pentobarbital and cimetidine

pentobarbital has been researched along with cimetidine in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199014 (56.00)18.7374
1990's4 (16.00)18.2507
2000's5 (20.00)29.6817
2010's2 (8.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Lombardo, F; Obach, RS; Waters, NJ1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Fujihara, A; Kamato, T; Miyata, K; Takeda, M1
Cohen, AF; de Boer, A; Edelbroek, PM; Hoogkamer, JF; Kroon, C; Schoemaker, HC; van der Meer, EJ1
Ikediobi, CO; Kwanashie, HO; Osuide, G; Wambebe, C2
Kuroiwa, Y; Misawa, S; Nakamura, K; Tanaka, E1
Morita, K; Ono, T; Shimakawa, H1
Hatakeyama, H; Hirose, K; Jyoyama, H; Matsubara, T; Otsubo, S; Touchi, A1
Gillespie, WR; Veng-Pedersen, P1
Brent, PJ; Dosen, PJ; Gerkens, JF; Henry, DA1
Iba, MM1
Bradley, EL; Fowler, KC; Gelman, S; Tverskoy, M1
Bell, JA; Gower, AJ; Martin, LE; Mills, EN; Smith, WP1
Hino, T; Ito, Y; Kunieda, T; Ohashi, H; Sakata, K; Tsuchiya, J1
Baldinus, JG; Lofton, FT; Mayron, D; Yuhas, EM1
Innes, DL; Tansy, MF1
Breckenridge, AM; Challiner, M; Park, BK; Serlin, MJ; Turcan, PA1
Ali, BH; Banna, NR; Bashir, AK; Tanira, MO1
Czuprynski, CJ; Faith, NG; Neudeck, B; Steinberg, H1
Honda, K; Inomata, S; Misawa, S; Nagashima, A; Tanaka, E1

Reviews

1 review(s) available for pentobarbital and cimetidine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for pentobarbital and cimetidine

ArticleYear
Detection of drug interactions with single dose acenocoumarol: new screening method?
    International journal of clinical pharmacology, therapy, and toxicology, 1990, Volume: 28, Issue:8

    Topics: Acenocoumarol; Adult; Biological Availability; Blood Coagulation; Cimetidine; Double-Blind Method; Drug Interactions; Half-Life; Humans; Male; Pentobarbital

1990

Other Studies

23 other study(ies) available for pentobarbital and cimetidine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Cardiovascular and bronchial actions of famotidine in anesthetized dogs.
    Arzneimittel-Forschung, 1990, Volume: 40, Issue:11

    Topics: Airway Resistance; Anesthesia; Animals; Bronchi; Cimetidine; Dogs; Electrocardiography; Famotidine; Female; Halothane; Heart; Hemodynamics; Histamine; Male; Nitrous Oxide; Pentobarbital; Propranolol

1990
Dose-related and other effects of maternal cimetidine pretreatment during lactation on drug metabolism in mouse dams and pups.
    Biology of the neonate, 1990, Volume: 57, Issue:6

    Topics: Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Animals, Newborn; Aryl Hydrocarbon Hydroxylases; Cimetidine; Dose-Response Relationship, Drug; Female; Lactation; Male; Mice; Mice, Inbred BALB C; Pentobarbital

1990
The effect of H2-receptor antagonists on antipyrine and pentobarbital metabolism in male and female rats.
    Japanese journal of pharmacology, 1988, Volume: 46, Issue:1

    Topics: Animals; Antipyrine; Cimetidine; Famotidine; Female; Histamine H2 Antagonists; Male; Microsomes, Liver; Mixed Function Oxygenases; Pentobarbital; Ranitidine; Rats; Rats, Inbred Strains; Sex Factors; Thiazoles

1988
Effects of maternally administered cimetidine during lactation on the development of drug metabolizing enzymes in mouse pups.
    Biochemical pharmacology, 1989, Jan-01, Volume: 38, Issue:1

    Topics: Aminopyrine N-Demethylase; Animals; Animals, Newborn; Cimetidine; Female; Lactation; Male; Mice; Mice, Inbred BALB C; Milk; Pentobarbital; Pregnancy; Sex Factors

1989
Effects of ozagrel (OKY-046), a thromboxane synthase inhibitor, on oxidative drug-metabolizing enzymes in mouse hepatic microsomes.
    Journal of pharmacobio-dynamics, 1988, Volume: 11, Issue:7

    Topics: Acrylates; Animals; Binding, Competitive; Cimetidine; Cytochrome P-450 Enzyme System; Male; Methacrylates; Mice; Mice, Inbred Strains; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Pentobarbital; Sleep; Spectrophotometry; Steroid 16-alpha-Hydroxylase; Thromboxane-A Synthase

1988
[Effect of the nonsteroidal anti-inflammatory drug 480156-S on hepatic drug-metabolizing activity and pharmacological action of diazepam and pentobarbital in rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1988, Volume: 92, Issue:4

    Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cimetidine; Cytochrome P-450 Enzyme System; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Ibuprofen; Liver; Male; Oxygenases; Pentobarbital; Phenylpropionates; Rats; Rats, Inbred Strains

1988
Theorems and implications of a model-independent elimination/distribution function decomposition of linear and some nonlinear drug dispositions. IV. Exact relationship between the terminal log-linear slope parameter beta and drug clearance.
    Journal of pharmacokinetics and biopharmaceutics, 1987, Volume: 15, Issue:3

    Topics: Cimetidine; Diazepam; Humans; Injections, Intravenous; Mathematics; Models, Biological; Pentobarbital; Pharmacokinetics; Software; Tissue Distribution

1987
Omeprazole: effects on oxidative drug metabolism in the rat.
    Clinical and experimental pharmacology & physiology, 1986, Volume: 13, Issue:5

    Topics: Aminopyrine; Animals; Anti-Ulcer Agents; Benzimidazoles; Cimetidine; Drug Interactions; Male; Omeprazole; Oxidation-Reduction; Pentobarbital; Rats; Rats, Inbred Strains; Sleep

1986
Decreased duration of pentobarbital anesthesia and increased pentobarbital metabolism in immature rats perinatally exposed to cimetidine.
    Biochemical pharmacology, 1986, Jan-15, Volume: 35, Issue:2

    Topics: Anesthesia; Animals; Animals, Newborn; Cimetidine; Cytochrome P-450 Enzyme System; Female; Fetus; Male; Maternal-Fetal Exchange; Microsomes, Liver; Pentobarbital; Pregnancy; Rats; Sex Factors

1986
Influence of fentanyl and morphine on intestinal circulation.
    Anesthesia and analgesia, 1985, Volume: 64, Issue:6

    Topics: Animals; Blood Gas Analysis; Cesium Radioisotopes; Cimetidine; Dogs; Drug Interactions; Fentanyl; Hydrogen-Ion Concentration; Injections, Intravenous; Intestine, Small; Microspheres; Morphine; Oxygen Consumption; Pentobarbital; Phentolamine; Promethazine; Radioisotopes; Regional Blood Flow; Rubidium; Vascular Resistance; Vasoconstriction

1985
Interaction of H2-receptor antagonists with drug-metabolizing enzymes.
    Biochemical Society transactions, 1981, Volume: 9, Issue:1

    Topics: Animals; Cimetidine; Cytochrome P-450 Enzyme System; Furans; Guanidines; Histamine H2 Antagonists; Male; Microsomes, Liver; Pentobarbital; Ranitidine; Rats; Sleep

1981
Stress ulcer accompanying subarachnoid hemorrhage--a new rat model.
    The Japanese journal of surgery, 1983, Volume: 13, Issue:4

    Topics: Animals; Cimetidine; Diazepam; Disease Models, Animal; Gastric Mucosa; Male; Pentobarbital; Phenytoin; Rats; Rats, Inbred Strains; Stomach Ulcer; Stress, Physiological; Subarachnoid Hemorrhage

1983
Cimetidine hydrochloride compatibility with preoperative medications.
    American journal of hospital pharmacy, 1981, Volume: 38, Issue:8

    Topics: Atropine; Cimetidine; Drug Incompatibility; Drug Stability; Guanidines; Hydrogen-Ion Concentration; Pentobarbital; Premedication; Temperature; Time Factors

1981
Gastric mucosal ulceration associated with electrochemical stimulation of the limbic brain.
    Brain research bulletin, 1980, Volume: 5 Suppl 1

    Topics: Animals; Atropine; Chlorpromazine; Cimetidine; Electric Stimulation; Female; Gastric Mucosa; Limbic System; Male; Pentobarbital; Rats; Stomach Ulcer; Tetraethylammonium Compounds; Vagotomy

1980
Cimetidine potentiates the anticoagulant effect of warfarin by inhibition of drug metabolism.
    Biochemical pharmacology, 1980, Jul-01, Volume: 29, Issue:13

    Topics: Animals; Blood Coagulation; Cimetidine; Drug Synergism; Guanidines; Kinetics; Liver; Male; Paralysis; Pentobarbital; Rats; Time Factors; Warfarin; Zoxazolamine

1980
Central nervous system activity of Rhazya stricta (Decne) in mice.
    Clinical and experimental pharmacology & physiology, 1995, Volume: 22, Issue:4

    Topics: Abdomen; Analgesia; Animals; Behavior, Animal; Body Temperature; Central Nervous System; Cimetidine; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Hypnotics and Sedatives; Male; Medicine, Arabic; Mice; Motor Activity; Naloxone; Pentobarbital; Picrotoxin; Plant Extracts; Plant Leaves; Plants, Medicinal; Seizures; Sleep; Tail

1995
Sodium pentobarbital anesthesia transiently enhances the severity of infection following intragastric, but not intravenous, inoculation of Listeria monocytogenes in mice.
    Microbial pathogenesis, 2003, Volume: 35, Issue:2

    Topics: Anesthesia; Animals; Anti-Ulcer Agents; Antidiarrheals; Cell Culture Techniques; Cell Line; Cimetidine; Colony Count, Microbial; Gastrointestinal Diseases; Humans; Hypnotics and Sedatives; Immunity, Innate; Listeria monocytogenes; Listeriosis; Liver; Loperamide; Mice; Omeprazole; Pentobarbital; Spleen

2003
A study of the in vitro interaction between lidocaine and premedications using human liver microsomes.
    Journal of clinical pharmacy and therapeutics, 2005, Volume: 30, Issue:2

    Topics: Animals; Cimetidine; Clonidine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Ketoconazole; Lidocaine; Microsomes, Liver; Midazolam; Neuromuscular Depolarizing Agents; Pentobarbital; Pharmacogenetics; Premedication; Rats; Theophylline; Thiamylal

2005