-A; Receptors, GABA-B; Synaptic Transmission; Time Factors | 2007 |
Extract of Ganoderma lucidum potentiates pentobarbital-induced sleep via a GABAergic mechanism.
Topics: Animals; Drug Synergism; Drugs, Chinese Herbal; Flumazenil; GABA Modulators; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Male; Mice; Mice, Inbred ICR; Motor Activity; Pentobarbital; Rats; Rats, Sprague-Dawley; Reishi; Sleep; Sleep, REM | 2007 |
Mesopontine tegmental anesthesia area projects independently to the rostromedial medulla and to the spinal cord.
Topics: Anesthesia; Anesthetics, Intravenous; Animals; Biomarkers; Chloral Hydrate; Cholera Toxin; Data Interpretation, Statistical; Fluorescent Dyes; gamma-Aminobutyric Acid; Laminectomy; Male; Medulla Oblongata; Microinjections; Neural Pathways; Neurons; Pentobarbital; Pons; Rats; Rats, Wistar; Receptors, GABA-A; Spinal Cord; Stilbamidines; Ventral Tegmental Area | 2007 |
Central nervous system depressant activity of an ethyl acetate extract from Ipomoea stans roots.
Topics: Acetates; Animals; Anti-Anxiety Agents; Anticonvulsants; Antidepressive Agents; Central Nervous System Depressants; Cerebral Cortex; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Ipomoea; Male; Mice; Mice, Inbred ICR; Motor Activity; Neurotransmitter Agents; Pentobarbital; Pentylenetetrazole; Plant Extracts; Plant Roots; Seizures; Solvents; Swimming | 2007 |
Homeostatic plasticity of GABAergic synaptic transmission in mice lacking GAT1.
Topics: Animals; GABA Agonists; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Homeostasis; Hypnotics and Sedatives; Inhibitory Postsynaptic Potentials; Mice; Neuronal Plasticity; Nipecotic Acids; Pentobarbital; Reaction Time; Synaptic Transmission; Tiagabine | 2007 |
Sanjoinine A isolated from Zizyphi Spinosi Semen augments pentobarbital-induced sleeping behaviors through the modification of GABA-ergic systems.
Topics: Animals; Cerebellum; Chlorides; Drug Interactions; GABA Agonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hypnotics and Sedatives; Isoenzymes; Male; Mice; Mice, Inbred ICR; Muscimol; Pentobarbital; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sleep; Ziziphus | 2007 |
Functional asymmetry of the conserved cystine loops in alphabetagamma GABA A receptors revealed by the response to GABA activation and drug potentiation.
Topics: Amino Acid Motifs; Amino Acid Sequence; Cell Line; Cystine; Diazepam; Drug Synergism; Etomidate; GABA Modulators; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Molecular Sequence Data; Patch-Clamp Techniques; Pentobarbital; Proline; Protein Conformation; Receptors, GABA-A; Receptors, GABA-B | 2008 |
Cyclopeptide alkaloid fraction from Zizyphi Spinosi Semen enhances pentobarbital-induced sleeping behaviors.
Topics: Alkaloids; Animals; Cells, Cultured; Cerebellum; Chlorides; Drug Synergism; GABA Agonists; gamma-Aminobutyric Acid; Glyceraldehyde-3-Phosphate Dehydrogenases; Hypnotics and Sedatives; Male; Mice; Mice, Inbred ICR; Muscimol; Neurons; Pentobarbital; Plant Extracts; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sleep; Synaptic Transmission; Ziziphus | 2008 |
Gamma-aminobutyric acid (GABA) and pentobarbital induce different conformational rearrangements in the GABA A receptor alpha1 and beta2 pre-M1 regions.
Topics: Amino Acid Substitution; Animals; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Ion Channel Gating; Pentobarbital; Protein Structure, Tertiary; Pyridazines; Rats; Receptors, GABA-A; Xenopus laevis | 2008 |
Neuropharmacological studies on Wedelia calendulacea Less stem extract.
Topics: Analgesics; Animals; Anticonvulsants; Avoidance Learning; Behavior, Animal; Brain; Drug Evaluation, Preclinical; Female; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Locomotion; Male; Mass Spectrometry; Mice; Motor Activity; Neuropharmacology; Pentobarbital; Pentylenetetrazole; Plant Extracts; Plant Stems; Plants, Medicinal; Rats; Sleep; Strychnine; Wedelia | 2008 |
Tyrianthinic acids from Ipomoea tyrianthina and their antimycobacterial activity, cytotoxicity, and effects on the central nervous system.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antitubercular Agents; Central Nervous System; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Ipomoea; KB Cells; Mexico; Mice; Models, Animal; Oligosaccharides; Pentobarbital; Pentylenetetrazole; Plant Roots; Plants, Medicinal; Tuberculosis | 2008 |
Distinct structural changes in the GABAA receptor elicited by pentobarbital and GABA.
Topics: Analysis of Variance; Animals; Dose-Response Relationship, Drug; Fluorometry; GABA Modulators; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Models, Molecular; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Protein Conformation; Rats; Receptors, GABA-A; Rhodamines; Xenopus laevis | 2009 |
Pentobarbital produces activation and block of {alpha}1{beta}2{gamma}2S GABAA receptors in rapidly perfused whole cells and membrane patches: divergent results can be explained by pharmacokinetics.
Topics: Animals; Binding Sites; Cell Compartmentation; Dose-Response Relationship, Drug; Feedback, Physiological; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Intracellular Space; Ion Channel Gating; Ion Transport; Models, Biological; Patch-Clamp Techniques; Pentobarbital; Pharmacokinetics; Protein Subunits; Rats; Receptors, GABA-A; Research Design | 2009 |
Activation and modulation of concatemeric GABA-A receptors expressed in human embryonic kidney cells.
Topics: Binding Sites; Cell Line; Diazepam; GABA Modulators; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Mutation; Patch-Clamp Techniques; Pentobarbital; Pregnanolone; Protein Multimerization; Protein Subunits; Receptors, GABA-A | 2009 |
Comparison of the antiepileptic properties of transmeningeally delivered muscimol, lidocaine, midazolam, pentobarbital and GABA, in rats.
Topics: Acetylcholine; Animals; Anticonvulsants; Electrodes, Implanted; Electroencephalography; gamma-Aminobutyric Acid; Lidocaine; Midazolam; Muscimol; Pentobarbital; Rats; Seizures; Somatosensory Cortex; Time Factors | 2010 |
Activation of alpha6-containing GABAA receptors by pentobarbital occurs through a different mechanism than activation by GABA.
Topics: Animals; Binding Sites; Cell Line; GABA Agonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Humans; Mutation; Patch-Clamp Techniques; Pentobarbital; Rats; Receptors, GABA-A | 2010 |
Agonist function of the recombinant alpha 4 beta 3 delta GABAA receptor is dependent on the human and rat variants of the alpha 4-subunit.
Topics: Aged; Animals; Cells, Cultured; Female; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Hippocampus; Humans; Male; Middle Aged; Oocytes; Pentobarbital; Rats; Rats, Wistar; Receptors, GABA-A; Recombinant Proteins; Xenopus | 2010 |
Photochemical proteolysis of an unstructured linker of the GABAAR extracellular domain prevents GABA but not pentobarbital activation.
Topics: Allosteric Regulation; Dose-Response Relationship, Drug; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Humans; Hydrolysis; Mutagenesis, Site-Directed; Pentobarbital; Photochemistry; Receptors, GABA-A | 2010 |
Apolipoprotein E4 causes age- and Tau-dependent impairment of GABAergic interneurons, leading to learning and memory deficits in mice.
Topics: Age Factors; Analysis of Variance; Animals; Apolipoprotein E4; Cells, Cultured; Dentate Gyrus; Electrophysiology; Female; gamma-Aminobutyric Acid; Immunohistochemistry; Interneurons; Maze Learning; Memory Disorders; Mice; Mice, Transgenic; Nerve Degeneration; Pentobarbital; Presynaptic Terminals; Statistics, Nonparametric; tau Proteins | 2010 |
Neuropharmacological properties of neurons derived from human stem cells.
Topics: Cell Differentiation; Chlordiazepoxide; Diazepam; gamma-Aminobutyric Acid; Glycine; Humans; Immunohistochemistry; Ion Channel Gating; Ligands; Mefenamic Acid; Neurons; Pentobarbital; Pregnanolone; Stem Cells; Tetraethylammonium; Tetrodotoxin | 2011 |
Propofol protects against impairment of learning-memory and imbalance of hippocampal Glu/GABA induced by electroconvulsive shock in depressed rats.
Topics: Animals; Cognition; Depression; Down-Regulation; Electroconvulsive Therapy; Electroshock; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamates; Hippocampus; Learning; Male; Memory; Memory Disorders; Pentobarbital; Propofol; Rats; Rats, Sprague-Dawley; Seizures; Up-Regulation | 2011 |
Structural link between γ-aminobutyric acid type A (GABAA) receptor agonist binding site and inner β-sheet governs channel activation and allosteric drug modulation.
Topics: Allosteric Regulation; Amino Acid Sequence; Animals; Benzodiazepines; Binding Sites; Drug Design; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Glycine; Molecular Sequence Data; Oocytes; Pentobarbital; Protein Structure, Secondary; Pyridazines; Rats; Receptors, GABA-A; Structure-Activity Relationship; Xenopus laevis | 2012 |
Antipsychotic and sedative effects of the leaf extract of Crassocephalum bauchiense (Hutch.) Milne-Redh (Asteraceae) in rodents.
Topics: Animals; Antipsychotic Agents; Apomorphine; Asteraceae; Behavior, Animal; Body Temperature; Brain; Catalepsy; Disease Models, Animal; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Flumazenil; GABA Agents; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Male; Medicine, African Traditional; Mice; Mice, Inbred Strains; Motor Activity; Pentobarbital; Phytotherapy; Plant Extracts; Plant Leaves; Psychotic Disorders; Rats, Sprague-Dawley; Receptors, GABA-A; Sleep; Valproic Acid | 2012 |
Comparative effects of pentobarbital on spontaneous and evoked transmitter release from inhibitory and excitatory nerve terminals in rat CA3 neurons.
Topics: Animals; Animals, Newborn; Biophysical Phenomena; Biophysics; CA3 Region, Hippocampal; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials; Excitatory Postsynaptic Potentials; GABA Modulators; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Neurons; Neurotransmitter Agents; Pentobarbital; Presynaptic Terminals; Rats; Rats, Wistar; Time Factors | 2013 |
The benzodiazepine diazepam potentiates responses of α1β2γ2L γ-aminobutyric acid type A receptors activated by either γ-aminobutyric acid or allosteric agonists.
Topics: Anesthetics; Animals; Binding Sites; Diazepam; Drug Synergism; Etomidate; GABA Modulators; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Patch-Clamp Techniques; Pentobarbital; Pregnanediones; Rats; Receptors, GABA-A | 2013 |
In intact islets interstitial GABA activates GABA(A) receptors that generate tonic currents in α-cells.
Topics: Animals; gamma-Aminobutyric Acid; Gene Expression Regulation; Glucagon-Secreting Cells; Ion Channel Gating; Pentobarbital; Protein Subunits; Pyridazines; Rats; Rats, Wistar; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2013 |
3,4,5-Trimethoxycinnamic acid (TMCA), one of the constituents of Polygalae Radix enhances pentobarbital-induced sleeping behaviors via GABAAergic systems in mice.
Topics: Animals; Cerebellum; Chlorides; Cinnamates; Drug Synergism; GABA Agonists; GABAergic Neurons; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hypnotics and Sedatives; Male; Mice; Motor Activity; Muscimol; Neurons; Pentobarbital; Polygala; Primary Cell Culture; Receptors, GABA-A; Sleep; Sleep Stages | 2013 |
Expression of the γ2-subunit distinguishes synaptic and extrasynaptic GABA(A) receptors in NG2 cells of the hippocampus.
Topics: Animals; Benzodiazepines; Bicuculline; Diazepam; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Muscimol; Neuroglia; Neurons; Patch-Clamp Techniques; Pentobarbital; Protein Subunits; Receptors, GABA-A; Synapses | 2013 |
Potentiating effect of glabridin on GABAA receptor-mediated responses in dorsal raphe neurons.
Topics: Animals; Anti-Anxiety Agents; Brain; Diazepam; Dose-Response Relationship, Drug; Flumazenil; GABA Agents; gamma-Aminobutyric Acid; Glycyrrhiza; Hypnotics and Sedatives; Isoflavones; Neurons; Pentobarbital; Phenols; Plant Extracts; Plant Roots; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Zolpidem | 2013 |
Synaptic-type α1β2γ2L GABAA receptors produce large persistent currents in the presence of ambient GABA and anesthetic drugs.
Topics: Anesthetics; Animals; Cell Line; Chromosome Pairing; Etomidate; gamma-Aminobutyric Acid; HEK293 Cells; Humans; Pentobarbital; Pregnanediones; Propofol; Rats; Receptors, GABA-A | 2015 |
Rescue of Methyl-CpG Binding Protein 2 Dysfunction-induced Defects in Newborn Neurons by Pentobarbital.
Topics: Adjuvants, Anesthesia; Animals; Cells, Cultured; Embryo, Mammalian; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Hippocampus; Humans; Methyl-CpG-Binding Protein 2; Mice; Nerve Net; Neurons; Pentobarbital; Rats; Rats, Long-Evans; Signal Transduction; Sodium Channel Blockers; Synapsins; Tetrodotoxin; Time Factors | 2015 |
Anticonvulsant and Sedative Effects of Eudesmin isolated from Acorus tatarinowii on mice and rats.
Topics: Acorus; Animals; Anticonvulsants; Brain; Caspase 3; Disease Models, Animal; Electroshock; Epilepsy; Furans; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Hypnotics and Sedatives; Lignans; Male; Mice; Mice, Inbred ICR; Motor Activity; Pentobarbital; Plant Extracts; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Seizures | 2015 |
Positive effects of β-amyrin on pentobarbital-induced sleep in mice via GABAergic neurotransmitter system.
Topics: Animals; Bicuculline; Brain; Dose-Response Relationship, Drug; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Mice, Inbred ICR; Molecular Structure; Oleanolic Acid; Pentobarbital; Random Allocation; Sleep; Sleep Aids, Pharmaceutical; Time Factors; Wakefulness-Promoting Agents | 2015 |
A study on quality components and sleep-promoting effects of GABA black tea.
Topics: Animals; Caffeine; Catechin; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Male; Mice; Pentobarbital; Plant Extracts; Polyphenols; Sleep; Tea | 2015 |
Enhancing GABA Signaling during Middle Adulthood Prevents Age-Dependent GABAergic Interneuron Decline and Learning and Memory Deficits in ApoE4 Mice.
Topics: Aging; Animals; Apolipoprotein E4; Female; GABA Agonists; gamma-Aminobutyric Acid; Gene Knock-In Techniques; Interneurons; Learning Disabilities; Maze Learning; Memory Disorders; Mice; Mice, Inbred C57BL; Pentobarbital; Receptors, GABA-A; Signal Transduction | 2016 |
Sleep-promoting effects of the GABA/5-HTP mixture in vertebrate models.
Topics: 5-Hydroxytryptophan; Administration, Oral; Animals; Brain; Chromatography, High Pressure Liquid; Drug Therapy, Combination; Electroencephalography; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Mice, Inbred ICR; Models, Animal; Pentobarbital; Rats, Sprague-Dawley; Receptors, GABA-A; RNA, Messenger; Sleep; Time Factors | 2016 |
Calcium and protons affect the interaction of neurotransmitters and anesthetics with anionic lipid membranes.
Topics: Acetylcholine; Anesthetics; Calcium; gamma-Aminobutyric Acid; Glutamic Acid; Hydrogen-Ion Concentration; Membranes, Artificial; Neurotransmitter Agents; Pentobarbital; Protons; Tetracaine | 2016 |
A chimeric prokaryotic-eukaryotic pentameric ligand gated ion channel reveals interactions between the extracellular and transmembrane domains shape neurosteroid modulation.
Topics: Animals; Bacterial Proteins; Cell Membrane; Chlorides; Etomidate; Extracellular Space; gamma-Aminobutyric Acid; Humans; Ligand-Gated Ion Channels; Membrane Potentials; Mutation; Neurotransmitter Agents; Oocytes; Pentobarbital; Picrotoxin; Propofol; Protein Domains; Protons; Receptors, GABA-B; Recombinant Fusion Proteins; Xenopus laevis | 2017 |
GABA Type A Receptor Activation in the Allosteric Coagonist Model Framework: Relationship between EC
Topics: Allosteric Regulation; Anesthetics; Animals; Binding Sites; Dose-Response Relationship, Drug; Drug Interactions; GABA Agonists; gamma-Aminobutyric Acid; Models, Biological; Models, Theoretical; Mutation; Oocytes; Patch-Clamp Techniques; Pentobarbital; Pregnanediones; Propofol; Receptors, GABA-A; Xenopus laevis | 2018 |
Palmatine plays a role in sedation and hypnosis by increasing 5-hydroxytryptamine.
Topics: Animals; Berberine Alkaloids; Body Weight; Brain; Cell Proliferation; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Male; Mice; PC12 Cells; Pentobarbital; Rats; Receptors, GABA; Reference Standards; Serotonin; Sleep; Time Factors | 2019 |
Topics: Animals; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Hypothalamus; Male; Mice; Mice, Inbred ICR; Moringa oleifera; Pentobarbital; Plant Extracts; Plant Oils; Receptors, GABA-A; Seeds; Sleep | 2020 |
The combined use of gamma-aminobutyric acid and walnut peptide enhances sleep in mice.
Topics: Animals; gamma-Aminobutyric Acid; Juglans; Mice; Pentobarbital; Peptides; Sleep | 2021 |
Activation of the Rat α1β2ε GABA
Topics: Animals; Cysteine; gamma-Aminobutyric Acid; Pentobarbital; Propofol; Rats; Receptors, GABA-A | 2022 |
Non-sedative cortical EEG signatures of allopregnanolone and functional comparators.
Topics: Animals; Antidepressive Agents; Diazepam; Electroencephalography; gamma-Aminobutyric Acid; Humans; Ketamine; Mice; Neurosteroids; Pentobarbital; Pregnanolone; Receptors, GABA-A | 2023 |
Zerumbone, a major sesquiterpene from Syringa pinnatifolia Hemsl., exerts the sedative effect by regulating GABAergic nervous system.
Topics: Animals; Bicuculline; Chlorides; Flumazenil; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Mice; Molecular Docking Simulation; Nervous System; Pentobarbital; Plant Extracts; Rats; Receptors, GABA-A; Sesquiterpenes; Syringa | 2023 |
Sedative-hypnotic effects of Boropinol-B on mice via activation of GABAA receptors.
Topics: Animals; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Mice; Pentobarbital; Rats; Receptors, GABA; Sleep Initiation and Maintenance Disorders | 2023 |
N-methyl-d-aspartate receptors and glycinergic transmission, respectively, mediate muscle relaxation and immobility of pentobarbital in mice.
Topics: Animals; Dizocilpine Maleate; gamma-Aminobutyric Acid; Mecamylamine; Mice; Pentobarbital; Receptors, N-Methyl-D-Aspartate; Sarcosine; Unconsciousness | 2023 |
Sleep-promoting activity of amylase-treated Ashwagandha (Withania somnifera L. Dunal) root extract via GABA receptors.
Topics: Amylases; gamma-Aminobutyric Acid; Pentobarbital; Plant Extracts; Receptors, GABA; Sleep; Sleep Initiation and Maintenance Disorders; Withania | 2023 |