pentetic acid and epidermal growth factor

pentetic acid has been researched along with epidermal growth factor in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (20.00)18.2507
2000's12 (48.00)29.6817
2010's8 (32.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alcain, FJ; Crane, FL; Löw, H1
Gamberini, M; Leite, LC1
Kennedy, DO; Matsui-Yuasa, I; Murakami, Y; Nakatani, T; Otani, S; Yano, Y1
Browning, JD; MacDonald, RS; O'Dell, BL; Thornton, WH; Wollard-Biddle, LC1
Kurihara, A; Pardridge, WM1
Cameron, RG; Gariépy, J; Hendler, A; Kiarash, R; Lee, YW; Reilly, RM; Sandhu, J; Vallis, K1
Bruskin, A; Gedda, L; Lundqvist, H; Orlova, A; Sjöström, A; Tolmachev, V1
Cameron, R; Chen, P; Hendler, A; Mrkobrada, M; Reilly, RM; Sandhu, J; Vallis, KA1
Cameron, R; Chen, P; Reilly, RM; Vallis, KA; Wang, J1
Blomquist, E; Bruskin, A; Carlsson, J; Gedda, L; Lundqvist, H; Orlova, A; Sundberg, AL; Tolmachev, V1
Blomquist, E; Bruskin, A; Carlsson, J; Gedda, L; Orlova, A; Sundberg, AL; Tolmachev, V1
Bruskin, A; Carlsson, J; Gedda, L; Orlova, A; Tolmachev, V; Wei, Q1
Cameron, R; Chen, P; Reilly, RM; Scollard, D; Vallis, KA; Wang, J1
Bailey, KE; Cai, Z; Chen, Z; Costantini, DL; Reilly, RM; Scollard, DA; Vallis, KA1
Chan, C; Chen, P; Hu, M; Reilly, RM; Scollard, D; Vallis, K1
Bailey, KE; Cai, Z; Chen, Z; Reilly, RM; Scollard, DA; Vallis, KA1
Cai, Z; Reilly, RM; Vallis, KA1
Allen, C; Fonge, H; Lee, H; Reilly, RM1
Cai, Z; Chan, C; Pignol, JP; Reilly, RM1
Barber, PR; Cornelissen, B; Darbar, S; Hernandez, R; Kersemans, V; Reilly, R; Smart, S; Tullis, I; Vallis, KA; Vojnovic, B1
Browning, JD; O'Dell, BL1
Allen, C; Fonge, H; Huang, H; Reilly, RM; Scollard, D1
Terry, SY; Vallis, KA1
Altebaeumer, T; Chakalova, R; Falzone, N; Myhra, S; Nathan, R; Royle, G; Vallis, KA1
Chang, CA; Chang, SF; Chen, YF; Chiang, PH; Fischer, WB; Lan, KL; Li, JJ; Lin, MH; Liu, RS; Shih, YS; Tsai, WC; Tsay, YG; Wang, HE; Yen, SH1

Other Studies

25 other study(ies) available for pentetic acid and epidermal growth factor

ArticleYear
Iron reverses impermeable chelator inhibition of DNA synthesis in CCl 39 cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Aug-16, Volume: 91, Issue:17

    Topics: Animals; Cations, Divalent; Cell Line; Chelating Agents; Cricetinae; Cricetulus; DNA; DNA Replication; Electron Transport; Epidermal Growth Factor; Hydroxyurea; Iron; Kinetics; Lung; Pentetic Acid; Phenanthrolines; Thymidine

1994
Proliferation of mouse fibroblasts induced by 1,2-dimethylhydrazine auto-oxidation: role of iron and free radicals.
    Biochemical and biophysical research communications, 1997, May-08, Volume: 234, Issue:1

    Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Catalase; Cell Division; Cell Line; Chelating Agents; Dimethylhydrazines; DNA; Epidermal Growth Factor; Free Radical Scavengers; Free Radicals; Insulin; Iron; Mannitol; Mice; Mutagens; Oxidation-Reduction; Pentetic Acid; Reactive Oxygen Species; Superoxide Dismutase

1997
Restricted Zn2+ availability affects the antizyme-dependent ornithine decarboxylase degradation pathway in isolated primary cultured rat hepatocytes.
    Biochemical and biophysical research communications, 1998, Feb-24, Volume: 243, Issue:3

    Topics: Animals; Blotting, Western; Cells, Cultured; Chelating Agents; Enzyme Inhibitors; Epidermal Growth Factor; Insulin; Liver; Ornithine Decarboxylase; Pentetic Acid; Rats; RNA, Messenger; Zinc

1998
Zinc deprivation of murine 3T3 cells by use of diethylenetrinitrilopentaacetate impairs DNA synthesis upon stimulation with insulin-like growth factor-1 (IGF-1).
    The Journal of nutrition, 1998, Volume: 128, Issue:10

    Topics: 3T3 Cells; Animals; Cells, Cultured; Chelating Agents; DNA; Epidermal Growth Factor; Insulin-Like Growth Factor I; Mice; Pentetic Acid; Platelet-Derived Growth Factor; Thymidine; Zinc

1998
Imaging brain tumors by targeting peptide radiopharmaceuticals through the blood-brain barrier.
    Cancer research, 1999, Dec-15, Volume: 59, Issue:24

    Topics: Animals; Biotinylation; Blood-Brain Barrier; Brain Neoplasms; Epidermal Growth Factor; ErbB Receptors; Humans; Indium Radioisotopes; Mice; Mice, Nude; Neoplasm Transplantation; Pentetic Acid; Peptides; Radionuclide Imaging; Radiopharmaceuticals; Tumor Cells, Cultured

1999
A comparison of EGF and MAb 528 labeled with 111In for imaging human breast cancer.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2000, Volume: 41, Issue:5

    Topics: Animals; Antibodies, Monoclonal; Breast Neoplasms; Epidermal Growth Factor; ErbB Receptors; Female; Humans; Indium Radioisotopes; Mice; Mice, Nude; Neoplasm Transplantation; Pentetic Acid; Radionuclide Imaging; Radiopharmaceuticals; Tumor Cells, Cultured

2000
Cellular processing of (125)I- and (111)in-labeled epidermal growth factor (EGF) bound to cultured A431 tumor cells.
    Nuclear medicine and biology, 2000, Volume: 27, Issue:8

    Topics: Chelating Agents; Chromatography, High Pressure Liquid; Epidermal Growth Factor; Humans; Indium Radioisotopes; Iodine Radioisotopes; Iodobenzoates; Isotope Labeling; Kinetics; Pentetic Acid; Radiopharmaceuticals; Tumor Cells, Cultured

2000
Comparative antiproliferative effects of (111)In-DTPA-hEGF, chemotherapeutic agents and gamma-radiation on EGFR-positive breast cancer cells.
    Nuclear medicine and biology, 2002, Volume: 29, Issue:6

    Topics: Antineoplastic Agents; Biomarkers, Tumor; Breast Neoplasms; Doxorubicin; Epidermal Growth Factor; ErbB Receptors; Gamma Rays; Humans; Methotrexate; Pentetic Acid; Radiopharmaceuticals; Treatment Outcome; Tumor Cells, Cultured

2002
Antitumor effects and normal tissue toxicity of 111In-labeled epidermal growth factor administered to athymic mice bearing epidermal growth factor receptor-positive human breast cancer xenografts.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2003, Volume: 44, Issue:9

    Topics: Animals; Biomarkers, Tumor; Breast Neoplasms; Dose-Response Relationship, Radiation; Drug Delivery Systems; Epidermal Growth Factor; ErbB Receptors; Female; Humans; Metabolic Clearance Rate; Mice; Mice, Nude; Neoplasm Transplantation; Organ Specificity; Pentetic Acid; Radiopharmaceuticals; Tissue Distribution; Treatment Outcome

2003
[(111)In]Bz-DTPA-hEGF: Preparation and in vitro characterization of a potential anti-glioblastoma targeting agent.
    Cancer biotherapy & radiopharmaceuticals, 2003, Volume: 18, Issue:4

    Topics: Binding, Competitive; Cell Line, Tumor; Drug Delivery Systems; Drug Stability; Endocytosis; Epidermal Growth Factor; ErbB Receptors; Glioblastoma; Humans; Indium Radioisotopes; Isothiocyanates; Kinetics; Pentetic Acid; Protein Binding; Protein Transport; Recombinant Proteins; Thiocyanates; Time Factors

2003
[177Lu]Bz-DTPA-EGF: Preclinical characterization of a potential radionuclide targeting agent against glioma.
    Cancer biotherapy & radiopharmaceuticals, 2004, Volume: 19, Issue:2

    Topics: Animals; Cell Line, Tumor; Chelating Agents; Drug Evaluation, Preclinical; Epidermal Growth Factor; Glioblastoma; Humans; Lutetium; Mice; Mice, Inbred Strains; Pentetic Acid; Protein Binding; Radioisotopes; Radiopharmaceuticals; Sensitivity and Specificity; Tissue Distribution

2004
Comparative biodistribution of potential anti-glioblastoma conjugates [111In]DTPA-hEGF and [111In]Bz-DTPA-hEGF in normal mice.
    Cancer biotherapy & radiopharmaceuticals, 2004, Volume: 19, Issue:4

    Topics: Animals; Epidermal Growth Factor; ErbB Receptors; Female; Glioblastoma; Indium Radioisotopes; Isothiocyanates; Mice; Pentetic Acid; Radiopharmaceuticals

2004
Preclinical pharmacokinetic, biodistribution, toxicology, and dosimetry studies of 111In-DTPA-human epidermal growth factor: an auger electron-emitting radiotherapeutic agent for epidermal growth factor receptor-positive breast cancer.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2006, Volume: 47, Issue:6

    Topics: Animals; Body Burden; Breast Neoplasms; Drug Evaluation, Preclinical; Electrons; Epidermal Growth Factor; Female; Maximum Tolerated Dose; Metabolic Clearance Rate; Mice; Mice, Inbred BALB C; Organ Specificity; Pentetic Acid; Rabbits; Radionuclide Imaging; Radiopharmaceuticals; Radiotherapy Dosage; Tissue Distribution; Treatment Outcome

2006
Epidermal growth factor receptor inhibition modulates the nuclear localization and cytotoxicity of the Auger electron emitting radiopharmaceutical 111In-DTPA human epidermal growth factor.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2007, Volume: 48, Issue:9

    Topics: Antineoplastic Agents; Cell Compartmentation; Cell Line, Tumor; Cell Nucleus; Electrons; Epidermal Growth Factor; ErbB Receptors; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Gefitinib; Humans; Indium Radioisotopes; Pentetic Acid; Phosphorylation; Protein Transport; Quinazolines; Radiopharmaceuticals; Signal Transduction

2007
Effect of the EGFR density of breast cancer cells on nuclear importation, in vitro cytotoxicity, and tumor and normal-tissue uptake of [111In]DTPA-hEGF.
    Nuclear medicine and biology, 2007, Volume: 34, Issue:8

    Topics: Breast Neoplasms; Cell Line, Tumor; Cell Nucleus; Cell Survival; Dose-Response Relationship, Radiation; Epidermal Growth Factor; ErbB Receptors; Humans; Organ Specificity; Pentetic Acid; Radiopharmaceuticals; Reference Values; Tissue Distribution

2007
Relationship between induction of phosphorylated H2AX and survival in breast cancer cells exposed to 111In-DTPA-hEGF.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2008, Volume: 49, Issue:8

    Topics: Active Transport, Cell Nucleus; Breast Neoplasms; Cell Line, Tumor; Cell Nucleus; Cell Survival; DNA Damage; Epidermal Growth Factor; ErbB Receptors; Female; Gamma Rays; Histones; Humans; Indium Radioisotopes; Pentetic Acid; Phosphorylation; Radiopharmaceuticals

2008
Computational analysis of the number, area and density of gamma-H2AX foci in breast cancer cells exposed to (111)In-DTPA-hEGF or gamma-rays using Image-J software.
    International journal of radiation biology, 2009, Volume: 85, Issue:3

    Topics: Breast Neoplasms; Cell Line, Tumor; Cell Nucleus; DNA Breaks, Double-Stranded; Dose-Response Relationship, Radiation; Epidermal Growth Factor; Female; Gamma Rays; Histones; Humans; Indium Radioisotopes; Pentetic Acid; Phosphorylation; Radiopharmaceuticals; Software

2009
Multifunctional block copolymer micelles for the delivery of 111In to EGFR-positive breast cancer cells for targeted Auger electron radiotherapy.
    Molecular pharmaceutics, 2010, Feb-01, Volume: 7, Issue:1

    Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Delivery Systems; Electrons; Epidermal Growth Factor; ErbB Receptors; Female; Humans; Indium Radioisotopes; Micelles; Pentetic Acid; Polymers; Radiopharmaceuticals; Tumor Stem Cell Assay

2010
Cellular dosimetry of (111)In using monte carlo N-particle computer code: comparison with analytic methods and correlation with in vitro cytotoxicity.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2010, Volume: 51, Issue:3

    Topics: Cell Line, Tumor; Cell Nucleus; Cell Survival; Cytoplasm; Epidermal Growth Factor; Humans; Indium Radioisotopes; Models, Biological; Molecular Imaging; Monte Carlo Method; Pentetic Acid; Programming Languages; Radiometry

2010
ErbB-2 blockade and prenyltransferase inhibition alter epidermal growth factor and epidermal growth factor receptor trafficking and enhance (111)In-DTPA-hEGF Auger electron radiation therapy.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2011, Volume: 52, Issue:5

    Topics: Active Transport, Cell Nucleus; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Colony-Forming Units Assay; Dimethylallyltranstransferase; Electrons; Epidermal Growth Factor; ErbB Receptors; Female; Humans; Imidazoles; Mice; Pentetic Acid; Protein Kinase Inhibitors; Protein Transport; Receptor, ErbB-2; Signal Transduction; Trastuzumab

2011
Zinc deprivation impairs growth factor-stimulated calcium influx into murine 3T3 cells associated with decreased cell proliferation.
    The Journal of nutrition, 2011, Volume: 141, Issue:6

    Topics: Animals; Becaplermin; Calcium Channel Blockers; Calcium Signaling; Cell Proliferation; Chelating Agents; Epidermal Growth Factor; Growth Substances; Insulin-Like Growth Factor I; Mice; Pentetic Acid; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Recombinant Proteins; Swiss 3T3 Cells; Verapamil; Zinc

2011
Influence of formulation variables on the biodistribution of multifunctional block copolymer micelles.
    Journal of controlled release : official journal of the Controlled Release Society, 2012, Feb-10, Volume: 157, Issue:3

    Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Chelating Agents; Chemistry, Pharmaceutical; Epidermal Growth Factor; Heterocyclic Compounds, 1-Ring; Humans; Mice; Mice, Nude; Micelles; Neoplasm Transplantation; Pentetic Acid; Polymers; Tissue Distribution

2012
Relationship between chromatin structure and sensitivity to molecularly targeted auger electron radiation therapy.
    International journal of radiation oncology, biology, physics, 2012, Jul-15, Volume: 83, Issue:4

    Topics: Analysis of Variance; Azacitidine; Cell Line, Tumor; Chromatin; Decitabine; DNA Damage; Electrons; Epidermal Growth Factor; ErbB Receptors; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Pentetic Acid; Radiation Tolerance; Radiopharmaceuticals; Radiotherapy; Sodium Chloride; Vorinostat

2012
Photoresists as a high spatial resolution autoradiography substrate for quantitative mapping of intra- and sub-cellular distribution of Auger electron emitting radionuclides.
    International journal of radiation biology, 2012, Volume: 88, Issue:12

    Topics: Autoradiography; Biological Transport; Cell Line, Tumor; Cell Nucleus; Electrons; Epidermal Growth Factor; Humans; Indium Radioisotopes; Intracellular Space; Monte Carlo Method; Pentetic Acid; Polymethyl Methacrylate

2012
Development and Characterization of the Recombinant Human VEGF-EGF Dual-Targeting Fusion Protein as a Drug Delivery System.
    Bioconjugate chemistry, 2015, Dec-16, Volume: 26, Issue:12

    Topics: Animals; Antineoplastic Agents; Cattle; Cell Line; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Epidermal Growth Factor; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Pentetic Acid; Recombinant Fusion Proteins; Vascular Endothelial Growth Factor A

2015