pentamidine and furamidine

pentamidine has been researched along with furamidine in 43 studies

Research

Studies (43)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (6.98)	18.7374
1990's	3 (6.98)	18.2507
2000's	22 (51.16)	29.6817
2010's	14 (32.56)	24.3611
2020's	1 (2.33)	2.80

Authors

Authors	Studies
Boykin, DW; Das, BP	1
Clercq, ED; Dann, O	1
Bender, BC; Boykin, DW; Hall, JE; Kumar, A; McCurdy, DR; Tidwell, RR; Wilson, WD; Xiao, G	1
Bajic, M; Bender, BC; Boykin, DW; Hall, JE; Hopkins, KT; Kumar, A; McCurdy, DR; Tidwell, RR; Wilson, WD	1
Bender, BC; Boykin, DW; Hall, JE; McCurdy, DR; Rahmathullah, SM; Tidwell, RR	1
Boykin, DW; Brun, R; Salem, MM; Stephens, CE; Tanious, F; Werbovetz, KA; Wilson, WD	1
Boykin, DW; Brun, R; Easterbrook, JD; Ismail, MA; Tanious, FA; Wilson, WD	1
Boykin, DW; Brun, R; Ismail, MA; Tanious, FA; Wenzler, T; Wilson, WD	1
Arafa, RK; Boykin, DW; Brun, R; Stephens, CE; Tanious, FA; Wenzler, T; Wilson, WD	1
Arafa, RK; Boykin, DW; Bridges, A; Brun, R; Generaux, C; Hall, JE; Ismail, MA; Miao, Y; Wenzler, T; Wilson, WD	1
Barszcz, T; Boykin, DW; Brun, R; Gonzalez, JL; Stephens, CE; Tanious, FA; Wenzler, T; Werbovetz, KA; Wilson, WD	1
Boykin, DW; Hall, JE; Jones, SK; Rahmathullah, SM; Tidwell, RR	1
Brun, R; de Koning, HP; Gould, M; Kaiser, M; Koomen, GJ; Rodenko, B; van der Burg, AM; Wanner, MJ	1
Bakunov, SA; Bakunova, SM; Barzcz, T; Brun, R; Chen, H; Jones, SK; Kumar, EV; Patrick, DA; Tidwell, RR; Wenzler, T; Werbovetz, KA	1
Boykin, DW; Brun, R; Hall, JE; Ismail, MA; Tidwell, RR; Wenzler, T	1
Arafa, RK; Boykin, DW; Brun, R; Hu, L; Ismail, MA; Munde, M; Patel, A; Wenzler, T; Wilson, WD	1
Barghash, Ael-D; Boykin, DW; Brun, R; Eisa, HM; Farahat, AA; Goda, FE; Kumar, A; Liu, Y; Mickelson, L; Say, M; Wenzler, T; Wilson, WD	1
Maciejewska, D; Zołek, T	1
Boykin, DW; Branowska, D; Brun, R; Farahat, AA; Kumar, A; Liu, Y; Wenzler, T; Wilson, WD	1
Bialy, SA; Boykin, DW; Brun, R; Ismail, MA; Nanjunda, R; Wenzler, T; Wilson, WD	1
Barghash, AE; Boykin, DW; Brun, R; Eisa, HM; Farahat, AA; Goda, FE; Kumar, A; Liu, Y; Paliakov, E; Wenzler, T; Wilson, WD	1
Arafa, RK; Boykin, DW; Brun, R; Ismail, MA; Jones, SK; Pandharkar, T; Patrick, DA; Tidwell, RR; Wenzler, T; Werbovetz, KA; Zhu, X	1
Bakunov, SA; Bakunova, SM; Barszcz, T; Boykin, DW; Brun, R; Jones, SK; Kumar, A; Patrick, DA; Tidwell, RR; Wenzler, T; Werbovetz, KA	1
Bondada, L; Boykin, DW; Brun, R; Hu, L; Munde, M; Patel, A; Wang, MZ; Wenzler, T; Wilson, WD; Yang, S	1
Bakunov, SA; Bakunova, SM; Brun, R; Patrick, DA; Tidwell, RR; Wenzler, T	1
He, M; Ivanov, I; Jassim, BA; Qian, K; Yan, C; Zhang, J; Zheng, YG	1
Davidson, DE; Duxbury, RE; Johnson, AJ; Kinnamon, KE; Masters, RE; Steck, EA	1
Bielawska, A; Bielawski, K	1
Lanteri, CA; Meshnick, SR; Tidwell, RR; Trumpower, BL	1
Bailly, C; Boykin, DW; Kumar, A; Lee, MP; Mallena, S; Neidle, S; Wilson, WD	1
Werbovetz, K	1
Araújo-Jorge, TC; Boykin, DW; De Souza, EM; Hu, Q; Kumar, A; Menna-Barreto, R; Soeiro, MN	1
Boykin, DW; Hall, JE; Holman, JL; Ismail, MA; Mathis, AM; Sturk, LM; Tidwell, RR	1
Agama, KK; Antony, S; Fisher, RJ; Marchand, C; Pommier, Y; Stephen, AG; Thibaut, L	1
Bernhard, SC; Brun, R; Mäser, P; Nerima, B	1
Boykin, DW; Kumar, A; Liu, Y; Wilson, WD	1
Brun, R; Kagira, JM; Karanja, SM; Mdachi, RE; Ngotho, JM; Thuita, JK; Tidwell, R; Wenzler, T	1
Hall, JE; Ju, W; Ming, X; Thakker, DR; Tidwell, RR; Wu, H	1
Generaux, CN; Goldsmith, RB; Gray, DR; Reisner, HM; Tidwell, RR; Yan, Z	1
Barrett, MP; Burchmore, RJ; de Koning, HP; Ward, CP; Wong, PE	1
Boykin, DW; Brun, R; Miller, PN; Wang, MZ; Wenzler, T; Wu, H; Yang, S	1
Choi, G; No, JH; Yang, G	1
Barygin, OI; Zhigulin, AS	1

Reviews

1 review(s) available for pentamidine and furamidine

Article	Year
Diamidines as antitrypanosomal, antileishmanial and antimalarial agents. Current opinion in investigational drugs (London, England : 2000), 2006, Volume: 7, Issue:2 Topics: Animals; Antimalarials; Antiprotozoal Agents; Benzamidines; Chagas Disease; Clinical Trials as Topic; Drug Evaluation, Preclinical; Humans; Leishmania; Leishmaniasis; Malaria, Falciparum; Pentamidine; Plasmodium falciparum; Prodrugs; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosoma cruzi; Trypanosomiasis, African	2006

Article

Year

Diamidines as antitrypanosomal, antileishmanial and antimalarial agents.

Current opinion in investigational drugs (London, England : 2000), 2006, Volume: 7, Issue:2

Topics: Animals; Antimalarials; Antiprotozoal Agents; Benzamidines; Chagas Disease; Clinical Trials as Topic; Drug Evaluation, Preclinical; Humans; Leishmania; Leishmaniasis; Malaria, Falciparum; Pentamidine; Plasmodium falciparum; Prodrugs; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosoma cruzi; Trypanosomiasis, African

2006

Other Studies

42 other study(ies) available for pentamidine and furamidine

Article	Year
Synthesis and antiprotozoal activity of 2,5-bis(4-guanylphenyl)thiophenes and -pyrroles. Journal of medicinal chemistry, 1977, Volume: 20, Issue:9 Topics: Amidines; Animals; Antiprotozoal Agents; Mice; Plasmodium berghei; Pyrroles; Structure-Activity Relationship; Thiophenes; Trypanosoma	1977
Diaryl amidine derivatives as oncornaviral DNA polymerase inhibitors. Journal of medicinal chemistry, 1980, Volume: 23, Issue:7 Topics: Amidines; Animals; Antineoplastic Agents; Kinetics; Leukemia, Experimental; Mice; Moloney murine leukemia virus; Retroviridae; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Tilorone	1980
2,5-bis[4-(N-alkylamidino)phenyl]furans as anti-Pneumocystis carinii agents. Journal of medicinal chemistry, 1998, Jan-01, Volume: 41, Issue:1 Topics: Animals; Anti-Infective Agents; Base Sequence; Binding Sites; Furans; Microchemistry; Oligodeoxyribonucleotides; Pneumocystis; Pneumonia, Pneumocystis; Poly dA-dT; Rats	1998
Extended aromatic furan amidino derivatives as anti-Pneumocystis carinii agents. Journal of medicinal chemistry, 1998, Sep-24, Volume: 41, Issue:20 Topics: Amidines; Animals; Antifungal Agents; Drug Evaluation, Preclinical; Furans; Immunosuppression Therapy; Oligodeoxyribonucleotides; Pneumonia, Pneumocystis; Poly dA-dT; Protein Binding; Rats; Structure-Activity Relationship	1998
Prodrugs for amidines: synthesis and anti-Pneumocystis carinii activity of carbamates of 2,5-bis(4-amidinophenyl)furan. Journal of medicinal chemistry, 1999, Sep-23, Volume: 42, Issue:19 Topics: Administration, Oral; Animals; Antifungal Agents; Benzamidines; Carbamates; Models, Chemical; Pneumocystis; Prodrugs; Rats	1999
The activity of diguanidino and 'reversed' diamidino 2,5-diarylfurans versus Trypanosoma cruzi and Leishmania donovani. Bioorganic & medicinal chemistry letters, 2003, Jun-16, Volume: 13, Issue:12 Topics: Amidines; Animals; DNA; Furans; Guanidine; Inhibitory Concentration 50; Leishmania donovani; Macrophages; Nucleic Acid Denaturation; Oligodeoxyribonucleotides; Poly dA-dT; Protozoan Proteins; Structure-Activity Relationship; Temperature; Trypanocidal Agents; Trypanosoma cruzi	2003
Synthesis and antiprotozoal activity of aza-analogues of furamidine. Journal of medicinal chemistry, 2003, Oct-23, Volume: 46, Issue:22 Topics: Animals; Antimalarials; Antiprotozoal Agents; Aza Compounds; Benzamidines; Mice; Plasmodium falciparum; Prodrugs; Structure-Activity Relationship; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	2003
Novel dicationic imidazo[1,2-a]pyridines and 5,6,7,8-tetrahydro-imidazo[1,2-a]pyridines as antiprotozoal agents. Journal of medicinal chemistry, 2004, Jul-01, Volume: 47, Issue:14 Topics: Animals; Antimalarials; Antiprotozoal Agents; Imidazoles; Mice; Plasmodium falciparum; Pyridines; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei rhodesiense	2004
Synthesis, DNA affinity, and antiprotozoal activity of fused ring dicationic compounds and their prodrugs. Journal of medicinal chemistry, 2005, Aug-25, Volume: 48, Issue:17 Topics: Animals; Antiprotozoal Agents; Carbamates; Cations; Circular Dichroism; DNA; Fluorenes; Guanidines; Mice; Plasmodium falciparum; Poly dA-dT; Prodrugs; Structure-Activity Relationship; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	2005
Synthesis, DNA affinity, and antiprotozoal activity of linear dications: Terphenyl diamidines and analogues. Journal of medicinal chemistry, 2006, Aug-24, Volume: 49, Issue:17 Topics: Administration, Oral; Animals; Antiprotozoal Agents; Biotransformation; Cations; DNA; Drug Stability; In Vitro Techniques; Liver; Mice; Microsomes; Molecular Structure; Parasitic Sensitivity Tests; Pentamidine; Plasmodium falciparum; Prodrugs; Stereoisomerism; Structure-Activity Relationship; Terphenyl Compounds; Trypanosoma brucei rhodesiense	2006
Synthesis and antiparasitic evaluation of bis-2,5-[4-guanidinophenyl]thiophenes. European journal of medicinal chemistry, 2007, Volume: 42, Issue:4 Topics: Animals; Antiparasitic Agents; Disease Models, Animal; Guanidines; Leishmania; Mice; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium; Thiophenes; Trypanosoma	2007
Carbamate prodrugs of N-alkylfuramidines. European journal of medicinal chemistry, 2008, Volume: 43, Issue:1 Topics: Animals; Benzamidines; Carbamates; Cysts; Disease Models, Animal; Furans; Lung; Pneumocystis carinii; Pneumonia, Pneumocystis; Prodrugs; Rats	2008
2,N6-disubstituted adenosine analogs with antitrypanosomal and antimalarial activities. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:11 Topics: Adenosine; Animals; Antimalarials; Dose-Response Relationship, Drug; Molecular Structure; Plasmodium falciparum; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma cruzi	2007
Synthesis and antiprotozoal activities of dicationic bis(phenoxymethyl)benzenes, bis(phenoxymethyl)naphthalenes, and bis(benzyloxy)naphthalenes. European journal of medicinal chemistry, 2009, Volume: 44, Issue:9 Topics: Animals; Antiprotozoal Agents; Benzene; Cell Survival; Leishmania donovani; Mice; Myoblasts; Naphthalenes; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Structure-Activity Relationship; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	2009
New treatment option for second-stage African sleeping sickness: in vitro and in vivo efficacy of aza analogs of DB289. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:10 Topics: Animals; Benzamidines; Central Nervous System; Female; Furans; Mice; Molecular Structure; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei gambiense; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	2009
Synthesis and activity of azaterphenyl diamidines against Trypanosoma brucei rhodesiense and Plasmodium falciparum. Bioorganic & medicinal chemistry, 2009, Sep-15, Volume: 17, Issue:18 Topics: Animals; Antiprotozoal Agents; Inhibitory Concentration 50; Malaria, Falciparum; Mice; Parasitic Sensitivity Tests; Pentamidine; Plasmodium falciparum; Structure-Activity Relationship; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	2009
Synthesis, DNA binding, fluorescence measurements and antiparasitic activity of DAPI related diamidines. Bioorganic & medicinal chemistry, 2010, Jan-15, Volume: 18, Issue:2 Topics: Animals; Apoptosis; Binding Sites; Cells, Cultured; DNA, Protozoan; Drug Evaluation, Preclinical; Fluorescence; Indoles; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Trypanosoma brucei rhodesiense	2010
Theoretical models of pentamidine analogs activity based on their DNA minor groove complexes. European journal of medicinal chemistry, 2010, Volume: 45, Issue:5 Topics: Binding Sites; DNA; Models, Chemical; Models, Molecular; Molecular Dynamics Simulation; Molecular Structure; Nucleic Acid Denaturation; Pentamidine; Spectrophotometry, Ultraviolet; Stereoisomerism; Temperature	2010
Synthesis and antiprotozoal activity of 2,5-bis[amidinoaryl]thiazoles. Bioorganic & medicinal chemistry, 2010, May-15, Volume: 18, Issue:10 Topics: Administration, Oral; Animals; Antimalarials; Antiprotozoal Agents; Disease Models, Animal; DNA, Protozoan; Drug Stability; Malaria, Falciparum; Mice; Parasitic Sensitivity Tests; Pentamidine; Plasmodium falciparum; Rats; Stereoisomerism; Structure-Activity Relationship; Thiazoles; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	2010
Dicationic phenyl-2,2'-bichalcophenes and analogues as antiprotozoal agents. Bioorganic & medicinal chemistry, 2011, Jan-15, Volume: 19, Issue:2 Topics: Animals; Antiprotozoal Agents; Disease Models, Animal; Mice; Pentamidine; Plasmodium falciparum; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	2011
Exploration of larger central ring linkers in furamidine analogues: synthesis and evaluation of their DNA binding, antiparasitic and fluorescence properties. Bioorganic & medicinal chemistry, 2011, Apr-01, Volume: 19, Issue:7 Topics: Animals; Antiparasitic Agents; Antiprotozoal Agents; Benzamidines; Benzimidazoles; Circular Dichroism; Cross-Linking Reagents; DNA, Protozoan; Fluorescence; Humans; Mice; Models, Chemical; Molecular Structure; Plasmodium falciparum; Structure-Activity Relationship; Trypanosoma brucei rhodesiense	2011
Synthesis and antiprotozoal activity of dicationic m-terphenyl and 1,3-dipyridylbenzene derivatives. Journal of medicinal chemistry, 2013, Jul-11, Volume: 56, Issue:13 Topics: Animals; Antiprotozoal Agents; Benzene; Chagas Disease; Female; Leishmania donovani; Mice; Mice, Inbred Strains; Models, Chemical; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyridines; Structure-Activity Relationship; Terphenyl Compounds; Trypanosoma cruzi	2013
Synthesis and antiprotozoal activities of benzyl phenyl ether diamidine derivatives. European journal of medicinal chemistry, 2013, Volume: 67 Topics: Animals; Antiprotozoal Agents; Dose-Response Relationship, Drug; Leishmania donovani; Mice; Molecular Structure; Myoblasts; Parasitic Sensitivity Tests; Pentamidine; Phenyl Ethers; Plasmodium falciparum; Rats; Structure-Activity Relationship; Trypanosoma brucei rhodesiense; Trypanosomiasis	2013
Synthesis and antiprotozoal activity of dicationic 2,6-diphenylpyrazines and aza-analogues. Bioorganic & medicinal chemistry, 2013, Nov-01, Volume: 21, Issue:21 Topics: Animals; Antiprotozoal Agents; Aza Compounds; Cations; Cell Line; Cell Survival; Disease Models, Animal; Mice; Myoblasts; Parasitic Sensitivity Tests; Pentamidine; Plasmodium falciparum; Poly dA-dT; Prodrugs; Pyrazines; Rats; Structure-Activity Relationship; Transition Temperature; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	2013
Antiprotozoal activity of dicationic 3,5-diphenylisoxazoles, their prodrugs and aza-analogues. Bioorganic & medicinal chemistry, 2014, Jan-01, Volume: 22, Issue:1 Topics: Animals; Antiprotozoal Agents; Isoxazoles; Mice; Molecular Structure; Plasmodium falciparum; Prodrugs; Structure-Activity Relationship; Trypanosomiasis, African	2014
Discovery of Decamidine as a New and Potent PRMT1 Inhibitor. MedChemComm, 2017, Feb-01, Volume: 8, Issue:2 Topics:	2017
Trypanosoma rhodesiense: evaluation of the antitrypanosomal action of 2,5-bis(4-guanylphenyl)furan dihydrochloride. Experimental parasitology, 1982, Volume: 53, Issue:1 Topics: Amidines; Animals; Benzamidines; Female; Macaca mulatta; Male; Pentamidine; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	1982
Molecular modelling of the interaction of pentamidine analogues with d(CGCGAATTCGCG)2 duplex. Roczniki Akademii Medycznej w Bialymstoku (1995), 2000, Volume: 45 Topics: Benzamidines; DNA; Energy Metabolism; Models, Molecular; Pentamidine; Structure-Activity Relationship	2000
DB75, a novel trypanocidal agent, disrupts mitochondrial function in Saccharomyces cerevisiae. Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:10 Topics: Antifungal Agents; Benzamidines; Culture Media; Glycerol; Intracellular Membranes; Membrane Potentials; Microscopy, Fluorescence; Mitochondria; Oxygen Consumption; Pentamidine; Saccharomyces cerevisiae; Trypanocidal Agents	2004
Thiophene-based diamidine forms a "super" at binding minor groove agent. Journal of the American Chemical Society, 2004, Oct-27, Volume: 126, Issue:42 Topics: Adenine; Animals; Base Pairing; Benzamidines; Biosensing Techniques; Calorimetry; Cattle; Chemical Phenomena; Chemistry, Physical; Circular Dichroism; Crystallography, X-Ray; Deoxyribonuclease I; DNA; DNA Footprinting; Models, Molecular; Nucleic Acid Conformation; Pentamidine; Surface Plasmon Resonance; Thermodynamics; Thiophenes; Thymine; Titrimetry	2004
Antiparasitic activity of aromatic diamidines is related to apoptosis-like death in Trypanosoma cruzi. Parasitology, 2006, Volume: 133, Issue:Pt 1 Topics: Animals; Apoptosis; Benzamidines; DNA Fragmentation; Dose-Response Relationship, Drug; Flow Cytometry; Mice; Parasitic Sensitivity Tests; Pentamidine; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi	2006
Accumulation and intracellular distribution of antitrypanosomal diamidine compounds DB75 and DB820 in African trypanosomes. Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:6 Topics: Animals; Benzamidines; Cell Nucleus; Cytoplasm; Dose-Response Relationship, Drug; Fluorescence; Furans; In Vitro Techniques; Kinetics; Male; Mice; Molecular Structure; Organelles; Pentamidine; Tissue Distribution; Trypanocidal Agents; Trypanosoma brucei gambiense	2006
Novel high-throughput electrochemiluminescent assay for identification of human tyrosyl-DNA phosphodiesterase (Tdp1) inhibitors and characterization of furamidine (NSC 305831) as an inhibitor of Tdp1. Nucleic acids research, 2007, Volume: 35, Issue:13 Topics: Antineoplastic Agents; Benzamidines; Diminazene; DNA; DNA, Single-Stranded; Drug Evaluation, Preclinical; Electrochemistry; Humans; Kinetics; Luminescent Measurements; Pentamidine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Thymidine	2007
Melarsoprol- and pentamidine-resistant Trypanosoma brucei rhodesiense populations and their cross-resistance. International journal for parasitology, 2007, Volume: 37, Issue:13 Topics: Animals; Antifungal Agents; Benzamidines; Drug Resistance; Female; Melarsoprol; Mice; Parasitic Sensitivity Tests; Pentamidine; Trypanocidal Agents; Trypanosoma brucei rhodesiense	2007
Sequence and length dependent thermodynamic differences in heterocyclic diamidine interactions at AT base pairs in the DNA minor groove. Biophysical chemistry, 2007, Volume: 131, Issue:1-3 Topics: Antiparasitic Agents; Base Sequence; Benzamidines; Calorimetry, Differential Scanning; Circular Dichroism; DNA; Pentamidine; Poly dA-dT; Thermodynamics; Ultraviolet Rays	2007
Efficacy of the diamidine DB75 and its prodrug DB289, against murine models of human African trypanosomiasis. Acta tropica, 2008, Volume: 108, Issue:1 Topics: Administration, Oral; Animals; Antiprotozoal Agents; Benzamidines; Female; Humans; Mice; Molecular Structure; Pentamidine; Prodrugs; Trypanosoma brucei gambiense; Trypanosomiasis, African	2008
Transport of dicationic drugs pentamidine and furamidine by human organic cation transporters. Drug metabolism and disposition: the biological fate of chemicals, 2009, Volume: 37, Issue:2 Topics: Antifungal Agents; Benzamidines; Biological Transport; Cations; Female; Glucuronides; Humans; Organic Cation Transport Proteins; Organic Cation Transporter 1; Pentamidine	2009
Application of monoclonal antibodies to measure metabolism of an anti-trypanosomal compound in vitro and in vivo. Journal of clinical laboratory analysis, 2010, Volume: 24, Issue:3 Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Benzamidines; Cross Reactions; Enzyme-Linked Immunosorbent Assay; Female; Hepatocytes; Humans; Immunoglobulin G; Male; Mice; Mice, Inbred BALB C; Pentamidine; Prodrugs; Rats; Rats, Sprague-Dawley; Rats, Wistar; Tandem Mass Spectrometry; Trypanocidal Agents; Trypanosomiasis, African	2010
Trypanocidal furamidine analogues: influence of pyridine nitrogens on trypanocidal activity, transport kinetics, and resistance patterns. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:5 Topics: Adenine; Animals; Benzamidines; Biological Transport; Drug Resistance; Female; Nitrogen; Pentamidine; Pyridines; Rats; Trypanocidal Agents	2011
Pharmacokinetic comparison to determine the mechanisms underlying the differential efficacies of cationic diamidines against first- and second-stage human African trypanosomiasis. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:7 Topics: Amidines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzamidines; Blood-Brain Barrier; Cell Line; Dogs; Furans; Madin Darby Canine Kidney Cells; Male; Mice; Pentamidine; Protein Binding; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	2014
Antileishmanial Mechanism of Diamidines Involves Targeting Kinetoplasts. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:11 Topics: Amidines; Benzamidines; DNA Replication; DNA Topoisomerases, Type II; DNA-Binding Proteins; DNA, Kinetoplast; DNA, Mitochondrial; Drug Evaluation, Preclinical; Fluorescence; Leishmania donovani; Molecular Targeted Therapy; Pentamidine; Protozoan Proteins; Topoisomerase II Inhibitors; Trypanocidal Agents	2016
Mechanisms of NMDA Receptor Inhibition by Sepimostat-Comparison with Nafamostat and Diarylamidine Compounds. International journal of molecular sciences, 2023, Oct-27, Volume: 24, Issue:21 Topics: Animals; Cells, Cultured; Guanidines; Hippocampus; N-Methylaspartate; Pentamidine; Rats; Receptors, N-Methyl-D-Aspartate	2023