Page last updated: 2024-09-04

pentamethylmonomethylolmelamine and altretamine

pentamethylmonomethylolmelamine has been researched along with altretamine in 6 studies

Compound Research Comparison

Studies
(pentamethylmonomethylolmelamine)
Trials
(pentamethylmonomethylolmelamine)
Recent Studies (post-2010)
(pentamethylmonomethylolmelamine)
Studies
(altretamine)
Trials
(altretamine)
Recent Studies (post-2010) (altretamine)
60047910726

Protein Interaction Comparison

ProteinTaxonomypentamethylmonomethylolmelamine (IC50)altretamine (IC50)
Cytochrome P450 1A2Homo sapiens (human)4

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19905 (83.33)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abikhalil, F; Atassi, G; Dubois, J; Hanocq, M1
Katenga, EB; Schwalbe, CH; Simmonds, RJ1
Ames, MM; Sanders, ME; Tiede, WS1
Borm, P; Frankhuyzen-Sierevogel, A; Hulshoff, A; Mingels, MJ; Noordhoek, J1
Abel, G; Rutty, CJ1
Ghodrati, F; Lavoie, EJ1

Other Studies

6 other study(ies) available for pentamethylmonomethylolmelamine and altretamine

ArticleYear
Pharmacokinetics and metabolism of hexamethylmelamine in mice after IP administration.
    Cancer chemotherapy and pharmacology, 1986, Volume: 18, Issue:3

    Topics: Algorithms; Altretamine; Animals; Chemical Phenomena; Chemistry; Half-Life; Injections, Intraperitoneal; Kinetics; Male; Mice; Models, Biological; Triazines

1986
The geometry of N-hydroxymethyl compounds. Part 2: Crystal structures of 1-(4-carbethoxyphenyl)-3-hydroxymethyl-3-methyltriazene, N-hydroxymethylpentamethylmelamine and N-hydroxymethylbenzamide.
    Anti-cancer drug design, 1988, Volume: 3, Issue:2

    Topics: Altretamine; Antineoplastic Agents; Benzamides; Molecular Conformation; Triazenes; Triazines

1988
Role of N-methylolpentamethylmelamine in the metabolic activation of hexamethylmelamine.
    Cancer research, 1983, Volume: 43, Issue:2

    Topics: Altretamine; Animals; Carbon Radioisotopes; Cytochrome P-450 Enzyme System; Kinetics; Male; Microsomes, Liver; NADP; Protein Binding; Proteins; Rats; Rats, Inbred Strains; Triazines

1983
Rapid formation of N-hydroxymethylpentamethylmelamine by mitochondria from rat small intestinal epithelium.
    Life sciences, 1983, Nov-21, Volume: 33, Issue:21

    Topics: Altretamine; Animals; Biotransformation; Cytochrome P-450 Enzyme System; Epithelium; Intestine, Small; Kinetics; Male; Microsomes; Mitochondria; Rats; Rats, Inbred Strains; Triazines

1983
In vitro cytotoxicity of the methylmelamines.
    Chemico-biological interactions, 1980, Volume: 29, Issue:2

    Topics: Altretamine; Animals; Cell Survival; Cells, Cultured; Formaldehyde; Mice; Neoplasms, Experimental; Semicarbazides; Triazines

1980
Prodrugs of hydroxymethylpentamethylmelamine: a principal active metabolite of the antineoplastic agent hexamethylmelamine.
    Drug design and discovery, 1994, Volume: 11, Issue:2

    Topics: Altretamine; Antineoplastic Agents; Drug Stability; Half-Life; Hydrolysis; Prodrugs; Solubility

1994