Compounds > pentetic acid

pentetic acid and yttrium radioisotopes

pentetic acid has been researched along with yttrium radioisotopes in 79 studies

Research

Studies (79)

TimeframeStudies, this research(%)All Research%
pre-19905 (6.33)18.7374
1990's40 (50.63)18.2507
2000's23 (29.11)29.6817
2010's10 (12.66)24.3611
2020's1 (1.27)2.80

Authors

AuthorsStudies
Hnatowich, DJ; Virzi, F; Wu, C1
Goldenberg, DM; Motta-Hennessy, C; Sharkey, RM1
Beeley, NR; Boyce, RA; Chaplin, L; Cox, JP; Craig, AS; Harrison, A; Jankowski, KJ; Parker, D; Sansom, JM; Walker, CA1
Bosslet, K; Bruynck, A; Hermentin, P; Kuhlmann, L; Magerstaedt, M; Schwarz, A; Sedlacek, HH; Seemann, G; Steinstraesser, A1
Brechbiel, MW; Fand, I; Gansow, OA; Goldenberg, DM; Griffiths, GL; Jones, AL; Motta-Hennessy, C; Sharkey, RM1
Byrd, BL; Crook, JE; Holloway, EC; Lee, YC; Steplewski, Z; Sun, TT; Washburn, LC1
Fowler, JF; Hsieh, JT; Kinsella, TJ; Kubsad, SS; Mehta, MP; Verma, AK1
Bosslet, K; Hermentin, P; Kuhlmann, L; Sedlacek, HH; Seemann, G; Steinstraesser, A1
Mather, SJ; Tolley, DM; White, GW1
Beaney, RP; Keeling, AA; Vaughan, AT1
Epenetos, AA; Hnatowich, DJ; Rowlinson, G; Snook, D; Stewart, S1
Chinol, M; Doherty, PW; Gionet, M; Griffin, T; Hnatowich, DJ; Hunter, R; Kase, KR; Siebecker, DA1
Doherty, PW; Hnatowich, DJ; Virzi, F1
Butchko, G; Dufton, C; Glenn, SD; Johnson, T; Kasliwal, R; Lear, J; Matthes, S; Schrier, DM; Stemmer, SM; Taffs, S1
Kalaga, R; Kaveri, S; Li, L; Paul, S1
Epenetos, AA; Gooden, CS; Kosmas, C; Maraveyas, A; Snook, D1
Beresford, BA; Häfeli, UO; Humm, JL; Macklis, RM; Sweeney, SM1
Brechbiel, MW; Camera, L; Gansow, OA; Garmestani, K; Kinuya, S; McMurry, TJ; Pai, LH; Paik, CH; Pastan, I; Wu, C2
Ceriani, R; DeNardo, SJ; Furmanski, P; Glenn, SD; Kramer, EL; Kroger, L; Liebes, L; Noz, ME1
DeNardo, GL; DeNardo, SJ; Fand, I; Kroger, LA; Kukis, DL; Meares, CF; Miers, LA; Renn, O; Salako, Q; Shen, S1
Blum, JE; Leichner, PK; Quadri, SM; Shao, Y; Vriesendorp, HM; Williams, JR1
Blum, JE; Quadri, SM; Shao, Y; Vriesendorp, HM; Williams, JR1
Bartolazzi, A; Bonino, C; Camagna, M; DeMonte, LB; Lombardi, A; Natali, PG; Paganelli, G; Parisi, A; Tarditi, L; Vassarotto, C1
Hnatowich, DJ; Mardirossian, G; Wu, C1
Albert, R; Briner, U; Bruns, C; Mäcke, H; Ruser, G; Smith-Jones, P; Stolz, B; Tolcsvai, L; Weckbecker, G1
Chinol, M; Fazio, F; Meares, C; Paganelli, G; Sudati, F1
Bakker, WH; Béhé, M; Bernard, BF; Breeman, WA; de Jong, M; Jermann, E; Krenning, EP; Mäcke, HR; Powell, P; van der Pluijm, ME; Visser, TJ1
Behe, M; Bucher, HC; Goetze, M; Heppeler, A; Jermann, E; Maecke, HR; Mueller-Brand, J; Otte, A; Roser, HW1
Ceriani, RL; DeNardo, GL; DeNardo, SJ; Glenn, SD; Kramer, EL; Noz, M; O'Donnell, RT; Richman, CM; Salako, QA; Shen, S1
Albert, R; Bruns, C; Knecht, H; Smith-Jones, PM; Stolz, B1
Bakker, WH; Bernard, BF; Breeman, WA; de Jong, M; Krenning, EP; Mäcke, H; Rolleman, EJ; Visser, TJ1
Bakker, WH; Béhé, M; Bernard, BF; Breeman, WA; De Jong, M; Hofland, LJ; Krenning, EP; Mäcke, HR; Schmidt, M; Srinivasan, A; Visser, TJ1
Brechbiel, MW; Carrasquillo, JA; Drumm, D; Gansow, OA; Kobayashi, H; Paik, CH; Pastan, I; Sun, BF; Wu, C; Yoo, TM1
Albert, R; Briner, U; Bruns, C; Mäcke, HR; Ruser, G; Smith-Jones, PM; Stolz, B1
Bakker, WH; Bernard, BF; De Bruin, E; De Jong, M; Krenning, EP; Mäcke, HR; Van Gameren, A; Visser, TJ1
Blank, EW; Ceriani, RL; Furmanski, P; Kramer, EL; Liebes, L; Melamed, J; Noz, ME; Peterson, JA; Wasserheit, C; Zabalegui, A1
Brechbiel, MW; Deal, KA; Gansow, OA; McMurry, TJ; Mirzadeh, S; Pippin, CG; Wu, C1
Chinol, M; Cremonesi, M; Ferrari, M; Grana, C; Paganelli, G; Prisco, G; Robertson, C; Stabin, MG; Tosi, G1
Brechbiel, MW; Carrasquillo, JA; Gansow, OA; Le, N; Nelson, DL; Paik, CH; Perentesis, P; Raubitschek, A; Reynolds, JC; Rotman, M; Top, LE; Waldmann, TA; White, JD1
Brechbiel, M; Kennel, SJ; Mirzadeh, S; Stabin, M; Yoriyaz, H1
Doroshow, JH; Forman, S; Liu, A; Odom-Maryon, T; Raubitschek, AA; Shively, JE; Somlo, G; Wilczynski, S; Williams, LE; Wong, JY; Wu, AM; Yamauchi, D; Yazaki, P1
Emmanouilides, C; Gordon, LI; Grillo-López, AJ; Gutheil, J; Janakiraman, N; Raubitschek, A; Schilder, RJ; Silverman, DH; Spies, S; White, CA; Wiseman, GA; Witzig, TE1
Endo, K; Inoue, T; Murata, H; Oriuchi, N; Sasaki, Y; Tanada, S; Watanabe, N1
Brechbiel, MW; Colcher, D; Gansow, OA; Milenic, DE; Mirzadeh, S; Pippin, CG; Roselli, M; Schlom, J1
de Jong, M; Krenning, EP; Kwekkeboom, D1
Chu, DZ; Doroshow, JH; Liu, A; Raubitschek, AA; Shively, JE; Wilczynski, S; Williams, LE; Wu, AM; Yamauchi, DM1
Blank, E; Ceriani, R; Furmanski, P; Hochster, H; Kramer, E; Liebes, L; Ng, B; Wasserheit, C1
Bakker, WH; Breeman, WA; De Jong, M; Jamar, F; Krenning, EP; Kvols, LK; Kwekkeboom, DJ; Pauwels, S; Smith, C; Valkema, R1
Andreae, F; Angelberger, P; Burggasser, G; Dudczak, R; Füger, B; Kurtaran, A; Leimer, M; Li, SR; Novotny, C; Pangerl, T; Patri, P; Raderer, M; Traub, T; Virgolini, I1
Das, T; Mukherjee, A; Pandey, U; Pillai, MR; Sarma, HD; Venkatesh, M1
Fisher, DR; Goldenberg, DM; Govindan, SV; Griffiths, GL; Sharkey, RM1
Angerstein, C; Becker, W; Béhé, M; Behr, TM; Gotthardt, M1
Brechbiel, MW; Burns, LJ; Dusenbery, KE; Elson, M; Jaszcz, WB; Kersey, JH; Kuroki, DW; Panoskaltsis-Mortari, A; Ramsay, NK; Skubitz, KM; Vallera, DA; Wagner, JE1
Blend, MJ; Brechbiel, MW; Stastny, JJ; Swanson, SM1
Boerman, OC; Brouwers, AH; Corstens, FH; Frielink, C; Oosterwijk, E; Oyen, WJ; van Eerd, JE1
Bernard, BF; Breeman, WA; De Blois, E; De Jong, M; De Jong, MT; Krenning, EP1
Adams, GP; Brechbiel, MW; Dadachova, E; Horak, EM; Klein-Szanto, AJ; Marks, JD; Shaller, CC; Simmons, HH; Tesfaye, A; Weiner, LM1
Alicke, B; Biroc, S; Bringmann, P; Cobb, RR; Dinter, H; Halks-Miller, M; Harkins, R; Hudson, D; Klocker, H; Kretschmer, PJ; Larsen, B; Lewis, JS; Lin, R; Newton, A; Parkes, D; Parry, G; Parry, R; Roth, G; Schneider, D; Toy, P; Xuan, JA; Zhu, Y1
de Jong, M; Esser, JP; Krenning, EP; Kwekkeboom, DJ; Teunissen, JJ; Valkema, R1
Brechbiel, MW; Burgess, AW; Hall, C; Johns, TG; Kelly, MP; Lee, FT; Mountain, AJ; Nice, EC; Rigopoulos, A; Scott, AM; Smyth, FE1
Busby, E; Carey, D; Forero, A; Grizzle, WE; Khazaeli, MB; LoBuglio, AF; Meredith, RF; Robert, F; Shen, S1
Biddlecombe, GB; Boswell, CA; Brechbiel, MW; Clifford, T; Lewis, JS1
Fu, YB; Li, GP; Meng, FY1
An, R; Biersack, HJ; Gao, ZR; Zhang, YX1
Baidoo, K; Boswell, CA; Brechbiel, MW; Choyke, PL; Gunn, AJ; Milenic, DE; Xu, H1
Bergmann, R; Johannsen, B; Noll, B; Pietzsch, HJ; Pietzsch, J; Schiller, E; Sterger, A; Wunderlich, G1
Alicke, B; Heitner, T; Lewis, JS; Light, DR; McLean, K; Parry, G; Parry, R; Satozawa, N; Schneider, DW; Yoo, J1
Baidoo, KE; Brechbiel, MW; Garmestani, K; Milenic, DE; Nayak, TK; Regino, CA; Szajek, LP; Wong, KJ1
Baidoo, KE; Brechbiel, MW; Garmestani, K; Milenic, DE; Nayak, TK3
Baumann, M; Cordes, N; Dittfeld, C; Heldt, JM; Ingargiola, M; Kotzerke, J; Kunz-Schughart, LA; Runge, R; Steinbach, J; Zenker, M1
Baumann, M; Bergmann, R; Brüchner, K; Koi, L; Krause, M; Pietzsch, HJ; Pietzsch, J; Steinbach, J; Zips, D1
Ballard, B; Cutler, CS; Dadachova, E; Francesconi, LC; Jiang, Z; Miller, WH; Revskaya, E; Sisay, N; Thompson, S1
Baumann, M; Cordes, N; Eke, I; Förster, C; Freudenberg, R; Heldt, JM; Ingargiola, M; Kotzerke, J; Kunz-Schughart, LA; Pietzsch, HJ; Runge, R; Steinbach, J1
Chakraborty, S; Chakravarty, R; Dash, A1
Adam, MJ; Carlin, SD; Carnazza, KE; Edwards, KJ; Lewis, JS; Orvig, C; Price, EW; Zeglis, BM1
Aleksandar, V; Dragana, S; Drina, J; Magdalena, R; Marija, M; Sanja, VĐ; Zorana, M1

Reviews

6 review(s) available for pentetic acid and yttrium radioisotopes

ArticleYear
Preparation and use of DTPA-coupled antitumor antibodies radiolabeled with yttrium-90.
    Targeted diagnosis and therapy, 1988, Volume: 1

    Topics: Animals; Antibodies, Monoclonal; Drug Carriers; Humans; Mice; Mice, Nude; Neoplasms; Pentetic Acid; Yttrium Radioisotopes

1988
Radioimmunotherapy of relapsed non-Hodgkin's lymphoma with zevalin, a 90Y-labeled anti-CD20 monoclonal antibody.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:10 Suppl

    Topics: Antibodies, Monoclonal; Antigens, CD20; Humans; Lymphoma, Non-Hodgkin; Pentetic Acid; Radioimmunotherapy; Recurrence; Yttrium Radioisotopes

1999
Peptide receptor imaging and therapy.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2000, Volume: 41, Issue:10

    Topics: Humans; Indium Radioisotopes; Neoplasms; Neuroendocrine Tumors; Octreotide; Oligopeptides; Pentetic Acid; Radiopharmaceuticals; Receptors, Somatostatin; Tomography, Emission-Computed, Single-Photon; Yttrium Radioisotopes

2000
Somatostatin receptor-targeted radionuclide therapy of tumors: preclinical and clinical findings.
    Seminars in nuclear medicine, 2002, Volume: 32, Issue:2

    Topics: Animals; Humans; Indium Radioisotopes; Liver Neoplasms; Neuroendocrine Tumors; Octreotide; Organometallic Compounds; Pancreatic Neoplasms; Pentetic Acid; Radiopharmaceuticals; Rats; Receptors, Somatostatin; Tumor Cells, Cultured; Yttrium Radioisotopes

2002
Experience with indium-111 and yttrium-90-labeled somatostatin analogs.
    Current pharmaceutical design, 2002, Volume: 8, Issue:20

    Topics: Heterocyclic Compounds; Humans; Indium Radioisotopes; Neoplasms; Octreotide; Pentetic Acid; Peptides, Cyclic; Radionuclide Imaging; Radiopharmaceuticals; Receptors, Somatostatin; Somatostatin; Yttrium Radioisotopes

2002
Endocrine tumours of the gastrointestinal tract. Peptide receptor radionuclide therapy.
    Best practice & research. Clinical gastroenterology, 2005, Volume: 19, Issue:4

    Topics: Animals; Carcinoma, Neuroendocrine; Gastrointestinal Neoplasms; Humans; Indium Radioisotopes; Lutetium; Octreotide; Organometallic Compounds; Pancreatic Neoplasms; Patient Selection; Pentetic Acid; Peptides, Cyclic; Quality of Life; Radionuclide Imaging; Radiopharmaceuticals; Receptors, Peptide; Receptors, Somatostatin; Somatostatin; Treatment Outcome; Yttrium Radioisotopes

2005

Trials

10 trial(s) available for pentetic acid and yttrium radioisotopes

ArticleYear
High-dose 90Y Mx-diethylenetriaminepentaacetic acid (DTPA)-BrE-3 and autologous hematopoietic stem cell support (AHSCS) for the treatment of advanced breast cancer: a phase I trial.
    Cancer research, 1995, Dec-01, Volume: 55, Issue:23 Suppl

    Topics: Adult; Aged; Animals; Antibodies, Monoclonal; Breast Neoplasms; Combined Modality Therapy; Female; Hematopoietic Stem Cell Transplantation; Humans; Mice; Middle Aged; Pentetic Acid; Radioimmunotherapy; Yttrium Radioisotopes

1995
Anti-chelate antibodies after intraperitoneal yttrium-90-labeled monoclonal antibody immunoconjugates for ovarian cancer therapy.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1995, Volume: 36, Issue:5

    Topics: Antibodies; Blotting, Western; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunoglobulin G; Immunoglobulin M; Ovarian Neoplasms; Pentetic Acid; Radioimmunotherapy; Yttrium Radioisotopes

1995
Radioimmunolocalization of breast cancer using BrE-3 monoclonal antibody.
    Advances in experimental medicine and biology, 1994, Volume: 353

    Topics: Animals; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal; Antibody Specificity; Biomarkers, Tumor; Breast Neoplasms; Carcinoembryonic Antigen; Female; Humans; Immunoconjugates; Indium Radioisotopes; Membrane Glycoproteins; Mice; Middle Aged; Mucin-1; Mucins; Pentetic Acid; Radioimmunodetection; Yttrium Radioisotopes

1994
Radioimmunotherapy for breast cancer using indium-111/yttrium-90 BrE-3: results of a phase I clinical trial.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1997, Volume: 38, Issue:8

    Topics: Breast Neoplasms; Chelating Agents; Female; Humans; Indium Radioisotopes; Middle Aged; Pentetic Acid; Radioimmunotherapy; Radiotherapy Dosage; Yttrium Radioisotopes

1997
Three-step radioimmunotherapy with yttrium-90 biotin: dosimetry and pharmacokinetics in cancer patients.
    European journal of nuclear medicine, 1999, Volume: 26, Issue:2

    Topics: Antibodies, Monoclonal; Avidin; Biotinylation; Bone Marrow; Chelating Agents; Heterocyclic Compounds, 1-Ring; Humans; Kidney; Liver; Models, Biological; Neoplasms; Pentetic Acid; Radioimmunotherapy; Radiopharmaceuticals; Radiotherapy Dosage; Streptavidin; Tomography, Emission-Computed; Urinary Bladder; Whole-Body Counting; Yttrium Radioisotopes

1999
Initial clinical experience evaluating Yttrium-90-chimeric T84.66 anticarcinoembryonic antigen antibody and autologous hematopoietic stem cell support in patients with carcinoembryonic antigen-producing metastatic breast cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:10 Suppl

    Topics: Animals; Breast Neoplasms; Carcinoembryonic Antigen; Combined Modality Therapy; Female; Hematopoietic Stem Cell Transplantation; Humans; Immunoglobulin G; Mice; Pentetic Acid; Radioimmunoassay; Recombinant Fusion Proteins; Transplantation, Autologous; Yttrium Radioisotopes

1999
A phase I radioimmunotherapy trial evaluating 90yttrium-labeled anti-carcinoembryonic antigen (CEA) chimeric T84.66 in patients with metastatic CEA-producing malignancies.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:10

    Topics: Animals; Antibodies, Monoclonal; Bone Marrow; Carcinoembryonic Antigen; Colorectal Neoplasms; Humans; Immunoglobulin G; Liver; Lung Neoplasms; Mice; Pentetic Acid; Radioimmunotherapy; Radioisotopes; Recombinant Fusion Proteins; Thyroid Neoplasms; Time Factors; Yttrium Radioisotopes

2000
Improved kinetic stability of DTPA- dGlu as compared with conventional monofunctional DTPA in chelating indium and yttrium: preclinical and initial clinical evaluation of radiometal labelled minigastrin derivatives.
    European journal of nuclear medicine and molecular imaging, 2003, Volume: 30, Issue:8

    Topics: Animals; Carcinoma, Medullary; Cell Line, Tumor; Chelating Agents; Drug Evaluation, Preclinical; Drug Stability; Female; Gastrins; Humans; Indium Radioisotopes; Kinetics; Male; Metabolic Clearance Rate; Mice; Mice, Nude; Organ Specificity; Pentetic Acid; Radionuclide Imaging; Radiopharmaceuticals; Staining and Labeling; Thyroid Neoplasms; Tissue Distribution; Whole-Body Counting; Yttrium Radioisotopes

2003
Phase I study of 90Y-CC49 monoclonal antibody therapy in patients with advanced non-small cell lung cancer: effect of chelating agents and paclitaxel co-administration.
    Cancer biotherapy & radiopharmaceuticals, 2005, Volume: 20, Issue:5

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Neoplasm; Antigens, Neoplasm; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Chelating Agents; Clinical Trials as Topic; Disease Progression; Edetic Acid; Female; Glycoproteins; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Neutropenia; Paclitaxel; Pentetic Acid; Radioimmunotherapy; Radiometry; Thrombocytopenia; Treatment Outcome; Up-Regulation; Yttrium Radioisotopes

2005
[Targeted radionuclide therapy for patients with metastatic medullary thyroid carcinoma].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2006, Volume: 28, Issue:8

    Topics: 3-Iodobenzylguanidine; Adult; Aged; Antineoplastic Agents; Carcinoma, Medullary; Female; Follow-Up Studies; Humans; Indium Radioisotopes; Male; Middle Aged; Octreotide; Pentetic Acid; Positron-Emission Tomography; Remission Induction; Thyroid Gland; Thyroid Hormones; Thyroid Neoplasms; Treatment Outcome; Yttrium Radioisotopes

2006

Other Studies

63 other study(ies) available for pentetic acid and yttrium radioisotopes

ArticleYear
Investigations of N-linked macrocycles for 111In and 90Y labeling of proteins.
    International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology, 1992, Volume: 19, Issue:2

    Topics: Amines; Animals; Avidin; Biotin; Chelating Agents; Drug Stability; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Indium Radioisotopes; Mice; Pentetic Acid; Proteins; Tissue Distribution; Yttrium Radioisotopes

1992
Labeling of monoclonal antibody conjugates with 90Y.
    International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes, 1991, Volume: 42, Issue:5

    Topics: Antibodies, Monoclonal; Carcinoembryonic Antigen; Chelating Agents; Isotope Labeling; Pentetic Acid; Yttrium Radioisotopes

1991
The in vivo release of 90Y from cyclic and acyclic ligand-antibody conjugates.
    International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology, 1991, Volume: 18, Issue:5

    Topics: Animals; Antibodies, Monoclonal; Bone and Bones; Bone Marrow; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Immunoglobulin G; Isotope Labeling; Ligands; Male; Mice; Mice, Inbred Strains; Pentetic Acid; Yttrium Radioisotopes

1991
Generation of bispecific monoclonal antibodies for two phase radioimmunotherapy.
    British journal of cancer, 1991, Volume: 63, Issue:5

    Topics: Animals; Antibodies, Monoclonal; Colonic Neoplasms; Humans; Injections, Intravenous; Mice; Mice, Nude; Pancreatic Neoplasms; Pentetic Acid; Tumor Cells, Cultured; Yttrium Radioisotopes

1991
Selection of a DTPA chelate conjugate for monoclonal antibody targeting to a human colonic tumor in nude mice.
    International journal of cancer, 1990, Jul-15, Volume: 46, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Autoradiography; Carcinoembryonic Antigen; Chelating Agents; Colonic Neoplasms; Female; Immunotoxins; Indium Radioisotopes; Mice; Mice, Nude; Neoplasm Transplantation; Pentetic Acid; Tissue Distribution; Whole-Body Counting; Yttrium Radioisotopes

1990
Radioimmunotherapy of human colorectal carcinoma xenografts using 90Y-labeled monoclonal antibody CO17-1A prepared by two bifunctional chelate techniques.
    Cancer research, 1990, Aug-01, Volume: 50, Issue:15

    Topics: Amifostine; Animals; Antibodies, Monoclonal; Cell Division; Cell Line; Chelating Agents; Colorectal Neoplasms; Female; Hemoglobins; Humans; Immunotherapy; Mice; Mice, Nude; Neoplasm Transplantation; Pentetic Acid; Transplantation, Heterologous; Yttrium Radioisotopes

1990
90Y.B72.3 against pancreatic cancer: dosimetric and biological analysis.
    International journal of radiation oncology, biology, physics, 1990, Volume: 19, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Carcinoma; Female; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Pancreatic Neoplasms; Pentetic Acid; Radiotherapy Dosage; Tissue Distribution; Transplantation, Heterologous; Yttrium Radioisotopes

1990
Two-phase radioimmunotherapy using bispecific monoclonal antibodies (bs MAbs).
    Cancer treatment reviews, 1990, Volume: 17, Issue:2-3

    Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Carcinoembryonic Antigen; Humans; Mice; Neoplasms, Experimental; Pentetic Acid; Radiotherapy; Receptors, Drug; Yttrium Radioisotopes

1990
Labelling monoclonal antibodies with yttrium-90.
    European journal of nuclear medicine, 1989, Volume: 15, Issue:6

    Topics: Antibodies, Monoclonal; Drug Stability; Humans; Isotope Labeling; Pentetic Acid; Yttrium Radioisotopes

1989
Yttrium-90-EDTMP: a radiotherapeutic agent in the treatment of leukaemias.
    British journal of cancer, 1989, Volume: 60, Issue:1

    Topics: Animals; Bone and Bones; Leukemia, Experimental; Male; Mice; Mice, Inbred BALB C; Organometallic Compounds; Organophosphonates; Organophosphorus Compounds; Pentetic Acid; Tissue Distribution; Yttrium Radioisotopes

1989
Patient biodistribution of intraperitoneally administered yttrium-90-labeled antibody.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1988, Volume: 29, Issue:8

    Topics: Animals; Antibodies, Monoclonal; Female; Humans; Immunization; Injections, Intraperitoneal; Mice; Mice, Inbred BALB C; Ovarian Neoplasms; Ovary; Pentetic Acid; Radiation Dosage; Radionuclide Imaging; Reoperation; Tissue Distribution; Yttrium Radioisotopes

1988
DTPA-coupled antibodies labeled with yttrium-90.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1985, Volume: 26, Issue:5

    Topics: Animals; Humans; Immunoglobulin Fab Fragments; Immunoglobulin G; Immunotherapy; Indium; Isotope Labeling; Male; Mice; Pentetic Acid; Radioisotopes; Time Factors; Tissue Distribution; Yttrium Radioisotopes

1985
Methods of measuring thyroglobulin and peptide-methylcoumarinamide hydrolysis by autoantibodies.
    Methods in molecular biology (Clifton, N.J.), 1995, Volume: 51

    Topics: Autoantibodies; Catalysis; Chromatography, Affinity; Chromatography, Gel; Humans; Hydrolysis; Indicators and Reagents; Indium Radioisotopes; Iodine Radioisotopes; Isotope Labeling; Pentetic Acid; Radioisotope Dilution Technique; Thyroglobulin; Thyroiditis, Autoimmune; Yttrium Radioisotopes

1995
Effective targeting of magnetic radioactive 90Y-microspheres to tumor cells by an externally applied magnetic field. Preliminary in vitro and in vivo results.
    Nuclear medicine and biology, 1995, Volume: 22, Issue:2

    Topics: Animals; Cell Line; Cell Survival; Culture Techniques; Dose-Response Relationship, Radiation; Female; Humans; Lactates; Lactic Acid; Lymphoma; Magnetics; Mice; Mice, Inbred C57BL; Microspheres; Neuroblastoma; Pentetic Acid; Polyesters; Polymers; Radionuclide Imaging; Skin Neoplasms; Tissue Distribution; Tumor Cells, Cultured; Yttrium Radioisotopes

1995
Comparative biodistribution of indium- and yttrium-labeled B3 monoclonal antibody conjugated to either 2-(p-SCN-Bz)-6-methyl-DTPA (1B4M-DTPA) or 2-(p-SCN-Bz)-1,4,7,10-tetraazacyclododecane tetraacetic acid (2B-DOTA).
    European journal of nuclear medicine, 1994, Volume: 21, Issue:7

    Topics: Animals; Chelating Agents; Female; Heterocyclic Compounds; Indium Radioisotopes; Isothiocyanates; Mice; Mice, Nude; Pentetic Acid; Radioimmunotherapy; Tissue Distribution; Yttrium Radioisotopes

1994
Evaluation of the serum stability and in vivo biodistribution of CHX-DTPA and other ligands for yttrium labeling of monoclonal antibodies.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1994, Volume: 35, Issue:5

    Topics: Animals; Bone and Bones; Chelating Agents; Drug Stability; Female; Heterocyclic Compounds; Indium Radioisotopes; Isothiocyanates; Ligands; Mice; Mice, Nude; Pentetic Acid; Radioimmunotherapy; Tissue Distribution; Yttrium Radioisotopes

1994
Comparative toxicity studies of yttrium-90 MX-DTPA and 2-IT-BAD conjugated monoclonal antibody (BrE-3).
    Cancer, 1994, Feb-01, Volume: 73, Issue:3 Suppl

    Topics: Animals; Blood Cell Count; Blood Platelets; Body Weight; Bone Marrow; Chelating Agents; Female; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Mice; Mice, Inbred BALB C; Mucins; Pentetic Acid; Radioimmunotherapy; Radiotherapy Dosage; Yttrium Radioisotopes

1994
Preclinical evaluation of intravenously administered 111In- and 90Y-labeled B72.3 immunoconjugate (GYK-DTPA) in beagle dogs.
    Nuclear medicine and biology, 1993, Volume: 20, Issue:5

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Neoplasm; Dogs; Female; Humans; Indium Radioisotopes; Infusions, Intravenous; Male; Oligopeptides; Pentetic Acid; Yttrium Radioisotopes

1993
Fractionated intravenous administration of 90Y-labeled B72.3 GYK-DTPA immunoconjugate in beagle dogs.
    Nuclear medicine and biology, 1993, Volume: 20, Issue:5

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Neoplasm; Dogs; Female; Half-Life; Infusions, Intravenous; Male; Oligopeptides; Pentetic Acid; Yttrium Radioisotopes

1993
BIS-1: a novel bispecific monoclonal antibody for CEA-expressing carcinoma radioimmunoscintigraphy and radioimmunotherapy.
    The Year in immunology, 1993, Volume: 7

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Neoplasm; Antibody Specificity; Carcinoembryonic Antigen; Carcinoma; Genetic Vectors; Humans; Hybridomas; Indium Radioisotopes; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Pentetic Acid; Radioimmunodetection; Radioimmunotherapy; Recombinant Fusion Proteins; Yttrium Radioisotopes

1993
The stability in liver homogenates of indium-111 and yttrium-90 attached to antibody via two popular chelators.
    Nuclear medicine and biology, 1993, Volume: 20, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Chelating Agents; Chromatography, Ion Exchange; Chromatography, Thin Layer; In Vitro Techniques; Indium Radioisotopes; Liver; Male; Mice; Pentetic Acid; Radiometry; Yttrium Radioisotopes

1993
Somatostatin analogues for somatostatin-receptor-mediated radiotherapy of cancer.
    Digestion, 1996, Volume: 57 Suppl 1

    Topics: Animals; Chelating Agents; Hormone Antagonists; In Vitro Techniques; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Experimental; Octreotide; Pentetic Acid; Pituitary Gland; Rats; Receptors, Somatostatin; Somatostatin; Tissue Distribution; Yttrium Radioisotopes

1996
Biodistribution in tumour-bearing mice of two 90Y-labelled biotins using three-step tumour targeting.
    Nuclear medicine communications, 1997, Volume: 18, Issue:2

    Topics: Adenocarcinoma; Animals; Avidin; Beta Particles; Biotin; Bone and Bones; Colonic Neoplasms; Humans; Liver; Male; Mice; Mice, Nude; Pentetic Acid; Radioimmunotherapy; Time Factors; Tissue Distribution; Transplantation, Heterologous; Yttrium Radioisotopes

1997
Yttrium-90 and indium-111 labelling, receptor binding and biodistribution of [DOTA0,d-Phe1,Tyr3]octreotide, a promising somatostatin analogue for radionuclide therapy.
    European journal of nuclear medicine, 1997, Volume: 24, Issue:4

    Topics: Animals; Indium Radioisotopes; Male; Octreotide; Pentetic Acid; Radiopharmaceuticals; Rats; Rats, Inbred Lew; Rats, Wistar; Receptors, Somatostatin; Tissue Distribution; Yttrium Radioisotopes

1997
DOTATOC: a powerful new tool for receptor-mediated radionuclide therapy.
    European journal of nuclear medicine, 1997, Volume: 24, Issue:7

    Topics: Abdominal Neoplasms; Adult; Humans; Indium Radioisotopes; Male; Middle Aged; Neuroendocrine Tumors; Octreotide; Pentetic Acid; Radionuclide Imaging; Radiopharmaceuticals; Receptors, Somatostatin; Sensitivity and Specificity; Yttrium Radioisotopes

1997
Synthesis, biodistribution and renal handling of various chelate-somatostatin conjugates with metabolizable linking groups.
    Nuclear medicine and biology, 1997, Volume: 24, Issue:8

    Topics: Animals; Chelating Agents; Cross-Linking Reagents; Drug Stability; Enzyme Stability; Indium Radioisotopes; Kidney; Male; Pentetic Acid; Rats; Rats, Inbred Lew; Receptors, Somatostatin; Somatostatin; Tissue Distribution; Yttrium Radioisotopes

1997
D-lysine reduction of indium-111 octreotide and yttrium-90 octreotide renal uptake.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1997, Volume: 38, Issue:12

    Topics: Animals; Indium Radioisotopes; Kidney; Lysine; Male; Octreotide; Pentetic Acid; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Wistar; Tissue Distribution; Yttrium Radioisotopes

1997
Pre-clinical comparison of [DTPA0] octreotide, [DTPA0,Tyr3] octreotide and [DOTA0,Tyr3] octreotide as carriers for somatostatin receptor-targeted scintigraphy and radionuclide therapy.
    International journal of cancer, 1998, Jan-30, Volume: 75, Issue:3

    Topics: Animals; Drug Carriers; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Indium Radioisotopes; Iodine Radioisotopes; Isotope Labeling; Kidney; Male; Mice; Octreotide; Pentetic Acid; Radioisotopes; Radiopharmaceuticals; Rats; Rats, Inbred Lew; Rats, Wistar; Receptors, Somatostatin; Tissue Distribution; Yttrium Radioisotopes

1998
Evaluation of the in vivo biodistribution of yttrium-labeled isomers of CHX-DTPA-conjugated monoclonal antibodies.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1998, Volume: 39, Issue:5

    Topics: Animals; Bone and Bones; Chelating Agents; Female; Isothiocyanates; Mice; Mice, Nude; Pentetic Acid; Radioimmunotherapy; Stereoisomerism; Time Factors; Tissue Distribution; Yttrium Radioisotopes

1998
Synthesis and characterisation of [90Y]-Bz-DTPA-oct: a yttrium-90-labelled octreotide analogue for radiotherapy of somatostatin receptor-positive tumours.
    Nuclear medicine and biology, 1998, Volume: 25, Issue:3

    Topics: Animals; Drug Stability; Half-Life; Humans; Indicators and Reagents; Male; Octreotide; Pancreatic Neoplasms; Pentetic Acid; Radioligand Assay; Radiopharmaceuticals; Rats; Rats, Inbred Lew; Receptors, Somatostatin; Tissue Distribution; Yttrium Radioisotopes

1998
Internalization of radiolabelled [DTPA0]octreotide and [DOTA0,Tyr3]octreotide: peptides for somatostatin receptor-targeted scintigraphy and radionuclide therapy.
    Nuclear medicine communications, 1998, Volume: 19, Issue:3

    Topics: Animals; Binding, Competitive; Biological Transport; Carcinoma; Cell Line; Humans; Indium Radioisotopes; Kinetics; Octreotide; Pancreatic Neoplasms; Pentetic Acid; Radiopharmaceuticals; Rats; Receptors, Somatostatin; Temperature; Thyroid Neoplasms; Tumor Cells, Cultured; Yttrium Radioisotopes

1998
Initial clinical evaluation of radiolabeled MX-DTPA humanized BrE-3 antibody in patients with advanced breast cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:7

    Topics: Adult; Antibodies, Monoclonal; Breast Neoplasms; Female; Humans; Indium Radioisotopes; Middle Aged; Pentetic Acid; Radioimmunotherapy; Radiotherapy Dosage; Tomography, Emission-Computed, Single-Photon; Yttrium Radioisotopes

1998
Physical parameters and biological stability of yttrium(III) diethylenetriaminepentaacetic acid derivative conjugates.
    Journal of medicinal chemistry, 1998, Aug-27, Volume: 41, Issue:18

    Topics: Animals; Chelating Agents; Drug Stability; Hydrogen-Ion Concentration; Mice; Organometallic Compounds; Pentetic Acid; Radiopharmaceuticals; Thermodynamics; Yttrium; Yttrium Radioisotopes

1998
Similarities and differences in 111In- and 90Y-labeled 1B4M-DTPA antiTac monoclonal antibody distribution.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1999, Volume: 40, Issue:2

    Topics: Adult; Antibodies, Monoclonal; Chelating Agents; Female; Humans; Indium Radioisotopes; Leukemia-Lymphoma, Adult T-Cell; Male; Middle Aged; Pentetic Acid; Radioimmunotherapy; Receptors, Interleukin-2; Yttrium Radioisotopes

1999
Treatment of lung tumor colonies with 90Y targeted to blood vessels: comparison with the alpha-particle emitter 213Bi.
    Nuclear medicine and biology, 1999, Volume: 26, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Bismuth; Dose-Response Relationship, Radiation; Female; Isothiocyanates; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, SCID; Pentetic Acid; Radioisotopes; Radiopharmaceuticals; Yttrium Radioisotopes

1999
Yttrium-90-labeled human macroaggregated albumin for internal radiotherapy: combined use with DTPA.
    Nuclear medicine and biology, 1999, Volume: 26, Issue:7

    Topics: Albumins; Animals; Chelating Agents; Female; Humans; Injections, Intraperitoneal; Injections, Intravenous; Lung; Mice; Mice, Inbred BALB C; Pentetic Acid; Radiopharmaceuticals; Radiotherapy Dosage; Tissue Distribution; Yttrium Radioisotopes

1999
In vivo comparison of CHX-DTPA ligand isomers in athymic mice bearing carcinoma xenografts.
    Cancer biotherapy & radiopharmaceuticals, 1999, Volume: 14, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Colonic Neoplasms; Humans; Indium Radioisotopes; Isomerism; Isothiocyanates; Ligands; Mice; Mice, Nude; Pentetic Acid; Radioimmunotherapy; Radiopharmaceuticals; Tissue Distribution; Transplantation, Heterologous; Yttrium Radioisotopes

1999
Radiosensitization of tumor-targeted radioimmunotherapy with prolonged topotecan infusion in human breast cancer xenografts.
    Cancer research, 2001, Apr-01, Volume: 61, Issue:7

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Apoptosis; Bone Marrow; Breast Neoplasms; Cell Division; Combined Modality Therapy; Drug Synergism; Enzyme Inhibitors; Female; Humans; Immunoglobulin G; Immunotoxins; Mice; Mice, Nude; Pentetic Acid; Radiation Tolerance; Radioimmunotherapy; Topotecan; Tumor Cells, Cultured; Xenograft Model Antitumor Assays; Yttrium Radioisotopes

2001
Evaluation of 90Y-DTPA and 90Y-DOTA for potential application in intra-vascular radionuclide therapy.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2002, Volume: 57, Issue:3

    Topics: Angioplasty, Balloon, Coronary; Animals; Brachytherapy; Coronary Vessels; Heterocyclic Compounds, 1-Ring; Humans; Kidney; Mice; Pentetic Acid; Radiopharmaceuticals; Stents; Tissue Distribution; Yttrium Radioisotopes

2002
90Y-DOTA-hLL2: an agent for radioimmunotherapy of non-Hodgkin's lymphoma.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2003, Volume: 44, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Drug Stability; Female; Heterocyclic Compounds, 1-Ring; Humans; In Vitro Techniques; Isotope Labeling; Lymphoma, B-Cell; Lymphoma, Non-Hodgkin; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Pentetic Acid; Radioimmunotherapy; Radiopharmaceuticals; Reference Values; Tissue Distribution; Tumor Cells, Cultured; Yttrium Radioisotopes

2003
Preclinical studies targeting normal and leukemic hematopoietic cells with Yttrium-90-labeled anti-CD45 antibody in vitro and in vivo in nude mice.
    Cancer biotherapy & radiopharmaceuticals, 2003, Volume: 18, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Burkitt Lymphoma; Drug Evaluation, Preclinical; Female; Hematopoietic Stem Cells; Humans; Indium Radioisotopes; Leukemia, Myeloid; Leukocyte Common Antigens; Mice; Mice, Inbred C57BL; Mice, Nude; Pentetic Acid; Radioimmunotherapy; Tissue Distribution; Tumor Cells, Cultured; Yttrium Radioisotopes

2003
Labeling anti-HER2/neu monoclonal antibodies with 111In and 90Y using a bifunctional DTPA chelating agent.
    Cancer biotherapy & radiopharmaceuticals, 2003, Volume: 18, Issue:3

    Topics: Antibodies, Monoclonal; Breast Neoplasms; Female; Humans; Immunoconjugates; Immunoglobulin G; Indium Radioisotopes; Isothiocyanates; Isotope Labeling; Pentetic Acid; Receptor, ErbB-2; Stereoisomerism; Tumor Cells, Cultured; Yttrium Radioisotopes

2003
Optimization of radioimmunotherapy of renal cell carcinoma: labeling of monoclonal antibody cG250 with 131I, 90Y, 177Lu, or 186Re.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2004, Volume: 45, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Carcinoma, Renal Cell; Humans; Iodine Radioisotopes; Isotope Labeling; Kidney Neoplasms; Lutetium; Mice; Mice, Nude; Pentetic Acid; Radioimmunotherapy; Radioisotopes; Rhenium; Tissue Distribution; Yttrium Radioisotopes

2004
Reduction of skeletal accumulation of radioactivity by co-injection of DTPA in [90Y-DOTA0,Tyr3]octreotide solutions containing free 90Y3+.
    Nuclear medicine and biology, 2004, Volume: 31, Issue:6

    Topics: Animals; Autoradiography; Bone and Bones; Chelating Agents; Male; Octreotide; Pentetic Acid; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Inbred Lew; Tissue Distribution; Yttrium Radioisotopes

2004
A single treatment of yttrium-90-labeled CHX-A"-C6.5 diabody inhibits the growth of established human tumor xenografts in immunodeficient mice.
    Cancer research, 2004, Sep-01, Volume: 64, Issue:17

    Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Immunoglobulin Variable Region; Immunotoxins; Isothiocyanates; Mice; Mice, Nude; Mice, SCID; Ovarian Neoplasms; Pentetic Acid; Radioimmunotherapy; Radionuclide Imaging; Receptor, ErbB-2; Tissue Distribution; Xenograft Model Antitumor Assays; Yttrium Radioisotopes

2004
Identification of a novel prostate tumor target, mindin/RG-1, for antibody-based radiotherapy of prostate cancer.
    Cancer research, 2005, Sep-15, Volume: 65, Issue:18

    Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antibody Specificity; Bone Neoplasms; CHO Cells; Cricetinae; Dose-Response Relationship, Immunologic; Extracellular Matrix Proteins; Humans; Immunotoxins; Isothiocyanates; Male; Molecular Sequence Data; Pentetic Acid; Positron-Emission Tomography; Prostatic Neoplasms; Radioimmunotherapy; RNA, Messenger; Tissue Distribution; Xenograft Model Antitumor Assays; Yttrium Radioisotopes

2005
Enhanced efficacy of radioimmunotherapy with 90Y-CHX-A''-DTPA-hu3S193 by inhibition of epidermal growth factor receptor (EGFR) signaling with EGFR tyrosine kinase inhibitor AG1478.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Oct-01, Volume: 11, Issue:19 Pt 2

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Cell Line, Tumor; Enzyme Inhibitors; ErbB Receptors; Female; Humans; Lewis Blood Group Antigens; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Pentetic Acid; Protein-Tyrosine Kinases; Quinazolines; Radioimmunotherapy; Radiopharmaceuticals; Signal Transduction; Time Factors; Tissue Distribution; Tyrphostins; Yttrium Radioisotopes

2005
Validation of a novel CHX-A'' derivative suitable for peptide conjugation: small animal PET/CT imaging using yttrium-86-CHX-A''-octreotide.
    Journal of medicinal chemistry, 2006, Jul-13, Volume: 49, Issue:14

    Topics: Animals; Isothiocyanates; Isotope Labeling; Male; Neoplasm Transplantation; Neoplasms, Experimental; Octreotide; Pentetic Acid; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Rats, Inbred Lew; Tissue Distribution; Yttrium Radioisotopes

2006
[Labeling of CDTPA-dianhydride-coupled CD45 monoclonal antibody with yttrium-90].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2006, Volume: 26, Issue:8

    Topics: Anhydrides; Antibodies, Monoclonal; Humans; Immunoconjugates; Isotope Labeling; Leukocyte Common Antigens; Pentetic Acid; Radiopharmaceuticals; Yttrium Radioisotopes

2006
Design, synthesis, and characterization of a dual modality positron emission tomography and fluorescence imaging agent for monoclonal antibody tumor-targeted imaging.
    Journal of medicinal chemistry, 2007, Sep-20, Volume: 50, Issue:19

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Binding, Competitive; Carbocyanines; Cell Line, Tumor; Chelating Agents; Drug Design; Flow Cytometry; Fluorescent Dyes; Humans; Immunoconjugates; Indium Radioisotopes; Isothiocyanates; Lysine; Pentetic Acid; Positron-Emission Tomography; Radioimmunoassay; Radiopharmaceuticals; Trastuzumab; Yttrium Radioisotopes

2007
Yttrium-86-labelled human serum albumin microspheres: relation of surface structure with in vivo stability.
    Nuclear medicine and biology, 2008, Volume: 35, Issue:2

    Topics: Albumins; Animals; Chelating Agents; Drug Stability; Heterocyclic Compounds; Humans; Isotope Labeling; Lung; Metabolic Clearance Rate; Microspheres; Organometallic Compounds; Pentetic Acid; Plasma; Radionuclide Imaging; Radiopharmaceuticals; Rats; Surface Properties; Tissue Distribution; Yttrium Radioisotopes

2008
In vivo biodistribution, PET imaging, and tumor accumulation of 86Y- and 111In-antimindin/RG-1, engineered antibody fragments in LNCaP tumor-bearing nude mice.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2009, Volume: 50, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Cell Line, Tumor; Chelating Agents; Humans; Indium Radioisotopes; Isothiocyanates; Male; Mice; Mice, Nude; Neoplasm Transplantation; Pentetic Acid; Positron-Emission Tomography; Prostatic Neoplasms; Radiopharmaceuticals; Tissue Distribution; Tomography, X-Ray Computed; Transplantation, Heterologous; Yttrium Radioisotopes

2009
PET imaging of HER1-expressing xenografts in mice with 86Y-CHX-A''-DTPA-cetuximab.
    European journal of nuclear medicine and molecular imaging, 2010, Volume: 37, Issue:7

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Cell Line, Tumor; Cell Transformation, Neoplastic; Cetuximab; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Humans; Isothiocyanates; Mice; Neoplasms; Pentetic Acid; Positron-Emission Tomography; Radiochemistry; Yttrium Radioisotopes

2010
PET imaging of tumor angiogenesis in mice with VEGF-A-targeted (86)Y-CHX-A″-DTPA-bevacizumab.
    International journal of cancer, 2011, Feb-15, Volume: 128, Issue:4

    Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Bevacizumab; Colorectal Neoplasms; Female; Humans; Immunoconjugates; Isothiocyanates; Mice; Mice, Nude; Neovascularization, Pathologic; Ovarian Neoplasms; Pentetic Acid; Positron-Emission Tomography; Radioimmunoassay; Radiopharmaceuticals; Tissue Distribution; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Yttrium Radioisotopes

2011
Preparation, biological evaluation, and pharmacokinetics of the human anti-HER1 monoclonal antibody panitumumab labeled with 86Y for quantitative PET of carcinoma.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2010, Volume: 51, Issue:6

    Topics: Animals; Antibodies, Monoclonal; Area Under Curve; Biological Transport; Cell Line, Tumor; Cell Transformation, Neoplastic; ErbB Receptors; Female; Humans; Mice; Neoplasms; Panitumumab; Pentetic Acid; Positron-Emission Tomography; Radiochemistry; Risk Assessment; Yttrium Radioisotopes

2010
HER1-targeted 86Y-panitumumab possesses superior targeting characteristics than 86Y-cetuximab for PET imaging of human malignant mesothelioma tumors xenografts.
    PloS one, 2011, Mar-25, Volume: 6, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibody Specificity; Cetuximab; ErbB Receptors; Flow Cytometry; Humans; Isothiocyanates; Mesothelioma; Mice; Molecular Targeted Therapy; Panitumumab; Pentetic Acid; Positron-Emission Tomography; Time Factors; Tissue Distribution; Xenograft Model Antitumor Assays; Yttrium Radioisotopes

2011
Flow cytometric cell-based assay to preselect antibody constructs for radionuclide conjugation.
    Cytometry. Part A : the journal of the International Society for Analytical Cytology, 2012, Volume: 81, Issue:10

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Binding, Competitive; Cell Line, Tumor; Cetuximab; Chelating Agents; Drug Carriers; ErbB Receptors; Flow Cytometry; Fluorescence; Humans; Immunoassay; Immunoconjugates; Isothiocyanates; Pentetic Acid; Protein Binding; Radiopharmaceuticals; Yttrium Radioisotopes

2012
Radiolabeled anti-EGFR-antibody improves local tumor control after external beam radiotherapy and offers theragnostic potential.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2014, Volume: 110, Issue:2

    Topics: Animals; Antibodies, Monoclonal, Humanized; Carcinoma, Squamous Cell; Cell Line, Tumor; Cetuximab; ErbB Receptors; Female; Humans; Immunotoxins; Isothiocyanates; Male; Mice; Mice, Nude; Pentetic Acid; Radioimmunotherapy; Radiopharmaceuticals; Random Allocation; Tissue Distribution; Yttrium Radioisotopes

2014
166Ho and 90Y labeled 6D2 monoclonal antibody for targeted radiotherapy of melanoma: comparison with 188Re radiolabel.
    Nuclear medicine and biology, 2014, Volume: 41, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Cell Line, Tumor; Drug Stability; Female; Half-Life; Holmium; Humans; Melanoma, Experimental; Mice; Mice, Nude; Pentetic Acid; Radioimmunotherapy; Tissue Distribution; Yttrium Radioisotopes

2014
Cytotoxic properties of radionuclide-conjugated Cetuximab without and in combination with external irradiation in head and neck cancer cells in vitro.
    International journal of radiation biology, 2014, Volume: 90, Issue:8

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Cell Count; Cell Line, Tumor; Cell Survival; Cetuximab; Combined Modality Therapy; DNA Breaks, Double-Stranded; ErbB Receptors; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Intracellular Space; Molecular Targeted Therapy; Pentetic Acid; Phosphorylation; Protein Transport; Signal Transduction; Yttrium Radioisotopes

2014
A systematic comparative evaluation of 90Y-labeled bifunctional chelators for their use in targeted therapy.
    Journal of labelled compounds & radiopharmaceuticals, 2014, Volume: 57, Issue:2

    Topics: Acetates; Animals; Bridged Bicyclo Compounds, Heterocyclic; Chelating Agents; Humans; Mice; Pentetic Acid; Radiopharmaceuticals; Yttrium Radioisotopes

2014
A comparative evaluation of the chelators H4octapa and CHX-A″-DTPA with the therapeutic radiometal (90)Y.
    Nuclear medicine and biology, 2016, Volume: 43, Issue:9

    Topics: Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Chelating Agents; Ethylamines; Female; Isothiocyanates; Isotope Labeling; Mice; Pentetic Acid; Positron-Emission Tomography; Pyridines; Radioimmunotherapy; Tissue Distribution; Trastuzumab; Yttrium Radioisotopes

2016
Optimization of the radiolabelling method for improved in vitro and in vivo stability of
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2020, Volume: 156

    Topics: Albumins; Animals; Chelating Agents; Male; Microspheres; Pentetic Acid; Radiopharmaceuticals; Rats; Rats, Wistar; Yttrium Radioisotopes

2020