penicillamine and tiopronin

penicillamine has been researched along with tiopronin in 73 studies

Research

Studies (73)

Timeframe	Studies, this research(%)	All Research%
pre-1990	32 (43.84)	18.7374
1990's	21 (28.77)	18.2507
2000's	11 (15.07)	29.6817
2010's	7 (9.59)	24.3611
2020's	2 (2.74)	2.80

Authors

Authors	Studies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Brimacombe, KR; Dulcey, AE; Goldsborough, AS; Gottesman, MM; Griffiths, G; Hall, MD; Handley, MD; Kannan, P; Pluchino, KM	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Basile, G; Ginevri, F; Gusmano, R; Perfumo, F	1
Stuhlsatz, HW; Terhorst, B	1
Graf, U; Müller, W; Rosenthal, M	1
Hautmann, R; Lutzeyer, W; Stuhlsatz, HW; Terhorst, B	1
de Angelis, E; Grassi, M; Lombardi, ML; Ruocco, V	1
Gayraud, M; Guillevin, L	1
Chicault, P; Ehrhart, A; Fauquert, P; Le Goff, P	1
Combe, B; Daures, JP; Sany, J; Tagemouati, A; Verdie-Petibon, D	1
de Angelis, E; Lombardi, ML; Pisani, M; Ruocco, V	1
Denneberg, T; Lindell, A; Mårtensson, J; Textorius, O	1
Jaeger, P	1
Crossley, MJ; Hunneyball, IM; Spowage, M	1
Jaffe, IA	1
Cuperus, RA; Muijsers, AO; Wever, R	1
Imamura, S; Miyachi, Y; Niwa, Y; Yoshioka, A	1
Bennett, A; Capasso, F; Tavares, IA; Tsang, R	1
Maisonneuve, H; Maugars, Y; Prost, A; Sigaud, M	1
Kuck, JF; Kuck, KD	1
Amor, B; de Gery, A; Mery, C	1
Adams, BV; Fuller, C; Pak, CY; Sakhaee, K; Zerwekh, JE	1
Pahira, JJ	1
Bourgeois, P; Brion, N; Elleuch, M; Kahn, MF	1
Amor, B; de Gery, A; Mery, C; Zizi, M	1
Cusworth, DC; Harbar, JA; Lawes, LC; Wrong, OM	1
Cavrini, V; Di Pietra, AM; Nobile, L; Raggi, MA	1
Dal Forno, S; De Dominicis, C; Franco, G; Gallucci, M; Iori, F; Laurenti, C	1
Refsvik, T	2
Denneberg, T; Jeppsson, JO; Stenberg, P	1
Mansell, MA	1
Asper, R; Schmucki, O	1
Ambanelli, U; Barbieri, P; Ciompi, ML; Colamussi, V; Ferraccioli, G; Mazzoni, MR; Menegale, G; Pasero, G; Pellegrini, P; Trippi, D	1
Bruno, M; Fruttero, B; Linari, F; Marangella, M	1
Cavrini, V; Di Pietra, AM; Raggi, MA	1
Matthes, KJ	1
Capasso, F	1
Bergevin, H; Camus, JP; Cassou, B; Prier, A	1
Barbieri, P; Ciompi, ML; Colamussi, V; Mazzoni, MR; Pasero, G; Pellegrini, P	1
Persu, A; Pirson, Y	1
Beyersbergen van Henegouwen, GM; van den Broeke, LT	1
Brin, S; Combe, B; Delecoeuillerie, G; Paolozzi, L; Sany, J	1
Albero, MI; Garcia, MS; Rodenas, V; Sanchez-Pedreño, C	1
de Angelis, E; Lombardi, ML; Rossano, F; Ruocco, V	1
Lopez Garcia, I; Martinez Gil, JA; Viñas, P	1
Denneberg, T; Frank, A; Hoppe, A; Kågedals, B; Petersson, LR	1
Hoener, B; Shen, W	1
Chow, GK; Streem, SB	1
Martínez-Lozano, C; Pérez Ruiz, T; Sidrach de Cardona, C; Tomás, V	1
Deltas, CC; Pierides, AM	1
Horie, T; Matsukawa, Y; Nishinarita, S; Ryu, J; Saito, N	1
Asanuma, H; Kawamura, T; Nagakura, K; Nakai, H; Shishido, S; Takeda, M; Yamafuji, M	1
Akakura, K; Egoshi, K; Ito, H; Kotake, T; Masai, M; Nozumi, K; Ueda, T	1
Coe, FL; Nakagawa, Y	1
Aono, H; Horiuchi, M; Matsuoka, H; Mita, S; Nishimura, K; Takai, M; Tsuji, F	1
Asplin, JR; Clark, C; Coe, FL; Parks, JH	1
Christensson, A; Denneberg, T; Fjellstedt, E; Jeppsson, JO; Tiselius, HG	1
Despaux, J; Lehuédé, G; Michel, F; Toussirot, E; Wendling, D	1
Alken, P; Janitzky, V; Knoll, T; Köhrmann, KU; Michel, MS	1
Denneberg, T; Fjellstedt, E; Harnevik, L; Jeppsson, JO; Söderkvist, P; Tiselius, HG	1
Dziarmaga, A; Goodyer, P; Parvex, P; Rozen, R	1
Asplin, JR; Dolin, DJ; Flagel, L; Goldfarb, DS; Grasso, M	1
Bald, E; Kuśmierek, K	1
Dello Strologo, L; Laurenzi, C; Legato, A; Pastore, A	1
Sajewicz, W	1
Cracco, CM; Scoffone, CM	1
Bataille, P; Bridoux, F; Brignon, P; Choquenet, C; Cochat, P; Combe, C; Conort, P; Courbebaisse, M; Daudon, M; Decramer, S; Doré, B; Dussol, B; Essig, M; Friedlander, G; Frimat, M; Gaunez, N; Jais, JP; Joly, D; Knebelmann, B; Le Toquin-Bernard, S; Lebbah, S; Lillo-Le Louët, A; Méjean, A; Meria, P; Morin, D; N'Guyen, HV; Normand, M; Pietak, M; Pontoizeau, C; Prot-Bertoye, C; Ronco, P; Saussine, C; Tostivint, I; Traxer, O; Tsimaratos, M	1
Asplin, JR; Enders, FT; Goldfarb, DS; Malieckal, DA; Mara, K; Modersitzki, F	1
Henderickx, MM; Homan van der Heide, JJ; Kamphuis, GM; Melessen, IM; Merkx, MM; van Etten-Jamaludin, FS	1
Courbebaisse, M; Daudon, M; Defazio, J; Dousseaux, MP; Knebelmann, B; Prot-Bertoye, C; Tostivint, I; Traxer, O	1

Reviews

11 review(s) available for penicillamine and tiopronin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[The hyperaminoacidurias with special reference to cystinuria]. Minerva medica, 1979, Oct-13, Volume: 70, Issue:44 Topics: Amino Acids; Biological Transport; Carrier Proteins; Child; Cystinuria; Female; Humans; Microvilli; Penicillamine; Renal Tubular Transport, Inborn Errors; Tiopronin; Urinary Calculi	1979
[Pleuropulmonary manifestations of rheumatoid arthritis]. Annales de medecine interne, 1990, Volume: 141, Issue:5 Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Bronchial Diseases; Bronchoalveolar Lavage Fluid; Cyclophosphamide; Humans; Lung Diseases; Methotrexate; Organogold Compounds; Penicillamine; Pleural Diseases; Respiratory Tract Diseases; Tiopronin	1990
Cystinuria: pathophysiology and treatment. Advances in nephrology from the Necker Hospital, 1989, Volume: 18 Topics: Captopril; Cystinuria; Humans; Penicillamine; Tiopronin	1989
Adverse effects profile of sulfhydryl compounds in man. The American journal of medicine, 1986, Volume: 80, Issue:3 Topics: Anemia, Aplastic; Autoimmune Diseases; Captopril; Drug Eruptions; Glomerulonephritis; Humans; Neutropenia; Penicillamine; Pyridoxine; Pyrithioxin; Stomatitis; Sulfhydryl Compounds; Taste; Thrombocytopenia; Tiopronin	1986
[Current aspects of the medical treatment of cystinuria]. Acta urologica Belgica, 1994, Volume: 62, Issue:2 Topics: Ascorbic Acid; Captopril; Cystine; Cystinuria; Humans; Hydrogen-Ion Concentration; Penicillamine; Solubility; Tiopronin; Urine	1994
Yellow nail syndrome associated with thiol compound therapy for rheumatoid arthritis. Two case reports. Joint bone spine, 2002, Volume: 69, Issue:4 Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Humans; Nail Diseases; Penicillamine; Tiopronin	2002
[Cystinuria - Cystine Stones: Recommendations for Diagnosis, Therapy and Follow-up]. Aktuelle Urologie, 2003, Volume: 34, Issue:2 Topics: Adult; Age Factors; Angiotensin-Converting Enzyme Inhibitors; Ascorbic Acid; Captopril; Chelating Agents; Child; Cystinuria; Follow-Up Studies; Humans; Kidney Calculi; Lithotripsy; Penicillamine; Time Factors; Tiopronin; Ureteroscopy	2003
Pediatric calculi: cause, prevention and medical management. Current opinion in urology, 2018, Volume: 28, Issue:5 Topics: Allopurinol; Chelating Agents; Child; Conservative Treatment; Diet; Diet Therapy; Diuretics; Diuretics, Potassium Sparing; Environment; Enzyme Inhibitors; Humans; Nephrolithiasis; Penicillamine; Potassium Citrate; Risk Factors; Sodium Chloride Symporter Inhibitors; Tiopronin	2018
The effect of additional drug therapy as metaphylaxis in patients with cystinuria: a systematic review. Minerva urologica e nefrologica = The Italian journal of urology and nephrology, 2020, Volume: 72, Issue:4 Topics: Captopril; Cystine; Cystinuria; Drug Therapy, Combination; Evidence-Based Medicine; Female; Humans; Male; Penicillamine; Tiopronin	2020
[Cystinuria]. Nephrologie & therapeutique, 2021, Volume: 17S Topics: Cystine; Cystinuria; Humans; Kidney Calculi; Penicillamine; Tiopronin	2021

Trials

5 trial(s) available for penicillamine and tiopronin

Article	Year
Management of cystine nephrolithiasis with alpha-mercaptopropionylglycine. The Journal of urology, 1986, Volume: 136, Issue:5 Topics: Adolescent; Adult; Aged; Amino Acids, Sulfur; Child; Clinical Trials as Topic; Cystine; Cystinuria; Female; Humans; Kidney Calculi; Male; Middle Aged; Penicillamine; Time Factors; Tiopronin	1986
[A comparative controlled trial of 2 administration modalities of tiopronin in rheumatoid arthritis]. Revue du rhumatisme (Ed. francaise : 1993), 1993, Volume: 60, Issue:5 Pt 2 Topics: Adult; Aged; Arthritis, Rheumatoid; Ceruloplasmin; Copper; Dose-Response Relationship, Drug; Drug Evaluation; Humans; Middle Aged; Penicillamine; Placebos; Tiopronin; Treatment Outcome	1993
Medical treatment of cystinuria: results of contemporary clinical practice. The Journal of urology, 1996, Volume: 156, Issue:5 Topics: Adolescent; Adult; Angiotensin-Converting Enzyme Inhibitors; Captopril; Child; Child, Preschool; Cystinuria; Diuretics; Female; Follow-Up Studies; Humans; Infant; Male; Middle Aged; Penicillamine; Potassium Citrate; Sodium Bicarbonate; Tiopronin; Urinary Calculi	1996
Cystinuria in children and young adults: success of monitoring free-cystine urine levels. Pediatric nephrology (Berlin, Germany), 2007, Volume: 22, Issue:11 Topics: Adolescent; Adult; Alkalies; Chelating Agents; Child; Child, Preschool; Cystine; Cystinuria; Diuretics; Drug Monitoring; Humans; Infant; Penicillamine; Potassium Citrate; Prospective Studies; Sodium Bicarbonate; Tiopronin; Urinary Calculi	2007
Effect of increasing doses of cystine-binding thiol drugs on cystine capacity in patients with cystinuria. Urolithiasis, 2019, Volume: 47, Issue:6 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cross-Over Studies; Cystine; Cystinuria; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Penicillamine; Solubility; Tiopronin; Young Adult	2019

Other Studies

57 other study(ies) available for penicillamine and tiopronin

Article	Year
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Collateral sensitivity of multidrug-resistant cells to the orphan drug tiopronin. Journal of medicinal chemistry, 2011, Jul-28, Volume: 54, Issue:14 Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; HEK293 Cells; Humans; Multidrug Resistance-Associated Proteins; Orphan Drug Production; Paclitaxel; RNA Stability; RNA, Messenger; Structure-Activity Relationship; Tiopronin	2011
[Cystine stone therapy with mercapto-propyonyl-glycine (MPG) (Thiola) (author's transl)]. Der Urologe. Ausg. A, 1975, Volume: 14, Issue:4 Topics: Adult; Amino Acids; Amino Acids, Sulfur; Cystinuria; Drug Tolerance; Female; Humans; Long-Term Care; Male; Nephrotic Syndrome; Penicillamine; Tiopronin; Urinary Calculi	1975
[The effect of treatment on circulating immune complexes in rheumatoid arthritis (author's transl)]. Deutsche medizinische Wochenschrift (1946), 1977, Mar-25, Volume: 102, Issue:12 Topics: Antigen-Antibody Complex; Arthritis, Rheumatoid; Gold; Humans; Immunosuppressive Agents; Levamisole; Penicillamine; Phagocytosis; Tiopronin	1977
Mercaptopropionylglycine: a progress in cystine stone therapy. The Journal of urology, 1977, Volume: 117, Issue:5 Topics: Adult; Amino Acids, Sulfur; Cystine; Cystinuria; Female; Follow-Up Studies; Humans; Male; Penicillamine; Tiopronin; Urinary Calculi	1977
Enalapril: a powerful in vitro non-thiol acantholytic agent. International journal of dermatology, 1992, Volume: 31, Issue:10 Topics: Acantholysis; Captopril; Culture Techniques; Enalapril; Female; Humans; Immunoglobulin G; Penicillamine; Skin; Time Factors; Tiopronin; Tissue Survival	1992
[Side-effects of treatment of 74 rheumatoid polyarthritis with tiopronin]. Revue du rhumatisme et des maladies osteo-articulaires, 1991, Volume: 58, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Drug Interactions; Female; Follow-Up Studies; Humans; Male; Middle Aged; Penicillamine; Time Factors; Tiopronin	1991
[Long-term tolerability of tiopronin (Acadione) in the treatment of rheumatoid arthritis. Apropos of 140 personal cases]. Revue du rhumatisme et des maladies osteo-articulaires, 1990, Volume: 57, Issue:2 Topics: Arthritis, Rheumatoid; Drug Eruptions; Drug Hypersensitivity; Female; Follow-Up Studies; Humans; Male; Middle Aged; Penicillamine; Retrospective Studies; Time Factors; Tiopronin	1990
Biochemical acantholysis provoked by thiol drugs. Archives of dermatology, 1990, Volume: 126, Issue:7 Topics: Acantholysis; Captopril; Humans; Pemphigus; Penicillamine; Skin Diseases; Sulfhydryl Compounds; Tiopronin	1990
Sulfur amino acid metabolism in cystinuria: a biochemical and clinical study of patients. Kidney international, 1990, Volume: 37, Issue:1 Topics: Acetylcysteine; Adult; Amino Acids, Sulfur; Cysteine; Cystinuria; Female; Homozygote; Humans; Male; Penicillamine; Tiopronin	1990
Studies on the effects of pharmacological agents on antigen-induced arthritis in BALB/c mice. Drugs under experimental and clinical research, 1987, Volume: 13, Issue:5 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens; Arthritis; Arthritis, Experimental; Azathioprine; Chloroquine; Methotrexate; Mice; Mice, Inbred BALB C; Penicillamine; Sulfapyridine; Sulfasalazine; Tiopronin	1987
Antiarthritic drugs containing thiol groups scavenge hypochlorite and inhibit its formation by myeloperoxidase from human leukocytes. A therapeutic mechanism of these drugs in rheumatoid arthritis? Arthritis and rheumatism, 1985, Volume: 28, Issue:11 Topics: Amino Acids, Sulfur; Arthritis, Rheumatoid; Aurothioglucose; Cyclohexanones; Gold Sodium Thiomalate; Humans; Hydrogen Peroxide; Hypochlorous Acid; Leukocytes; Penicillamine; Peroxidase; Tiopronin	1985
Decreased hydroxyl radical generation from polymorphonuclear leucocytes in the presence of D-penicillamine and thiopronine. Journal of clinical & laboratory immunology, 1987, Volume: 22, Issue:2 Topics: Adult; Amino Acids, Sulfur; Cell-Free System; Free Radicals; Humans; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Hydroxylation; In Vitro Techniques; Neutrophils; Penicillamine; Tiopronin; Xanthine; Xanthine Oxidase; Xanthines	1987
Effects of d-penicillamine, levamisole and tiopronin on eicosanoid synthesis by rat gut tissue. Agents and actions, 1986, Volume: 17, Issue:3-4 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Amino Acids, Sulfur; Animals; Arachidonic Acid; Arachidonic Acids; Colon; Eicosanoic Acids; In Vitro Techniques; Levamisole; Male; Penicillamine; Pyrazoles; Rats; Rats, Inbred Strains; Tiopronin	1986
[Tiopronin in 69 cases of rheumatoid polyarthritis treated earlier with D-penicillamine]. Revue du rhumatisme et des maladies osteo-articulaires, 1988, Apr-30, Volume: 55, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Amino Acids, Sulfur; Arthritis, Rheumatoid; Drug Tolerance; Female; Humans; Long-Term Care; Male; Middle Aged; Penicillamine; Tiopronin	1988
The Emory mouse cataract: the effects on cataractogenesis of alpha-tocopherol, penicillamine, triethylenetetramine, and mercaptopropionylglycine. Journal of ocular pharmacology, 1988,Fall, Volume: 4, Issue:3 Topics: Animals; Cataract; Ethylenediamines; Mice; Mice, Inbred Strains; Penicillamine; Tiopronin; Trientine; Vitamin E	1988
[Acadione, a new long-term treatment of rheumatoid polyarthritis]. Revue du rhumatisme et des maladies osteo-articulaires, 1988, Apr-30, Volume: 55, Issue:6 Topics: Amino Acids, Sulfur; Arthritis, Rheumatoid; Chemical Phenomena; Chemistry; Dose-Response Relationship, Drug; Double-Blind Method; Drug Tolerance; Female; Humans; Male; Middle Aged; Penicillamine; Tiopronin	1988
Management of the patient with cystinuria. The Urologic clinics of North America, 1987, Volume: 14, Issue:2 Topics: Adult; Alkalies; Child; Cystinuria; Dietary Proteins; Female; Fluid Therapy; Humans; Kidney Calculi; Male; Methionine; Penicillamine; Sulfhydryl Compounds; Tiopronin	1987
[Treatment of systemic scleroderma with D-penicillamine. Results in 14 patients treated for more than a year]. Revue du rhumatisme et des maladies osteo-articulaires, 1986, Volume: 53, Issue:1 Topics: Adult; Aged; Female; Follow-Up Studies; Humans; Male; Middle Aged; Penicillamine; Scleroderma, Systemic; Time Factors; Tiopronin	1986
[Tiopronine and rheumatoid polyarthritis]. Revue du rhumatisme et des maladies osteo-articulaires, 1986, Volume: 53, Issue:1 Topics: Adrenal Cortex Hormones; Amino Acids, Sulfur; Arthritis, Rheumatoid; Female; Humans; Male; Middle Aged; Penicillamine; Tiopronin	1986
Comparison of 2-mercaptopropionylglycine and D-penicillamine in the treatment of cystinuria. The Journal of urology, 1986, Volume: 136, Issue:1 Topics: Adult; Amino Acids, Sulfur; Cystinuria; Female; Humans; Male; Middle Aged; Penicillamine; Tiopronin	1986
[Spectrophotometric analysis of D-penicillamine and mercaptopropionylglycine in pharmaceutical formulations with ammonium tetrachloropalladate]. Bollettino chimico farmaceutico, 1986, Volume: 125, Issue:8 Topics: Amino Acids, Sulfur; Palladium; Penicillamine; Spectrophotometry; Tiopronin	1986
[Medical treatment of cystine lithiasis in children]. Journal d'urologie, 1984, Volume: 90, Issue:2 Topics: Amino Acids, Sulfur; Child; Cystine; Female; Humans; Male; Penicillamine; Recurrence; Tiopronin; Urinary Calculi	1984
The mechanism of biliary excretion of methyl mercury: studies with methylthiols. Acta pharmacologica et toxicologica, 1983, Volume: 53, Issue:2 Topics: Animals; Bile; Cysteine; Hydrocarbons, Iodinated; Male; Methylmercury Compounds; Penicillamine; Rats; Rats, Inbred Strains; Time Factors; Tiopronin	1983
Alternative treatment of cystinuria with alpha-merkaptopropionylglycine, Thiola. Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1983, Volume: 20 Topics: Adolescent; Adult; Aged; Amino Acids, Sulfur; Cystine; Cystinuria; Dipeptides; Female; Humans; Male; Middle Aged; Penicillamine; Tiopronin; Urinary Calculi	1983
Myopathy due to mercaptopropionyl glycine. British medical journal (Clinical research ed.), 1982, Nov-06, Volume: 285, Issue:6351 Topics: Amino Acids, Sulfur; Cystinuria; Humans; Muscular Diseases; Penicillamine; Tiopronin	1982
The influence of some thiols on biliary excretion of methyl mercury. Acta pharmacologica et toxicologica, 1983, Volume: 52, Issue:1 Topics: Animals; Bile; Cysteine; Male; Mercury; Mercury Radioisotopes; Methylmercury Compounds; Penicillamine; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Time Factors; Tiopronin	1983
[Cystinuria therapy by ascorbic acid (author's transl)]. Urologia internationalis, 1982, Volume: 37, Issue:2 Topics: Ascorbic Acid; Cysteine; Cystine; Cystinuria; Humans; Intestinal Absorption; Kidney; Penicillamine; Tiopronin	1982
Controlled multicenter trial of tiopronin and d-penicillamine for rheumatoid arthritis. Arthritis and rheumatism, 1982, Volume: 25, Issue:8 Topics: Aged; Amino Acids, Sulfur; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Blood Sedimentation; Clinical Trials as Topic; Copper; Double-Blind Method; Female; Hand; Humans; Iron; Male; Middle Aged; Penicillamine; Radiography; Rheumatoid Factor; Sulfhydryl Compounds; Tiopronin	1982
[Cystinuria: clinical and therapeutic aspects]. Bollettino chimico farmaceutico, 1982, Volume: 121, Issue:2 Topics: Adolescent; Adult; Aged; Child; Cystinuria; Drug Evaluation; Glycine; Humans; Kinetics; Middle Aged; Penicillamine; Sulfides; Thiophenes; Tiopronin	1982
Colorimetric determination of acetylcysteine, penicillamine, and mercaptopropionylglycine in pharmaceutical dosage forms. Journal of pharmaceutical sciences, 1982, Volume: 71, Issue:12 Topics: Acetylcysteine; Amino Acids, Sulfur; Capsules; Colorimetry; Penicillamine; Solutions; Spectrophotometry; Tablets; Tiopronin	1982
Drug-induced proteinuria. Contributions to nephrology, 1981, Volume: 24 Topics: Drug-Related Side Effects and Adverse Reactions; Female; Humans; Kidney; Kidney Diseases; Kidney Tubules; Male; Penicillamine; Proteinuria; Tiopronin	1981
Some pharmacological properties of tiopronin. Agents and actions, 1981, Volume: 11, Issue:6-7 Topics: Amino Acids, Sulfur; Animals; Anti-Inflammatory Agents; Carrageenan; Edema; Gossypium; Granuloma; Leukocytes; Male; Penicillamine; Pertussis Vaccine; Prostaglandins; Rats; Rats, Inbred Strains; Time Factors; Tiopronin	1981
[Sulfhydryl-based treatment of rheumatoid arthritis (penicillamine, pyrithioxin, thiopronine)]. La Revue du praticien, 1980, Apr-21, Volume: 30, Issue:23 Topics: Amino Acids, Sulfur; Arthritis, Rheumatoid; Humans; Penicillamine; Pyridines; Pyrithioxin; Sulfhydryl Compounds; Tiopronin	1980
[Tiopronine: new basic treatment for rheumatoid arthritis. Open study of 158 cases]. Revue du rhumatisme et des maladies osteo-articulaires, 1980, Volume: 47, Issue:3 Topics: Adult; Aged; Amino Acids, Sulfur; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Penicillamine; Tiopronin	1980
UV-radiation protecting efficacy of thiols, studied with UVA-induced binding of 8-MOP and CPZ to rat epidermal biomacromolecules in vivo. International journal of radiation biology, 1993, Volume: 63, Issue:4 Topics: Acetylcysteine; Animals; Captopril; Chlorpromazine; Cysteamine; Epidermis; Ergothioneine; Female; Mesna; Methoxsalen; Penicillamine; Radiation-Protective Agents; Rats; Rats, Wistar; Sulfhydryl Compounds; Tiopronin; Ultraviolet Rays	1993
Determination of penicillamine or tiopronin in pharmaceutical preparations by flow injection analysis. Journal of pharmaceutical and biomedical analysis, 1993, Volume: 11, Issue:8 Topics: Calibration; Chemistry, Pharmaceutical; Flow Injection Analysis; Palladium; Penicillamine; Tiopronin	1993
Imbalance between plasminogen activator and its inhibitors in thiol-induced acantholysis. Dermatology (Basel, Switzerland), 1993, Volume: 186, Issue:2 Topics: Acantholysis; Captopril; Culture Media; Culture Techniques; Epidermis; Humans; Penicillamine; Plasminogen Activator Inhibitor 1; Plasminogen Activators; Plasminogen Inactivators; Sulfhydryl Compounds; Tiopronin; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator	1993
Determination of thiol-containing drugs by chemiluminescence-flow injection analysis. Journal of pharmaceutical and biomedical analysis, 1993, Volume: 11, Issue:1 Topics: Acetylcysteine; Catalysis; Copper; Cysteine; Flow Injection Analysis; Hydrogen Peroxide; Hydrogen-Ion Concentration; Luminescent Measurements; Luminol; Penicillamine; Sulfhydryl Compounds; Tiopronin	1993
Urinary excretion of metals during treatment with D-penicillamine and 2-mercaptopropionylglycine in normal and cystinuric dogs. Journal of veterinary pharmacology and therapeutics, 1993, Volume: 16, Issue:1 Topics: Administration, Oral; Animals; Creatinine; Cystinuria; Dog Diseases; Dogs; Injections, Intravenous; Longitudinal Studies; Male; Metals; Penicillamine; Tiopronin	1993
Mitigation of nitrofurantoin-induced toxicity in the perfused rat liver. Human & experimental toxicology, 1996, Volume: 15, Issue:5 Topics: Acetylcysteine; Adenosine Monophosphate; Animals; Anti-Infective Agents, Urinary; Antidotes; Cell Death; Chelating Agents; Dithiothreitol; Egtazic Acid; Free Radical Scavengers; Free Radicals; Glutathione; L-Lactate Dehydrogenase; Liver; Male; Nitrofurantoin; Oxidation-Reduction; Oxidative Stress; Penicillamine; Perfusion; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds; Sulfobromophthalein; Tiopronin	1996
Flow-injection fluorimetric determination of penicillamine and tiopronin in pharmaceutical preparations. Journal of pharmaceutical and biomedical analysis, 1996, Volume: 15, Issue:1 Topics: Capsules; Chelating Agents; Drug Contamination; Fluorometry; Penicillamine; Tiopronin	1996
Clinical aspects of cystinuria. Contributions to nephrology, 1997, Volume: 122 Topics: Adolescent; Adult; Chelating Agents; Child; Child, Preschool; Cystine; Cystinuria; Diet; Female; Humans; Kidney Calculi; Male; Middle Aged; Pedigree; Penicillamine; Risk Factors; Solubility; Tiopronin	1997
Therapeutic effect of tiopronin following D-penicillamine toxicity in a patient with rheumatoid arthritis. Clinical rheumatology, 1998, Volume: 17, Issue:1 Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Humans; Jaundice; Male; Penicillamine; Retreatment; Tiopronin	1998
[Clinical study on cystinuria in children--the stone management and the prevention of calculi recurrence]. Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1998, Volume: 89, Issue:9 Topics: Adolescent; Adult; Child; Child, Preschool; Cystinuria; Female; Follow-Up Studies; Humans; Infant; Lithotripsy; Male; Methionine; Penicillamine; Retrospective Studies; Secondary Prevention; Sodium Bicarbonate; Tiopronin; Urinary Calculi; Urologic Surgical Procedures	1998
The long-term outcome of cystinuria in Japan. Urologia internationalis, 1998, Volume: 61, Issue:2 Topics: Adult; Chelating Agents; Cystine; Cystinuria; Female; Follow-Up Studies; Humans; Hydrogen-Ion Concentration; Japan; Male; Penicillamine; Recurrence; Tiopronin; Treatment Outcome; Urinary Calculi	1998
A modified cyanide-nitroprusside method for quantifying urinary cystine concentration that corrects for creatinine interference. Clinica chimica acta; international journal of clinical chemistry, 1999, Volume: 289, Issue:1-2 Topics: Adult; Artifacts; Ascorbic Acid; Captopril; Chlorides; Colorimetry; Creatinine; Cyanides; Cysteine; Cystinuria; Dose-Response Relationship, Drug; Female; Ferrous Compounds; Humans; Male; Middle Aged; Nitroprusside; Penicillamine; Reference Values; Reproducibility of Results; Serum Albumin; Tiopronin; Zinc Compounds	1999
Effects of sulfhydryl compounds on interleukin-1-induced vascular endothelial growth factor production in human synovial stromal cells. Biological & pharmaceutical bulletin, 2000, Volume: 23, Issue:5 Topics: Acetylcysteine; Cells, Cultured; Cysteine; Endothelial Growth Factors; Humans; Interleukin-1; Lymphokines; Penicillamine; Stromal Cells; Sulfhydryl Compounds; Synovial Membrane; Tiopronin; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors	2000
Solid phase assay of urine cystine supersaturation in the presence of cystine binding drugs. The Journal of urology, 2001, Volume: 166, Issue:2 Topics: Buffers; Captopril; Chemical Phenomena; Chemistry; Crystallization; Cystinuria; Humans; Penicillamine; Tiopronin	2001
Cystine analyses of separate day and night urine as a basis for the management of patients with homozygous cystinuria. Urological research, 2001, Volume: 29, Issue:5 Topics: Adult; Aged; Circadian Rhythm; Cystinuria; Dose-Response Relationship, Drug; Female; Homozygote; Humans; Male; Mesna; Middle Aged; Osmolar Concentration; Penicillamine; Specimen Handling; Sulfhydryl Compounds; Tiopronin; Urinary Calculi	2001
Urinary excretion of total cystine and the dibasic amino acids arginine, lysine and ornithine in relation to genetic findings in patients with cystinuria treated with sulfhydryl compounds. Urological research, 2003, Volume: 31, Issue:6 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Amino Acid Transport Systems, Basic; Amino Acids, Diamino; Arginine; Carrier Proteins; Cystine; Cystinuria; Female; Humans; Lysine; Male; Membrane Glycoproteins; Middle Aged; Mutation; Ornithine; Penicillamine; Sulfhydryl Compounds; Tiopronin	2003
Studies of urinary cystine precipitation in vitro: ontogeny of cystine nephrolithiasis and identification of meso-2,3-dimercaptosuccinic acid as a potential therapy for cystinuria. Molecular genetics and metabolism, 2003, Volume: 80, Issue:4 Topics: Adolescent; Age Factors; Chemical Precipitation; Child; Child, Preschool; Cystine; Cystinuria; Dose-Response Relationship, Drug; Humans; Infant; Kidney Diseases; Lithiasis; Penicillamine; Reference Values; Succimer; Tiopronin; Urine	2003
Effect of cystine-binding thiol drugs on urinary cystine capacity in patients with cystinuria. Journal of endourology, 2005, Volume: 19, Issue:3 Topics: Administration, Oral; Adult; Captopril; Case-Control Studies; Cysteine; Cystinuria; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Middle Aged; Penicillamine; Probability; Prospective Studies; Reference Values; Risk Assessment; Tiopronin; Treatment Outcome; Urinalysis	2005
Simultaneous determination of tiopronin and d-penicillamine in human urine by liquid chromatography with ultraviolet detection. Analytica chimica acta, 2007, May-02, Volume: 590, Issue:1 Topics: Humans; Penicillamine; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Tiopronin	2007
Effect of thiol drugs on tert-butyl hydroperoxide induced luminol chemiluminescence in human erythrocytes, erythrocyte lysate, and erythrocyte membranes. Chemico-biological interactions, 2010, Jul-30, Volume: 186, Issue:2 Topics: Acetylcysteine; Erythrocyte Membrane; Erythrocytes; Humans; In Vitro Techniques; Kinetics; Luminescence; Luminol; Mesna; Models, Biological; Oxidative Stress; Penicillamine; Sulfhydryl Compounds; tert-Butylhydroperoxide; Tiopronin	2010
Adverse events associated with currently used medical treatments for cystinuria and treatment goals: results from a series of 442 patients in France. BJU international, 2019, Volume: 124, Issue:5 Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Cystinuria; Drug-Related Side Effects and Adverse Reactions; Female; France; Humans; Hydrogen-Ion Concentration; Infant; Male; Middle Aged; Penicillamine; Retrospective Studies; Sodium Bicarbonate; Tiopronin; Treatment Outcome; Urinalysis; Young Adult	2019