penicillin n has been researched along with 5-(2-aminoadipyl)cysteinylvaline in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (56.25) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 3 (18.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hönlinger, C; Kubicek, CP | 1 |
| Demain, AL; Jensen, SE; Shen, YQ; Westlake, DW; Wolfe, S | 1 |
| López-Nieto, MJ; Martín, JF; Ramos, FR | 1 |
| Demain, AL; Shen, YQ; Wolfe, S | 1 |
| Jensen, SE; Westlake, DW; Wolfe, S | 2 |
| Abraham, EP; Baldwin, JE; John, EM; White, RL | 1 |
| Baldwin, JE; Demain, AL; Sawada, Y; Singh, PD; Solomon, NA | 1 |
| Berry, DM; Demain, AL; Duckworth, DC; Huckstep, LL; Kupka, J; Neuss, N; Queener, SW | 1 |
| Aharonowitz, Y; Argaman, A; Cohen, G; Mislovati, M; Schreiber, R | 1 |
| Baldwin, JE; Clifton, IJ; Hajdu, J; Hensgens, CM; Roach, PL; Schofield, CJ; Shibata, N | 1 |
| Bovenberg, R; Mulder, C; Nielsen, J; Theilgaard, H; van Den Berg, M | 1 |
| Lundberg, M; Morokuma, K; Siegbahn, PE | 1 |
| Cao, YX; Chen, Y; Lu, H; Qiao, B; Yuan, YJ | 1 |
| Adlington, RM; Baldwin, JE; Clifton, IJ; Ge, W; Rutledge, PJ | 1 |
| Boer, R; Bovenberg, R; de Boer, TE; Faddeeva, A; Hensbergen, P; Koopman, J; Mariën, J; Roelofs, D; Suring, W; Timmermans, MJ; van Leeuwen, H; van Straalen, NM | 1 |
16 other study(ies) available for penicillin n and 5-(2-aminoadipyl)cysteinylvaline
| Article | Year |
|---|---|
Regulation of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine and isopenicillin N biosynthesis in Penicillium chrysogenum by the alpha-aminoadipate pool size.
Topics: 2-Aminoadipic Acid; Amino Acid Sequence; Amino Acids, Dicarboxylic; Molecular Sequence Data; Oligopeptides; Penicillins; Penicillium; Penicillium chrysogenum; Time Factors | 1989 |
Further studies on the cyclization of the unnatural tripeptide delta-(D-alpha-aminoadipyl)-L-cysteinyl-D-valine to penicillin N.
Topics: Cephalosporins; Cyclization; Oligopeptides; Penicillins; Streptomyces | 1986 |
Isopenicillin N synthetase of Penicillium chrysogenum, an enzyme that converts delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine to isopenicillin N.
Topics: Biotransformation; Culture Media; Cyclization; Enzymes; Hydrogen-Ion Concentration; Kinetics; Molecular Weight; Oligopeptides; Oxidoreductases; Penicillins; Penicillium; Penicillium chrysogenum; Temperature | 1985 |
Enzymatic conversion of the unnatural tripeptide delta-(D-alpha-aminoadipyl)-L-cysteinyl-D-valine to beta-lactam antibiotics.
Topics: Acremonium; Anti-Bacterial Agents; beta-Lactams; Enzymes; Intramolecular Transferases; Isomerases; Oligopeptides; Oxidoreductases; Penicillin-Binding Proteins; Penicillinase; Penicillins | 1984 |
Partial purification and characterization of isopenicillin N epimerase activity from Streptomyces clavuligerus.
Topics: Amino Acid Isomerases; Bacterial Proteins; Chromatography, Gel; Chromatography, Ion Exchange; Coenzymes; Cyclization; Electrophoresis, Polyacrylamide Gel; Hydroxylamine; Hydroxylamines; Molecular Weight; Oligopeptides; Penicillins; Pyridoxal Phosphate; Streptomyces; Temperature | 1983 |
Stoichiometry of oxygen consumption in the biosynthesis of isopenicillin from a tripeptide.
Topics: Cell-Free System; Electrodes; Magnetic Resonance Spectroscopy; Methods; Oligopeptides; Oxygen Consumption; Penicillins | 1982 |
High performance liquid chromatographic assay of cyclization activity in cell-free systems from Streptomyces clavuligerus.
Topics: Anti-Bacterial Agents; Cell-Free System; Chromatography, High Pressure Liquid; Oligopeptides; Penicillins; Streptomyces | 1982 |
Cell-free cyclization of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine to isopenicillin N.
Topics: Acremonium; Bacterial Proteins; Cell-Free System; Culture Media; Cyclization; Fermentation; Ferrous Compounds; Oligopeptides; Penicillins; Polyethylene Glycols | 1980 |
High performance liquid chromatography (HPLC) of natural products V. The use of HPLC in the cell-free biosynthetic conversion of alpha-aminoadipyl-cysteinyl-valine (LLD) into isopenicillin N.
Topics: Acremonium; Cell-Free System; Chromatography, High Pressure Liquid; Oligopeptides; Penicillins | 1982 |
The thioredoxin system of Penicillium chrysogenum and its possible role in penicillin biosynthesis.
Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; Disulfides; Genes, Fungal; Molecular Sequence Data; NADH, NADPH Oxidoreductases; Oligopeptides; Oxidation-Reduction; Penicillins; Penicillium chrysogenum; Sequence Homology, Amino Acid; Substrate Specificity; Thioredoxins | 1994 |
Structure of isopenicillin N synthase complexed with substrate and the mechanism of penicillin formation.
Topics: Binding Sites; Crystallography, X-Ray; Ferrous Compounds; Hydrogen Bonding; Models, Molecular; Oligopeptides; Oxidoreductases; Oxygen; Penicillins; Protein Conformation | 1997 |
Quantitative analysis of Penicillium chrysogenum Wis54-1255 transformants overexpressing the penicillin biosynthetic genes.
Topics: Culture Media; Disulfides; Enzyme Induction; Fungal Proteins; Gene Expression Regulation, Bacterial; Glucose; Glutathione; Glutathione Disulfide; Industrial Microbiology; Oligopeptides; Oxidoreductases; Penicillin V; Penicillins; Penicillium chrysogenum; Peptide Synthases; Sulfhydryl Compounds; Transformation, Genetic | 2001 |
The mechanism for isopenicillin N synthase from density-functional modeling highlights the similarities with other enzymes in the 2-His-1-carboxylate family.
Topics: Catalysis; Catalytic Domain; Enzymes; Models, Chemical; Models, Molecular; Oligopeptides; Oxidoreductases; Penicillins; Thermodynamics; Thiazolidines | 2008 |
Comparison of the secondary metabolites in Penicillium chrysogenum between pilot and industrial penicillin G fermentations.
Topics: Chromatography, Liquid; Fermentation; Oligopeptides; Penicillin G; Penicillins; Penicillium chrysogenum; Tandem Mass Spectrometry | 2011 |
Isopenicillin N synthase binds δ-(L-α-aminoadipoyl)-L-cysteinyl-D-thia-allo-isoleucine through both sulfur atoms.
Topics: Binding Sites; Biochemistry; Crystallography, X-Ray; Fungal Proteins; Hydrophobic and Hydrophilic Interactions; Iron; Isoleucine; Models, Molecular; Oligopeptides; Oxidation-Reduction; Oxidoreductases; Oxygen; Penicillins; Protein Binding; Substrate Specificity; Sulfur; Valine | 2011 |
A functional isopenicillin N synthase in an animal genome.
Topics: Amino Acid Sequence; Animals; Catalytic Domain; Genome, Insect; Insect Proteins; Insecta; Models, Molecular; Molecular Sequence Data; Oligopeptides; Oxidoreductases; Penicillins; Phylogeny; Sequence Analysis, DNA | 2013 |