Page last updated: 2024-08-17

penicillanic acid and amdinocillin

penicillanic acid has been researched along with amdinocillin in 145 studies

Research

Studies (145)

TimeframeStudies, this research(%)All Research%
pre-1990144 (99.31)18.7374
1990's0 (0.00)18.2507
2000's1 (0.69)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bundgaard, H1
Carlqvist, J; Theodorsen, A; Westerlund, D1
Baltzer, B; Lund, F; Rastrup-Andersen, N1
Chattopadhyay, B; Thomas, E1
Bakhtiar, M; Selwyn, S1
Anderson, JD; Eftekhar, F2
Adams, MA; Anderson, JD; Smith, L; Webster, HM1
Koser, C; Mielenz, H; Roser, H1
Iwaya, M; Jones, CW; Khorana, J; Strominger, JL1
Gray, J1
Adams, MA; Anderson, JD; Shepherd, CA; Wilson, LC1
Brumfitt, W; Hamilton-Miller, JM; Kerry, DW1
Ball, AP; Mitchard, M; Viswan, AK; Wise, R1
Spratt, BG1
Borowski, J; Busko-Oszczapowicz, I; Cieslak, J; Zaremba, M1
Nye, FJ; Roberts, C1
Adams, MA; Anderson, JD1
Frimodt-Møller, N; Ravn, TJ1
Aono, R; Tamura, G; Yamasaki, M1
Brennand, J; Ironside, AG; Mandal, BK1
Gmeiner, J; Martin, HH1
Borowski, J; Bortnik-Kozikowska, B; Kacprzak-Wiatr, A; Piotrowski, J; Zaremba, M; Zukowska-Nytko, K1
Bischof-Léger, E; Helm, EB; Stille, W1
Kosakai, N; Oguri, T1
Bergan, T; Engeset, A; Olszewski, W; Solberg, R1
Chattopadhyay, B; Hall, I1
Adamska-Dyniewska, H; Denys, A; Gajewska, B; Małafiej, E; Pieloch, Z; Schaeffer, A; Tkaczewski, W; Zdziarska, H1
Fink, FN; Fletcher, DD; Sande, MA; Scheld, WM1
Kaye, D; Levison, ME; Trestman, I1
Ahlstedt, S; Sandberg, T; Stenqvist, K; Svanborg-Edén, C1
Marsh, BT; Menday, AP3
Geddes, AM; McKendrick, MW1
Hagel, RB; Humphrey, D; Waysek, EH1
Piot, P; van Dyck, E1
Houben, AW; Stobberingh, EE; van Boven, CP1
Farrar, WE1
Celozzi, E; Gadebusch, HH; Pelak, BA; Stapley, EO1
Carlqvist, J; Ovesson, M; Pring, BG; Westerlund, D1
Buchanan, CE; Coyette, J; McDowell, TD; Shockman, GD; Swavely, TS1
Matsuhashi, M; Matsuzawa, H; Tamaki, S1
Habte, D; Stintzing, G; Thorén, A; Wadström, T; Wolde-Mariam, T1
Cronberg, S; Ekwall, E; Ganrot-Norlin, K; Jonsson, M; Juhlin, I; Kahlmeter, G; Scheja, A; Thorén, A; Thulin, KE; Tunevall, G1
Botta, G; Canepari, P; Fontana, R; Satta, G2
de Silva, JA; Strojny, N1
Melby, K; Rollag, H1
Bergan, T1
García-Iglesias, MC; Palomares, JC; Perea, EJ1
Bongaerts, GP; Bruggeman-Ogle, K1
Foley, M; Hone, R1
Deguchi, K1
McCarthy, LR; Steinkraus, GE1
Coppens, L; Klastersky, J; Menday, AP; Meunier-Carpentier, F1
Bailey, K; Bisson, PG; Cruickshank, JG; Radford, BL1
Rahman, M1
Bongaerts, GP; Bruggeman-Ogle, KM1
Svarva, PL; Wessel-Aas, T1
Thorén, A1
Aird, MY; Anderson, JD; Eftekhar, F; Morrison, BJ1
Frimodt-Møller, N; Madsen, PO; Maigaard, S1
Khorasani, MH; Menday, AP; Pines, A; Raafat, H; Sharma, JC1
Barbour, AG; Mayer, LW; Spratt, BG1
Fass, RJ2
Barriere, SL; Conte, JE; Gambertoglio, JG; Lin, ET3
de Louvois, J; Hurley, R; Mulhall, A1
Onoe, T; Sagawa, H; Suginaka, H; Umemoto, T1
Harwood, CR; Scott, NW1
Buśko-Oszczapowicz, I; Cieślak, J; Gluziński, P; Krajewski, JW; Lebioda, L; Urbańczyk-Lipkowska, Z1
Kondo, M; Tsuchiya, K1
Otsuki, M1
Arnold, K; Chau, PY; Ling, J; Ng, WS1
Anderson, JD; Beskid, G; Cleeland, R; Eftekhar, F; Kramer, MJ1
Baumueller, A; Frimodt-Moeller, N; Hoyme, U; Madsen, PO; Maigaard, S; Nielsen, OS1
Gaunt, H; Taylor, PW; Unger, FM1
Juhlin, I; Winblad, S1
Shimizu, Y1
Swiderska-Kulikowa, B; Zaleski, A1
Brooks, MA; Lee, TL1
Buśko-Oszczapowicz, I; Całka, A; Cieślak, J; Kotula, W; Marchlewska, Z; Prussak-Wieckowska, T; Rogowska, W; Sadowska, J; Stepniak, M1
Bergan, T; Bielecki, T; Fuglesang, JE; Namork, E; Naterstad, A1
Frère, JM; Ghuysen, JM; Kelly, JA; Klein, D1
Jertborn, M; Lidin-Janson, G; Martinell, J; Norkrans, G; Trollfors, B1
Svarva, P; Wessel-Aas, T1
Berenguer, J; de Pedro, MA; Vázquez, D2
Burdon, DW; Hares, MM; Hegarty, A; Keighley, MR; Tomkyns, J1
Beskid, G; Cleeland, R; Grimm, LM; McCracken, GH; Nelson, JD; Schaad, UB1
MacLaren, DM; Namavar, F; Smit, AM; Sparrius, M; Verweij-van Vught, AM1
Christensen, OE; Limson, BM; Liwanag, E; Menday, P; Mendoza, MT1
Bertermann, H; Seppelt, U; Sonntag, HG1
Hansson, HB; Juhlin, I; Walder, M1
Butler, T; Dixon, P; Shuster, CW1
Neu, HC2
Carlqvist, J; Pettersson, B; Westerlund, D1
borowski, J; Grala-Kałuzna, A; Kacprzak-Wiatr, A; Kulikowska, A; Piotrowski, J; Zaremba, M; Zukowska-Nytko, K1
Borowski, J; Zaremba, M; Zukowska-Nytko, K2
Kowalewska, E; Lipnicki, D; Osowiecki, H; Zawisza-Zenkteler, W1
Essig, P; Gmeiner, J; Martin, HH1
Bergan, T; Josefsson, K; Magni, L; Pring, BG; Westerlund, D1
Ishino, F; Matsuhashi, M; Spratt, BG; Tamaki, S1
Granlund, M; Henning, C; Landgren, E1
Mattie, H; van der Voet, GB; van Furth, R2
Babiuch, L; Dziubek, Z; Janeczko, J; Narebski, J; Olejnik, Z; Pokrzywnicka, T1
Black, FT; Christensen, O; Gaarslev, K; Orskov, F; Orskov, I; Stenderup, A; Stenderup, J1
Mhalu, FS; Runyoro, D; Shao, JF; Swai, V1
File, TM; Tan, JS1
Green, EA; Hall, S; Hanna, CE; Sattler, FR1
Bodey, GP; Estey, EH; Lawson, RD1
de Louvois, J; Mulhall, A1
Kusmiesz, H; Nelson, JD; Shelton, S1
Ball, AP; Geddes, AM1
Cleeland, R; Squires, E1
Cleeland, R; Kramer, MJ; Mauriz, YR; Robertson, TL; Timmes, MD1
Gordin, FM; Sande, MA1
Christenson, JG; Francke, EL; Neu, HC; Ortiz-Neu, C; Srinivasan, S1
File, TM; Salstrom, SJ; Tan, JS1
Demos, CH; Green, E1
Cox, CE1
Amon, MB; Krause, LK; Ward, TT1
Beam, TR; King, JW; Neu, HC; Smith, LG1
Farrar, WE; Rotstein, C1
Hirschman, SZ; Jacobson, J; Masci, J; Meyers, BR; Srulevitch, E1
Babiuch, L; Bireta, K; Dziubek, Z; Janeczko, J; Olejnik, Z; Scheffer, A1
Khantimer, EI1
Botta, G; Canepari, P; Satta, G1
Orskov, F; Orskov, I; Stenderup, J1
Jacobsen, J; Stintzing, G1
Christensen, O; Menday, P; Pescante, M; Santiago, L; Uylangco, C1
Kowalewska, E; Osowiecki, H; Zawisza-Zenkteler, W1
Dabernat, H; Delmas, C; Lareng, MB1
Debbia, EA; Gualco, L; Maioli, E; Marchese, A1

Reviews

4 review(s) available for penicillanic acid and amdinocillin

ArticleYear
Serum levels of mecillinam in patients with severely impaired renal function.
    Scandinavian journal of infectious diseases, 1980, Volume: 12, Issue:4

    Topics: Amdinocillin; Female; Humans; Kidney Failure, Chronic; Male; Penicillanic Acid; Urinary Tract Infections

1980
Amdinocillin therapy of experimental animal infections.
    The American journal of medicine, 1983, Aug-29, Volume: 75, Issue:2A

    Topics: Amdinocillin; Animals; Anti-Bacterial Agents; Bacterial Infections; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Escherichia coli Infections; Klebsiella Infections; Klebsiella pneumoniae; Meningitis; Penicillanic Acid

1983
Review of clinical experience with amdinocillin monotherapy and comparative studies.
    The American journal of medicine, 1983, Aug-29, Volume: 75, Issue:2A

    Topics: Adolescent; Adult; Aged; Amdinocillin; Anti-Bacterial Agents; Bacterial Infections; Child; Cholecystitis; Clinical Trials as Topic; Diarrhea; Endocarditis, Bacterial; Enterobacteriaceae Infections; Female; Humans; Male; Middle Aged; Penicillanic Acid; Sepsis; Typhoid Fever; Urinary Tract Infections

1983
Penicillin-binding proteins and role of amdinocillin in causing bacterial cell death.
    The American journal of medicine, 1983, Aug-29, Volume: 75, Issue:2A

    Topics: Amdinocillin; Anti-Bacterial Agents; Bacteria; Bacterial Proteins; beta-Lactamases; Binding, Competitive; Carrier Proteins; Cell Wall; Drug Interactions; Hexosyltransferases; Muramoylpentapeptide Carboxypeptidase; Penicillanic Acid; Penicillin-Binding Proteins; Peptidyl Transferases

1983

Trials

18 trial(s) available for penicillanic acid and amdinocillin

ArticleYear
Urinary excretion of mecillinam by volunteers receiving film-coated tablets of pivmecillinam hydrochloride.
    Chemotherapy, 1979, Volume: 25, Issue:1

    Topics: Administration, Oral; Amdinocillin; Amdinocillin Pivoxil; Clinical Trials as Topic; Dyspepsia; Half-Life; Humans; Penicillanic Acid; Tablets

1979
Mecillinam in enteric fever.
    British medical journal, 1979, Mar-03, Volume: 1, Issue:6163

    Topics: Administration, Oral; Adolescent; Adult; Amdinocillin; Child; Clinical Trials as Topic; Female; Humans; Injections, Intramuscular; Male; Microbial Sensitivity Tests; Penicillanic Acid; Time Factors; Typhoid Fever

1979
Antibiotics in the treatment of gastroenteritis caused by enteropathogenic Escherichia coli.
    The Journal of infectious diseases, 1980, Volume: 141, Issue:1

    Topics: Amdinocillin; Clinical Trials as Topic; Escherichia coli; Escherichia coli Infections; Female; Gastroenteritis; Humans; Infant; Infant, Newborn; Male; Penicillanic Acid; Serotyping; Sulfamethoxazole; Trimethoprim

1980
Comparative efficacy of 3-day and 7-day chemotherapy with pivmecillinam in urinary tract infections in general practice.
    The Journal of international medical research, 1980, Volume: 8, Issue:2

    Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Amdinocillin; Amdinocillin Pivoxil; Bacteriuria; Clinical Trials as Topic; Cystitis; Family Practice; Female; Humans; Middle Aged; Penicillanic Acid

1980
Mecillinam and ampicillin separately or combined in gram-negative septicemia.
    Infection, 1980, Volume: 8, Issue:1

    Topics: Adult; Aged; Amdinocillin; Ampicillin; Drug Therapy, Combination; Enterobacteriaceae; Enterobacteriaceae Infections; Exanthema; Female; Half-Life; Humans; Kinetics; Male; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Sepsis

1980
Carbenicillin plus cefazolin with or without mecillinam as an early treatment of bacteremia caused by gram-negative organisms: randomized double-blind study.
    Antimicrobial agents and chemotherapy, 1980, Volume: 18, Issue:3

    Topics: Amdinocillin; Carbenicillin; Cefazolin; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Neoplasms; Penicillanic Acid; Random Allocation; Sepsis

1980
Mecillinam (Selexidin) in the treatment of neonates.
    Journal of perinatal medicine, 1981, Volume: 9, Issue:2

    Topics: Amdinocillin; Clinical Trials as Topic; Drug Therapy, Combination; Female; Half-Life; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; Penicillanic Acid; Penicillins; Sepsis

1981
Mecillinam versus cephaloridine for the treatment of acute pyelonephritis.
    Infection, 1982, Volume: 10, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Aged; Amdinocillin; Cephaloridine; Clinical Trials as Topic; Enterobacteriaceae; Female; Humans; Male; Middle Aged; Penicillanic Acid; Pyelonephritis

1982
Randomised, comparative trial of mecillinam, mecillinam/ampicillin and chloramphenicol in the treatment of enteric fever.
    The Journal of antimicrobial chemotherapy, 1982, Volume: 9, Issue:5

    Topics: Adolescent; Adult; Amdinocillin; Ampicillin; Chloramphenicol; Clinical Trials as Topic; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Random Allocation; Salmonella; Typhoid Fever

1982
[Comparative study on clinical effectiveness of mecillinam and pivmecillinam versus ampicillin in acute urinary infections (author's transl)].
    Arzneimittel-Forschung, 1982, Volume: 32, Issue:5

    Topics: Amdinocillin; Amdinocillin Pivoxil; Ampicillin; Drug Therapy, Combination; Humans; Penicillanic Acid; Urinary Tract Infections

1982
Pharmacokinetics of bacmecillinam and pivmecillinam in volunteers.
    European journal of clinical pharmacology, 1982, Volume: 23, Issue:3

    Topics: Absorption; Adult; Amdinocillin; Amdinocillin Pivoxil; Biological Availability; Chromatography, High Pressure Liquid; Fasting; Half-Life; Humans; Kinetics; Male; Penicillanic Acid; Random Allocation

1982
Mecillinam, a new prophylactic for travellers' diarrhoea. A prospective double-blind study in tourists travelling to Egypt and the Far East.
    Scandinavian journal of infectious diseases, 1983, Volume: 15, Issue:2

    Topics: Administration, Oral; Adult; Aged; Amdinocillin; Asia, Eastern; Diarrhea; Double-Blind Method; Doxycycline; Egypt; Escherichia coli; Escherichia coli Infections; Feces; Humans; Middle Aged; Penicillanic Acid; Penicillin Resistance; Prospective Studies; Salmonella; Salmonella Infections; Travel

1983
Amdinocillin plus cefoxitin versus cefoxitin alone in therapy of mixed soft tissue infections (including diabetic foot infections).
    The American journal of medicine, 1983, Aug-29, Volume: 75, Issue:2A

    Topics: Adult; Aged; Amdinocillin; Bacterial Infections; Cefoxitin; Connective Tissue Diseases; Diabetes Complications; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Male; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Random Allocation

1983
Efficacy of amdinocillin and lack of nephrotoxicity when combined with a second beta-lactam antibiotic for therapy of serious gram-negative bacillary infections.
    The American journal of medicine, 1983, Aug-29, Volume: 75, Issue:2A

    Topics: Adult; Aged; Amdinocillin; Anti-Bacterial Agents; Drug Therapy, Combination; Enterobacteriaceae Infections; Female; Gentamicins; Humans; Kidney Diseases; Male; Middle Aged; Penicillanic Acid; Random Allocation; Tobramycin

1983
Randomized trial of cefamandole plus amdinocillin versus cefamandole in serious pediatric infections.
    The American journal of medicine, 1983, Aug-29, Volume: 75, Issue:2A

    Topics: Amdinocillin; Bacterial Infections; Cefamandole; Cephalosporins; Child; Child, Preschool; Clinical Trials as Topic; Drug Synergism; Drug Therapy, Combination; Humans; Infant; Microbial Sensitivity Tests; Pediatrics; Penicillanic Acid; Random Allocation

1983
Review of clinical experience with amdinocillin monotherapy and comparative studies.
    The American journal of medicine, 1983, Aug-29, Volume: 75, Issue:2A

    Topics: Adolescent; Adult; Aged; Amdinocillin; Anti-Bacterial Agents; Bacterial Infections; Child; Cholecystitis; Clinical Trials as Topic; Diarrhea; Endocarditis, Bacterial; Enterobacteriaceae Infections; Female; Humans; Male; Middle Aged; Penicillanic Acid; Sepsis; Typhoid Fever; Urinary Tract Infections

1983
Changes in serotype and resistance pattern of the intestinal Escherichia coli flora during travel. Results from a trial of mecillinam as a prophylactic against travellers' diarrhoea.
    Scandinavian journal of infectious diseases, 1983, Volume: 15, Issue:4

    Topics: Adult; Aged; Amdinocillin; Anti-Bacterial Agents; Denmark; Diarrhea; Escherichia coli; Female; Humans; Intestines; Male; Middle Aged; Penicillanic Acid; Penicillin Resistance; Serotyping; Travel

1983
Pivmecillinam, co-trimoxazole and oral mecillinam in gastroenteritis due to Vibrio spp.
    The Journal of antimicrobial chemotherapy, 1984, Volume: 13, Issue:2

    Topics: Adult; Amdinocillin; Amdinocillin Pivoxil; Child, Preschool; Cholera; Drug Combinations; Enterobacteriaceae Infections; Gastroenteritis; Humans; Penicillanic Acid; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Vibrio Infections; Vibrio parahaemolyticus

1984

Other Studies

124 other study(ies) available for penicillanic acid and amdinocillin

ArticleYear
Aminolysis of the 6 beta-amidinopenicillanic acid mecillinam. Imidazolone formation and intramolecular participation of the amidino side-chain.
    Acta pharmaceutica Suecica, 1977, Volume: 14, Issue:3

    Topics: Amdinocillin; Amines; Antigens; Benzylamines; Chemical Phenomena; Chemistry; Hydrogen-Ion Concentration; Imidazoles; Mathematics; Penicillanic Acid; Penicillin G

1977
Analysis of penicillins in biological material by reversed phase liquid chromatography and post-column derivatization.
    Acta pharmaceutica Suecica, 1979, Volume: 16, Issue:3

    Topics: Amdinocillin; Ampicillin; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Chromatography, Liquid; Hydrogen-Ion Concentration; Methods; Penicillanic Acid

1979
Degradation of mecillinam in aqueous solution.
    Journal of pharmaceutical sciences, 1979, Volume: 68, Issue:10

    Topics: Acids; Alkalies; Amdinocillin; Chemical Phenomena; Chemistry; Drug Stability; Half-Life; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Penicillanic Acid

1979
Mecillinam.
    Lancet (London, England), 1976, Sep-04, Volume: 1, Issue:7984

    Topics: Amdinocillin; Penicillanic Acid; Penicillin Resistance

1976
In-vitro sensitivity to mecillinam of multiresistant gram-negative rods.
    Lancet (London, England), 1978, Jan-28, Volume: 1, Issue:8057

    Topics: Acinetobacter; Amdinocillin; Bacteriuria; Enterobacteriaceae; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Penicillanic Acid; Penicillin Resistance; Wound Infection

1978
Mecillinam.
    Lancet (London, England), 1978, Feb-04, Volume: 1, Issue:8058

    Topics: Amdinocillin; Drug Evaluation; Humans; Penicillanic Acid; Urinary Tract Infections

1978
Mecillinam.
    Lancet (London, England), 1978, Feb-11, Volume: 1, Issue:8059

    Topics: Amdinocillin; Ampicillin; Carbenicillin; Cephaloridine; Enterobacteriaceae; In Vitro Techniques; Microbial Sensitivity Tests; Penicillanic Acid; Penicillin Resistance

1978
Sensitivity of urinary-tract isolates to mecillinam and amoxycillin.
    Lancet (London, England), 1978, Feb-25, Volume: 1, Issue:8061

    Topics: Amdinocillin; Amoxicillin; Ampicillin; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Penicillanic Acid; Penicillin Resistance; Urinary Tract Infections

1978
Laboratory sensitivity or clinical efficacy.
    Lancet (London, England), 1978, Mar-18, Volume: 1, Issue:8064

    Topics: Amdinocillin; Drug Evaluation; Penicillanic Acid; Penicillin Resistance

1978
Growth properties of mecillinam-resistant bacterial variants in urine.
    Antimicrobial agents and chemotherapy, 1977, Volume: 12, Issue:5

    Topics: Amdinocillin; Culture Media; Enterobacteriaceae; Genetic Variation; Humans; In Vitro Techniques; Penicillanic Acid; Penicillin Resistance; Phenotype; Time Factors; Urine

1977
Plotting regression lines for a new beta-lactam antibiotic (mecillinam).
    International journal of clinical pharmacology and biopharmacy, 1977, Volume: 15, Issue:11

    Topics: Amdinocillin; Bacteria; Culture Media; Microbial Sensitivity Tests; Penicillanic Acid; Regression Analysis; Time Factors

1977
Mapping of the mecillinam-resistant, round morphological mutants of Escherichia coli.
    Journal of bacteriology, 1978, Volume: 133, Issue:1

    Topics: Amdinocillin; Chromosome Mapping; Escherichia coli; Genes; Mutation; Penicillanic Acid; Penicillin Resistance; Phenotype; Transduction, Genetic

1978
Synergy and mecillinam.
    The Journal of antimicrobial chemotherapy, 1977, Volume: 3, Issue:6

    Topics: Amdinocillin; Ampicillin; Bacteria; Bacterial Infections; Bronchitis; Drug Synergism; Humans; Microbial Sensitivity Tests; Penicillanic Acid

1977
Studies on the effect of mecillinam upon Micrococcaceae and faecal streptococci under conditions simulating urinary tract infection.
    The Journal of antimicrobial chemotherapy, 1976, Volume: 2, Issue:4

    Topics: Adult; Amdinocillin; Amdinocillin Pivoxil; Bacteriuria; Culture Media; Feces; Humans; Microbial Sensitivity Tests; Micrococcaceae; Penicillanic Acid; Penicillinase; Streptococcus; Urinary Tract Infections

1976
Paradoxical effect of mecillinam on Providencia stuartii.
    The Journal of antimicrobial chemotherapy, 1976, Volume: 2, Issue:4

    Topics: Amdinocillin; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Proteus; Providencia; Urinary Tract Infections

1976
Plasma concentrations and excretion of mecillinam after oral administration of pivmecillinam in elderly patients.
    The Journal of antimicrobial chemotherapy, 1978, Volume: 4, Issue:3

    Topics: Adult; Aged; Amdinocillin; Amdinocillin Pivoxil; Biotransformation; Creatinine; Half-Life; Humans; Kinetics; Penicillanic Acid

1978
Escherichia coli resistance to beta-lactam antibiotics through a decrease in the affinity of a target for lethality.
    Nature, 1978, Aug-17, Volume: 274, Issue:5672

    Topics: Amdinocillin; Carrier Proteins; Cephalosporins; Chromosome Mapping; Escherichia coli; Mutation; Penicillanic Acid; Penicillin Resistance; Penicillins; Temperature

1978
Sensitivity of Yersinia pseudotuberculosis and Yersinia enterocolitica strains to a 6-beta-amidino penicillanic acid derivative.
    The Journal of antimicrobial chemotherapy, 1978, Volume: 4, Issue:4

    Topics: Amdinocillin; Microbial Sensitivity Tests; Penicillanic Acid; Yersinia

1978
Failure of mecillinam and pivmecillinam to eradicate convalescent carriage of salmonellas.
    British medical journal, 1978, Nov-25, Volume: 2, Issue:6150

    Topics: Adult; Aged; Amdinocillin; Amdinocillin Pivoxil; Carrier State; Convalescence; Humans; Middle Aged; Penicillanic Acid; Salmonella Infections

1978
Pivmecillinam (selexid).
    Drug and therapeutics bulletin, 1978, Dec-22, Volume: 16, Issue:26

    Topics: Amdinocillin; Amdinocillin Pivoxil; Enterobacteriaceae Infections; Humans; Penicillanic Acid; Urinary Tract Infections

1978
Mecillinam in urinary tract infections and in septicaemia.
    Infection, 1979, Volume: 7, Issue:1

    Topics: Adult; Aged; Amdinocillin; Anti-Bacterial Agents; Drug Evaluation; Enterobacteriaceae Infections; Escherichia coli Infections; Female; Humans; Injections, Intramuscular; Injections, Intravenous; Male; Middle Aged; Penicillanic Acid; Penicillin Resistance; Sepsis; Urinary Tract Infections

1979
High and selective resistance to mecillinam in adenylate cyclase-deficient or cyclic adenosine 3',5'-monophosphate receptor protein-deficient mutants of Escherichia coli.
    Journal of bacteriology, 1979, Volume: 137, Issue:2

    Topics: Adenylyl Cyclases; Amdinocillin; Cyclic AMP; Escherichia coli; Mutation; Penicillanic Acid; Penicillin Resistance; Receptors, Cyclic AMP

1979
Modification of peptidoglycan structure by penicillin action in cell walls of Proteus mirabilis.
    European journal of biochemistry, 1979, Volume: 95, Issue:3

    Topics: Amdinocillin; Amino Acids; Cell Wall; Macromolecular Substances; Penicillanic Acid; Penicillin G; Peptidoglycan; Protein Binding; Proteus mirabilis; Spheroplasts

1979
[Comparative evaluation of the Enterobacteriaceae sensitivity to 6-(N,N-1', 6-hexyleneformamidino)-penicillanic acid and ampicillin].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1979, May-28, Volume: 34, Issue:22

    Topics: Amdinocillin; Ampicillin; Enterobacteriaceae; Microbial Sensitivity Tests; Penicillanic Acid; Penicillin Resistance

1979
[Effects of ampicillin and cefazolin combined with mecillinam (author's transl)].
    Arzneimittel-Forschung, 1978, Volume: 28, Issue:10

    Topics: Amdinocillin; Ampicillin; Cefazolin; Cross Reactions; Drug Synergism; Escherichia coli; Kinetics; Klebsiella; Penicillanic Acid; Proteus

1978
[Comparison of antibacterial activity of mecillinam against recently isolated bacilli of 5 genera of Enterobacteriaceae from clinical materials with ampicillin, amoxicillin, cephalexin, nalidixic acid and pipemidic acid (author's transl)].
    The Japanese journal of antibiotics, 1979, Volume: 32, Issue:8

    Topics: Amdinocillin; Amoxicillin; Ampicillin; Cephalexin; Enterobacteriaceae; Microbial Sensitivity Tests; Nalidixic Acid; Penicillanic Acid; Penicillin Resistance; Pipemidic Acid

1979
Pharmacokinetics of bacampicillin and bacmecillinam in plasma and peripheral lymph.
    Lymphology, 1979, Volume: 12, Issue:2

    Topics: Adult; Amdinocillin; Ampicillin; Drug Combinations; Drug Synergism; Humans; Lymph; Male; Penicillanic Acid

1979
In vitro combination of mecillinam with cephradine or amoxycillin for organisms resistant to single agents.
    The Journal of antimicrobial chemotherapy, 1979, Volume: 5, Issue:5

    Topics: Amdinocillin; Amoxicillin; Bacteria; Cephalosporins; Cephradine; Drug Synergism; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Penicillin Resistance; Urinary Tract Infections

1979
[Pharmacokinetics of 6/N-1,6' hexylene-formamidyn-penicillanic acid].
    Polskie Archiwum Medycyny Wewnetrznej, 1979, Volume: 62, Issue:4

    Topics: Adult; Amdinocillin; Biotransformation; Half-Life; Humans; Injections, Intramuscular; Injections, Intravenous; Male; Penicillanic Acid

1979
Mecillinam-ampicillin synergism in experimental Enterobacteriaceae meningitis.
    Antimicrobial agents and chemotherapy, 1979, Volume: 16, Issue:3

    Topics: Amdinocillin; Ampicillin; Animals; Drug Synergism; Enterobacteriaceae Infections; Escherichia coli; Klebsiella pneumoniae; Meningitis; Penicillanic Acid; Rabbits

1979
Activity of semisynthetic penicillins and synergism with mecillinam against Bacteroides species.
    Antimicrobial agents and chemotherapy, 1979, Volume: 16, Issue:3

    Topics: Amdinocillin; Bacteroides; Drug Synergism; Microbial Sensitivity Tests; Penicillanic Acid; Penicillins

1979
Effects of subinhibitory amounts of ampicillin, amoxycillin and mecillinam on the adhesion of Escherichia coli bacteria to human urinary tract epithelial cells: a preliminary study.
    Infection, 1979, Volume: 7 Suppl 5

    Topics: Adhesiveness; Amdinocillin; Amoxicillin; Ampicillin; Drug Synergism; Epithelium; Escherichia coli; Humans; In Vitro Techniques; Penicillanic Acid; Urinary Tract

1979
Preliminary experience with parenteral mecillinam.
    Current medical research and opinion, 1979, Volume: 6, Issue:3

    Topics: Adolescent; Adult; Aged; Amdinocillin; Bacterial Infections; Female; Humans; Injections, Intramuscular; Injections, Intravenous; Male; Middle Aged; Penicillanic Acid

1979
Mecillinam and amoxycillin in enteric fever.
    The Journal of antimicrobial chemotherapy, 1979, Volume: 5, Issue:6

    Topics: Adult; Amdinocillin; Amoxicillin; Drug Therapy, Combination; Humans; Middle Aged; Penicillanic Acid; Time Factors; Typhoid Fever

1979
Stability-indicating assay for mecillinam using high-pressure liquid chromatography.
    Journal of chromatography, 1979, Mar-11, Volume: 170, Issue:2

    Topics: Amdinocillin; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Drug Stability; Penicillanic Acid

1979
In-vitro susceptibility of beta-lactamase-producing Haemophilus influenzae to the combinations ampicillin with mecillinam and ampicillin and VD2085.
    The Journal of antimicrobial chemotherapy, 1985, Volume: 16, Issue:6

    Topics: Amdinocillin; Ampicillin; beta-Lactamase Inhibitors; Drug Combinations; Haemophilus influenzae; Microbial Sensitivity Tests; Penicillanic Acid; Pivampicillin

1985
In vitro activity of ampicillin alone and in combination with different concentrations of 6 beta-bromopenicillanic acid, clavulanic acid and mecillinam.
    Scandinavian journal of infectious diseases, 1987, Volume: 19, Issue:1

    Topics: Amdinocillin; Ampicillin; beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Drug Interactions; Drug Synergism; Enterobacteriaceae; Microbial Sensitivity Tests; Penicillanic Acid

1987
Amdinocillin.
    Annals of internal medicine, 1984, Volume: 101, Issue:3

    Topics: Amdinocillin; Bacterial Infections; Enterobacteriaceae; Humans; Penicillanic Acid

1984
Quaternary heterocyclylamino beta-lactams. IV. Comparison of the in vivo antibacterial activities of L-640,876, mecillinam, cefoxitin and cefotaxime.
    The Journal of antibiotics, 1983, Volume: 36, Issue:1

    Topics: Amdinocillin; Animals; Anti-Bacterial Agents; Cefotaxime; Cefoxitin; Cephalosporins; Gram-Negative Bacteria; Kinetics; Mice; Microbial Sensitivity Tests; Penicillanic Acid; Sepsis; Tissue Distribution

1983
Application of the combination radioactivity detector-liquid chromatography to a study of the metabolism of bacmecillinam in the rat.
    Acta pharmaceutica Suecica, 1984, Volume: 21, Issue:2

    Topics: Amdinocillin; Animals; Chromatography, High Pressure Liquid; Humans; Male; Penicillanic Acid; Rats; Rats, Inbred Strains; Sulfur Radioisotopes

1984
Effects of mecillinam and cefoxitin on growth, macromolecular synthesis, and penicillin-binding proteins in a variety of streptococci.
    Antimicrobial agents and chemotherapy, 1983, Volume: 23, Issue:5

    Topics: Amdinocillin; Bacterial Proteins; Carrier Proteins; Cefoxitin; Cell Survival; DNA, Bacterial; Hexosyltransferases; Muramoylpentapeptide Carboxypeptidase; Penicillanic Acid; Penicillin-Binding Proteins; Peptidoglycan; Peptidyl Transferases; RNA, Bacterial; Streptococcus

1983
Cluster of mrdA and mrdB genes responsible for the rod shape and mecillinam sensitivity of Escherichia coli.
    Journal of bacteriology, 1980, Volume: 141, Issue:1

    Topics: Amdinocillin; Chromosome Mapping; Chromosomes, Bacterial; Escherichia coli; Genes; Genetic Linkage; Mutation; Penicillanic Acid; Penicillin Resistance

1980
Control of cell septation by lateral wall extension in a pH-conditional morphology mutant of Klebsiella pneumoniae.
    Journal of bacteriology, 1980, Volume: 142, Issue:1

    Topics: Amdinocillin; Carrier Proteins; Cell Division; Cell Wall; Hydrogen-Ion Concentration; Klebsiella pneumoniae; Mutation; Penicillanic Acid; Penicillins; Peptidoglycan

1980
Determination of mecillinam in urine by reversed-phase high-performance liquid chromatography.
    Journal of chromatography, 1980, Feb-08, Volume: 181, Issue:2

    Topics: Amdinocillin; Chromatography, High Pressure Liquid; Drug Stability; Humans; Penicillanic Acid; Specimen Handling

1980
[Amidinopenicillins (mecillinam and pivmecillinam). A new group of beta-lactamate antibiotics].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1980, Jan-20, Volume: 100, Issue:2

    Topics: Amdinocillin; Amdinocillin Pivoxil; Bacterial Infections; Drug Evaluation; Humans; Penicillanic Acid

1980
[Mecillinam].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1980, Jan-30, Volume: 100, Issue:3

    Topics: Amdinocillin; Humans; Kinetics; Penicillanic Acid

1980
In vitro evaluation of new penicillins and cephalosporins upon P. aeruginosa and their interaction with mecillinam.
    Chemotherapy, 1980, Volume: 26, Issue:4

    Topics: Amdinocillin; Azlocillin; Carbenicillin; Cefamandole; Cefoxitin; Cefsulodin; Cefuroxime; Cephalosporins; Culture Media; Drug Synergism; Mezlocillin; Penicillanic Acid; Penicillins; Pseudomonas aeruginosa; Pyocins; Ticarcillin

1980
The role of beta-lactamase and the outer-membrane structure in the resistance of Enterobacteriaceae to mecillinam.
    Antonie van Leeuwenhoek, 1980, Volume: 46, Issue:1

    Topics: Amdinocillin; beta-Lactamases; Cell Membrane; Escherichia coli; Penicillanic Acid; Penicillin Resistance

1980
In vitro activity of mecillinam and mecillinam/ampicillin combinations on Proteus species.
    The Journal of antimicrobial chemotherapy, 1980, Volume: 6, Issue:3

    Topics: Amdinocillin; Ampicillin; Drug Combinations; Drug Synergism; Microbial Sensitivity Tests; Penicillanic Acid; Penicillin Resistance; Proteus

1980
[Sensitivity to FL 1060 (mecilliman) of E. coli and Klebsiella pneumoniae isolated from bile (author's transl)].
    The Japanese journal of antibiotics, 1980, Volume: 33, Issue:3

    Topics: Amdinocillin; Amoxicillin; Ampicillin; Bile; Cephalexin; Escherichia coli; Humans; Klebsiella pneumoniae; Penicillanic Acid; Penicillin Resistance

1980
In vitro activity of mecillinam against anaerobic bacteria.
    Antimicrobial agents and chemotherapy, 1980, Volume: 17, Issue:6

    Topics: Amdinocillin; Anaerobiosis; Bacteria; Culture Media; Half-Life; Humans; Intestinal Absorption; Microbial Sensitivity Tests; Penicillanic Acid

1980
Mecillinam in patients on haemodialysis.
    British journal of clinical pharmacology, 1980, Volume: 10, Issue:2

    Topics: Adult; Aged; Amdinocillin; Humans; Middle Aged; Penicillanic Acid; Renal Dialysis

1980
Mecillinam and enteric fever.
    The Journal of antimicrobial chemotherapy, 1980, Volume: 6, Issue:4

    Topics: Amdinocillin; Humans; Penicillanic Acid; Typhoid Fever

1980
Sensitivities of clinically significant organisms to four cephalosporins, ampicillin and mecillinam.
    Current medical research and opinion, 1980, Volume: 7, Issue:2

    Topics: Amdinocillin; Ampicillin; Bacterial Infections; Cefamandole; Cefoxitin; Cefuroxime; Cephalexin; Cephalosporins; Humans; Microbial Sensitivity Tests; Penicillanic Acid

1980
Effect of beta-lactamase and salt on mecillinam susceptibility of enterobacterial strains.
    Antimicrobial agents and chemotherapy, 1980, Volume: 18, Issue:5

    Topics: Amdinocillin; Anti-Bacterial Agents; beta-Lactamases; Cell-Free System; Conjugation, Genetic; Enterobacteriaceae; Microbial Sensitivity Tests; Penicillanic Acid; Sodium Chloride

1980
Antibiotic sensitivity of enteropathogenic Escherichia coli to mecillinam, trimethoprim-sulfamethoxazole and other antibiotics.
    Acta pathologica et microbiologica Scandinavica. Section B, Microbiology, 1980, Volume: 88, Issue:5

    Topics: Amdinocillin; Anti-Bacterial Agents; Diarrhea; Escherichia coli; Microbial Sensitivity Tests; Penicillanic Acid; Penicillin Resistance; Serotyping; Sulfamethoxazole; Trimethoprim

1980
Appraisal of disk sensitivity tests with mecillinam.
    Chemotherapy, 1981, Volume: 27, Issue:2

    Topics: Amdinocillin; Enterobacteriaceae; Microbial Sensitivity Tests; Penicillanic Acid

1981
Effect of urine concentration versus tissue concentration of ampicillin and mecillinam on bacterial adherence in the rat bladder.
    Investigative urology, 1981, Volume: 18, Issue:5

    Topics: Amdinocillin; Ampicillin; Animals; Escherichia coli; Female; Injections; Male; Penicillanic Acid; Rats; Urinary Bladder; Urinary Tract Infections

1981
An evaluation of parenteral mecillinam in a chest hospital.
    Current medical research and opinion, 1981, Volume: 7, Issue:3

    Topics: Adult; Aged; Amdinocillin; Amoxicillin; Female; Hospitals; Humans; Male; Middle Aged; Penicillanic Acid; Respiratory Tract Infections; Urinary Tract Infections

1981
Mecillinam resistance in Escherichia coli: dissociation of growth inhibition and morphologic change.
    The Journal of infectious diseases, 1981, Volume: 143, Issue:1

    Topics: Adult; Amdinocillin; Anti-Bacterial Agents; Escherichia coli; Escherichia coli Infections; Humans; Male; Mutation; Penicillanic Acid; Penicillin Resistance; Phenotype; Sepsis

1981
Activity of mecillinam alone and in combination with other beta-lactam antibiotics.
    Antimicrobial agents and chemotherapy, 1980, Volume: 18, Issue:6

    Topics: Amdinocillin; Anti-Bacterial Agents; Bacteria; Drug Synergism; Enterobacteriaceae; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa

1980
Pharmacokinetics of mecillinam in health subjects.
    Antimicrobial agents and chemotherapy, 1980, Volume: 18, Issue:6

    Topics: Adult; Amdinocillin; Female; Half-Life; Humans; Kinetics; Male; Metabolic Clearance Rate; Penicillanic Acid

1980
Filament formation of Fusobacterium nucleatum cells induced by mecillinam.
    Antimicrobial agents and chemotherapy, 1981, Volume: 19, Issue:3

    Topics: Amdinocillin; Bacterial Proteins; Carrier Proteins; Fusobacterium; Hexosyltransferases; Microbial Sensitivity Tests; Muramoylpentapeptide Carboxypeptidase; Penicillanic Acid; Penicillin-Binding Proteins; Peptidyl Transferases

1981
Mecillinam susceptibility of Escherichia coli K-12 mutants deficient in the adenosine 3',5'-monophosphate system.
    Antimicrobial agents and chemotherapy, 1981, Volume: 19, Issue:4

    Topics: Amdinocillin; Cyclic AMP; Escherichia coli; Microbial Sensitivity Tests; Mutation; Penicillanic Acid; Penicillin Resistance; Time Factors

1981
The X-ray structural investigation of 6-(n,n-1,6-hexyleneformamidine)-penicillanic acid (mecillinam).
    The Journal of antibiotics, 1981, Volume: 34, Issue:3

    Topics: Amdinocillin; Crystallography; Molecular Conformation; Penicillanic Acid; X-Ray Diffraction

1981
Effect of combination of cefsulodin and mecillinam.
    The Journal of antibiotics, 1981, Volume: 34, Issue:6

    Topics: Amdinocillin; Animals; Bacteria; Bacterial Infections; Cefsulodin; Cephalosporins; Drug Synergism; Drug Therapy, Combination; Male; Mice; Penicillanic Acid; Serratia marcescens; Species Specificity

1981
Synergistic effect of cephalexin with mecillinam.
    The Journal of antibiotics, 1981, Volume: 34, Issue:6

    Topics: Amdinocillin; Animals; Bacteria; Bacterial Infections; Cephalexin; Drug Synergism; Drug Therapy, Combination; Escherichia coli; Male; Mice; Penicillanic Acid; Species Specificity

1981
Plasmid-mediated partial cross-resistance between ampicillin, mecillinam and cefamandole in Salmonella johannesburg and Salmonella typhimurium.
    The Journal of antimicrobial chemotherapy, 1981, Volume: 7, Issue:3

    Topics: Amdinocillin; Ampicillin; Cefamandole; Cephalosporins; Penicillanic Acid; Penicillin Resistance; Plasmids; Salmonella; Salmonella typhimurium

1981
Comparative activity of mecillinam and ampicillin singly and in combination in the urinary bladder model and experimental mouse model.
    The Journal of antimicrobial chemotherapy, 1981, Volume: 8, Issue:2

    Topics: Amdinocillin; Ampicillin; Animals; beta-Lactamases; Disease Models, Animal; Drug Combinations; Enterobacteriaceae; Humans; Mice; Microbial Sensitivity Tests; Penicillanic Acid; Urinary Bladder; Urinary Tract Infections

1981
Penicillanic acid derivatives in the canine prostate.
    The Prostate, 1980, Volume: 1, Issue:1

    Topics: Amdinocillin; Amdinocillin Pivoxil; Amoxicillin; Ampicillin; Animals; Carbenicillin; Dogs; Male; Penicillanic Acid; Prostate

1980
Early initiation of deoxyribonucleic acid replication and shortening of generation time associated with inhibition of lateral wall formation by mecillinam.
    Journal of bacteriology, 1981, Volume: 148, Issue:1

    Topics: Amdinocillin; Bacterial Proteins; Cell Division; Cell Wall; DNA, Bacterial; Kinetics; Klebsiella pneumoniae; Nalidixic Acid; Penicillanic Acid

1981
Effect of subinhibitory concentrations of mecillinam on the serum susceptibility of Escherichia coli strains.
    Antimicrobial agents and chemotherapy, 1981, Volume: 19, Issue:5

    Topics: Amdinocillin; Amdinocillin Pivoxil; Blood Bactericidal Activity; Escherichia coli; Humans; Infant, Newborn; Infant, Newborn, Diseases; Meningitis; Penicillanic Acid; Urinary Tract Infections

1981
Susceptibility to mecillinam and other antibiotics of 28 O-serotypes of Yersinia enterocolitica.
    The Journal of antimicrobial chemotherapy, 1981, Volume: 8, Issue:4

    Topics: Amdinocillin; Ampicillin; Anti-Bacterial Agents; Carbenicillin; Humans; Penicillanic Acid; Penicillin Resistance; Serotyping; Yersinia

1981
[Antibacterial activity of mecillinam against E. coli isolated from urinary tract infections (author's transl)].
    The Japanese journal of antibiotics, 1981, Volume: 34, Issue:7

    Topics: Amdinocillin; Escherichia coli; Humans; Penicillanic Acid; Penicillin Resistance; Urinary Tract Infections

1981
[Treatment of urinary tract infections with penicillin Hx].
    Polskie Archiwum Medycyny Wewnetrznej, 1981, Volume: 66, Issue:2

    Topics: Adult; Aged; Amdinocillin; Bacteria; Bacteriuria; Drug Evaluation; Female; Humans; Male; Middle Aged; Penicillanic Acid; Penicillin Resistance

1981
Determination of amdinocillin in plasma and urine by high-performance liquid chromatography.
    Journal of chromatography, 1982, Jan-08, Volume: 227, Issue:1

    Topics: Amdinocillin; Chromatography, High Pressure Liquid; Humans; Injections, Intravenous; Microbiological Techniques; Penicillanic Acid; Reference Values

1982
[Synthetic penicillins. Properties of new amidinopenicillins and their acetylmethyl esters].
    Acta poloniae pharmaceutica, 1981, Volume: 38, Issue:4

    Topics: Amdinocillin; Animals; Bacteria; Biological Availability; Chemical Phenomena; Chemistry; Drug Evaluation, Preclinical; Esters; In Vitro Techniques; Microbial Sensitivity Tests; Penicillanic Acid; Rats

1981
Inhibitory activity and bactericidal kinetics of mecillinam/ampicillin combinations against Enterobacteriaceae, Pseudomonas and Acinetobacter.
    Infection, 1981, Volume: 9, Issue:6

    Topics: Acinetobacter; Amdinocillin; Ampicillin; Drug Combinations; Drug Synergism; Enterobacteriaceae; Penicillanic Acid; Pseudomonas

1981
Interaction between non-classical beta-lactam compounds and the Zn2+-containing G and serine R61 and R39 D-alanyl-D-alanine peptidases.
    The Biochemical journal, 1981, Oct-01, Volume: 199, Issue:1

    Topics: Actinomycetaceae; Amdinocillin; beta-Lactams; Carboxypeptidases; Cefoxitin; Cephalosporins; Clavulanic Acid; Drug Interactions; Endopeptidases; Enzyme Inhibitors; Imipenem; Kinetics; Penicillanic Acid; Penicillins; Quinoxalines; Serine-Type D-Ala-D-Ala Carboxypeptidase; Streptomyces; Zinc

1981
[Clinical evaluation of intravenous mecillinam in patients with chronic urinary infection and reduced renal function].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1981, Oct-10, Volume: 101, Issue:28

    Topics: Adult; Aged; Amdinocillin; Female; Humans; Injections, Intravenous; Kidney; Male; Middle Aged; Penicillanic Acid; Uremia; Urinary Tract Infections

1981
Induction of cell lysis in Escherichia coli: cooperative effect of nocardicin A and mecillinam.
    Antimicrobial agents and chemotherapy, 1982, Volume: 21, Issue:2

    Topics: Amdinocillin; Anti-Bacterial Agents; Carrier Proteins; Drug Interactions; Drug Synergism; Escherichia coli; Lactams; Penicillanic Acid; Penicillins

1982
A study of the biliary excretion of mecillinam in patients with biliary disease.
    The Journal of antimicrobial chemotherapy, 1982, Volume: 9, Issue:3

    Topics: Amdinocillin; Bile; Biliary Tract Diseases; Cholecystitis; Cholestasis; Humans; Penicillanic Acid

1982
In vitro activity of moxalactam and mecillinam, singly and in combination, against multi-drug-resistant Enterobacteriaceae and Pseudomonas species.
    Antimicrobial agents and chemotherapy, 1982, Volume: 21, Issue:1

    Topics: Amdinocillin; Anti-Bacterial Agents; Cephalosporins; Cephamycins; Drug Interactions; Enterobacteriaceae; Microbial Sensitivity Tests; Moxalactam; Penicillanic Acid; Penicillin Resistance; Pseudomonas

1982
Multiple-dose pharmacokinetics of amdinocillin in healthy volunteers.
    Antimicrobial agents and chemotherapy, 1982, Volume: 21, Issue:1

    Topics: Adult; Amdinocillin; Anti-Bacterial Agents; Female; Humans; Kinetics; Male; Middle Aged; Penicillanic Acid

1982
Mecillinam alone and in combination with ampicillin or moxalactam in experimental Escherichia coli meningitis.
    Infection, 1982, Volume: 10, Issue:2

    Topics: Amdinocillin; Ampicillin; Animals; Cephalosporins; Cephamycins; Drug Synergism; Drug Therapy, Combination; Escherichia coli; Escherichia coli Infections; Female; Kinetics; Male; Meningitis; Mice; Moxalactam; Penicillanic Acid; Rabbits

1982
Virulence of mecillinam-resistant spherical mutants of Klebsiella pneumoniae and Escherichia coli.
    The Journal of antimicrobial chemotherapy, 1982, Volume: 9, Issue:5

    Topics: Amdinocillin; Animals; Escherichia coli; Humans; In Vitro Techniques; Klebsiella pneumoniae; Lethal Dose 50; Mice; Neutrophils; Penicillanic Acid; Penicillin Resistance; Phagocytosis

1982
Susceptibility of shigellae to mecillinam, nalidixic acid, trimethoprim, and five other antimicrobial agents.
    Antimicrobial agents and chemotherapy, 1981, Volume: 19, Issue:2

    Topics: Amdinocillin; Anti-Bacterial Agents; Microbial Sensitivity Tests; Nalidixic Acid; Penicillanic Acid; Penicillin Resistance; Shigella; Trimethoprim

1981
Treatment of experimental Salmonella typhimurium infection with mecillinam and ampicillin.
    Antimicrobial agents and chemotherapy, 1981, Volume: 19, Issue:2

    Topics: Amdinocillin; Ampicillin; Animals; Female; Mice; Microbial Sensitivity Tests; Penicillanic Acid; Salmonella Infections, Animal; Salmonella typhimurium; Spleen

1981
Synergistic activity of mecillinam in combination with the beta-lactamase inhibitors clavulanic acid and sulbactam.
    Antimicrobial agents and chemotherapy, 1982, Volume: 22, Issue:3

    Topics: Amdinocillin; Bacteria; beta-Lactamase Inhibitors; Clavulanic Acids; Drug Synergism; Penicillanic Acid; Sulbactam

1982
Determination of bacmecillinam, an amdinocillin prodrug, in human and canine whole blood by reversed-phase liquid chromatography.
    Journal of pharmaceutical sciences, 1982, Volume: 71, Issue:10

    Topics: Amdinocillin; Animals; Bile; Chromatography, High Pressure Liquid; Dogs; Drug Stability; Humans; Hydrogen-Ion Concentration; Male; Penicillanic Acid; Species Specificity; Spectrophotometry, Ultraviolet

1982
[Sensitivity of Enterobacteriaceae isolated from humans to 6-N,N-1',6'-hexyleneformamidine-penicillanic acid (preparation HX)].
    Medycyna doswiadczalna i mikrobiologia, 1982, Volume: 34, Issue:1-2

    Topics: Amdinocillin; Ampicillin; Drug Resistance; Enterobacter; Enterobacteriaceae; Escherichia coli; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests; Penicillanic Acid; Penicillin Resistance; Proteus; Salmonella; Shigella

1982
[Combined effect of 6/N,N-1',6'-hexyleneformamidine-penicillanic acid (preparation HX) and selected beta-lactam antibiotics on E. coli and Salmonella. I. Studies in vitro].
    Medycyna doswiadczalna i mikrobiologia, 1982, Volume: 34, Issue:1-2

    Topics: Amdinocillin; Anti-Bacterial Agents; Drug Synergism; Escherichia coli; Microbial Sensitivity Tests; Penicillanic Acid; Penicillin Resistance; Salmonella

1982
[Microbiological evaluation of the results of penicillin Hx treatment of urinary tract infection].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1982, Jul-05, Volume: 37, Issue:21

    Topics: Amdinocillin; Bacterial Infections; Bacteriuria; Candida; Candidiasis; Enterobacteriaceae; Female; Humans; Male; Micrococcus; Penicillanic Acid; Pseudomonas; Staphylococcus aureus; Streptococcus agalactiae

1982
Murein and lipopolysaccharide biosynthesis in synchronized cells of Escherichia coli K 12 and the effect of penicillin G, mecillinam and nalidixic acid.
    Archives of microbiology, 1982, Volume: 132, Issue:3

    Topics: Amdinocillin; Cell Division; Escherichia coli; Lipopolysaccharides; Nalidixic Acid; Penicillanic Acid; Penicillin G; Peptidoglycan

1982
Effect of protein synthesis inhibition on the induction of cell lysis in Escherichia coli by mecillinam plus nocardicin A.
    Antimicrobial agents and chemotherapy, 1982, Volume: 22, Issue:6

    Topics: Amdinocillin; Anti-Bacterial Agents; Bacterial Proteins; Chloramphenicol; Escherichia coli; Lactams; Penicillanic Acid; Time Factors

1982
A mecillinam-sensitive peptidoglycan crosslinking reaction in Escherichia coli.
    Biochemical and biophysical research communications, 1982, Dec-15, Volume: 109, Issue:3

    Topics: Amdinocillin; Bacterial Proteins; Carrier Proteins; Cell Membrane; Cross-Linking Reagents; Escherichia coli; Hexosyltransferases; Kinetics; Muramoylpentapeptide Carboxypeptidase; Penicillanic Acid; Penicillin-Binding Proteins; Peptidoglycan; Peptidyl Transferases

1982
[Studies on the combined effect of 6/N,N-hexyleneformamidine/-penicillanic acid (Preparation HX) and selected beta-lactam antibiotics on Escherichia coli and Salmonella. II. Studies in vivo].
    Medycyna doswiadczalna i mikrobiologia, 1982, Volume: 34, Issue:3-4

    Topics: Amdinocillin; Animals; Anti-Bacterial Agents; Cefazolin; Cephalosporins; Cephradine; Drug Synergism; Escherichia coli Infections; Mice; Mice, Inbred BALB C; Penicillanic Acid; Salmonella Infections

1982
Pivmecillinam in treatment of Staphylococcus saprophyticus urinary tract infections.
    Scandinavian journal of infectious diseases, 1983, Volume: 15, Issue:1

    Topics: Age Factors; Aged; Amdinocillin; Amdinocillin Pivoxil; Child; Child, Preschool; Escherichia coli; Female; Follow-Up Studies; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Penicillin Resistance; Seasons; Sex Factors; Staphylococcal Infections; Staphylococcus; Sweden; Urinary Tract Infections

1983
The antibacterial activity of combinations of mecillinam and ampicillin in vitro and in normal and granulopenic mice.
    Scandinavian journal of infectious diseases, 1983, Volume: 15, Issue:1

    Topics: Amdinocillin; Ampicillin; Animals; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Escherichia coli; Granulocytes; Leukopenia; Male; Mice; Penicillanic Acid

1983
Comparison of in vitro and in vivo ampicillin susceptibility of Escherichia coli pretreated with low concentrations of mecillinam and ampicillin.
    Scandinavian journal of infectious diseases, 1983, Volume: 15, Issue:1

    Topics: Amdinocillin; Ampicillin; Animals; Colony-Forming Units Assay; Disease Models, Animal; Drug Synergism; Escherichia coli; Granulocytes; Leukopenia; Male; Mice; Microbial Sensitivity Tests; Penicillanic Acid

1983
[Treatment of selected bacterial infections with "Polfa" penicillin Hx].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1982, Dec-20, Volume: 37, Issue:50

    Topics: Adolescent; Adult; Aged; Amdinocillin; Enterobacteriaceae; Enterobacteriaceae Infections; Female; Humans; Male; Middle Aged; Penicillanic Acid; Penicillin Resistance; Penicillins; Pseudomonas aeruginosa; Pseudomonas Infections; Staphylococcal Infections; Staphylococcus aureus

1982
Comparison of in vitro activity of mecillinam with other antimicrobial chemotherapeutic agents against Salmonella Shigella and El Tor Vibrio cholerae.
    East African medical journal, 1982, Volume: 59, Issue:10

    Topics: Amdinocillin; Ampicillin; Anti-Bacterial Agents; In Vitro Techniques; Microbial Sensitivity Tests; Penicillanic Acid; Penicillin Resistance; Salmonella; Shigella; Vibrio cholerae

1982
An international review of amdinocillin: a new beta-lactam antibiotic.
    The American journal of medicine, 1983, Aug-29, Volume: 75, Issue:2A

    Topics: Amdinocillin; Animals; Humans; Penicillanic Acid

1983
Amdinocillin: use alone or in combination with cefoxitin or carbenicillin-ticarcillin.
    The American journal of medicine, 1983, Aug-29, Volume: 75, Issue:2A

    Topics: Acute Disease; Adolescent; Adult; Aged; Amdinocillin; Bacterial Infections; Carbenicillin; Cefoxitin; Drug Therapy, Combination; Female; Humans; Leukemia; Leukocyte Count; Male; Middle Aged; Neutrophils; Penicillanic Acid; Penicillins; Sepsis; Ticarcillin

1983
Efficacy, pharmacology, and safety of amdinocillin in treatment of neonates.
    The American journal of medicine, 1983, Aug-29, Volume: 75, Issue:2A

    Topics: Amdinocillin; Bacterial Infections; Drug Therapy, Combination; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Injections, Intramuscular; Kinetics; Male; Penicillanic Acid; Penicillins

1983
Management of enteric fever with amdinocillin.
    The American journal of medicine, 1983, Aug-29, Volume: 75, Issue:2A

    Topics: Adolescent; Adult; Amdinocillin; Amdinocillin Pivoxil; Ampicillin; Body Temperature; Child; Drug Combinations; Feces; Female; Humans; Male; Penicillanic Acid; Recurrence; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Typhoid Fever

1983
Enhanced activity of beta-lactam antibiotics with amdinocillin in vitro and and in vivo.
    The American journal of medicine, 1983, Aug-29, Volume: 75, Issue:2A

    Topics: Amdinocillin; Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Drug Synergism; Drug Therapy, Combination; Mice; Microbial Sensitivity Tests; Penicillanic Acid

1983
Morphologic changes produced by amdinocillin alone and in combination with beta-lactam antibiotics: in vitro and in vivo.
    The American journal of medicine, 1983, Aug-29, Volume: 75, Issue:2A

    Topics: Amdinocillin; Animals; Anti-Bacterial Agents; Bacteria; Drug Synergism; Escherichia coli; Escherichia coli Infections; Klebsiella pneumoniae; Mice; Microscopy, Electron, Scanning; Penicillanic Acid

1983
Study of the enhancement of beta-lactam activity by amdinocillin in a model of the human urinary bladder.
    The American journal of medicine, 1983, Aug-29, Volume: 75, Issue:2A

    Topics: Amdinocillin; Ampicillin; Anti-Bacterial Agents; Drug Synergism; Enterobacteriaceae; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Urinary Bladder; Urine

1983
Amdinocillin pharmacokinetics. Simultaneous administration with cephalothin and cerebrospinal fluid penetration.
    The American journal of medicine, 1983, Aug-29, Volume: 75, Issue:2A

    Topics: Adult; Aged; Amdinocillin; Cephalothin; Drug Interactions; Female; Half-Life; Humans; Kinetics; Male; Metabolic Clearance Rate; Middle Aged; Models, Biological; Penicillanic Acid

1983
Pharmacokinetics of amdinocillin and pivamdinocillin in normal volunteers.
    The American journal of medicine, 1983, Aug-29, Volume: 75, Issue:2A

    Topics: Administration, Oral; Adult; Amdinocillin; Amdinocillin Pivoxil; Biological Availability; Humans; Infusions, Parenteral; Kinetics; Metabolic Clearance Rate; Models, Biological; Penicillanic Acid

1983
Levels of amdinocillin in human plasma and interstitial fluid following intravenous administration.
    The American journal of medicine, 1983, Aug-29, Volume: 75, Issue:2A

    Topics: Adult; Amdinocillin; Extracellular Space; Humans; Infusions, Parenteral; Male; Penicillanic Acid; Skin

1983
Parenteral amdinocillin for treatment of complicated urinary tract infections.
    The American journal of medicine, 1983, Aug-29, Volume: 75, Issue:2A

    Topics: Adolescent; Adult; Aged; Amdinocillin; Enterobacteriaceae Infections; Female; Humans; Infusions, Parenteral; Injections, Intramuscular; Male; Middle Aged; Penicillanic Acid; Postoperative Complications; Urinary Tract Infections

1983
Combination amdinocillin and cefoxitin therapy of multiply-resistant Serratia marcescens urinary tract infections.
    The American journal of medicine, 1983, Aug-29, Volume: 75, Issue:2A

    Topics: Adult; Aged; Amdinocillin; Cefoxitin; Drug Therapy, Combination; Enterobacteriaceae Infections; Humans; Injections, Intravenous; Male; Middle Aged; Penicillanic Acid; Serratia marcescens; Urinary Tract Infections

1983
Systemic infections treated with amdinocillin in combination with other beta-lactam antibiotics.
    The American journal of medicine, 1983, Aug-29, Volume: 75, Issue:2A

    Topics: Amdinocillin; Anti-Bacterial Agents; Bacterial Infections; Drug Synergism; Drug Therapy, Combination; Female; Humans; Male; Penicillanic Acid; Urinary Tract Infections

1983
Amdinocillin in combination with beta-lactam antibiotics for treatment of serious gram-negative infections.
    The American journal of medicine, 1983, Aug-29, Volume: 75, Issue:2A

    Topics: Adolescent; Adult; Aged; Amdinocillin; Anti-Bacterial Agents; Drug Synergism; Drug Therapy, Combination; Escherichia coli Infections; Female; Humans; Injections, Intravenous; Klebsiella Infections; Klebsiella pneumoniae; Male; Middle Aged; Penicillanic Acid

1983
Pharmacokinetics of amdinocillin in healthy adults.
    Antimicrobial agents and chemotherapy, 1983, Volume: 23, Issue:6

    Topics: Adult; Aged; Amdinocillin; Female; Humans; Infusions, Parenteral; Injections, Intramuscular; Kinetics; Male; Middle Aged; Penicillanic Acid

1983
[Penicillin Hx "Polfa" concentration in body fluids in adults after intramuscular administration].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1983, Mar-14, Volume: 38, Issue:11

    Topics: Adolescent; Adult; Amdinocillin; Bile; Biological Availability; Cerebrospinal Fluid; Drug Evaluation; Female; Humans; Injections, Intramuscular; Male; Middle Aged; Penicillanic Acid; Penicillins; Time Factors

1983
[Combined antimicrobial action of mecillinam and ampicillin].
    Antibiotiki, 1983, Volume: 28, Issue:8

    Topics: Amdinocillin; Ampicillin; Bacteria; Drug Synergism; Kinetics; Microbial Sensitivity Tests; Penicillanic Acid

1983
Inhibition of lateral wall elongation by mecillinam stimulates cell division in certain cell division conditional mutants of Escherichia coli.
    Journal of bacteriology, 1984, Volume: 157, Issue:1

    Topics: Amdinocillin; Cell Division; Cell Wall; Escherichia coli; Mutation; Penicillanic Acid; Penicillin Resistance; Temperature

1984
Susceptibility to mecillinam and other antibiotics and serogroups of enterotoxigenic Escherichia coli from children in Addis Ababa.
    The Journal of antimicrobial chemotherapy, 1983, Volume: 12, Issue:5

    Topics: Amdinocillin; Anti-Bacterial Agents; Child; Child, Preschool; Enterotoxins; Escherichia coli; Ethiopia; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Penicillanic Acid

1983
[Comparative studies on the sensitivity of Enterobacteriaceae strains to penicillin HX].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1983, Nov-14, Volume: 38, Issue:46

    Topics: Amdinocillin; Enterobacteriaceae; In Vitro Techniques; Microbial Sensitivity Tests; Penicillanic Acid; Penicillin Resistance

1983
[Inhibitory activity of ampicillin and mecillinam on Haemophilus influenzae].
    Pathologie-biologie, 1984, Volume: 32, Issue:5

    Topics: Amdinocillin; Ampicillin; Haemophilus influenzae; Penicillanic Acid

1984
In vitro interaction between mecillinam and piperacillin-tazobactam in the presence of azithromycin against members of the Enterobacteriaceae family and Pseudomonas aeruginosa.
    The new microbiologica, 2008, Volume: 31, Issue:1

    Topics: Amdinocillin; Anti-Bacterial Agents; Azithromycin; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Enterobacteriaceae; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa

2008