penicillamine has been researched along with metallothionein in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (33.33) | 18.7374 |
| 1990's | 6 (28.57) | 18.2507 |
| 2000's | 6 (28.57) | 29.6817 |
| 2010's | 2 (9.52) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rupp, H; Voelter, W; Weser, U | 1 |
| Jones, MM; Pratt, TH | 1 |
| Sternlieb, I | 1 |
| Lamand, M; Mason, J; McQuaid, A | 2 |
| Mason, J; McQuaid, A | 1 |
| Danks, DM; Grimes, A; Kyriakou, P; McArdle, HJ; Mercer, JF | 1 |
| Abel, J; Klein, D; Mullin, CH; Summer, KH | 1 |
| Goering, PL; Klaassen, CD; Tandon, SK | 1 |
| Greim, H; Heilmaier, HE; Jiang, JL; Schramel, P; Summer, KH | 1 |
| Cohen, NL; Hurley, LS; Keen, CL; Lönnerdal, B | 1 |
| Brewer, GJ | 1 |
| Albergoni, V; D'Incà, R; Irato, P; Longo, G; Mestriner, C; Sturniolo, GC | 1 |
| Heinzmann, U; Klein, D; Lichtmannegger, J; Summer, KH | 1 |
| Bando, Y; Chone, Y; Izumi, K; Jiao, Z; Kinouchi, T; Kitaura, K; Minami, T; Mochizuki, M; Ohnishi, Y; Suzuki, Y; Uehara, H; Yamada, T | 1 |
| Borisenko, GG; Fabisiak, JP; Kagan, VE; Kawai, K; Liu, S; Pitt, BR; Quinn, PJ; Tyurin, VA; Tyurina, YY | 1 |
| Lui, EM; Suntres, ZE | 1 |
| Houwen, RH; Linn, FH; van der Kleij, S; van Erpecum, KJ; van Hattum, J | 1 |
| Schilsky, M | 1 |
| Aggarwal, A; Bhatt, M; Chandhok, G; Sauer, V; Schmidt, HH; Schmitt, N | 1 |
| Bragina, O; Järving, I; Kabin, E; Palumaa, P; Plitz, T; Smirnova, J; Tõugu, V | 1 |
3 review(s) available for penicillamine and metallothionein
| Article | Year |
|---|---|
Therapeutic chelating agents.
Topics: Chelating Agents; Deferoxamine; Dimercaprol; Edetic Acid; Humans; Metallothionein; Metals; Penicillamine; Poisoning; Unithiol | 1976 |
The development of cirrhosis in Wilson's disease.
Topics: Ceruloplasmin; Copper; Cornea; Cytosol; Hepatolenticular Degeneration; Humans; Liver; Liver Cirrhosis; Lysosomes; Metallothionein; Mitochondria, Liver; Penicillamine; Prognosis; Protein Binding; Radioisotopes | 1975 |
Practical recommendations and new therapies for Wilson's disease.
Topics: Chelating Agents; Copper; Female; Hepatolenticular Degeneration; Humans; Liver; Metallothionein; Molybdenum; Penicillamine; Pregnancy; Trientine; Zinc | 1995 |
18 other study(ies) available for penicillamine and metallothionein
| Article | Year |
|---|---|
Molecular biology of copper. A circular dichroism study on copper complexes of thionein and penicillamine.
Topics: Animals; Binding Sites; Chickens; Circular Dichroism; Copper; Hydrogen-Ion Concentration; Liver; Metalloproteins; Metallothionein; Penicillamine; Protein Binding; Protein Conformation; Spectrophotometry; Spectrophotometry, Ultraviolet | 1975 |
The interactions of penicillamine with copper in vivo and the effect on hepatic metallothionein levels and copper/zinc distribution: the implications for Wilson's disease and arthritis therapy.
Topics: Animals; Arthritis; Copper; Cytosol; Hepatolenticular Degeneration; Humans; Injections, Intramuscular; Liver; Male; Metallothionein; Methionine; Molybdenum; Organometallic Compounds; Penicillamine; Rats; Rats, Inbred Strains; Reference Values; Zinc | 1992 |
A comparison of the effects of penicillamine, trientine, and trithiomolybdate on [35S]-labeled metallothionein in vitro; implications for Wilson's disease therapy.
Topics: Animals; Copper; Cytosol; Hepatolenticular Degeneration; Liver; Male; Metallothionein; Molybdenum; Penicillamine; Rats; Rats, Inbred Strains; Sulfur Radioisotopes; Trientine | 1991 |
The effect of D-penicillamine on metallothionein mRNA levels and copper distribution in mouse hepatocytes.
Topics: Animals; Cells, Cultured; Chromatography, Liquid; Copper; Dexamethasone; Female; Liver; Metallothionein; Mice; Mice, Inbred Strains; Penicillamine; RNA, Messenger | 1990 |
Metallothionein gene expression in mouse tissues by D-penicillamine.
Topics: Animals; Blotting, Northern; Female; Gene Expression; Metallothionein; Mice; Mice, Inbred C57BL; Penicillamine; RNA, Messenger; Transcription, Genetic | 1988 |
Induction of hepatic metallothionein in mouse liver following administration of chelating agents.
Topics: Animals; Chelating Agents; Dimercaprol; Ditiocarb; Edetic Acid; Liver; Male; Metallothionein; Mice; Nitrilotriacetic Acid; Penicillamine; Pentetic Acid; Succimer | 1985 |
D-penicillamine induces rat hepatic metallothionein.
Topics: Animals; Copper; Liver; Male; Metallothionein; Penicillamine; Rats; Rats, Inbred Strains; Time Factors; Zinc | 1986 |
Molecular localization of copper and zinc in rat fetal liver in dietary and drug-induced copper deficiency.
Topics: Abnormalities, Drug-Induced; Animals; Chromatography, Gel; Copper; Ethylenediamines; Female; Liver; Maternal-Fetal Exchange; Metallothionein; Penicillamine; Pregnancy; Rats; Rats, Inbred Strains; Superoxide Dismutase; Trientine; Zinc | 1984 |
Thiotungstate-copper interactions II. The effects of tetrathiotungstate on systemic copper metabolism in normal and copper-treated rats.
Topics: Animals; Bile; Biological Transport, Active; Ceruloplasmin; Copper; Cytosol; Drug Interactions; Injections, Intraperitoneal; Liver; Male; Metallothionein; Penicillamine; Rats; Rats, Wistar; Subcellular Fractions; Tungsten Compounds; Zinc | 1994 |
Zinc therapy increases duodenal concentrations of metallothionein and iron in Wilson's disease patients.
Topics: Adult; Case-Control Studies; Chelating Agents; Copper; Duodenitis; Duodenum; Female; Hepatolenticular Degeneration; Humans; Intestinal Mucosa; Iron; Male; Metallothionein; Penicillamine; Zinc Sulfate | 1999 |
Dissolution of copper-rich granules in hepatic lysosomes by D-penicillamine prevents the development of fulminant hepatitis in Long-Evans cinnamon rats.
Topics: Animals; Chelating Agents; Copper; Cytoplasmic Granules; Cytosol; Hepatitis, Animal; Liver; Lysosomes; Metallothionein; Microscopy, Electron; Penicillamine; Rats; Rats, Long-Evans; Rats, Wistar | 2000 |
Low susceptibility of Long-Evans Cinnamon rats to N-butyl-N-(4-hydroxybutyl)-nitrosamine-induced urinary bladder carcinogenesis and inhibitory effect of urinary copper.
Topics: Age Factors; Animals; Butylhydroxybutylnitrosamine; Carcinogens; Chelating Agents; Copper; Copper Sulfate; Disease Susceptibility; Hydrogen-Ion Concentration; Iron; Male; Metallothionein; Penicillamine; Rats; Rats, Inbred F344; Rats, Inbred LEC; Rats, Long-Evans; Species Specificity; Urinary Bladder Neoplasms; Urine; Zinc | 2000 |
Nitric oxide-dependent pro-oxidant and pro-apoptotic effect of metallothioneins in HL-60 cells challenged with cupric nitrilotriacetate.
Topics: Annexin A5; Apoptosis; Carcinogens; Caspase 3; Caspases; Chlorides; Chromatography, High Pressure Liquid; Cytochrome c Group; DNA Fragmentation; Electron Spin Resonance Spectroscopy; Enzyme Activation; HL-60 Cells; Humans; Lipid Peroxidation; Metallothionein; Nitric Oxide; Nitric Oxide Donors; Nitrilotriacetic Acid; Organometallic Compounds; Oxidants; Oxidation-Reduction; Penicillamine; Phospholipids; Zinc Compounds | 2001 |
Prooxidative effect of copper--metallothionein in the acute cytotoxicity of hydrogen peroxide in Ehrlich ascites tumour cells.
Topics: Animals; Calcium; Carcinoma, Ehrlich Tumor; Cell Survival; Copper; Copper Sulfate; Deferoxamine; Dose-Response Relationship, Drug; Glutathione Disulfide; Hydrogen Peroxide; Injections, Intraperitoneal; Iron; Lipid Peroxidation; Male; Mannitol; Metallothionein; Mice; Oxidative Stress; Penicillamine; Pinocytosis; Time Factors; Tumor Cells, Cultured; Zinc | 2006 |
Long-term exclusive zinc monotherapy in symptomatic Wilson disease: experience in 17 patients.
Topics: Adolescent; Adult; Bilirubin; Chelating Agents; Copper; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Hepatolenticular Degeneration; Humans; Liver; Longitudinal Studies; Male; Metallothionein; Penicillamine; Trace Elements; Treatment Outcome; Young Adult; Zinc | 2009 |
Zinc treatment for symptomatic Wilson disease: moving forward by looking back.
Topics: Chelating Agents; Copper; Dose-Response Relationship, Drug; Hepatolenticular Degeneration; Humans; Liver; Metallothionein; Penicillamine; Trace Elements; Treatment Outcome; Zinc | 2009 |
The effect of zinc and D-penicillamine in a stable human hepatoma ATP7B knockout cell line.
Topics: Adenosine Triphosphatases; Cation Transport Proteins; Cell Survival; Copper; Copper-Transporting ATPases; Hep G2 Cells; Hepatocytes; Humans; Liver Neoplasms; Metallothionein; Penicillamine; Zinc | 2014 |
Copper(I)-binding properties of de-coppering drugs for the treatment of Wilson disease. α-Lipoic acid as a potential anti-copper agent.
Topics: Apoptosis; Carrier Proteins; Cell Line; Cell Proliferation; Chelating Agents; Copper; Copper Transport Proteins; Hepatocytes; Hepatolenticular Degeneration; Humans; Metallothionein; Penicillamine; Thioctic Acid; Trientine | 2018 |