Page last updated: 2024-08-17

penicillin g and levofloxacin

penicillin g has been researched along with levofloxacin in 62 studies

Research

Studies (62)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (3.23)	18.2507
2000's	39 (62.90)	29.6817
2010's	19 (30.65)	24.3611
2020's	2 (3.23)	2.80

Authors

Authors	Studies
Nezu, J; Oku, A; Sai, Y; Sakamoto, K; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H	1
Inagaki, H; Kawakami, K; Kawato, HC; Matsuhashi, N; Miyauchi, RN; Miyauchi, S; Ohki, H; Takahashi, H; Takemura, M	1
Clark, NC; Donlan, RM; Dumas, N; Jensen, B; Kohlerschmidt, D; Limberger, RJ; McDougal, LK; Musser, KA; Patel, JB; Shin, DH; Thompson, J; Weigel, LM; Zhu, W	1
Abbanat, D; Bush, K; Flamm, RK; Foleno, BD; Goldschmidt, RM; Macielag, MJ; Paget, SD; Webb, GC; Wira, E	1
Fiett, J; Gniadkowski, M; Grzesiowski, P; Hryniewicz, W; Izdebski, R; Sadowy, E	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Appelbaum, PC; Bogdanovich, T; Clark, C; Dewasse, B; Ednie, L; McGhee, P; Smith, K	1
Jorgensen, JH; Moore, MR; Ressner, RA	1
Danese, P; DeVito, J; Franceschi, F; Lawrence, L; Sutcliffe, J	1
Baquero, F; Cantón, R; de la Pedrosa, EG; Galán, JC; Morosini, MI; Reinert, RR; Ruiz-Garbajosa, P; van der Linden, M	1
Appelbaum, PC; Ednie, LM; Hawser, S; Lociuro, S; Smith, K	1
Beckius, ML; Fraser, SL; Galloway, RL; Griffith, ME; Hospenthal, DR; Mende, K; Miller, RS; Murray, CK; Pimentel, G; Ressner, RA	1
Chang, KY; Ho, YH; Hsieh, YC; Hsueh, PR; Huang, LM; Huang, YC; Lin, HC	1
Brickner, SJ; Duignan, J; Finegan, S; Girard, D; Huband, MD; Le, PT; Maloney, M; Schafer, J; Stone, GG; Wade, SK; Zaniewski, RP	1
Lombardo, F; Obach, RS; Waters, NJ	1
Benton, BM; Draghi, DC; Krause, KM; Pillar, C; Sahm, DF; Thornsberry, C	1
Brown, SD; Critchley, IA; Jacobs, MR; Janjic, N; Tillotson, GS; Traczewski, MM	1
Benton, BM; Debabov, DV; Difuntorum, S; Krause, KM; Renelli, M; Wu, TX	1
Amsler, KM; Bush, K; Davies, TA; Jacobs, MR; Shang, W	1
Biek, D; Ge, Y; Sahm, DF; Talbot, GH	1
Hsueh, PR; Huang, YT; Liao, CH; Lin, HY; Liu, CY; Yen, LC	1
Aguilar, L; Biek, D; Fenoll, A; Giménez, MJ; Granizo, JJ; Robledo, O; Tarragó, D	1
Arakawa, Y; Kimura, K; Nagano, N; Nagano, Y; Tamai, K; Yanagisawa, H	1
Bell, JM; Biedenbach, DJ; Jones, RN; Sader, HS; Turnidge, JD	1
Fritsche, TR; Jones, RN; Sader, HS	1
Appelbaum, PC; Ednie, LM; Kosowska-Shick, K; McGhee, P	1
Iwata, S; Murayama, SY; Nakayama, E; Sakata, H; Seki, C; Sunakawa, K; Sunaoshi, K; Ubukata, K	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Hafkin, B; Hoban, DJ; Kaplan, N; Karlowsky, JA; Zhanel, GG	1
Brunner, LS; Haas, W; Lee, JC; Morris, TW; Pillar, CM; Zurenko, GE	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Arhin, FF; Draghi, DC; Moeck, G; Parr, TR; Pillar, CM; Sahm, DF	1
Distèche-Nguyen, M; Gerards, T; Luxen, A; Miguet, L; Pasha, FA; Thomas, A; Zervosen, A	1
Appelbaum, PC; Beachel, L; Clark, C; Dewasse, B; Kosowska-Shick, KM; McGhee, P; Nagai, K	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Cai, L; Gilbert, GL; Kong, F; Oftadeh, S; Xiao, M; Xu, X; Zhou, F	1
Amsler, KM; Bush, K; Foleno, BD; He, W; Lynch, AS; Macielag, MJ; Morrow, BJ	1
Blango, MG; Mulvey, MA	1
Bajaksouzian, S; Biek, D; Critchley, IA; Good, CE; Jacobs, MR; Jones, RN; Sader, HS; Windau, AR	1
Ardanuy, C; Brito-Avô, A; Gonçalo-Marques, J; Liñares, J; Morais, A; Pires, R; Rolo, D; Santos-Sanches, I	1
Dal-Ré, R; García-de-Lomas, J; García-Delafuente, C; Iriarte, V; Martín-Herrero, JE; Mazón, A; Pérez-Trallero, E; Robles, P	1
Bulens, SN; Fosheim, GE; Limbago, BM; McDougal, LK; Nicholson, A; Patel, JB; Shearer, JE; Summers, AO	1
Biedenbach, DJ; Castanheira, M; Jones, RN	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Inagaki, H; Kitamura, T; Komoriya, S; Kuroyanagi, J; Miyauchi, RN; Nagamochi, M; Odagiri, T; Sugimoto, Y; Takahashi, H	1
Bellman, K; Knegtel, RM; Settimo, L	1
Hu, X; Lin, W; Liu, D; Niu, S; Proksch, P; Shao, Z	1
Bao, Y; Huang, X; Lan, S; Wang, T; Zhang, X; Zhu, S	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Ashenden, S; Bender, A; Cokol, M; Karakoc, I; Kuru, N; Mason, DJ; Meral, S; Stott, I; Weinstein, ZB	1
Gao, F; Huang, G; Xiao, J	1
Amada, H; Endo, M; Hitaka, K; Kamitani, M; Masuko, A; Mihara, Y; Mima, M; Ohtake, N; Sugiyama, H; Takata, I; Takeuchi, T; Tamura, Y; Tanaka-Yamamoto, N; Ushiyama, F; Wada, R	1
Chiba, A; Harada, S; Hasegawa, M; Kaneko, A; Kobayashi, I; Koyama, H; Matsuzaki, K; Omika, K; Sasaki, J; Sato, Y	1
Coleman, EJ; Mandell, GL	1
Hashido, H; Ishigo, S; Iwata, I; Matsubara, S; Matsukawa, Y; Mikamo, H; Sawamura, H; Suematsu, H; Tamaya, T	1
Bercion, R; Carricajo, A; Celard, M; Chomarat, M; Croizé, J; Delubac, F; Fèvre, D; Frédénucci, I; Fuhrmann, C; Helfre, M; Lelièvre, H; Letouzey, MN; Mandjee, A; Marthelet, P; Meley, R; Perrier-Gros-Claude, JD; Ros, A; Roure, C; Smati, S; Thierry, J; Tous, J	1
Doganay, M; Esel, D; Sumerkan, B	1
Itoh, Y; Kikuchi, K; Nakanishi, K; Nakao, S; Ohsaki, Y; Osanai, S; Saito, K; Sato, M; Tachibana, M; Takahashi, T; Toyoshima, E	1
Hasegawa, M; Kobayashi, I; Matsuzaki, K; Sato, Y; Shikano, M; Watabe, E; Yamanaka, N; Yoshimori, K	1
Iwashima, A; Kiguchi, T; Sato, K; Yamaguchi, M	1
Xie, H; Yuan, HL; Zhang, W; Zheng, YY	1
Canut, A; Ibar-Bariain, M; Isla, A; Rodríguez-Gascón, A; Sanz-Moreno, JC; Solinís, MÁ	1

Reviews

2 review(s) available for penicillin g and levofloxacin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Current scenario of tetrazole hybrids for antibacterial activity. European journal of medicinal chemistry, 2019, Dec-15, Volume: 184 Topics: Anti-Bacterial Agents; Bacteria; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Tetrazoles	2019

Trials

1 trial(s) available for penicillin g and levofloxacin

Article	Year
In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:9 Topics: Anti-Bacterial Agents; Cephalosporins; Enterobacteriaceae; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Skin Diseases, Bacterial; Staphylococcus	2008

Article

Year

In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections.

Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:9

Topics: Anti-Bacterial Agents; Cephalosporins; Enterobacteriaceae; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Skin Diseases, Bacterial; Staphylococcus

2008

Other Studies

59 other study(ies) available for penicillin g and levofloxacin

Article	Year
Novel membrane transporter OCTN1 mediates multispecific, bidirectional, and pH-dependent transport of organic cations. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:2 Topics: Animals; Biological Transport, Active; Carrier Proteins; Cell Line; Gene Expression; Humans; Hydrogen-Ion Concentration; Membrane Potentials; Membrane Proteins; Membrane Transport Proteins; Oocytes; Organic Cation Transport Proteins; Quinidine; RNA, Messenger; Symporters; Tetraethylammonium Compounds; Xenopus laevis	1999
Synthesis and structure-activity relationships of 5-amino-6-fluoro-1-[(1R,2S)-2-fluorocyclopropan-1-yl]-8-methylquinolonecarboxylic acid antibacterials having fluorinated 7-[(3R)-3-(1-aminocyclopropan-1-yl)pyrrolidin-1-yl] substituents. Journal of medicinal chemistry, 2003, Mar-13, Volume: 46, Issue:6 Topics: Anti-Bacterial Agents; Cyclopropanes; Drug Resistance, Bacterial; Gram-Positive Bacteria; Microbial Sensitivity Tests; Quinolones; Stereoisomerism; Structure-Activity Relationship	2003
High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:1 Topics: Acetamides; Aminoglycosides; Biofilms; Catheters, Indwelling; Chloramphenicol; Drug Resistance, Multiple, Bacterial; Enterococcus faecalis; Enterococcus faecium; Female; Fluoroquinolones; Humans; Linezolid; Macrolides; Microbial Sensitivity Tests; Micrococcus; Middle Aged; Morganella morganii; Oxazolidinones; Penicillins; Pseudomonas aeruginosa; Rifampin; Staphylococcus aureus; Tetracyclines; Trimethoprim, Sulfamethoxazole Drug Combination; Urinary Catheterization; Vancomycin; Vancomycin Resistance	2007
In vitro antibacterial activity of the pyrrolopyrazolyl-substituted oxazolidinone RWJ-416457. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:1 Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Bacterial; Enterococcus; Linezolid; Microbial Sensitivity Tests; Molecular Structure; Oxazolidinones; Staphylococcus; Streptococcus	2007
Clonal diversity and resistance mechanisms in tetracycline-nonsusceptible Streptococcus pneumoniae isolates in Poland. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4 Topics: Bacterial Proteins; Cell Lineage; DNA Transposable Elements; Genetic Variation; Poland; Streptococcus pneumoniae; Tetracycline; Tetracycline Resistance	2007
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
In vitro activity of DC-159a, a new broad-spectrum fluoroquinolone, compared with that of other agents against drug-susceptible and -resistant pneumococci. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:1 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Culture Media; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Mutation; Streptococcus pneumoniae	2008
Activity of the Diaminopyrimidine AR-709 against recently collected multidrug-resistant isolates of invasive Streptococcus pneumoniae from North America. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:3 Topics: Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Humans; Indoles; Microbial Sensitivity Tests; North America; Pneumococcal Infections; Pyrimidines; Streptococcus pneumoniae; Tetrahydrofolate Dehydrogenase	2008
In vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:5 Topics: Anti-Infective Agents; Bacteria; Community-Acquired Infections; Cross Infection; Enterococcus; Humans; Methicillin Resistance; Microbial Sensitivity Tests; Molecular Structure; Oxazolidinones; Respiratory System; Staphylococcus; Staphylococcus aureus; Streptococcus; Streptococcus pneumoniae	2008
Polyclonal population structure of Streptococcus pneumoniae isolates in Spain carrying mef and mef plus erm(B). Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:6 Topics: Anti-Bacterial Agents; Bacterial Proteins; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Erythromycin; Humans; Membrane Proteins; Methyltransferases; Microbial Sensitivity Tests; Sequence Analysis, DNA; Serotyping; Spain; Streptococcus pneumoniae	2008
Antistreptococcal activity of AR-709 compared to that of other agents. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:6 Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Pyrimidines; Streptococcus pneumoniae; Streptococcus pyogenes; Tetrahydrofolate Dehydrogenase; Trimethoprim, Sulfamethoxazole Drug Combination	2008
Antimicrobial susceptibilities of geographically diverse clinical human isolates of Leptospira. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8 Topics: Ampicillin; Anti-Bacterial Agents; Azithromycin; Cefepime; Cefotaxime; Ceftriaxone; Cephalosporins; Ciprofloxacin; Egypt; Hawaii; Humans; Leptospira; Leptospirosis; Levofloxacin; Microbial Sensitivity Tests; Nicaragua; Ofloxacin; Tetracycline; Thailand	2008
Clonal spread of highly beta-lactam-resistant Streptococcus pneumoniae isolates in Taiwan. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:6 Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactams; Genotype; Humans; Microbial Sensitivity Tests; Pneumococcal Infections; Serotyping; Streptococcus pneumoniae; Taiwan	2008
In vitro antibacterial activity of CE-156811, a novel analog derived from hygromycin A. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:7 Topics: Acetamides; Anti-Bacterial Agents; Cinnamates; Dioxoles; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Hygromycin B; In Vitro Techniques; Linezolid; Microbial Sensitivity Tests; Molecular Structure; Oxazolidinones	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Comparative surveillance study of telavancin activity against recently collected gram-positive clinical isolates from across the United States. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:7 Topics: Aminoglycosides; Anti-Bacterial Agents; Drug Resistance, Bacterial; Enterococcus; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Lipoglycopeptides; Microbial Sensitivity Tests; Prospective Studies; Staphylococcus aureus; Streptococcus; Streptococcus pneumoniae; United States	2008
Prevalence of serotype 19A Streptococcus pneumoniae among isolates from U.S. children in 2005-2006 and activity of faropenem. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:7 Topics: Adolescent; Anti-Bacterial Agents; beta-Lactams; Child; Child, Preschool; Drug Resistance, Bacterial; Humans; Infant; Microbial Sensitivity Tests; Phenotype; Pneumococcal Infections; Serotyping; Streptococcus pneumoniae; United States	2008
In vitro activity of telavancin against resistant gram-positive bacteria. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:7 Topics: Aminoglycosides; Anti-Bacterial Agents; Drug Resistance, Bacterial; Enterococcus; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; In Vitro Techniques; Lipoglycopeptides; Methicillin Resistance; Microbial Sensitivity Tests; Staphylococcus; Streptococcus	2008
In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:9 Topics: Anti-Bacterial Agents; Ceftaroline; Cephalosporins; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; United States	2008
Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:9 Topics: Anti-Bacterial Agents; Bacteria, Anaerobic; Bacteroides fragilis; Bacteroides Infections; Blood; Carbapenems; Cross Infection; Drug Resistance, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Taiwan	2008
In vitro activity of ceftaroline against Streptococcus pneumoniae isolates exhibiting resistance to penicillin, amoxicillin, and cefotaxime. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:11 Topics: Amoxicillin; Anti-Bacterial Agents; Cefotaxime; Ceftaroline; Cephalosporin Resistance; Cephalosporins; Drug Resistance, Multiple, Bacterial; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Penicillin Resistance; Penicillins; Pneumococcal Infections; Streptococcus pneumoniae	2008
Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:12 Topics: Aminoacyltransferases; Anti-Bacterial Agents; Bacterial Proteins; Female; Genetic Heterogeneity; Humans; Infant, Newborn; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillin Resistance; Penicillin-Binding Proteins; Penicillins; Phylogeny; Sequence Analysis, DNA; Streptococcus agalactiae	2008
Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:3 Topics: Anti-Bacterial Agents; Asia; Drug Resistance, Bacterial; Europe; Gram-Positive Bacteria; Humans; Latin America; Microbial Sensitivity Tests; North America; Pacific Ocean; Quality Control; Teicoplanin; Vancomycin	2009
Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:5 Topics: Anti-Bacterial Agents; Enterococcus faecalis; Europe; Gram-Positive Bacterial Infections; Gram-Positive Cocci; Hospitalization; Humans; Methicillin; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Pyrimidines; Staphylococcus aureus; Streptococcus; United States	2009
Comparative antipneumococcal activities of sulopenem and other drugs. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:6 Topics: Anti-Bacterial Agents; beta-Lactam Resistance; Lactams; Microbial Sensitivity Tests; Penicillin-Binding Proteins; Streptococcus pneumoniae	2009
Capsular type and antibiotic resistance in Streptococcus agalactiae isolates from patients, ranging from newborns to the elderly, with invasive infections. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:6 Topics: Adolescent; Adult; Aged; Bacterial Capsules; Child; Child, Preschool; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Infant; Infant, Newborn; Levofloxacin; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Polymerase Chain Reaction; Streptococcus agalactiae	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:8 Topics: Anti-Bacterial Agents; Benzofurans; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Enterobacteriaceae; Enterococcus; Microbial Sensitivity Tests; Moraxella catarrhalis; Pyrones; Staphylococcal Infections; Staphylococcus; Staphylococcus aureus; Staphylococcus epidermidis; Streptococcus pneumoniae	2009
Besifloxacin, a novel fluoroquinolone, has broad-spectrum in vitro activity against aerobic and anaerobic bacteria. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:8 Topics: Anti-Bacterial Agents; Azepines; Bacteria, Anaerobic; Drug Resistance, Bacterial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:11 Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Enterococcus faecium; Glycopeptides; Gram-Positive Bacteria; Humans; Lipoglycopeptides; Microbial Sensitivity Tests; Staphylococcus aureus; Streptococcus	2009
Discovery of new inhibitors of resistant Streptococcus pneumoniae penicillin binding protein (PBP) 2x by structure-based virtual screening. Journal of medicinal chemistry, 2009, Oct-08, Volume: 52, Issue:19 Topics: Computational Biology; Computer Simulation; Drug Discovery; Drug Evaluation, Preclinical; Drug Resistance, Bacterial; Ligands; Penicillin-Binding Proteins; Protein Binding; Streptococcus pneumoniae; Structure-Activity Relationship	2009
In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1 Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Macrolides; Microbial Sensitivity Tests; Penicillin G; Streptococcus pneumoniae; Streptococcus pyogenes; Triazoles	2010
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Distribution of serotypes, genotypes, and resistance determinants among macrolide-resistant Streptococcus pneumoniae isolates. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:3 Topics: Anti-Bacterial Agents; Bacterial Proteins; Child, Preschool; DNA Transposable Elements; Drug Resistance, Bacterial; Erythromycin; Genotype; Humans; Macrolides; Microbial Sensitivity Tests; New South Wales; Pneumococcal Infections; Serotyping; Streptococcus pneumoniae	2010
In vitro antibacterial activities of JNJ-Q2, a new broad-spectrum fluoroquinolone. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:5 Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Design; Drug Resistance, Bacterial; Escherichia coli; Fluoroquinolones; Methicillin-Resistant Staphylococcus aureus; Streptococcus pneumoniae	2010
Persistence of uropathogenic Escherichia coli in the face of multiple antibiotics. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:5 Topics: Animals; Anti-Bacterial Agents; Biofilms; Cell Membrane Permeability; Cells, Cultured; Drug Resistance, Bacterial; Endosomes; Escherichia coli; Escherichia coli Infections; Female; Humans; Mice; Mice, Inbred CBA; Microbial Sensitivity Tests; Recurrence; Urinary Bladder; Urinary Tract Infections; Urothelium	2010
Activity of ceftaroline against recent emerging serotypes of Streptococcus pneumoniae in the United States. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:6 Topics: Anti-Bacterial Agents; Ceftaroline; Cephalosporins; Communicable Diseases, Emerging; Drug Resistance, Multiple, Bacterial; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Pneumococcal Infections; Serotyping; Streptococcus pneumoniae; United States	2010
Emergence of ciprofloxacin-nonsusceptible Streptococcus pyogenes isolates from healthy children and pediatric patients in Portugal. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:6 Topics: Amino Acid Substitution; Anti-Bacterial Agents; Antigens, Bacterial; Bacterial Outer Membrane Proteins; Bacterial Typing Techniques; Carrier Proteins; Child; Ciprofloxacin; Drug Resistance, Bacterial; Humans; Molecular Epidemiology; Norfloxacin; Point Mutation; Portugal; Streptococcal Infections; Streptococcus pyogenes	2010
Antimicrobial resistance among respiratory pathogens in Spain: latest data and changes over 11 years (1996-1997 to 2006-2007). Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:7 Topics: Ampicillin; Anti-Bacterial Agents; Cefotaxime; Erythromycin; Haemophilus influenzae; Lincosamides; Macrolides; Microbial Sensitivity Tests; Penicillins; Respiratory Tract Infections; Spain; Streptococcus pneumoniae; Streptococcus pyogenes; Streptogramin B	2010
Emergence of resistance among USA300 methicillin-resistant Staphylococcus aureus isolates causing invasive disease in the United States. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:9 Topics: Anti-Bacterial Agents; Clindamycin; Doxycycline; Drug Resistance, Multiple; Gentamicins; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Mupirocin; Plasmids; Polymerase Chain Reaction; Tetracycline; Trimethoprim, Sulfamethoxazole Drug Combination; United States	2010
Determination of CEM-101 activity tested against clinical isolates of Neisseria meningitidis from a worldwide collection. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:9 Topics: Anti-Bacterial Agents; Azithromycin; Ceftriaxone; Ciprofloxacin; Humans; Ketolides; Macrolides; Microbial Sensitivity Tests; Minocycline; Neisseria meningitidis; Penicillins; Rifampin; Sulfamethoxazole; Triazoles; Trimethoprim	2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Design, synthesis, and biological evaluations of novel 7-[7-amino-7-methyl-5-azaspiro[2.4]heptan-5-yl]-8-methoxyquinolines with potent antibacterial activity against respiratory pathogens. Journal of medicinal chemistry, 2013, Mar-14, Volume: 56, Issue:5 Topics: Animals; Anti-Bacterial Agents; Drug Design; Fluoroquinolones; Haemophilus influenzae; Male; Mice; Microbial Sensitivity Tests; Quinolones; Rats; Respiratory Tract Infections; Spiro Compounds; Staphylococcus aureus; Streptococcus pneumoniae	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Spiromastixones A-O, antibacterial chlorodepsidones from a deep-sea-derived Spiromastix sp. fungus. Journal of natural products, 2014, Apr-25, Volume: 77, Issue:4 Topics: Anti-Bacterial Agents; Depsides; Enterococcus faecalis; Fungi; Gram-Positive Bacteria; Heterocyclic Compounds, 3-Ring; Hydrocarbons, Chlorinated; Lactones; Methicillin; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oceans and Seas; Staphylococcus aureus; Structure-Activity Relationship; Vancomycin	2014
Synthesis and biological evaluation of levofloxacin core-based derivatives with potent antibacterial activity against resistant Gram-positive pathogens. Bioorganic & medicinal chemistry letters, 2015, Sep-15, Volume: 25, Issue:18 Topics: Anti-Bacterial Agents; Dose-Response Relationship, Drug; Levofloxacin; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Structure; Penicillin Resistance; Streptococcus pneumoniae; Streptococcus pyogenes; Structure-Activity Relationship	2015
Prediction of Antibiotic Interactions Using Descriptors Derived from Molecular Structure. Journal of medicinal chemistry, 2017, 05-11, Volume: 60, Issue:9 Topics: Anti-Bacterial Agents; Drug Interactions; Molecular Structure	2017
Lead optimization of 8-(methylamino)-2-oxo-1,2-dihydroquinolines as bacterial type II topoisomerase inhibitors. Bioorganic & medicinal chemistry, 2020, 11-15, Volume: 28, Issue:22 Topics: Anti-Bacterial Agents; Cell Survival; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Hep G2 Cells; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Quinolines; Streptococcus pneumoniae; Structure-Activity Relationship; Topoisomerase II Inhibitors; Transcriptional Regulator ERG; Vancomycin-Resistant Enterococci	2020
[In vitro activities of levofloxacin and other antibiotics against fresh clinical isolates]. The Japanese journal of antibiotics, 1999, Volume: 52, Issue:9 Topics: Ampicillin; Anti-Infective Agents; Bacteria; Bacterial Infections; Cefaclor; Cefpodoxime; Ceftizoxime; Cephalosporins; Ciprofloxacin; Drug Resistance, Microbial; Humans; Levofloxacin; Methicillin; Ofloxacin; Penicillin G; Penicillin Resistance; Penicillins	1999
Activities of antimicrobial agents against intracellular pneumococci. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:9 Topics: Anti-Bacterial Agents; Aza Compounds; Azithromycin; Fluoroquinolones; Gentamicins; Humans; Ketolides; Levofloxacin; Macrolides; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Penicillin G; Quinolines; Rifampin; Streptococcus pneumoniae; Tumor Cells, Cultured	2000
[The frequency of Streptococcus pneumoniae strains and sensitivity surveillance for several antibiotics in Gifu Prefecture]. The Japanese journal of antibiotics, 2000, Volume: 53, Issue:12 Topics: Amoxicillin; Anti-Bacterial Agents; Cefaclor; Cefdinir; Cefixime; Cefmenoxime; Cefpodoxime; Ceftizoxime; Cephalosporins; Ciprofloxacin; Clarithromycin; Clindamycin; Drug Resistance, Microbial; Fluoroquinolones; Humans; Imipenem; Japan; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Minocycline; Naphthyridines; Ofloxacin; Penicillin G; Penicillins; Streptococcus pneumoniae; Thienamycins	2000
Comparative in vitro activity of penicillin G, levofloxacin, moxifloxacin, telithromycin, pristinamycin, quinupristin-dalfopristin and linezolid against ofloxacin-intermediate and -resistant Streptococcus pneumoniae. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2002, Volume: 8, Issue:10 Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Drug Resistance, Bacterial; Fluoroquinolones; Ketolides; Lactams; Levofloxacin; Linezolid; Macrolides; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Oxazolidinones; Penicillin G; Pristinamycin; Quinolines; Streptococcus pneumoniae; Virginiamycin	2002
Antimicrobial susceptibilities of 40 isolates of Bacillus anthracis isolated in Turkey. International journal of antimicrobial agents, 2003, Volume: 22, Issue:1 Topics: Anthrax; Anti-Bacterial Agents; Bacillus anthracis; Ciprofloxacin; Doxycycline; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Penicillin G; Penicillins; Turkey	2003
Alterations in penicillin binding protein gene of Streptococcus pneumoniae and their correlation with susceptibility patterns. International journal of antimicrobial agents, 2003, Volume: 22, Issue:2 Topics: Aminoacyltransferases; Anti-Bacterial Agents; Azithromycin; Bacterial Proteins; Carrier Proteins; Clarithromycin; Drug Resistance, Bacterial; Genes, Bacterial; Hexosyltransferases; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Muramoylpentapeptide Carboxypeptidase; Mutation; Ofloxacin; Penicillin G; Penicillin Resistance; Penicillin-Binding Proteins; Peptidyl Transferases; Pneumococcal Infections; Streptococcus pneumoniae; Thienamycins	2003
[Susceptibility of major pathogens of acute pharyngitis and tonsillitis to levofloxacin and other oral antimicrobial drugs]. The Japanese journal of antibiotics, 2003, Volume: 56, Issue:3 Topics: Acute Disease; Ampicillin; Anti-Infective Agents; Azithromycin; Cefdinir; Cefpodoxime; Ceftizoxime; Cephalosporins; Clarithromycin; Enterobacteriaceae; Haemophilus influenzae; Humans; Levofloxacin; Ofloxacin; Penicillin G; Pharyngitis; Streptococcus pneumoniae; Streptococcus pyogenes; Tonsillitis	2003
[Isolation-frequency and antibiotic susceptibility of Streptococcus pneumoniae, Haemophilus influenzae, and Pseudomonas aeruginosa isolated in regional core hospitals in the Nagaoka district of Niigata Prefecture (changes for 3 years)]. The Japanese journal of antibiotics, 2004, Volume: 57, Issue:1 Topics: Anti-Infective Agents; Carbapenems; Ciprofloxacin; Drug Resistance, Bacterial; Haemophilus influenzae; Hospitals, Urban; Humans; Japan; Levofloxacin; Ofloxacin; Penicillin G; Pseudomonas aeruginosa; Streptococcus pneumoniae; Time Factors	2004
Two cases of human cutaneous anthrax with massive tissue damage, severe edema, and slight injury to the liver. International journal of dermatology, 2018, Volume: 57, Issue:3 Topics: Adult; Anthrax; Biopsy, Needle; Blister; Drug Therapy, Combination; Edema; Humans; Immunohistochemistry; Levofloxacin; Liver; Male; Methylprednisolone; Middle Aged; Penicillin G; Prognosis; Risk Assessment; Skin Diseases, Bacterial; Soft Tissue Injuries; Treatment Outcome; Upper Extremity	2018
Pharmacokinetic/pharmacodynamic evaluation of the antimicrobial therapy of pneumococcal invasive disease in adults in post-PCV13 vaccine period in Madrid, Spain. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2021, Volume: 40, Issue:10 Topics: Adult; Anti-Bacterial Agents; Cefotaxime; Clinical Trials as Topic; Humans; Levofloxacin; Penicillin G; Pneumococcal Infections; Pneumococcal Vaccines; Spain; Streptococcus pneumoniae	2021