Page last updated: 2024-08-17

penicillin g and ceftriaxone

penicillin g has been researched along with ceftriaxone in 53 studies

Research

Studies (53)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (3.77)	18.2507
2000's	30 (56.60)	29.6817
2010's	19 (35.85)	24.3611
2020's	2 (3.77)	2.80

Authors

Authors	Studies
Balsamo, A; Barontini, S; Calvani, F; Di Modugno, E; Felici, A; Gentili, D; Macchia, M; Rossello, A	1
Apiwattanakul, N; Endou, H; Jariyawat, S; Kanai, Y; Sekine, T; Sophasan, S; Takeda, M	1
Brandsch, M; Luckner, P	1
Biegel, A; Brandsch, M; Gebauer, S; Hartrodt, B; Neubert, K; Thondorf, I	1
Aubert, D; Naas, T; Nordmann, P; Ozcan, A	1
Fredlund, H; Lindberg, R; Nicholas, R; Unemo, M	1
Kwon, DH; Lu, CD	1
Miriagou, V; Papagiannitsis, CC; Tzelepi, E; Tzouvelekis, LS	1
Girlich, D; Leclercq, R; Naas, T; Nordmann, P	1
Fiett, J; Gniadkowski, M; Hakenbeck, R; Hryniewicz, W; Izdebski, R; Rutschmann, J; Sadowy, E	1
Bonnet, R; Caniça, M; Ferreira, E; Manageiro, V; Mendonça, N; Robin, F; Salgado, MJ	1
Beckius, ML; Fraser, SL; Galloway, RL; Griffith, ME; Hospenthal, DR; Mende, K; Miller, RS; Murray, CK; Pimentel, G; Ressner, RA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Benton, BM; Debabov, DV; Difuntorum, S; Krause, KM; Renelli, M; Wu, TX	1
Docquier, JD; Frère, JM; Rossolini, GM; Stoczko, M	1
Amsler, KM; Bush, K; Davies, TA; Jacobs, MR; Shang, W	1
Biek, D; Ge, Y; Sahm, DF; Talbot, GH	1
Arpin, C; Bezian, MC; Coulange, L; Demarthe, F; Dubois, V; Minarini, LA; Nordmann, P; Poirel, L; Quentin, C	1
Aguilar, L; Biek, D; Fenoll, A; Giménez, MJ; Granizo, JJ; Robledo, O; Tarragó, D	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Beall, B; Biek, D; du Plessis, M; Ge, Y; Klugman, KP; Klugman, M; McGee, L; Smith, AM; Whitney, CG	1
Kotsakis, SD; Miriagou, V; Tzelepi, E; Tzouvelekis, LS; Whichard, JM; Zioga, A	1
Bell, JM; Biedenbach, DJ; Jones, RN; Sader, HS; Turnidge, JD	1
Caugant, DA; Fredlund, H; Hedberg, ST; Nicolas, P; Olcén, P; Unemo, M	1
Bonnet, R; Brisabois, A; Cloeckaert, A; Doublet, B; Fabre, L; Granier, SA; Robin, F; Weill, FX	1
Appelbaum, PC; Ednie, LM; Kosowska-Shick, K; McGhee, P	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Hafkin, B; Hoban, DJ; Kaplan, N; Karlowsky, JA; Zhanel, GG	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
De Luca, F; Delmarcelle, M; Docquier, JD; Dubus, A; Frère, JM; Nacoulma, OG; Rossolini, GM; Simporé, J; Zeba, B	1
Arhin, FF; Draghi, DC; Moeck, G; Parr, TR; Pillar, CM; Sahm, DF	1
Distèche-Nguyen, M; Gerards, T; Luxen, A; Miguet, L; Pasha, FA; Thomas, A; Zervosen, A	1
Barthold, SW; Feng, S; Hodzic, E; Imai, DM; Luft, BJ; Yang, X	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
Kotsakis, SD; Legakis, NJ; Miriagou, V; Papagiannitsis, CC; Tzelepi, E; Tzouvelekis, LS	1
De Luca, F; Docquier, JD; Fosse, T; Giraud-Morin, C; Rossolini, GM	1
Appelbaum, PC; Kosowska-Shick, K; McGhee, PL	1
Bajaksouzian, S; Biek, D; Critchley, IA; Good, CE; Jacobs, MR; Jones, RN; Sader, HS; Windau, AR	1
Ohnishi, M; Okamura, N; Ono, E; Shimuta, K; Watanabe, H	1
Bent, ZW; Young, GM	1
Biedenbach, DJ; Castanheira, M; Jones, RN	1
Biedenbach, DJ; Hammerschlag, MR; Jones, RN; Kohlhoff, SA; Roblin, PM	1
Bush, K; Davies, TA; Flamm, RK; He, W	1
Huang, CT; Li, LH; Li, SY; Liao, MH; Lin, KY; Wong, WW; Yen, MY	1
Borgianni, L; Docquier, JD; Hanson, ND; Prandi, S; Rossolini, GM; Salden, L; Santella, G	1
Allen, VG; Farrell, DJ; Lo, S; Low, DE; Melano, RG; Perusini, SJ; Rebbapragada, A; Tan, J; Tijet, N; Towns, L	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Anderson, KC; Kellogg, GE; Sarkar, A	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Gao, F; Huang, G; Xiao, J	1
Amada, H; Endo, M; Hitaka, K; Kamitani, M; Masuko, A; Mihara, Y; Mima, M; Ohtake, N; Sugiyama, H; Takata, I; Takeuchi, T; Tamura, Y; Tanaka-Yamamoto, N; Ushiyama, F; Wada, R	1
Bhando, T; Brown, ED; Carfrae, L; Ellis, MJ; Johnson, JW; MacNair, C; Magolan, J; Piquette, ZA; Ritchie, NE; Saliba, P	1

Reviews

2 review(s) available for penicillin g and ceftriaxone

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Current scenario of tetrazole hybrids for antibacterial activity. European journal of medicinal chemistry, 2019, Dec-15, Volume: 184 Topics: Anti-Bacterial Agents; Bacteria; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Tetrazoles	2019

Trials

1 trial(s) available for penicillin g and ceftriaxone

Article	Year
In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:9 Topics: Anti-Bacterial Agents; Cephalosporins; Enterobacteriaceae; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Skin Diseases, Bacterial; Staphylococcus	2008

Article

Year

In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections.

Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:9

Topics: Anti-Bacterial Agents; Cephalosporins; Enterobacteriaceae; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Skin Diseases, Bacterial; Staphylococcus

2008

Other Studies

50 other study(ies) available for penicillin g and ceftriaxone

Article	Year
New N-substituted 7-aminocephalosporanic acid derivatives as potential agents against Streptococcus pneumoniae. Synthesis and in vitro activity. Bioorganic & medicinal chemistry letters, 1999, Apr-05, Volume: 9, Issue:7 Topics: Anti-Bacterial Agents; Cephalosporins; Microbial Sensitivity Tests; Staphylococcus aureus; Streptococcus pneumoniae; Streptococcus pyogenes; Structure-Activity Relationship	1999
The interaction and transport of beta-lactam antibiotics with the cloned rat renal organic anion transporter 1. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:2 Topics: Animals; Anion Transport Proteins; Anti-Bacterial Agents; Biological Transport; Carrier Proteins; Cell Survival; Cephaloridine; Cephalosporins; In Vitro Techniques; Kidney; Kinetics; Oocytes; p-Aminohippuric Acid; Penicillin G; Rats; Recombinant Proteins; Xenopus laevis	1999
Interaction of 31 beta-lactam antibiotics with the H+/peptide symporter PEPT2: analysis of affinity constants and comparison with PEPT1. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2005, Volume: 59, Issue:1 Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Binding Sites; Caco-2 Cells; Dose-Response Relationship, Drug; Humans; Peptide Transporter 1; Protein Binding; Rats; Symporters	2005
Three-dimensional quantitative structure-activity relationship analyses of beta-lactam antibiotics and tripeptides as substrates of the mammalian H+/peptide cotransporter PEPT1. Journal of medicinal chemistry, 2005, Jun-30, Volume: 48, Issue:13 Topics: Animals; beta-Lactams; Cell Line, Tumor; Dipeptides; Drug Design; Humans; Mammals; Models, Molecular; Oligopeptides; Peptide Transporter 1; Quantitative Structure-Activity Relationship; Substrate Specificity; Symporters	2005
Chromosome-encoded narrow-spectrum Ambler class A beta-lactamase GIL-1 from Citrobacter gillenii. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4 Topics: beta-Lactamases; Chromosomes; Chromosomes, Bacterial; Citrobacter; Cloning, Molecular; DNA, Bacterial; Escherichia coli; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Genes, Bacterial; Molecular Sequence Data	2007
Neisseria gonorrhoeae isolates with reduced susceptibility to cefixime and ceftriaxone: association with genetic polymorphisms in penA, mtrR, porB1b, and ponA. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6 Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Cefixime; Ceftriaxone; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Neisseria gonorrhoeae; Penicillin-Binding Proteins; Polymorphism, Genetic; Porins; Repressor Proteins	2007
Polyamine effects on antibiotic susceptibility in bacteria. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6 Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactams; Drug Resistance, Bacterial; Drug Synergism; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Polyamines; Spermine; Staphylococcus aureus	2007
Plasmid-encoded ACC-4, an extended-spectrum cephalosporinase variant from Escherichia coli. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:10 Topics: Anti-Bacterial Agents; Cephalosporinase; Culture Media; DNA Primers; Drug Resistance, Bacterial; Escherichia coli; Kinetics; Models, Molecular; Molecular Sequence Data; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; Spectrophotometry, Ultraviolet	2007
Molecular and biochemical characterization of the chromosome-encoded class A beta-lactamase BCL-1 from Bacillus clausii. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:11 Topics: Amino Acid Sequence; Bacillus; Bacterial Proteins; beta-Lactamases; Chromosome Mapping; Chromosomes, Bacterial; Cloning, Molecular; Microbial Sensitivity Tests; Molecular Sequence Data; Molecular Weight; Sequence Homology, Amino Acid; Substrate Specificity	2007
Highly variable penicillin resistance determinants PBP 2x, PBP 2b, and PBP 1a in isolates of two Streptococcus pneumoniae clonal groups, Poland 23F-16 and Poland 6B-20. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:3 Topics: Amino Acid Sequence; Aminoacyltransferases; Anti-Bacterial Agents; Antigenic Variation; Bacterial Proteins; Boron Compounds; Clone Cells; Genetic Variation; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillin Resistance; Penicillin-Binding Proteins; Penicillins; Peptidyl Transferases; Poland; Sequence Analysis, DNA; Streptococcus pneumoniae	2008
The Lys234Arg substitution in the enzyme SHV-72 is a determinant for resistance to clavulanic acid inhibition. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:5 Topics: Amino Acid Substitution; Amoxicillin; Anti-Bacterial Agents; Arginine; Aztreonam; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Clavulanic Acid; Computer Simulation; Imipenem; Isoelectric Focusing; Kinetics; Klebsiella pneumoniae; Lysine; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; Penicillins; Protein Conformation; Protein Structure, Tertiary	2008
Antimicrobial susceptibilities of geographically diverse clinical human isolates of Leptospira. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8 Topics: Ampicillin; Anti-Bacterial Agents; Azithromycin; Cefepime; Cefotaxime; Ceftriaxone; Cephalosporins; Ciprofloxacin; Egypt; Hawaii; Humans; Leptospira; Leptospirosis; Levofloxacin; Microbial Sensitivity Tests; Nicaragua; Ofloxacin; Tetracycline; Thailand	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
In vitro activity of telavancin against resistant gram-positive bacteria. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:7 Topics: Aminoglycosides; Anti-Bacterial Agents; Drug Resistance, Bacterial; Enterococcus; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; In Vitro Techniques; Lipoglycopeptides; Methicillin Resistance; Microbial Sensitivity Tests; Staphylococcus; Streptococcus	2008
Functional diversity among metallo-beta-lactamases: characterization of the CAR-1 enzyme of Erwinia carotovora. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:7 Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; beta-Lactamases; Cloning, Molecular; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Genes, Bacterial; Molecular Sequence Data; Open Reading Frames; Pectobacterium carotovorum; Phenotype; Phylogeny; Recombinant Proteins; Sequence Homology, Amino Acid	2008
In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:9 Topics: Anti-Bacterial Agents; Ceftaroline; Cephalosporins; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; United States	2008
Molecular and biochemical characterization of SHV-56, a novel inhibitor-resistant beta-lactamase from Klebsiella pneumoniae. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:10 Topics: Aged; Amino Acid Substitution; Base Sequence; beta-Lactam Resistance; beta-Lactamases; DNA Primers; DNA, Bacterial; Female; Genes, Bacterial; Humans; Isoelectric Point; Kinetics; Klebsiella Infections; Klebsiella pneumoniae; Molecular Sequence Data; Mutagenesis, Insertional; Recombinant Proteins	2008
In vitro activity of ceftaroline against Streptococcus pneumoniae isolates exhibiting resistance to penicillin, amoxicillin, and cefotaxime. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:11 Topics: Amoxicillin; Anti-Bacterial Agents; Cefotaxime; Ceftaroline; Cephalosporin Resistance; Cephalosporins; Drug Resistance, Multiple, Bacterial; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Penicillin Resistance; Penicillins; Pneumococcal Infections; Streptococcus pneumoniae	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
In vitro evaluation of the antimicrobial activity of ceftaroline against cephalosporin-resistant isolates of Streptococcus pneumoniae. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:2 Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Typing Techniques; Ceftaroline; Cephalosporins; DNA, Bacterial; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillin-Binding Proteins; Pneumococcal Infections; Streptococcus pneumoniae	2009
CMY-31 and CMY-36 cephalosporinases encoded by ColE1-like plasmids. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:3 Topics: Alleles; Amino Acid Sequence; Amino Acid Substitution; Arginine; Base Sequence; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporinase; Citrobacter freundii; Cysteine; DNA Transposable Elements; DNA, Bacterial; Escherichia coli; Genes, Bacterial; Glutamine; Humans; Hydrolysis; Inhibitory Concentration 50; Isoelectric Point; Kinetics; Klebsiella pneumoniae; Microbial Sensitivity Tests; Models, Genetic; Models, Molecular; Molecular Sequence Data; Plasmids; Salmonella enterica; Sequence Analysis, DNA; Species Specificity; Substrate Specificity; Transformation, Genetic	2009
Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:3 Topics: Anti-Bacterial Agents; Asia; Drug Resistance, Bacterial; Europe; Gram-Positive Bacteria; Humans; Latin America; Microbial Sensitivity Tests; North America; Pacific Ocean; Quality Control; Teicoplanin; Vancomycin	2009
Antibiotic susceptibility and characteristics of Neisseria meningitidis isolates from the African meningitis belt, 2000 to 2006: phenotypic and genotypic perspectives. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:4 Topics: Africa; Genotype; Humans; Meningitis, Meningococcal; Microbial Sensitivity Tests; Neisseria meningitidis; Phenotype; Sequence Analysis, DNA; Time Factors	2009
Novel plasmid-encoded ceftazidime-hydrolyzing CTX-M-53 extended-spectrum beta-lactamase from Salmonella enterica serotypes Westhampton and Senftenberg. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:5 Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Cardiidae; Ceftazidime; Ceftriaxone; Cephalosporin Resistance; Electrophoresis, Gel, Pulsed-Field; France; Microbial Sensitivity Tests; Plasmids; Polymerase Chain Reaction; Salmonella enterica; Serotyping	2009
Comparative antipneumococcal activities of sulopenem and other drugs. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:6 Topics: Anti-Bacterial Agents; beta-Lactam Resistance; Lactams; Microbial Sensitivity Tests; Penicillin-Binding Proteins; Streptococcus pneumoniae	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:8 Topics: Anti-Bacterial Agents; Benzofurans; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Enterobacteriaceae; Enterococcus; Microbial Sensitivity Tests; Moraxella catarrhalis; Pyrones; Staphylococcal Infections; Staphylococcus; Staphylococcus aureus; Staphylococcus epidermidis; Streptococcus pneumoniae	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
IND-6, a highly divergent IND-type metallo-beta-lactamase from Chryseobacterium indologenes strain 597 isolated in Burkina Faso. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:10 Topics: Adult; Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Ceftazidime; Cephalexin; Cephalosporins; Cephalothin; Chryseobacterium; Female; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Phylogeny; Protein Structure, Secondary; Sequence Homology, Amino Acid	2009
Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:11 Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Enterococcus faecium; Glycopeptides; Gram-Positive Bacteria; Humans; Lipoglycopeptides; Microbial Sensitivity Tests; Staphylococcus aureus; Streptococcus	2009
Discovery of new inhibitors of resistant Streptococcus pneumoniae penicillin binding protein (PBP) 2x by structure-based virtual screening. Journal of medicinal chemistry, 2009, Oct-08, Volume: 52, Issue:19 Topics: Computational Biology; Computer Simulation; Drug Discovery; Drug Evaluation, Preclinical; Drug Resistance, Bacterial; Ligands; Penicillin-Binding Proteins; Protein Binding; Streptococcus pneumoniae; Structure-Activity Relationship	2009
Ineffectiveness of tigecycline against persistent Borrelia burgdorferi. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:2 Topics: Animals; Anti-Bacterial Agents; Antigens, Surface; Bacterial Outer Membrane Proteins; Bacterial Vaccines; Borrelia burgdorferi; Ceftriaxone; Female; Lipoproteins; Lyme Disease; Mice; Microbial Sensitivity Tests; Minocycline; Polymerase Chain Reaction; Ticks; Tigecycline	2010
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
GES-13, a beta-lactamase variant possessing Lys-104 and Asn-170 in Pseudomonas aeruginosa. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:3 Topics: Anti-Bacterial Agents; Aztreonam; beta-Lactamases; beta-Lactams; Cephalosporins; Genetic Variation; Humans; Integrons; Microbial Sensitivity Tests; Molecular Sequence Data; Pseudomonas aeruginosa; Pseudomonas Infections; Sequence Analysis, DNA	2010
Genetic and biochemical characterization of TRU-1, the endogenous class C beta-lactamase from Aeromonas enteropelogenes. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:4 Topics: Aeromonas; Amino Acid Sequence; Base Sequence; beta-Lactamases; Cloning, Molecular; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Genes, Bacterial; Humans; Kinetics; Molecular Sequence Data; Phylogeny; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Transformation, Genetic	2010
Affinity of ceftaroline and other beta-lactams for penicillin-binding proteins from Staphylococcus aureus and Streptococcus pneumoniae. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:5 Topics: Anti-Bacterial Agents; beta-Lactams; Binding, Competitive; Cefotaxime; Ceftaroline; Cephalosporins; Drug Resistance, Microbial; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Penicillin G; Streptococcus pneumoniae	2010
Activity of ceftaroline against recent emerging serotypes of Streptococcus pneumoniae in the United States. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:6 Topics: Anti-Bacterial Agents; Ceftaroline; Cephalosporins; Communicable Diseases, Emerging; Drug Resistance, Multiple, Bacterial; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Pneumococcal Infections; Serotyping; Streptococcus pneumoniae; United States	2010
Identification of TEM-135 beta-lactamase in penicillinase-producing Neisseria gonorrhoeae strains in Japan. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:7 Topics: beta-Lactamases; Japan; Molecular Sequence Data; Neisseria gonorrhoeae; Penicillinase; Plasmids	2010
Contribution of BlaA and BlaB beta-lactamases to antibiotic susceptibility of Yersinia enterocolitica biovar 1B. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:9 Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Microbial Sensitivity Tests; Polymerase Chain Reaction; Yersinia enterocolitica	2010
Determination of CEM-101 activity tested against clinical isolates of Neisseria meningitidis from a worldwide collection. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:9 Topics: Anti-Bacterial Agents; Azithromycin; Ceftriaxone; Ciprofloxacin; Humans; Ketolides; Macrolides; Microbial Sensitivity Tests; Minocycline; Neisseria meningitidis; Penicillins; Rifampin; Sulfamethoxazole; Triazoles; Trimethoprim	2010
Update on fusidic acid (CEM-102) tested against Neisseria gonorrhoeae and Chlamydia trachomatis. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:10 Topics: Anti-Bacterial Agents; Chlamydia trachomatis; Fusidic Acid; Neisseria gonorrhoeae	2010
Affinity of ceftobiprole for penicillin-binding protein 2b in Streptococcus pneumoniae strains with various susceptibilities to penicillin. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:10 Topics: Anti-Bacterial Agents; Ceftriaxone; Cephalosporins; Inhibitory Concentration 50; Microbial Sensitivity Tests; Penicillin-Binding Proteins; Penicillins; Protein Binding; Streptococcus pneumoniae	2010
Characteristics and dissemination of mosaic penicillin-binding protein 2-harboring multidrug-resistant Neisseria gonorrhoeae isolates with reduced cephalosporin susceptibility in northern Taiwan. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:11 Topics: Anti-Bacterial Agents; Cephalosporins; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Humans; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Penicillin-Binding Proteins; Penicillins; Sexually Transmitted Diseases, Bacterial; Taiwan	2010
Genetic context and biochemical characterization of the IMP-18 metallo-beta-lactamase identified in a Pseudomonas aeruginosa isolate from the United States. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:1 Topics: Amino Acid Sequence; Bacterial Proteins; beta-Lactamases; beta-Lactams; Ertapenem; Meropenem; Microbial Sensitivity Tests; Models, Genetic; Molecular Sequence Data; Open Reading Frames; Pseudomonas aeruginosa; Sequence Homology, Amino Acid; Thienamycins; United States	2011
Molecular analysis of antimicrobial resistance mechanisms in Neisseria gonorrhoeae isolates from Ontario, Canada. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:2 Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Cefixime; Ceftriaxone; Cephalosporins; DNA, Bacterial; Drug Resistance, Bacterial; Gonorrhea; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Neisseria gonorrhoeae; Ontario; Penicillin-Binding Proteins; Polymerase Chain Reaction; Sequence Analysis, DNA	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Computational analysis of structure-based interactions and ligand properties can predict efflux effects on antibiotics. European journal of medicinal chemistry, 2012, Volume: 52 Topics: Anti-Bacterial Agents; beta-Lactams; Computational Biology; Drug Resistance, Bacterial; Hydrophobic and Hydrophilic Interactions; Ligands; Membrane Transport Proteins; Microbial Sensitivity Tests; Models, Molecular; Protein Binding; Protein Conformation; Quantitative Structure-Activity Relationship; Regression Analysis; Thermodynamics	2012
Lead optimization of 8-(methylamino)-2-oxo-1,2-dihydroquinolines as bacterial type II topoisomerase inhibitors. Bioorganic & medicinal chemistry, 2020, 11-15, Volume: 28, Issue:22 Topics: Anti-Bacterial Agents; Cell Survival; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Hep G2 Cells; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Quinolines; Streptococcus pneumoniae; Structure-Activity Relationship; Topoisomerase II Inhibitors; Transcriptional Regulator ERG; Vancomycin-Resistant Enterococci	2020
Antibacterial Activity of Metergoline Analogues: Revisiting the Ergot Alkaloid Scaffold for Antibiotic Discovery. ACS medicinal chemistry letters, 2022, Feb-10, Volume: 13, Issue:2 Topics:	2022