penicillin g has been researched along with methotrexate in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (20.69) | 18.7374 |
| 1990's | 4 (13.79) | 18.2507 |
| 2000's | 10 (34.48) | 29.6817 |
| 2010's | 9 (31.03) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chan, BS; Lu, R; Schuster, VL | 1 |
| Cha, SH; Endou, H; Kanai, Y; Kojima, R; Kusuhara, H; Sekine, T; Sugiyama, Y; Tsuda, M; Utsunomiya-Tate, N | 1 |
| Cha, SH; Endou, H; Fukushima , JI; Goya, T; Kanai, Y; Kobayashi, Y; Sekine, T | 1 |
| Cha, SH; Endou, H; Hosoyamada, M; Khamdang, S; Kimura, H; Narikawa, S; Sekine, T; Takeda, M | 1 |
| Hori, S; Kikkawa, T; Mori, S; Ohtsuki, S; Otagiri, M; Takanaga, H; Terasaki, T | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Anderson, KC; Kellogg, GE; Sarkar, A | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Fent, K; Popovic, M; Smital, T; Zaja, R | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Cooney, LM; Newman, JH; Waycott, S | 1 |
| Brasch, H; Iven, H | 1 |
| Nierenberg, DW | 1 |
| Hunt, DE; Pittillo, RF | 1 |
| Freeman, AI; Gaeta, JF; Sinks, LF; Wang, JJ | 1 |
| Evans, EA | 1 |
| Berger, FM; Fukui, G; Ludwig, BJ; Margolin, S | 1 |
| Pakulska, W | 1 |
| Kang, YS; Kikkawa, T; Mori, S; Ohtsuki, S; Takanaga, H; Terasaki, T | 1 |
| Hasegawa, M; Kondo, T; Kusuhara, H; Nakazawa, H; Nozaki, Y; Okano, T; Shiroyanagi, Y; Sugiyama, Y | 1 |
| Agarwal, S; Elmquist, WF; Li, L | 1 |
1 review(s) available for penicillin g and methotrexate
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
28 other study(ies) available for penicillin g and methotrexate
| Article | Year |
|---|---|
Cloning of the human kidney PAH transporter: narrow substrate specificity and regulation by protein kinase C.
Topics: Amino Acid Sequence; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 11; Cloning, Molecular; DNA, Complementary; HeLa Cells; Humans; Kidney; Molecular Sequence Data; p-Aminohippuric Acid; Protein Kinase C; Rats; Substrate Specificity; Tissue Distribution | 1999 |
Molecular cloning and characterization of a new multispecific organic anion transporter from rat brain.
Topics: Amino Acid Sequence; Animals; Brain; Carrier Proteins; Cloning, Molecular; DNA, Complementary; Estrone; Molecular Sequence Data; Ochratoxins; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Amino Acid; Xenopus laevis | 1999 |
Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney.
Topics: Amino Acid Sequence; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 11; Cloning, Molecular; Gene Library; Humans; Kidney Tubules, Proximal; Molecular Sequence Data; Oocytes; Organic Anion Transporters, Sodium-Independent; Sequence Homology, Amino Acid; Tissue Distribution; Transfection; Xenopus laevis | 2001 |
Characterization of methotrexate transport and its drug interactions with human organic anion transporters.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Cells, Cultured; Humans; Indomethacin; Kinetics; Liver-Specific Organic Anion Transporter 1; Methotrexate; Mice; Mice, Transgenic; Nerve Tissue Proteins; Organic Anion Transporters, Sodium-Independent; Phenylbutazone; Potassium Channels; Potassium Channels, Tandem Pore Domain; Probenecid | 2002 |
Mouse reduced in osteosclerosis transporter functions as an organic anion transporter 3 and is localized at abluminal membrane of blood-brain barrier.
Topics: Animals; Biological Transport; Blood-Brain Barrier; Capillaries; Disease Models, Animal; Estrone; Male; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Osteosclerosis; Penicillin G; RNA, Messenger | 2004 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Computational analysis of structure-based interactions and ligand properties can predict efflux effects on antibiotics.
Topics: Anti-Bacterial Agents; beta-Lactams; Computational Biology; Drug Resistance, Bacterial; Hydrophobic and Hydrophilic Interactions; Ligands; Membrane Transport Proteins; Microbial Sensitivity Tests; Models, Molecular; Protein Binding; Protein Conformation; Quantitative Structure-Activity Relationship; Regression Analysis; Thermodynamics | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Molecular characterization of zebrafish Oatp1d1 (Slco1d1), a novel organic anion-transporting polypeptide.
Topics: Animals; Evolution, Molecular; Glycosylation; Gonadal Steroid Hormones; HEK293 Cells; Humans; Ion Transport; Organic Anion Transporters; Protein Multimerization; Zebrafish; Zebrafish Proteins | 2013 |
Arthritis due to Listeria monocytogenes.
Topics: Ampicillin; Arthritis, Infectious; Arthritis, Rheumatoid; Cephalothin; Drug Hypersensitivity; Female; Gentamicins; Humans; Knee Joint; Listeria monocytogenes; Listeriosis; Methotrexate; Middle Aged; Penicillin G | 1979 |
Cephalosporins increase the renal clearance of methotrexate and 7-hydroxymethotrexate in rabbits.
Topics: Animals; Antineoplastic Agents; Ceftazidime; Cephalosporins; Folic Acid Antagonists; Kidney; Male; Methotrexate; Penicillin G; Rabbits; Time Factors | 1990 |
Drug inhibition of penicillin tubular secretion: concordance between in vitro and clinical findings.
Topics: 2,4-Dinitrophenol; Animals; Binding, Competitive; Biological Transport, Active; Dinitrophenols; In Vitro Techniques; Indomethacin; Kidney; Kinetics; Methotrexate; p-Aminohippuric Acid; Penicillin G; Rabbits | 1987 |
Killing of cells in bacterial colonies.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Azaserine; Chloramphenicol; Enterococcus faecalis; Escherichia coli; Fluorouracil; Kinetics; Methotrexate; Nitroso Compounds; Penicillin G; Urea | 1967 |
Unusual complications of pentamidine in the treatment of Pneumocystis carinii pneumonia.
Topics: Acute Kidney Injury; Amidines; Autopsy; Blister; Blood Glucose; Child, Preschool; Cytoplasm; Epithelium; Female; Humans; Hyperglycemia; Leukemia, Lymphoid; Methotrexate; Nitrogen; Penicillin G; Pneumonia, Pneumocystis; Stevens-Johnson Syndrome; Sulfonic Acids; Uremia | 1970 |
Control of self-irradiation decomposition of tritium-labelled compounds at high specific activity.
Topics: Alcohols; Drug Stability; Ethanol; Folic Acid; Formates; Histidine; Leucine; Methotrexate; Nucleosides; Penicillin G; Radiation-Protective Agents; Thymidine; Tritium; Tyrosine; Uridine | 1966 |
Selective suppression of penicillin hypersensitivity by certain phenoxy propanediols.
Topics: Animals; Antigen-Antibody Reactions; Chlorphenesin; Cyclophosphamide; Drug Hypersensitivity; Guinea Pigs; Mercaptopurine; Methotrexate; Muscles; Passive Cutaneous Anaphylaxis; Penicillin G; Serum Albumin, Bovine; Thioguanine | 1967 |
[The effect of benzylpenicillin and doxycycline on toxicity and antineoplastic action of cyclophosphamide and methotrexate in mice].
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Doxycycline; Drug Interactions; Lethal Dose 50; Leukemia L1210; Male; Methotrexate; Mice; Penicillin G | 1992 |
Organic anion transporter 3 is involved in the brain-to-blood efflux transport of thiopurine nucleobase analogs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites, Antineoplastic; Biological Transport; Blood-Brain Barrier; Indomethacin; Male; Mercaptopurine; Methotrexate; Oocytes; Organic Anion Transporters, Sodium-Independent; Penicillin G; Rats; Rats, Wistar; Thioguanine; Xenopus laevis | 2004 |
Characterization of the uptake of organic anion transporter (OAT) 1 and OAT3 substrates by human kidney slices.
Topics: 2,4-Dichlorophenoxyacetic Acid; Biological Transport, Active; Cell Line; Dehydroepiandrosterone Sulfate; Estrone; Humans; In Vitro Techniques; Kidney; Kinetics; Methotrexate; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Penicillin G; RNA, Messenger; Transfection | 2007 |
Brain efflux index to investigate the influence of active efflux on brain distribution of pemetrexed and methotrexate.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Blood-Brain Barrier; Capillary Permeability; Folic Acid Antagonists; Glutamates; Guanine; Half-Life; Male; Methotrexate; Mice; Mice, Inbred C57BL; Mice, Knockout; Microinjections; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Organic Anion Transporters, Sodium-Independent; Pemetrexed; Penicillin G; Probenecid | 2013 |