pentamidine and thiophenes

pentamidine has been researched along with thiophenes in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's3 (37.50)29.6817
2010's2 (25.00)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Delmas, F; Gasquet, M; Madadi, NE; Maldonado, J; Savornin, B; Timon-David, P; Vanelle, P1
Boykin, DW; Brendle, JJ; Kumar, A; Outlaw, A; Patrick, DA; Tidwell, RR; Werbovetz, KA1
Bailly, C; Boykin, DW; Kumar, A; Lee, MP; Mallena, S; Neidle, S; Wilson, WD1
Boykin, DW; Collar, CJ; Kumar, A; Liu, Y; Stephens, CE; Wilson, WD1
Bajić, M; Glavaš-Obrovac, L; Lončar, MB; Mišković, K; Piantanida, I; Stolić, I1
Bajić, M; Crispim, M; Damasceno, FS; Elias, MC; Girard, RM; Pral, EM; Santos da Silva, M; Silber, AM; Stolić, I1
Boykin, DW; Farahat, AA; Guo, P; Paul, A; Shoeib, H; Wilson, WD1
Boykin, DW; Chen, C; Fang, Z; Ogbonna, EN; Paul, A; Poon, GMK; Ross Terrell, J; Wilson, WD1

Other Studies

8 other study(ies) available for pentamidine and thiophenes

ArticleYear
Evaluation of in-vitro leishmanicidal activity of hydrazones of thiophene carboxaldehydes against promastigotes of Leishmania infantum and Leishmania tropica.
    The Journal of pharmacy and pharmacology, 1991, Volume: 43, Issue:1

    Topics: Animals; Antiprotozoal Agents; Hydrazones; Leishmania donovani; Leishmania tropica; Microbial Sensitivity Tests; Pentamidine; Rabbits; Structure-Activity Relationship; Thiophenes

1991
Antileishmanial activities of several classes of aromatic dications.
    Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:3

    Topics: Adult; Animals; Antiprotozoal Agents; Benzimidazoles; Carbazoles; Cations; Cell Division; Furans; Humans; In Vitro Techniques; Indicators and Reagents; Leishmania donovani; Leishmania mexicana; Macrophages; Mice; Pentamidine; Structure-Activity Relationship; Thiophenes

2002
Thiophene-based diamidine forms a "super" at binding minor groove agent.
    Journal of the American Chemical Society, 2004, Oct-27, Volume: 126, Issue:42

    Topics: Adenine; Animals; Base Pairing; Benzamidines; Biosensing Techniques; Calorimetry; Cattle; Chemical Phenomena; Chemistry, Physical; Circular Dichroism; Crystallography, X-Ray; Deoxyribonuclease I; DNA; DNA Footprinting; Models, Molecular; Nucleic Acid Conformation; Pentamidine; Surface Plasmon Resonance; Thermodynamics; Thiophenes; Thymine; Titrimetry

2004
Heterocyclic diamidine interactions at AT base pairs in the DNA minor groove: effects of heterocycle differences, DNA AT sequence and length.
    The journal of physical chemistry. B, 2008, Sep-18, Volume: 112, Issue:37

    Topics: Adenine; Base Pairing; Base Sequence; Binding Sites; Calorimetry; Circular Dichroism; DNA; Furans; Heterocyclic Compounds; Hydrogen Bonding; Models, Molecular; Organoselenium Compounds; Pentamidine; Surface Plasmon Resonance; Thermodynamics; Thiophenes; Thymine

2008
Synthesis, DNA/RNA affinity and antitumour activity of new aromatic diamidines linked by 3,4-ethylenedioxythiophene.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Animals; Antineoplastic Agents; Binding Sites; Cell Cycle; Cell Proliferation; Cells, Cultured; DNA; Dogs; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Molecular Structure; Pentamidine; RNA; Stereoisomerism; Structure-Activity Relationship; Thiophenes

2011
An Aromatic Diamidine That Targets Kinetoplast DNA, Impairs the Cell Cycle in Trypanosoma cruzi, and Diminishes Trypomastigote Release from Infected Mammalian Host Cells.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:10

    Topics: Animals; Benzamidines; Cell Cycle; CHO Cells; Cricetulus; DNA, Kinetoplast; Molecular Structure; Pentamidine; Thiophenes; Trypanocidal Agents; Trypanosoma cruzi

2016
Small Sequence-Sensitive Compounds for Specific Recognition of the G⋅C Base Pair in DNA Minor Groove.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2020, Apr-06, Volume: 26, Issue:20

    Topics: Base Pairing; Biosensing Techniques; Circular Dichroism; DNA; Pentamidine; Spectrometry, Fluorescence; Thiophenes

2020
Drug design and DNA structural research inspired by the Neidle laboratory: DNA minor groove binding and transcription factor inhibition by thiophene diamidines.
    Bioorganic & medicinal chemistry, 2022, 08-15, Volume: 68

    Topics: Benzimidazoles; Binding Sites; DNA; Drug Design; Indoles; Models, Molecular; Nucleic Acid Conformation; Pentamidine; Surface Plasmon Resonance; Thiophenes; Transcription Factors

2022