penicillin g has been researched along with imipenem, anhydrous in 103 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (11.65) | 18.7374 |
| 1990's | 12 (11.65) | 18.2507 |
| 2000's | 47 (45.63) | 29.6817 |
| 2010's | 30 (29.13) | 24.3611 |
| 2020's | 2 (1.94) | 2.80 |
| Authors | Studies |
|---|---|
| Hannah, J; Johnson, CR; Wagner, AF; Walton, E | 1 |
| Cattoir, V; Nordmann, P; Poirel, L; Soares, A; Soussy, CJ | 1 |
| Bonnet, R; Chanal, C; Delmas, J; Lesens, O; Robin, F; Schweitzer, C; Tournilhac, O | 1 |
| Aubert, D; Naas, T; Nordmann, P; Ozcan, A | 1 |
| Cattoir, V; Corvec, S; Drugeon, H; Faccone, D; Galas, M; Mugnier, P; Nordmann, P; Pasteran, F; Petroni, A; Poirel, L; Rapoport, M | 1 |
| Ayala, JA; Casellas, JM; Di Conza, J; Ghiglione, B; Gutkind, G; Power, P; Radice, M; Rodríguez, MM | 1 |
| Kwon, DH; Lu, CD | 1 |
| Amicosante, G; Caporale, B; Celenza, G; Docquier, JD; Mezzatesta, M; Pellegrini, C; Perilli, M; Rossolini, GM; Stefani, S | 1 |
| Miriagou, V; Papagiannitsis, CC; Tzelepi, E; Tzouvelekis, LS | 1 |
| Bonnet, R; Brebion, A; Constantin, JM; Delmas, J; Dubois, D; Robin, F | 1 |
| Girlich, D; Leclercq, R; Naas, T; Nordmann, P | 1 |
| Bonnet, R; Neuwirth, C; Robin, F; Siebor, E | 1 |
| Courvalin, P; Decré, D; Høiby, EA; Meziane-Cherif, D; Périchon, B | 1 |
| Carattoli, A; Cattoir, V; Figueiredo, S; Nordmann, P; Poirel, L | 1 |
| Courvalin, P; Dupêchez, M; Galimand, M; Lambert, T; Meziane-Cherif, D | 1 |
| Bouallegue, O; Mansour, W; Nordmann, P; Poirel, L | 1 |
| Bonnet, R; Caniça, M; Ferreira, E; Manageiro, V; Mendonça, N; Robin, F; Salgado, MJ | 1 |
| Limansky, AS; Marchiaro, P; Mussi, MA; Pasteran, F; Tomatis, PE; Viale, AM; Vila, AJ | 1 |
| Doi, Y; Nordmann, P; Paterson, DL; Poirel, L | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Docquier, JD; Frère, JM; Rossolini, GM; Stoczko, M | 1 |
| Bauernfeind, A; Keuleyan, E; Markovska, R; Queenan, AM; Rasshofer, R; Schneider, I | 1 |
| Castanheira, M; Samuelsen, Ø; Spencer, J; Walsh, TR | 1 |
| Biek, D; Ge, Y; Sahm, DF; Talbot, GH | 1 |
| Hsueh, PR; Huang, YT; Liao, CH; Lin, HY; Liu, CY; Yen, LC | 1 |
| Jarlier, V; Mayer, C; Petrella, S; Renard, M; Sougakoff, W; Ziental-Gelus, N | 1 |
| Albertí, S; Beceiro, A; Bou, G; Garau, M; Gutiérrez, O; Juan, C; Oliver, A; Pérez, JL | 1 |
| Arpin, C; Bezian, MC; Coulange, L; Demarthe, F; Dubois, V; Minarini, LA; Nordmann, P; Poirel, L; Quentin, C | 1 |
| Kanamori, M; Kirikae, T; Kitao, T; Miyoshi-Akiyama, T; Morita, K; Okazaki, M; Sekiguchi, J; Watanabe, N | 1 |
| Nordmann, P; Plésiat, P; Poirel, L; Rodriguez-Martinez, JM | 1 |
| Kotsakis, SD; Miriagou, V; Tzelepi, E; Tzouvelekis, LS; Whichard, JM; Zioga, A | 1 |
| Appelbaum, PC; Kosowska-Shick, K; McGhee, P | 1 |
| Nordmann, P; Poirel, L; Rodríguez-Martínez, JM | 1 |
| Bonnet, R; Brisabois, A; Cloeckaert, A; Doublet, B; Fabre, L; Granier, SA; Robin, F; Weill, FX | 1 |
| Appelbaum, PC; Ednie, LM; Kosowska-Shick, K; McGhee, P | 1 |
| Kotsakis, SD; Miriagou, V; Papagiannitsis, CC; Tzelepi, E; Tzouvelekis, LS | 1 |
| Ghori, S; Griggs, DJ; Johnson, MM; Mott, A; Peake, L; Piddock, LJ | 1 |
| Brunner, LS; Haas, W; Lee, JC; Morris, TW; Pillar, CM; Zurenko, GE | 1 |
| Bauernfeind, A; Keuleyan, E; Markova, B; Markovska, R; Queenan, AM; Schneider, I | 1 |
| De Luca, F; Delmarcelle, M; Docquier, JD; Dubus, A; Frère, JM; Nacoulma, OG; Rossolini, GM; Simporé, J; Zeba, B | 1 |
| Distèche-Nguyen, M; Gerards, T; Luxen, A; Miguet, L; Pasha, FA; Thomas, A; Zervosen, A | 1 |
| Cho, HS; Giske, CG; Lee, K; Sundman, K; Toleman, MA; Walsh, TR; Yong, D | 1 |
| Higgins, PG; Lehmann, M; Nordmann, P; Poirel, L; Seifert, H | 1 |
| Arnold, I; Bizzini, A; Entenza, JM; Erni, B; Michielin, O; Moreillon, P | 1 |
| Bonnet, R; Casin, I; Doublet, B; Fabre, L; Le Fleche, A; Robin, F; Weill, FX | 1 |
| De Luca, F; Docquier, JD; Ide, L; Nordmann, P; Poirel, L; Rossolini, GM; Verlinde, A | 1 |
| Bush, K; Flamm, R; Queenan, AM; Shang, W | 1 |
| Girlich, D; Nordmann, P; Poirel, L | 2 |
| Aggoune-Khinache, N; Bonnet, R; Delmas, J; Naim, M; Robin, F | 1 |
| Fortineau, N; Nordmann, P; Poirel, L; Rodriguez-Martinez, JM | 1 |
| Kotsakis, SD; Legakis, NJ; Miriagou, V; Papagiannitsis, CC; Tzelepi, E; Tzouvelekis, LS | 1 |
| Campos, J; Carrilero, L; Escudero, JA; Garcia-Cobos, S; Gonzalez-Zorn, B; Gutierrez, B; Hidalgo, L; San Millan, A | 1 |
| De Luca, F; Docquier, JD; Fosse, T; Giraud-Morin, C; Rossolini, GM | 1 |
| Bajaksouzian, S; Biek, D; Critchley, IA; Good, CE; Jacobs, MR; Jones, RN; Sader, HS; Windau, AR | 1 |
| Al Naiemi, N; Debets-Ossenkopp, YJ; Nordmann, P; Poirel, L; Rodríguez-Martínez, JM | 1 |
| Bent, ZW; Young, GM | 1 |
| Nordmann, P; Poirel, L; Rodríguez-Martínez, JM; Ronco, E | 1 |
| Collins, B; Cotter, PD; Curtis, N; Hill, C; Ross, RP | 1 |
| Kotsakis, SD; Miriagou, V; Tzelepi, E; Tzouvelekis, LS | 1 |
| Borgianni, L; Docquier, JD; Hanson, ND; Prandi, S; Rossolini, GM; Salden, L; Santella, G | 1 |
| Ishii, Y; Matsuzawa, H; Mura, K; Oishi, M; Sakai, H; Shimizu-Ibuka, A; Yamada, S | 1 |
| Chiba, T; Hasegawa, T; Horita, Y; Kremer, L; Kuroishi, R; Lee, Y; Ogawa, K; Onozaki, K; Sato, Y; Takii, T | 1 |
| Angehrn, P; Gmuender, H; Goetschi, E; Hebeisen, P; Hennig, M; Kuhn, B; Luebbers, T; Reindl, P; Ricklin, F; Schmitt-Hoffmann, A | 1 |
| Anderson, KC; Kellogg, GE; Sarkar, A | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Genta-Jouve, G; Greff, S; Massi, L; Perez, T; Thomas, OP; Zubia, M | 1 |
| Bayer, A; Christopeit, T; Guttormsen, Y; Leiros, HK; Lund, BA | 1 |
| Gao, F; Huang, G; Xiao, J | 1 |
| Ba, Z; Chang, L; Gou, S; Li, B; Liu, H; Ni, J; Ouyang, X; Zhang, J; Zhang, T; Zhang, Y; Zhong, C; Zhu, N; Zhu, Y | 1 |
| Barakett, V; Burghoffer, B; Delisle, F; Guidet, B; Lesage, D; Offenstadt, G; Petit, JC; Richard, G; Vergez, P | 1 |
| Milkovich, G; Piazza, CJ | 1 |
| Boisivon, A; Gutmann, L; Pierre, J | 1 |
| Hanano, M; Iga, T; Sawada, Y; Spector, R; Sugiyama, Y; Suzuki, H | 1 |
| Cozens, RM; Markiewicz, Z; Tuomanen, E | 1 |
| Chmel, H; Eng, RH; Munsif, AN; Smith, SM; Yangco, BG | 1 |
| Traub, WH | 2 |
| Douglas, JG; Gould, IM; Hudson, M; Morris, J; Page, G; Reid, TM; Smith, CC | 1 |
| Broholm, KA; Liljedahl, AL; Norrby, SR; Schliamser, SE | 1 |
| Schliamser, SE | 1 |
| Hashizume, T; Matsuhashi, M; Park, W | 1 |
| Geraci, JE; Indrelie, JA; Matsumoto, JY; Washington, JA; Wilson, WR | 1 |
| Bohnhoff, M; Dudek, EJ; Lerner, SA; Stephenson, JD | 1 |
| Bowyer, GW; Cumberland, N | 1 |
| Avila-Campos, MJ; Carvalho, MA; Zelante, F | 1 |
| Akaike, N; Fujimoto, M; Munakata, M | 1 |
| Hatori, T; Matsumoto, T; Miyazaki, H; Takashima, K; Tateda, K; Yamaguchi, K | 1 |
| Choi, YJ; Hong, T; Kish, A; Millett, W; Ndamukong, J; Win, KK | 1 |
| Fiore, M; Perrotta, E | 1 |
| Cuca, GC; Hammond, GG; Leiting, B; Pompliano, DL; Pryor, KD; Toney, JH; Wu, JK | 1 |
| Ben Hassen, A; Ben Redjeb, S; Kamoun, A; Mahjoubi, F | 1 |
| Collatz, E; Gutmann, L; Mainardi, JL; Rybkine, T; Sougakoff, W | 1 |
| Hashido, H; Ishigo, S; Iwata, I; Matsubara, S; Matsukawa, Y; Mikamo, H; Sawamura, H; Suematsu, H; Tamaya, T | 1 |
| Haristoy, X; Labia, R; Lozniewski, A; Mory, F | 1 |
| Fukuda, H; Kawamura, Y | 1 |
| Karasawa, T; Kuriyama, T; Nakagawa, K; Nakamura, S; Yamamoto, E | 1 |
| Rasia, RM; Vila, AJ | 1 |
| Chumjan, W; Hajjar, E; Mahendran, KR; Schulte, A; Suginta, W; Weingart, H; Winterhalter, M | 1 |
| Bebrone, C; Docquier, JD; Favier, A; Ferrer, JL; Frère, JM; Galleni, M; Lassaux, P; Laurent, C; Loisel, E; Sohier, JS; Traoré, DA | 1 |
| Davies, C; Fedarovich, A; Nicholas, RA | 1 |
| Asgeirsson, B; Chakraborty, S; Frère, JM; Minda, R; Rao, BJ; Salaye, L | 1 |
| Ahmadinejad, Z; Emaneini, M; Fazeli, MS; Feizabadi, MM; Jasemi, S; Sadeghpour Heravi, F; Sechi, LA | 1 |
1 review(s) available for penicillin g and imipenem, anhydrous
| Article | Year |
|---|---|
Current scenario of tetrazole hybrids for antibacterial activity.
Topics: Anti-Bacterial Agents; Bacteria; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Tetrazoles | 2019 |
2 trial(s) available for penicillin g and imipenem, anhydrous
| Article | Year |
|---|---|
Seizure propensity with imipenem.
Topics: Aged; Aged, 80 and over; Animals; Cefotaxime; Female; Humans; Imipenem; Male; Mice; Middle Aged; Multicenter Studies as Topic; Penicillin G; Seizures | 1989 |
Imipenem versus standard therapy in the treatment of serious soft tissue infection.
Topics: Abscess; Adult; Aged; Bacteroides; Cellulitis; Clinical Trials as Topic; Cloxacillin; Female; Gram-Negative Bacteria; Humans; Imipenem; Male; Penicillin G; Prospective Studies; Random Allocation; Skin Diseases, Infectious; Staphylococcus; Streptococcus | 1988 |
100 other study(ies) available for penicillin g and imipenem, anhydrous
| Article | Year |
|---|---|
Quaternary heterocyclylamino beta-lactams: a generic alternative to the classical acylamino side chain.
Topics: Anti-Bacterial Agents; Bacteria; beta-Lactams; Chemical Phenomena; Chemistry, Physical; Magnetic Resonance Spectroscopy; Structure-Activity Relationship; Thienamycins | 1982 |
Novel Ambler class A beta-lactamase LAP-1 and its association with the plasmid-mediated quinolone resistance determinant QnrS1.
Topics: Amino Acid Sequence; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Cloning, Molecular; Enterobacter cloacae; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Molecular Sequence Data; Plasmids; Quinolones; Sequence Alignment | 2007 |
Evolution of TEM-type enzymes: biochemical and genetic characterization of two new complex mutant TEM enzymes, TEM-151 and TEM-152, from a single patient.
Topics: beta-Lactamases; Drug Resistance, Bacterial; Escherichia coli; Evolution, Molecular; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation | 2007 |
Chromosome-encoded narrow-spectrum Ambler class A beta-lactamase GIL-1 from Citrobacter gillenii.
Topics: beta-Lactamases; Chromosomes; Chromosomes, Bacterial; Citrobacter; Cloning, Molecular; DNA, Bacterial; Escherichia coli; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Genes, Bacterial; Molecular Sequence Data | 2007 |
Identification of the novel narrow-spectrum beta-lactamase SCO-1 in Acinetobacter spp. from Argentina.
Topics: Acinetobacter; Acinetobacter Infections; Amino Acid Sequence; Anti-Bacterial Agents; Argentina; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Clavulanic Acid; Cloning, Molecular; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Sequence Analysis, DNA | 2007 |
Biochemical characterization of PER-2 and genetic environment of blaPER-2.
Topics: Amino Acid Sequence; Base Sequence; beta-Lactam Resistance; beta-Lactamases; Catalysis; Citrobacter freundii; Conjugation, Genetic; DNA, Bacterial; DNA, Recombinant; Enterobacteriaceae; Genes, Bacterial; Humans; Hydrolysis; Isoelectric Focusing; Kinetics; Mass Spectrometry; Microbial Sensitivity Tests; Molecular Sequence Data; Molecular Weight; Plasmids; Polymerase Chain Reaction; Promoter Regions, Genetic; Protein Conformation; Protein Sorting Signals; Sequence Analysis, DNA | 2007 |
Polyamine effects on antibiotic susceptibility in bacteria.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactams; Drug Resistance, Bacterial; Drug Synergism; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Polyamines; Spermine; Staphylococcus aureus | 2007 |
Identification and characterization of a new metallo-beta-lactamase, IND-5, from a clinical isolate of Chryseobacterium indologenes.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; Carbapenems; Cephalosporins; Chryseobacterium; Flavobacteriaceae Infections; Humans; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillins; Sequence Analysis, DNA | 2007 |
Plasmid-encoded ACC-4, an extended-spectrum cephalosporinase variant from Escherichia coli.
Topics: Anti-Bacterial Agents; Cephalosporinase; Culture Media; DNA Primers; Drug Resistance, Bacterial; Escherichia coli; Kinetics; Models, Molecular; Molecular Sequence Data; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; Spectrophotometry, Ultraviolet | 2007 |
TEM-158 (CMT-9), a new member of the CMT-type extended-spectrum beta-lactamases.
Topics: beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Catalysis; Ceftazidime; Clavulanic Acid; Escherichia coli; Escherichia coli Proteins; Isoenzymes; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Sequence Analysis, DNA | 2007 |
Molecular and biochemical characterization of the chromosome-encoded class A beta-lactamase BCL-1 from Bacillus clausii.
Topics: Amino Acid Sequence; Bacillus; Bacterial Proteins; beta-Lactamases; Chromosome Mapping; Chromosomes, Bacterial; Cloning, Molecular; Microbial Sensitivity Tests; Molecular Sequence Data; Molecular Weight; Sequence Homology, Amino Acid; Substrate Specificity | 2007 |
First occurrence of an IMP metallo-beta-lactamase in Aeromonas caviae: IMP-19 in an isolate from France.
Topics: Aeromonas; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; France; Integrons; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Sequence Analysis, DNA; Substrate Specificity | 2007 |
Genetic and biochemical characterization of CAD-1, a chromosomally encoded new class A penicillinase from Carnobacterium divergens.
Topics: Amino Acid Sequence; beta-Lactams; Chromosomes, Bacterial; Cloning, Molecular; Electrophoresis, Gel, Pulsed-Field; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Infant, Newborn; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillin Resistance; Penicillinase; Sequence Alignment; Sequence Analysis, DNA; Substrate Specificity | 2008 |
Acinetobacter radioresistens as a silent source of carbapenem resistance for Acinetobacter spp.
Topics: Acinetobacter; Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Carbapenems; Culture Media; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Nucleic Acid Hybridization; Plasmids; Polymerase Chain Reaction; Sequence Analysis, DNA; Skin | 2008 |
Genetic and biochemical characterization of OXA-63, a new class D beta-lactamase from Brachyspira pilosicoli BM4442.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Base Sequence; beta-Lactamases; Brachyspira; Cloning, Molecular; Diarrhea; Feces; Gram-Negative Bacterial Infections; Humans; Kinetics; Molecular Sequence Data; Oxacillin; Penicillin Resistance; Sequence Analysis, DNA | 2008 |
Carbapenem-resistant Acinetobacter baumannii isolates from Tunisia producing the OXA-58-like carbapenem-hydrolyzing oxacillinase OXA-97.
Topics: Acinetobacter baumannii; Africa; Bacterial Proteins; beta-Lactamases; Blotting, Southern; Carbapenems; Cross Infection; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Models, Genetic; Molecular Sequence Data; Polymerase Chain Reaction; Tunisia | 2008 |
The Lys234Arg substitution in the enzyme SHV-72 is a determinant for resistance to clavulanic acid inhibition.
Topics: Amino Acid Substitution; Amoxicillin; Anti-Bacterial Agents; Arginine; Aztreonam; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Clavulanic Acid; Computer Simulation; Imipenem; Isoelectric Focusing; Kinetics; Klebsiella pneumoniae; Lysine; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; Penicillins; Protein Conformation; Protein Structure, Tertiary | 2008 |
Biochemical characterization of metallo-beta-lactamase VIM-11 from a Pseudomonas aeruginosa clinical strain.
Topics: beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Binding Sites; Escherichia coli; Humans; Kinetics; Microbial Sensitivity Tests; Models, Molecular; Plasmids; Pseudomonas aeruginosa; Pseudomonas Infections | 2008 |
Characterization of a naturally occurring class D beta-lactamase from Achromobacter xylosoxidans.
Topics: Achromobacter denitrificans; Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Cloning, Molecular; Humans; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Sequence Analysis, DNA | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Functional diversity among metallo-beta-lactamases: characterization of the CAR-1 enzyme of Erwinia carotovora.
Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; beta-Lactamases; Cloning, Molecular; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Genes, Bacterial; Molecular Sequence Data; Open Reading Frames; Pectobacterium carotovorum; Phenotype; Phylogeny; Recombinant Proteins; Sequence Homology, Amino Acid | 2008 |
VIM-15 and VIM-16, two new VIM-2-like metallo-beta-lactamases in Pseudomonas aeruginosa isolates from Bulgaria and Germany.
Topics: Amino Acid Substitution; Bacterial Proteins; beta-Lactamases; Bulgaria; Catalysis; Germany; Hydrolysis; Isoenzymes; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Pseudomonas aeruginosa; Sequence Analysis, DNA | 2008 |
Kinetic characterization of VIM-7, a divergent member of the VIM metallo-beta-lactamase family.
Topics: Acremonium; Bacterial Proteins; beta-Lactamases; Catalysis; Catalytic Domain; Cefepime; Ceftazidime; Cephalosporins; Kinetics; Models, Molecular; Mutation; Penicillinase; Protein Structure, Tertiary; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity | 2008 |
In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States.
Topics: Anti-Bacterial Agents; Ceftaroline; Cephalosporins; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; United States | 2008 |
Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems.
Topics: Anti-Bacterial Agents; Bacteria, Anaerobic; Bacteroides fragilis; Bacteroides Infections; Blood; Carbapenems; Cross Infection; Drug Resistance, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Taiwan | 2008 |
Genetic and structural insights into the dissemination potential of the extremely broad-spectrum class A beta-lactamase KPC-2 identified in an Escherichia coli strain and an Enterobacter cloacae strain isolated from the same patient in France.
Topics: Aged; Base Sequence; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Catalytic Domain; Cephalosporin Resistance; Crystallography, X-Ray; DNA Primers; DNA, Bacterial; Enterobacter cloacae; Enterobacteriaceae Infections; Escherichia coli; Escherichia coli Infections; France; Genes, Bacterial; Humans; Imipenem; Kinetics; Male; Models, Molecular; Mutation | 2008 |
Characterization of the new metallo-beta-lactamase VIM-13 and its integron-borne gene from a Pseudomonas aeruginosa clinical isolate in Spain.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; beta-Lactam Resistance; beta-Lactamases; Cloning, Molecular; DNA Primers; DNA, Bacterial; Genes, Bacterial; Genetic Variation; Humans; Imipenem; Integrons; Kinetics; Meropenem; Molecular Sequence Data; Phylogeny; Pseudomonas aeruginosa; Pseudomonas Infections; Recombinant Proteins; Sequence Homology, Amino Acid; Spain; Thienamycins | 2008 |
Molecular and biochemical characterization of SHV-56, a novel inhibitor-resistant beta-lactamase from Klebsiella pneumoniae.
Topics: Aged; Amino Acid Substitution; Base Sequence; beta-Lactam Resistance; beta-Lactamases; DNA Primers; DNA, Bacterial; Female; Genes, Bacterial; Humans; Isoelectric Point; Kinetics; Klebsiella Infections; Klebsiella pneumoniae; Molecular Sequence Data; Mutagenesis, Insertional; Recombinant Proteins | 2008 |
KHM-1, a novel plasmid-mediated metallo-beta-lactamase from a Citrobacter freundii clinical isolate.
Topics: Amino Acid Sequence; Base Sequence; beta-Lactam Resistance; beta-Lactamases; Citrobacter freundii; Conjugation, Genetic; DNA Primers; DNA, Bacterial; Enterobacteriaceae Infections; Escherichia coli K12; Genes, Bacterial; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Phylogeny; Plasmids; Recombinant Proteins; Sequence Homology, Amino Acid | 2008 |
Naturally occurring Class A ss-lactamases from the Burkholderia cepacia complex.
Topics: Alleles; Amino Acid Sequence; Amino Acid Substitution; Base Sequence; beta-Lactamases; Burkholderia cepacia complex; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Humans; Hydrolysis; Isoelectric Point; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Phylogeny; Plasmids; Sequence Analysis, DNA; Sequence Homology, Amino Acid | 2009 |
CMY-31 and CMY-36 cephalosporinases encoded by ColE1-like plasmids.
Topics: Alleles; Amino Acid Sequence; Amino Acid Substitution; Arginine; Base Sequence; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporinase; Citrobacter freundii; Cysteine; DNA Transposable Elements; DNA, Bacterial; Escherichia coli; Genes, Bacterial; Glutamine; Humans; Hydrolysis; Inhibitory Concentration 50; Isoelectric Point; Kinetics; Klebsiella pneumoniae; Microbial Sensitivity Tests; Models, Genetic; Models, Molecular; Molecular Sequence Data; Plasmids; Salmonella enterica; Sequence Analysis, DNA; Species Specificity; Substrate Specificity; Transformation, Genetic | 2009 |
Binding of faropenem and other beta-lactam agents to penicillin-binding proteins of pneumococci with various beta-lactam susceptibilities.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactams; Humans; Microbial Sensitivity Tests; Penicillin Resistance; Penicillin-Binding Proteins; Streptococcus pneumoniae | 2009 |
Extended-spectrum cephalosporinases in Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Ceftazidime; Cephalosporinase; Humans; Imipenem; Microbial Sensitivity Tests; Molecular Sequence Data; Pseudomonas aeruginosa; Sequence Analysis, DNA | 2009 |
Novel plasmid-encoded ceftazidime-hydrolyzing CTX-M-53 extended-spectrum beta-lactamase from Salmonella enterica serotypes Westhampton and Senftenberg.
Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Cardiidae; Ceftazidime; Ceftriaxone; Cephalosporin Resistance; Electrophoresis, Gel, Pulsed-Field; France; Microbial Sensitivity Tests; Plasmids; Polymerase Chain Reaction; Salmonella enterica; Serotyping | 2009 |
Comparative antipneumococcal activities of sulopenem and other drugs.
Topics: Anti-Bacterial Agents; beta-Lactam Resistance; Lactams; Microbial Sensitivity Tests; Penicillin-Binding Proteins; Streptococcus pneumoniae | 2009 |
Extended-spectrum properties of CMY-30, a Val211Gly mutant of CMY-2 cephalosporinase.
Topics: Aztreonam; beta-Lactamases; beta-Lactams; Ceftazidime; Cephalosporins; Escherichia coli Proteins; Protein Binding; Protein Structure, Secondary | 2009 |
Beta-lactamase-mediated beta-lactam resistance in Campylobacter species: prevalence of Cj0299 (bla OXA-61) and evidence for a novel beta-Lactamase in C. jejuni.
Topics: Amino Acid Sequence; Amoxicillin; Ampicillin; Animals; Anti-Bacterial Agents; Base Sequence; beta-Lactam Resistance; beta-Lactamases; Blotting, Southern; Campylobacter jejuni; Carbenicillin; Cephalosporins; Chickens; Cloxacillin; Isoelectric Focusing; Mass Spectrometry; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillins; Piperacillin; Polymerase Chain Reaction; Sequence Alignment; Ticarcillin | 2009 |
Besifloxacin, a novel fluoroquinolone, has broad-spectrum in vitro activity against aerobic and anaerobic bacteria.
Topics: Anti-Bacterial Agents; Azepines; Bacteria, Anaerobic; Drug Resistance, Bacterial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests | 2009 |
New variant of CTX-M-type extended-spectrum beta-lactamases, CTX-M-71, with a Gly238Cys substitution in a Klebsiella pneumoniae isolate from Bulgaria.
Topics: Anti-Bacterial Agents; beta-Lactamases; Bulgaria; Cefepime; Cefotaxime; Ceftazidime; Cephalosporins; Kinetics; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Sequence Data | 2009 |
IND-6, a highly divergent IND-type metallo-beta-lactamase from Chryseobacterium indologenes strain 597 isolated in Burkina Faso.
Topics: Adult; Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Ceftazidime; Cephalexin; Cephalosporins; Cephalothin; Chryseobacterium; Female; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Phylogeny; Protein Structure, Secondary; Sequence Homology, Amino Acid | 2009 |
Discovery of new inhibitors of resistant Streptococcus pneumoniae penicillin binding protein (PBP) 2x by structure-based virtual screening.
Topics: Computational Biology; Computer Simulation; Drug Discovery; Drug Evaluation, Preclinical; Drug Resistance, Bacterial; Ligands; Penicillin-Binding Proteins; Protein Binding; Streptococcus pneumoniae; Structure-Activity Relationship | 2009 |
Characterization of a new metallo-beta-lactamase gene, bla(NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Carboxylic Ester Hydrolases; Cefotaxime; Cefuroxime; Cephalosporins; Cephalothin; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; India; Kinetics; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillins; Sequence Analysis, DNA; Sequence Homology, Amino Acid | 2009 |
OXA-143, a novel carbapenem-hydrolyzing class D beta-lactamase in Acinetobacter baumannii.
Topics: Acinetobacter baumannii; Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Drug Resistance, Multiple, Bacterial; Escherichia coli; Imipenem; Meropenem; Molecular Sequence Data; Oxacillin; Penicillins; Polymerase Chain Reaction; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Thienamycins | 2009 |
A single mutation in enzyme I of the sugar phosphotransferase system confers penicillin tolerance to Streptococcus gordonii.
Topics: Amino Acid Substitution; Anti-Bacterial Agents; Carbohydrate Metabolism; Chromosome Mapping; Cloning, Molecular; Dimerization; DNA, Bacterial; Endocarditis; Energy Metabolism; Gene Deletion; Genetic Linkage; Glucose; Microbial Sensitivity Tests; Models, Molecular; Penicillin Resistance; Penicillins; Phosphoenolpyruvate Sugar Phosphotransferase System; Point Mutation; Protein Conformation; Streptococcus gordonii; Transformation, Genetic | 2010 |
Molecular and biochemical characterization of the natural chromosome-encoded class A beta-lactamase from Pseudomonas luteola.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Catheters, Indwelling; Chromosomes, Bacterial; Cloning, Molecular; Electrophoresis, Gel, Pulsed-Field; Genes, Bacterial; Genetic Variation; Isoelectric Focusing; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Phylogeny; Plasmids; Pseudomonas; Pseudomonas Infections; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Substrate Specificity | 2010 |
BEL-2, an extended-spectrum beta-lactamase with increased activity toward expanded-spectrum cephalosporins in Pseudomonas aeruginosa.
Topics: Belgium; beta-Lactamases; Cephalosporinase; Cephalosporins; Cross Infection; Escherichia coli; Genes, Bacterial; Humans; Kinetics; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections | 2010 |
Hydrolysis and inhibition profiles of beta-lactamases from molecular classes A to D with doripenem, imipenem, and meropenem.
Topics: Anti-Bacterial Agents; Bacteria; beta-Lactamase Inhibitors; Carbapenems; Doripenem; Enzyme Inhibitors; Hydrolysis; Imipenem; Kinetics; Meropenem; Microbial Sensitivity Tests; Thienamycins | 2010 |
Novel ambler class A carbapenem-hydrolyzing beta-lactamase from a Pseudomonas fluorescens isolate from the Seine River, Paris, France.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Blotting, Southern; Cloning, Molecular; DNA, Bacterial; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; France; Fresh Water; Gram-Negative Bacteria; Health Surveys; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Pseudomonas fluorescens; Water Microbiology | 2010 |
Novel VIM metallo-beta-lactamase variant from clinical isolates of Enterobacteriaceae from Algeria.
Topics: Algeria; Anti-Bacterial Agents; Base Sequence; beta-Lactamases; beta-Lactams; Carbapenems; DNA, Bacterial; Drug Resistance, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Genome, Bacterial; Hospitals, Military; Imipenem; Isoelectric Focusing; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillins; Phenotype | 2010 |
VIM-19, a metallo-beta-lactamase with increased carbapenemase activity from Escherichia coli and Klebsiella pneumoniae.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Cloning, Molecular; DNA, Bacterial; Escherichia coli; Isoelectric Focusing; Kinetics; Klebsiella pneumoniae; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Protein Conformation; Reverse Transcriptase Polymerase Chain Reaction | 2010 |
GES-13, a beta-lactamase variant possessing Lys-104 and Asn-170 in Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Aztreonam; beta-Lactamases; beta-Lactams; Cephalosporins; Genetic Variation; Humans; Integrons; Microbial Sensitivity Tests; Molecular Sequence Data; Pseudomonas aeruginosa; Pseudomonas Infections; Sequence Analysis, DNA | 2010 |
Haemophilus influenzae clinical isolates with plasmid pB1000 bearing blaROB-1: fitness cost and interspecies dissemination.
Topics: Animals; beta-Lactamases; Cefaclor; Conjugation, Genetic; Drug Resistance, Bacterial; Haemophilus Infections; Haemophilus influenzae; Humans; Molecular Epidemiology; Molecular Sequence Data; Pasteurella multocida; Plasmids; Replicon; Spain; Species Specificity; Transformation, Genetic | 2010 |
Genetic and biochemical characterization of TRU-1, the endogenous class C beta-lactamase from Aeromonas enteropelogenes.
Topics: Aeromonas; Amino Acid Sequence; Base Sequence; beta-Lactamases; Cloning, Molecular; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Genes, Bacterial; Humans; Kinetics; Molecular Sequence Data; Phylogeny; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Transformation, Genetic | 2010 |
PER-6, an extended-spectrum beta-lactamase from Aeromonas allosaccharophila.
Topics: Aeromonas; Animals; Base Sequence; beta-Lactamases; DNA Primers; DNA, Bacterial; Genes, Bacterial; Humans; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Paris; Water Microbiology | 2010 |
Activity of ceftaroline against recent emerging serotypes of Streptococcus pneumoniae in the United States.
Topics: Anti-Bacterial Agents; Ceftaroline; Cephalosporins; Communicable Diseases, Emerging; Drug Resistance, Multiple, Bacterial; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Pneumococcal Infections; Serotyping; Streptococcus pneumoniae; United States | 2010 |
Characterization of DIM-1, an integron-encoded metallo-beta-lactamase from a Pseudomonas stutzeri clinical isolate in the Netherlands.
Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; beta-Lactamases; Cloning, Molecular; DNA, Bacterial; Drug Resistance, Bacterial; Genes, Bacterial; Humans; Integrons; Middle Aged; Molecular Sequence Data; Netherlands; Pseudomonas Infections; Pseudomonas stutzeri; Sequence Homology, Amino Acid; Substrate Specificity | 2010 |
Contribution of BlaA and BlaB beta-lactamases to antibiotic susceptibility of Yersinia enterocolitica biovar 1B.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Microbial Sensitivity Tests; Polymerase Chain Reaction; Yersinia enterocolitica | 2010 |
Extended-spectrum cephalosporinase in Acinetobacter baumannii.
Topics: Acinetobacter baumannii; Amino Acid Sequence; Amino Acid Substitution; Anti-Bacterial Agents; Aztreonam; Bacterial Proteins; beta-Lactamases; Cefepime; Ceftazidime; Cephalosporin Resistance; Cephalosporinase; Cephalosporins; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Monobactams; Mutagenesis, Site-Directed | 2010 |
The ABC transporter AnrAB contributes to the innate resistance of Listeria monocytogenes to nisin, bacitracin, and various beta-lactam antibiotics.
Topics: Anti-Bacterial Agents; ATP-Binding Cassette Transporters; Bacitracin; Bacterial Proteins; beta-Lactam Resistance; Listeria monocytogenes; Nisin | 2010 |
Comparative biochemical and computational study of the role of naturally occurring mutations at Ambler positions 104 and 170 in GES β-lactamases.
Topics: Ampicillin; beta-Lactamases; Computational Biology; Escherichia coli; Hydrogen Bonding; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Protein Structure, Secondary; Ticarcillin | 2010 |
Genetic context and biochemical characterization of the IMP-18 metallo-beta-lactamase identified in a Pseudomonas aeruginosa isolate from the United States.
Topics: Amino Acid Sequence; Bacterial Proteins; beta-Lactamases; beta-Lactams; Ertapenem; Meropenem; Microbial Sensitivity Tests; Models, Genetic; Molecular Sequence Data; Open Reading Frames; Pseudomonas aeruginosa; Sequence Homology, Amino Acid; Thienamycins; United States | 2011 |
Roles of residues Cys69, Asn104, Phe160, Gly232, Ser237, and Asp240 in extended-spectrum beta-lactamase Toho-1.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Binding Sites; Cefotaxime; Escherichia coli; Microbial Sensitivity Tests; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Sequence Homology, Amino Acid; Structure-Activity Relationship; Substrate Specificity | 2011 |
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
Topics: Antitubercular Agents; Carbohydrates; Drug Resistance, Bacterial; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Oxidoreductases; Thiocarbamates; Thioglucosides | 2011 |
A new DNA gyrase inhibitor subclass of the cyclothialidine family based on a bicyclic dilactam-lactone scaffold. Synthesis and antibacterial properties.
Topics: Animals; Anti-Bacterial Agents; Bacteria; DNA Gyrase; Enzyme Inhibitors; Lactams; Lactones; Mice; Microbial Sensitivity Tests; Models, Molecular; Peptides, Cyclic; Protein Conformation; Topoisomerase II Inhibitors | 2011 |
Computational analysis of structure-based interactions and ligand properties can predict efflux effects on antibiotics.
Topics: Anti-Bacterial Agents; beta-Lactams; Computational Biology; Drug Resistance, Bacterial; Hydrophobic and Hydrophilic Interactions; Ligands; Membrane Transport Proteins; Microbial Sensitivity Tests; Models, Molecular; Protein Binding; Protein Conformation; Quantitative Structure-Activity Relationship; Regression Analysis; Thermodynamics | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Mahorones, highly brominated cyclopentenones from the red alga Asparagopsis taxiformis.
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Antifungal Agents; Cyclopentanes; Humans; Hydrocarbons, Brominated; Indian Ocean; Molecular Structure; Rhodophyta | 2014 |
Screening and Design of Inhibitor Scaffolds for the Antibiotic Resistance Oxacillinase-48 (OXA-48) through Surface Plasmon Resonance Screening.
Topics: beta-Lactamase Inhibitors; beta-Lactamases; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Humans; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Surface Plasmon Resonance | 2016 |
Novel Broad-Spectrum Antimicrobial Peptide Derived from Anoplin and Its Activity on Bacterial Pneumonia in Mice.
Topics: Animals; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Antineoplastic Agents; Cell Line; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Molecular Structure; Pneumonia, Bacterial; Pore Forming Cytotoxic Proteins; Structure-Activity Relationship; Wasp Venoms | 2021 |
[Bacteriostatic activity and killing curves of eight antibiotics against seven strains of penicillin G-resistant pneumococci].
Topics: Amoxicillin; Cefotaxime; Drug Synergism; Drug Therapy, Combination; Erythromycin; Fosfomycin; Humans; Imipenem; In Vitro Techniques; Penicillin G; Penicillin Resistance; Rifampin; Streptococcus pneumoniae; Vancomycin | 1992 |
Considerations in comparing intravenous and intramuscular antibiotics.
Topics: Anti-Bacterial Agents; Cefazolin; Cost Control; Costs and Cost Analysis; Gentamicins; Humans; Imipenem; Injections, Intramuscular; Injections, Intravenous; Penicillin G; Self Administration | 1991 |
Alteration of PBP 3 entails resistance to imipenem in Listeria monocytogenes.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Carrier Proteins; Cefotaxime; Cephalothin; Drug Resistance, Microbial; Electrophoresis; Hexosyltransferases; Imipenem; Listeria monocytogenes; Membrane Proteins; Microbial Sensitivity Tests; Muramoylpentapeptide Carboxypeptidase; Mutation; Penicillin G; Penicillin-Binding Proteins; Peptidyl Transferases | 1990 |
Transport of imipenem, a novel carbapenem antibiotic, in the rat central nervous system.
Topics: Animals; Biological Transport; Blood-Brain Barrier; Central Nervous System; Cilastatin; Imipenem; Injections, Intraventricular; Mannitol; Penicillin G; Rats | 1989 |
Role of autolysins in the activities of imipenem and CGP 31608, a novel penem, against slowly growing bacteria.
Topics: Anti-Bacterial Agents; Autolysis; Bacteria; Endopeptidases; Escherichia coli; Imipenem; Lactams; Microbial Sensitivity Tests; N-Acetylmuramoyl-L-alanine Amidase; Penicillin G; Peptidoglycan | 1989 |
Clostridium perfringens type A. Comparison of in vitro and in vivo activity of twelve antimicrobial drugs.
Topics: Animals; Anti-Bacterial Agents; Cephalosporins; Clostridium perfringens; Fosfomycin; Gas Gangrene; Imipenem; Metronidazole; Mice; Microbial Sensitivity Tests; Oxacillin; Penicillin G; Thienamycins; Vancomycin | 1986 |
Chemotherapy of experimental (murine) Clostridium perfringens type A gas gangrene.
Topics: Animals; Ciprofloxacin; Clindamycin; Clostridium perfringens; Disease Models, Animal; Gas Gangrene; Imipenem; Mice; Microbial Sensitivity Tests; Penicillin G; Rifampin | 1988 |
Comparative neurotoxicity of benzylpenicillin, imipenem/cilastatin and FCE 22101, a new injectible penem.
Topics: Animals; Anti-Bacterial Agents; Brain; Carbapenems; Cilastatin; Drug Interactions; Electroencephalography; Imipenem; Penicillin G; Rabbits | 1988 |
Neurotoxicity of beta-lactam antibiotics. Experimental kinetic and neurophysiological studies.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Blood-Brain Barrier; Brain; Carbapenems; Cilastatin; Drug Interactions; Electroencephalography; Enterobacteriaceae Infections; Female; Hippocampus; Imipenem; Male; Meningitis; Penicillin G; Rabbits; Rats; Rats, Inbred Strains; Seizures; Thiopental; Tissue Distribution; Uremia | 1988 |
The affinity of imipenem (N-formimidoylthienamycin) for the penicillin-binding proteins of Staphylococcus aureus--binding and release.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Carbon Radioisotopes; Carboxypeptidases; Carrier Proteins; Hexosyltransferases; Hot Temperature; Imipenem; Muramoylpentapeptide Carboxypeptidase; Penicillin G; Penicillin-Binding Proteins; Peptidyl Transferases; Staphylococcus aureus; Thienamycins | 1984 |
Synergy of imipenem or penicillin G and aminoglycosides against enterococci isolated from patients with infective endocarditis.
Topics: Aminoglycosides; Anti-Bacterial Agents; Drug Synergism; Drug Therapy, Combination; Endocarditis, Bacterial; Gentamicins; Humans; Imipenem; Microbial Sensitivity Tests; Penicillin G; Penicillin Resistance; Streptococcus; Streptomycin; Thienamycins | 1984 |
Susceptibility of Neisseria meningitidis and Neisseria gonorrhoeae isolates to N-formimidoyl thienamycin.
Topics: Anti-Bacterial Agents; Imipenem; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Neisseria meningitidis; Penicillin G; Thienamycins | 1982 |
Antibiotic release from impregnated pellets and beads.
Topics: Amoxicillin; Anti-Bacterial Agents; Biological Assay; Calcium Sulfate; Ciprofloxacin; Drug Carriers; Floxacillin; Gentamicins; Imipenem; In Vitro Techniques; Methylmethacrylates; Penicillin G | 1994 |
Distribution of biotypes and antimicrobial susceptibility of Actinobacillus actinomycetemcomitans.
Topics: Adolescent; Adult; Aggregatibacter actinomycetemcomitans; Anti-Bacterial Agents; Antitrichomonal Agents; Bacterial Typing Techniques; Cefoxitin; Cephamycins; Clindamycin; Dental Plaque; Drug Resistance, Microbial; Erythromycin; Female; Humans; Imipenem; Lincomycin; Male; Metronidazole; Microbial Sensitivity Tests; Penicillin G; Penicillins; Periodontitis; Tetracycline; Thienamycins | 1995 |
Dual mechanisms of GABAA response inhibition by beta-lactam antibiotics in the pyramidal neurones of the rat cerebral cortex.
Topics: Animals; Anti-Bacterial Agents; Aztreonam; Cefotiam; Chloride Channels; GABA-A Receptor Antagonists; Imipenem; In Vitro Techniques; Patch-Clamp Techniques; Penicillin G; Penicillins; Pyramidal Cells; Rats; Rats, Wistar | 1995 |
Noncompromised penicillin-resistant pneumococcal pneumonia CBA/J mouse model and comparative efficacies of antibiotics in this model.
Topics: Animals; Anti-Bacterial Agents; Cefotaxime; Disease Models, Animal; Imipenem; Lung; Male; Mice; Mice, Inbred CBA; Mice, Inbred ICR; Microbial Sensitivity Tests; Penicillin G; Penicillin Resistance; Pneumonia, Pneumococcal; Species Specificity; Streptococcus pneumoniae; Vancomycin | 1996 |
Direct application of Etest to gram-positive cocci from blood cultures: quick and reliable minimum inhibitory concentration data.
Topics: Anti-Bacterial Agents; Blood; Cefotaxime; Cephalosporins; Culture Media; Erythromycin; Gentamicins; Gram-Positive Cocci; Imipenem; Microbial Sensitivity Tests; Penicillin G; Penicillins; Thienamycins; Vancomycin | 1996 |
[Native valve infective endocarditis caused by Streptococcus bovis. Efficacy of short-term antibiotic therapy and usefulness of serial echocardiographic evaluation].
Topics: Anti-Bacterial Agents; Drug Therapy, Combination; Echocardiography; Endocarditis, Bacterial; Humans; Imipenem; Male; Middle Aged; Mitral Valve Insufficiency; Penicillin G; Penicillins; Streptococcal Infections; Streptococcus bovis; Streptomycin; Thienamycins; Time Factors | 1997 |
Soluble penicillin-binding protein 2a: beta-lactam binding and inhibition by non-beta-lactams using a 96-well format.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Binding Sites; Binding, Competitive; Biotechnology; Carbapenems; Carrier Proteins; Chemical Precipitation; Dimethyl Sulfoxide; Enzyme Inhibitors; Hexosyltransferases; Imidazoles; Imipenem; Kinetics; Methods; Micropore Filters; Muramoylpentapeptide Carboxypeptidase; Penicillin G; Penicillin-Binding Proteins; Peptidyl Transferases; Recombinant Proteins; Sensitivity and Specificity; Solubility; Triazines; Tritium | 1998 |
[Pneumococcal infections: penicillin resistance and therapeutic implications].
Topics: Amoxicillin; Ampicillin Resistance; Anti-Bacterial Agents; beta-Lactam Resistance; Cefotaxime; Cephalosporin Resistance; Cephalosporins; Drug Resistance, Microbial; Erythromycin; Humans; Imipenem; Patient Care Planning; Penicillin G; Penicillin Resistance; Penicillins; Pleural Effusion; Pneumococcal Infections; Respiratory Tract Infections; Streptococcus pneumoniae; Tetracycline Resistance; Thienamycins; Tracheal Diseases | 1995 |
Penicillin-binding protein 5 sequence alterations in clinical isolates of Enterococcus faecium with different levels of beta-lactam resistance.
Topics: Amino Acid Sequence; Amino Acid Substitution; Ampicillin; Bacterial Proteins; beta-Lactam Resistance; Carrier Proteins; Drug Resistance, Microbial; Enterococcus faecium; Genetic Variation; Gram-Positive Bacterial Infections; Hexosyltransferases; Humans; Imipenem; Microbial Sensitivity Tests; Molecular Sequence Data; Muramoylpentapeptide Carboxypeptidase; Penicillin G; Penicillin Resistance; Penicillin-Binding Proteins; Peptidyl Transferases; Piperacillin; Sequence Homology, Amino Acid; Vancomycin | 1998 |
[The frequency of Streptococcus pneumoniae strains and sensitivity surveillance for several antibiotics in Gifu Prefecture].
Topics: Amoxicillin; Anti-Bacterial Agents; Cefaclor; Cefdinir; Cefixime; Cefmenoxime; Cefpodoxime; Ceftizoxime; Cephalosporins; Ciprofloxacin; Clarithromycin; Clindamycin; Drug Resistance, Microbial; Fluoroquinolones; Humans; Imipenem; Japan; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Minocycline; Naphthyridines; Ofloxacin; Penicillin G; Penicillins; Streptococcus pneumoniae; Thienamycins | 2000 |
Antimicrobial susceptibilities of clinical Desulfovibrio isolates.
Topics: Anti-Bacterial Agents; Chloramphenicol; Clindamycin; Desulfovibrio; Drug Combinations; Humans; Imipenem; Metronidazole; Microbial Sensitivity Tests; Penicillin G | 2001 |
[Drug interactions between nonsteroidal anti-inflammatory drug and pazufloxacin mesilate, a new quinolone antibacterial agent for intravenous use: convulsions in mice after intravenous or intracerebroventricular administration].
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; beta-Alanine; Biphenyl Compounds; Cefazolin; Cilastatin; Cilastatin, Imipenem Drug Combination; Ciprofloxacin; Convulsants; Drug Combinations; Drug Interactions; Enoxacin; Fleroxacin; Fluoroquinolones; Imipenem; Injections, Intravenous; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Norfloxacin; Oxazines; Penicillin G; Quinolones; Seizures; Thienamycins | 2002 |
Antimicrobial susceptibility of major pathogens of orofacial odontogenic infections to 11 beta-lactam antibiotics.
Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Bacteroidaceae Infections; beta-Lactams; Cefepime; Cefmetazole; Cefoperazone; Cefpirome; Ceftazidime; Ceftizoxime; Cephalosporins; Drug Resistance, Bacterial; Drug Therapy, Combination; Fusobacterium; Fusobacterium Infections; Gram-Positive Bacterial Infections; Humans; Imipenem; Lactams; Microbial Sensitivity Tests; Mouth Diseases; Penicillin G; Penicillins; Peptostreptococcus; Porphyromonas gingivalis; Prevotella; Streptococcal Infections; Streptococcus; Sulbactam | 2002 |
Structural determinants of substrate binding to Bacillus cereus metallo-beta-lactamase.
Topics: Anti-Bacterial Agents; Bacillus cereus; beta-Lactamases; Cefotaxime; Cephapirin; Dose-Response Relationship, Drug; Hydrolysis; Imipenem; Ions; Kinetics; Models, Chemical; Penicillin G; Protein Binding; Protein Conformation; Substrate Specificity; Temperature; Time Factors; Zinc | 2004 |
Molecular analysis of antimicrobial agent translocation through the membrane porin BpsOmp38 from an ultraresistant Burkholderia pseudomallei strain.
Topics: Amino Acid Sequence; Anti-Infective Agents; Bacterial Outer Membrane Proteins; beta-Lactams; Biological Transport; Burkholderia pseudomallei; Cefepime; Ceftazidime; Cephalosporins; Ertapenem; Humans; Imipenem; Kinetics; Lipid Bilayers; Melioidosis; Meropenem; Models, Molecular; Molecular Sequence Data; Norfloxacin; Penicillin G; Phospholipids; Porins; Protein Conformation; Sequence Homology, Amino Acid; Thienamycins | 2011 |
Biochemical and structural characterization of the subclass B1 metallo-β-lactamase VIM-4.
Topics: Ampicillin; Anti-Bacterial Agents; beta-Lactamases; Cephalosporins; Cephalothin; Crystallography, X-Ray; Escherichia coli; Imipenem; Magnetic Resonance Spectroscopy; Meropenem; Penicillin G; Thienamycins | 2011 |
The role of the β5-α11 loop in the active-site dynamics of acylated penicillin-binding protein A from Mycobacterium tuberculosis.
Topics: Acylation; Apoenzymes; Binding Sites; Catalytic Domain; Ceftriaxone; Crystallography, X-Ray; Imipenem; Kinetics; Models, Molecular; Mycobacterium tuberculosis; Penicillin G; Penicillin-Binding Proteins; Protein Conformation; Staphylococcal Protein A | 2012 |
Inhibition of a cold-active alkaline phosphatase by imipenem revealed by in silico modeling of metallo-β-lactamase active sites.
Topics: Aeromonas hydrophila; Alkaline Phosphatase; Amino Acid Motifs; Animals; beta-Lactamases; Catalytic Domain; Cold Temperature; Computational Biology; Enzyme Inhibitors; Hydrolysis; Imipenem; Models, Molecular; Penicillin G; Static Electricity | 2012 |
Antibiotic resistance pattern of Bacteroides fragilis isolated from clinical and colorectal specimens.
Topics: Anti-Bacterial Agents; Bacterial Toxins; Bacteroides fragilis; Bacteroides Infections; Cefoxitin; Clindamycin; Cross-Sectional Studies; DNA, Bacterial; Drug Resistance, Bacterial; Gastrointestinal Tract; Genes, Bacterial; Humans; Imipenem; Inpatients; Metalloendopeptidases; Metronidazole; Microbial Sensitivity Tests; Penicillin G; Polymerase Chain Reaction; RNA, Ribosomal, 16S; Tetracycline | 2021 |