pentobarbital and droloxifene

pentobarbital has been researched along with droloxifene in 2 studies

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Dehal, SS; Kupfer, D1

Other Studies

2 other study(ies) available for pentobarbital and droloxifene

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Cytochrome P-450 3A and 2D6 catalyze ortho hydroxylation of 4-hydroxytamoxifen and 3-hydroxytamoxifen (droloxifene) yielding tamoxifen catechol: involvement of catechols in covalent binding to hepatic proteins.
    Drug metabolism and disposition: the biological fate of chemicals, 1999, Volume: 27, Issue:6

    Topics: Animals; Biotransformation; Catechols; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Estrogen Antagonists; Humans; Hydroxylation; In Vitro Techniques; Liver; Mixed Function Oxygenases; Pentobarbital; Protein Binding; Rats; Rats, Sprague-Dawley; Tamoxifen

1999