pentamidine and benzonidazole

pentamidine has been researched along with benzonidazole in 46 studies

Research

Studies (46)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (2.17)	18.7374
1990's	0 (0.00)	18.2507
2000's	15 (32.61)	29.6817
2010's	28 (60.87)	24.3611
2020's	2 (4.35)	2.80

Authors

Authors	Studies
Chibale, K; Croft, SL; Fairlamb, AH; Visser, M; Yardley, V	1
Croft, SL; Gilbert, IH; Kendrick, H; Khabnadideh, S; Tan, CL; Yardley, V	1
Bressi, JC; Gelb, MH; Kennedy, KJ	1
Bailey, BN; Caldera, A; Croft, SL; Docampo, R; Grimley, JS; Heath, HT; Kendrick, H; Lewis, JC; Lira, R; Martin, MB; Moreno, SN; Oldfield, E; Urbina, JA; Yardley, V	1
Aronov, AM; Bressi, JC; Buckner, FS; Gelb, MH; Hol, WG; Kuntz, ID; Nguyen, LN; Shaw, ML; Shin, SS; Suresh, S; Van Voorhis, WC; Verlinde, CL	1
Boykin, DW; Brun, R; Salem, MM; Stephens, CE; Tanious, F; Werbovetz, KA; Wilson, WD	1
Baliani, A; Barrett, MP; Brun, R; Bueno, GJ; Gilbert, IH; Stewart, ML; Yardley, V	1
Bauer, H; Davioud-Charvet, E; Krauth-Siegel, RL; Lee, B; Melchers, J; Rattray, L; Ruppert, T; Yardley, V	1
Boiani, L; Boiani, M; Cerecetto, H; Denicola, A; Gómez-Barrio, A; Gonzalez, M; Nakayama, H; Rojas de Arias, A; Rolan, M; Sanabria, L; Serna, E; Torres de Ortiz, S; Vega, C; Vera de Bilbao, N; Yaluff, G	1
Croft, SL; Gilbert, IH; Gonzalez-Pacanowska, D; Gros, L; Jimenez, CJ; Little, S; Lorente, SO; Rattray, L; Ruiz-Perez, LM; Wharton, H; Yardley, V	1
del Olmo, E; Giménez, A; López-Pérez, JL; Rebollo, O; Ruiz, G; San Feliciano, A	1
Berlinck, RG; Cavalcanti, BC; Ferreira, AG; Hajdu, E; Kossuga, MH; Mayer, AM; Moraes, MO; Nascimento, AM; Pessoa, C; Reimão, JQ; Taniwaki, NN; Tempone, AG; Veloso, K	1
Ferreira, ME; Gómez-Barrio, A; Heguaburu, V; Marrero-Ponce, Y; Montero-Torres, A; Nakayama, H; Pandolfi, E; Rojas de Arias, A; Roldos, V; Rolón, M; Sanabria, L; Torres, S; Trucco, F; Vega, C; Yaluff, G	1
Arán, VJ; Boiani, L; Cerecetto, H; Gerpe, A; González, M; Maya, JD; Morello, JA; Nakayama, H; Rojas de Arias, A; Sanabria, L; Serna, E; Torres de Ortiz, S; Vera de Bilbao, N; Yaluff, G	1
Bazzocchi, IL; Bourdy, G; Flores, N; Giménez, A; Gutiérrez, D; Jiménez, IA; Ruiz, G	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fairlamb, AH; Oza, SL; Patterson, S; Read, KD; Sokolova, AY; Wyllie, S	1
Cedillo-Rivera, R; Chan-Bacab, MJ; Estrada-Soto, S; Guerrero-Alvarez, J; León-Rivera, I; Mirón-López, G; Molina-Salinas, GM; Moo-Puc, R; Nava-Zuazo, C; Navarrete-Vazquez, G; Said-Fernández, S	1
Baumann, K; Bischof, SK; Bringmann, G; Brun, R; Dreher, J; Gulder, T; Kaiser, M; Moll, H; Müller, S; Stich, A; Winter, C	1
Reimão, JQ; Scotti, MT; Tempone, AG	1
Argotte-Ramos, R; Cedillo-Rivera, R; Chan-Bacab, MJ; Chávez-Silva, F; Hernández-Nuñez, E; Moo-Puc, R; Navarrete-Vazquez, G; Rodríguez-Gutiérrez, Mdel C	1
Bolzani, VS; Cicarelli, RM; Furlan, M; Graminha, MA; Martinez, I; Nogueira, CR; Passerini, GD; Regasini, LO; Santos, VA	1
Arafa, RK; Boykin, DW; Brun, R; Ismail, MA; Jones, SK; Pandharkar, T; Patrick, DA; Tidwell, RR; Wenzler, T; Werbovetz, KA; Zhu, X	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Brun, R; Harel, D; Prinz, H; Schepmann, D; Schmidt, TJ; Wünsch, B	1
Chan-Bacab, MJ; Chávez-Silva, F; Díaz-Coutiño, D; Hernández-Núñez, E; Moo-Puc, R; Moreno-Díaz, H; Nava-Zuazo, C; Navarrete-Vázquez, G; Ortega-Morales, BO	1
Chiari, BG; Cicarelli, RM; de Almeida, MG; Francisco, AI; Isaac, VL; Kohatsu, AA; Rodrigues, DF; Silva, FA; Teixeira, RG; Vargas, MD; Velásquez, AM	1
Boykin, DW; Brun, R; Liu, ZY; Wenzler, T; Zhu, X	1
Avery, VM; Baell, JB; Bergström, CA; Charman, SA; Ferrins, L; Gazdik, M; Jones, AJ; Kaiser, M; Rahmani, R; Ryan, E; Sykes, ML; Varghese, S; White, KL	1
Bolzani, Vda S; de Almeida, L; dos Santos, MB; Dutra, LA; Graminha, MA; Michels, PA; Passalacqua, TG; Regasini, LO; Torres, FA; Velásquez, AM; Yamasaki, PR	1
Bosc, D; Cojean, S; Dubois, J; Franco, CH; Freitas-Junior, LH; Grellier, P; Loiseau, PM; Moraes, CB; Mouray, E	1
Argüello-Garcia, R; Barbosa-Cabrera, E; Chan-Bacab, MJ; Colín-Lozano, B; Hernández-Núñez, E; León-Rivera, I; López-Guerrero, V; Moo-Puc, R; Navarrete-Vázquez, G; Ortega-Morales, BO; Scior, T	1
Buckner, FS; Gelb, MH; Gillespie, JR; Herbst, ZM; Montanari, CA; Nguyen, UTT; Ranade, RM; Silva, DG	1
Jäger, SN; Labadie, GR; Lepesheva, GI; Nocito, I; Porta, EOJ; Serra, EC; Tekwani, BL	1
Alcantara, LM; Cordeiro-da-Silva, A; Costantino, L; Costi, MP; Ellinger, B; Ferrari, S; Franco, CH; Freitas-Junior, LH; Gul, S; Kuzikov, M; Linciano, P; Luciani, R; Macedo, S; Moraes, CB; Pascoalino, B; Quotadamo, A; Santarem, N; Witt, G	1
Cantizani, J; Cogo, J; Corrêa, AG; Cotillo, I; Filho, BPD; Martín, JJ; Nakamura, CV; Sangi, DP; Ueda-Nakamura, T	1
Azas, N; Basmaciyan, L; Belle Mbou, V; Boudot, C; Bourgeade-Delmas, S; Boutet-Robinet, É; Casanova, M; Castera-Ducros, C; Cohen, A; Courtioux, B; Fairlamb, AH; Fersing, C; Hutter, S; Laget, M; Milne, R; Pedron, J; Piednoel, M; Primas, N; Rathelot, P; Since, M; Sournia-Saquet, A; Valentin, A; Vanelle, P; Verhaeghe, P; Wyllie, S	1
Buckner, FS; Faghih, O; Gelb, MH; Gillespie, JR; Herbst, ZM; Molasky, NMR; Nagendar, P; Ranade, RM; Turner, RM	1
Caljon, G; Campagnaro, GD; de Koning, HP; Hulpia, F; Maes, L; Scortichini, M; Van Calenbergh, S; Van Hecke, K	1
Baptista, C; Bonucci, A; Cordeiro-da-Silva, A; Costantino, L; Costi, MP; di Pisa, F; Ellinger, B; Ferrari, S; Franco, C; Gul, S; Iacono, LD; Kuzikov, M; Landi, G; Linciano, P; Luciani, R; Mangani, S; Moraes, CB; Müller, W; Pöhner, I; Pozzi, C; Quotadamo, A; Santarem, N; Sesenna, A; Witt, G; Wittig, U	1
La-Venia, A; Labadie, GR; Medrán, NS; Pereira, CA; Sayé, M; Tekwani, BL	1
Andrade, SF; Barbosa da Silva, E; Caffrey, CR; Ferreira, RS; Fortes, IS; McKerrow, J; Monti, L; Rocha, DA; Siqueira-Neto, JL; Yang, W	1
Gutteridge, WE	1
Barrett, MP; Croft, SL	1
Batista, MM; Boykin, DW; Da Silva, PB; Farahat, AA; Kumar, A; Soeiro, MN; Timm, BL	1
Campos-Estrada, C; Castro, L; Cortes, L; Díaz, MV; Kemmerling, U; Lapier, M; López-Muñoz, R; Maya, JD; Miranda, MR; Morello, A; Pereira, CA; Reigada, C; Seguel, V	1

Reviews

2 review(s) available for pentamidine and benzonidazole

Article	Year
Existing chemotherapy and its limitations. British medical bulletin, 1985, Volume: 41, Issue:2 Topics: Chagas Disease; Gentian Violet; Humans; Melarsoprol; Nifurtimox; Nitroimidazoles; Pentamidine; Suramin; Trypanocidal Agents; Trypanosomiasis, African	1985
Management of trypanosomiasis and leishmaniasis. British medical bulletin, 2012, Volume: 104 Topics: Administration, Oral; Africa; Amphotericin B; Antiprotozoal Agents; Benzamides; Boron Compounds; Chagas Disease; Drug Therapy, Combination; Humans; India; Leishmaniasis; Nitroimidazoles; Pentamidine; Triazoles; Trypanosomiasis, African	2012

Other Studies

44 other study(ies) available for pentamidine and benzonidazole

Article	Year
Synthesis and evaluation of 9,9-dimethylxanthene tricyclics against trypanothione reductase, Trypanosoma brucei, Trypanosoma cruzi and Leishmania donovani. Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11 Topics: Animals; Antiprotozoal Agents; Enzyme Inhibitors; Leishmania donovani; NADH, NADPH Oxidoreductases; Trypanosoma brucei brucei; Trypanosoma cruzi; Xanthenes	2000
Squalamine analogues as potential anti-trypanosomal and anti-leishmanial compounds. Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11 Topics: Animals; Antiprotozoal Agents; Cholestanols; Leishmania donovani; Trypanosoma brucei brucei; Trypanosoma cruzi	2000
A disubstituted NAD+ analogue is a nanomolar inhibitor of trypanosomal glyceraldehyde-3-phosphate dehydrogenase. Bioorganic & medicinal chemistry letters, 2001, Jan-22, Volume: 11, Issue:2 Topics: 3T3 Cells; Animals; Antiprotozoal Agents; Cell Culture Techniques; Enzyme Inhibitors; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Inhibitory Concentration 50; Mice; Muscle, Skeletal; NAD; Rabbits; Structure-Activity Relationship; Trypanosoma	2001
Bisphosphonates inhibit the growth of Trypanosoma brucei, Trypanosoma cruzi, Leishmania donovani, Toxoplasma gondii, and Plasmodium falciparum: a potential route to chemotherapy. Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6 Topics: Animals; Antiprotozoal Agents; Chlorocebus aethiops; Diphosphonates; Leishmania donovani; Plasmodium falciparum; Structure-Activity Relationship; Toxoplasma; Trypanosoma brucei brucei; Trypanosoma cruzi; Vero Cells	2001
Adenosine analogues as selective inhibitors of glyceraldehyde-3-phosphate dehydrogenase of Trypanosomatidae via structure-based drug design. Journal of medicinal chemistry, 2001, Jun-21, Volume: 44, Issue:13 Topics: 3T3 Cells; Adenosine; Animals; Combinatorial Chemistry Techniques; Drug Design; Enzyme Inhibitors; Glyceraldehyde-3-Phosphate Dehydrogenases; Leishmania mexicana; Mice; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma cruzi; Trypanosomatina	2001
The activity of diguanidino and 'reversed' diamidino 2,5-diarylfurans versus Trypanosoma cruzi and Leishmania donovani. Bioorganic & medicinal chemistry letters, 2003, Jun-16, Volume: 13, Issue:12 Topics: Amidines; Animals; DNA; Furans; Guanidine; Inhibitory Concentration 50; Leishmania donovani; Macrophages; Nucleic Acid Denaturation; Oligodeoxyribonucleotides; Poly dA-dT; Protozoan Proteins; Structure-Activity Relationship; Temperature; Trypanocidal Agents; Trypanosoma cruzi	2003
Design and synthesis of a series of melamine-based nitroheterocycles with activity against Trypanosomatid parasites. Journal of medicinal chemistry, 2005, Aug-25, Volume: 48, Issue:17 Topics: Animals; Cell Line; Female; Furaldehyde; Hydrazones; Leishmania donovani; Mice; Nitrofurans; Nucleoside Transport Proteins; Rats; Thiophenes; Triazines; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense; Trypanosoma cruzi; Trypanosomiasis, African	2005
Irreversible inactivation of trypanothione reductase by unsaturated Mannich bases: a divinyl ketone as key intermediate. Journal of medicinal chemistry, 2005, Nov-17, Volume: 48, Issue:23 Topics: Animals; Antimalarials; Antiprotozoal Agents; Chromatography, High Pressure Liquid; Dimethyl Sulfoxide; Drug Storage; Glutathione; Glutathione Reductase; Humans; Ketones; Leishmania donovani; Magnetic Resonance Spectroscopy; Mannich Bases; NADH, NADPH Oxidoreductases; Plasmodium falciparum; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thioredoxin-Disulfide Reductase; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2005
2H-benzimidazole 1,3-dioxide derivatives: a new family of water-soluble anti-trypanosomatid agents. Journal of medicinal chemistry, 2006, Jun-01, Volume: 49, Issue:11 Topics: Acute Disease; Animals; Benzimidazoles; Cell Line; Chagas Disease; Cyclic N-Oxides; Leishmania; Macrophages; Mice; Mice, Inbred BALB C; Models, Molecular; Oxidation-Reduction; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi	2006
Evaluation of azasterols as anti-parasitics. Journal of medicinal chemistry, 2006, Oct-05, Volume: 49, Issue:20 Topics: Animals; Antimalarials; Azasteroids; Leishmania donovani; Methyltransferases; Plasmodium falciparum; Stereoisomerism; Sterols; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2006
Leishmanicidal and trypanocidal activities of 2-aminocyclohexanol and 1,2-cyclohexanediamine derivatives. Bioorganic & medicinal chemistry letters, 2008, Jan-01, Volume: 18, Issue:1 Topics: Animals; Cyclohexanes; Cyclohexanols; Diamines; Inhibitory Concentration 50; Leishmania; Sphingosine; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi	2008
Antiparasitic, antineuroinflammatory, and cytotoxic polyketides from the marine sponge Plakortis angulospiculatus collected in Brazil. Journal of natural products, 2008, Volume: 71, Issue:3 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Antiprotozoal Agents; Brazil; Cricetinae; Drug Screening Assays, Antitumor; Erythrocytes; Humans; Leishmania infantum; Macrolides; Macrophages; Marine Biology; Mesocricetus; Mice; Mice, Inbred BALB C; Molecular Structure; Neurogenic Inflammation; Nitric Oxide; Plakortis; Trypanosoma cruzi	2008
Activity of a hydroxybibenzyl bryophyte constituent against Leishmania spp. and Trypanosoma cruzi: in silico, in vitro and in vivo activity studies. European journal of medicinal chemistry, 2008, Volume: 43, Issue:9 Topics: Animals; Antiprotozoal Agents; Bibenzyls; Cattle; Cell Line; Computational Biology; Extracellular Space; Female; Inhibitory Concentration 50; Intracellular Space; Leishmania; Leishmaniasis; Male; Mice; Phenols; Trypanosoma cruzi	2008
In vitro and in vivo antitrypanosomatid activity of 5-nitroindazoles. European journal of medicinal chemistry, 2009, Volume: 44, Issue:3 Topics: Animals; Drug Evaluation, Preclinical; In Vitro Techniques; Indazoles; Leishmania; Mice; Trypanocidal Agents; Trypanosoma cruzi	2009
Benzoic acid derivatives from Piper species and their antiparasitic activity. Journal of natural products, 2008, Volume: 71, Issue:9 Topics: Animals; Antimalarials; Antiparasitic Agents; Antiprotozoal Agents; Benzoates; Bolivia; Leishmania; Molecular Structure; Parasitic Sensitivity Tests; Piper; Plant Leaves; Plants, Medicinal; Plasmodium falciparum; Trypanosoma cruzi	2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Cross-resistance to nitro drugs and implications for treatment of human African trypanosomiasis. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:7 Topics: Animals; Cell Line; Drug Resistance; Eflornithine; Humans; Mice; Nifurtimox; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	2010
Design, synthesis, and in vitro antiprotozoal, antimycobacterial activities of N-{2-[(7-chloroquinolin-4-yl)amino]ethyl}ureas. Bioorganic & medicinal chemistry, 2010, Sep-01, Volume: 18, Issue:17 Topics: Anti-Bacterial Agents; Antiprotozoal Agents; Drug Design; Giardia lamblia; Humans; Leishmania mexicana; Mycobacterium tuberculosis; Quinolines; Structure-Activity Relationship; Urea	2010
QSAR guided synthesis of simplified antiplasmodial analogs of naphthylisoquinoline alkaloids. European journal of medicinal chemistry, 2010, Volume: 45, Issue:11 Topics: Alkaloids; Animals; Antimalarials; Isoquinolines; Magnetic Resonance Spectroscopy; Models, Molecular; Plasmodium falciparum; Quantitative Structure-Activity Relationship; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared	2010
Anti-leishmanial and anti-trypanosomal activities of 1,4-dihydropyridines: In vitro evaluation and structure-activity relationship study. Bioorganic & medicinal chemistry, 2010, Nov-15, Volume: 18, Issue:22 Topics: Animals; Antiprotozoal Agents; Cell Line; Cricetinae; Dihydropyridines; Erythrocytes; Leishmania; Macaca mulatta; Mice; Parasitic Sensitivity Tests; Quantitative Structure-Activity Relationship; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi	2010
Synthesis of benzologues of Nitazoxanide and Tizoxanide: a comparative study of their in vitro broad-spectrum antiprotozoal activity. Bioorganic & medicinal chemistry letters, 2011, May-15, Volume: 21, Issue:10 Topics: Antiprotozoal Agents; Giardia; Molecular Structure; Nitro Compounds; Plasmodium; Thiazoles; Trichomonas vaginalis	2011
Antiprotozoal sesquiterpene pyridine alkaloids from Maytenus ilicifolia. Journal of natural products, 2012, May-25, Volume: 75, Issue:5 Topics: Alkaloids; Animals; Antiprotozoal Agents; Brazil; Leishmania; Macrophages, Peritoneal; Maytenus; Mice; Molecular Structure; Plant Bark; Plant Roots; Pyridines; Sesquiterpenes; Trypanosoma cruzi	2012
Synthesis and antiprotozoal activity of dicationic m-terphenyl and 1,3-dipyridylbenzene derivatives. Journal of medicinal chemistry, 2013, Jul-11, Volume: 56, Issue:13 Topics: Animals; Antiprotozoal Agents; Benzene; Chagas Disease; Female; Leishmania donovani; Mice; Mice, Inbred Strains; Models, Chemical; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyridines; Structure-Activity Relationship; Terphenyl Compounds; Trypanosoma cruzi	2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Natural product derived antiprotozoal agents: synthesis, biological evaluation, and structure-activity relationships of novel chromene and chromane derivatives. Journal of medicinal chemistry, 2013, Sep-26, Volume: 56, Issue:18 Topics: Antiprotozoal Agents; Biological Products; Chemistry Techniques, Synthetic; Chromans; Inhibitory Concentration 50; Structure-Activity Relationship	2013
2-acylamino-5-nitro-1,3-thiazoles: preparation and in vitro bioevaluation against four neglected protozoan parasites. Bioorganic & medicinal chemistry, 2014, Mar-01, Volume: 22, Issue:5 Topics: Animals; Antiprotozoal Agents; Drug Design; Humans; Protozoan Infections; Thiazoles	2014
Synthesis and tripanocidal activity of ferrocenyl and benzyl diamines against Trypanosoma brucei and Trypanosoma cruzi. Bioorganic & medicinal chemistry letters, 2014, Apr-01, Volume: 24, Issue:7 Topics: Benzyl Compounds; Cell Survival; Diamines; Dose-Response Relationship, Drug; Ferrous Compounds; Hep G2 Cells; Humans; Metallocenes; Molecular Structure; Parasitic Sensitivity Tests; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma cruzi	2014
Synthesis and antiparasitic activity of new bis-arylimidamides: DB766 analogs modified in the terminal groups. European journal of medicinal chemistry, 2014, Aug-18, Volume: 83 Topics: Amides; Animals; Antiparasitic Agents; Cell Line; Chemistry Techniques, Synthetic; Leishmania; Plasmodium falciparum; Rats; Trypanosoma	2014
Pyridyl benzamides as a novel class of potent inhibitors for the kinetoplastid Trypanosoma brucei. Journal of medicinal chemistry, 2014, Aug-14, Volume: 57, Issue:15 Topics: Animals; Benzamides; Cell Line; HEK293 Cells; Humans; Microsomes, Liver; Myoblasts; Pyridines; Rats; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense	2014
Synthesis and evaluation of novel prenylated chalcone derivatives as anti-leishmanial and anti-trypanosomal compounds. Bioorganic & medicinal chemistry letters, 2015, Aug-15, Volume: 25, Issue:16 Topics: Chalcone; Inhibitory Concentration 50; Leishmania infantum; Prenylation; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi	2015
Highly improved antiparasitic activity after introduction of an N-benzylimidazole moiety on protein farnesyltransferase inhibitors. European journal of medicinal chemistry, 2016, Feb-15, Volume: 109 Topics: Alkyl and Aryl Transferases; Animals; Antiparasitic Agents; Cell Line; Enzyme Inhibitors; Humans; Imidazoles; Leishmania donovani; Leishmaniasis, Visceral; Malaria, Falciparum; Mice; Parasitic Sensitivity Tests; Plasmodium falciparum; Trypanosoma; Trypanosoma brucei brucei; Trypanosoma cruzi; Trypanosomiasis	2016
Synthesis, in vitro and in vivo giardicidal activity of nitrothiazole-NSAID chimeras displaying broad antiprotozoal spectrum. Bioorganic & medicinal chemistry letters, 2017, 08-01, Volume: 27, Issue:15 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antiprotozoal Agents; Drug Design; Female; Giardia lamblia; Giardiasis; Humans; Leishmania; Mice; Nitro Compounds; Protozoan Infections; Thiazoles; Trichomonas vaginalis; Trypanosoma cruzi	2017
New Class of Antitrypanosomal Agents Based on Imidazopyridines. ACS medicinal chemistry letters, 2017, Jul-13, Volume: 8, Issue:7 Topics:	2017
Antitrypanosomal and antileishmanial activity of prenyl-1,2,3-triazoles. MedChemComm, 2017, May-01, Volume: 8, Issue:5 Topics:	2017
Aryl thiosemicarbazones for the treatment of trypanosomatidic infections. European journal of medicinal chemistry, 2018, Feb-25, Volume: 146 Topics: Antiprotozoal Agents; Chagas Disease; Dose-Response Relationship, Drug; Humans; Macrophages; Molecular Structure; Parasitic Sensitivity Tests; Structure-Activity Relationship; Thiosemicarbazones; Trypanosoma	2018
Quinoxaline derivatives as potential antitrypanosomal and antileishmanial agents. Bioorganic & medicinal chemistry, 2018, 08-07, Volume: 26, Issue:14 Topics: Antiprotozoal Agents; Dose-Response Relationship, Drug; Leishmania donovani; Molecular Structure; Parasitic Sensitivity Tests; Quinoxalines; Structure-Activity Relationship; Trypanosoma brucei brucei; Trypanosoma cruzi	2018
Nongenotoxic 3-Nitroimidazo[1,2- ACS medicinal chemistry letters, 2019, Jan-10, Volume: 10, Issue:1 Topics:	2019
Triazolopyrimidines and Imidazopyridines: Structure-Activity Relationships and in Vivo Efficacy for Trypanosomiasis. ACS medicinal chemistry letters, 2019, Jan-10, Volume: 10, Issue:1 Topics:	2019
Revisiting tubercidin against kinetoplastid parasites: Aromatic substitutions at position 7 improve activity and reduce toxicity. European journal of medicinal chemistry, 2019, Feb-15, Volume: 164 Topics: Animals; Biological Transport; Kinetoplastida; Mice; Nucleoside Transport Proteins; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Tubercidin	2019
Enhancement of Benzothiazoles as Pteridine Reductase-1 Inhibitors for the Treatment of Trypanosomatidic Infections. Journal of medicinal chemistry, 2019, 04-25, Volume: 62, Issue:8 Topics: Animals; Antiprotozoal Agents; Benzothiazoles; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Drug Design; Enzyme Inhibitors; Half-Life; Leishmania major; Mice; Mice, Inbred BALB C; Molecular Docking Simulation; Oxidoreductases; Protozoan Proteins; Structure-Activity Relationship; Trypanosoma brucei brucei; Trypanosomiasis	2019
Expanding the scope of synthetic 1,2,4-trioxanes towards Trypanosoma cruzi and Leishmania donovani. Bioorganic & medicinal chemistry letters, 2020, 10-15, Volume: 30, Issue:20 Topics: Antiparasitic Agents; Dose-Response Relationship, Drug; Heterocyclic Compounds; Leishmania donovani; Molecular Structure; Parasitic Sensitivity Tests; Structure-Activity Relationship; Trypanosoma cruzi	2020
Structure-Based Optimization of Quinazolines as Cruzain and Journal of medicinal chemistry, 2021, 09-09, Volume: 64, Issue:17 Topics: Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Models, Molecular; Molecular Structure; Protein Conformation; Protozoan Proteins; Structure-Activity Relationship; Trypanosoma brucei brucei; Trypanosoma cruzi	2021
In vitro investigation of the efficacy of novel diamidines against Trypanosoma cruzi. Parasitology, 2014, Volume: 141, Issue:10 Topics: Amidines; Animals; Cell Culture Techniques; Chagas Disease; Dose-Response Relationship, Drug; Heart; Humans; Nitroimidazoles; Parasitic Sensitivity Tests; Pentamidine; Trypanocidal Agents; Trypanosoma cruzi	2014
Pentamidine antagonizes the benznidazole's effect in vitro, and lacks of synergy in vivo: Implications about the polyamine transport as an anti-Trypanosoma cruzi target. Experimental parasitology, 2016, Volume: 171 Topics: Animals; Chagas Disease; Chlorocebus aethiops; DNA, Protozoan; Dose-Response Relationship, Drug; Glutathione; Macrophages; Male; Mice; Mice, Inbred BALB C; Myocardium; Nitroimidazoles; Parasitemia; Pentamidine; Putrescine; Random Allocation; Spermidine; Thymidine; Trypanocidal Agents; Trypanosoma cruzi; Vero Cells	2016