pentobarbital and flurazepam

pentobarbital has been researched along with flurazepam in 41 studies

Research

Studies (41)

Timeframe	Studies, this research(%)	All Research%
pre-1990	23 (56.10)	18.7374
1990's	11 (26.83)	18.2507
2000's	4 (9.76)	29.6817
2010's	3 (7.32)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Engel, J; Fleischhauer, I; Jakovlev, V; Johanson, CE; Kleemann, A; Kutscher, B; Nickel, B; Rauer, H; Szelenyi, I; Werner, U	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Kramer, MS; Raja, R; Rosenbaum, JL	1
Borland, RG; Nicholson, AN	1
Bowery, NG; Dray, A	1
Bixler, EO; Kales, A; Kales, JD; Scharf, MB	1
Franco, S; Schlosser, W	1
Bonnet, MH; Webb, WB	1
Barnard, G; Bonnet, MH; Webb, WB	1
Shibata, S; Tominaga, K; Ueki, S; Watanabe, S	1
Bowers, BJ; Pounder, JI; Wehner, JM	1
Lindgren, S; Meyerson, B; Westerling, P	1
Farb, DH; Friedman, L; Gibbs, TT; Roca, DJ; Rozenberg, I; Schiller, GD	1
Ferrendelli, JA; Miller, JW	1
White, G	1
Friedman, DL; Redburn, DA	1
Jones, GR; Pounder, DJ	1
Holden-Dye, L; Krogsgaard-Larsen, P; Nielsen, L; Walker, RJ	1
Goodwin, GM; Gray, JA; Green, AR; Heal, DJ	1
Gale, RG; Little, HJ; Nutt, DJ; Standing, BL; Taylor, SC	1
Johanson, CE; Schuster, CR	1
Johanson, CE	1
Simmonds, MA	1
Zarkovsky, AM	1
Lindgren, S; Simmonds, MA	1
Boudinot, E; Champagnat, J; Denavit-Saubié, M; Foutz, AS; Gonsalves, SF; Morin-Surun, MP	1
Canon, J; Halperin, JM; Iorio, LC	1
Bixler, EO; Kales, A; Kales, JD; Scharf, MB; Tan, TL	1
Brucato, A; Gianguzza, eS; Provenzano, PM	1
Banerjee, U	1
Mariotti, M; Ongini, E	1
Shannon, HE	1
Hertz, L; Mukerji, S	1
Hu, XJ; Ticku, MK	1
Smart, TG; Xie, X	1
Alva, H; Blednov, YA; Harris, RA; Jung, S; Rosahl, T; Wallace, D; Whiting, PJ	1
Czajkowski, C; Sharkey, LM	1
Aller, MI; Korpi, ER; Leppä, E; Linden, AM; Rosenberg, PH; Wisden, W	1
Blednov, YA; Harris, RA; Homanics, GE; Osterndorff-Kahanek, E; Ponomarev, I	1
Benavidez, JM; Black, M; Blednov, YA; Harris, RA; Mayfield, J	1

Reviews

1 review(s) available for pentobarbital and flurazepam

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

3 trial(s) available for pentobarbital and flurazepam

Article	Year
Comparison of the residual effects of two benzodiazepines (nitrazepam and flurazepam hydrochloride) and pentobarbitone sodium on human performance. British journal of clinical pharmacology, 1975, Volume: 2, Issue:1 Topics: Adult; Anti-Anxiety Agents; Flurazepam; Humans; Male; Motor Skills; Nitrazepam; Pentobarbital; Placebos; Reaction Time; Regression Analysis; Task Performance and Analysis	1975
Effectiveness of hypnotic drugs with prolonged use: flurazepam and pentobarbital. Clinical pharmacology and therapeutics, 1975, Volume: 18, Issue:3 Topics: Adult; Anti-Anxiety Agents; Clinical Trials as Topic; Drug Evaluation; Electroencephalography; Flurazepam; Humans; Middle Aged; Pentobarbital; Sleep Initiation and Maintenance Disorders; Sleep Stages; Sleep, REM; Time Factors	1975
Effect of flurazepam, pentobarbital, and caffeine on arousal threshold. Sleep, 1979,Spring, Volume: 1, Issue:3 Topics: Adult; Arousal; Auditory Threshold; Caffeine; Flurazepam; Humans; Male; Pentobarbital; Sleep Stages; Wakefulness	1979

Other Studies

37 other study(ies) available for pentobarbital and flurazepam

Article	Year
Chemistry and pharmacology of the non-benzodiazepine anxiolytic enciprazine and related compounds. Journal of medicinal chemistry, 1990, Volume: 33, Issue:11 Topics: Aggression; Animals; Anti-Anxiety Agents; Behavior, Animal; Chemical Phenomena; Chemistry; Exploratory Behavior; Female; Male; Mice; Molecular Structure; Piperazines; Rats; Self Administration; Structure-Activity Relationship; Substance-Related Disorders	1990
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Resin hemoperfusion for acute drug intoxication. Archives of internal medicine, 1976, Volume: 136, Issue:3 Topics: Adult; Aged; Amobarbital; Female; Flurazepam; Glutethimide; Humans; Middle Aged; Pentobarbital; Poisoning; Renal Dialysis; Resins, Plant; Secobarbital; Suicide, Attempted; Urea	1976
Reversal of the action of amino acid antagonists by barbiturates and other hypnotic drugs. British journal of pharmacology, 1978, Volume: 63, Issue:1 Topics: Aminobutyrates; Animals; Benzodiazepines; Bicuculline; Central Nervous System; Chlordiazepoxide; Dose-Response Relationship, Drug; Drug Interactions; Flurazepam; GABA Antagonists; Hypnotics and Sedatives; Male; Pentobarbital; Rats; Secobarbital; Strychnine; Synaptic Transmission	1978
Modification of GABA-mediated depolarization of the cat ganglion by pentobarbital and two benzodiazepines. Neuropharmacology, 1979, Volume: 18, Issue:4 Topics: Animals; Benzodiazepines; Bicuculline; Cats; Flurazepam; gamma-Aminobutyric Acid; Ganglia, Spinal; Pentobarbital; Picrotoxin	1979
The return to sleep. Biological psychology, 1979, Volume: 8, Issue:3 Topics: Adult; Arousal; Caffeine; Flurazepam; Humans; Male; Pentobarbital; Reaction Time; Sleep Stages; Wakefulness	1979
Effects of inhibitory and excitatory drugs on the metabolic rhythm of the hamster suprachiasmatic nucleus in vitro. European journal of pharmacology, 1992, Jun-24, Volume: 217, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Circadian Rhythm; Cricetinae; Deoxyglucose; Dose-Response Relationship, Drug; Flurazepam; Glutamates; Glutamic Acid; Male; Mesocricetus; Muscimol; Neurons; Pentobarbital; Potassium Chloride; Suprachiasmatic Nucleus; Tetrodotoxin	1992
The use of recombinant inbred strains to study mechanisms of drug action. Journal of addictive diseases, 1991, Volume: 10, Issue:1-2 Topics: Animals; Arousal; Brain; Central Nervous System Depressants; Convulsants; Dose-Response Relationship, Drug; Ethanol; Flurazepam; Mice; Mice, Inbred Strains; Pentobarbital; Phenobarbital; Receptors, GABA-A; Recombination, Genetic; Selection, Genetic; Sleep Stages	1991
Functional changes in GABAA receptor stimulation during the oestrous cycle of the rat. British journal of pharmacology, 1991, Volume: 103, Issue:2 Topics: Animals; Chlorides; Estrogens; Estrus; Female; Flurazepam; In Vitro Techniques; Neurons, Afferent; Ovariectomy; Pentobarbital; Picrotoxin; Potassium; Progesterone; Rats; Rats, Inbred Strains; Receptors, GABA-A	1991
gamma-Aminobutyric acidA receptor regulation in culture: altered allosteric interactions following prolonged exposure to benzodiazepines, barbiturates, and methylxanthines. Molecular pharmacology, 1990, Volume: 37, Issue:5 Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Allosteric Regulation; Animals; Barbital; Barbiturates; Brain; Caffeine; Cells, Cultured; Chick Embryo; Flumazenil; Flunitrazepam; Flurazepam; gamma-Aminobutyric Acid; Kinetics; Neurons; Pentobarbital; Receptors, GABA-A; Tetrodotoxin; Theophylline; Veratridine	1990
Characterization of GABAergic seizure regulation in the midline thalamus. Neuropharmacology, 1990, Volume: 29, Issue:7 Topics: Animals; Baclofen; Bicuculline; Electroencephalography; Epilepsy; Female; Flurazepam; gamma-Aminobutyric Acid; Pentobarbital; Pentylenetetrazole; Piperidines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Thalamic Nuclei	1990
GABAA-receptor-activated current in dorsal root ganglion neurons freshly isolated from adult rats. Journal of neurophysiology, 1990, Volume: 64, Issue:1 Topics: Animals; Flurazepam; gamma-Aminobutyric Acid; Ganglia, Spinal; In Vitro Techniques; Male; Membrane Potentials; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A	1990
Evidence for functionally distinct subclasses of gamma-aminobutyric acid receptors in rabbit retina. Journal of neurochemistry, 1990, Volume: 55, Issue:4 Topics: Acetylcholine; Amino Acids; Amino Acids, Neutral; Animals; Baclofen; Binding, Competitive; Cell Fractionation; Flurazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Light; Models, Theoretical; Pentobarbital; Picrotoxin; Rabbits; Receptors, GABA-A; Retina	1990
Post-mortem drug redistribution--a toxicological nightmare. Forensic science international, 1990, Volume: 45, Issue:3 Topics: Adult; Amobarbital; Barbiturates; Clomipramine; Doxepin; Female; Flurazepam; Humans; Imipramine; Male; Middle Aged; Pentobarbital; Postmortem Changes; Secobarbital; Suicide; Tissue Distribution	1990
GABA receptors on the somatic muscle cells of the parasitic nematode, Ascaris suum: stereoselectivity indicates similarity to a GABAA-type agonist recognition site. British journal of pharmacology, 1989, Volume: 98, Issue:3 Topics: Animals; Ascaris; Baclofen; Binding, Competitive; Dieldrin; Electric Stimulation; Flurazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Muscles; Pentobarbital; Receptors, GABA-A; Stereoisomerism	1989
Hypothermia induced by baclofen, a possible index of GABAB receptor function in mice, is enhanced by antidepressant drugs and ECS. British journal of pharmacology, 1987, Volume: 92, Issue:4 Topics: 5,7-Dihydroxytryptamine; Amitriptyline; Animals; Antidepressive Agents; Baclofen; Body Temperature; Electroshock; Flurazepam; Hypnotics and Sedatives; Injections, Intraperitoneal; Injections, Intraventricular; Male; Mice; Neural Pathways; Pentobarbital; Receptors, GABA-A	1987
Changes in benzodiazepine/GABA receptor complex function in benzodiazepine-tolerant mice. Psychopharmacology, 1988, Volume: 95, Issue:3 Topics: Animals; Anticonvulsants; Bicuculline; Body Temperature; Drug Tolerance; Flurazepam; gamma-Aminobutyric Acid; Infusions, Intravenous; Male; Mice; Motor Activity; Pentobarbital; Picrotoxin; Receptors, GABA-A; Seizures; Time Factors	1988
The effects of Ro 15-1788 on anxiolytic self-administration in the rhesus monkey. Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:4 Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Drug Interactions; Female; Flumazenil; Flurazepam; Lorazepam; Macaca mulatta; Male; Pentobarbital; Reinforcement, Psychology; Self Administration	1986
Benzodiazepine self-administration in rhesus monkeys: estazolam, flurazepam and lorazepam. Pharmacology, biochemistry, and behavior, 1987, Volume: 26, Issue:3 Topics: Animals; Anti-Anxiety Agents; Estazolam; Female; Flurazepam; Infusions, Intravenous; Lorazepam; Macaca mulatta; Male; Pentobarbital; Self Administration; Time Factors	1987
Antagonism of flurazepam and other effects of Ro15-1788, PK8165 and Ro5-4864 on the GABA-A receptor complex in rat cuneate nucleus. European journal of pharmacology, 1985, Oct-29, Volume: 117, Issue:1 Topics: Animals; Anticonvulsants; Benzodiazepinones; Drug Synergism; Flumazenil; Flurazepam; In Vitro Techniques; Male; Medulla Oblongata; Muscimol; Pentobarbital; Picrotoxin; Quinolines; Rats; Rats, Inbred Strains; Receptors, GABA-A	1985
The inhibitory effect of endogenous convulsants quinolinic acid and kynurenine on the pentobarbital stimulation of [3H]flunitrazepam binding. Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:5 Topics: Animals; Anticonvulsants; Flurazepam; Kinetics; Kynurenine; Male; Pentobarbital; Picolinic Acids; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, GABA-A	1986
Adaptation of the GABAA-receptor complex in rat brain during chronic elevation of GABA by ethanolamine O-sulphate. British journal of pharmacology, 1987, Volume: 91, Issue:3 Topics: 4-Aminobutyrate Transaminase; Animals; Brain Chemistry; Ethanolamines; Flurazepam; gamma-Aminobutyric Acid; Muscimol; Nipecotic Acids; Pentobarbital; Picrotoxin; Potassium; Proline; Rats; Rats, Inbred Strains; Receptors, GABA-A	1987
Effects of pentobarbital and flurazepam on respiratory neurons in undrugged cats. Pharmacology, biochemistry, and behavior, 1987, Volume: 26, Issue:4 Topics: Animals; Cats; Decerebrate State; Electrophysiology; Flurazepam; gamma-Aminobutyric Acid; Neurons; Pentobarbital; Respiratory System	1987
Preclinical evaluation of behavioral deficits following hypnotic drug treatment. Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:4 Topics: Animals; Cebus; Conditioning, Operant; Discrimination Learning; Drug Evaluation, Preclinical; Flurazepam; Hypnotics and Sedatives; Male; Pentobarbital; Psychomotor Disorders; Triazolam	1986
Chronic hypnotic-drug use. Ineffectiveness, drug-withdrawal insomnia, and dependence. JAMA, 1974, Feb-04, Volume: 227, Issue:5 Topics: Adult; Age Factors; Aged; Amobarbital; Chloral Hydrate; Chronic Disease; Dreams; Drug Therapy, Combination; Female; Flurazepam; Humans; Hypnotics and Sedatives; Male; Middle Aged; Pentobarbital; Secobarbital; Sleep Deprivation; Sleep Initiation and Maintenance Disorders; Sleep, REM; Sodium; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors; Wakefulness	1974
[Influence of arginine pyroglutamate on pentobarbital anesthesia]. Bollettino della Societa italiana di biologia sperimentale, 1974, Nov-15, Volume: 50, Issue:21 Topics: Anesthesia, General; Animals; Arginine; Flurazepam; Male; Medazepam; Pentobarbital; Pyrrolidinones; Pyrrolidonecarboxylic Acid; Rats	1974
Programmed self-administration of potentially addictive drugs in young rats and its effects on learning. Psychopharmacologia, 1974, Volume: 38, Issue:2 Topics: Amphetamine; Animals; Avoidance Learning; Behavior, Animal; Drug Tolerance; Ethanol; Extinction, Psychological; Female; Flurazepam; Humans; Learning; Male; Meprobamate; Morphine; Motor Activity; Nitrazepam; Pentobarbital; Phenobarbital; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders; Water	1974
Differential effects of benzodiazepines on EEG activity and hypnogenic mechanisms of the brain stem in cats. Archives internationales de pharmacodynamie et de therapie, 1983, Volume: 264, Issue:2 Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Brain Stem; Cats; Decerebrate State; Diazepam; Electroencephalography; Flurazepam; Pentobarbital; Sleep	1983
Stimulus control by diazepam of behavior maintained under fixed-ratio stimulus-shock termination schedules in rats. Pharmacology, biochemistry, and behavior, 1984, Volume: 20, Issue:5 Topics: Animals; Behavior, Animal; Conditioning, Operant; Cyproheptadine; Diazepam; Discrimination, Psychological; Electroshock; Flurazepam; Male; Pentobarbital; Rats; Rats, Inbred F344; Reinforcement Schedule	1984
Diazepam receptors on mouse astrocytes in primary cultures: displacement by pharmacologically active concentrations of benzodiazepines or barbiturates. Canadian journal of physiology and pharmacology, 1980, Volume: 58, Issue:2 Topics: Animals; Astrocytes; Barbiturates; Benzodiazepines; Binding Sites; Binding, Competitive; Cells, Cultured; Clonazepam; Diazepam; Flurazepam; Mice; Pentobarbital; Phenobarbital; Receptors, Drug	1980
Chronic flurazepam treatment produces decreased efficacy of the benzodiazepine ligands and pentobarbital with gamma-aminobutyric acidA receptors in cortical neurons. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:2 Topics: Animals; Benzodiazepines; Biological Transport; Cells, Cultured; Cerebral Cortex; Chlorides; Female; Flumazenil; Flurazepam; Ligands; Male; Mice; Mice, Inbred C57BL; Neurons; Pentobarbital; Receptors, GABA	1994
Properties of GABA-mediated synaptic potentials induced by zinc in adult rat hippocampal pyramidal neurones. The Journal of physiology, 1993, Volume: 460 Topics: Action Potentials; Animals; Bicuculline; Culture Techniques; Flurazepam; gamma-Aminobutyric Acid; Hippocampus; Male; Membrane Potentials; Pentobarbital; Picrotoxin; Rats; Synapses; Synaptic Transmission; Zinc	1993
Deletion of the alpha1 or beta2 subunit of GABAA receptors reduces actions of alcohol and other drugs. The Journal of pharmacology and experimental therapeutics, 2003, Volume: 304, Issue:1 Topics: Animals; Behavior, Animal; Brain; Central Nervous System Depressants; Chlorides; Ethanol; Etomidate; Female; Flurazepam; GABA Agonists; GABA Modulators; Gene Deletion; Hypnotics and Sedatives; Isoxazoles; Male; Mice; Mice, Knockout; Pentobarbital; Postural Balance; Pyridines; Receptors, GABA; Receptors, GABA-A; Sex Characteristics; Sleep; Time Factors; Zolpidem	2003
Individually monitoring ligand-induced changes in the structure of the GABAA receptor at benzodiazepine binding site and non-binding-site interfaces. Molecular pharmacology, 2008, Volume: 74, Issue:1 Topics: Animals; Benzodiazepines; Binding Sites; Cysteine; Dose-Response Relationship, Drug; Electrophysiology; Female; Flumazenil; Flurazepam; GABA Agonists; GABA Antagonists; GABA Modulators; Inhibitory Concentration 50; Ligands; Microinjections; Muscimol; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Pentobarbital; Pyridazines; Rats; Receptors, GABA-A; Xenopus	2008
K+ channel TASK-1 knockout mice show enhanced sensitivities to ataxic and hypnotic effects of GABA(A) receptor ligands. The Journal of pharmacology and experimental therapeutics, 2008, Volume: 327, Issue:1 Topics: Animals; Anti-Anxiety Agents; Ataxia; Benzodiazepines; Brain; Diazepam; Female; Flurazepam; Hypnotics and Sedatives; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Nerve Tissue Proteins; Pentobarbital; Potassium Channels, Tandem Pore Domain; Propofol; Protein Kinase C; Receptors, GABA-A; Sex Factors; Spinal Cord	2008
Testing the silence of mutations: Transcriptomic and behavioral studies of GABA(A) receptor α1 and α2 subunit knock-in mice. Neuroscience letters, 2011, Jan-13, Volume: 488, Issue:1 Topics: Animals; Behavior, Animal; Cytoskeletal Proteins; Flurazepam; GABA Modulators; Gene Expression Profiling; Gene Expression Regulation; Mice; Mice, Transgenic; Movement Disorders; Mutation; Nerve Tissue Proteins; Oligonucleotide Array Sequence Analysis; Pentobarbital; Proto-Oncogene Proteins c-fos; Receptors, GABA-A	2011
Role of interleukin-1 receptor signaling in the behavioral effects of ethanol and benzodiazepines. Neuropharmacology, 2015, Volume: 95 Topics: Alcohol Drinking; Animals; Avoidance Learning; Behavior, Animal; Benzodiazepines; Ethanol; Female; Flurazepam; Hypnotics and Sedatives; Interleukin 1 Receptor Antagonist Protein; Ketamine; Male; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Pentobarbital; Receptors, Interleukin-1 Type I; Severity of Illness Index; Substance Withdrawal Syndrome; Taste Perception	2015