Page last updated: 2024-08-17

penicillanic acid and fr 264205

penicillanic acid has been researched along with fr 264205 in 62 studies

Research

Studies (62)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	48 (77.42)	24.3611
2020's	14 (22.58)	2.80

Authors

Authors	Studies
Bulik, CC; Christensen, H; Nicolau, DP	1
Ge, Y; Livermore, DM; Mushtaq, S	1
Farrell, DJ; Jones, RN; Rhomberg, PR; Sader, HS	1
Ge, Y; Giske, CG; Karlsson, IM; Titelman, E	1
Bulik, CC; Keel, RA; Nicolau, DP; Sutherland, CA; Tessier, PR	1
Adam, H; Baxter, M; Hoban, DJ; Karlowsky, JA; Lagacé-Wiens, P; Walkty, A; Zhanel, GG	1
Ambrose, PG; Bhavnani, SM; Bulik, CC; Forrest, A; Friedrich, LV; Jones, RN; McCauley, J; Mendes, RE; Okusanya, OO; Steenbergen, JN; Vanscoy, B	1
Jacobus, NV; McDermott, LA; Snydman, DR	1
Adam, H; Chung, P; Denisuik, A; Gin, AS; Hoban, DJ; Karlowsky, JA; Lagacé-Wiens, PR; Lynch, JP; Rubinstein, E; Schweizer, F; Walkty, A; Zelenitsky, S; Zhanel, GG	1
Jones, RN; Rhomberg, PR; Sader, HS	1
Chandorkar, G; Hershberger, E; Krishna, G; Miller, B; Wooley, M	1
Bruchmann, S; Cabot, G; Haussler, S; Juan, C; Moyà, B; Mulet, X; Oliver, A; Zamorano, L	1
Castanheira, M; Farrell, DJ; Flamm, RK; Jones, RN; Sader, HS	1
Ambrose, PG; Bhavnani, SM; Castanheira, M; Friedrich, LV; Jones, RN; McCauley, J; Mendes, RE; Steenbergen, JN; VanScoy, BD	1
Boutoille, D; Bretonnière, C; Caillon, J; Desessard, C; Guitton, C; Jacqueline, C; Potel, G	1
Aguilar, L; Gilsanz, F; Gimenez, MJ; Maseda, E	1
Chandorkar, G; Hershberger, E; Krishna, G; Mouksassi, MS; Xiao, A	1
Eckmann, C; Solomkin, J	1
Bassetti, M; Righi, E	1
Lagarde, C; Mavridou, E; Melchers, MJ; Mouton, JW; Seyedmousavi, S; van Mil, AC	1
Melchers, MJ; Mouton, JW; van Mil, AC	1
Nicolau, DP; Sutherland, CA	2
Huntington, JA; Miller, BW; Nicolau, DP; Xiao, AJ	1
Burnham, CA; Dubberke, ER; Gonzalez, MD; Hink, T; Wallace, MA	1
Bowker, KE; MacGowan, AP; Nicholls, D; Noel, AR; Tomaselli, SG	1
Cluck, D; Lewis, P; Moorman, J; Spivey, J; Stayer, B	1
Hsu, AJ; Tamma, PD; Tamma, SM	1
Gonzales, JP; Heil, EL; Mehrotra, S; Nicolau, DP; Oliver, WD; Robinett, K; Saleeb, P	1
Scott, LJ	1
Alkrouk, A; Buehrle, DJ; Chen, L; Clancy, CJ; Hao, B; Kreiswirth, BN; Nguyen, MH; Potoski, BA; Press, EG; Shields, RK	1
Arya, A; Barber, KE; Hallesy, J; Rybak, MJ; Singh, NB; Smith, JR; Yim, J	1
Alverdy, J; Hershberger, E; Miller, B; Popejoy, MW; Steenbergen, JN	1
Aitken, SL; Bhatti, MM; DePombo, AM; Gettys, SC; Kontoyiannis, DP; Nicolau, DP; Nunez, CA; Tverdek, FP	1
Algora-Weber, A; de la Calle-Pedrosa, N; Delgado-Iribarren, A; Gabán-Díez, Á; González-Jiménez, AI; Hernández-Tejedor, A; Martín-Vivas, A; Merino-Vega, CD; Ruiz de Luna-González, R; Temprano-Gómez, I	1
Goldstein, EJ; Kullar, R; Long, J; Popejoy, MW; Wagenlehner, FM; Yu, B	1
Compain, F; Grohs, P; Kaibi, I; Lavollay, M; Mainardi, JL; Morand, P; Podglajen, I; Taieb, G	1
Chaijamorn, W; Lewis, SJ; Mueller, BA; Shaw, AR	1
Abbo, LM; Adachi, J; Aitken, SL; Araos, R; Arias, CA; Bonomo, RA; Jain, R; Lichtenberger, PN; Miller, WR; Munita, JM; Nigo, M; Perez, F; Rakita, R; Rosa, R; Shelburne, S; Shimose, LA; Tran, TT; Wanger, A	1
Basu, A; Borse, RH; Gaultney, J; Kauf, TL; Medic, G; Miller, B; Prabhu, VS; Sen, SS	1
Huntington, JA; Long, J; Popejoy, MW	1
Castanheira, M; Flamm, RK; Pfaller, MA; Shortridge, D	2
Davido, B; de Truchis, P; Dinh, A; Salomon, J; Senard, O	1
Alatoom, A	1
Cheng, S; Clancy, CJ; Cooper, VS; Doi, Y; Haidar, G; Hao, B; Nguyen, MH; Philips, NJ; Potoski, BA; Press, EG; Shields, RK; Snyder, D	1
Aguilar-Aguilar, G; Alós-Almiñana, M; Belda-Nacher, JF; Carbonell, JA; Ezquer-Garin, C; Ferriols-Lisart, R	1
Finklea, JD; Hollaway, R; Jain, R; Le, J; Lee, F; Lowe, K	1
Bonomo, RA; Davis, SL; Dhar, S; File, TM; Gerlach, AT; Kaye, KS; Olson, S; Patel, TS; Perez, F; Pogue, JM; Puzniak, LA; Veve, MP	1
Dorn, C; Eberl, S; Nussbaumer-Pröll, AK; Reiter, B; Stimpfl, T; Zeitlinger, M	1
Carvalhaes, CG; Duncan, LR; Flamm, RK; Sader, HS; Shortridge, D	1
Forland, SC; Guerrero-Wooley, RL; Hino, G; Park, SH; Winans, SA	1
Murri, R; Sacco, E	1
Al Jalali, V; Dorn, C; Kratzer, A; Lackner, E; Matzneller, P; Österreicher, Z; Taubert, M; Wölfl-Duchek, M; Wulkersdorfer, B; Zeitlinger, M	1
Bremmer, DN; Kline, EG; Nicolau, DP; Shah, S; Shields, RK	1
Gillani, SW; Hussain, MW; Mahmood, RK; Rathore, HA; Saeed, MW; Vippadapu, P	1
Castanheira, M; Chen, WT; Pfaller, M; Shortridge, D; Streit, J; Tulloch, M	1
Ashouri, N; Bensaci, M; Bradley, JS; Bruno, CJ; De Anda, C; Huntington, JA; Johnson, MG; Lonchar, J; Popejoy, MW; Rhee, EG; Roilides, E; Su, FH	1
Akrich, B; DeRyke, CA; Hawser, SP; Karlowsky, JA; Lob, SH; Motyl, MR; Sahm, DF; Siddiqui, F; Young, K	1
Bensaci, M; Bruno, CJ; De Anda, C; Dementieva, N; Huntington, JA; Jackson, CA; Johnson, MG; Lonchar, J; Newland, J; Popejoy, MW; Rhee, EG; Su, FH	1
Fujimori, T; Hagiya, H; Higashikage, A; Iio, K; Kakehi, A; Minabe, H; Okura, M; Otsuka, F; Yokoyama, Y	1
Ishizawa, T; Kimura, K; Kinoshita, M; Kubo, S; Nishio, K; Ohira, G; Okada, T; Shinkawa, H; Shirai, D; Tanaka, S; Tani, N; Tauchi, J	1

Reviews

6 review(s) available for penicillanic acid and fr 264205

Article	Year
Ceftolozane/tazobactam: a novel cephalosporin/β-lactamase inhibitor combination with activity against multidrug-resistant gram-negative bacilli. Drugs, 2014, Volume: 74, Issue:1 Topics: Animals; Anti-Bacterial Agents; Cephalosporins; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Gram-Negative Bacterial Infections; Humans; Penicillanic Acid; Tazobactam	2014
Ceftolozane/tazobactam (CXA 201) for the treatment of intra-abdominal infections. Expert review of anti-infective therapy, 2014, Volume: 12, Issue:11 Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; Cephalosporins; Drug Combinations; Enzyme Inhibitors; Humans; Intraabdominal Infections; Penicillanic Acid; Tazobactam	2014
Ceftolozane/tazobactam for the treatment of complicated intra-abdominal infections. Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:2 Topics: Anti-Bacterial Agents; Cephalosporins; Clinical Trials, Phase III as Topic; Drug Combinations; Drug Resistance, Bacterial; Gram-Negative Bacterial Infections; Humans; Intraabdominal Infections; Penicillanic Acid; Tazobactam	2015
Ceftolozane-tazobactam: A new-generation cephalosporin. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2015, Dec-15, Volume: 72, Issue:24 Topics: Animals; Anti-Bacterial Agents; beta-Lactamase Inhibitors; Cephalosporins; Chemistry, Pharmaceutical; Clinical Trials as Topic; Humans; Penicillanic Acid; Tazobactam	2015
Ceftolozane/Tazobactam: A Review in Complicated Intra-Abdominal and Urinary Tract Infections. Drugs, 2016, Volume: 76, Issue:2 Topics: Anti-Bacterial Agents; Cephalosporins; Clinical Trials, Phase III as Topic; Humans; Intraabdominal Infections; Multicenter Studies as Topic; Penicillanic Acid; Tazobactam; Urinary Tract Infections	2016
A Meta-Analysis on Clinical Outcomes of Ceftolozane versus Piperacillin in Combination with Tazobactam in Patients with Complicated Urinary Tract Infections. BioMed research international, 2022, Volume: 2022 Topics: Anti-Bacterial Agents; Cephalosporins; Humans; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pyelonephritis; Tazobactam; Urinary Tract Infections	2022

Trials

7 trial(s) available for penicillanic acid and fr 264205

Article	Year
Population pharmacokinetics of ceftolozane/tazobactam in healthy volunteers, subjects with varying degrees of renal function and patients with bacterial infections. Journal of clinical pharmacology, 2015, Volume: 55, Issue:2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Cephalosporins; Female; Healthy Volunteers; Humans; Male; Middle Aged; Models, Biological; Penicillanic Acid; Renal Insufficiency; Tazobactam; Young Adult	2015
Ceftolozane/tazobactam pharmacokinetic/pharmacodynamic-derived dose justification for phase 3 studies in patients with nosocomial pneumonia. Journal of clinical pharmacology, 2016, Volume: 56, Issue:1 Topics: Adult; Anti-Bacterial Agents; Bronchoalveolar Lavage Fluid; Cephalosporins; Cross Infection; Drug Combinations; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Models, Biological; Monte Carlo Method; Penicillanic Acid; Pneumonia; Tazobactam; Young Adult	2016
Characteristics and Outcomes of Complicated Intra-abdominal Infections Involving Pseudomonas aeruginosa from a Randomized, Double-Blind, Phase 3 Ceftolozane-Tazobactam Study. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:7 Topics: Adult; Aged; Anti-Bacterial Agents; Cephalosporins; Double-Blind Method; Female; Humans; Intraabdominal Infections; Male; Metronidazole; Middle Aged; Penicillanic Acid; Pseudomonas aeruginosa; Tazobactam	2016
Does moderate renal impairment affect clinical outcomes in complicated intra-abdominal and complicated urinary tract infections? Analysis of two randomized controlled trials with ceftolozane/tazobactam. The Journal of antimicrobial chemotherapy, 2017, 03-01, Volume: 72, Issue:3 Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Cephalosporins; Female; Humans; Intraabdominal Infections; Male; Middle Aged; Penicillanic Acid; Renal Insufficiency; Tazobactam; Treatment Outcome; Urinary Tract Infections; Young Adult	2017
Analysis of patients with diabetes and complicated intra-abdominal infection or complicated urinary tract infection in phase 3 trials of ceftolozane/tazobactam. BMC infectious diseases, 2017, 05-02, Volume: 17, Issue:1 Topics: Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Cephalosporins; Diabetes Complications; Diabetes Mellitus; Female; Humans; Intraabdominal Infections; Levofloxacin; Male; Metronidazole; Middle Aged; Penicillanic Acid; Pyelonephritis; Tazobactam; Urinary Tract Infections	2017
Safety and Efficacy of Ceftolozane/Tazobactam Versus Meropenem in Neonates and Children With Complicated Urinary Tract Infection, Including Pyelonephritis: A Phase 2, Randomized Clinical Trial. The Pediatric infectious disease journal, 2023, 04-01, Volume: 42, Issue:4 Topics: Adult; Anti-Bacterial Agents; Cephalosporins; Child; Escherichia coli; Humans; Infant, Newborn; Meropenem; Penicillanic Acid; Pyelonephritis; Tazobactam; Urinary Tract Infections	2023
Safety and Efficacy of Ceftolozane/Tazobactam Plus Metronidazole Versus Meropenem From a Phase 2, Randomized Clinical Trial in Pediatric Participants With Complicated Intra-abdominal Infection. The Pediatric infectious disease journal, 2023, Jul-01, Volume: 42, Issue:7 Topics: Adult; Anti-Bacterial Agents; Cephalosporins; Child; Escherichia coli; Humans; Intraabdominal Infections; Meropenem; Metronidazole; Penicillanic Acid; Tazobactam	2023

Other Studies

49 other study(ies) available for penicillanic acid and fr 264205

Article	Year
In vitro potency of CXA-101, a novel cephalosporin, against Pseudomonas aeruginosa displaying various resistance phenotypes, including multidrug resistance. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1 Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Cephalosporins; Child; Child, Preschool; Cross Infection; Drug Combinations; Drug Resistance, Multiple, Bacterial; Humans; Infant; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Pseudomonas aeruginosa; Tazobactam; Young Adult	2010
Chequerboard titration of cephalosporin CXA-101 (FR264205) and tazobactam versus beta-lactamase-producing Enterobacteriaceae. The Journal of antimicrobial chemotherapy, 2010, Volume: 65, Issue:9 Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Enterobacteriaceae; Enzyme Inhibitors; Microbial Sensitivity Tests; Penicillanic Acid; Tazobactam	2010
Antimicrobial activity of CXA-101, a novel cephalosporin tested in combination with tazobactam against Enterobacteriaceae, Pseudomonas aeruginosa, and Bacteroides fragilis strains having various resistance phenotypes. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:5 Topics: Bacteroides fragilis; Cephalosporins; Drug Resistance, Bacterial; Enterobacteriaceae; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Tazobactam	2011
In vitro activity of CXA-101 plus tazobactam (CXA-201) against CTX-M-14- and CTX-M-15-producing Escherichia coli and Klebsiella pneumoniae. Diagnostic microbiology and infectious disease, 2011, Volume: 70, Issue:1 Topics: Anti-Bacterial Agents; Bacterial Typing Techniques; beta-Lactamases; Cephalosporins; Escherichia coli; Escherichia coli Infections; Genotype; Humans; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Typing; Penicillanic Acid; Tazobactam	2011
In vivo comparison of CXA-101 (FR264205) with and without tazobactam versus piperacillin-tazobactam using human simulated exposures against phenotypically diverse gram-negative organisms. Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:1 Topics: Animals; Anti-Bacterial Agents; beta-Lactamases; Cephalosporins; Colony Count, Microbial; Disease Models, Animal; Drug Combinations; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Female; Humans; Klebsiella Infections; Klebsiella pneumoniae; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Penicillanic Acid; Phenotype; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam; Thigh	2012
In vitro activity of ceftolozane-tazobactam against Pseudomonas aeruginosa isolates obtained from patients in Canadian hospitals in the CANWARD study, 2007 to 2012. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:11 Topics: Anti-Bacterial Agents; Canada; Ceftazidime; Cephalosporins; Cross Infection; Drug Combinations; Drug Resistance, Multiple, Bacterial; Hospitals; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Tazobactam	2013
Pharmacological basis of β-lactamase inhibitor therapeutics: tazobactam in combination with Ceftolozane. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:12 Topics: Anti-Bacterial Agents; beta-Lactamases; Cephalosporins; Colony Count, Microbial; Computer Simulation; Drug Administration Schedule; Drug Combinations; Drug Dosage Calculations; Escherichia coli; Escherichia coli Infections; Gene Expression; Half-Life; Humans; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Models, Statistical; Penicillanic Acid; Plasmids; Tazobactam	2013
Activity of ceftolozane-tazobactam against a broad spectrum of recent clinical anaerobic isolates. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:2 Topics: Anaerobiosis; Anti-Bacterial Agents; Bacteroides fragilis; Cephalosporins; Clostridium; Drug Combinations; Fusobacterium; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Gram-Positive Cocci; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Prevotella; Propionibacterium; Tazobactam	2014
Post-β-lactamase-inhibitor effect of tazobactam in combination with ceftolozane on extended-spectrum-β-lactamase-producing strains. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:4 Topics: Anti-Bacterial Agents; beta-Lactamases; Cephalosporins; Escherichia coli; Microbial Sensitivity Tests; Penicillanic Acid; Tazobactam	2014
Impact of renal function on the pharmacokinetics and safety of ceftolozane-tazobactam. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:4 Topics: Adolescent; Adult; Aged; Cephalosporins; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Penicillanic Acid; Prospective Studies; Tazobactam; Young Adult	2014
Pseudomonas aeruginosa ceftolozane-tazobactam resistance development requires multiple mutations leading to overexpression and structural modification of AmpC. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:6 Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Ceftazidime; Cephalosporins; Imipenem; Meropenem; Microbial Sensitivity Tests; Mutation; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam; Thienamycins	2014
Antimicrobial activity of ceftolozane/tazobactam tested against Pseudomonas aeruginosa and Enterobacteriaceae with various resistance patterns isolated in European hospitals (2011-12). The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:10 Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamase Inhibitors; Cephalosporins; Cross Infection; Enterobacteriaceae; Enterobacteriaceae Infections; Europe; Genotype; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam	2014
Relationship between ceftolozane-tazobactam exposure and selection for Pseudomonas aeruginosa resistance in a hollow-fiber infection model. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:10 Topics: Anti-Bacterial Agents; Cephalosporins; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Tazobactam	2014
In vivo efficacy of ceftolozane against Pseudomonas aeruginosa in a rabbit experimental model of pneumonia: comparison with ceftazidime, piperacillin/tazobactam and imipenem. International journal of antimicrobial agents, 2014, Volume: 44, Issue:3 Topics: Animal Structures; Animals; Anti-Bacterial Agents; Bacterial Load; Ceftazidime; Cephalosporins; Colony Count, Microbial; Disease Models, Animal; Female; Humans; Imipenem; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Rabbits; Treatment Outcome	2014
Ceftolozane/tazobactam for the treatment of complicated urinary tract and intra-abdominal infections. Future microbiology, 2015, Volume: 10, Issue:2 Topics: Animals; beta-Lactamase Inhibitors; Cephalosporins; Clinical Trials as Topic; Enterobacteriaceae; Escherichia coli; Gram-Negative Bacterial Infections; Humans; Intraabdominal Infections; Investigational New Drug Application; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Tazobactam; Treatment Outcome; Urinary Tract Infections	2015
Plasma and epithelial lining fluid pharmacokinetics of ceftolozane and tazobactam alone and in combination in mice. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:6 Topics: Animals; Anti-Bacterial Agents; Cephalosporins; Escherichia coli; Female; Klebsiella pneumoniae; Mice; Penicillanic Acid; Protein Binding; Tazobactam; Thigh	2015
In Vitro Activity of Ceftolozane Alone and in Combination with Tazobactam against Extended-Spectrum-β-Lactamase-Harboring Enterobacteriaceae. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:8 Topics: Anti-Bacterial Agents; beta-Lactamases; Cephalosporins; Drug Therapy, Combination; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Tazobactam	2015
Susceptibility Profile of Ceftolozane/Tazobactam and Other Parenteral Antimicrobials Against Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa From US Hospitals. Clinical therapeutics, 2015, Jul-01, Volume: 37, Issue:7 Topics: Adult; Anti-Infective Agents; beta-Lactamases; Cefepime; Cephalosporins; Cross Infection; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Enterobacteriaceae; Escherichia coli; Hospitals; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Pseudomonas aeruginosa; Tazobactam; United States	2015
Ceftolozane-tazobactam activity against phylogenetically diverse Clostridium difficile strains. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:11 Topics: Anti-Bacterial Agents; Cephalosporins; Clostridioides difficile; Microbial Sensitivity Tests; Penicillanic Acid; Phylogeny; Tazobactam	2015
Pharmacodynamics of Ceftolozane plus Tazobactam Studied in an In Vitro Pharmacokinetic Model of Infection. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:1 Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Bioreactors; Cephalosporins; Chromatography, High Pressure Liquid; Colony Count, Microbial; Computer Simulation; Escherichia coli; Gene Expression; Half-Life; Infusion Pumps; Microbial Sensitivity Tests; Models, Statistical; Penicillanic Acid; Porins; Pseudomonas aeruginosa; Tazobactam	2016
Prescribing Ceftolozane/Tazobactam for Pediatric Patients: Current Status and Future Implications. Paediatric drugs, 2016, Volume: 18, Issue:1 Topics: Anti-Bacterial Agents; Cephalosporins; Child; Humans; Intraabdominal Infections; Penicillanic Acid; Tazobactam	2016
Ceftolozane-Tazobactam Pharmacokinetics in a Critically Ill Patient on Continuous Venovenous Hemofiltration. Antimicrobial agents and chemotherapy, 2015, Dec-28, Volume: 60, Issue:3 Topics: Anti-Bacterial Agents; Cephalosporins; Critical Illness; Drug Resistance, Multiple, Bacterial; Hemofiltration; Humans; Intensive Care Units; Male; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Prospective Studies; Prosthesis-Related Infections; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam	2015
Evaluation of the In Vitro Activity of Ceftazidime-Avibactam and Ceftolozane-Tazobactam against Meropenem-Resistant Pseudomonas aeruginosa Isolates. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:5 Topics: Azabicyclo Compounds; Ceftazidime; Cephalosporins; Drug Combinations; Drug Resistance, Bacterial; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Tazobactam; Thienamycins	2016
Development of an HPLC Method for the Determination of Ceftolozane/Tazobactam in Biological and Aqueous Matrixes. Journal of chromatographic science, 2016, Volume: 54, Issue:6 Topics: Animals; Anti-Bacterial Agents; Cephalosporins; Chemistry Techniques, Analytical; Chromatography, High Pressure Liquid; Humans; Penicillanic Acid; Plasma; Reproducibility of Results; Sodium Chloride; Swine; Tazobactam	2016
Daptomycin in Combination with Ceftolozane-Tazobactam or Cefazolin against Daptomycin-Susceptible and -Nonsusceptible Staphylococcus aureus in an In Vitro, Hollow-Fiber Model. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:7 Topics: Anti-Bacterial Agents; Cefazolin; Cephalosporins; Daptomycin; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Penicillanic Acid; Staphylococcus aureus; Tazobactam	2016
Use of Ceftolozane/Tazobactam in the Treatment of Multidrug-resistant Pseudomonas aeruginosa Bloodstream Infection in a Pediatric Leukemia Patient. The Pediatric infectious disease journal, 2016, Volume: 35, Issue:9 Topics: Anti-Bacterial Agents; Bacteremia; Cephalosporins; Child; Drug Resistance, Multiple, Bacterial; Hospitalization; Humans; Leukemia; Male; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam	2016
Successful treatment of multidrug-resistant Pseudomonas aeruginosa breakthrough bacteremia with ceftolozane/tazobactam. Infection, 2017, Volume: 45, Issue:1 Topics: Anti-Bacterial Agents; Bacteremia; Cephalosporins; Drug Resistance, Multiple, Bacterial; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Off-Label Use; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam	2017
Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:4 Topics: Achromobacter denitrificans; Anti-Bacterial Agents; Ceftazidime; Cephalosporins; Cystic Fibrosis; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacteria; Humans; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Stenotrophomonas maltophilia; Tazobactam; Thienamycins	2017
Ex vivo Ceftolozane/Tazobactam Clearance during Continuous Renal Replacement Therapy. Blood purification, 2017, Volume: 44, Issue:1 Topics: Animals; Anti-Bacterial Agents; Cattle; Cephalosporins; Drug Dosage Calculations; Hemodialysis Solutions; Humans; Membranes, Artificial; Metabolic Clearance Rate; Models, Biological; Penicillanic Acid; Renal Replacement Therapy; Tazobactam	2017
Multicenter Evaluation of Ceftolozane/Tazobactam for Serious Infections Caused by Carbapenem-Resistant Pseudomonas aeruginosa. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2017, 07-01, Volume: 65, Issue:1 Topics: Adult; Aged; Anti-Bacterial Agents; Carbapenems; Cephalosporins; Female; Humans; Male; Middle Aged; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Tazobactam	2017
Cost-effectiveness of ceftolozane/tazobactam compared with piperacillin/tazobactam as empiric therapy based on the in-vitro surveillance of bacterial isolates in the United States for the treatment of complicated urinary tract infections. BMC infectious diseases, 2017, 04-28, Volume: 17, Issue:1 Topics: Adult; Anti-Bacterial Agents; Cephalosporins; Cost-Benefit Analysis; Hospitalization; Humans; Middle Aged; Monte Carlo Method; Mortality; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Quality-Adjusted Life Years; United States; Urinary Tract Infections	2017
Ceftolozane-Tazobactam Activity against Pseudomonas aeruginosa Clinical Isolates from U.S. Hospitals: Report from the PACTS Antimicrobial Surveillance Program, 2012 to 2015. Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:7 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Cephalosporins; Drug Resistance, Multiple, Bacterial; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Tazobactam; United States	2017
Monotherapy of ceftazidime-avibactam and ceftolozane-tazobactam: two effective antimicrobial agents against multidrug-resistant organisms except for NDM-1 isolates. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2017, Volume: 62 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Azabicyclo Compounds; beta-Lactamases; Ceftazidime; Cephalosporins; Drug Combinations; Penicillanic Acid; Tazobactam	2017
Monotherapy of ceftazidime-avibactam and ceftolozane-tazobactam against multidrug-resistant organisms. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2017, Volume: 62 Topics: Azabicyclo Compounds; Ceftazidime; Cephalosporins; Drug Combinations; Penicillanic Acid; Tazobactam	2017
Ceftolozane-Tazobactam for the Treatment of Multidrug-Resistant Pseudomonas aeruginosa Infections: Clinical Effectiveness and Evolution of Resistance. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2017, 07-01, Volume: 65, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cephalosporins; Drug Resistance, Multiple, Bacterial; Female; Genome, Bacterial; Humans; Male; Middle Aged; Penicillanic Acid; Pennsylvania; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Tazobactam; Young Adult	2017
Antimicrobial Activity of Ceftolozane-Tazobactam Tested Against Enterobacteriaceae and Pseudomonas aeruginosa with Various Resistance Patterns Isolated in U.S. Hospitals (2013-2016) as Part of the Surveillance Program: Program to Assess Ceftolozane-Tazoba Microbial drug resistance (Larchmont, N.Y.), 2018, Volume: 24, Issue:5 Topics: Amikacin; Anti-Bacterial Agents; Cephalosporins; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Hospitals; Humans; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam; Thienamycins	2018
Validated HPLC-UV detection method for the simultaneous determination of ceftolozane and tazobactam in human plasma. Bioanalysis, 2018, Apr-01, Volume: 10, Issue:7 Topics: Anti-Bacterial Agents; Cephalosporins; Chromatography, High Pressure Liquid; Humans; Penicillanic Acid; Plasma; Tazobactam	2018
Ceftolozane/tazobactam sensitivity patterns in Pseudomonas aeruginosa isolates recovered from sputum of cystic fibrosis patients. Diagnostic microbiology and infectious disease, 2018, Volume: 92, Issue:1 Topics: Adult; Anti-Bacterial Agents; Cephalosporins; Cross Infection; Cystic Fibrosis; Drug Resistance, Multiple, Bacterial; Female; Humans; Male; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Sputum; Tazobactam	2018
Ceftolozane/Tazobactam vs Polymyxin or Aminoglycoside-based Regimens for the Treatment of Drug-resistant Pseudomonas aeruginosa. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020, 07-11, Volume: 71, Issue:2 Topics: Aminoglycosides; Anti-Bacterial Agents; Cephalosporins; Drug Resistance, Multiple, Bacterial; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Pharmaceutical Preparations; Polymyxins; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Tazobactam	2020
Low pH reduces the activity of ceftolozane/tazobactam in human urine, but confirms current breakpoints for urinary tract infections. The Journal of antimicrobial chemotherapy, 2020, 03-01, Volume: 75, Issue:3 Topics: Anti-Bacterial Agents; Cephalosporins; Humans; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Tazobactam; Urinary Tract Infections	2020
Susceptibility trends of ceftolozane/tazobactam and comparators when tested against European Gram-negative bacterial surveillance isolates collected during 2012-18. The Journal of antimicrobial chemotherapy, 2020, 10-01, Volume: 75, Issue:10 Topics: Anti-Bacterial Agents; Cephalosporins; Cross Infection; Drug Resistance, Multiple, Bacterial; Europe; Europe, Eastern; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam	2020
Continuous infusion of ceftolozane-tazobactam resulted in high cerebrospinal fluid concentrations of ceftolozane in a patient with multidrug-resistant Pseudomonas aeruginosa meningitis. Infection, 2021, Volume: 49, Issue:2 Topics: Anti-Bacterial Agents; Cephalosporins; Drug Resistance, Multiple, Bacterial; Humans; Meningitis; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam	2021
What place does ceftolozane/tazobactam have in the treatment of complicated urinary-tract infections? Expert opinion on pharmacotherapy, 2021, Volume: 22, Issue:11 Topics: Anti-Bacterial Agents; Cephalosporins; Drug Resistance, Multiple, Bacterial; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam; Urinary Tract Infections	2021
Plasma and soft tissue pharmacokinetics of ceftolozane/tazobactam in healthy volunteers after single and multiple intravenous infusion: a microdialysis study. The Journal of antimicrobial chemotherapy, 2021, 08-12, Volume: 76, Issue:9 Topics: Anti-Bacterial Agents; Cephalosporins; Healthy Volunteers; Humans; Infusions, Intravenous; Microbial Sensitivity Tests; Microdialysis; Penicillanic Acid; Prospective Studies; Pseudomonas aeruginosa; Tazobactam	2021
Ceftolozane/tazobactam for refractory P. aeruginosa endocarditis: A case report and pharmacokinetic analysis. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2022, Volume: 28, Issue:1 Topics: Anti-Bacterial Agents; Cephalosporins; Endocarditis; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam	2022
Activity of Ceftolozane-Tazobactam Against Gram-Negative Isolates from Australia and New Zealand as part of the PACTS Surveillance 2016-2018. Journal of global antimicrobial resistance, 2022, Volume: 31 Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; Cephalosporins; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Meropenem; Microbial Sensitivity Tests; New Zealand; Penicillanic Acid; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Tazobactam	2022
In vitro activity of ceftolozane/tazobactam against multidrug-resistant Pseudomonas aeruginosa from patients in Western Europe: SMART 2017-2020. International journal of antimicrobial agents, 2023, Volume: 61, Issue:5 Topics: Anti-Bacterial Agents; Anti-Infective Agents; beta-Lactamases; Ceftazidime; Cephalosporins; Drug Resistance, Multiple, Bacterial; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam	2023
Susceptibility of ceftolozane/tazobactam against multidrug-resistant and carbapenem-resistant Pseudomonas aeruginosa. The new microbiologica, 2023, Volume: 46, Issue:2 Topics: Anti-Bacterial Agents; Carbapenems; Cephalosporins; Drug Resistance, Multiple, Bacterial; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam	2023
Efficacy and safety of tazobactam/ceftolozane in combination with metronidazole for intraabdominal infection in a hepato-biliary-pancreatic field in clinical practice. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2023, Volume: 29, Issue:9 Topics: Anti-Bacterial Agents; Cephalosporins; Humans; Intraabdominal Infections; Metronidazole; Penicillanic Acid; Tazobactam	2023