pentamidine and adenosine

pentamidine has been researched along with adenosine in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (43.75)18.2507
2000's5 (31.25)29.6817
2010's3 (18.75)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Caljon, G; Campagnaro, GD; de Koning, HP; Hulpia, F; Maes, L; Scortichini, M; Van Calenbergh, S; Van Hecke, K1
Alfayez, IA; Bouton, J; Caljon, G; Campagnaro, GD; de Koning, HP; Hulpia, F; Mabille, D; Maes, L; Van Calenbergh, S1
Berger, BJ; Carter, NS; Fairlamb, AH2
Asiri, S; Ogbunude, PO; Warhurst, DC1
Baltz, T; Barrett, MP; Denise, H; Giroud, C; Zhang, ZQ1
Scott, AG; Tait, A; Turner, CM1
Ballet, JJ; Brasseur, P; Delaunay, A; Favennec, L; Gargala, G1
de Koning, HP; Jarvis, SM2
Barrett, MP; Brun, R; Burchmore, RJ; de Koning, HP; Enyaru, JC; Geiser, F; Kaminsky, R; Mäser, P; Matovu, E; Seebeck, T; Stewart, ML; Wallace, LJ1
De Koning, HP; Dogruel, M; Rodgers, J; Sanderson, L; Thomas, SA1
Al-Salabi, MI; Augustyns, K; Berg, M; Castagna, V; Cos, P; de Koning, HP; Degano, M; Giannese, F; Grellier, P; Haemers, A; Joossens, J; Kohl, L; Maes, L; Steyaert, J; Van der Veken, P; Versées, W1

Reviews

1 review(s) available for pentamidine and adenosine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

15 other study(ies) available for pentamidine and adenosine

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Revisiting tubercidin against kinetoplastid parasites: Aromatic substitutions at position 7 improve activity and reduce toxicity.
    European journal of medicinal chemistry, 2019, Feb-15, Volume: 164

    Topics: Animals; Biological Transport; Kinetoplastida; Mice; Nucleoside Transport Proteins; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Tubercidin

2019
C6-O-alkylated 7-deazainosine nucleoside analogues: Discovery of potent and selective anti-sleeping sickness agents.
    European journal of medicinal chemistry, 2020, Feb-15, Volume: 188

    Topics: Alkylation; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Discovery; Humans; Inosine; Molecular Structure; Nucleosides; Parasitic Sensitivity Tests; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei

2020
Uptake of diamidine drugs by the P2 nucleoside transporter in melarsen-sensitive and -resistant Trypanosoma brucei brucei.
    The Journal of biological chemistry, 1995, Nov-24, Volume: 270, Issue:47

    Topics: Adenosine; Animals; Arsenicals; Biological Transport; Carrier Proteins; Drug Resistance; Kinetics; Pentamidine; Species Specificity; Structure-Activity Relationship; Trypanosoma brucei brucei

1995
In vitro assessment of susceptibility of Acanthamoeba polyphaga to drugs using combined methods of dye-binding assay and uptake of radiolabelled adenosine.
    International journal for parasitology, 1994, Volume: 24, Issue:7

    Topics: Acanthamoeba; Adenosine; Amebicides; Animals; Antimalarials; Antiprotozoal Agents; Biological Transport; Carbon Radioisotopes; Cell Division; Dose-Response Relationship, Drug; Eosine Yellowish-(YS); Isotope Labeling; Pentamidine

1994
Characterisation of pentamidine-resistant Trypanosoma brucei brucei.
    Molecular and biochemical parasitology, 1995, Volume: 69, Issue:2

    Topics: Adenosine; Animals; Biological Transport, Active; Drug Resistance; Male; Mice; Pentamidine; Rats; Rats, Sprague-Dawley; Trypanosoma brucei brucei; Virulence

1995
A diamidine-resistant Trypanosoma equiperdum clone contains a P2 purine transporter with reduced substrate affinity.
    Molecular and biochemical parasitology, 1995, Volume: 73, Issue:1-2

    Topics: Adenosine; Animals; Arsenicals; Biological Transport, Active; Carrier Proteins; Diminazene; Drug Resistance; Kinetics; Pentamidine; Receptors, Purinergic P2; Trypanocidal Agents; Trypanosoma

1995
Trypanosoma brucei: lack of cross-resistance to melarsoprol in vitro by cymelarsan-resistant parasites.
    Experimental parasitology, 1997, Volume: 86, Issue:3

    Topics: Adenine; Adenosine; Animals; Arsenicals; Diminazene; Dose-Response Relationship, Drug; Drug Resistance; Enzyme Inhibitors; Female; Inosine; Melarsoprol; Mice; Pentamidine; Trypanocidal Agents; Trypanosoma brucei brucei

1997
Enzyme immunoassay detection of Cryptosporidium parvum inhibition by sinefungin in sporozoite infected HCT-8 enterocytic cells.
    International journal for parasitology, 1999, Volume: 29, Issue:5

    Topics: Adenosine; Amebicides; Animals; Antiprotozoal Agents; Cell Line; Cryptosporidium parvum; Dose-Response Relationship, Drug; Fluorescent Antibody Technique, Indirect; Humans; Immunoenzyme Techniques; Parasite Egg Count; Paromomycin; Pentamidine; Rats; Rats, Sprague-Dawley; Time Factors

1999
Adenosine transporters in bloodstream forms of Trypanosoma brucei brucei: substrate recognition motifs and affinity for trypanocidal drugs.
    Molecular pharmacology, 1999, Volume: 56, Issue:6

    Topics: Adenosine; Amino Acid Motifs; Animals; Binding Sites; Biological Transport; Carrier Proteins; Membrane Transport Proteins; Nuclear Proteins; Pentamidine; Protozoan Proteins; Receptors, Purinergic P1; Trypanocidal Agents; Trypanosoma brucei brucei

1999
Uptake of pentamidine in Trypanosoma brucei brucei is mediated by the P2 adenosine transporter and at least one novel, unrelated transporter.
    Acta tropica, 2001, Dec-21, Volume: 80, Issue:3

    Topics: Adenosine; Animals; Biological Transport; Carrier Proteins; Drug Resistance; Membrane Proteins; Nucleoside Transport Proteins; Pentamidine; Rats; Trypanocidal Agents; Trypanosoma brucei brucei

2001
Mechanisms of arsenical and diamidine uptake and resistance in Trypanosoma brucei.
    Eukaryotic cell, 2003, Volume: 2, Issue:5

    Topics: Adenine; Adenosine; Animals; Arsenicals; Benzamidines; Cell Death; Cell Division; Diminazene; Drug Resistance; Female; Gene Silencing; Hypoxanthine; Inhibitory Concentration 50; Inosine; Melarsoprol; Mice; Mutation; Nucleoside Transport Proteins; Pentamidine; Stilbamidines; Trypanosoma brucei brucei

2003
Pentamidine movement across the murine blood-brain and blood-cerebrospinal fluid barriers: effect of trypanosome infection, combination therapy, P-glycoprotein, and multidrug resistance-associated protein.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 329, Issue:3

    Topics: Adenine; Adenosine; Animals; ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Blood-Brain Barrier; Brain; Cerebrospinal Fluid; Disease Models, Animal; Drug Interactions; Eflornithine; Indomethacin; Male; Melarsoprol; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Mice, Knockout; Multidrug Resistance-Associated Proteins; Nifurtimox; Pentamidine; Perfusion; Suramin; Trypanosoma brucei brucei; Trypanosomiasis, African

2009
Evaluation of nucleoside hydrolase inhibitors for treatment of African trypanosomiasis.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:5

    Topics: Adenosine; Animals; Antiprotozoal Agents; Carrier Proteins; Gene Knockdown Techniques; Melarsoprol; Mice; Models, Chemical; N-Glycosyl Hydrolases; Pentamidine; RNA, Small Interfering; Trypanosoma brucei brucei; Trypanosomiasis, African

2010