pentamidine and nifurtimox

pentamidine has been researched along with nifurtimox in 34 studies

Research

Studies (34)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (8.82)	18.7374
1990's	1 (2.94)	18.2507
2000's	5 (14.71)	29.6817
2010's	24 (70.59)	24.3611
2020's	1 (2.94)	2.80

Authors

Authors	Studies
Baliani, A; Barrett, MP; Brun, R; Bueno, GJ; Gilbert, IH; Stewart, ML; Yardley, V	1
Boiani, L; Boiani, M; Cerecetto, H; Denicola, A; Gómez-Barrio, A; Gonzalez, M; Nakayama, H; Rojas de Arias, A; Rolan, M; Sanabria, L; Serna, E; Torres de Ortiz, S; Vega, C; Vera de Bilbao, N; Yaluff, G	1
Büchold, C; Gelhaus, C; Gut, J; Kisker, C; Leippe, M; Leyh, M; Machon, U; Rosenthal, PJ; Schirmeister, T; Schmuck, C; Stempka, M	1
Benitez, D; Cerecetto, H; Eifler-Lima, VL; González, M; Graebin, CS; Madeira, Mde F; Miguel, DC; Rosa, RG; Uliana, SR; Yokoyama-Yasunaka, JK	1
Breuning, A; Büchold, C; Degel, B; Gelhaus, C; Gut, J; Heppner, S; Kisker, C; Leippe, M; Leyh, M; Machon, U; Rath, J; Rosenthal, PJ; Schirmeister, T; Schmuck, C; Schulz, F; Stempka, M; Stich, A	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fairlamb, AH; Oza, SL; Patterson, S; Read, KD; Sokolova, AY; Wyllie, S	1
Caminos, AP; Labadie, GR; Panozzo-Zenere, EA; Tekwani, BL; Wilkinson, SR	1
Rideau, E; Smith, TK; Stewart, G; Westwood, NJ; Zhou, L	1
Bosc, D; Cojean, S; Dubois, J; Franco, CH; Freitas-Junior, LH; Grellier, P; Loiseau, PM; Moraes, CB; Mouray, E	1
Alunda, JM; Baptista, C; Behrens, B; Bifeld, E; Borsari, C; Clos, J; Cordeiro-da-Silva, A; Corral, MJ; Costantino, L; Costi, MP; Dello Iacono, L; Di Pisa, F; Eick, J; Ellinger, B; Ferrari, S; Gribbon, P; Gul, S; Henrich, S; Jiménez-Antón, MD; Keminer, O; Kohler, M; Kuzikov, M; Landi, G; Luciani, R; Mangani, S; Pellati, F; Poehner, I; Pozzi, C; Reinshagen, J; Santarem, N; Tait, A; Tejera Nevado, P; Torrado, J; Trande, M; Wade, RC; Witt, G; Wolf, M	1
Abdeen, S; Chapman, E; Goldsmith-Pestana, K; Horwich, AL; Johnson, SM; Mammadova, N; McMahon-Pratt, D; Salim, N; Schultz, PG; Summers, CM	1
Alcântara, LM; Alunda, JM; Baptista, C; Bertolacini, CD; Borsari, C; Bruno Dos Santos, P; Clos, J; Cordeiro-da-Silva, A; Corral, MJ; Costantino, L; Costi, MP; Ellinger, B; Ferrari, S; Fontana, V; Franco, CH; Freitas-Junior, LH; Gribbon, P; Gul, S; Kuzikov, M; Linciano, P; Moraes, CB; Olías, AI; Reinshagen, J; Santarem, N; Tait, A; Tejera Nevado, P; Torrado, J; Witt, G; Wolf, M	1
Argüello-Garcia, R; Barbosa-Cabrera, E; Chan-Bacab, MJ; Colín-Lozano, B; Hernández-Núñez, E; León-Rivera, I; López-Guerrero, V; Moo-Puc, R; Navarrete-Vázquez, G; Ortega-Morales, BO; Scior, T	1
Brun, R; Diederich, F; Giroud, M; Haap, W; Kaiser, M; Kuhn, B; Kuratli, C; Martin, RE; Saint-Auret, S; Schirmeister, T; Schuler, F	1
Cantizani, J; Cogo, J; Corrêa, AG; Cotillo, I; Filho, BPD; Martín, JJ; Nakamura, CV; Sangi, DP; Ueda-Nakamura, T	1
Azas, N; Basmaciyan, L; Belle Mbou, V; Boudot, C; Bourgeade-Delmas, S; Boutet-Robinet, É; Casanova, M; Castera-Ducros, C; Cohen, A; Courtioux, B; Fairlamb, AH; Fersing, C; Hutter, S; Laget, M; Milne, R; Pedron, J; Piednoel, M; Primas, N; Rathelot, P; Since, M; Sournia-Saquet, A; Valentin, A; Vanelle, P; Verhaeghe, P; Wyllie, S	1
Grellier, P; Gzella, A; Kaminskyy, D; Karpenko, O; Kryshchyshyn, A; Lesyk, R	1
Choongo, K; Ishikawa, Y; Kikuchi, T; Munsimbwe, L; Murata, T; Shirakura, I; Suganuma, K	1
Duke, BO	1
Lefrock, JL; Smith, BR	1
Gutteridge, WE	1
Milord, F; Pépin, J	1
De Koning, HP; Dogruel, M; Rodgers, J; Sanderson, L; Thomas, SA	1
Schlitzer, M	1
Kennedy, A; Lutje, V; Seixas, J	2
Barrett, MP	1
Barrett, MP; Burchmore, RJ; Kazibwe, AJ; Matovu, E; Vincent, IM	1
Alsford, S; Baker, N; Berriman, M; Eckert, S; Field, MC; Glover, L; Horn, D; Leung, KF; Sanchez-Flores, A; Turner, DJ	1
Bucheton, B; Courtois, P; Cuny, G; Daulouède, S; Dethoua, M; Nzoumbou-Boko, R; Semballa, S; Truc, P; Vincendeau, P	1
Chiodini, PL; Fink, D; Hedley, L; Sparkes, D	1
Alsford, S; Baker, N; Dominicus, C; Glover, L; Horn, D; Hutchinson, S; Thomas, JA; Trenaman, A	1

Reviews

7 review(s) available for pentamidine and nifurtimox

Article	Year
Existing chemotherapy and its limitations. British medical bulletin, 1985, Volume: 41, Issue:2 Topics: Chagas Disease; Gentian Violet; Humans; Melarsoprol; Nifurtimox; Nitroimidazoles; Pentamidine; Suramin; Trypanocidal Agents; Trypanosomiasis, African	1985
The treatment of human African trypanosomiasis. Advances in parasitology, 1994, Volume: 33 Topics: Animals; Diminazene; Eflornithine; Humans; Melarsoprol; Nifurtimox; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	1994
[Agents for the treatment of African sleeping sickness. Those developed in the last century]. Pharmazie in unserer Zeit, 2009, Volume: 38, Issue:6 Topics: Animals; Eflornithine; History, 20th Century; Humans; Melarsoprol; Nifurtimox; Pentamidine; Suramin; Trypanocidal Agents; Trypanosomiasis, African	2009
Chemotherapy for second-stage Human African trypanosomiasis. The Cochrane database of systematic reviews, 2010, Aug-04, Issue:8 Topics: Animals; Antiprotozoal Agents; Drug Therapy, Combination; Eflornithine; Humans; Melarsoprol; Nifurtimox; Pentamidine; Prednisolone; Randomized Controlled Trials as Topic; Recurrence; Trypanosoma brucei gambiense; Trypanosomiasis, African	2010
Potential new drugs for human African trypanosomiasis: some progress at last. Current opinion in infectious diseases, 2010, Volume: 23, Issue:6 Topics: Animals; Benzamides; Boron Compounds; Drug Discovery; Drug Resistance; Drug Therapy, Combination; Eflornithine; Humans; Melarsoprol; Mice; Nifurtimox; Nitroimidazoles; Pentamidine; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	2010
Drug resistance in human African trypanosomiasis. Future microbiology, 2011, Volume: 6, Issue:9 Topics: Animals; Drug Resistance; Eflornithine; Humans; Membrane Transport Proteins; Nifurtimox; Pentamidine; Protozoan Proteins; Treatment Failure; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African	2011
Chemotherapy for second-stage human African trypanosomiasis. The Cochrane database of systematic reviews, 2013, Jun-28, Issue:6 Topics: Animals; Antiprotozoal Agents; Drug Therapy, Combination; Eflornithine; Humans; Melarsoprol; Nifurtimox; Pentamidine; Prednisolone; Randomized Controlled Trials as Topic; Recurrence; Trypanosoma brucei gambiense; Trypanosomiasis, African	2013

Other Studies

27 other study(ies) available for pentamidine and nifurtimox

Article	Year
Design and synthesis of a series of melamine-based nitroheterocycles with activity against Trypanosomatid parasites. Journal of medicinal chemistry, 2005, Aug-25, Volume: 48, Issue:17 Topics: Animals; Cell Line; Female; Furaldehyde; Hydrazones; Leishmania donovani; Mice; Nitrofurans; Nucleoside Transport Proteins; Rats; Thiophenes; Triazines; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense; Trypanosoma cruzi; Trypanosomiasis, African	2005
2H-benzimidazole 1,3-dioxide derivatives: a new family of water-soluble anti-trypanosomatid agents. Journal of medicinal chemistry, 2006, Jun-01, Volume: 49, Issue:11 Topics: Acute Disease; Animals; Benzimidazoles; Cell Line; Chagas Disease; Cyclic N-Oxides; Leishmania; Macrophages; Mice; Mice, Inbred BALB C; Models, Molecular; Oxidation-Reduction; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi	2006
On-bead screening of a combinatorial fumaric acid derived peptide library yields antiplasmodial cysteine protease inhibitors with unusual peptide sequences. Journal of medicinal chemistry, 2009, Sep-24, Volume: 52, Issue:18 Topics: Amino Acid Sequence; Animals; Antiprotozoal Agents; Cathepsin L; Cathepsins; Cattle; Combinatorial Chemistry Techniques; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Diamide; Drug Evaluation, Preclinical; Fumarates; Humans; Peptide Library; Plasmodium falciparum	2009
Synthesis and in vitro activity of limonene derivatives against Leishmania and Trypanosoma. European journal of medicinal chemistry, 2010, Volume: 45, Issue:4 Topics: Animals; Antiprotozoal Agents; Cyclohexenes; In Vitro Techniques; Leishmania; Limonene; Macaca mulatta; Magnetic Resonance Spectroscopy; Mass Spectrometry; Terpenes; Trypanosoma	2010
Michael acceptor based antiplasmodial and antitrypanosomal cysteine protease inhibitors with unusual amino acids. Journal of medicinal chemistry, 2010, Mar-11, Volume: 53, Issue:5 Topics: Antimalarials; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Plasmodium falciparum; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Cross-resistance to nitro drugs and implications for treatment of human African trypanosomiasis. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:7 Topics: Animals; Cell Line; Drug Resistance; Eflornithine; Humans; Mice; Nifurtimox; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	2010
Synthesis and antikinetoplastid activity of a series of N,N'-substituted diamines. Bioorganic & medicinal chemistry letters, 2012, Feb-15, Volume: 22, Issue:4 Topics: Animals; Antiprotozoal Agents; Chagas Disease; Diamines; Humans; Inhibitory Concentration 50; Kinetoplastida; Leishmaniasis, Visceral; Molecular Structure; Small Molecule Libraries; Trypanosomiasis, African	2012
A class of 5-nitro-2-furancarboxylamides with potent trypanocidal activity against Trypanosoma brucei in vitro. Journal of medicinal chemistry, 2013, Feb-14, Volume: 56, Issue:3 Topics: Amides; Animals; HeLa Cells; Humans; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei	2013
Highly improved antiparasitic activity after introduction of an N-benzylimidazole moiety on protein farnesyltransferase inhibitors. European journal of medicinal chemistry, 2016, Feb-15, Volume: 109 Topics: Alkyl and Aryl Transferases; Animals; Antiparasitic Agents; Cell Line; Enzyme Inhibitors; Humans; Imidazoles; Leishmania donovani; Leishmaniasis, Visceral; Malaria, Falciparum; Mice; Parasitic Sensitivity Tests; Plasmodium falciparum; Trypanosoma; Trypanosoma brucei brucei; Trypanosoma cruzi; Trypanosomiasis	2016
Profiling of Flavonol Derivatives for the Development of Antitrypanosomatidic Drugs. Journal of medicinal chemistry, 2016, 08-25, Volume: 59, Issue:16 Topics: Animals; Biological Products; Cell Line; Dose-Response Relationship, Drug; Flavonols; Humans; Macrophages; Mice; Mice, Inbred BALB C; Models, Molecular; Molecular Structure; Parasitic Sensitivity Tests; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei	2016
Targeting the HSP60/10 chaperonin systems of Trypanosoma brucei as a strategy for treating African sleeping sickness. Bioorganic & medicinal chemistry letters, 2016, 11-01, Volume: 26, Issue:21 Topics: Animals; Antiprotozoal Agents; Chaperonin 10; Chaperonin 60; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Humans; Trypanosoma brucei brucei; Trypanosomiasis, African	2016
Methoxylated 2'-hydroxychalcones as antiparasitic hit compounds. European journal of medicinal chemistry, 2017, Jan-27, Volume: 126 Topics: Animals; Antiparasitic Agents; Cell Line, Tumor; Chalcones; Cyclodextrins; Drug Carriers; Mice; Solubility; Trypanosomatina	2017
Synthesis, in vitro and in vivo giardicidal activity of nitrothiazole-NSAID chimeras displaying broad antiprotozoal spectrum. Bioorganic & medicinal chemistry letters, 2017, 08-01, Volume: 27, Issue:15 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antiprotozoal Agents; Drug Design; Female; Giardia lamblia; Giardiasis; Humans; Leishmania; Mice; Nitro Compounds; Protozoan Infections; Thiazoles; Trichomonas vaginalis; Trypanosoma cruzi	2017
2 H-1,2,3-Triazole-Based Dipeptidyl Nitriles: Potent, Selective, and Trypanocidal Rhodesain Inhibitors by Structure-Based Design. Journal of medicinal chemistry, 2018, 04-26, Volume: 61, Issue:8 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dipeptides; Drug Design; Female; Humans; Leishmania donovani; Ligands; Mice; Microsomes, Liver; Molecular Structure; Nitriles; Plasmodium falciparum; Protozoan Proteins; Rats; Structure-Activity Relationship; Swine; Triazoles; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2018
Quinoxaline derivatives as potential antitrypanosomal and antileishmanial agents. Bioorganic & medicinal chemistry, 2018, 08-07, Volume: 26, Issue:14 Topics: Antiprotozoal Agents; Dose-Response Relationship, Drug; Leishmania donovani; Molecular Structure; Parasitic Sensitivity Tests; Quinoxalines; Structure-Activity Relationship; Trypanosoma brucei brucei; Trypanosoma cruzi	2018
Nongenotoxic 3-Nitroimidazo[1,2- ACS medicinal chemistry letters, 2019, Jan-10, Volume: 10, Issue:1 Topics:	2019
Thiazolidinone/thiazole based hybrids - New class of antitrypanosomal agents. European journal of medicinal chemistry, 2019, Jul-15, Volume: 174 Topics: Animals; Cell Line; Humans; Inhibitory Concentration 50; Male; Mice; Molecular Structure; Structure-Activity Relationship; Thiazolidines; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei gambiense	2019
Benzophenone Glucosides and B-Type Proanthocyanidin Dimers from Zambian Journal of natural products, 2022, 01-28, Volume: 85, Issue:1 Topics: Benzophenones; Cassia; Crystallography, X-Ray; Dimerization; Glucosides; Molecular Structure; Proanthocyanidins; Proton Magnetic Resonance Spectroscopy; Trypanocidal Agents; Trypanosoma	2022
The effects of some drugs--pentamidine, stibocaptate, Hoechst 33258, F 151, compound 'E' and Nifurtimox--on Onchocerca volvulus in chimpanzees. Tropenmedizin und Parasitologie, 1977, Volume: 28, Issue:4 Topics: Animals; Anthelmintics; Antimony; Arsenicals; Bisbenzimidazole; Female; Male; Nifurtimox; Onchocerca; Onchocerciasis; Organometallic Compounds; Pan troglodytes; Pentamidine; Succimer; Succinates	1977
Drugs for protozoan infections. American family physician, 1987, Volume: 35, Issue:3 Topics: Antimalarials; Antimony Sodium Gluconate; Antiprotozoal Agents; Humans; Iodoquinol; Melarsoprol; Metronidazole; Nifurtimox; Pentamidine; Protozoan Infections; Suramin	1987
Pentamidine movement across the murine blood-brain and blood-cerebrospinal fluid barriers: effect of trypanosome infection, combination therapy, P-glycoprotein, and multidrug resistance-associated protein. The Journal of pharmacology and experimental therapeutics, 2009, Volume: 329, Issue:3 Topics: Adenine; Adenosine; Animals; ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Blood-Brain Barrier; Brain; Cerebrospinal Fluid; Disease Models, Animal; Drug Interactions; Eflornithine; Indomethacin; Male; Melarsoprol; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Mice, Knockout; Multidrug Resistance-Associated Proteins; Nifurtimox; Pentamidine; Perfusion; Suramin; Trypanosoma brucei brucei; Trypanosomiasis, African	2009
Killer coma: the evolving story of sleeping sickness treatment. Lancet (London, England), 2010, Jan-09, Volume: 375, Issue:9709 Topics: Animals; Biomedical Research; Drug Discovery; Drug Resistance; Drug Therapy, Combination; Eflornithine; Humans; Insect Vectors; Nifurtimox; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African; Tsetse Flies; World Health Organization	2010
High-throughput decoding of antitrypanosomal drug efficacy and resistance. Nature, 2012, Jan-25, Volume: 482, Issue:7384 Topics: Aquaglyceroporins; Drug Resistance; Eflornithine; Endocytosis; Glycosylation; High-Throughput Screening Assays; Humans; Lysosomes; Melarsoprol; Nifurtimox; Pentamidine; RNA Interference; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	2012
Evaluation of trypanocidal drugs used for human African trypanosomosis against Trypanosoma lewisi. Parasite (Paris, France), 2013, Volume: 20 Topics: Animals; Eflornithine; Female; Humans; Immunocompromised Host; Inhibitory Concentration 50; Melarsoprol; Mice; Nifurtimox; Nitroimidazoles; Parasitemia; Pentamidine; Rats; Rats, Wistar; Suramin; Trypanocidal Agents; Trypanosoma lewisi; Trypanosomiasis	2013
African sleeping sickness. British journal of hospital medicine (London, England : 2005), 2016, Volume: 77, Issue:10 Topics: Animals; Eflornithine; Humans; Insect Vectors; Nifurtimox; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Tsetse Flies	2016
Insights into antitrypanosomal drug mode-of-action from cytology-based profiling. PLoS neglected tropical diseases, 2018, Volume: 12, Issue:11 Topics: Cell Biology; Humans; Lysosomes; Melarsoprol; Mitochondria; Mitochondrial Proteins; Mitosis; Nifurtimox; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	2018