penicillamine has been researched along with peroxynitric acid in 49 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 39 (79.59) | 18.2507 |
| 2000's | 10 (20.41) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lamarque, D; Whittle, BJ | 2 |
| Darley-Usmar, VM; Feelisch, M; Goodwin, DA; Moncada, S; Moro, MA; Radomski, MW; Read, NG; Zamora-Pino, R | 1 |
| Althaus, JS; Fici, GJ; VonVoigtlander, PF | 1 |
| Hasegawa, T; Katsura, M; Kuriyama, K; Narihara, H; Ohkuma, S | 1 |
| Guo, JL; Hasegawa, T; Katsura, M; Kuriyama, K; Ohkuma, S | 1 |
| Darley-Usmar, VM; Moncada, S; Radomski, MW; Salas, E; Villa, LM | 1 |
| Beckman, J; Crow, JP; Haddad, IY; Hu, P; Matalon, S; Ye, Y | 1 |
| Lenhart, A; Mao, Y; Shi, X | 1 |
| Fréjaville, C; Hogg, N; Kalyanaraman, B; Karoui, H; Tordo, P | 1 |
| Day, BJ; Salzman, AL; Szabó, C | 1 |
| Cassina, A; Radi, R | 1 |
| Hogg, N; Joseph, J; Kalyanaraman, B; Karoui, H | 1 |
| Constantine-Paton, M; Rentería, RC | 1 |
| Halliwell, B; Kaur, H; Whiteman, M | 1 |
| Guo, JL; Hasegawa, T; Katsura, M; Kuriyama, K; Narihara, H; Ohkuma, S | 1 |
| Bolaños, JP; Medina, JM | 1 |
| Schulz, R; Strynadka, KD; Yasmin, W | 1 |
| Clanachan, AS; Dodge, KL; Lopaschuk, GD; Schulz, R | 1 |
| Clark, JE; Foresti, R; Green, CJ; Motterlini, R | 1 |
| Ade, P; Balduzzi, M; Guastadisegni, C; Levi, G; Minghetti, L; Nicolini, A; Polazzi, E | 1 |
| Janssen, YM; Matalon, S; Mossman, BT | 1 |
| Cheung, PY; Danial, H; Jong, J; Schulz, R | 1 |
| Denenberg, AG; Kennedy, M; Salzman, AL; Szabó, C | 1 |
| Ashida, K; Itoh, T; Kamisaki, Y; Kanda, G; Kishimoto, Y; Nakamoto, K; Ohkura, T; Wada, K | 1 |
| Graves, JE; Kooy, NW; Lewis, SJ | 1 |
| Kaminski, PM; Wolin, MS; Xie, YW | 1 |
| Lu, M; Wang, WH | 1 |
| Fukuyama, N; Genka, C; Ishida, H; Nakazawa, H; Su, Z; Todorov, R | 1 |
| Aguirre, DE; Fink, MP; Menconi, MJ; Smith, M; Unno, N | 1 |
| Cantoni, O; Clementi, E; Guidarelli, A; Sciorati, C | 1 |
| Benjamins, JA; Boullerne, AI; Nedelkoska, L | 1 |
| Dweck, HS; Hassan, MS; Mileva, MM; Rosenfeld, L | 1 |
| Hirata, K; Kanazawa, H; Okamoto, T; Shiraishi, S; Yoshikawa, J | 1 |
| Roberts, LJ; van der Veen, RC | 1 |
| Fukuda, J; Kagabu, S; Karube, A; Kodama, H; Murata, M; Tanaka, T | 1 |
| Deeb, RS; Hajjar, DP; Upmacis, RK | 1 |
| Fujita, M; Hotta, Y; Ishikawa, N; Kawai, N; Kohno, M; Liu, W; Masumizu, T; Nakagawa, J; Otsuka-Murakami, H; Yajima, M | 1 |
| Cantoni, O; Clementi, E; Guidarelli, A; Sciorati, C; Sestili, P | 1 |
| Althaus, JS; Hall, ED; Kupina, NC | 1 |
| Hirata, K; Kanazawa, H; Yoshikawa, J | 1 |
| Ju, C; Kim, HC; Kim, WK; Ko, KH; Oh, YK; Ryu, JR; Shin, CY; Yoon, KN | 1 |
| Muriel, P; Sandoval, G | 1 |
| Buckley, BJ; Whorton, AR | 1 |
| Campos-Pérez, JJ; Ellis, AE; Secombes, CJ | 1 |
| Huang, Q; Huang, X; Jin, C; Liu, J; Yang, GY; Zhao, KS | 1 |
| Olsson, LE; Weiss, RM; Wheeler, MA; Yoon, JH | 1 |
| Choi, JW; Kim, H; Kim, W; Ko, KH; Ryu, JH; Ryu, JR; Shin, CY | 1 |
| Hayes, EL; Kanterewicz, BI; Klann, E; Knapp, LT | 1 |
49 other study(ies) available for penicillamine and peroxynitric acid
| Article | Year |
|---|---|
Role of oxygen-derived metabolites in the rat gastric mucosal injury induced by nitric oxide donors.
Topics: Animals; Blood Pressure; Catalase; Deferoxamine; Disease Models, Animal; Drug Overdose; Drug Synergism; Endothelins; Free Radical Scavengers; Gastric Mucosa; Infusions, Intra-Arterial; Infusions, Intravenous; Male; Nitrates; Nitric Oxide; Nitroprusside; Penicillamine; Rats; Rats, Wistar; Reactive Oxygen Species; S-Nitroso-N-Acetylpenicillamine; Stomach Ulcer; Superoxide Dismutase; Thiourea; Vasodilator Agents | 1995 |
Paradoxical fate and biological action of peroxynitrite on human platelets.
Topics: Antigens, CD; Blood Platelets; Cell Adhesion Molecules; Collagen; Epoprostenol; Glutathione; Hemoglobins; Humans; In Vitro Techniques; Indomethacin; Kinetics; Nitrates; Nitroso Compounds; P-Selectin; Penicillamine; Platelet Aggregation; Platelet Membrane Glycoproteins; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione; Serum Albumin; Time Factors; Vasodilator Agents | 1994 |
Antibody transformation by peroxynitrite as determined using capillary electrophoresis: a feasibility study.
Topics: Antibodies; Cyclic AMP; Drug Interactions; Electrophoresis; Feasibility Studies; Nitrates; Penicillamine; Plasminogen Activator Inhibitor 1; Time Factors | 1995 |
Nitric oxide-induced [3H] GABA release from cerebral cortical neurons is mediated by peroxynitrite.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Ceruloplasmin; gamma-Aminobutyric Acid; Mice; Neurons; Nitrates; Nitric Oxide; Nitroprusside; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase; Tritium | 1995 |
Participation of peroxynitrite in acetylcholine release induced by nitric oxide generators.
Topics: Acetylcholine; Animals; Cells, Cultured; Ceruloplasmin; Hemoglobins; Mice; Mice, Inbred Strains; Neurons; Nitrates; Nitric Oxide; Nitroprusside; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase; Superoxides; Vasodilator Agents | 1995 |
Peroxynitrite induces both vasodilatation and impaired vascular relaxation in the isolated perfused rat heart.
Topics: Acetylcholine; Animals; Coronary Circulation; Epoprostenol; Isoproterenol; Male; Nitrates; Nitric Oxide; Penicillamine; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Vasodilation | 1994 |
Concurrent generation of nitric oxide and superoxide damages surfactant protein A.
Topics: Humans; Molsidomine; Nitrates; Nitric Oxide; Oxidation-Reduction; Penicillamine; Proteolipids; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Reactive Oxygen Species; Rhodamines; S-Nitroso-N-Acetylpenicillamine; Superoxides; Time Factors | 1994 |
ESR spin trapping investigation on peroxynitrite decomposition: no evidence for hydroxyl radical production.
Topics: Ascorbic Acid; Cyclic N-Oxides; Cysteine; Electron Spin Resonance Spectroscopy; Formates; Free Radicals; Glutathione; Hydroxyl Radical; Nitrates; Penicillamine; Spin Labels | 1994 |
Characterization of sulfur-centered radical intermediates formed during the oxidation of thiols and sulfite by peroxynitrite. ESR-spin trapping and oxygen uptake studies.
Topics: Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Formates; Free Radicals; Glutathione; Hydroxyl Radical; In Vitro Techniques; Molecular Structure; Nitrates; Oxidation-Reduction; Penicillamine; Spin Labels; Sulfhydryl Compounds; Sulfites | 1996 |
Evaluation of the relative contribution of nitric oxide and peroxynitrite to the suppression of mitochondrial respiration in immunostimulated macrophages using a manganese mesoporphyrin superoxide dismutase mimetic and peroxynitrite scavenger.
Topics: Animals; Aorta, Thoracic; Arginine; Cell Line; Diethylamines; Escherichia coli; Free Radical Scavengers; In Vitro Techniques; Kinetics; Lipopolysaccharides; Macrophages; Manganese; Metalloporphyrins; Mitochondria; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; omega-N-Methylarginine; Oxidation-Reduction; Oxygen Consumption; Penicillamine; Rabbits; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase; Vasodilation | 1996 |
Differential inhibitory action of nitric oxide and peroxynitrite on mitochondrial electron transport.
Topics: Adenosine Triphosphatases; Animals; Dithionite; Electron Transport; Electron Transport Complex IV; Glutathione; Kinetics; Mitochondria, Heart; NADH Dehydrogenase; Nitrates; Nitric Oxide; Nitroso Compounds; Oxygen Consumption; Penicillamine; Rats; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione; Succinate Dehydrogenase; Superoxides | 1996 |
Effect of superoxide dismutase mimics on radical adduct formation during the reaction between peroxynitrite and thiols--an ESR-spin trapping study.
Topics: Cyclic N-Oxides; Cysteine; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Free Radicals; Glutathione; Glutathione Disulfide; Kinetics; Nitrates; Organometallic Compounds; Oxygen; Penicillamine; Spin Labels; Sulfhydryl Compounds; Sulfites; Superoxide Dismutase; Superoxides | 1996 |
Exogenous nitric oxide causes collapse of retinal ganglion cell axonal growth cones in vitro.
Topics: Animals; Axons; Cells, Cultured; Cysteine; Free Radical Scavengers; Mercaptoethanol; Molsidomine; Neurites; Nitrates; Nitric Oxide; Nitrites; Nitroprusside; Nitroso Compounds; Penicillamine; Retinal Ganglion Cells; S-Nitroso-N-Acetylpenicillamine; S-Nitrosothiols; Signal Transduction; Sulfhydryl Reagents; Time Factors; Vasodilator Agents; Xenopus laevis | 1996 |
Protection against peroxynitrite dependent tyrosine nitration and alpha 1-antiproteinase inactivation by some anti-inflammatory drugs and by the antibiotic tetracycline.
Topics: Acetaminophen; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Flufenamic Acid; Free Radical Scavengers; Humans; Mesalamine; Nitrates; Pancreatic Elastase; Penicillamine; Phenylbutazone; Tetracycline; Tyrosine | 1996 |
Role of peroxynitrite in [3H] gamma-aminobutyric acid release evoked by nitric oxide and its mechanism.
Topics: Animals; Cells, Cultured; Ceruloplasmin; Enzyme Inhibitors; gamma-Aminobutyric Acid; Mice; Mice, Inbred Strains; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Nitrates; Nitric Oxide; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Sodium-Potassium-Exchanging ATPase; Superoxide Dismutase | 1996 |
Induction of nitric oxide synthase inhibits gap junction permeability in cultured rat astrocytes.
Topics: Animals; Astrocytes; Cells, Cultured; Enzyme Induction; Fluorescent Dyes; Gap Junctions; Isoquinolines; Lipopolysaccharides; Nitrates; Nitric Oxide Synthase; omega-N-Methylarginine; Penicillamine; Permeability; Rats; Rats, Wistar; Reactive Oxygen Species; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase | 1996 |
Involvement of peroxynitrite in the lipid peroxidation induced by nitric oxide in rat gastric mucosa.
Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gastric Mucosa; Indicators and Reagents; Lipid Peroxidation; Male; Nitrates; Nitric Oxide; Nitroprusside; Penicillamine; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase | 1996 |
Generation of peroxynitrite contributes to ischemia-reperfusion injury in isolated rat hearts.
Topics: Animals; Male; Myocardial Reperfusion Injury; Myocardium; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Penicillamine; Perfusion; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents | 1997 |
Peroxynitrite impairs cardiac contractile function by decreasing cardiac efficiency.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Energy Metabolism; Glucose; Glycolysis; Heart; In Vitro Techniques; Kinetics; Male; Myocardial Contraction; Myocardium; NAD; Nitrates; Oxygen Consumption; Penicillamine; Perfusion; Phosphocreatine; Pyruvates; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine | 1997 |
Thiol compounds interact with nitric oxide in regulating heme oxygenase-1 induction in endothelial cells. Involvement of superoxide and peroxynitrite anions.
Topics: Acetylcysteine; Animals; Aorta; Buthionine Sulfoximine; Cattle; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Enzyme Induction; Glutathione; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Kinetics; Membrane Proteins; Nitrates; Nitric Oxide; Nitrites; Nitroprusside; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Sulfhydryl Compounds; Superoxides; Umbilical Veins | 1997 |
Prostaglandin E2 synthesis is differentially affected by reactive nitrogen intermediates in cultured rat microglia and RAW 264.7 cells.
Topics: Animals; Arachidonic Acid; Cells, Cultured; Cerebral Cortex; Cyclooxygenase 2; Dinoprostone; Enzyme Inhibitors; Isoenzymes; Lipopolysaccharides; Macrophages; Mice; Microglia; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Penicillamine; Prostaglandin-Endoperoxide Synthases; Rats; S-Nitroso-N-Acetylpenicillamine | 1997 |
Differential induction of c-fos, c-jun, and apoptosis in lung epithelial cells exposed to ROS or RNS.
Topics: Animals; Apoptosis; Cell Line; Epithelial Cells; Genes, fos; Genes, jun; Hydrogen Peroxide; Lung; Molsidomine; Nitrates; Nitric Oxide; Penicillamine; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Reactive Oxygen Species; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Spermine; Transcription, Genetic | 1997 |
Thiols protect the inhibition of myocardial aconitase by peroxynitrite.
Topics: Aconitate Hydratase; Animals; Citrates; Cysteine; Dose-Response Relationship, Drug; Drug Interactions; Ferrous Compounds; Glutathione; Glycine; Male; Myocardium; Nitrates; Penicillamine; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Sulfhydryl Compounds | 1998 |
Poly(ADP-ribose) synthetase activation mediates increased permeability induced by peroxynitrite in Caco-2BBe cells.
Topics: Adenosine Triphosphate; Caco-2 Cells; DNA Damage; Humans; Inflammatory Bowel Diseases; Intestinal Mucosa; Molsidomine; Nitrates; Nitric Oxide; Penicillamine; Permeability; Poly(ADP-ribose) Polymerases; S-Nitroso-N-Acetylpenicillamine | 1998 |
Direct measurement of nitric oxide release in gastric mucosa during ischemia-reperfusion in rats.
Topics: Animals; Electrodes; Enzyme Inhibitors; Gastric Mucosa; Ischemia; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Penicillamine; Rats; Rats, Wistar; Regional Blood Flow; Reperfusion; S-Nitroso-N-Acetylpenicillamine; Stomach; Superoxide Dismutase; Superoxides | 1998 |
Peroxynitrite-mediated vasorelaxation: evidence against the formation of circulating S-nitrosothiols.
Topics: Animals; Blood Flow Velocity; Cysteine; Glutathione; Hemodynamics; Male; Mercaptoethanol; Nitrates; Nitroso Compounds; Penicillamine; Rats; Rats, Sprague-Dawley; Regional Blood Flow; S-Nitrosoglutathione; S-Nitrosothiols; Serum Albumin, Bovine; Vasodilation | 1998 |
Inhibition of rat cardiac muscle contraction and mitochondrial respiration by endogenous peroxynitrite formation during posthypoxic reoxygenation.
Topics: Animals; Bradykinin; Cyclic GMP; Free Radical Scavengers; Hydroxyl Radical; Hypoxia; In Vitro Techniques; Kinetics; Mannitol; Mitochondria, Heart; Myocardial Contraction; Nitrates; Nitric Oxide; Nitroarginine; Oxidants; Oxygen Consumption; Penicillamine; Rats; S-Nitroso-N-Acetylpenicillamine; Sodium Cyanide; Superoxide Dismutase | 1998 |
Reaction of nitric oxide with superoxide inhibits basolateral K+ channels in the rat CCD.
Topics: Animals; Cell Membrane; Cyclic GMP; Ditiocarb; In Vitro Techniques; Kidney Cortex; Kidney Tubules, Collecting; Membrane Potentials; Nitrates; Nitric Oxide; Nitroprusside; Patch-Clamp Techniques; Penicillamine; Potassium Channels; Potassium Channels, Calcium-Activated; Pyrogallol; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Small-Conductance Calcium-Activated Potassium Channels; Superoxides | 1998 |
Peroxynitrite is not a major mediator of endothelial cell injury by activated neutrophils in vitro.
Topics: Animals; Antibodies, Monoclonal; Cattle; CD18 Antigens; Cells, Cultured; Coculture Techniques; Deferoxamine; Dimethyl Sulfoxide; Endothelium, Vascular; Humans; Neutrophil Activation; Neutrophils; Nitrates; Nitric Oxide Synthase; Nitrites; Ornithine; Penicillamine; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tyrosine | 1998 |
Nitric oxide donor-induced hyperpermeability of cultured intestinal epithelial monolayers: role of superoxide radical, hydroxyl radical, and peroxynitrite.
Topics: Antioxidants; Caco-2 Cells; Epithelial Cells; Free Radical Scavengers; Glutathione; Humans; Hydroxyl Radical; Intestinal Absorption; Intestines; Kinetics; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Permeability; Superoxide Dismutase; Superoxides | 1998 |
The mechanism of the nitric oxide-mediated enhancement of tert-butylhydroperoxide-induced DNA single strand breakage.
Topics: Caffeine; Calcium; Cytochromes c1; DNA Damage; DNA, Single-Stranded; Electron Transport; Humans; Mitochondria; NAD(P)H Dehydrogenase (Quinone); Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Penicillamine; tert-Butylhydroperoxide; Tumor Cells, Cultured; U937 Cells; Ubiquinone | 1998 |
Synergism of nitric oxide and iron in killing the transformed murine oligodendrocyte cell line N20.1.
Topics: Animals; Cell Death; Cell Line; Coloring Agents; Culture Media, Serum-Free; DNA Fragmentation; Drug Synergism; Immunohistochemistry; Iron; Kinetics; Mice; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Oligodendroglia; Oxidants; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Trypan Blue | 1999 |
Nitric oxide products degrade chondroitin sulfates.
Topics: Chondroitin Sulfates; Chromatography, Gel; Dermatan Sulfate; Glycosaminoglycans; Nitrates; Nitric Oxide; Penicillamine | 1998 |
Inhibition of bronchoprotective effects of beta2-adrenoceptor agonists by peroxynitrite in guinea pig airways.
Topics: Acetylcholine; Adrenergic beta-Agonists; Airway Resistance; Albuterol; Animals; Bronchoconstriction; Colforsin; Guinea Pigs; Isoproterenol; Male; Molsidomine; Nitrates; Penicillamine; Receptors, Adrenergic, beta-1 | 1999 |
Contrasting roles for nitric oxide and peroxynitrite in the peroxidation of myelin lipids.
Topics: Animals; Central Nervous System; Dinoprost; Encephalomyelitis, Autoimmune, Experimental; F2-Isoprostanes; Lipid Peroxidation; Mice; Molsidomine; Myelin Proteins; Myelin Sheath; Nitrates; Nitric Oxide; Nitric Oxide Donors; Oxidants; Penicillamine | 1999 |
Inhibitory effects of nitric oxide on the expression and activity of aromatase in human granulosa cells.
Topics: Adult; Aromatase; Aromatase Inhibitors; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Female; Gene Expression Regulation; Granulosa Cells; Humans; Isoquinolines; Nitrates; Nitric Oxide; Penicillamine; Protein Kinase C; Sodium Nitrite; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1999 |
Regulation of prostaglandin H2 synthase activity by nitrogen oxides.
Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Cells, Cultured; Cyclooxygenase 1; Enzyme Activation; Enzyme Inhibitors; Free Radical Scavengers; Hydrazines; Isoenzymes; Male; Membrane Proteins; Molsidomine; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Penicillamine; Peroxides; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases; Rats; S-Nitroso-N-Acetylpenicillamine; Sheep; Superoxides | 1999 |
Protective role of nitric oxide synthase against ischemia-reperfusion injury in guinea pig myocardial mitochondria.
Topics: Animals; Arginine; Calcium; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Female; Free Radical Scavengers; Free Radicals; Guinea Pigs; Heart; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Immunoblotting; Immunohistochemistry; Male; Mitochondria, Heart; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Penicillamine; Reactive Oxygen Species; Spin Trapping; Superoxide Dismutase | 1999 |
Endogenous and exogenous nitric oxide enhance the DNA strand scission induced by tert-butylhydroperoxide in PC12 cells via peroxynitrite-dependent and independent mechanisms, respectively.
Topics: Animals; Calcium; Chromans; Cyclic N-Oxides; DNA Damage; DNA, Single-Stranded; Electron Transport; Free Radical Scavengers; Imidazoles; Methacrylates; Methionine; Mitochondria; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Donors; Oxidants; PC12 Cells; Penicillamine; Rats; Rotenone; Ruthenium Red; S-Nitroso-N-Acetylpenicillamine; tert-Butylhydroperoxide; Thiazoles | 2000 |
Peroxynitrite scavengers for the acute treatment of traumatic brain injury.
Topics: Animals; Brain Injuries; Chelating Agents; Drug Evaluation, Preclinical; Male; Mice; Nitrates; Penicillamine | 1999 |
Possible mechanism of bronchoprotection by SIN-1 in anaesthetized guinea pigs: roles of nitric oxide and peroxynitrite.
Topics: Acetylcholine; Animals; Bronchi; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchodilator Agents; Dose-Response Relationship, Drug; Glutathione; Guinea Pigs; Male; Molsidomine; Nebulizers and Vaporizers; Nitrates; Nitric Oxide; Penicillamine; Rhodamines; Time Factors; Vasodilator Agents | 2000 |
Synergistic depletion of astrocytic glutathione by glucose deprivation and peroxynitrite: correlation with mitochondrial dysfunction and subsequent cell death.
Topics: Animals; Astrocytes; Cell Survival; Drug Synergism; Glucose; Glutathione; Membrane Potentials; Mitochondria; Molsidomine; Nitrates; Nitric Oxide Donors; Nitroso Compounds; Penicillamine; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione | 2000 |
Nitric oxide and peroxynitrite anion modulate liver plasma membrane fluidity and Na(+)/K(+)-ATPase activity.
Topics: Animals; Cell Fractionation; Cell Polarity; Enzyme Activation; Fluorescence Polarization; Liver; Male; Membrane Fluidity; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase | 2000 |
Adaptive responses to peroxynitrite: increased glutathione levels and cystine uptake in vascular cells.
Topics: Adaptation, Physiological; Animals; Cattle; Cells, Cultured; Cystine; Dose-Response Relationship, Drug; Endothelium, Vascular; Free Radical Scavengers; Glutamic Acid; Glutathione; Metalloporphyrins; Molsidomine; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide Donors; Nucleic Acid Synthesis Inhibitors; Penicillamine; Protein Synthesis Inhibitors; S-Nitroso-N-Acetylpenicillamine; Sodium; Superoxide Dismutase | 2000 |
Toxicity of nitric oxide and peroxynitrite to bacterial pathogens of fish.
Topics: Aeromonas; Animals; Bacterial Infections; Catalase; Cell-Free System; Fish Diseases; Free Radical Scavengers; Microbial Sensitivity Tests; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Oncorhynchus mykiss; Oxidants; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase | 2000 |
Peroxynitrite leads to arteriolar smooth muscle cell membrane hyperpolarization and low vasoreactivity in severe shock.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Animals; Arginine; Arterioles; Charybdotoxin; Cyclic GMP; Drug Interactions; Female; Free Radical Scavengers; Glyburide; Guanidines; Ion Transport; Male; Membrane Potentials; Mesenteric Arteries; Microscopy, Confocal; Microscopy, Fluorescence; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide Donors; Norepinephrine; Oxadiazoles; Penicillamine; Potassium; Potassium Channels; Quinoxalines; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Vasodilator Agents | 2000 |
Cyclooxygenase-2 protein and prostaglandin E(2) production are up-regulated in a rat bladder inflammation model.
Topics: Administration, Intravesical; Animals; Blotting, Western; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Female; Inflammation; Injections, Intraperitoneal; Isoenzymes; Lipopolysaccharides; Membrane Proteins; Niflumic Acid; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Oxidants; Penicillamine; Prostaglandin-Endoperoxide Synthases; Protamines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Up-Regulation; Urinary Bladder | 2001 |
Immunostimulation of rat primary astrocytes decreases intracellular ATP level.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Astrocytes; Central Nervous System; Dose-Response Relationship, Drug; Encephalitis; Enzyme Inhibitors; Inflammation Mediators; Interferon-gamma; Intracellular Fluid; L-Lactate Dehydrogenase; Lipopolysaccharides; Molsidomine; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Penicillamine; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Tumor Cells, Cultured | 2001 |
Peroxynitrite-induced tyrosine nitration and inhibition of protein kinase C.
Topics: Animals; Brain; Cysteine; Isoenzymes; Male; Neurodegenerative Diseases; Nitrates; Nitric Oxide Donors; Nitroprusside; Nitroso Compounds; Oxidants; Oxidation-Reduction; Penicillamine; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Rats; Rats, Sprague-Dawley; S-Nitrosothiols; Tissue Extracts; Tyrosine | 2001 |