penicillamine has been researched along with molsidomine in 139 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 95 (68.35) | 18.2507 |
| 2000's | 41 (29.50) | 29.6817 |
| 2010's | 3 (2.16) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gryglewski, RJ; Salvemini, D; Taylor, GW; Vane, JR; Zembowicz, A | 1 |
| Darley-Usmar, VM; Hogg, N; Moncada, S; O'Leary, VJ; Wilson, MT | 1 |
| Garthwaite, J; Southam, E | 2 |
| Batchelor, AM; East, SJ; Garthwaite, J | 1 |
| Akarid, K; Desforges, B; Gougerot-Pocidalo, MA; Sinet, M | 1 |
| Choi, DW; Csernansky, CA; Hewett, SJ | 1 |
| Shibata, S; Tanaka, T; Watanabe, S; Yamamoto, Y | 1 |
| Furukawa, T; Kohno, H; Taketani, S; Tokunaga, R | 1 |
| Andrew, PJ; Harant, H; Lindley, IJ | 1 |
| Nagy, E; Neumannova, V; Ponka, P; Richardson, DR | 1 |
| Beauvais, F; Dubertret, L; Michel, L | 1 |
| deGroot, H; Hensel, M; Ioannidis, I; Kox, WJ; Volk, T | 1 |
| Bialecki, RA; Stinson-Fisher, C | 1 |
| Meffert, MK; Premack, BA; Schulman, H | 1 |
| Cunningham, JM; Delaney, CA; Green, IC; Mabley, JG | 1 |
| Beckman, J; Crow, JP; Haddad, IY; Hu, P; Matalon, S; Ye, Y | 1 |
| Ceppi, ED; Horton, RA; Knowles, RG; Titheradge, MA | 1 |
| de Groot, H; Ioannidis, I | 1 |
| Darley-Usmar, VM; Hogg, N; Moncada, S; Wilson, MT | 1 |
| Brenner, HH; Etzkorn, K; Kolb, H; Kolb-Bachofen, V; Kröncke, KD; Noack, EA; Rodriguez, ML | 1 |
| Kankaanranta, H; Metsä-Ketelä, T; Moilanen, E; Vapaatalo, H; Vuorinen, P | 1 |
| Galluser, M; Raul, F; Schleiffer, R | 1 |
| Chaudhuri, G; Chopra, M; Gryglewski, R; Ignarro, LJ; Radziszewski, W; Zembowicz, A | 1 |
| Brien, JF; Jimmo, SL; Marks, GS; McLaughlin, BE; Nakatsu, K; Poklewska-Koziell, M | 1 |
| Dikshit, M; Shukla, A; Srimal, RC | 1 |
| Lapetina, EG; Reep, BR | 1 |
| Currie, MG; Mollace, V; Salvemini, D | 1 |
| Brutsaert, DL; Mohan, P; Paulus, WJ; Sys, SU | 1 |
| Constantine-Paton, M; Rentería, RC | 1 |
| Behar-Cohen, FF; Courtois, Y; D'Hermies, F; Goureau, O | 1 |
| Kawanishi, M | 1 |
| Palluy, O; Rigaud, M | 1 |
| Irifune, M; Kamata, Y; Nishikawa, T; Sato, T | 1 |
| Barefield, E; Crow, J; Gadilhe, T; Haddad, IY; Matalon, S; Zhu, S | 1 |
| Foresti, R; Intaglietta, M; Motterlini, R; Winslow, RM | 1 |
| Garcia-Dorado, D; Jakob, G; Piper, HM; Ruiz-Meana, M; Schlüter, KD | 1 |
| Fandrey, J; Hoffmann, G; Schobersberger, W | 1 |
| Pehl, U; Schmid, HA | 1 |
| Ebihara, Y; Karmazyn, M | 1 |
| Grisham, MB; Milligan, SA; Owens, MW | 1 |
| Kapás, L; Krueger, JM | 1 |
| Sontheimer, H; Ye, ZC | 1 |
| Adler, KB; Akley, NJ; Fischer, BM; Li, C; Rochelle, LG; Wright, DT | 1 |
| Damoulis, PD; Hauschka, PV | 1 |
| Christodoulides, N; Durante, W; Kroll, MH; Peyton, KJ; Schafer, AI | 1 |
| Bauer, H; Frölich, JC; Jung, T; Neumann, C; Stichtenoth, DO; Tsikas, D | 1 |
| Iadecola, C; Yang, G | 1 |
| Brady, T; D'Ambrosio, SM; Oberyszyn, TM; Robertson, FM; Ross, MS | 1 |
| Fandrey, J; Kiprianova, I; Schwab, S; Spranger, M | 1 |
| Dietl, P; Friedrich, F; Hoffmann, G; Schobersberger, W; Völkl, H | 1 |
| Boscá, L; Dallaporta, B; Hirsch, T; Hortelano, S; Kroemer, G; Marzo, I; Susin, SA; Zamzami, N | 1 |
| Behrendt, J; Beste, O; Dittrich, K; Dötsch, J; Hänze, J; Rascher, W; Weber, WM | 1 |
| Ade, P; Balduzzi, M; Guastadisegni, C; Levi, G; Minghetti, L; Nicolini, A; Polazzi, E | 1 |
| Brorson, JR; Zhang, H | 1 |
| D'Souza, SW; Lees, RD; Slater, P | 1 |
| Janssen, YM; Matalon, S; Mossman, BT | 1 |
| Bhatnagar, A; Chandra, A; Petrash, JM; Srivastava, S; Srivastava, SK | 1 |
| Billiar, TR; Kim, YM; Li, J; Talanian, RV | 1 |
| Cullen, VC; Eustace, NP; Keenan, AK | 1 |
| Gryglewski, RJ; Marcinkiewicz, E; Michalska, Z; Robak, J | 1 |
| Nishio, E; Watanabe, Y | 1 |
| Demontis, MP; Emanueli, C; Madeddu, P; Varoni, MV; Volpe, AR | 1 |
| Chang, ES; Graubard, K; Scholz, NL; Truman, JW | 1 |
| Denenberg, AG; Kennedy, M; Salzman, AL; Szabó, C | 1 |
| Gauer, S; Pröls, F; Schoecklmann, HO; Sterzel, RB; Yao, J | 1 |
| Hagino, Y; Matsui, S; Nomura, H; Nomura, T; Ohtsuki, M; Sumi-Ichinose, C | 1 |
| Elmedal, B; Hernández, M; Mulvany, MJ; Simonsen, U | 1 |
| Akita, H; Hirata, K; Kawashima, S; Rikitake, Y; Yokoyama, M | 1 |
| Cohen, RA; Garland, CJ; Jeremy, JY; Plane, F; Wiley, KE | 1 |
| Lee, EH; Tsai, MJ | 1 |
| Holm, P; Kankaanranta, H; Metsä-Ketelä, T; Moilanen, E | 1 |
| Ahmed, U; Conant, K; Major, EO; Schwartz, JP | 1 |
| Bernassola, F; Catani, MV; Melino, G; Rossi, A | 1 |
| Feelisch, M | 1 |
| Bocca, AL; Campanelli, AP; Cunha, FQ; Figueiredo, F; Furlanetto, AB; Hayashi, EE; Pinheiro, AG | 1 |
| Lähteenmäki, T; Sievi, E; Vapaatalo, H | 1 |
| Aguirre, DE; Fink, MP; Menconi, MJ; Smith, M; Unno, N | 1 |
| Keilhoff, G; Reiser, M; Schild, L; Wolf, G | 1 |
| Aizenman, E; Potthoff, WK | 1 |
| Buus, NH; Mulvany, MJ; Simonsen, U; Wadsworth, RM | 1 |
| Hirata, K; Kanazawa, H; Okamoto, T; Shiraishi, S; Yoshikawa, J | 1 |
| Hatori, M; Kamijo, R; Nagumo, M; Sumitani, K; Takizawa, K; Toyoshima, T | 1 |
| Archer, DC; Blantz, RC; Ishizuka, S; Kelly, CJ; Satriano, J | 1 |
| Roberts, LJ; van der Veen, RC | 1 |
| Choi, JJ; Kim, WK; Ko, KH; Seo, DO | 1 |
| Chesnais, JM; Fischmeister, R; Méry, PF | 1 |
| Immenschuh, S; Iwahara, S; Ramadori, G; Stritzke, J | 1 |
| Kim, HS; Kim, SH; Son, YR | 1 |
| Lenzen, S; Lortz, S; Munday, R; Tiedge, M | 1 |
| Chénais, B; Jeannesson, P; Molle, I | 1 |
| Iwase, M; Nagumo, M; Ohashi, M | 1 |
| Deeb, RS; Hajjar, DP; Upmacis, RK | 1 |
| Campagnolo, C; Claveau, D; Li, C; Ouellet, M; Percival, MD | 1 |
| Balduzzi, M; Guastadisegni, C; Levi, G; Minghetti, L; Nicolini, A; Polazzi, E | 1 |
| Hirata, K; Kanazawa, H; Yoshikawa, J | 1 |
| Cox, G; Janssen, LJ; Keshavjee, S; Lu-Chao, H; Premji, M | 1 |
| Ju, C; Kim, HC; Kim, WK; Ko, KH; Oh, YK; Ryu, JR; Shin, CY; Yoon, KN | 1 |
| Abate, A; Dennery, PA; Polte, T; Schröder, H | 1 |
| Benhamou, PY; Kerr-Conte, J; Lemarchand, P; Moriscot, C; Pattou, F; Richard, MJ | 1 |
| Komarov, AM; Mak, IT; Weglicki, WB | 1 |
| Chen, JW; Eatock, RA | 1 |
| Nieland, LJ; Ramaekers, FC; Reutelingsperger, CP; Schutte, B; Steinbusch, HW; Terwel, D | 1 |
| Cai, L; Ingram, AJ; James, L; Ly, H; Scholey, JW; Thai, K | 1 |
| Muriel, P; Sandoval, G | 1 |
| Buckley, BJ; Whorton, AR | 1 |
| Andersson, RG; Glindell, M; Jacobsson-Strier, M; Nyhlén, K; Persson, K; Whiss, PA | 1 |
| Marthan, R; Pauvert, O; Savineau, J | 1 |
| Jensen, MS; Nyborg, NC; Thomsen, ES | 1 |
| Bernardet, N; Dambrine, G; Djeraba, A; Quéré, P | 1 |
| Campos-Pérez, JJ; Ellis, AE; Secombes, CJ | 1 |
| Brady, T; D'Ambrosio, SM; Gibson-D'Ambrosio, RE; Oberyszyn, AS; Robertson, FM | 1 |
| Flores, A; Soto, E; Vega, R | 1 |
| Decking, UK; Schrader, J; Stumpe, T | 1 |
| Ascenzi, P; Colasanti, M; Gradoni, L; Mattu, M; Salvati, L; Scalone, A; Venturini, G | 1 |
| Choi, JW; Kim, H; Kim, W; Ko, KH; Ryu, JH; Ryu, JR; Shin, CY | 1 |
| Buxton, IL; Kaiser, RA; Malmquist, NA; Tichenor, S | 1 |
| Cooke, JP; Dulak, J; Funovics, P; Guevara, I; Huk, I; Jozkowicz, A; Pachinger, O; Weidinger, F | 1 |
| Hewett, JA; Hewett, SJ; Uliasz, TF; Vidwans, AS | 1 |
| Assreuy, J; Sampaio de Freitas, M; Santos-Silva, MC | 1 |
| Droogmans, G; Nilius, B; Suh, SH; Watanabe, H | 1 |
| Esumi, H; Kimura, H; Kurashima, Y; Ogura, T; Weisz, A | 1 |
| Laude, K; Richard, V; Thuillez, C | 1 |
| Assreuy, J; Costa, RS | 1 |
| Iida, H; Inoue, N; Ishida, H; Ishikawa, Y; Yuan, Z | 1 |
| Beltrán, A; González, D; Herrera, B; Otero, K; Quintero, G; Rojas, A | 1 |
| Antunes, E; De Nucci, G; Marcondes, S; Moreira, J; Thomazzi, SM | 1 |
| Kim, KH; Kim, SK; Kim, SM; Kwon, SR; Lee, EH; Nam, YK | 1 |
| Adapala, NS; Chan, MM; Fong, D | 1 |
| Abiru, S; Eguchi, K; Ishibashi, H; Komori, A; Maeda, Y; Migita, K; Nakamura, M; Takii, Y; Yatsuhashi, H; Yokoyama, T | 1 |
| Bar-Shai, M; Reznick, AZ | 1 |
| Dirnagl, U; Dreier, JP; Lindauer, U; Scheckenbach, KE | 1 |
| Bar-Shai, M; Hasnis, E; Reznick, AZ; Wiener-Megnazi, Z | 1 |
| Hall, ED; Singh, IN; Sullivan, PG | 1 |
| Croons, V; De Meyer, GR; Herman, AG; Martinet, W; Timmermans, JP | 1 |
| Greenberg, DA; Jin, K; Khan, AA; Mao, XO; Xie, L | 1 |
| Badejo, AM; Bhartiya, M; Bueno, FR; Casey, DB; Kadowitz, PJ; Murthy, SN; Nossaman, BD; Pankey, EA; Uppu, RM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
1 review(s) available for penicillamine and molsidomine
| Article | Year |
|---|---|
The use of nitric oxide donors in pharmacological studies.
Topics: Animals; Glutathione; Humans; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Nitroso Compounds; Penicillamine; S-Nitrosoglutathione | 1998 |
138 other study(ies) available for penicillamine and molsidomine
| Article | Year |
|---|---|
Modulation of the pharmacological actions of nitrovasodilators by methylene blue and pyocyanin.
Topics: Animals; Aorta; Cyclic GMP; Drug Interactions; In Vitro Techniques; Methylene Blue; Molsidomine; Nitric Oxide; Nitroglycerin; Nitroprusside; Penicillamine; Platelet Aggregation; Pyocyanine; Rabbits; S-Nitroso-N-Acetylpenicillamine; Sodium Nitrite; Vasodilator Agents | 1992 |
The simultaneous generation of superoxide and nitric oxide can initiate lipid peroxidation in human low density lipoprotein.
Topics: Antioxidants; Catalase; Humans; Lipid Peroxidation; Lipoproteins, LDL; Molecular Structure; Molsidomine; Nitric Oxide; Nitroprusside; Oxygen Consumption; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase; Superoxides; Time Factors | 1992 |
Comparative effects of some nitric oxide donors on cyclic GMP levels in rat cerebellar slices.
Topics: Animals; Cerebellum; Cyclic GMP; Hydroxylamine; Hydroxylamines; In Vitro Techniques; Molsidomine; Nitric Oxide; Nitroprusside; Penicillamine; Rats; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents | 1991 |
Intercellular action of nitric oxide in adult rat cerebellar slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebellum; Cyclic GMP; Drug Interactions; Glutamates; Glutamic Acid; Hemoglobins; Hydroxylamine; Hydroxylamines; Ibotenic Acid; Kainic Acid; Molsidomine; N-Methylaspartate; Nitric Oxide; Nitroprusside; Penicillamine; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; S-Nitroso-N-Acetylpenicillamine | 1991 |
Selective blockade of N-methyl-D-aspartate receptor function by the nitric oxide donor, nitroprusside.
Topics: Action Potentials; Animals; Cerebellum; Glutamates; Glutamic Acid; Molsidomine; N-Methylaspartate; Nitric Oxide; Nitroprusside; Penicillamine; Rats; Receptors, N-Methyl-D-Aspartate; S-Nitroso-N-Acetylpenicillamine; Stimulation, Chemical; Synapses | 1991 |
Inhibitory effect of nitric oxide on the replication of a murine retrovirus in vitro and in vivo.
Topics: Animals; Antiviral Agents; Arginine; Cell Line; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblasts; Friend murine leukemia virus; Kinetics; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Mice, Inbred DBA; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Sodium Nitrite; Virus Replication | 1995 |
Selective potentiation of NMDA-induced neuronal injury following induction of astrocytic iNOS.
Topics: Amino Acid Oxidoreductases; Animals; Astrocytes; Cell Death; Cells, Cultured; Drug Synergism; Enzyme Induction; In Vitro Techniques; Interferon-gamma; Interleukin-1; Kainic Acid; Mice; Molsidomine; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Synthase; Penicillamine; S-Nitroso-N-Acetylpenicillamine | 1994 |
NG-nitro-L-arginine protects against hypoxia/hypoglycemia-induced decrease in CA1 presynaptic spikes in rat hippocampal slices.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Electrophysiology; Hippocampus; Hypoglycemia; Hypoxia, Brain; In Vitro Techniques; Male; Molsidomine; Nerve Fibers; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Penicillamine; Quinoxalines; Rats; Rats, Wistar; Receptors, Presynaptic; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents | 1995 |
Nitric oxide-mediated inactivation of mammalian ferrochelatase in vivo and in vitro: possible involvement of the iron-sulphur cluster of the enzyme.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Cloning, Molecular; Enzyme Inhibitors; Escherichia coli; Ferrochelatase; Humans; Immunoblotting; Interferon-gamma; Iron-Sulfur Proteins; Lipopolysaccharides; Macrophages; Mammals; Mice; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Penicillamine; Recombinant Proteins; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents | 1995 |
Nitric oxide regulates IL-8 expression in melanoma cells at the transcriptional level.
Topics: Base Sequence; Binding Sites; CCAAT-Enhancer-Binding Proteins; Cell Line; DNA Primers; DNA-Binding Proteins; Gene Expression; Glutathione; Humans; Interleukin-8; Melanoma; Molecular Sequence Data; Molsidomine; Mutagenesis, Site-Directed; NF-kappa B; Nitric Oxide; Nitroso Compounds; Nuclear Proteins; Penicillamine; Platelet Aggregation Inhibitors; Polymerase Chain Reaction; Promoter Regions, Genetic; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured; Vasodilator Agents | 1995 |
The effect of redox-related species of nitrogen monoxide on transferrin and iron uptake and cellular proliferation of erythroleukemia (K562) cells.
Topics: Antioxidants; Biological Transport; Cell Division; Gene Expression Regulation, Leukemic; Humans; Iron; Iron-Regulatory Proteins; Leukemia, Erythroblastic, Acute; Macromolecular Substances; Models, Biological; Molsidomine; Neoplasm Proteins; Nitric Oxide; Nitroprusside; Oxidation-Reduction; Penicillamine; Protein Binding; Protein Processing, Post-Translational; Receptors, Transferrin; RNA Processing, Post-Transcriptional; RNA-Binding Proteins; RNA, Messenger; RNA, Neoplasm; S-Nitroso-N-Acetylpenicillamine; Sulfhydryl Compounds; Transferrin; Tumor Cells, Cultured; Up-Regulation | 1995 |
Exogenous nitric oxide elicits chemotaxis of neutrophils in vitro.
Topics: Aminoquinolines; Cells, Cultured; Chemotactic Factors; Chemotaxis, Leukocyte; Cysteine; Enzyme Inhibitors; Guanylate Cyclase; Humans; Molsidomine; Neutrophils; Nitric Oxide; Penicillamine; S-Nitroso-N-Acetylpenicillamine; S-Nitrosothiols | 1995 |
Endothelial damage induced by nitric oxide: synergism with reactive oxygen species.
Topics: Analysis of Variance; Animals; Antimycin A; Catalase; Cells, Cultured; Endothelium; Kinetics; Liver; Molsidomine; Nitric Oxide; Nitroprusside; Penicillamine; Potassium Cyanide; Rats; Reactive Oxygen Species; Rotenone; S-Nitroso-N-Acetylpenicillamine; Time Factors; Vasodilator Agents | 1995 |
KCa channel antagonists reduce NO donor-mediated relaxation of vascular and tracheal smooth muscle.
Topics: Animals; Calcium; Cyclic GMP; Guinea Pigs; In Vitro Techniques; Male; Molsidomine; Muscle Relaxation; Muscle, Smooth; Muscle, Smooth, Vascular; Nitric Oxide; Penicillamine; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Trachea | 1995 |
Nitric oxide stimulates Ca(2+)-independent synaptic vesicle release.
Topics: Animals; Calcium; Fluorescent Dyes; Glutamates; Glutamic Acid; Hippocampus; Indoles; Kinetics; Male; Molsidomine; Nitric Oxide; Nitroprusside; Penicillamine; Potassium Chloride; Pyridinium Compounds; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Sodium Nitrite; Spectrometry, Fluorescence; Synaptic Vesicles; Vasodilator Agents | 1994 |
The effect of nitric oxide donors on insulin secretion, cyclic GMP and cyclic AMP in rat islets of Langerhans and the insulin-secreting cell lines HIT-T15 and RINm5F.
Topics: Animals; Cell Line; Cyclic AMP; Cyclic GMP; Drug Interactions; Female; Glutathione; Hydroxylamine; Hydroxylamines; Insulin; Insulin Secretion; Islets of Langerhans; Molsidomine; Nitric Oxide; Nitroso Compounds; Penicillamine; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione | 1994 |
Concurrent generation of nitric oxide and superoxide damages surfactant protein A.
Topics: Humans; Molsidomine; Nitrates; Nitric Oxide; Oxidation-Reduction; Penicillamine; Proteolipids; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Reactive Oxygen Species; Rhodamines; S-Nitroso-N-Acetylpenicillamine; Superoxides; Time Factors | 1994 |
Inhibition of hepatic gluconeogenesis by nitric oxide: a comparison with endotoxic shock.
Topics: Animals; Dihydroxyacetone; Endotoxins; Fructose; Gluconeogenesis; Glycerol; Lactates; Liver; Male; Molsidomine; Nitric Oxide; Nitrites; Penicillamine; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Shock, Septic | 1994 |
Cytotoxicity of nitric oxide in Fu5 rat hepatoma cells: evidence for co-operative action with hydrogen peroxide.
Topics: Animals; Carcinoma, Hepatocellular; Catalase; Cell Line; Cell Survival; Glucose Oxidase; Hydrogen Peroxide; Kinetics; Liver Neoplasms; Molsidomine; Nitric Oxide; Nitroprusside; Penicillamine; Rats; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase; Superoxides; Tumor Cells, Cultured; Vasodilator Agents; Xanthine Oxidase | 1993 |
The oxidation of alpha-tocopherol in human low-density lipoprotein by the simultaneous generation of superoxide and nitric oxide.
Topics: Acetaldehyde; Catalase; Free Radicals; Humans; Hydroxides; Hydroxyl Radical; Lipoproteins, LDL; Molsidomine; Nitric Oxide; Nitrogen Dioxide; Oxidation-Reduction; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase; Superoxides; Thiobarbiturates; Vitamin E; Xanthine Oxidase | 1993 |
Pancreatic islet cells are highly susceptible towards the cytotoxic effects of chemically generated nitric oxide.
Topics: Animals; Cells, Cultured; Female; Islets of Langerhans; Male; Mice; Molsidomine; Nitric Oxide; Nitroprusside; Penicillamine; Rats; Rats, Inbred Lew; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Superoxides; Trypan Blue; Tumor Cells, Cultured | 1993 |
Inhibition by nitric oxide-donors of human polymorphonuclear leucocyte functions.
Topics: Cell Degranulation; Chemotaxis, Leukocyte; Cyclic AMP; Cyclic GMP; Glucuronidase; Humans; In Vitro Techniques; Leukotriene B4; Luminescent Measurements; Molsidomine; Neutrophils; Nitric Oxide; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Superoxides; Triazoles | 1993 |
Intestinal absorption of calcium in vivo is dependent on endogenous nitric oxide.
Topics: Animals; Arginine; Calcium; Female; Intestinal Absorption; Intestine, Small; Male; Mesenteric Veins; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Penicillamine; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents | 1995 |
Nitric oxide donors induce extrusion of cyclic GMP from isolated human blood platelets by a mechanism which may be modulated by prostaglandins.
Topics: 1-Methyl-3-isobutylxanthine; Blood Platelets; Cells, Cultured; Culture Media; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Space; Guanylate Cyclase; Humans; Ion Transport; Molsidomine; Nitric Oxide; Ouabain; Penicillamine; Phosphodiesterase Inhibitors; Platelet Aggregation Inhibitors; Probenecid; Prostaglandin D2; Prostaglandins; Prostaglandins A; Purinones; S-Nitroso-N-Acetylpenicillamine; Sodium-Potassium-Exchanging ATPase; Time Factors; Triazoles | 1995 |
Time-dependent increase in nitric oxide formation concurrent with vasodilation induced by sodium nitroprusside, 3-morpholinosydnonimine, and S-nitroso-N-acetylpenicillamine but not by glyceryl trinitrate.
Topics: Animals; Aorta, Thoracic; In Vitro Techniques; Luminescent Measurements; Male; Molsidomine; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitroglycerin; Nitroprusside; Penicillamine; Rabbits; S-Nitroso-N-Acetylpenicillamine; Time Factors; Vasodilation; Vasodilator Agents | 1995 |
Nitric oxide-dependent blood-brain barrier permeability alteration in the rat brain.
Topics: Animals; Arginine; Atropine; Blood Pressure; Blood-Brain Barrier; Heart Rate; Kinetics; Microcirculation; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Penicillamine; Permeability; Rats; Rats, Sprague-Dawley; Reference Values; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents | 1996 |
Nitric oxide stimulates the phosphorylation of rap1b in human platelets and acts synergistically with iloprost.
Topics: Blood Platelets; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Humans; Iloprost; Kinetics; Molsidomine; Nitric Oxide; Penicillamine; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; rap GTP-Binding Proteins; S-Nitroso-N-Acetylpenicillamine | 1996 |
Nitric oxide-mediated cyclooxygenase activation. A key event in the antiplatelet effects of nitrovasodilators.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Animals; Aorta; Cattle; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Epoprostenol; Hemoglobins; Humans; Kinetics; Male; Methylene Blue; Models, Cardiovascular; Molsidomine; Nitric Oxide; Nitroglycerin; Nitroprusside; Penicillamine; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Vasodilation; Vasodilator Agents; Verapamil | 1996 |
Myocardial contractile response to nitric oxide and cGMP.
Topics: Animals; Cats; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Molsidomine; Myocardial Contraction; Nitric Oxide; Nitroprusside; Penicillamine; Purinones; S-Nitroso-N-Acetylpenicillamine | 1996 |
Exogenous nitric oxide causes collapse of retinal ganglion cell axonal growth cones in vitro.
Topics: Animals; Axons; Cells, Cultured; Cysteine; Free Radical Scavengers; Mercaptoethanol; Molsidomine; Neurites; Nitrates; Nitric Oxide; Nitrites; Nitroprusside; Nitroso Compounds; Penicillamine; Retinal Ganglion Cells; S-Nitroso-N-Acetylpenicillamine; S-Nitrosothiols; Signal Transduction; Sulfhydryl Reagents; Time Factors; Vasodilator Agents; Xenopus laevis | 1996 |
Decreased intraocular pressure induced by nitric oxide donors is correlated to nitrite production in the rabbit eye.
Topics: Acetonitriles; Animals; Aqueous Humor; Eye; Eye Proteins; Female; Injections; Intraocular Pressure; Molsidomine; Morpholines; Nitric Oxide; Nitrites; Ocular Hypotension; Penicillamine; Rabbits; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents; Vitreous Body | 1996 |
Nitric oxide inhibits Epstein-Barr virus DNA replication and activation of latent EBV.
Topics: Blotting, Northern; Blotting, Southern; DNA Replication; Herpesvirus 4, Human; Molsidomine; Nitric Oxide; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Viral Proteins; Virus Latency; Virus Replication | 1995 |
Nitric oxide induces cultured cortical neuron apoptosis.
Topics: Animals; Apoptosis; Cells, Cultured; Cerebral Cortex; DNA; Electrophoresis, Agar Gel; Glutathione; Molsidomine; Nerve Tissue Proteins; Neurons; Nitric Oxide; Nitroso Compounds; Penicillamine; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione | 1996 |
Inhibition of purified (Na+,K+)-ATPase activity from porcine cerebral cortex by NO generating drugs.
Topics: Animals; Cerebral Cortex; Dithiothreitol; Enzyme Inhibitors; Molsidomine; Nitric Oxide; Nitro Compounds; Nitroprusside; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Sodium-Potassium-Exchanging ATPase; Sulfhydryl Reagents; Superoxide Dismutase; Swine | 1995 |
Inhibition of alveolar type II cell ATP and surfactant synthesis by nitric oxide.
Topics: Adenosine Triphosphate; Administration, Inhalation; Animals; Cells, Cultured; Molsidomine; Nitric Oxide; Nitrogen Oxides; Penicillamine; Pulmonary Alveoli; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Spermine | 1996 |
NO-mediated activation of heme oxygenase: endogenous cytoprotection against oxidative stress to endothelium.
Topics: Animals; Bilirubin; Cell Line; Cell Survival; Endothelium, Vascular; Enzyme Activation; Enzyme Induction; Heme Oxygenase (Decyclizing); Hydrogen Peroxide; Male; Molsidomine; Nitric Oxide; Nitrites; Nitroprusside; Oxidative Stress; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Swine | 1996 |
Protection of reoxygenated cardiomyocytes against osmotic fragility by nitric oxide donors.
Topics: Animals; Antioxidants; Diacetyl; Enzyme Activation; Guanylate Cyclase; Hypoxia; Male; Molsidomine; Myocardium; Nitric Oxide; Nitroprusside; Osmotic Fragility; Oxygen; Penicillamine; Phenylenediamines; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine | 1996 |
Nitric oxide donors suppress erythropoietin production in vitro.
Topics: Carcinoma, Hepatocellular; Cyclic GMP; Cytokines; Erythropoietin; Humans; Hydrogen Peroxide; Liver Neoplasms; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Penicillamine; Reactive Oxygen Species; S-Nitroso-N-Acetylpenicillamine; Tumor Cells, Cultured | 1996 |
Regional specific effects of nitric oxide donors and cGMP on the electrical activity of neurons in the rat spinal cord.
Topics: Animals; Cyclic GMP; Dose-Response Relationship, Drug; Electrophysiology; Enzyme Inhibitors; Histocytochemistry; Male; Molsidomine; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Organ Culture Techniques; Penicillamine; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Spinal Cord; Vasodilator Agents | 1996 |
Inhibition of beta- but not alpha 1-mediated adrenergic responses in isolated hearts and cardiomyocytes by nitric oxide and 8-bromo cyclic GMP.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Calcium; Cell Size; Cells, Cultured; Cyclic GMP; Isoproterenol; Male; Molsidomine; Myocardial Contraction; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Penicillamine; Perfusion; Phenylephrine; Propranolol; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Stimulation, Chemical; Vasodilator Agents | 1996 |
Inhibition of pleural mesothelial cell collagen synthesis by nitric oxide.
Topics: Animals; Cell Line; Collagen; Cytokines; Epithelial Cells; Epithelium; Free Radicals; Inflammation Mediators; Lipopolysaccharides; Molsidomine; Nitric Oxide; Penicillamine; Pleura; Rats; S-Nitroso-N-Acetylpenicillamine | 1996 |
Nitric oxide donors SIN-1 and SNAP promote nonrapid-eye-movement sleep in rats.
Topics: Animals; Body Temperature; Electroencephalography; Enzyme Inhibitors; Male; Molsidomine; Motor Activity; Nitric Oxide; Penicillamine; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Sleep; Sodium-Potassium-Exchanging ATPase | 1996 |
Cytokine modulation of glial glutamate uptake: a possible involvement of nitric oxide.
Topics: Animals; Animals, Newborn; Biological Transport; Cells, Cultured; Cytokines; Enzyme Inhibitors; Glutamic Acid; Hippocampus; Humans; Interferon-gamma; Interleukin-1; Kinetics; Molsidomine; Neuroglia; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Penicillamine; Rats; Rats, Sprague-Dawley; Recombinant Proteins; S-Nitroso-N-Acetylpenicillamine; Tumor Necrosis Factor-alpha | 1996 |
Oxidant stress stimulates mucin secretion and PLC in airway epithelium via a nitric oxide-dependent mechanism.
Topics: Animals; Cell Transformation, Viral; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Epithelium; Guinea Pigs; Humans; Hydrogen Peroxide; Molsidomine; Mucins; Nitric Oxide; omega-N-Methylarginine; Penicillamine; Peroxides; Reactive Oxygen Species; S-Nitroso-N-Acetylpenicillamine; Superoxides; tert-Butylhydroperoxide; Trachea; Type C Phospholipases; Xanthine Oxidase | 1996 |
Nitric oxide acts in conjunction with proinflammatory cytokines to promote cell death in osteoblasts.
Topics: Animals; Bone Remodeling; Cell Death; Cell Line; Coculture Techniques; Glutathione; Hormones; Humans; Interferon-gamma; Interleukin-1; Mice; Molsidomine; Nitric Oxide; Nitroso Compounds; Osteoblasts; Penicillamine; Recombinant Proteins; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione; Tumor Necrosis Factor-alpha | 1997 |
Nitric oxide induces heme oxygenase-1 gene expression and carbon monoxide production in vascular smooth muscle cells.
Topics: Animals; Carbon Monoxide; Cells, Cultured; Cyclic GMP; Cycloheximide; Cytokines; Dactinomycin; Enzyme Inhibitors; Gene Expression Regulation; Heme Oxygenase (Decyclizing); Molsidomine; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; Penicillamine; Rats; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Time Factors; Transcription, Genetic | 1997 |
Nitric oxide inhibits the secretion of T-helper 1- and T-helper 2-associated cytokines in activated human T cells.
Topics: CD3 Complex; Cell Culture Techniques; Cell Division; Cytokines; Humans; Lymphocyte Activation; Molsidomine; Nitric Oxide; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Th1 Cells; Th2 Cells | 1997 |
Obligatory role of NO in glutamate-dependent hyperemia evoked from cerebellar parallel fibers.
Topics: Animals; Blood Pressure; Carbon Dioxide; Cerebellum; Cyclic GMP; Electric Stimulation; Enzyme Inhibitors; Glutamic Acid; Hyperemia; Indazoles; Male; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oxygen; Papaverine; Partial Pressure; Penicillamine; Rats; Rats, Sprague-Dawley; Regional Blood Flow; S-Nitroso-N-Acetylpenicillamine; Vasodilation | 1997 |
Sensitivity of human hepatocytes in culture to reactive nitrogen intermediates.
Topics: Cells, Cultured; Enzyme Inhibitors; Humans; In Vitro Techniques; Liver; Molsidomine; Nitrites; Nitrogen; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Sodium-Potassium-Exchanging ATPase; Tyrosine | 1997 |
Suppression of the oxidative burst in murine microglia by nitric oxide.
Topics: Animals; Animals, Newborn; Cell Survival; Cells, Cultured; Enzyme Inhibitors; Interferon-gamma; Interleukin-1; Kinetics; Luminescent Measurements; Mice; Microglia; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Penicillamine; Respiratory Burst; S-Nitroso-N-Acetylpenicillamine; Superoxides | 1997 |
Nitric oxide donors inhibit spontaneous depolarizations by L-type Ca2+ currents in alveolar epithelial cells.
Topics: Aminoquinolines; Animals; Calcium Channels; Calcium Channels, L-Type; Cell Line; Cyclic GMP; Enzyme Inhibitors; Epithelium; Guanylate Cyclase; Kinetics; Membrane Potentials; Microelectrodes; Molsidomine; Nitroprusside; Penicillamine; Pulmonary Alveoli; Rats; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Strontium; Time Factors | 1997 |
Nitric oxide induces apoptosis via triggering mitochondrial permeability transition.
Topics: Animals; Apoptosis; Cells, Cultured; Glutathione; Intracellular Membranes; Membrane Potentials; Mice; Mice, Inbred BALB C; Mitochondria, Liver; Molsidomine; Nitric Oxide; Nitroso Compounds; Penicillamine; Permeability; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione; Thymus Gland | 1997 |
Suppression of neuropeptide Y1 receptor function in SK-N-MC cells by nitric oxide.
Topics: Blotting, Northern; Cyclic AMP; Molsidomine; Nitric Oxide; Nitroprusside; Penicillamine; Receptors, Neuropeptide Y; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Tumor Cells, Cultured; Vasodilator Agents | 1997 |
Prostaglandin E2 synthesis is differentially affected by reactive nitrogen intermediates in cultured rat microglia and RAW 264.7 cells.
Topics: Animals; Arachidonic Acid; Cells, Cultured; Cerebral Cortex; Cyclooxygenase 2; Dinoprostone; Enzyme Inhibitors; Isoenzymes; Lipopolysaccharides; Macrophages; Mice; Microglia; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Penicillamine; Prostaglandin-Endoperoxide Synthases; Rats; S-Nitroso-N-Acetylpenicillamine | 1997 |
Disrupted [Ca2+]i homeostasis contributes to the toxicity of nitric oxide in cultured hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Benzamides; Calcium; Cells, Cultured; Cysteine; Cysteine Proteinase Inhibitors; Dipeptides; Embryo, Mammalian; Enzyme Inhibitors; Free Radical Scavengers; Hemoglobins; Hippocampus; Homeostasis; Molsidomine; Neurons; Nitric Oxide; Penicillamine; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; S-Nitrosothiols; Superoxide Dismutase | 1997 |
Nitric oxide does not modulate kainate receptor binding in human brain.
Topics: Brain; Cysteine; Female; Humans; Male; Middle Aged; Molsidomine; Nitric Oxide; Penicillamine; Receptors, Kainic Acid; S-Nitroso-N-Acetylpenicillamine; S-Nitrosothiols | 1997 |
Differential induction of c-fos, c-jun, and apoptosis in lung epithelial cells exposed to ROS or RNS.
Topics: Animals; Apoptosis; Cell Line; Epithelial Cells; Genes, fos; Genes, jun; Hydrogen Peroxide; Lung; Molsidomine; Nitrates; Nitric Oxide; Penicillamine; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Reactive Oxygen Species; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Spermine; Transcription, Genetic | 1997 |
Active site modification of aldose reductase by nitric oxide donors.
Topics: Aldehyde Reductase; Binding Sites; Borohydrides; Catalysis; Diabetes Complications; Diabetes Mellitus; Dithiothreitol; Enzyme Inhibitors; Glyceraldehyde; Humans; Kinetics; Molsidomine; Mutagenesis, Site-Directed; NADP; Nitric Oxide; Nitroprusside; Penicillamine; Placenta; Recombinant Proteins; S-Nitroso-N-Acetylpenicillamine | 1997 |
Nitric oxide reversibly inhibits seven members of the caspase family via S-nitrosylation.
Topics: Animals; Apoptosis; Borates; Cells, Cultured; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytosol; Dactinomycin; Dithiothreitol; Humans; Kinetics; Liver; Male; Mercuric Chloride; Molsidomine; Nitric Oxide; Nitroso Compounds; Penicillamine; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Tumor Necrosis Factor-alpha | 1997 |
Lack of effect of two nitric oxide donors on hydrogen peroxide-induced endothelial barrier dysfunction.
Topics: Animals; Cattle; Cell Membrane Permeability; Cell Survival; Cells, Cultured; Endothelium, Vascular; Hydrogen Peroxide; Molsidomine; Nitric Oxide; Penicillamine; Pulmonary Artery; S-Nitroso-N-Acetylpenicillamine | 1997 |
Nitric oxide donation and nitrite assays in the presence of thiols and albumin as determined by Griess' and Werringloer's methods.
Topics: Amino Acids; Cysteine; Glutathione; Molsidomine; Nitric Oxide; Nitrites; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Serum Albumin, Bovine; Sodium Nitrite; Sulfhydryl Compounds | 1997 |
Nitric oxide donor-induced apoptosis in smooth muscle cells is modulated by protein kinase C and protein kinase A.
Topics: Animals; Aorta; Apoptosis; Cyclic AMP-Dependent Protein Kinases; Membrane Proteins; Molsidomine; Muscle, Smooth, Vascular; Nitric Oxide; Penicillamine; Protein Kinase C; Rabbits; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents | 1997 |
Role of nitric oxide synthase inhibition in the acute hypertensive response to intracerebroventricular cadmium.
Topics: Animals; Arginine; Blood Pressure; Brain Chemistry; Cadmium; Calcium Chloride; Citrulline; Enzyme Inhibitors; Heart Rate; Hypertension; Injections, Intraventricular; Male; Molsidomine; Nitric Oxide Synthase; Penicillamine; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents | 1998 |
The NO/cGMP pathway and the development of neural networks in postembryonic lobsters.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Central Nervous System; Cyclic GMP; Female; Ganglia, Invertebrate; Larva; Molsidomine; Nephropidae; Nerve Net; Nerve Tissue Proteins; Neuronal Plasticity; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Penicillamine; Signal Transduction; Smell | 1998 |
Poly(ADP-ribose) synthetase activation mediates increased permeability induced by peroxynitrite in Caco-2BBe cells.
Topics: Adenosine Triphosphate; Caco-2 Cells; DNA Damage; Humans; Inflammatory Bowel Diseases; Intestinal Mucosa; Molsidomine; Nitrates; Nitric Oxide; Penicillamine; Permeability; Poly(ADP-ribose) Polymerases; S-Nitroso-N-Acetylpenicillamine | 1998 |
Exogenous nitric oxide inhibits mesangial cell adhesion to extracellular matrix components.
Topics: Animals; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Collagen; Cyclic GMP; Cytoskeleton; Extracellular Matrix; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Glomerular Mesangium; Glutathione; Molsidomine; Nitric Oxide; Nitroprusside; Nitroso Compounds; Penicillamine; Protein-Tyrosine Kinases; Rats; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione; Signal Transduction | 1998 |
Nitric oxide donor NOR 3 inhibits ketogenesis from oleate in isolated rat hepatocytes by a cyclic GMP-independent mechanism.
Topics: Adenosine Triphosphate; Animals; Benzoates; Calcium; Cells, Cultured; Cyclic GMP; Imidazoles; Lactic Acid; Liver; Male; Molsidomine; Nitric Oxide; Nitro Compounds; Oleic Acid; Penicillamine; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Sodium Nitrite; Vasodilator Agents | 1998 |
Mechanisms of relaxations of bovine isolated bronchioles by the nitric oxide donor, GEA 3175.
Topics: Albuterol; Aminoquinolines; Animals; Apamin; Bronchi; Bronchodilator Agents; Cattle; Charybdotoxin; Female; Glyburide; Male; Molsidomine; Muscle Relaxation; Nitric Oxide; Oxyhemoglobins; Penicillamine; Peptides; Receptors, Adrenergic, beta-2; Superoxide Dismutase; Triazoles | 1998 |
Inhibitory effect of inducible type nitric oxide synthase on oxidative modification of low density lipoprotein by vascular smooth muscle cells.
Topics: Animals; Cells, Cultured; Copper; Electrophoresis, Agar Gel; Enzyme Induction; Enzyme Inhibitors; Humans; Kinetics; Lipoproteins, LDL; Mice; Molsidomine; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidation-Reduction; Penicillamine; Rats; S-Nitroso-N-Acetylpenicillamine; Sodium-Potassium-Exchanging ATPase | 1998 |
Evidence that different mechanisms underlie smooth muscle relaxation to nitric oxide and nitric oxide donors in the rabbit isolated carotid artery.
Topics: Acetylcholine; Animals; Apamin; Calcimycin; Carotid Arteries; Cell Membrane; Cyclic GMP; Glyburide; In Vitro Techniques; Membrane Potentials; Molsidomine; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Penicillamine; Peptides; Potassium Channel Blockers; Rabbits | 1998 |
Nitric oxide donors protect cultured rat astrocytes from 1-methyl-4-phenylpyridinium-induced toxicity.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Antioxidants; Astrocytes; Cells, Cultured; Free Radicals; Molsidomine; Neuroprotective Agents; Nitric Oxide; Nitroprusside; Penicillamine; Rats; Rats, Sprague-Dawley; Rotenone | 1998 |
Radical releasing properties of nitric oxide donors GEA 3162, SIN-1 and S-nitroso-N-acetylpenicillamine.
Topics: Molsidomine; Nitric Oxide; Oxygen; Penicillamine; Superoxides; Triazoles; Tyrosine | 1998 |
IFN-gamma inhibits AP-1 binding activity in human brain-derived cells through a nitric oxide dependent mechanism.
Topics: Brain; Cell Nucleus; Cells, Cultured; Enzyme Inhibitors; Humans; Interferon-gamma; Molsidomine; Nitric Oxide; omega-N-Methylarginine; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Transcription Factor AP-1 | 1998 |
Inhibition of clotting factor XIII activity by nitric oxide.
Topics: Dose-Response Relationship, Drug; Enzyme Inhibitors; Factor XIII; Glutathione; Humans; Molsidomine; Nitric Oxide; Nitroso Compounds; Penicillamine; Platelet Aggregation Inhibitors; S-Nitrosoglutathione; Spermine | 1998 |
Treatment of Paracoccidioides brasiliensis-infected mice with a nitric oxide inhibitor prevents the failure of cell-mediated immune response.
Topics: Animals; Cell-Free System; Drug Administration Schedule; Immunity, Cellular; Injections, Intraperitoneal; Lung; Lung Diseases, Parasitic; Lymphocyte Activation; Macrophages, Alveolar; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Paracoccidioides; Paracoccidioidomycosis; Penicillamine; Spleen; Tumor Necrosis Factor-alpha | 1998 |
Inhibitory effects of mesoionic 3-aryl substituted oxatriazole-5-imine derivatives on vascular smooth muscle cell mitogenesis and proliferation in vitro.
Topics: Animals; Cell Division; Cells, Cultured; Cyclic GMP; DNA; Male; Molsidomine; Muscle, Smooth, Vascular; Nitric Oxide Donors; Nitrites; Penicillamine; Rats; Rats, Wistar; Signal Transduction; Triazoles; Urea | 1998 |
Nitric oxide donor-induced hyperpermeability of cultured intestinal epithelial monolayers: role of superoxide radical, hydroxyl radical, and peroxynitrite.
Topics: Antioxidants; Caco-2 Cells; Epithelial Cells; Free Radical Scavengers; Glutathione; Humans; Hydroxyl Radical; Intestinal Absorption; Intestines; Kinetics; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Permeability; Superoxide Dismutase; Superoxides | 1998 |
Interaction of nitric oxide donors and ascorbic acid on D-[3H] aspartate efflux from rat striatal slices.
Topics: Animals; Ascorbic Acid; Aspartic Acid; Corpus Striatum; In Vitro Techniques; Kinetics; Male; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Penicillamine; Potassium Cyanide; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Tritium | 1999 |
Lack of interaction between nitric oxide and the redox modulatory site of the NMDA receptor.
Topics: Animals; Binding Sites; Cerebral Cortex; CHO Cells; Cricetinae; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Membrane Potentials; Molsidomine; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Oxidation-Reduction; Patch-Clamp Techniques; Penicillamine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins | 1999 |
In vitro simultaneous measurements of relaxation and nitric oxide concentration in rat superior mesenteric artery.
Topics: Acetylcholine; Animals; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Male; Mesenteric Artery, Superior; Microelectrodes; Molsidomine; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroarginine; Oxyhemoglobins; Penicillamine; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine | 1999 |
Inhibition of bronchoprotective effects of beta2-adrenoceptor agonists by peroxynitrite in guinea pig airways.
Topics: Acetylcholine; Adrenergic beta-Agonists; Airway Resistance; Albuterol; Animals; Bronchoconstriction; Colforsin; Guinea Pigs; Isoproterenol; Male; Molsidomine; Nitrates; Penicillamine; Receptors, Adrenergic, beta-1 | 1999 |
Nitric oxide up-regulates the expression of intercellular adhesion molecule-1 on cancer cells.
Topics: Benzoates; Carcinoma, Squamous Cell; Cell Adhesion Molecules; Free Radical Scavengers; Genistein; Humans; Imidazoles; Intercellular Adhesion Molecule-1; Molsidomine; NF-kappa B; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Penicillamine; Phosphorylation; Promoter Regions, Genetic; Protein Kinase C; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Staurosporine; Tongue Neoplasms; Transcription Factor AP-1; Tumor Cells, Cultured; Up-Regulation | 1999 |
Regulation of intracellular polyamine biosynthesis and transport by NO and cytokines TNF-alpha and IFN-gamma.
Topics: 3T3 Cells; Animals; Biological Transport; Cell Line; Cell Line, Transformed; Dithiothreitol; Enzyme Inhibitors; Interferon-gamma; Kidney Tubules, Proximal; Lysine; Mice; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Ornithine Decarboxylase; Penicillamine; Polyamines; Rats; S-Nitroso-N-Acetylpenicillamine; Tumor Necrosis Factor-alpha | 1999 |
Contrasting roles for nitric oxide and peroxynitrite in the peroxidation of myelin lipids.
Topics: Animals; Central Nervous System; Dinoprost; Encephalomyelitis, Autoimmune, Experimental; F2-Isoprostanes; Lipid Peroxidation; Mice; Molsidomine; Myelin Proteins; Myelin Sheath; Nitrates; Nitric Oxide; Nitric Oxide Donors; Oxidants; Penicillamine | 1999 |
Immunostimulated glial cells potentiate glucose deprivation-induced death of cultured rat cerebellar granule cells.
Topics: Animals; Animals, Newborn; Cell Death; Cells, Cultured; Cerebellum; Coculture Techniques; Excitatory Amino Acid Antagonists; Glial Fibrillary Acidic Protein; Glucose; Interferon-gamma; Kinetics; Lipopolysaccharides; Microtubule-Associated Proteins; Molsidomine; Neuroglia; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitroarginine; Penicillamine; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine | 1999 |
Positive and negative inotropic effects of NO donors in atrial and ventricular fibres of the frog heart.
Topics: Aminoquinolines; Animals; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Half-Life; Heart; Heart Atria; Heart Ventricles; In Vitro Techniques; Molsidomine; Muscle Fibers, Skeletal; Myocardial Contraction; Nitric Oxide Donors; Nitroprusside; Penicillamine; Rana esculenta; S-Nitroso-N-Acetylpenicillamine | 1999 |
Up-regulation of heme-binding protein 23 (HBP23) gene expression by lipopolysaccharide is mediated via a nitric oxide-dependent signaling pathway in rat Kupffer cells.
Topics: Animals; Carrier Proteins; Cell Survival; Cells, Cultured; Cyclic GMP; Cytochrome-B(5) Reductase; Gene Expression Regulation; Heme-Binding Proteins; Hemeproteins; Kinetics; Kupffer Cells; Lipopolysaccharides; Male; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Penicillamine; Protein Biosynthesis; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Transcription, Genetic | 1999 |
Nitric oxide synthase inhibitors enhance 5-HT2 receptor-mediated behavior, the head-twitch response in mice.
Topics: Animals; Arginine; Dextromethorphan; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enzyme Inhibitors; Head Movements; Male; Methylene Blue; Mice; Mice, Inbred ICR; Molsidomine; N-Methylaspartate; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Penicillamine; Receptors, Serotonin; Serotonin; Serotonin Antagonists | 1999 |
Protection against the co-operative toxicity of nitric oxide and oxygen free radicals by overexpression of antioxidant enzymes in bioengineered insulin-producing RINm5F cells.
Topics: Animals; Antioxidants; Catalase; Cytotoxicity, Immunologic; DEET; Drug Synergism; Gene Expression; Glutathione Peroxidase; Hydrogen Peroxide; Hypoxanthine; Islets of Langerhans; Molsidomine; Nitric Oxide Donors; Nitroprusside; Penicillamine; Reactive Oxygen Species; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase; Tumor Cells, Cultured | 1999 |
Inhibitory effect of nitric oxide on chemically induced differentiation of human leukemic K562 cells.
Topics: Antibiotics, Antineoplastic; Cell Division; Erythropoiesis; Humans; K562 Cells; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Penicillamine; RNA, Messenger; Tumor Cells, Cultured | 1999 |
Elevated production of salivary nitric oxide in oral mucosal diseases.
Topics: Adult; Cell Line; Cell Size; Cell Survival; Dose-Response Relationship, Drug; Female; Humans; Lichen Planus, Oral; Male; Molsidomine; Mouth Diseases; Mouth Mucosa; Nitric Oxide; Nitric Oxide Donors; Oral Ulcer; Penicillamine; Saliva; Salivary Glands | 1999 |
Regulation of prostaglandin H2 synthase activity by nitrogen oxides.
Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Cells, Cultured; Cyclooxygenase 1; Enzyme Activation; Enzyme Inhibitors; Free Radical Scavengers; Hydrazines; Isoenzymes; Male; Membrane Proteins; Molsidomine; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Penicillamine; Peroxides; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases; Rats; S-Nitroso-N-Acetylpenicillamine; Sheep; Superoxides | 1999 |
Inhibition of cathepsin K by nitric oxide donors: evidence for the formation of mixed disulfides and a sulfenic acid.
Topics: Animals; Catalysis; Cathepsin K; Cathepsins; CHO Cells; Cricetinae; Disulfides; Dose-Response Relationship, Drug; Enzyme Activation; Gas Chromatography-Mass Spectrometry; Glutathione; Humans; Hydrogen-Ion Concentration; Molsidomine; Nitric Oxide Donors; Nitroprusside; Nitroso Compounds; Penicillamine; Protease Inhibitors; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione; Sulfenic Acids; Time Factors | 1999 |
Different effects of reactive nitrogen intermediates on prostaglandin E2 synthesis in cultured rat microglia and RAW 264.7 cells.
Topics: Animals; Arachidonic Acid; Cell Line; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Enzyme Inhibitors; Isoenzymes; Macrophages; Mice; Microglia; Molsidomine; Monocytes; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; omega-N-Methylarginine; Penicillamine; Prostaglandin-Endoperoxide Synthases; Rats | 1999 |
Possible mechanism of bronchoprotection by SIN-1 in anaesthetized guinea pigs: roles of nitric oxide and peroxynitrite.
Topics: Acetylcholine; Animals; Bronchi; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchodilator Agents; Dose-Response Relationship, Drug; Glutathione; Guinea Pigs; Male; Molsidomine; Nebulizers and Vaporizers; Nitrates; Nitric Oxide; Penicillamine; Rhodamines; Time Factors; Vasodilator Agents | 2000 |
NO(+) but not NO radical relaxes airway smooth muscle via cGMP-independent release of internal Ca(2+).
Topics: 4-Aminopyridine; Animals; Bronchi; Calcium; Calcium-Transporting ATPases; Charybdotoxin; Cyclic GMP; Dithiothreitol; Dogs; Enzyme Activation; Free Radicals; Guanylate Cyclase; Humans; In Vitro Techniques; Molsidomine; Muscle, Smooth; Nitric Oxide; Nitric Oxide Donors; Oxidation-Reduction; Penicillamine; Potassium Channels; Potassium Chloride; Tetraethylammonium; Trachea | 2000 |
Synergistic depletion of astrocytic glutathione by glucose deprivation and peroxynitrite: correlation with mitochondrial dysfunction and subsequent cell death.
Topics: Animals; Astrocytes; Cell Survival; Drug Synergism; Glucose; Glutathione; Membrane Potentials; Mitochondria; Molsidomine; Nitrates; Nitric Oxide Donors; Nitroso Compounds; Penicillamine; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione | 2000 |
Heme oxygenase-1 is a cGMP-inducible endothelial protein and mediates the cytoprotective action of nitric oxide.
Topics: Animals; Cattle; Cell Survival; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Enzyme Induction; Heme Oxygenase (Decyclizing); Molsidomine; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Pulmonary Artery; Second Messenger Systems | 2000 |
Contribution of adenoviral-mediated superoxide dismutase gene transfer to the reduction in nitric oxide-induced cytotoxicity on human islets and INS-1 insulin-secreting cells.
Topics: Adenoviridae; Animals; Cell Survival; Cells, Cultured; Genetic Vectors; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Rats; Superoxide Dismutase; Transfection; Tumor Cells, Cultured | 2000 |
The origin of dinitrosyl-iron complex in endothelial cells.
Topics: Animals; Cells, Cultured; Endothelium, Vascular; Iron; Molsidomine; Nitric Oxide Donors; Nitrogen Oxides; Penicillamine | 2000 |
Major potassium conductance in type I hair cells from rat semicircular canals: characterization and modulation by nitric oxide.
Topics: 4-Aminopyridine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cyclic GMP; Gluconates; Guanylate Cyclase; Hair Cells, Vestibular; Membrane Potentials; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Patch-Clamp Techniques; Penicillamine; Potassium; Potassium Channel Blockers; Rats; Rats, Long-Evans; Semicircular Canals; Signal Transduction | 2000 |
S-nitroso-N-acetylpenicillamine and nitroprusside induce apoptosis in a neuronal cell line by the production of different reactive molecules.
Topics: 1-Methyl-4-phenylpyridinium; Apoptosis; Catalase; Deferoxamine; Flow Cytometry; Hydrogen Peroxide; Molsidomine; Neuroblastoma; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase; Tumor Cells, Cultured | 2000 |
Nitric oxide modulates mechanical strain-induced activation of p38 MAPK in mesangial cells.
Topics: Animals; Biological Transport; Cells, Cultured; Cyclic GMP; Enzyme Activation; Enzyme Inhibitors; Fluorescent Antibody Technique; Glomerular Mesangium; Imidazoles; Mitogen-Activated Protein Kinases; Molsidomine; Nitric Oxide; Nitric Oxide Donors; p38 Mitogen-Activated Protein Kinases; Penicillamine; Pyridines; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Stress, Mechanical | 2000 |
Nitric oxide and peroxynitrite anion modulate liver plasma membrane fluidity and Na(+)/K(+)-ATPase activity.
Topics: Animals; Cell Fractionation; Cell Polarity; Enzyme Activation; Fluorescence Polarization; Liver; Male; Membrane Fluidity; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase | 2000 |
Adaptive responses to peroxynitrite: increased glutathione levels and cystine uptake in vascular cells.
Topics: Adaptation, Physiological; Animals; Cattle; Cells, Cultured; Cystine; Dose-Response Relationship, Drug; Endothelium, Vascular; Free Radical Scavengers; Glutamic Acid; Glutathione; Metalloporphyrins; Molsidomine; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide Donors; Nucleic Acid Synthesis Inhibitors; Penicillamine; Protein Synthesis Inhibitors; S-Nitroso-N-Acetylpenicillamine; Sodium; Superoxide Dismutase | 2000 |
Nitric oxide donors and angiotensin-converting enzyme inhibitors act in concert to inhibit human angiotensin-converting enzyme activity and platelet aggregation in vitro.
Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Enalaprilat; Endothelium, Vascular; Female; Humans; Molsidomine; Nitric Oxide Donors; Penicillamine; Peptidyl-Dipeptidase A; Platelet Aggregation; S-Nitroso-N-Acetylpenicillamine; Umbilical Veins | 2000 |
NO-induced modulation of calcium-oscillations in pulmonary vascular smooth muscle.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Triphosphate; Animals; Caffeine; Calcium; Cyclic GMP-Dependent Protein Kinases; Endothelin-1; Indoles; Isometric Contraction; Male; Molsidomine; Muscle, Smooth, Vascular; Nitric Oxide Donors; Nitroprusside; Penicillamine; Pulmonary Artery; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Sarcoplasmic Reticulum; Vasodilation; Vasodilator Agents | 2000 |
Various nitric oxide donors protect chick embryonic neurons from cyanide-induced apoptosis.
Topics: Animals; Apoptosis; Cell Death; Cells, Cultured; Chick Embryo; Dithiothreitol; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Glutathione; Hydrazines; Kynurenic Acid; Molsidomine; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitrogen Oxides; Nitroglycerin; Nitroprusside; Nitroso Compounds; Penicillamine; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione; Sodium Cyanide | 2000 |
Nitric oxide inhibits Marek's disease virus replication but is not the single decisive factor in interferon-gamma-mediated viral inhibition.
Topics: Animals; Bone Marrow Cells; Cells, Cultured; Chick Embryo; Chickens; Chlorocebus aethiops; Coculture Techniques; COS Cells; Fibroblasts; Herpesvirus 2, Gallid; Interferon-gamma; Macrophages; Molsidomine; Nitric Oxide; Nitric Oxide Donors; omega-N-Methylarginine; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase; Superoxides; Virus Replication | 2000 |
Toxicity of nitric oxide and peroxynitrite to bacterial pathogens of fish.
Topics: Aeromonas; Animals; Bacterial Infections; Catalase; Cell-Free System; Fish Diseases; Free Radical Scavengers; Microbial Sensitivity Tests; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Oncorhynchus mykiss; Oxidants; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase | 2000 |
Mechanisms of nitric oxide-induced cytotoxicity in normal human hepatocytes.
Topics: Adult; Apoptosis; Blotting, Southern; Cell Cycle; Cell Division; Cell Survival; Cells, Cultured; DNA Damage; DNA, Mitochondrial; Dose-Response Relationship, Drug; Electron Transport; Hepatocytes; Humans; Hypoxanthine Phosphoribosyltransferase; Molsidomine; Mutagenicity Tests; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Reactive Oxygen Species | 2001 |
Nitric oxide in the afferent synaptic transmission of the axolotl vestibular system.
Topics: Action Potentials; Ambystoma; Animals; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Hair Cells, Vestibular; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Acid; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Synapses; Synaptic Transmission | 2001 |
Nitric oxide reduces energy supply by direct action on the respiratory chain in isolated cardiomyocytes.
Topics: Adenosine; Alkaloids; Animals; Calcium; Carbazoles; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Electron Transport; Energy Metabolism; Enzyme Inhibitors; Indoles; Molsidomine; Muscle Fibers, Skeletal; Myocardium; NAD; Nitric Oxide; Nitric Oxide Donors; Oxygen Consumption; Penicillamine; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine | 2001 |
NO donors inhibit Leishmania infantum cysteine proteinase activity.
Topics: Animals; Ascorbic Acid; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dithiothreitol; Glutathione; Kinetics; Leishmania infantum; Leupeptins; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitro Compounds; Nitroglycerin; Nitroprusside; Nitroso Compounds; Penicillamine; Protozoan Proteins; S-Nitrosoglutathione | 2001 |
Immunostimulation of rat primary astrocytes decreases intracellular ATP level.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Astrocytes; Central Nervous System; Dose-Response Relationship, Drug; Encephalitis; Enzyme Inhibitors; Inflammation Mediators; Interferon-gamma; Intracellular Fluid; L-Lactate Dehydrogenase; Lipopolysaccharides; Molsidomine; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Penicillamine; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Tumor Cells, Cultured | 2001 |
NO-induced relaxation of labouring and non-labouring human myometrium is not mediated by cyclic GMP.
Topics: Charybdotoxin; Cyclic GMP; Cysteine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Guanylate Cyclase; Humans; In Vitro Techniques; Labor, Obstetric; Molsidomine; Muscle Relaxation; Muscle, Smooth; Myometrium; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Oxadiazoles; Oxytocin; Penicillamine; Peptides; Pregnancy; Quinoxalines; S-Nitrosothiols; Scorpion Venoms; Time Factors; Uterus | 2001 |
Genetic augmentation of nitric oxide synthase increases the vascular generation of VEGF.
Topics: Analysis of Variance; Animals; Cells, Cultured; DEET; Endothelial Growth Factors; Humans; Lymphokines; Molsidomine; Muscle, Smooth, Vascular; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Penicillamine; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transfection; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2001 |
Differential modulation of prostaglandin H synthase-2 by nitric oxide-related species in intact cells.
Topics: Animals; Astrocytes; Brain; Cells, Cultured; Chlorocebus aethiops; COS Cells; Cyclooxygenase 2; Dinoprostone; Gene Expression Regulation, Enzymologic; Isoenzymes; Lipopolysaccharides; Mice; Molsidomine; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroso Compounds; Oxidation-Reduction; Penicillamine; Prostaglandin-Endoperoxide Synthases; S-Nitroso-N-Acetylpenicillamine; Transfection | 2001 |
Killing of lymphoblastic leukemia cells by nitric oxide and taxol: involvement of NF-kappaB activity.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Survival; Cytoskeleton; Drug Synergism; Humans; Leukemia L1210; Leukemia, Lymphoid; Mice; Molsidomine; NF-kappa B; Nitric Oxide; Nitric Oxide Donors; Paclitaxel; Penicillamine; Protein Synthesis Inhibitors; Pyrrolidines; Thiocarbamates; Tumor Cells, Cultured | 2001 |
ATP and nitric oxide modulate a Ca(2+)-activated non-selective cation current in macrovascular endothelial cells.
Topics: Adenosine Triphosphate; Adenylyl Imidodiphosphate; Calcium; Cations; Cell Line; Electrophysiology; Endothelium, Vascular; Humans; Ion Channels; Membrane Potentials; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Umbilical Veins | 2002 |
Effects of nitric oxide donors on vascular endothelial growth factor gene induction.
Topics: Blotting, Northern; Blotting, Western; Cell Nucleus; Dithiothreitol; Dose-Response Relationship, Drug; Endothelial Growth Factors; Genes, Reporter; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Luciferases; Lymphokines; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitroprusside; Oxidation-Reduction; Penicillamine; Plasmids; Promoter Regions, Genetic; Pyridines; Reducing Agents; RNA; RNA, Messenger; S-Nitrosoglutathione; Transcription Factors; Triazenes; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2002 |
Peroxynitrite triggers a delayed resistance of coronary endothelial cells against ischemia-reperfusion injury.
Topics: Acetylcholine; Animals; Coronary Vessels; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Free Radicals; Ischemic Preconditioning, Myocardial; Male; Methionine; Molsidomine; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Peroxynitrous Acid; Rats; Rats, Wistar; Selenomethionine; Uric Acid | 2002 |
Nitric oxide inhibits irreversibly P815 cell proliferation: involvement of potassium channels.
Topics: Animals; Antineoplastic Agents; Cell Count; Cell Division; Coloring Agents; Cytoskeleton; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gentian Violet; Growth Inhibitors; Guanylate Cyclase; Kinetics; Mastocytoma; Mice; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Potassium Channel Blockers; Potassium Channels; Tumor Cells, Cultured | 2002 |
Effect of SNI-2011 on amylase secretion from parotid tissue in rats and in neuronal nitric oxide synthase knockout mice.
Topics: Alkaloids; Amylases; Animals; Azepines; Benzoates; Benzylamines; Calcium; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Carbazoles; Chelating Agents; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Estrenes; Gallic Acid; Genotype; Guanylate Cyclase; Imidazoles; In Vitro Techniques; Indoles; Male; Mice; Mice, Knockout; Molsidomine; Muscarinic Agonists; Myosin-Light-Chain Kinase; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxadiazoles; Parotid Gland; Penicillamine; Phosphodiesterase Inhibitors; Pilocarpine; Protein Kinase Inhibitors; Pyrroles; Pyrrolidinones; Quinoxalines; Quinuclidines; Rats; Rats, Wistar; Sulfonamides; Thiophenes; Type C Phospholipases | 2003 |
Nitric oxide disrupts VE-cadherin complex in murine microvascular endothelial cells.
Topics: Animals; Antigens, CD; Cadherins; Capillary Permeability; Cell Line; Endothelium, Vascular; Macromolecular Substances; Male; Mice; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Penicillamine; RNA, Messenger; Skin | 2003 |
Role of cyclic GMP on inhibition by nitric oxide donors of human eosinophil chemotaxis in vitro.
Topics: Adolescent; Adult; Blotting, Western; Cell Survival; Chemotaxis, Leukocyte; Cyclic GMP; Eosinophils; Female; Humans; In Vitro Techniques; Male; Middle Aged; Molsidomine; N-Formylmethionine Leucyl-Phenylalanine; Nitric Oxide Donors; Nitroprusside; Penicillamine; Tetrazolium Salts; Thiazoles; Tyrosine | 2004 |
Comparison of toxic effects of nitric oxide and peroxynitrite on Uronema marinum (Ciliata: Scuticociliatida).
Topics: Animals; Catalase; Ciliophora; Dose-Response Relationship, Drug; Hemoglobins; Molsidomine; Nitric Oxide Donors; Penicillamine; Superoxide Dismutase | 2004 |
Curcumin overcomes the inhibitory effect of nitric oxide on Leishmania.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Curcumin; Leishmania donovani; Leishmania major; Mice; Mice, Inbred BALB C; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Penicillamine; Peroxynitrous Acid | 2005 |
Peroxynitrite-mediated matrix metalloproteinase-2 activation in human hepatic stellate cells.
Topics: Cell Line; Collagenases; Enzyme Activation; Hepatocytes; Humans; I-kappa B Proteins; Matrix Metalloproteinase 1; Matrix Metalloproteinase 13; Matrix Metalloproteinase 2; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Mitogen-Activated Protein Kinases; Molsidomine; NF-kappa B; NF-KappaB Inhibitor alpha; Nitrates; Penicillamine; Peroxynitrous Acid; Phosphorylation; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1 | 2005 |
Reactive nitrogen species induce nuclear factor-kappaB-mediated protein degradation in skeletal muscle cells.
Topics: Animals; Antioxidants; Cells, Cultured; Metalloendopeptidases; Molsidomine; Muscle Cells; Muscle Fibers, Skeletal; Muscle Proteins; Muscle, Skeletal; Myosin Heavy Chains; NF-kappa B; Nitric Oxide Donors; Penicillamine; Peroxynitrous Acid; Proteasome Endopeptidase Complex; Rats; Reactive Nitrogen Species; Tyrosine; Ubiquitin | 2006 |
Impaired cerebrovascular reactivity after cortical spreading depression in rats: Restoration by nitric oxide or cGMP.
Topics: Analysis of Variance; Animals; Cerebral Cortex; Cerebrovascular Circulation; Cerebrovascular Disorders; Cortical Spreading Depression; Cyclic GMP; Drug Interactions; Hypercapnia; Laser-Doppler Flowmetry; Male; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Rats; Rats, Wistar; Spermine; Thionucleotides; Time Factors | 2006 |
The role of reactive nitrogen species and cigarette smoke in activation of transcription factor NF-kappaB and implication to inflammatory processes.
Topics: Animals; Cell Line; Cells, Cultured; Humans; Inflammation; Lymphocytes; Molsidomine; NF-kappa B; Nicotiana; Nitric Oxide Donors; Penicillamine; Peroxynitrous Acid; Rats; Smoke | 2006 |
Peroxynitrite-mediated oxidative damage to brain mitochondria: Protective effects of peroxynitrite scavengers.
Topics: Aldehydes; Animals; Cell Respiration; Cerebral Cortex; Cyclic N-Oxides; Dose-Response Relationship, Drug; Electron Transport Complex I; Free Radical Scavengers; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Mitochondria; Molsidomine; Nitric Oxide Donors; Oxidative Stress; Oxygen Consumption; Penicillamine; Peroxynitrous Acid; Protein Carbonylation; Spin Labels; Tyrosine | 2007 |
Nitric oxide selectively depletes macrophages in atherosclerotic plaques via induction of endoplasmic reticulum stress.
Topics: Animals; Apoptosis; Atherosclerosis; Caspase 3; Cell Line; Cell Survival; Cells, Cultured; Endoplasmic Reticulum; Eukaryotic Initiation Factor-2; Humans; Macrophages; Mice; Microscopy, Electron; Molsidomine; Myocytes, Smooth Muscle; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Rabbits; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spermine; Thapsigargin; Transcription Factor CHOP; Tunicamycin | 2007 |
Neuroglobin protects against nitric oxide toxicity.
Topics: Animals; Cell Death; Cell Line, Transformed; Dose-Response Relationship, Drug; Globins; Mice; Molsidomine; Nerve Tissue Proteins; Neuroglobin; Neurons; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Transfection | 2008 |
Peroxynitrite has potent pulmonary vasodilator activity in the rat.
Topics: Animals; Dose-Response Relationship, Drug; Male; Molsidomine; Nitric Oxide Donors; Nitroprusside; Oxadiazoles; Penicillamine; Peroxynitrous Acid; Pulmonary Artery; Quinoxalines; Rats; Rats, Sprague-Dawley; Vasodilation; Vasodilator Agents | 2012 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |