penicillamine and proline

penicillamine has been researched along with proline in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199023 (71.88)18.7374
1990's5 (15.63)18.2507
2000's3 (9.38)29.6817
2010's1 (3.13)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nakagawa, H; Ohkoshi, K; Tsurufuji, S1
Bressan, GM; Prockop, DJ1
Dunne, M; Molteni, A; Solliday, NH; Ts'ao, CH; Ward, WF1
Last, JA1
Elling, H; Elling, P1
Kürten, I; Ruiz-Torres, A1
Ruiz-Torres, A2
Cramér, K; Goyer, RA; Jagenburg, R; Wilson, MH1
Freeman, HC1
Uitto, J1
Klein, L; Nowacek, CJ1
Lukens, LN1
Henneman, DH1
Helin, P; Lorenzen, I; Rasmussen, O; Uitto, J1
Nimni, ME2
Hahn, EG; Martini, GA; Ott, U1
Chamson, A; Frey, J1
Bird, HA; Dixon, JS; Martin, MF; McKenna, F; Surrall, KE; Wright, V1
Breckenridge, AM; Park, BK; Yeung, JH1
Andres, GA; Brentjens, JR; Donker, AJ; Venuto, RC; Vladutiu, AO1
Clement, M; Parfrey, PS; Vandenburg, MJ; Wright, P1
Chen, DZ; Katsura, M; Kuriyama, K; Narihara, H; Ohkuma, S1
Craven, PA; DeRubertis, FR; Felder, J; Phillips, S; Studer, RK1
Cao, M; Evans, CH; Georgescu, HI; Hebda, PA; Kavalkovich, K; Niyibizi, C; Rizzo, CF; Stefanovic-Racic, M; Westerhausen-Larson, A1
Arai, M; Kondo, A; Mogi, M; Nagatsu, T; Togari, A1
Caruso, U; Fantasia, A; Galietta, LJ; Gazzolo, A; Musante, L; Romano, L; Romio, L; Rossi, GA; Sacco, O; Varesio, L; Zegarra-Moran, O1
Bélec, L; Lubell, WD; Maletinska, L; Slaninová, J1
Carru, C; Deiana, L; Pinna, GA; Pisanu, E; Sotgia, S; Zinellu, A1
Bugg, CW; Dunn, DE; Khoshnan, A; Lo, DC; Patterson, PH; Southwell, AL1
Ianni, F; Natalini, B; Sardella, R1

Reviews

3 review(s) available for penicillamine and proline

ArticleYear
Changes in the collagen pathway in fibrosis.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1985, Volume: 5, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Colchicine; Collagen; Connective Tissue Diseases; Cross-Linking Reagents; Disease Models, Animal; Humans; Kinetics; Liver; Liver Cirrhosis; Lung; Organ Size; Ozone; Penicillamine; Proline; Pulmonary Fibrosis; Rats

1985
Crystal structures of metal-peptide complexes.
    Advances in protein chemistry, 1967, Volume: 22

    Topics: Alanine; Aminobutyrates; Aspartic Acid; Binding Sites; Biureas; Cadmium; Chelating Agents; Computers; Copper; Crystallography; Dipeptides; Glutamates; Glycine; Histidine; Imidazoles; Mercury; Metals; Models, Chemical; Nickel; Penicillamine; Peptides; Proline; Silver; Stereoisomerism; Water; Zinc

1967
[Liver fibrosis. 2].
    Zeitschrift fur Gastroenterologie, 1980, Volume: 18, Issue:10

    Topics: Acetylglucosaminidase; Aminopropionitrile; Animals; Collagen; Connective Tissue; Female; Fibroblasts; Humans; Hydrocortisone; Liver; Liver Cirrhosis; Liver Cirrhosis, Alcoholic; Male; Papio; Penicillamine; Procollagen; Procollagen-Proline Dioxygenase; Proline; Protein-Lysine 6-Oxidase; Rats

1980

Trials

1 trial(s) available for penicillamine and proline

ArticleYear
Captopril: a new treatment for rheumatoid arthritis?
    Lancet (London, England), 1984, Jun-16, Volume: 1, Issue:8390

    Topics: Adult; Aged; Arthritis, Rheumatoid; Captopril; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hypotension; Male; Middle Aged; Penicillamine; Proline

1984

Other Studies

28 other study(ies) available for penicillamine and proline

ArticleYear
Selective inhibition of collagen synthesis by D-penicillamine in carrageenin-induced inflammation in rats.
    Biochemical pharmacology, 1979, Jun-01, Volume: 28, Issue:11

    Topics: Animals; Carrageenan; Collagen; Ferrous Compounds; Hydroxylation; Inflammation; Male; Penicillamine; Procollagen; Procollagen-Proline Dioxygenase; Proline; Rats; Solubility

1979
Synthesis of elastin in aortas from chick embryos. Conversion of newly secreted elastin to cross-linked elastin without apparent proteolysis of the molecule.
    Biochemistry, 1977, Apr-05, Volume: 16, Issue:7

    Topics: Animals; Aorta; Chick Embryo; Elastin; Kinetics; Macromolecular Substances; Molecular Weight; Penicillamine; Proline; Protein Biosynthesis

1977
Monocrotaline-induced pulmonary fibrosis in rats: amelioration by captopril and penicillamine.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1985, Volume: 180, Issue:1

    Topics: Animals; Body Weight; Captopril; Hydroxyproline; Lung; Male; Monocrotaline; Organ Size; Penicillamine; Peptidyl-Dipeptidase A; Plants, Toxic; Proline; Pulmonary Fibrosis; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Senecio

1985
Penicillamine, captopril, and hypoglycemia.
    Annals of internal medicine, 1985, Volume: 103, Issue:4

    Topics: Adult; Captopril; Diabetes Mellitus; Female; Humans; Hypoglycemia; Male; Middle Aged; Penicillamine; Proline

1985
[Penicillamine effect on the hydroxylation of proline and lysine].
    Klinische Wochenschrift, 1973, Jan-15, Volume: 51, Issue:2

    Topics: Animals; Carbon Isotopes; Collagen; Hydroxylation; Lysine; Mixed Function Oxygenases; Penicillamine; Procollagen-Proline Dioxygenase; Proline; Rats

1973
[Effect of penicillamine on collagen synthesis].
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:1

    Topics: Administration, Oral; Animals; Body Weight; Carbon Radioisotopes; Collagen; Hydroxyproline; Male; Penicillamine; Proline; Rats; Time Factors; Tropocollagen

1974
Renal ultrastructure, renal function, and parameters of lead toxicity in workers with different periods of lead exposure.
    British journal of industrial medicine, 1974, Volume: 31, Issue:2

    Topics: Adult; Alanine Transaminase; Alcohol Drinking; Environmental Exposure; Glomerular Filtration Rate; Humans; Kidney; Lead; Lead Poisoning; Male; Metallurgy; Microscopy, Electron; Middle Aged; Occupational Diseases; Penicillamine; Phenylephrine; Proline; Time Factors; Tyrosine; Valine

1974
Effect of D-penicillamine on collagen biosynthesis in organ culture.
    Biochimica et biophysica acta, 1969, Dec-23, Volume: 194, Issue:2

    Topics: Animals; Bone and Bones; Carbon Isotopes; Collagen; Culture Media; Depression, Chemical; Dialysis; Female; Hydroxyproline; Iron; Kinetics; Mice; Mixed Function Oxygenases; Organ Culture Techniques; Penicillamine; Pregnancy; Proline; Protein Biosynthesis; Ulna

1969
Effect of penicillamine on new and pre-existing (3H) collagen in vivo.
    Biochimica et biophysica acta, 1969, Dec-23, Volume: 194, Issue:2

    Topics: Animals; Body Weight; Collagen; Homeostasis; Hydrogen-Ion Concentration; Hydroxyproline; Male; Metabolism; Penicillamine; Proline; Rats; Skin; Solubility; Stimulation, Chemical; Time Factors; Tritium

1969
The formation of collagen alpha chains in the absence of proline hydroxylation.
    The Journal of biological chemistry, 1970, Feb-10, Volume: 245, Issue:3

    Topics: Age Factors; Animals; Buffers; Carbon Isotopes; Chick Embryo; Chromatography, Gel; Chromatography, Ion Exchange; Collagen; Electrophoresis, Disc; Foot; Lathyrism; Lysine; Methods; Methylcellulose; Nitriles; Penicillamine; Peptide Biosynthesis; Proline; Pyridines; Tibia; Tritium; Urea

1970
Inhibition of the effect of D-penicillamine on collagen solubility in skin by 17-beta-estradiol cypionate; and the effect of D-penicillamine and 17-beta-estradiol on the abnormalities in rat bone produced by a low calcium diet.
    Endocrinology, 1970, Volume: 87, Issue:3

    Topics: Animals; Aorta; Bone and Bones; Calcium, Dietary; Carbon Isotopes; Carrageenan; Collagen; Deficiency Diseases; Drug Antagonism; Estradiol; Female; Granuloma; Guinea Pigs; Hydroxyproline; In Vitro Techniques; Metabolic Diseases; Penicillamine; Proline; Rats; Skin; Solubility; Stereoisomerism

1970
Skin collagen in patients with scleroderma: biosynthesis and maturation in vitro, and the effect of D-penicillamine.
    Annals of clinical research, 1970, Volume: 2, Issue:3

    Topics: Adult; Aged; Biopsy; Carbon Isotopes; Collagen; Female; Humans; Hydroxyproline; In Vitro Techniques; Male; Middle Aged; Mixed Function Oxygenases; Penicillamine; Proline; Scleroderma, Systemic; Skin

1970
A defect in the intramolecular and intermolecular cross-linking of collagen caused by penicillamine. I. Metabolic and functional abnormalities in soft tissues.
    The Journal of biological chemistry, 1968, Apr-10, Volume: 243, Issue:7

    Topics: Aminopropionitrile; Animals; Biomechanical Phenomena; Carbon Isotopes; Collagen; Electrophoresis, Disc; Male; Penicillamine; Proline; Rats; Skin; Skin Physiological Phenomena; Solubility; Temperature; Ultracentrifugation

1968
[On the mechanism of the penicillamine action on collagen metabolism].
    Arzneimittel-Forschung, 1968, Volume: 18, Issue:5

    Topics: Amino Acids; Animals; Blood Proteins; Carbon Isotopes; Chromatography, Thin Layer; Collagen; Femur; Glycine; Liver; Male; Penicillamine; Proline; Protein Binding; Rats; Skin; Tendons; Tyrosine

1968
Accumulation of a collagen precursor in the skin of penicillamine-treated rats.
    Biochimica et biophysica acta, 1965, Dec-16, Volume: 111, Issue:2

    Topics: Aminopropionitrile; Animals; Collagen; In Vitro Techniques; Lathyrism; Penicillamine; Proline; Rats; Skin; Ultracentrifugation

1965
[Cytopharmacology in fibroblast culture].
    Annales de l'anesthesiologie francaise, 1980, Volume: 21, Issue:6

    Topics: Cells, Cultured; Collagen; Fibroblasts; Humans; Penicillamine; Proline; Smoking; Toxicology

1980
Drug protein conjugates--VI. Role of glutathione in the metabolism of captopril and captopril plasma protein conjugates.
    Biochemical pharmacology, 1983, Dec-01, Volume: 32, Issue:23

    Topics: Acetaminophen; Alanine Transaminase; Animals; Ascorbic Acid; Blood Proteins; Captopril; Cysteine; Glutathione; Liver; Male; Mice; Mice, Inbred CBA; Penicillamine; Proline; Protein Binding; Rats; Rats, Inbred Strains

1983
Effects of prolonged administration of D-penicillamine or captopril in various strains of rats. Brown Norway rats treated with D-penicillamine develop autoantibodies, circulating immune complexes, and disseminated intravascular coagulation.
    Clinical immunology and immunopathology, 1984, Volume: 30, Issue:1

    Topics: Animals; Antibodies, Antinuclear; Antigen-Antibody Complex; Autoantibodies; Autoimmune Diseases; Basement Membrane; Captopril; Disseminated Intravascular Coagulation; Female; Immunoglobulin G; Kidney Glomerulus; Male; Penicillamine; Proline; Pulmonary Alveoli; Rats; Rats, Inbred BN; Rats, Inbred Lew; Rats, Inbred Strains

1984
Captopril-induced pemphigus.
    British medical journal, 1980, Jul-19, Volume: 281, Issue:6234

    Topics: Captopril; Chemical Phenomena; Chemistry; Humans; Male; Middle Aged; Pemphigus; Penicillamine; Proline

1980
Nitric oxide-evoked [3H] gamma-aminobutyric acid release is mediated by two distinct release mechanisms.
    Brain research. Molecular brain research, 1996, Volume: 36, Issue:1

    Topics: Animals; Biological Transport; Calcium; Cells, Cultured; Cerebral Cortex; gamma-Aminobutyric Acid; Mice; Neurons; Nipecotic Acids; Nitric Oxide; Nitroprusside; Oximes; Penicillamine; Proline; S-Nitroso-N-Acetylpenicillamine; Sodium; Tritium

1996
Nitric oxide inhibition of transforming growth factor-beta and collagen synthesis in mesangial cells.
    Diabetes, 1997, Volume: 46, Issue:4

    Topics: Animals; Captopril; Cattle; Cells, Cultured; Coculture Techniques; Collagen; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Glomerular Mesangium; Glucose; Indoles; Maleimides; Nitric Oxide; omega-N-Methylarginine; Osmolar Concentration; Penicillamine; Proline; Protein Kinase C; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Time Factors; Transforming Growth Factor beta; Tritium

1997
Nitric oxide inhibits the synthesis of type-II collagen without altering Col2A1 mRNA abundance: prolyl hydroxylase as a possible target.
    The Biochemical journal, 1997, May-15, Volume: 324 ( Pt 1)

    Topics: Animals; Cartilage, Articular; Cells, Cultured; Collagen; Enzyme Inhibitors; Humans; Interleukin-1; Methionine; Nitric Oxide; omega-N-Methylarginine; Penicillamine; Procollagen-Proline Dioxygenase; Proline; Protein Biosynthesis; Rabbits; Recombinant Proteins; RNA Processing, Post-Transcriptional; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine

1997
Coexpression of GTP cyclohydrolase I and inducible nitric oxide synthase mRNAs in mouse osteoblastic cells activated by proinflammatory cytokines.
    FEBS letters, 1998, May-29, Volume: 428, Issue:3

    Topics: 3T3 Cells; Animals; Apoptosis; Biopterins; Cell Nucleus; Cell Survival; Curcumin; Cytokines; DNA Fragmentation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; GTP Cyclohydrolase; Hypoxanthines; Interferon-gamma; Interleukin-1; Kinetics; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Osteoblasts; Penicillamine; Proline; Pteridines; Pterins; Recombinant Proteins; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Thiocarbamates; Transcription Factor AP-1; Transcription, Genetic; Transfection; Tumor Necrosis Factor-alpha

1998
An electrogenic amino acid transporter in the apical membrane of cultured human bronchial epithelial cells.
    The American journal of physiology, 1998, Volume: 275, Issue:5

    Topics: Alanine; Amiloride; Amino Acid Transport Systems; Amino Acids; Arginine; Bronchi; Carrier Proteins; Cell Membrane; Cells, Cultured; Epithelial Cells; Humans; Kinetics; Lysine; Membrane Potentials; Nitric Oxide Donors; Penicillamine; Proline; S-Nitroso-N-Acetylpenicillamine

1998
The influence of steric interactions on the conformation and biology of oxytocin. Synthesis and analysis of penicillamine(6)-oxytocin and penicillamine(6)-5-tert-butylproline(7)-oxytocin analogs.
    The journal of peptide research : official journal of the American Peptide Society, 2001, Volume: 58, Issue:3

    Topics: Animals; Female; Molecular Conformation; Oxytocin; Penicillamine; Proline; Rats; Stereoisomerism; Structure-Activity Relationship; Uterus

2001
Enantiomeric reversed-phase high-performance liquid chromatography resolution of D-/L-penicillamine after spirocyclization with ninhydrin and by using copper(II)-L-proline complex as a chiral selector in the mobile phase.
    Journal of chromatography. A, 2008, Sep-26, Volume: 1205, Issue:1-2

    Topics: Chromatography, High Pressure Liquid; Copper; Ninhydrin; Penicillamine; Proline; Spiro Compounds; Stereoisomerism

2008
Intrabodies binding the proline-rich domains of mutant huntingtin increase its turnover and reduce neurotoxicity.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Sep-03, Volume: 28, Issue:36

    Topics: Animals; Antibodies; Antibody Specificity; Brain; Cell Line, Transformed; Disease Models, Animal; Epitope Mapping; Humans; Huntingtin Protein; Immunoglobulin Variable Region; In Vitro Techniques; Luminescent Proteins; Mutation; Nerve Tissue Proteins; Neurotoxicity Syndromes; Nuclear Proteins; Penicillamine; Peptides; Proline; Protein Binding; Protein Structure, Tertiary; Transfection

2008
Enantioseparations by high-performance liquid chromatography based on chiral ligand-exchange.
    Methods in molecular biology (Clifton, N.J.), 2013, Volume: 970

    Topics: Chromatography, High Pressure Liquid; Cysteine; Hydroxyproline; Ligands; Molecular Structure; Penicillamine; Phenylalanine; Proline; Silica Gel; Stereoisomerism

2013