pentamidine and eflornithine

pentamidine has been researched along with eflornithine in 49 studies

Research

Studies (49)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (6.12)	18.7374
1990's	13 (26.53)	18.2507
2000's	12 (24.49)	29.6817
2010's	21 (42.86)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Ishiyama, A; Kinoshita, E; Kitajima, M; Kogure, N; Omura, S; Otoguro, K; Takayama, H; Toriizuka, Y; Yamada, H	1
Büchold, C; Gelhaus, C; Gut, J; Kisker, C; Leippe, M; Leyh, M; Machon, U; Rosenthal, PJ; Schirmeister, T; Schmuck, C; Stempka, M	1
Breuning, A; Büchold, C; Degel, B; Gelhaus, C; Gut, J; Heppner, S; Kisker, C; Leippe, M; Leyh, M; Machon, U; Rath, J; Rosenthal, PJ; Schirmeister, T; Schmuck, C; Schulz, F; Stempka, M; Stich, A	1
Fairlamb, AH; Oza, SL; Patterson, S; Read, KD; Sokolova, AY; Wyllie, S	1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A	1
Clayton, C; De Muylder, G; Gerwick, L; Helbig, C; Knudsen, GM; Linington, RG; Mackey, ZB; Mascuch, SM; McKerrow, JH; Sanchez, LM	1
Behera, R; Edwards, P; Guyett, PJ; Karver, CE; Mensa-Wilmot, K; Patel, G; Pollastri, MP; Roncal, NE; Sullenberger, C	1
Aoyagi, Y; Fujiwara, K; Fukaya, H; Hitotsuyanagi, Y; Ishiyama, A; Iwatsuki, M; Ōmura, S; Otoguro, K; Sugawara, N; Takeya, K; Yamada, H; Yamazaki, A; Yano, R	1
Bharate, SB; Jain, SK; Khan, IA; Khan, SI; Manda, S; Mohammed, S; Tekwani, BL; Vishwakarma, RA	1
Abdeen, S; Chapman, E; Goldsmith-Pestana, K; Horwich, AL; Johnson, SM; Mammadova, N; McMahon-Pratt, D; Salim, N; Schultz, PG; Summers, CM	1
Brun, R; Diederich, F; Giroud, M; Haap, W; Kaiser, M; Kuhn, B; Kuratli, C; Martin, RE; Saint-Auret, S; Schirmeister, T; Schuler, F	1
Jennings, FW	1
Feinberg, J; Sattler, FR	1
Girard, PM; Saimot, AG	1
Kovacs, JA; Lipschik, GY; Masur, H	1
Davies, S; Gazzard, B; Gleeson, J; Nelson, M; Smith, D; Youle, M	1
Hauptman, SP; Wordell, CJ	1
Catterall, JR; Potasman, I; Remington, JS	1
Cushion, MT; Linke, MJ; Stanforth, D; Walzer, PD	1
Boa Yapo, F; Doua, F	1
Doua, F; Yapo, FB	1
Milord, F; Pépin, J	1
Ewig, S; Lüderitz, B; Rockstroh, JK; Schäfer, H	1
Badet-Denisot, MA; Basselin, M; Lawrence, F; Robert-Gero, M	1
Cattand, P; Jannin, J	1
Bamba, M; Coulibaly, S; Doua, F; Miezan, TB; Youan, BB	1
Fishman, JA	1
Barrett, MP; Barrett, SV	1
de Koning, HP	1
Maloba, B; Nagar, S; Popara, M; Smego, RA	1
Etchegorry, MG; Helenport, JP; Jannin, J; Legros, D; Pecoul, B	1
Kager, PA	1
Docampo, R; Moreno, SN	1
Abel, PM; Behrend, M; Fleischmann, H; Kiala, G; Krishna, S; Lôa, V; Musolf, J; Stich, A; Théophile, J	1
Balasegaram, M; Checchi, F; Hamel, C; Harris, S; Karunakara, U	1
De Koning, HP; Dogruel, M; Rodgers, J; Sanderson, L; Thomas, SA	1
Blum, J; Brun, R; Burri, C; Chappuis, F	1
Schlitzer, M	1
Boelaert, M; Büscher, P; Lejon, V; Ngoyi, DM	1
Kennedy, A; Lutje, V; Seixas, J	2
Barrett, MP	1
Barrett, MP; Burchmore, RJ; Kazibwe, AJ; Matovu, E; Vincent, IM	1
Josenando, T; Lando, A; Penchenier, L; Truc, P; Vatunga, G	1
Alsford, S; Baker, N; Berriman, M; Eckert, S; Field, MC; Glover, L; Horn, D; Leung, KF; Sanchez-Flores, A; Turner, DJ	1
Bucheton, B; Courtois, P; Cuny, G; Daulouède, S; Dethoua, M; Nzoumbou-Boko, R; Semballa, S; Truc, P; Vincendeau, P	1
Chiodini, PL; Fink, D; Hedley, L; Sparkes, D	1
Khan, IA; Khan, SI; Mahajan, S; Singh, IP; Tekwani, BL	1

Reviews

12 review(s) available for pentamidine and eflornithine

Article	Year
[Pneumocystis carinii pneumonia in HIV infection. Diagnosis, prognostic factors and curative treatment]. Presse medicale (Paris, France : 1983), 1991, Feb-16, Volume: 20, Issue:6 Topics: Adrenal Cortex Hormones; Antineoplastic Agents; CD4-Positive T-Lymphocytes; Dapsone; Eflornithine; Folic Acid Antagonists; HIV Infections; Humans; Pentamidine; Pneumonia, Pneumocystis; Prognosis; Quinazolines; Trimethoprim, Sulfamethoxazole Drug Combination; Trimetrexate	1991
Human trypanosomiasis in the Ivory Coast: therapy and problems. Acta tropica, 1993, Volume: 54, Issue:3-4 Topics: Animals; Cote d'Ivoire; Eflornithine; Humans; Melarsoprol; Pentamidine; Recurrence; Trypanosoma brucei gambiense; Trypanosomiasis, African	1993
The treatment of human African trypanosomiasis. Advances in parasitology, 1994, Volume: 33 Topics: Animals; Diminazene; Eflornithine; Humans; Melarsoprol; Nifurtimox; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	1994
Treatment of infection due to Pneumocystis carinii. Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:6 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Atovaquone; Clindamycin; Dapsone; Eflornithine; Humans; Macrolides; Naphthoquinones; Pentamidine; Pneumocystis; Pneumocystis Infections; Pneumonia, Pneumocystis; Pyrimidines; Trimethoprim, Sulfamethoxazole Drug Combination; Trimetrexate	1998
Transporters in African trypanosomes: role in drug action and resistance. International journal for parasitology, 2001, May-01, Volume: 31, Issue:5-6 Topics: Africa South of the Sahara; Animals; Arsenicals; Biological Transport; Eflornithine; Humans; Nitroimidazoles; Pentamidine; Phenanthridines; Suramin; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African	2001
A meta-analysis of salvage therapy for Pneumocystis carinii pneumonia. Archives of internal medicine, 2001, Jun-25, Volume: 161, Issue:12 Topics: Adolescent; Adult; Aged; AIDS-Related Opportunistic Infections; Child; Child, Preschool; Clindamycin; Drug Therapy, Combination; Eflornithine; Female; Humans; Male; Middle Aged; Pentamidine; Pneumonia, Pneumocystis; Prognosis; Salvage Therapy; Survival Rate; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination; Trimetrexate	2001
Current chemotherapy of human African trypanosomiasis. Parasitology research, 2003, Volume: 90 Supp 1 Topics: Animals; Eflornithine; Humans; Melarsoprol; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African	2003
[Agents for the treatment of African sleeping sickness. Those developed in the last century]. Pharmazie in unserer Zeit, 2009, Volume: 38, Issue:6 Topics: Animals; Eflornithine; History, 20th Century; Humans; Melarsoprol; Nifurtimox; Pentamidine; Suramin; Trypanocidal Agents; Trypanosomiasis, African	2009
Chemotherapy for second-stage Human African trypanosomiasis. The Cochrane database of systematic reviews, 2010, Aug-04, Issue:8 Topics: Animals; Antiprotozoal Agents; Drug Therapy, Combination; Eflornithine; Humans; Melarsoprol; Nifurtimox; Pentamidine; Prednisolone; Randomized Controlled Trials as Topic; Recurrence; Trypanosoma brucei gambiense; Trypanosomiasis, African	2010
Potential new drugs for human African trypanosomiasis: some progress at last. Current opinion in infectious diseases, 2010, Volume: 23, Issue:6 Topics: Animals; Benzamides; Boron Compounds; Drug Discovery; Drug Resistance; Drug Therapy, Combination; Eflornithine; Humans; Melarsoprol; Mice; Nifurtimox; Nitroimidazoles; Pentamidine; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	2010
Drug resistance in human African trypanosomiasis. Future microbiology, 2011, Volume: 6, Issue:9 Topics: Animals; Drug Resistance; Eflornithine; Humans; Membrane Transport Proteins; Nifurtimox; Pentamidine; Protozoan Proteins; Treatment Failure; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African	2011
Chemotherapy for second-stage human African trypanosomiasis. The Cochrane database of systematic reviews, 2013, Jun-28, Issue:6 Topics: Animals; Antiprotozoal Agents; Drug Therapy, Combination; Eflornithine; Humans; Melarsoprol; Nifurtimox; Pentamidine; Prednisolone; Randomized Controlled Trials as Topic; Recurrence; Trypanosoma brucei gambiense; Trypanosomiasis, African	2013

Trials

2 trial(s) available for pentamidine and eflornithine

Article	Year
Pneumocystis carinii pneumonia in the patient with AIDS. Chest, 1985, Volume: 88, Issue:5 Topics: Acquired Immunodeficiency Syndrome; Animals; Bronchoscopy; Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Therapy, Combination; Eflornithine; Humans; Male; Ornithine; Pentamidine; Pneumocystis; Pneumonia, Pneumocystis; Pyrimethamine; Sulfadiazine; Sulfamethoxazole; Therapeutic Irrigation; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination	1985
A CATT negative result after treatment for human African trypanosomiasis is no indication for cure. PLoS neglected tropical diseases, 2010, Jan-26, Volume: 4, Issue:1 Topics: Agglutination Tests; Antibodies, Protozoan; Eflornithine; Humans; Melarsoprol; Pentamidine; Treatment Outcome; Trypanocidal Agents; Trypanosomiasis, African	2010

Article

Year

Pneumocystis carinii pneumonia in the patient with AIDS.

Chest, 1985, Volume: 88, Issue:5

Topics: Acquired Immunodeficiency Syndrome; Animals; Bronchoscopy; Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Therapy, Combination; Eflornithine; Humans; Male; Ornithine; Pentamidine; Pneumocystis; Pneumonia, Pneumocystis; Pyrimethamine; Sulfadiazine; Sulfamethoxazole; Therapeutic Irrigation; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1985

A CATT negative result after treatment for human African trypanosomiasis is no indication for cure.

PLoS neglected tropical diseases, 2010, Jan-26, Volume: 4, Issue:1

Topics: Agglutination Tests; Antibodies, Protozoan; Eflornithine; Humans; Melarsoprol; Pentamidine; Treatment Outcome; Trypanocidal Agents; Trypanosomiasis, African

2010

Other Studies

35 other study(ies) available for pentamidine and eflornithine

Article	Year
New lycorine-type alkaloid from Lycoris traubii and evaluation of antitrypanosomal and antimalarial activities of lycorine derivatives. Bioorganic & medicinal chemistry, 2008, Dec-15, Volume: 16, Issue:24 Topics: Alkaloids; Amaryllidaceae Alkaloids; Animals; Antimalarials; Inhibitory Concentration 50; Liliaceae; Parasitic Sensitivity Tests; Phenanthridines; Plasmodium falciparum; Trypanocidal Agents	2008
On-bead screening of a combinatorial fumaric acid derived peptide library yields antiplasmodial cysteine protease inhibitors with unusual peptide sequences. Journal of medicinal chemistry, 2009, Sep-24, Volume: 52, Issue:18 Topics: Amino Acid Sequence; Animals; Antiprotozoal Agents; Cathepsin L; Cathepsins; Cattle; Combinatorial Chemistry Techniques; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Diamide; Drug Evaluation, Preclinical; Fumarates; Humans; Peptide Library; Plasmodium falciparum	2009
Michael acceptor based antiplasmodial and antitrypanosomal cysteine protease inhibitors with unusual amino acids. Journal of medicinal chemistry, 2010, Mar-11, Volume: 53, Issue:5 Topics: Antimalarials; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Plasmodium falciparum; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei	2010
Cross-resistance to nitro drugs and implications for treatment of human African trypanosomiasis. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:7 Topics: Animals; Cell Line; Drug Resistance; Eflornithine; Humans; Mice; Nifurtimox; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR. European journal of medicinal chemistry, 2011, Volume: 46, Issue:1 Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics	2011
Examination of the mode of action of the almiramide family of natural products against the kinetoplastid parasite Trypanosoma brucei. Journal of natural products, 2013, Apr-26, Volume: 76, Issue:4 Topics: Animals; Biological Products; Chagas Disease; Glycolysis; Humans; Leishmania donovani; Lipopeptides; Microbodies; Microscopy, Fluorescence; Trypanosoma brucei brucei; Zebrafish	2013
Kinase scaffold repurposing for neglected disease drug discovery: discovery of an efficacious, lapatinib-derived lead compound for trypanosomiasis. Journal of medicinal chemistry, 2013, May-23, Volume: 56, Issue:10 Topics: Animals; Cell Cycle; Cell Line, Tumor; Cell Survival; Coloring Agents; Drug Design; Drug Discovery; ErbB Receptors; Humans; Indicators and Reagents; Lapatinib; Morpholines; Neglected Diseases; Phosphotransferases; Quinazolines; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	2013
Semisynthesis of salviandulin E analogues and their antitrypanosomal activity. Bioorganic & medicinal chemistry letters, 2014, Jan-15, Volume: 24, Issue:2 Topics: Crystallography, X-Ray; Humans; Plant Extracts; Salvia; Trypanocidal Agents; Trypanosoma brucei brucei	2014
Synthesis, antileishmanial and antitrypanosomal activities of N-substituted tetrahydro-β-carbolines. Bioorganic & medicinal chemistry letters, 2014, Aug-01, Volume: 24, Issue:15 Topics: Animals; Antiprotozoal Agents; Carbolines; Cell Line; Chlorocebus aethiops; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Leishmania donovani; Macrophages; Molecular Structure; Parasitic Sensitivity Tests; Structure-Activity Relationship; Swine; Trypanosoma brucei brucei; Vero Cells	2014
Targeting the HSP60/10 chaperonin systems of Trypanosoma brucei as a strategy for treating African sleeping sickness. Bioorganic & medicinal chemistry letters, 2016, 11-01, Volume: 26, Issue:21 Topics: Animals; Antiprotozoal Agents; Chaperonin 10; Chaperonin 60; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Humans; Trypanosoma brucei brucei; Trypanosomiasis, African	2016
2 H-1,2,3-Triazole-Based Dipeptidyl Nitriles: Potent, Selective, and Trypanocidal Rhodesain Inhibitors by Structure-Based Design. Journal of medicinal chemistry, 2018, 04-26, Volume: 61, Issue:8 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dipeptides; Drug Design; Female; Humans; Leishmania donovani; Ligands; Mice; Microsomes, Liver; Molecular Structure; Nitriles; Plasmodium falciparum; Protozoan Proteins; Rats; Structure-Activity Relationship; Swine; Triazoles; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2018
Chemotherapy of CNS-trypanosomiasis: the combined use of diminazene aceturate or pentamidine with DL-alpha-difluoromethylornithine (DFMO). Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1992, Volume: 43, Issue:2 Topics: Animals; Arsenicals; Central Nervous System Diseases; Diminazene; Drug Administration Schedule; Drug Therapy, Combination; Eflornithine; Female; Mice; Pentamidine; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	1992
New developments in the treatment of Pneumocystis carinii pneumonia. Chest, 1992, Volume: 101, Issue:2 Topics: Adrenal Cortex Hormones; Aerosols; Dapsone; Drug Therapy, Combination; Eflornithine; Folic Acid Antagonists; Humans; Pentamidine; Pneumonia, Pneumocystis; Pyrimidines; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Trimetrexate	1992
Polyamine metabolism in Pneumocystis carinii. The Journal of infectious diseases, 1991, Volume: 163, Issue:5 Topics: Animals; Arginine; Eflornithine; Lung; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Pentamidine; Pneumocystis; Polyamines; Putrescine; Rats; Spermidine; Spermine	1991
Pneumocystis carinii pneumonia treated with eflornithine in AIDS patients resistant to conventional therapy. AIDS (London, England), 1990, Volume: 4, Issue:10 Topics: Acquired Immunodeficiency Syndrome; Eflornithine; Female; Homosexuality; Humans; Male; Pentamidine; Pneumonia, Pneumocystis; Trimethoprim, Sulfamethoxazole Drug Combination	1990
Treatment of Pneumocystis carinii pneumonia in patients with AIDS. Clinical pharmacy, 1988, Volume: 7, Issue:7 Topics: Acquired Immunodeficiency Syndrome; Adrenal Cortex Hormones; Adult; Anti-Infective Agents; Dapsone; Drug Combinations; Eflornithine; Humans; Male; Pentamidine; Pneumonia, Pneumocystis; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination	1988
Method of testing the susceptibility of Pneumocystis carinii to antimicrobial agents in vitro. Antimicrobial agents and chemotherapy, 1985, Volume: 28, Issue:6 Topics: Animals; Cells, Cultured; Dapsone; Drug Combinations; Eflornithine; Lung; Male; Ornithine; Pentamidine; Pneumocystis; Rats; Rats, Inbred Strains; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination	1985
[Current therapy of trypanosomiasis]. Bulletin de la Societe de pathologie exotique (1990), 1994, Volume: 87, Issue:5 Topics: Adenosylmethionine Decarboxylase; Animals; Arsenicals; Deoxyadenosines; Drug Resistance; Eflornithine; Enzyme Inhibitors; Hospitalization; Humans; Melarsoprol; Pentamidine; Randomized Controlled Trials as Topic; Recurrence; Suramin; Triazines; Trypanocidal Agents; Trypanosomiasis, African	1994
[Improved prognosis of first episode HIV associated Pneumocystis carinii pneumonia without preventive treatment: etiology and sequelae]. Pneumologie (Stuttgart, Germany), 1996, Volume: 50, Issue:7 Topics: Adolescent; Adult; Aged; AIDS-Related Opportunistic Infections; Cause of Death; Eflornithine; Female; Humans; Male; Middle Aged; Pentamidine; Pneumonia, Pneumocystis; Prognosis; Respiratory Function Tests; Survival Rate; Trimethoprim, Sulfamethoxazole Drug Combination	1996
Effects of pentamidine on polyamine level and biosynthesis in wild-type, pentamidine-treated, and pentamidine-resistant Leishmania. Experimental parasitology, 1997, Volume: 85, Issue:3 Topics: Animals; Blotting, Western; Chromatography, High Pressure Liquid; Drug Resistance; Eflornithine; Enzyme Inhibitors; Leishmania donovani; Leishmania mexicana; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Pentamidine; Polyamines; Spermidine Synthase; Trypanocidal Agents	1997
[Correspondence of the World Health Organization relative to the editorial by T. Ancelle (Med. Trop. 1996; 56: 347-348)]. Medecine tropicale : revue du Corps de sante colonial, 1997, Volume: 57, Issue:1 Topics: Africa; Eflornithine; France; Global Health; Humans; International Cooperation; Melarsoprol; Pentamidine; Trypanocidal Agents; Trypanosomiasis, African; World Health Organization	1997
In vivo evaluation of sixteen plant extracts on mice inoculated with Trypanosoma brucei gambiense. Bulletin of the World Health Organization, 1997, Volume: 75, Issue:4 Topics: Administration, Oral; Animals; Cote d'Ivoire; Eflornithine; Infusions, Parenteral; Injections, Intraperitoneal; Medicine, Traditional; Melarsoprol; Mice; Pentamidine; Plant Extracts; Sodium Chloride; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African	1997
Anti-sleeping sickness drugs and cancer chemotherapy. Parasitology today (Personal ed.), 2000, Volume: 16, Issue:1 Topics: Animals; Antineoplastic Agents; Eflornithine; Humans; Melarsoprol; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	2000
Availability and affordability of treatment for Human African Trypanosomiasis. Tropical medicine & international health : TM & IH, 2001, Volume: 6, Issue:11 Topics: Eflornithine; Health Services Accessibility; Humans; Melarsoprol; Pentamidine; Research; Suramin; Trypanocidal Agents; Trypanosomiasis, African; World Health Organization	2001
[The return of sleeping sickness in an epidemic form: international action for drugs]. Nederlands tijdschrift voor geneeskunde, 2002, Dec-28, Volume: 146, Issue:52 Topics: Africa, Central; Animals; Disease Outbreaks; Eflornithine; Humans; International Cooperation; Melarsoprol; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African	2002
Retaking sleeping sickness control in Angola. Tropical medicine & international health : TM & IH, 2004, Volume: 9, Issue:1 Topics: Adolescent; Adult; Age Distribution; Aged; Angola; Animals; Child; Child, Preschool; Disease Outbreaks; Eflornithine; Female; Humans; Infant; Insect Vectors; Male; Melarsoprol; Middle Aged; Pentamidine; Sex Distribution; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African; Tsetse Flies	2004
Treatment outcomes and risk factors for relapse in patients with early-stage human African trypanosomiasis (HAT) in the Republic of the Congo. Bulletin of the World Health Organization, 2006, Volume: 84, Issue:10 Topics: Adolescent; Adult; Animals; Child; Cohort Studies; Democratic Republic of the Congo; Disease Progression; Eflornithine; Female; Humans; Male; Pentamidine; Recurrence; Retrospective Studies; Risk Assessment; Risk Factors; Treatment Failure; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African	2006
Pentamidine movement across the murine blood-brain and blood-cerebrospinal fluid barriers: effect of trypanosome infection, combination therapy, P-glycoprotein, and multidrug resistance-associated protein. The Journal of pharmacology and experimental therapeutics, 2009, Volume: 329, Issue:3 Topics: Adenine; Adenosine; Animals; ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Blood-Brain Barrier; Brain; Cerebrospinal Fluid; Disease Models, Animal; Drug Interactions; Eflornithine; Indomethacin; Male; Melarsoprol; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Mice, Knockout; Multidrug Resistance-Associated Proteins; Nifurtimox; Pentamidine; Perfusion; Suramin; Trypanosoma brucei brucei; Trypanosomiasis, African	2009
Human African trypanosomiasis. Lancet (London, England), 2010, Jan-09, Volume: 375, Issue:9709 Topics: Africa; Animals; Biomedical Research; Communicable Disease Control; Eflornithine; Endemic Diseases; Humans; Incidence; Insect Bites and Stings; Insect Vectors; Melarsoprol; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African; Tsetse Flies; Variant Surface Glycoproteins, Trypanosoma	2010
Killer coma: the evolving story of sleeping sickness treatment. Lancet (London, England), 2010, Jan-09, Volume: 375, Issue:9709 Topics: Animals; Biomedical Research; Drug Discovery; Drug Resistance; Drug Therapy, Combination; Eflornithine; Humans; Insect Vectors; Nifurtimox; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African; Tsetse Flies; World Health Organization	2010
Human African trypanosomiasis in Angola: clinical observations, treatment, and use of PCR for stage determination of early stage of the disease. Transactions of the Royal Society of Tropical Medicine and Hygiene, 2012, Volume: 106, Issue:1 Topics: Adult; Angola; Animals; Eflornithine; Female; Follow-Up Studies; Humans; Lymphocyte Count; Male; Nucleic Acid Amplification Techniques; Pentamidine; Polymerase Chain Reaction; Recurrence; Remission Induction; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African	2012
High-throughput decoding of antitrypanosomal drug efficacy and resistance. Nature, 2012, Jan-25, Volume: 482, Issue:7384 Topics: Aquaglyceroporins; Drug Resistance; Eflornithine; Endocytosis; Glycosylation; High-Throughput Screening Assays; Humans; Lysosomes; Melarsoprol; Nifurtimox; Pentamidine; RNA Interference; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	2012
Evaluation of trypanocidal drugs used for human African trypanosomosis against Trypanosoma lewisi. Parasite (Paris, France), 2013, Volume: 20 Topics: Animals; Eflornithine; Female; Humans; Immunocompromised Host; Inhibitory Concentration 50; Melarsoprol; Mice; Nifurtimox; Nitroimidazoles; Parasitemia; Pentamidine; Rats; Rats, Wistar; Suramin; Trypanocidal Agents; Trypanosoma lewisi; Trypanosomiasis	2013
African sleeping sickness. British journal of hospital medicine (London, England : 2005), 2016, Volume: 77, Issue:10 Topics: Animals; Eflornithine; Humans; Insect Vectors; Nifurtimox; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Tsetse Flies	2016
Design, Synthesis and Biological Evaluation of 7-arylbenzo[c]acridine-5,6- diones as Potential Anti-Leishmanial and anti-trypanosomal Agents. Medicinal chemistry (Shariqah (United Arab Emirates)), 2018, Volume: 14, Issue:6 Topics: Acridines; Amphotericin B; Animals; Chlorocebus aethiops; Doxorubicin; Drug Design; Eflornithine; Hep G2 Cells; Humans; Leishmania donovani; Parasitic Sensitivity Tests; Pentamidine; Swine; Trypanocidal Agents; Trypanosoma brucei brucei; Vero Cells	2018