pentobarbital and alphaxalone

pentobarbital has been researched along with alphaxalone in 45 studies

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-19909 (20.00)18.7374
1990's24 (53.33)18.2507
2000's7 (15.56)29.6817
2010's5 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Altomare, C; Biggio, G; Franco, M; Latrofa, A; Liso, G; Sanna, E; Trapani, G; Usala, M1
Asproni, B; Biggio, G; Busonero, F; Cerri, R; Mascia, MP; Pau, A; Sanna, E; Sanna, S; Talani, G1
Bedoya, M; Decher, N; González, W; Kiper, AK; Ramírez, D; Rinné, S1
Smaje, JC1
Richards, CD; Smaje, JC1
Bertrand, PP; Galligan, JJ1
Bowers, BJ; Wehner, JM1
Prince, RJ; Simmonds, MA2
Hadingham, KL; Horne, AL; Kemp, JA; Macaulay, AJ; Whiting, P1
Biggio, G; Concas, A; Maciocco, E; Mascia, MP; Santoro, G1
Biggio, G; Concas, A; Mascia, MP; Sanna, E; Santoro, G; Serra, M1
Ahmed, F; Lundin, LG; Shire, JG1
Marshall, JM1
Gavin, JB; Sage, MD; West, EJ1
Harrison, NL; Simmonds, MA1
Cullen, KD; Martin, RJ2
Bertuglia, S; Colantuoni, A; Intaglietta, M1
Barker, JL; Dunlap, VS; Valeyev, AY1
Bormann, J; Feigenspan, A; Wässle, H1
Harris, BD; Moody, EJ; Skolnick, P; Wong, G1
Biggio, G; Concas, A; Dazzi, L; Maciocco, E; Mascia, MP; Santoro, G1
Allen, SL; Brammer, A; West, CD1
Jussofie, A1
Hadingham, KL; Harkness, PC; Horne, AL; Kemp, JA; Whiting, P1
Barker, JL; Cruciani, RA; Lange, GD; Mahan, LC; Smallwood, VV; Valeyev, AY1
Biggio, G; Ghiani, CA; Maciocco, E; Sanna, E; Serra, M; Tuligi, G1
Coderre, TJ; Gilron, I1
Bracamontes, J; Steinbach, JH; Ueno, S; Weiss, DS; Zorumski, C1
Greenfield, LJ; Macdonald, RL; Neelands, TR; Turner, RS; Zhang, J1
Banerjee, PK; Brailowsky, S; Olsen, RW; Snead, OC; Tillakaratne, NJ; Tobin, AJ1
Coderre, TJ; Gilron, I; Quirion, R1
Davidoff, RA; Hackman, JC; Holohean, AM; Katz, JL; Valeyev, AY; Wood, PM1
Chen, CL; Chiu, TH; Yang, YR1
Carlson, BX; Engblom, AC; Kristiansen, U; Olsen, RW; Schousboe, A1
Adkins, CE; Bonnert, TP; Gonzalez, JE; Haldon, C; Kerby, J; McKernan, RM; Oades, K; Pillai, GV; Simpson, PB; Whiting, PJ1
Chang, CS; Olcese, R; Olsen, RW1
Asproni, B; Biggio, G; Busonero, F; Cerri, R; Maciocco, E; Mascia, MP; Pau, A; Sanna, E; Talani, G1
Chen, CL; Chiu, TH; Tang, JS; Yang, YR1
France, CP; Javors, MA; McMahon, LR1
Hall, WJ; Markos, F; Ruane-O'Hora, T1
Akk, G; Eaton, MM; Li, P; Steinbach, JH1
Akk, G; Li, P1
Akk, G; Germann, AL; Shin, DJ; Steinbach, JH1

Reviews

1 review(s) available for pentobarbital and alphaxalone

ArticleYear
TASK Channels Pharmacology: New Challenges in Drug Design.
    Journal of medicinal chemistry, 2019, 11-27, Volume: 62, Issue:22

    Topics: Animals; Drug Design; Drug Discovery; Humans; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Tandem Pore Domain

2019

Other Studies

44 other study(ies) available for pentobarbital and alphaxalone

ArticleYear
Propofol analogues. Synthesis, relationships between structure and affinity at GABAA receptor in rat brain, and differential electrophysiological profile at recombinant human GABAA receptors.
    Journal of medicinal chemistry, 1998, May-21, Volume: 41, Issue:11

    Topics: Anesthetics, Intravenous; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chloride Channel Agonists; Female; Humans; In Vitro Techniques; Oocytes; Patch-Clamp Techniques; Propofol; Rats; Receptors, GABA-A; Recombinant Proteins; Structure-Activity Relationship; Xenopus laevis

1998
Synthesis, structure-activity relationships at the GABA(A) receptor in rat brain, and differential electrophysiological profile at the recombinant human GABA(A) receptor of a series of substituted 1,2-diphenylimidazoles.
    Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7

    Topics: Amino Acid Sequence; Animals; Behavior, Animal; Brain; Female; GABA-A Receptor Agonists; Humans; Imidazoles; In Vitro Techniques; Male; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Protein Subunits; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Recombinant Proteins; Reflex; Stereoisomerism; Structure-Activity Relationship; Xenopus laevis

2005
General anaesthetics and the acetylcholine-sensitivity of cortical neurons.
    British journal of pharmacology, 1976, Volume: 58, Issue:3

    Topics: Acetylcholine; Anesthetics; Animals; Ether; Guinea Pigs; Halothane; Hydroxysteroids; In Vitro Techniques; Methoxyflurane; Neurons; Pentobarbital; Pregnanediones; Time Factors; Trichloroethylene

1976
Anaesthetics depress the sensitivity of cortical neurones to L-glutamate.
    British journal of pharmacology, 1976, Volume: 58, Issue:3

    Topics: Acetylcholine; Anesthetics; Animals; Cerebral Cortex; Depression, Chemical; Ether; Evoked Potentials; Glutamates; Guinea Pigs; Halothane; Hydroxysteroids; In Vitro Techniques; Magnesium; Methoxyflurane; Neurons; Pentobarbital; Pregnanediones; Trichloroethylene

1976
Alfaxalone, pentobarbital and diazepam potentiate gamma-aminobutyric acid-induced depolarizations in single myenteric neurons of guinea pig intestine.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 262, Issue:2

    Topics: Anesthetics; Animals; Diazepam; Drug Synergism; gamma-Aminobutyric Acid; Guinea Pigs; Hydrocortisone; Intestines; Male; Membrane Potentials; Muscimol; Pentobarbital; Pregnanediones; Receptors, GABA-A

1992
Biochemical and behavioral effects of steroids on GABAA receptor function in long- and short-sleep mice.
    Brain research bulletin, 1992, Volume: 29, Issue:1

    Topics: Anesthetics; Animals; Behavior, Animal; Brain Chemistry; Chlorides; Desoxycorticosterone; Ethanol; Flunitrazepam; Male; Mice; Mice, Inbred Strains; Pentobarbital; Pregnanediones; Pregnenolone; Receptors, GABA-A; Sleep; Species Specificity; Steroids

1992
Temperature and anion dependence of allosteric interactions at the gamma-aminobutyric acid-benzodiazepine receptor.
    Biochemical pharmacology, 1992, Oct-06, Volume: 44, Issue:7

    Topics: Animals; Anions; Binding, Competitive; Brain Chemistry; Drug Interactions; Flunitrazepam; Male; Pentobarbital; Pregnanediones; Propofol; Rats; Rats, Wistar; Receptors, GABA-A; Temperature

1992
Propofol potentiates the binding of [3H]flunitrazepam to the GABAA receptor complex.
    Brain research, 1992, Nov-20, Volume: 596, Issue:1-2

    Topics: Animals; Binding, Competitive; Drug Synergism; Flunitrazepam; Male; Pentobarbital; Pregnanediones; Propofol; Rats; Rats, Wistar; Receptors, GABA-A; Tritium

1992
The pharmacology of recombinant GABAA receptors containing bovine alpha 1, beta 1, gamma 2L sub-units stably transfected into mouse fibroblast L-cells.
    British journal of pharmacology, 1992, Volume: 107, Issue:3

    Topics: Animals; Chlorides; GABA Antagonists; gamma-Aminobutyric Acid; L Cells; Ligands; Mice; Pentobarbital; Pregnanediones; Receptors, GABA-A; Recombinant Proteins; Transfection

1992
The general anesthetic propofol: a biochemical tool to study the function of the GABA-coupled chloride channel.
    Clinical neuropharmacology, 1992, Volume: 15 Suppl 1 Pt A

    Topics: Anesthetics; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; gamma-Aminobutyric Acid; Ion Channels; Male; Pentobarbital; Pregnanediones; Propofol; Rats; Rats, Inbred Strains

1992
The general anesthetic propofol enhances the function of gamma-aminobutyric acid-coupled chloride channel in the rat cerebral cortex.
    Journal of neurochemistry, 1990, Volume: 55, Issue:6

    Topics: Anesthetics; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chloride Channels; gamma-Aminobutyric Acid; Male; Membrane Proteins; Pentobarbital; Picrotoxin; Pregnanediones; Propofol; Rats; Rats, Inbred Strains

1990
Lysosomal mutations increase susceptibility to anaesthetics.
    Experientia, 1989, Dec-01, Volume: 45, Issue:11-12

    Topics: Anesthesia; Anesthetics; Animals; Ethanol; Female; Homozygote; Lysosomes; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mutation; Pentobarbital; Pigmentation; Pregnanediones; Time Factors

1989
Analysis of cardiovascular responses evoked following changes in peripheral chemoreceptor activity in the rat.
    The Journal of physiology, 1987, Volume: 394

    Topics: Anesthesia, Intravenous; Anesthetics; Animals; Blood Pressure; Carotid Body; Dopamine; Female; Femoral Artery; Heart Rate; Male; Nitrogen; Oxygen; Pentobarbital; Pregnanediones; Rats; Renal Artery; Respiration; Vagotomy

1987
Cardiac performance of isolated beating hearts obtained from rats anesthetized by three different agents.
    Laboratory animal science, 1985, Volume: 35, Issue:2

    Topics: Anesthesia; Animals; Coronary Circulation; Ether; Ethyl Ethers; Heart; Heart Rate; Pentobarbital; Pregnanediones; Rats

1985
Modulation of the GABA receptor complex by a steroid anaesthetic.
    Brain research, 1984, Dec-10, Volume: 323, Issue:2

    Topics: Anesthetics; Animals; In Vitro Techniques; Male; Medulla Oblongata; Muscimol; Pentobarbital; Pregnanediones; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, GABA-A; Receptors, Muscarinic

1984
Effects of injectable anaesthetics on responses to L-glutamate and on spontaneous synaptic activity in lamprey reticulo-spinal neurones.
    British journal of pharmacology, 1984, Volume: 82, Issue:3

    Topics: Anesthetics; Animals; Brain Stem; Fishes; Glutamates; Glutamic Acid; Imidazoles; In Vitro Techniques; Iontophoresis; Ketamine; Lampreys; Medulla Oblongata; Membrane Potentials; Neurons; Pentobarbital; Pregnanediones; Reticular Formation; Synapses; Trigeminal Nucleus, Spinal

1984
Effects of anesthesia on the spontaneous activity of the microvasculature.
    International journal of microcirculation, clinical and experimental, 1984, Volume: 3, Issue:1

    Topics: Anesthetics; Animals; Arteries; Chloralose; Cricetinae; Ether; Mesocricetus; Microcirculation; Pentobarbital; Pregnanediones; Urethane; Vasodilation; Vasomotor System; Veins; Venules

1984
Dissimilar influences of some injectable anaesthetics on the responses of reticulo-spinal neurones to inhibitory transmitters in the lamprey.
    British journal of pharmacology, 1982, Volume: 77, Issue:3

    Topics: Anesthetics; Animals; gamma-Aminobutyric Acid; Glycine; Ketamine; Lampreys; Medulla Oblongata; Neurons; Pentobarbital; Pregnanediones

1982
Pharmacological properties of fetal rat hippocampal GABAA receptors.
    Brain research. Developmental brain research, 1995, Apr-18, Volume: 85, Issue:2

    Topics: Anesthetics; Animals; Cells, Cultured; Drug Synergism; Embryo, Mammalian; Fetus; gamma-Aminobutyric Acid; Hippocampus; Patch-Clamp Techniques; Pentobarbital; Pregnanediones; Rats; Receptors, GABA-A

1995
Pharmacology of GABA receptor Cl- channels in rat retinal bipolar cells.
    Nature, 1993, Jan-14, Volume: 361, Issue:6408

    Topics: Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Chloride Channels; Flunitrazepam; gamma-Aminobutyric Acid; Ion Channels; Membrane Potentials; Membrane Proteins; Neurons; Pentobarbital; Photoreceptor Cells; Picrotoxin; Pregnanediones; Rats; Receptors, GABA-A; Sesterterpenes; Strychnine

1993
Different subunit requirements for volatile and nonvolatile anesthetics at gamma-aminobutyric acid type A receptors.
    Molecular pharmacology, 1995, Volume: 47, Issue:2

    Topics: Anesthetics; Binding Sites; Cell Line; Flunitrazepam; Halothane; Humans; Isoflurane; Pentobarbital; Pregnanediones; Receptors, GABA-A

1995
Effects of propofol, pentobarbital and alphaxalone on t-[35S]butylbicyclophosphorothionate binding in rat cerebral cortex.
    European journal of pharmacology, 1994, Apr-15, Volume: 267, Issue:2

    Topics: Anesthetics; Animals; Bicuculline; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chloride Channels; Diazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channel Gating; Male; Membranes; Pentobarbital; Pregnanediones; Propofol; Rats; Rats, Sprague-Dawley; Sulfur Radioisotopes

1994
A comparison of propofol with other injectable anaesthetics in a rat model for measuring cardiovascular parameters.
    Laboratory animals, 1993, Volume: 27, Issue:3

    Topics: Anesthesia, Intravenous; Anesthetics; Animals; Blood Pressure; Butyrophenones; Female; Fentanyl; Heart Rate; Male; Midazolam; Pentobarbital; Pregnanediones; Propofol; Rats; Respiration; Thiopental

1993
A new highly sensitive procedure--a prerequisite to evaluate the density of GABAA receptors and to study their allosteric properties in distinct areas of rat brain.
    Biological chemistry Hoppe-Seyler, 1993, Volume: 374, Issue:1

    Topics: Allosteric Regulation; Animals; Binding Sites; Brain; Cerebellum; Desoxycorticosterone; Female; Frontal Lobe; Humans; Hydrogen-Ion Concentration; Muscimol; Pentobarbital; Pregnanediones; Pregnanolone; Progesterone; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A

1993
The influence of the gamma 2L subunit on the modulation of responses to GABAA receptor activation.
    British journal of pharmacology, 1993, Volume: 108, Issue:3

    Topics: Anesthetics; Animals; Fibroblasts; Flunitrazepam; gamma-Aminobutyric Acid; L Cells; Mice; Pentobarbital; Pregnanediones; Receptors, GABA-A; Recombinant Proteins; Transfection

1993
Characterization of the gamma-aminobutyric acidA receptor-channel complex composed of alpha 1 beta 2 and alpha 1 beta 3 subunits from rat brain.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 265, Issue:2

    Topics: Animals; Brain; Chlorides; CHO Cells; Cricetinae; Diazepam; gamma-Aminobutyric Acid; Membrane Potentials; Pentobarbital; Pregnanediones; Rats; Receptors, GABA-A; Transfection

1993
Biochemical evaluations of the effects of loreclezole and propofol on the GABAA receptor in rat brain.
    Biochemical pharmacology, 1996, Jun-14, Volume: 51, Issue:11

    Topics: Anesthetics; Animals; Anticonvulsants; Brain; Bridged Bicyclo Compounds, Heterocyclic; Diazepam; Flunitrazepam; GABA Modulators; gamma-Aminobutyric Acid; Hypnotics and Sedatives; In Vitro Techniques; Male; Muscimol; Pentobarbital; Pregnanediones; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sulfur Radioisotopes; Triazoles; Tritium

1996
Preemptive analgesic effects of steroid anesthesia with alphaxalone in the rat formalin test. Evidence for differential GABA(A) Receptor modulation in persistent nociception.
    Anesthesiology, 1996, Volume: 84, Issue:3

    Topics: Analgesics; Anesthetics; Animals; GABA Modulators; Male; Pentobarbital; Pregnanediones; Propofol; Rats; Receptors, GABA-A

1996
Bicuculline and gabazine are allosteric inhibitors of channel opening of the GABAA receptor.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Jan-15, Volume: 17, Issue:2

    Topics: Allosteric Regulation; Allosteric Site; Amino Acid Sequence; Animals; Bicuculline; Binding Sites; Binding, Competitive; Cell Line; Coturnix; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Ion Channel Gating; Ion Transport; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Pentobarbital; Point Mutation; Pregnanediones; Pregnanolone; Protein Binding; Pyridazines; Receptors, GABA-A; Structure-Activity Relationship

1997
GABAA receptor pharmacology and subtype mRNA expression in human neuronal NT2-N cells.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Jul-01, Volume: 18, Issue:13

    Topics: Anticonvulsants; Bicuculline; Carbolines; Convulsants; Diazepam; Diuretics; DNA Primers; Furosemide; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Lanthanum; Neurons; Patch-Clamp Techniques; Pentobarbital; Phenobarbital; Picrotoxin; Polymerase Chain Reaction; Pregnanediones; Pregnenolone; Pyridines; Receptors, GABA-A; RNA, Messenger; Teratocarcinoma; Triazoles; Tumor Cells, Cultured; Zinc; Zolpidem

1998
Absence seizures decrease steroid modulation of t-[35S]butylbicyclophosphorothionate binding in thalamic relay nuclei.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 287, Issue:2

    Topics: Action Potentials; Animals; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Desoxycorticosterone; Epilepsy, Absence; gamma-Aminobutyric Acid; Hydroxybutyrates; Male; Pentobarbital; Pregnanediones; Rats; Rats, Sprague-Dawley; Sulfur Radioisotopes; Thalamic Nuclei

1998
Pre- versus postinjury effects of intravenous GABAergic anesthetics on formalin-induced Fos immunoreactivity in the rat spinal cord.
    Anesthesia and analgesia, 1999, Volume: 88, Issue:2

    Topics: Adjuvants, Anesthesia; Analgesics; Analysis of Variance; Anesthetics; Anesthetics, Intravenous; Animals; Cell Nucleus; Coloring Agents; Cytoplasm; Disease Models, Animal; Fixatives; Formaldehyde; GABA Modulators; Immunoenzyme Techniques; Injections, Subcutaneous; Lumbar Vertebrae; Male; Pentobarbital; Pregnanediones; Propofol; Proto-Oncogene Proteins c-fos; Rats; Rats, Long-Evans; Spinal Cord

1999
GABA-Induced Cl- current in cultured embryonic human dorsal root ganglion neurons.
    Journal of neurophysiology, 1999, Volume: 82, Issue:1

    Topics: Adult; Baclofen; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Chloride Channels; Convulsants; Crotonates; Embryo, Mammalian; gamma-Aminobutyric Acid; Ganglia, Spinal; Glycine; Humans; Membrane Potentials; Neurons; Patch-Clamp Techniques; Pentobarbital; Potassium Channels; Pregnanediones; Receptors, GABA-A; Taurine

1999
Activation of rat locus coeruleus neuron GABA(A) receptors by propofol and its potentiation by pentobarbital or alphaxalone.
    European journal of pharmacology, 1999, Dec-15, Volume: 386, Issue:2-3

    Topics: Anesthetics; Anesthetics, Intravenous; Animals; Baclofen; Barium Compounds; Bicuculline; Chlorides; Diazepam; Drug Synergism; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Ionophores; Locus Coeruleus; Male; Neurons; Pentobarbital; Picrotoxin; Pregnanediones; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Zinc Compounds

1999
A single glycine residue at the entrance to the first membrane-spanning domain of the gamma-aminobutyric acid type A receptor beta(2) subunit affects allosteric sensitivity to GABA and anesthetics.
    Molecular pharmacology, 2000, Volume: 57, Issue:3

    Topics: Allosteric Regulation; Amino Acid Sequence; Anesthetics; Animals; Cells, Cultured; Chloride Channels; Electrophysiology; Etomidate; GABA Modulators; gamma-Aminobutyric Acid; Glycine; Ligands; Molecular Sequence Data; Mutagenesis, Site-Directed; Pentobarbital; Pregnanediones; Propofol; Protein Conformation; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Sequence Homology, Amino Acid; Spodoptera

2000
alpha4beta3delta GABA(A) receptors characterized by fluorescence resonance energy transfer-derived measurements of membrane potential.
    The Journal of biological chemistry, 2001, Oct-19, Volume: 276, Issue:42

    Topics: Animals; Benzodiazepines; Cell Line; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Humans; Membrane Potentials; Mice; Models, Biological; Muscimol; Pentobarbital; Pregnanediones; Pregnanolone; Protein Binding; Protein Conformation; Receptors, GABA-A; Spectrometry, Fluorescence; Time Factors; Transfection

2001
A single M1 residue in the beta2 subunit alters channel gating of GABAA receptor in anesthetic modulation and direct activation.
    The Journal of biological chemistry, 2003, Oct-31, Volume: 278, Issue:44

    Topics: Adjuvants, Anesthesia; Allosteric Site; Amino Acid Sequence; Anesthetics; Anesthetics, Intravenous; Animals; Cloning, Molecular; DNA Mutational Analysis; Dose-Response Relationship, Drug; Etomidate; Kinetics; Ligands; Models, Biological; Molecular Sequence Data; Mutagenesis; Mutation; Oocytes; Patch-Clamp Techniques; Pentobarbital; Point Mutation; Pregnanediones; Propofol; Protein Structure, Tertiary; Rats; Receptors, GABA-A; Recombinant Proteins; RNA, Messenger; Xenopus

2003
Ethyl 2-(4-bromophenyl)-1-(2,4-dichlorophenyl)-1H-4-imidazolecarboxylate is a novel positive modulator of GABAA receptors.
    European journal of pharmacology, 2005, Jun-15, Volume: 516, Issue:3

    Topics: Animals; Binding, Competitive; Cell Membrane; Cerebral Cortex; Diazepam; Dose-Response Relationship, Drug; Etomidate; Female; Flunitrazepam; GABA Modulators; gamma-Aminobutyric Acid; Glycine; Humans; Hydrocarbons, Halogenated; Imidazoles; Male; Membrane Potentials; Oocytes; Pentobarbital; Pregnanediones; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Glycine; Receptors, Serotonin, 5-HT3; Serotonin; Tritium; Xenopus laevis

2005
Influence of external and intracellular pH on propofol-induced responses in rat locus coeruleus neurons.
    European journal of pharmacology, 2006, Sep-18, Volume: 545, Issue:2-3

    Topics: Acidosis; Animals; Hydrogen-Ion Concentration; In Vitro Techniques; Locus Coeruleus; Male; Pentobarbital; Pregnanediones; Propofol; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-A

2006
Changes in relative potency among positive GABA(A) receptor modulators upon discontinuation of chronic benzodiazepine treatment in rhesus monkeys.
    Psychopharmacology, 2007, Volume: 192, Issue:1

    Topics: Animals; Behavior, Animal; Benzodiazepines; Diazepam; Discrimination Learning; Dose-Response Relationship, Drug; Female; Flumazenil; GABA Modulators; Lorazepam; Macaca mulatta; Male; Midazolam; Pentobarbital; Pregnanediones; Pregnanolone; Receptors, GABA-A; Substance Withdrawal Syndrome

2007
The effect of alphaxalone-alphadolone, propofol, and pentobarbitone anaesthesia on the β-endorphin and ACTH response to haemorrhage in the pig.
    Canadian journal of physiology and pharmacology, 2011, Volume: 89, Issue:7

    Topics: Adrenocorticotropic Hormone; Anesthesia; Anesthetics; Animals; beta-Endorphin; Blood Pressure; Heart Rate; Hemorrhage; Hypovolemia; Pentobarbital; Pregnanediones; Propofol; Swine

2011
The benzodiazepine diazepam potentiates responses of α1β2γ2L γ-aminobutyric acid type A receptors activated by either γ-aminobutyric acid or allosteric agonists.
    Anesthesiology, 2013, Volume: 118, Issue:6

    Topics: Anesthetics; Animals; Binding Sites; Diazepam; Drug Synergism; Etomidate; GABA Modulators; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Patch-Clamp Techniques; Pentobarbital; Pregnanediones; Rats; Receptors, GABA-A

2013
Synaptic-type α1β2γ2L GABAA receptors produce large persistent currents in the presence of ambient GABA and anesthetic drugs.
    Molecular pharmacology, 2015, Volume: 87, Issue:5

    Topics: Anesthetics; Animals; Cell Line; Chromosome Pairing; Etomidate; gamma-Aminobutyric Acid; HEK293 Cells; Humans; Pentobarbital; Pregnanediones; Propofol; Rats; Receptors, GABA-A

2015
GABA Type A Receptor Activation in the Allosteric Coagonist Model Framework: Relationship between EC
    Molecular pharmacology, 2018, Volume: 93, Issue:2

    Topics: Allosteric Regulation; Anesthetics; Animals; Binding Sites; Dose-Response Relationship, Drug; Drug Interactions; GABA Agonists; gamma-Aminobutyric Acid; Models, Biological; Models, Theoretical; Mutation; Oocytes; Patch-Clamp Techniques; Pentobarbital; Pregnanediones; Propofol; Receptors, GABA-A; Xenopus laevis

2018