penicillin g has been researched along with p-aminohippuric acid in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (22.22) | 18.7374 |
| 1990's | 7 (19.44) | 18.2507 |
| 2000's | 17 (47.22) | 29.6817 |
| 2010's | 4 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Endou, H; Hosoyamada, M; Kanai, Y; Sekine, T | 1 |
| Chan, BS; Lu, R; Schuster, VL | 1 |
| Nezu, J; Oku, A; Sai, Y; Sakamoto, K; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H | 1 |
| Cha, SH; Endou, H; Kanai, Y; Kojima, R; Kusuhara, H; Sekine, T; Sugiyama, Y; Tsuda, M; Utsunomiya-Tate, N | 1 |
| Cha, SH; Endou, H; Fukushima , JI; Goya, T; Kanai, Y; Kobayashi, Y; Sekine, T | 1 |
| Cha, SH; Endou, H; Hosoyamada, M; Jung, KY; Kim, DK; Narikawa, S; Sekine, T; Takeda, M; Tojo, A; Yoo, BS | 1 |
| Endou, H; Hasegawa, M; Ito, K; Kusuhara, H; Sugiyama, D; Sugiyama, Y; Ueda, S | 1 |
| Endou, H; Kusuhara, H; Nagata, Y; Sugiyama, Y | 1 |
| Babu, E; Cha, SH; Endou, H; Enomoto, A; Kobayashi, Y; Narikawa, S; Sakthisekaran, D; Sekine, T; Takeda, M; Tojo, A | 1 |
| Deguchi, T; Hosoya, K; Kang, YS; Mori, S; Ohtsuki, S; Takanaga, H; Terasaki, T | 1 |
| Hori, S; Kikkawa, T; Mori, S; Ohtsuki, S; Otagiri, M; Takanaga, H; Terasaki, T | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Walker, WG; Whelton, A | 1 |
| Bostwick, EF; Hewitt, WR; Hook, JB; Wagner, PA | 1 |
| Apap, R; Manis, J | 1 |
| Buchanan, N; Eyberg, C; Koornhof, HJ; Robinson, R | 1 |
| Bailie, MD; Bond, JT; Hook, JB | 1 |
| Takeda, K; Tamai, I; Terasaki, T; Tsuji, A | 1 |
| Nierenberg, DW | 1 |
| Nakashima, E; Takanosu, K; Tamai, I; Terasaki, T; Tsuji, A | 1 |
| Hirozane, K; Inui, K; Nagai, J; Takano, M; Yasuhara, M | 1 |
| Apiwattanakul, N; Endou, H; Jariyawat, S; Kanai, Y; Sekine, T; Sophasan, S; Takeda, M | 1 |
| Kikuchi, R; Kusuhara, H; Sugiyama, D; Sugiyama, Y | 1 |
| KUNIN, CM | 1 |
| Deguchi, T; Endou, H; Kusuhara, H; Otagiri, M; Sugiyama, Y; Takadate, A | 1 |
| Adachi-Akahane, S; Endou, H; Hasegawa, M; Imaoka, T; Kusuhara, H; Morita, N; Sugiyama, Y | 1 |
| Deguchi, T; Kouno, Y; Otagiri, M; Takadate, A; Terasaki, T | 1 |
| Schnabolk, GW; Sweet, DH; Youngblood, GL | 1 |
| Hasegawa, M; Kondo, T; Kusuhara, H; Nakazawa, H; Nozaki, Y; Okano, T; Shiroyanagi, Y; Sugiyama, Y | 1 |
| Adachi, M; Adachi, Y; Hu, Z; Kamiyama, E; Kondo, T; Kusuhara, H; Maeda, K; Nakazawa, H; Okano, T; Schuetz, JD; Shiroyanagi, Y; Sugiyama, D; Sugiyama, Y; Yamada, A | 1 |
| Akanuma, S; Hosoya, K; Makihara, A; Mori, S; Tachikawa, M; Terasaki, T; Tomi, M; Tsujikawa, Y; Yoneyama, D | 1 |
| Choi, MK; Han, YH; Kim, H; Shim, CK; Song, IS | 1 |
| Fujita, T; Horita, S; Ikeda, Y; Kondo, T; Kumagai, Y; Kusuhara, H; Maeda, K; Nakayama, H; Sugiyama, Y; Tanabe, K; Tian, Y | 1 |
1 review(s) available for penicillin g and p-aminohippuric acid
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for penicillin g and p-aminohippuric acid
| Article | Year |
|---|---|
Inhibitory effects of p-aminohippurate and probenecid on the renal clearance of adefovir and benzylpenicillin as probe drugs for organic anion transporter (OAT) 1 and OAT3 in humans.
Topics: Adenine; Adult; Drug Interactions; HEK293 Cells; Humans; In Vitro Techniques; Kidney; Male; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Organophosphonates; p-Aminohippuric Acid; Penicillin G; Probenecid; Young Adult | 2014 |
34 other study(ies) available for penicillin g and p-aminohippuric acid
| Article | Year |
|---|---|
Molecular cloning and functional expression of a multispecific organic anion transporter from human kidney.
Topics: Amino Acid Sequence; Animals; Anion Transport Proteins; Blotting, Northern; Carrier Proteins; Cloning, Molecular; Female; Humans; In Situ Hybridization, Fluorescence; Kidney; Molecular Sequence Data; Oocytes; Xenopus laevis | 1999 |
Cloning of the human kidney PAH transporter: narrow substrate specificity and regulation by protein kinase C.
Topics: Amino Acid Sequence; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 11; Cloning, Molecular; DNA, Complementary; HeLa Cells; Humans; Kidney; Molecular Sequence Data; p-Aminohippuric Acid; Protein Kinase C; Rats; Substrate Specificity; Tissue Distribution | 1999 |
Novel membrane transporter OCTN1 mediates multispecific, bidirectional, and pH-dependent transport of organic cations.
Topics: Animals; Biological Transport, Active; Carrier Proteins; Cell Line; Gene Expression; Humans; Hydrogen-Ion Concentration; Membrane Potentials; Membrane Proteins; Membrane Transport Proteins; Oocytes; Organic Cation Transport Proteins; Quinidine; RNA, Messenger; Symporters; Tetraethylammonium Compounds; Xenopus laevis | 1999 |
Molecular cloning and characterization of a new multispecific organic anion transporter from rat brain.
Topics: Amino Acid Sequence; Animals; Brain; Carrier Proteins; Cloning, Molecular; DNA, Complementary; Estrone; Molecular Sequence Data; Ochratoxins; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Amino Acid; Xenopus laevis | 1999 |
Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney.
Topics: Amino Acid Sequence; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 11; Cloning, Molecular; Gene Library; Humans; Kidney Tubules, Proximal; Molecular Sequence Data; Oocytes; Organic Anion Transporters, Sodium-Independent; Sequence Homology, Amino Acid; Tissue Distribution; Transfection; Xenopus laevis | 2001 |
Characterization of ochratoxin A transport by human organic anion transporters.
Topics: Animals; Biological Transport; Cell Line; Humans; Kidney Tubules, Proximal; Mice; Mice, Transgenic; Ochratoxins; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Potassium | 2001 |
Functional involvement of rat organic anion transporter 3 (rOat3; Slc22a8) in the renal uptake of organic anions.
Topics: Algorithms; Animals; Anions; Blotting, Western; Fluorescent Antibody Technique; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Kidney; Kinetics; Ligands; LLC-PK1 Cells; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Penicillin G; Penicillins; Pravastatin; Rats; Rats, Sprague-Dawley; Swine | 2002 |
Expression and functional characterization of rat organic anion transporter 3 (rOat3) in the choroid plexus.
Topics: Animals; Choroid Plexus; Cimetidine; Enzyme Inhibitors; Male; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Penicillin G; Penicillins; Rats; Rats, Sprague-Dawley | 2002 |
Role of human organic anion transporter 4 in the transport of ochratoxin A.
Topics: Animals; Biological Transport, Active; Cells, Cultured; Humans; Immunohistochemistry; Kidney; Liver-Specific Organic Anion Transporter 1; Mice; Ochratoxins; Organic Anion Transporters, Sodium-Independent; Piroxicam; Probenecid; Recombinant Proteins; Transfection | 2002 |
Rat organic anion transporter 3 (rOAT3) is responsible for brain-to-blood efflux of homovanillic acid at the abluminal membrane of brain capillary endothelial cells.
Topics: Animals; Blood-Brain Barrier; Cimetidine; Convulsants; Endothelium, Vascular; Enzyme Inhibitors; Homovanillic Acid; Indican; Male; Oocytes; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Penicillin G; Rats; Rats, Wistar; Transfection; Tritium; Xenopus laevis | 2003 |
Mouse reduced in osteosclerosis transporter functions as an organic anion transporter 3 and is localized at abluminal membrane of blood-brain barrier.
Topics: Animals; Biological Transport; Blood-Brain Barrier; Capillaries; Disease Models, Animal; Estrone; Male; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Osteosclerosis; Penicillin G; RNA, Messenger | 2004 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
An approach to the interpretation of drug concentrations in the kidney.
Topics: Aminohippuric Acids; Ampicillin; Animals; Dogs; Glomerular Filtration Rate; Hydrogen-Ion Concentration; Inulin; Kidney; Kidney Cortex; Kidney Medulla; Kidney Tubules, Proximal; Nephrons; p-Aminohippuric Acid; Penicillin G; Pharmaceutical Preparations | 1978 |
Transport ontogeny and selective substrate stimulation as models for identification of multiple renal organic anion transport systems.
Topics: 4-Aminobenzoic Acid; Aging; Animals; Animals, Newborn; Anions; Aspirin; Biological Transport, Active; Chenodeoxycholic Acid; In Vitro Techniques; Iodipamide; Kidney Cortex; p-Aminohippuric Acid; Penicillin G; Phenolsulfonphthalein; Rabbits; Sulfisoxazole; Uric Acid | 1977 |
Intestinal organic anion transport, glutathione transferase and aryl hydrocarbon hydroxylase activity: effect of dioxin.
Topics: Animals; Anions; Aryl Hydrocarbon Hydroxylases; Biological Transport; Dioxins; Glutathione Transferase; Intestinal Mucosa; Intestines; Male; p-Aminohippuric Acid; Penicillin G; Phlorhizin; Polychlorinated Dibenzodioxins; Rats | 1979 |
Penicillin pharmacokinetics in kwashiorkor.
Topics: Half-Life; Humans; Infant; Kidney; Kidney Tubules; Kinetics; Kwashiorkor; p-Aminohippuric Acid; Penicillin G | 1979 |
Maturation of renal organic acid transport in vivo: substrate stimulation by penicillin.
Topics: Aminohippuric Acids; Animals; Animals, Newborn; Biological Transport; Biological Transport, Active; Blood Proteins; Dogs; In Vitro Techniques; Inulin; Kidney; p-Aminohippuric Acid; Penicillin G; Protein Binding; Stimulation, Chemical | 1976 |
In vivo evidence for carrier-mediated uptake of beta-lactam antibiotics through organic anion transport systems in rat kidney and liver.
Topics: Animals; Anti-Bacterial Agents; Biological Transport; Dose-Response Relationship, Drug; Kidney; Liver; Male; p-Aminohippuric Acid; Penicillin G; Probenecid; Rats; Rats, Inbred Strains | 1990 |
Drug inhibition of penicillin tubular secretion: concordance between in vitro and clinical findings.
Topics: 2,4-Dinitrophenol; Animals; Binding, Competitive; Biological Transport, Active; Dinitrophenols; In Vitro Techniques; Indomethacin; Kidney; Kinetics; Methotrexate; p-Aminohippuric Acid; Penicillin G; Rabbits | 1987 |
Kinetic evidence for a common transport route of benzylpenicillin and probenecid by freshly prepared hepatocytes in rats. Influence of sodium ion, organic anions, amino acids and peptides on benzylpenicillin uptake.
Topics: Amino Acids; Animals; Anions; Cattle; Cephalosporins; In Vitro Techniques; Kinetics; Liver; Male; p-Aminohippuric Acid; Penicillin G; Peptides; Probenecid; Rats; Rats, Inbred Strains; Serum Albumin; Serum Albumin, Bovine; Sodium; Taurocholic Acid | 1986 |
Specificity of p-aminohippurate transport system in the OK kidney epithelial cell line.
Topics: Animals; Biological Transport; Cefazolin; Cefotiam; Cell Line; Cephalosporins; Epithelium; Kidney; Opossums; p-Aminohippuric Acid; Penicillin G; Penicillins | 1995 |
The interaction and transport of beta-lactam antibiotics with the cloned rat renal organic anion transporter 1.
Topics: Animals; Anion Transport Proteins; Anti-Bacterial Agents; Biological Transport; Carrier Proteins; Cell Survival; Cephaloridine; Cephalosporins; In Vitro Techniques; Kidney; Kinetics; Oocytes; p-Aminohippuric Acid; Penicillin G; Rats; Recombinant Proteins; Xenopus laevis | 1999 |
Contribution of organic anion transporter 3 (Slc22a8) to the elimination of p-aminohippuric acid and benzylpenicillin across the blood-brain barrier.
Topics: Animals; Biological Transport; Blood-Brain Barrier; Blotting, Western; Brain; Capillaries; Cimetidine; Drug Interactions; Enzyme Inhibitors; Immunohistochemistry; Male; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Penicillin G; Pravastatin; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Tritium | 2003 |
INHIBITORS OF PENICILLIN BINDING TO SERUM PROTEINS.
Topics: Acetazolamide; Animals; Anti-Bacterial Agents; Antibiotics, Antitubercular; Antimetabolites; Aspirin; Benzoates; Biguanides; Blood Proteins; Carbon Isotopes; Chlorothiazide; Diuretics; Ethacrynic Acid; Guanidines; Oxazoles; p-Aminohippuric Acid; Penicillin G; Penicillin V; Penicillins; Pharmacology; Phenylbutazone; Probenecid; Rabbits; Research; Salicylates; Sulfinpyrazone; Sulfonamides; Tolbutamide | 1965 |
Characterization of uremic toxin transport by organic anion transporters in the kidney.
Topics: Animals; DNA, Complementary; GABA Modulators; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney Tubules, Proximal; LLC-PK1 Cells; Male; Organ Culture Techniques; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Penicillin G; Pravastatin; Rats; Rats, Sprague-Dawley; Swine; Toxins, Biological; Transfection; Uremia | 2004 |
The renal-specific transporter mediates facilitative transport of organic anions at the brush border membrane of mouse renal tubules.
Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Anions; Brain; Carbon Radioisotopes; Carrier Proteins; Cell Line; Cloning, Molecular; Convulsants; Herbicides; Humans; Ion Transport; Kidney Tubules, Proximal; LLC-PK1 Cells; Male; Membrane Proteins; Mice; Microvilli; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Penicillin G; Rabbits; Rats; Swine; Transfection; Tritium; Uric Acid | 2004 |
Differential contributions of rOat1 (Slc22a6) and rOat3 (Slc22a8) to the in vivo renal uptake of uremic toxins in rats.
Topics: Animals; Biological Transport; Carbon Radioisotopes; Estrone; Furans; Hippurates; Indican; Indoleacetic Acids; Kidney; Male; Metabolic Clearance Rate; Organic Anion Transport Protein 1; Organic Cation Transport Proteins; p-Aminohippuric Acid; Penicillin G; Propionates; Rats; Rats, Wistar; Serum; Tritium | 2005 |
Transport of estrone sulfate by the novel organic anion transporter Oat6 (Slc22a20).
Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Biological Transport; Calcium Channel Blockers; CHO Cells; Cricetinae; Cyclooxygenase Inhibitors; Estrone; GABA Modulators; Herbicides; Mice; Ochratoxins; Organic Anion Transporters; p-Aminohippuric Acid; Penicillin G; Probenecid; Salicylates; Transfection; Uricosuric Agents; Xenopus laevis | 2006 |
Characterization of the uptake of organic anion transporter (OAT) 1 and OAT3 substrates by human kidney slices.
Topics: 2,4-Dichlorophenoxyacetic Acid; Biological Transport, Active; Cell Line; Dehydroepiandrosterone Sulfate; Estrone; Humans; In Vitro Techniques; Kidney; Kinetics; Methotrexate; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Penicillin G; RNA, Messenger; Transfection | 2007 |
Multiple human isoforms of drug transporters contribute to the hepatic and renal transport of olmesartan, a selective antagonist of the angiotensin II AT1-receptor.
Topics: Adenosine Triphosphate; Angiotensin II Type 1 Receptor Blockers; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line; Dogs; Dose-Response Relationship, Drug; Estrone; Female; Hepatocytes; Humans; Imidazoles; In Vitro Techniques; Kidney; Kinetics; Liver; Liver-Specific Organic Anion Transporter 1; Membrane Transport Proteins; Mice; Mice, Knockout; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Olmesartan Medoxomil; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Penicillin G; Probenecid; Prodrugs; Protein Binding; Protein Isoforms; Sincalide; Solute Carrier Organic Anion Transporter Family Member 1B3; Tetrazoles; Transfection | 2007 |
Roles of inner blood-retinal barrier organic anion transporter 3 in the vitreous/retina-to-blood efflux transport of p-aminohippuric acid, benzylpenicillin, and 6-mercaptopurine.
Topics: Animals; Anions; Anti-Infective Agents; Antimetabolites, Antineoplastic; Biological Transport, Active; Blood-Retinal Barrier; Blotting, Western; Capillaries; Data Interpretation, Statistical; Immunohistochemistry; Male; Mercaptopurine; Microdialysis; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Penicillin G; Rats; Rats, Wistar; Regional Blood Flow; Retinal Vessels; Reverse Transcriptase Polymerase Chain Reaction; Vitreous Body | 2009 |
Involvement of Mrp2/MRP2 in the species different excretion route of benzylpenicillin between rat and human.
Topics: Adenosine Triphosphate; Animals; Anti-Bacterial Agents; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Cyclosporine; Dogs; Estradiol; Flow Cytometry; Humans; Male; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; p-Aminohippuric Acid; Penicillin G; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Rhodamines; Species Specificity; Substrate Specificity; Taurocholic Acid; Transport Vesicles | 2009 |