penicillamine has been researched along with proline in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (71.88) | 18.7374 |
| 1990's | 5 (15.63) | 18.2507 |
| 2000's | 3 (9.38) | 29.6817 |
| 2010's | 1 (3.13) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nakagawa, H; Ohkoshi, K; Tsurufuji, S | 1 |
| Bressan, GM; Prockop, DJ | 1 |
| Dunne, M; Molteni, A; Solliday, NH; Ts'ao, CH; Ward, WF | 1 |
| Last, JA | 1 |
| Elling, H; Elling, P | 1 |
| Kürten, I; Ruiz-Torres, A | 1 |
| Ruiz-Torres, A | 2 |
| Cramér, K; Goyer, RA; Jagenburg, R; Wilson, MH | 1 |
| Freeman, HC | 1 |
| Uitto, J | 1 |
| Klein, L; Nowacek, CJ | 1 |
| Lukens, LN | 1 |
| Henneman, DH | 1 |
| Helin, P; Lorenzen, I; Rasmussen, O; Uitto, J | 1 |
| Nimni, ME | 2 |
| Hahn, EG; Martini, GA; Ott, U | 1 |
| Chamson, A; Frey, J | 1 |
| Bird, HA; Dixon, JS; Martin, MF; McKenna, F; Surrall, KE; Wright, V | 1 |
| Breckenridge, AM; Park, BK; Yeung, JH | 1 |
| Andres, GA; Brentjens, JR; Donker, AJ; Venuto, RC; Vladutiu, AO | 1 |
| Clement, M; Parfrey, PS; Vandenburg, MJ; Wright, P | 1 |
| Chen, DZ; Katsura, M; Kuriyama, K; Narihara, H; Ohkuma, S | 1 |
| Craven, PA; DeRubertis, FR; Felder, J; Phillips, S; Studer, RK | 1 |
| Cao, M; Evans, CH; Georgescu, HI; Hebda, PA; Kavalkovich, K; Niyibizi, C; Rizzo, CF; Stefanovic-Racic, M; Westerhausen-Larson, A | 1 |
| Arai, M; Kondo, A; Mogi, M; Nagatsu, T; Togari, A | 1 |
| Caruso, U; Fantasia, A; Galietta, LJ; Gazzolo, A; Musante, L; Romano, L; Romio, L; Rossi, GA; Sacco, O; Varesio, L; Zegarra-Moran, O | 1 |
| Bélec, L; Lubell, WD; Maletinska, L; Slaninová, J | 1 |
| Carru, C; Deiana, L; Pinna, GA; Pisanu, E; Sotgia, S; Zinellu, A | 1 |
| Bugg, CW; Dunn, DE; Khoshnan, A; Lo, DC; Patterson, PH; Southwell, AL | 1 |
| Ianni, F; Natalini, B; Sardella, R | 1 |
3 review(s) available for penicillamine and proline
| Article | Year |
|---|---|
Changes in the collagen pathway in fibrosis.
Topics: Animals; Anti-Inflammatory Agents; Colchicine; Collagen; Connective Tissue Diseases; Cross-Linking Reagents; Disease Models, Animal; Humans; Kinetics; Liver; Liver Cirrhosis; Lung; Organ Size; Ozone; Penicillamine; Proline; Pulmonary Fibrosis; Rats | 1985 |
Crystal structures of metal-peptide complexes.
Topics: Alanine; Aminobutyrates; Aspartic Acid; Binding Sites; Biureas; Cadmium; Chelating Agents; Computers; Copper; Crystallography; Dipeptides; Glutamates; Glycine; Histidine; Imidazoles; Mercury; Metals; Models, Chemical; Nickel; Penicillamine; Peptides; Proline; Silver; Stereoisomerism; Water; Zinc | 1967 |
[Liver fibrosis. 2].
Topics: Acetylglucosaminidase; Aminopropionitrile; Animals; Collagen; Connective Tissue; Female; Fibroblasts; Humans; Hydrocortisone; Liver; Liver Cirrhosis; Liver Cirrhosis, Alcoholic; Male; Papio; Penicillamine; Procollagen; Procollagen-Proline Dioxygenase; Proline; Protein-Lysine 6-Oxidase; Rats | 1980 |
1 trial(s) available for penicillamine and proline
| Article | Year |
|---|---|
Captopril: a new treatment for rheumatoid arthritis?
Topics: Adult; Aged; Arthritis, Rheumatoid; Captopril; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hypotension; Male; Middle Aged; Penicillamine; Proline | 1984 |
28 other study(ies) available for penicillamine and proline
| Article | Year |
|---|---|
Selective inhibition of collagen synthesis by D-penicillamine in carrageenin-induced inflammation in rats.
Topics: Animals; Carrageenan; Collagen; Ferrous Compounds; Hydroxylation; Inflammation; Male; Penicillamine; Procollagen; Procollagen-Proline Dioxygenase; Proline; Rats; Solubility | 1979 |
Synthesis of elastin in aortas from chick embryos. Conversion of newly secreted elastin to cross-linked elastin without apparent proteolysis of the molecule.
Topics: Animals; Aorta; Chick Embryo; Elastin; Kinetics; Macromolecular Substances; Molecular Weight; Penicillamine; Proline; Protein Biosynthesis | 1977 |
Monocrotaline-induced pulmonary fibrosis in rats: amelioration by captopril and penicillamine.
Topics: Animals; Body Weight; Captopril; Hydroxyproline; Lung; Male; Monocrotaline; Organ Size; Penicillamine; Peptidyl-Dipeptidase A; Plants, Toxic; Proline; Pulmonary Fibrosis; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Senecio | 1985 |
Penicillamine, captopril, and hypoglycemia.
Topics: Adult; Captopril; Diabetes Mellitus; Female; Humans; Hypoglycemia; Male; Middle Aged; Penicillamine; Proline | 1985 |
[Penicillamine effect on the hydroxylation of proline and lysine].
Topics: Animals; Carbon Isotopes; Collagen; Hydroxylation; Lysine; Mixed Function Oxygenases; Penicillamine; Procollagen-Proline Dioxygenase; Proline; Rats | 1973 |
[Effect of penicillamine on collagen synthesis].
Topics: Administration, Oral; Animals; Body Weight; Carbon Radioisotopes; Collagen; Hydroxyproline; Male; Penicillamine; Proline; Rats; Time Factors; Tropocollagen | 1974 |
Renal ultrastructure, renal function, and parameters of lead toxicity in workers with different periods of lead exposure.
Topics: Adult; Alanine Transaminase; Alcohol Drinking; Environmental Exposure; Glomerular Filtration Rate; Humans; Kidney; Lead; Lead Poisoning; Male; Metallurgy; Microscopy, Electron; Middle Aged; Occupational Diseases; Penicillamine; Phenylephrine; Proline; Time Factors; Tyrosine; Valine | 1974 |
Effect of D-penicillamine on collagen biosynthesis in organ culture.
Topics: Animals; Bone and Bones; Carbon Isotopes; Collagen; Culture Media; Depression, Chemical; Dialysis; Female; Hydroxyproline; Iron; Kinetics; Mice; Mixed Function Oxygenases; Organ Culture Techniques; Penicillamine; Pregnancy; Proline; Protein Biosynthesis; Ulna | 1969 |
Effect of penicillamine on new and pre-existing (3H) collagen in vivo.
Topics: Animals; Body Weight; Collagen; Homeostasis; Hydrogen-Ion Concentration; Hydroxyproline; Male; Metabolism; Penicillamine; Proline; Rats; Skin; Solubility; Stimulation, Chemical; Time Factors; Tritium | 1969 |
The formation of collagen alpha chains in the absence of proline hydroxylation.
Topics: Age Factors; Animals; Buffers; Carbon Isotopes; Chick Embryo; Chromatography, Gel; Chromatography, Ion Exchange; Collagen; Electrophoresis, Disc; Foot; Lathyrism; Lysine; Methods; Methylcellulose; Nitriles; Penicillamine; Peptide Biosynthesis; Proline; Pyridines; Tibia; Tritium; Urea | 1970 |
Inhibition of the effect of D-penicillamine on collagen solubility in skin by 17-beta-estradiol cypionate; and the effect of D-penicillamine and 17-beta-estradiol on the abnormalities in rat bone produced by a low calcium diet.
Topics: Animals; Aorta; Bone and Bones; Calcium, Dietary; Carbon Isotopes; Carrageenan; Collagen; Deficiency Diseases; Drug Antagonism; Estradiol; Female; Granuloma; Guinea Pigs; Hydroxyproline; In Vitro Techniques; Metabolic Diseases; Penicillamine; Proline; Rats; Skin; Solubility; Stereoisomerism | 1970 |
Skin collagen in patients with scleroderma: biosynthesis and maturation in vitro, and the effect of D-penicillamine.
Topics: Adult; Aged; Biopsy; Carbon Isotopes; Collagen; Female; Humans; Hydroxyproline; In Vitro Techniques; Male; Middle Aged; Mixed Function Oxygenases; Penicillamine; Proline; Scleroderma, Systemic; Skin | 1970 |
A defect in the intramolecular and intermolecular cross-linking of collagen caused by penicillamine. I. Metabolic and functional abnormalities in soft tissues.
Topics: Aminopropionitrile; Animals; Biomechanical Phenomena; Carbon Isotopes; Collagen; Electrophoresis, Disc; Male; Penicillamine; Proline; Rats; Skin; Skin Physiological Phenomena; Solubility; Temperature; Ultracentrifugation | 1968 |
[On the mechanism of the penicillamine action on collagen metabolism].
Topics: Amino Acids; Animals; Blood Proteins; Carbon Isotopes; Chromatography, Thin Layer; Collagen; Femur; Glycine; Liver; Male; Penicillamine; Proline; Protein Binding; Rats; Skin; Tendons; Tyrosine | 1968 |
Accumulation of a collagen precursor in the skin of penicillamine-treated rats.
Topics: Aminopropionitrile; Animals; Collagen; In Vitro Techniques; Lathyrism; Penicillamine; Proline; Rats; Skin; Ultracentrifugation | 1965 |
[Cytopharmacology in fibroblast culture].
Topics: Cells, Cultured; Collagen; Fibroblasts; Humans; Penicillamine; Proline; Smoking; Toxicology | 1980 |
Drug protein conjugates--VI. Role of glutathione in the metabolism of captopril and captopril plasma protein conjugates.
Topics: Acetaminophen; Alanine Transaminase; Animals; Ascorbic Acid; Blood Proteins; Captopril; Cysteine; Glutathione; Liver; Male; Mice; Mice, Inbred CBA; Penicillamine; Proline; Protein Binding; Rats; Rats, Inbred Strains | 1983 |
Effects of prolonged administration of D-penicillamine or captopril in various strains of rats. Brown Norway rats treated with D-penicillamine develop autoantibodies, circulating immune complexes, and disseminated intravascular coagulation.
Topics: Animals; Antibodies, Antinuclear; Antigen-Antibody Complex; Autoantibodies; Autoimmune Diseases; Basement Membrane; Captopril; Disseminated Intravascular Coagulation; Female; Immunoglobulin G; Kidney Glomerulus; Male; Penicillamine; Proline; Pulmonary Alveoli; Rats; Rats, Inbred BN; Rats, Inbred Lew; Rats, Inbred Strains | 1984 |
Captopril-induced pemphigus.
Topics: Captopril; Chemical Phenomena; Chemistry; Humans; Male; Middle Aged; Pemphigus; Penicillamine; Proline | 1980 |
Nitric oxide-evoked [3H] gamma-aminobutyric acid release is mediated by two distinct release mechanisms.
Topics: Animals; Biological Transport; Calcium; Cells, Cultured; Cerebral Cortex; gamma-Aminobutyric Acid; Mice; Neurons; Nipecotic Acids; Nitric Oxide; Nitroprusside; Oximes; Penicillamine; Proline; S-Nitroso-N-Acetylpenicillamine; Sodium; Tritium | 1996 |
Nitric oxide inhibition of transforming growth factor-beta and collagen synthesis in mesangial cells.
Topics: Animals; Captopril; Cattle; Cells, Cultured; Coculture Techniques; Collagen; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Glomerular Mesangium; Glucose; Indoles; Maleimides; Nitric Oxide; omega-N-Methylarginine; Osmolar Concentration; Penicillamine; Proline; Protein Kinase C; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Time Factors; Transforming Growth Factor beta; Tritium | 1997 |
Nitric oxide inhibits the synthesis of type-II collagen without altering Col2A1 mRNA abundance: prolyl hydroxylase as a possible target.
Topics: Animals; Cartilage, Articular; Cells, Cultured; Collagen; Enzyme Inhibitors; Humans; Interleukin-1; Methionine; Nitric Oxide; omega-N-Methylarginine; Penicillamine; Procollagen-Proline Dioxygenase; Proline; Protein Biosynthesis; Rabbits; Recombinant Proteins; RNA Processing, Post-Transcriptional; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine | 1997 |
Coexpression of GTP cyclohydrolase I and inducible nitric oxide synthase mRNAs in mouse osteoblastic cells activated by proinflammatory cytokines.
Topics: 3T3 Cells; Animals; Apoptosis; Biopterins; Cell Nucleus; Cell Survival; Curcumin; Cytokines; DNA Fragmentation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; GTP Cyclohydrolase; Hypoxanthines; Interferon-gamma; Interleukin-1; Kinetics; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Osteoblasts; Penicillamine; Proline; Pteridines; Pterins; Recombinant Proteins; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Thiocarbamates; Transcription Factor AP-1; Transcription, Genetic; Transfection; Tumor Necrosis Factor-alpha | 1998 |
An electrogenic amino acid transporter in the apical membrane of cultured human bronchial epithelial cells.
Topics: Alanine; Amiloride; Amino Acid Transport Systems; Amino Acids; Arginine; Bronchi; Carrier Proteins; Cell Membrane; Cells, Cultured; Epithelial Cells; Humans; Kinetics; Lysine; Membrane Potentials; Nitric Oxide Donors; Penicillamine; Proline; S-Nitroso-N-Acetylpenicillamine | 1998 |
The influence of steric interactions on the conformation and biology of oxytocin. Synthesis and analysis of penicillamine(6)-oxytocin and penicillamine(6)-5-tert-butylproline(7)-oxytocin analogs.
Topics: Animals; Female; Molecular Conformation; Oxytocin; Penicillamine; Proline; Rats; Stereoisomerism; Structure-Activity Relationship; Uterus | 2001 |
Enantiomeric reversed-phase high-performance liquid chromatography resolution of D-/L-penicillamine after spirocyclization with ninhydrin and by using copper(II)-L-proline complex as a chiral selector in the mobile phase.
Topics: Chromatography, High Pressure Liquid; Copper; Ninhydrin; Penicillamine; Proline; Spiro Compounds; Stereoisomerism | 2008 |
Intrabodies binding the proline-rich domains of mutant huntingtin increase its turnover and reduce neurotoxicity.
Topics: Animals; Antibodies; Antibody Specificity; Brain; Cell Line, Transformed; Disease Models, Animal; Epitope Mapping; Humans; Huntingtin Protein; Immunoglobulin Variable Region; In Vitro Techniques; Luminescent Proteins; Mutation; Nerve Tissue Proteins; Neurotoxicity Syndromes; Nuclear Proteins; Penicillamine; Peptides; Proline; Protein Binding; Protein Structure, Tertiary; Transfection | 2008 |
Enantioseparations by high-performance liquid chromatography based on chiral ligand-exchange.
Topics: Chromatography, High Pressure Liquid; Cysteine; Hydroxyproline; Ligands; Molecular Structure; Penicillamine; Phenylalanine; Proline; Silica Gel; Stereoisomerism | 2013 |